British Journal of Oral & Maxillofacial Surgery最新文献

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Bacterial involvement in the development of oral squamous cell carcinoma and onset of oral potentially malignant disorders: metagenomic analysis of the microbiome 细菌参与口腔鳞状细胞癌的发展和口腔潜在恶性疾病的发病：微生物组的宏基因组分析

IF 1.9 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

British Journal of Oral & Maxillofacial Surgery

Pub Date : 2025-12-01 DOI: 10.1016/j.bjoms.2025.09.072

Atsumu Kouketsu

引用次数: 0

Immunohistochemical evaluation of Ki67 in predicting malignant transformation in oral submucous fibrosis 免疫组化评价Ki67预测口腔黏膜下纤维化恶性转化。

IF 1.9 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

British Journal of Oral & Maxillofacial Surgery

Pub Date : 2025-12-01 DOI: 10.1016/j.bjoms.2025.07.007

K.A. Kamala , S. Sankethguddad , Mohmed Isaqali Karobari

Oral submucous fibrosis (OSMF) is a potentially malignant disorder with a risk of progressing to oral squamous cell carcinoma. A key indicator of malignant transformation is increased and uncontrolled cell proliferation, which can be evaluated using markers such as Ki67. This study aimed to assess Ki67 expression in OSMF, compare its levels across different associated habits, and correlate expression with clinical and histological grading. This prospective study included 180 histopathologically confirmed cases, divided into three groups: 60 each of oral submucous fibrosis, oral squamous cell carcinoma, and normal oral mucosa. Immunohistochemistry was performed on 3 µm thick formalin-fixed, paraffin-embedded tissue sections using a monoclonal Ki67 antibody (clone MIB-1). Statistical analysis was conducted using SPSS version 21, and chi squared tests were applied, with significance set at p < 0.05. High Ki67 expression was observed in 51 of 60 Oral submucous fibrosis cases, significantly greater than in normal oral mucosa and slightly lower than in oral squamous cell carcinoma, where 57 of 60 cases showed high expression. A statistically significant correlation was found between Ki67 expression and high-risk habits, clinical stages, and histological grades (p < 0.05). The progressive rise in Ki67 expression from normal oral mucosa to oral submucous fibrosis and oral squamous cell carcinoma underscores its role as a biomarker for malignant transformation. While not a direct cause, elevated Ki67 reflects increased proliferative activity and malignancy risk. These findings highlight the utility of Ki67 in early detection, prognosis, and monitoring of oral submucous fibrosis patients to prevent malignant progression.

口腔黏膜下纤维化（OSMF）是一种潜在的恶性疾病，有进展为口腔鳞状细胞癌的风险。恶性转化的一个关键指标是细胞增殖增加和不受控制，这可以用Ki67等标志物来评估。本研究旨在评估Ki67在OSMF中的表达，比较其在不同相关习惯中的表达水平，并将表达与临床和组织学分级相关联。本前瞻性研究纳入180例经组织病理学证实的病例，分为三组：口腔黏膜下纤维化、口腔鳞状细胞癌和正常口腔黏膜各60例。使用单克隆Ki67抗体（克隆为MIB-1）对3µm厚的福尔马林固定石蜡包埋组织切片进行免疫组化。采用SPSS version 21进行统计分析，采用卡方检验，显著性设为p

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引用次数: 0

A scoping review of formal leadership training in maxillofacial surgery. Are we nurturing or neglecting tomorrow’s leaders? 颌面外科正式领导训练的范围检讨。我们是在培养还是忽视未来的领导者？

IF 1.9 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

British Journal of Oral & Maxillofacial Surgery

Pub Date : 2025-12-01 DOI: 10.1016/j.bjoms.2025.07.016

Jonathan James , Lara Watson , Satheesh Prabhu

Leadership is increasingly recognised as an essential non-technical skill for effective surgical practice, particularly in oral and maxillofacial surgery (OMFS) due to its multidisciplinary nature and clinical scope. The aim of this review is to identify current leadership development opportunities available to UK OMFS specialty trainees, evaluate their sufficiency, and propose areas for improvement. A comprehensive search of published and grey literature was conducted, screening 2796 articles, with 18 meeting the inclusion criteria. Fourteen leadership opportunities were identified; however, most were generic rather than OMFS-specific, comprising formal programmes, committee roles, and e-learning modules. In comparison, allied surgical specialties such as ENT, Plastic Surgery, and Orthopaedics offer more targeted leadership programmes supported by dedicated funding and structured mentorship. To improve OMFS training, this review recommends the development of specialty-specific leadership programmes that are integrated into clinical practice and complemented by formal mentorship initiatives through organisations such as BAOMS. These steps are vital for cultivating future OMFS leaders, ensuring the specialty’s continued growth, and ultimately enhancing patient care.

由于其多学科性质和临床范围，领导能力越来越被认为是有效外科实践中必不可少的非技术技能，特别是在口腔颌面外科（OMFS）中。本次审查的目的是确定英国OMFS专业学员目前可用的领导力发展机会，评估其充分性，并提出改进的领域。综合检索已发表文献和灰色文献，筛选2796篇，其中18篇符合纳入标准。确定了14个领导机会；然而，大多数是一般性的，而不是针对omfs的，包括正式方案、委员会角色和电子学习模块。相比之下，联合外科专业，如耳鼻喉科、整形外科和骨科，提供更有针对性的领导力课程，由专门的资金和结构化的指导支持。为了改进OMFS培训，本综述建议制定专门的领导力计划，将其整合到临床实践中，并通过BAOMS等组织进行正式的指导计划。这些步骤对于培养未来的OMFS领导者，确保专业的持续发展，并最终提高患者护理水平至关重要。

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引用次数: 0

New classification system for osteoradionecrosis of the jaws – An integrative review 颌骨放射性骨坏死的新分类体系综述。

IF 1.9 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

British Journal of Oral & Maxillofacial Surgery

Pub Date : 2025-12-01 DOI: 10.1016/j.bjoms.2025.09.001

Cæcilie Havndrup-Pedersen, Sanne Werner Møller Andersen, Jan Nyberg, Thomas Kofod

The aim of this paper was to present an overview of the previous published classification and staging systems for osteoradionecrosis (ORN) of the jaws and propose a new classification system for ORN. An electronic search was conducted using Medical Subject Headings (MeSH) terms, ‘osteoradionecrosis’ and ‘classification’, and free text words, ‘stage’, ‘staging’, ‘ORN’, classification’. A total of 2053 manuscripts were identified, of which 21 were included, reviewed, and analysed by all authors. A total of 21 different classification and staging systems were identified. Objective findings, included exposed bone and/or fistula, as well as radiological evidence of pathological fracture, were the three most used factors in the existing classification and staging systems (57.1%, 38%, 52.4%). Nine classification and staging systems (42.9%) were treatment-dependent. Fourteen out of the 21 (66.7%) classification and staging systems only described changes in the mandible. Notably, only one article described changes in the maxilla. No standardised classification or staging system has to our knowledge addressed the complexity of ORN. There is a clear need for a new classification and staging system that enables the monitoring of disease progression, evaluation of treatment outcomes, restaging, and comparison of different treatment approaches. We propose a new classification system to address these unmet needs.

本文的目的是对以往发表的颌骨放射性骨坏死（ORN）的分类和分期系统进行综述，并提出一种新的ORN分类系统。使用医学主题标题（MeSH）术语“骨放射性坏死”和“分类”以及自由文本词“阶段”、“分期”、“ORN”、“分类”进行电子搜索。共有2053份手稿被确定，其中21份被所有作者纳入、审查和分析。共确定了21种不同的分类和分期系统。客观发现，包括暴露的骨和/或瘘管，以及病理性骨折的影像学证据，是现有分类和分期系统中使用最多的三个因素（57.1%,38%,52.4%）。9个分类和分期系统（42.9%）依赖于治疗。21个分类和分期系统中有14个（66.7%）只描述了下颌骨的变化。值得注意的是，只有一篇文章描述了上颌骨的变化。据我们所知，没有标准化的分类或分期系统来解决ORN的复杂性。显然需要一种新的分类和分期系统，以便监测疾病进展、评估治疗结果、重新分期和比较不同的治疗方法。我们提出了一个新的分类系统来解决这些未满足的需求。

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引用次数: 0

Is hypothyroidism corrected prior to head and neck surgery: an audit 头颈部手术前甲状腺功能减退是否得到纠正：审计

IF 1.9 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

British Journal of Oral & Maxillofacial Surgery

Pub Date : 2025-12-01 DOI: 10.1016/j.bjoms.2025.09.065

Zaid

引用次数: 0

Combined application of digital surgery group versus traditional experience group in head and neck reconstruction: a retrospective controlled study 数字手术组与传统经验组在头颈部重建术中的联合应用回顾性对照研究

IF 1.9 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

British Journal of Oral & Maxillofacial Surgery

Pub Date : 2025-12-01 DOI: 10.1016/j.bjoms.2025.09.023

Chao Li

引用次数: 0

Effects of preoperative chemotherapy on mandibular reconstruction using computer-aided design/computer-aided manufacturing 术前化疗对计算机辅助设计/计算机辅助制造下颌骨重建的影响

IF 1.9 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

British Journal of Oral & Maxillofacial Surgery

Pub Date : 2025-12-01 DOI: 10.1016/j.bjoms.2025.09.046

Nobuhiro Hanai

引用次数: 0

Surgical repair of labial defect 唇部缺损的外科修复

IF 1.9 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

British Journal of Oral & Maxillofacial Surgery

Pub Date : 2025-12-01 DOI: 10.1016/j.bjoms.2025.09.036

Habi Mahmoud Abdelatif

引用次数: 0

Restorabite™: Phase II trial of jaw stretching exercises using a novel device for patients with trismus following head and neck cancer Restorabite™：使用一种新型器械治疗头颈癌后唇腭裂的II期临床试验

IF 1.9 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

British Journal of Oral & Maxillofacial Surgery

Pub Date : 2025-12-01 DOI: 10.1016/j.bjoms.2025.09.010

Emma Charters

引用次数: 0

Comparison of complications in open tracheostomy in low-dose aspirin 低剂量阿司匹林开气管切开术并发症的比较

IF 1.9 4区医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

British Journal of Oral & Maxillofacial Surgery

Pub Date : 2025-12-01 DOI: 10.1016/j.bjoms.2025.09.020

Napadon Tangjaturonrasme

引用次数: 0

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