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Racial disparities in superficial venous disease management: A comparative study of interventions and patient-related outcomes 浅静脉疾病管理中的种族差异:干预措施和患者相关结果的比较研究
IF 6.8 1区 医学 Q1 PERIPHERAL VASCULAR DISEASE Pub Date : 2026-03-01 Epub Date: 2026-03-09 DOI: 10.1016/j.ejvs.2026.02.029
Garyn Metoyer MD , Ethan Chervonski MD, MPH , Giancarlo Speranza MD, MBA , Caron B. Rockman MD , Glenn R. Jacobowitz MD , Thomas S. Maldonado MD , Mikel Sadek MD
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引用次数: 0
Strengthening Clinical Interpretation of SurVeil Paclitaxel Coated Balloon in Femoropopliteal Disease 加强监测紫杉醇包被球囊在股腘动脉疾病中的临床意义。
IF 6.8 1区 医学 Q1 PERIPHERAL VASCULAR DISEASE Pub Date : 2026-03-01 Epub Date: 2025-05-10 DOI: 10.1016/j.ejvs.2025.04.069
Xiaoliang Yin
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引用次数: 0
The Endo-Bentall Procedure in the Treatment of Ascending Aorta Pathologies: A Scoping Review 内本特尔手术治疗升主动脉病变:范围综述。
IF 6.8 1区 医学 Q1 PERIPHERAL VASCULAR DISEASE Pub Date : 2026-03-01 Epub Date: 2025-07-21 DOI: 10.1016/j.ejvs.2025.07.026
Maysam Shehab , Carlota F. Prendes , Anders Wanhainen , Rickard Lindblom , Stefan James , Kevin Mani

Objective

The ascending aorta remains a challenging area for endovascular repair, with limited anatomical suitability of current stent grafts due to proximal landing zone constraints. This scoping review summarised, existing experiences with the Endo-Bentall procedure, evaluated its use across pathologies, identified obstacles, and proposed future advances.

Data Sources

PubMed, Cochrane, and Embase were systematically searched (English language, up to 30 November 2024) for studies evaluating the Endo-Bentall procedure in treating ascending aortic pathologies.

Review Methods

The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol extension for scoping reviews was followed, and data were reported as descriptive narratives or tables.

Results

Twenty studies were included, comprising case reports, anatomical feasibility analyses, reviews, expert opinions, and technical notes. Proof of concept studies in ex vivo (n = 30) and in vivo (n = 20) models achieved 95 – 100% technical success rates, with sustained coronary patency. Five cases were reported; indications included aortic dissection (n = 2), aneurysm (n = 1), and post-surgical complications (n = 2). Balloon expandable transcatheter aortic valve implantation (TAVI) platforms were used in three cases (one used single stage and two used two stage procedures), while self expanding platforms were used in two cases (single stage). Technical success was achieved in all cases. Early follow up showed favourable outcomes in two of three balloon expandable cases and two of two self expanding cases. One patient died at 5 months (non-aortic cause). Anatomical feasibility studies for aortic dissection (n = 547) and aortic aneurysm (n = 80) demonstrated a median suitability rate of 68% (31 – 80%) for various device designs. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology suggested a very low certainty regarding clinical outcomes.

Conclusion

The Endo-Bentall procedure is an emerging endovascular approach for ascending aortic pathologies, particularly for patients at high surgical risk. Early experience suggests feasibility. However, the current literature is significantly limited by publication bias and methodological heterogeneity. Further research is required, with systematic evaluation to optimise device development, surgical technique, bailout strategies, and long term outcomes.
目的:升主动脉仍然是血管内修复的一个具有挑战性的区域,由于近端着陆区的限制,目前支架移植的解剖适应性有限。本综述总结了Endo-Bentall手术的现有经验,评估了其在病理中的应用,确定了障碍,并提出了未来的进展。数据来源:系统检索PubMed、Cochrane和Embase(英文,截止到2024年11月30日),以评估Endo-Bentall手术治疗升主动脉病变的研究。评价方法:遵循系统评价和荟萃分析首选报告项目(PRISMA)协议扩展范围评价,并以描述性叙述或表格的形式报告数据。结果:纳入20项研究,包括病例报告、解剖可行性分析、综述、专家意见和技术说明。在离体(n = 30)和体内(n = 20)模型中进行的概念验证研究取得了95% - 100%的技术成功率,冠脉持续通畅。报告5例;适应症包括主动脉夹层(n = 2),动脉瘤(n = 1),术后并发症(n = 2)。3例采用球囊扩张经导管主动脉瓣植入术(TAVI)平台(1例采用单期手术,2例采用两期手术),2例采用自膨胀平台(单期手术)。在所有情况下都取得了技术上的成功。早期随访显示3例球囊扩张病例中的2例和2例自扩张病例中的2例预后良好。1例患者在5个月时死亡(非主动脉原因)。主动脉夹层(n = 547)和主动脉瘤(n = 80)的解剖学可行性研究表明,各种装置设计的中位适宜率为68%(31 - 80%)。分级推荐评估、发展和评价(GRADE)方法提示临床结果的确定性非常低。结论:Endo-Bentall手术是一种新兴的血管内入路治疗升主动脉病变,特别是对手术风险高的患者。早期的经验表明这是可行的。然而,目前的文献明显受到发表偏倚和方法异质性的限制。需要进一步的研究,通过系统的评估来优化设备开发、手术技术、救助策略和长期结果。
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引用次数: 0
Pre-operative Cilostazol in Patients with Chronic Limb Threatening Ischaemia Associated with Improved Survival after Endovascular Revascularisation 慢性肢体威胁性缺血患者术前西洛他唑与血管内血管重建术后生存率提高相关。
IF 6.8 1区 医学 Q1 PERIPHERAL VASCULAR DISEASE Pub Date : 2026-03-01 Epub Date: 2025-08-20 DOI: 10.1016/j.ejvs.2025.08.035
Alexandra A. Sansosti , Beatrix Choi , Jose Munoz , Imad Aljabban , Nicholas J. Morrissey , Thomas F.X. O’Donnell , Virendra I. Patel

Objective

The study aimed to assess the effect of pre-operative cilostazol on long term survival and peri-operative outcomes in patients with chronic limb threatening ischaemia (CLTI) undergoing endovascular therapy (EVT).

Methods

This retrospective cohort study used the Vascular Quality Initiative registry, including a propensity score adjusted cohort of patients who underwent elective peripheral vascular interventions between 2015 and 2021. Patients were categorised based on pre-operative cilostazol use: cilostazol (PC) group and no cilostazol (NPC) group. The primary outcome was long term (five years) all cause mortality, with secondary outcomes including peri-operative amputation, cardiac complications, and thrombotic or embolic events.

Results

There were 55 457 patients in the NPC group and 3 173 patients in the PC group who underwent EVT and were included in the final cohort. The PC group showed statistically significantly higher long term survival than the NPC group (hazard ratio 0.56, 95% confidence interval [CI] 0.5 – 0.6; p < .001) over a follow up period of five years. The PC group also demonstrated lower rates of peri-operative amputation compared with the NPC group (odds ratio 0.69, 95% CI 0.6 – 0.8; p < .001). No other differences were found for peri-operative outcomes between groups.

Conclusion

Pre-operative cilostazol use in patients with CLTI undergoing EVT was associated with improved long-term survival and reduced peri-operative amputation rates. These findings suggest a potential benefit of cilostazol in this high-risk population, justifying further dedicated, prospective studies.
目的:本研究旨在评估术前西洛他唑对接受血管内治疗(EVT)的慢性肢体威胁性缺血(CLTI)患者长期生存和围手术期预后的影响。方法:本回顾性队列研究利用血管质量倡议登记处,包括2015年至2021年间接受选择性外周血管干预的倾向评分调整队列患者。根据术前西洛他唑的使用情况将患者分为西洛他唑(PC)组和未使用西洛他唑(NPC)组。主要结局是长期(5年)全因死亡率,次要结局包括围手术期截肢、心脏并发症和血栓或栓塞事件。结果:NPC组55457例、PC组3173例患者行EVT纳入最终队列。PC组的长期生存率显著高于NPC组(风险比0.56,95%可信区间[CI] 0.5 ~ 0.6; p)。结论:行EVT的CLTI患者术前使用西洛他唑可提高长期生存率,降低围手术期截肢率。这些发现表明西洛他唑在这一高危人群中的潜在益处,证明了进一步专门的前瞻性研究是合理的。
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引用次数: 0
Patients with Ocular Ischaemic Events Have Greater Cerebral White Matter Hyperintensity Volume than Asymptomatic Patients Undergoing Carotid Revascularisation 有眼部缺血事件的患者比接受颈动脉血管重建术的无症状患者有更大的脑白质高强度。
IF 6.8 1区 医学 Q1 PERIPHERAL VASCULAR DISEASE Pub Date : 2026-03-01 Epub Date: 2025-08-19 DOI: 10.1016/j.ejvs.2025.08.033
Simone J.A. Donners , Saskia I. Willemsen , Edwin Bennink , Stefan Saicic , Christoph Knappich , Jeroen Hendrikse , Constantijn E.V.B. Hazenberg , Raechel J. Toorop , Gert J. de Borst

Objective

Carotid artery stenosis may cause ocular ischaemic events (OIE) due to thrombo-embolic events or reduced perfusion to the ophthalmic arteries. While these patients have a lower risk of recurrent ipsilateral ischaemic events compared with patients with hemispheric events, the potential relationship between OIE and cerebral white matter hyperintensities (WMHs), as a manifestation of small vessel disease, has not been explored. This study investigated the presence of WMHs in patients with OIE compared with asymptomatic patients with carotid artery stenosis scheduled for carotid revascularisation.

Methods

A retrospective analysis of patient and pre-operative imaging data from January 2003 to February 2022 was conducted at two large tertiary referral stroke centres. The primary outcome was presence and severity of WMHs, according to the Fazekas scale score and quantitative volume measurements using fluid attenuated inversion recovery imaging of the hemisphere corresponding to the treated and non-treated arteries. Analyses were performed using logistic and linear regression.

Results

A total of 203 patients (108 asymptomatic, 95 with OIE) were included. Among those with OIE, 76 experienced transient monocular vision loss, 11 had retinal artery occlusion, and eight had ocular ischaemic syndrome. Fazekas scores were comparable between asymptomatic patients and those with OIE. In both groups, WMH was more pronounced in the periventricular white matter compared with the deep white matter. Multivariable linear regression analysis adjusted for patient demographics, cerebrovascular risk factors, and silent brain infarcts further revealed that patients with OIE had statistically significantly higher log transformed WMH volumes than asymptomatic patients in both the hemisphere corresponding to the treated artery (β 0.62, 95% confidence interval [CI] 0.05 – 1.18) and the hemisphere corresponding to the non-treated artery (β 1.04, 95% CI 0.41 – 1.67).

Conclusion

Patients with OIE showed higher WMH volumes compared with asymptomatic patients. This may reflect an increased vulnerability to subclinical cerebral small vessel disease, supporting the potential role of intensified brain protective strategies, such as stricter lifestyle modification and more aggressive cardiovascular risk management, in addition to the prevention of ocular ischaemia.
目的:颈动脉狭窄可引起眼缺血事件(OIE),原因是血栓栓塞事件或眼动脉灌注减少。虽然这些患者复发同侧缺血事件的风险低于半球事件患者,但OIE与作为小血管疾病表现的脑白质高信号(WMHs)之间的潜在关系尚未探讨。本研究将颈动脉狭窄的无症状患者与计划行颈动脉血管重建术的颈动脉狭窄患者进行比较。方法:回顾性分析两家大型三级转诊卒中中心2003年1月至2022年2月的患者和术前影像学资料。根据Fazekas评分和使用治疗和未治疗动脉对应半球的液体衰减反转恢复成像进行定量体积测量,主要结局是WMHs的存在和严重程度。采用逻辑回归和线性回归进行分析。结果:共纳入203例患者(无症状108例,有OIE 95例)。在OIE患者中,76人有短暂性单眼视力丧失,11人有视网膜动脉闭塞,8人有眼缺血综合征。Fazekas评分在无症状患者和OIE患者之间具有可比性。在两组中,与深部白质相比,WMH在心室周围白质中更为明显。多变量线性回归分析校正了患者人口统计学、脑血管危险因素和无症状脑梗死,进一步显示OIE患者在治疗动脉对应的半球(β 0.62, 95%可信区间[CI] 0.05 - 1.18)和未治疗动脉对应的半球(β 1.04, 95% CI 0.41 - 1.67)的log转化WMH体积均显著高于无症状患者。结论:OIE患者WMH体积高于无症状患者。这可能反映了亚临床脑小血管疾病的易感性增加,支持强化脑保护策略的潜在作用,如更严格的生活方式改变和更积极的心血管风险管理,以及预防眼部缺血。
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引用次数: 0
The Delphi Process and Vascular Surgical Practice- Creating Clarity or Contributing to Chaos? 德尔菲过程和血管外科实践:创造清晰还是助长混乱?
IF 6.8 1区 医学 Q1 PERIPHERAL VASCULAR DISEASE Pub Date : 2026-03-01 Epub Date: 2025-09-29 DOI: 10.1016/j.ejvs.2025.09.050
Ian Loftus, James Black
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引用次数: 0
Incidence of Post-operative Delirium in Patients Undergoing Procedures for Chronic Limb Threatening Ischaemia: Evidence for Cognitive Screening? 慢性肢体威胁性缺血患者术后谵妄的发生率:认知筛查的证据?
IF 6.8 1区 医学 Q1 PERIPHERAL VASCULAR DISEASE Pub Date : 2026-03-01 Epub Date: 2025-10-28 DOI: 10.1016/j.ejvs.2025.10.052
John S.M. Houghton , Amirah Essop-Adam , Laura J. Gray , Harjeet S. Rayt , Rob D. Sayers , Victoria J. Haunton
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引用次数: 0
Mapping the European Society for Vascular Surgery Carotid Guidelines to Swissvasc: A Model for Evidence Based Registry Improvement 映射欧洲血管外科学会颈动脉指南到瑞士vasc:一个基于证据的注册改进模型。
IF 6.8 1区 医学 Q1 PERIPHERAL VASCULAR DISEASE Pub Date : 2026-03-01 Epub Date: 2025-10-26 DOI: 10.1016/j.ejvs.2025.10.042
Philippe Stauffer , Benedikt Reutersberg , Alexander Zimmermann , Lorenz Meuli
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引用次数: 0
Expanding the View: Insights into Methodological and Clinical Aspects of the TRANSCEND Study 扩大视野:对TRANSCEND研究的方法学和临床方面的见解。
IF 6.8 1区 医学 Q1 PERIPHERAL VASCULAR DISEASE Pub Date : 2026-03-01 Epub Date: 2025-05-10 DOI: 10.1016/j.ejvs.2025.05.008
Katharina Kurzmann-Guetl, Marianne Brodmann, Peter A. Schneider
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引用次数: 0
Vascular Graft and Endograft Infections: A Delphi Consensus Document on Terminology, Definitions, Treatment, Outcomes, Follow Up, and Reporting Standards 血管移植物和内移植物感染:关于术语、定义、治疗、结果、随访和报告标准的德尔菲共识文件。
IF 6.8 1区 医学 Q1 PERIPHERAL VASCULAR DISEASE Pub Date : 2026-03-01 Epub Date: 2025-07-29 DOI: 10.1016/j.ejvs.2025.07.044
Karl Sörelius , Robin Verhoek , Xavier Berard , Oliver T.A. Lyons , Mathilde Puges , Thomas R. Wyss , International Expert Panel on Vascular Graft and Endograft Infections , European Society for Vascular Surgery Clinical Practice Guidelines on the Management of Vascular Graft and Endograft Infections Writing Committee

Objective

There is a lack of consensus on certain terminology and definitions related to vascular graft and endograft infections (VGEIs) and secondary aorto-enteric erosion and or fistula and their treatment, outcome reporting, follow up, and reporting standards. The objective of this study was to complete a Delphi consensus study on these VGEI related issues.

Methods

The Delphi methodology was used with a panel of 43 international experts (specialists in vascular or cardiovascular surgery, infectious diseases, nuclear medicine, and radiology). Four Delphi rounds were planned using an online questionnaire initially with 31 statements. Panellists rated the statements on a five point Likert scale. Comments on statements were analysed, statements were revised, added, or deleted, and the results were presented in iterative rounds. Consensus was defined as ≥ 75% of the panel rating a statement as strongly agree or agree on the Likert scale, and consensus on the final assessment was defined as Cronbach’s α > 0.80. Reporting was performed according to the ACcurate COnsensus Reporting Document (ACCORD) guideline.

Results

All 43 panellists fulfilled all four rounds, resulting in 100% participation. Cronbach’s α increased through the rounds: round 1, 0.88; round 2, 0.89; round 3, 0.90; and round 4, 0.90. A final fifth round was performed among all surgeons (n = 27) defining secondary aorto-enteric erosion and or fistula, with 100% participation. Agreement was reached for 29 final statements: two on need for consensus, two on definition of multidisciplinary team, three on microbiology diagnosis, six on treatment, three on secondary graft-enteric partial erosion, secondary graft-enteric fistula, and secondary aorto-enteric fistula, three on treatment outcomes, nine on follow up, and one on reporting standards including 11 items.

Conclusion

Consensus was achieved for 29 statements, which were developed to establish a common perception of VGEI and secondary aorto-enteric erosion and or fistula, with the potential to improve research in this field and ultimately patient care.
目的:关于血管移植物和移植物感染(VGEIs)和继发性主动脉肠侵蚀/瘘及其治疗、结果报告、随访和报告标准的某些术语和定义缺乏共识。本研究的目的是完成对这些VGEI相关问题的德尔菲共识研究。方法:由43名国际专家(血管或心血管外科、传染病、核医学和放射学专家)组成的小组采用德尔菲法。最初计划使用一份包含31个陈述的在线问卷进行四轮德尔菲调查。小组成员以5分的李克特量表对这些陈述进行评分。对陈述的评论进行了分析,对陈述进行了修改、添加或删除,并在迭代的回合中提出了结果。共识定义为≥75%的专家组在李克特量表上对陈述的评价为强烈同意或同意,最终评估的共识定义为Cronbach's α > 0.80。根据准确一致报告文件(ACCORD)指南进行报告。结果:所有43名小组成员完成了所有四轮,100%参与。Cronbach’s α随轮次增加:第1轮,0.88;第二轮,0.89;第三轮,0.90;第4轮,0.90。在所有外科医生(n = 27)中进行最后的第五轮检查,确定继发性主动脉-肠侵蚀/瘘管,100%参与。29项最终声明达成一致:2项共识,2项多学科团队定义,3项微生物学诊断,6项治疗,3项继发性移植物-肠部分糜烂/继发性移植物-肠瘘/继发性主动脉-肠瘘,3项治疗结果,9项随访,1项报告标准,共11项。结论:29个陈述达成共识,这些陈述建立了VGEI和继发性主动脉-肠侵蚀/瘘的共同认知,具有改进该领域研究和最终患者护理的潜力。
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引用次数: 0
期刊
European Journal of Vascular and Endovascular Surgery
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