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The Role of Insomnia and Exercise in COVID-19 Worries for Psychological Distress in Hong Kong Chinese: A Moderated Mediation Model. 失眠和锻炼在新冠肺炎对香港中国人心理困扰的担忧中的作用:一个温和的调解模型。
IF 3.1 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-05-01 Epub Date: 2023-10-16 DOI: 10.1080/15402002.2023.2270095
Branda Yee-Man Yu, Chun Sing Lam, Katy Yuen Yan Tam, Denise Shuk Ting Cheung, Shu Cheng Chen, Wing Fai Yeung

Objective: To examine the role of insomnia as a mediator between worrying and mental health and whether the association between worrying and insomnia is moderated by the levels of exercise frequency.

Methods: A cross-sectional online survey was conducted during the fourth wave of the COVID-19 outbreak in Hong Kong (n = 988). Participants' insomnia, psychological distress, and exercise frequency were evaluated. A mediation analysis was performed to examine the direct effect of COVID-19 worries and their indirect effect through insomnia on psychological distress.

Results: A significant indirect effect of COVID-19 worries through insomnia was found on psychological distress (beta = 0.18, SE = 0.02, 95% CI = 0.14-0.22, p < .001). The significant index of moderated mediation supported the moderating effect of exercise frequency on the indirect effect of COVID-19 worries on psychological distress (IMM = 0.06, SE = 0.02, 95% CI = 0.02-0.10, p = .006). The conditional indirect effects of insomnia on psychological distress were significant in individuals with mean and higher exercise frequency but not in those with lower exercise frequency.

Conclusion: COVID-19 worries increased psychological distress through the worsening of sleep, and such an array of COVID-19 worries on insomnia was moderated by exercise frequency. Engaging more frequent exercise could reduce insomnia in people with less COVID-19 worries.

目的:研究失眠在焦虑与心理健康之间的中介作用,以及焦虑与失眠之间的关系是否受运动频率水平的调节。方法:在香港第四波新冠肺炎疫情期间进行横断面在线调查(n = 988)。对参与者的失眠、心理困扰和运动频率进行评估。对新冠肺炎担忧的直接影响及其通过失眠对心理困扰的间接影响进行了中介分析。结果:发现新冠肺炎焦虑通过失眠对心理困扰有显著的间接影响(β = 0.18,SE = 0.02,95%CI = 0.14-0.22,p p = .006)。失眠对心理困扰的条件间接影响在平均运动频率和较高运动频率的个体中显著,但在较低运动频率的群体中不显著。结论:新冠肺炎焦虑通过睡眠的恶化而增加心理压力,而运动频率对新冠肺炎对失眠的一系列担忧起到了调节作用。更频繁地锻炼可以减少新冠肺炎担忧较少的人的失眠。
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引用次数: 0
"Tell Me More About Your Child's Sleep": A Qualitative Investigation Of Sleep Problems In Children With ADHD. "告诉我更多关于您孩子睡眠的信息":对多动症儿童睡眠问题的定性调查。
IF 3.1 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-05-01 Epub Date: 2023-09-04 DOI: 10.1080/15402002.2023.2253947
Upasana Bondopadhyay, Jane McGrath, Andrew N Coogan

Objective: To investigate parental experiences and perceptions of sleep problems in their children with Attention Deficit Hyperactivity Disorder (ADHD), the perceived impacts of sleep problems and coping strategies deployed by parents.

Methods: Semi-structured interviews with twenty-six parents of pre-adolescent children with a diagnosis of ADHD, followed by thematic analysis of the interview transcripts.

Results: Three themes were generated from the data: Children's Sleep Difficulties; Impacts of Children's Sleep; and Improving Children's Sleep. Sleep initiation problems in children with ADHD were commonly reported by parents, were perceived to be linked in a bidirectional manner with executive and emotional problems, and were reported as being disruptive to parental sleep. Some parents reported that their children's sleep problems were the initial prompt that lead to a diagnosis of ADHD. Parents reported utilizing a range of coping strategies to mitigate sleep problems, such as controlling the bedroom sensory environment and using emotional "wind down" as part of the bedtime routine. Some parents endorsed a beneficial effect of melatonin on their children's sleep.

Conclusions: Sleep problems in children with ADHD were perceived as important issues by parents. Equipping parents with evidence-based strategies for the management of their children's sleep may lead to benefits for the children, parents and wider household.

目的调查家长对患有注意力缺陷多动障碍(ADHD)儿童睡眠问题的经历和看法、睡眠问题的影响以及家长采取的应对策略:方法:对 26 名被诊断患有注意力缺陷多动障碍(ADHD)的青春期前儿童的家长进行半结构式访谈,然后对访谈记录进行主题分析:结果:从数据中产生了三个主题:儿童睡眠困难;儿童睡眠的影响;改善儿童睡眠。多动症儿童的入睡问题是家长们普遍报告的问题,被认为与执行力和情绪问题有双向联系,并被报告为干扰了家长的睡眠。一些家长表示,孩子的睡眠问题是导致诊断为多动症的最初诱因。家长们报告说,他们采用了一系列应对策略来缓解睡眠问题,如控制卧室的感官环境,以及在睡前例行活动中使用情绪 "放松"。一些家长认可褪黑激素对儿童睡眠的有益影响:结论:多动症儿童的睡眠问题被家长视为重要问题。让家长掌握以证据为基础的儿童睡眠管理策略,可为儿童、家长和整个家庭带来益处。
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引用次数: 0
Overnight Heart Rate Variability During Sleep Disturbance In Peri- And Postmenopausal Women. 围绝经期和绝经后妇女睡眠紊乱期间的隔夜心率变异性
IF 3.1 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-05-01 Epub Date: 2023-09-06 DOI: 10.1080/15402002.2023.2255329
Irina Virtanen, Päivi Polo-Kantola, Nea Kalleinen

Objectives: Disturbed sleep, common during the climacteric, is associated with increased sympathetic activity, a cardiovascular risk factor. We evaluated sleep disturbance effect on autonomic nervous function in climacteric women.

Methods: Seventeen perimenopausal and 18 postmenopausal women underwent a sleep study protocol: an adaptation night, a reference night, and a sleep disturbance night, with a hand loosely tied to the bed to allow blood sampling. This procedure was repeated after six months of menopausal hormone therapy (MHT) or placebo. Sleep disturbance and MHT effects on overnight heart rate variability (HRV) were analyzed.

Results: At baseline, sleep disturbance increased vagal HRV in postmenopausal women, but no changes were seen in perimenopausal women. At six months, sleep disturbance increased total HRV power in the perimenopausal placebo group, and increased nonlinear vagal HRV in the postmenopausal placebo group, but no other changes were seen. MHT did not have any effects on HRV, neither at perimenopause nor at postmenopause.

Conclusions: External sleep disturbance had only minor effects on HRV across menopause. MHT had no detectable HRV effects.

目的:睡眠紊乱在女性更年期很常见,与交感神经活动增加有关,而交感神经活动增加是心血管风险因素之一。我们评估了睡眠障碍对高潮期女性自律神经功能的影响:17名围绝经期妇女和18名绝经后妇女接受了睡眠研究方案:一个适应之夜、一个参照之夜和一个睡眠障碍之夜。在接受更年期荷尔蒙疗法(MHT)或安慰剂治疗六个月后,重复这一过程。分析了睡眠障碍和 MHT 对夜间心率变异性(HRV)的影响:结果:基线时,睡眠障碍会增加绝经后妇女迷走神经的心率变异性,但围绝经期妇女的心率变异性没有变化。六个月后,睡眠障碍增加了围绝经期安慰剂组的总心率变异功率,增加了绝经后安慰剂组的非线性迷走心率变异,但未发现其他变化。无论是在围绝经期还是绝经后,MHT对心率变异都没有任何影响:结论:外部睡眠障碍对整个绝经期的心率变异只有轻微影响。MHT对心率变异没有可检测到的影响。
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引用次数: 0
Race as a Potential Moderator of the Association between Dysfunctional Beliefs about Sleep and Global Sleep Health. 种族是睡眠障碍信念与全球睡眠健康之间关系的潜在调节因素。
IF 3.1 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-05-01 Epub Date: 2023-09-06 DOI: 10.1080/15402002.2023.2255328
Spencer A Nielson, Natalie D Dautovich, Joseph M Dzierzewski

Objectives: Dysfunctional beliefs about sleep are associated with components of sleep health, but their association with global sleep health is understudied. Beliefs about sleep may systematically vary by race, which may influence the association between dysfunctional beliefs about sleep and global sleep health. This study aimed to investigate whether race influences the association between dysfunctional beliefs about sleep and global sleep health.

Methods: Data were collected as part of an online survey. Participants were Black (n = 181) and White (n = 179) adults who were matched on age, self-reported sex, and level of education. Global sleep health was measured using the RU-SATED and dysfunctional beliefs about sleep were measured using the DBAS-16. Moderation analyses were conducted to investigate whether race moderated the association between DBAS-16 total and subscale scores and RU-SATED total scores.

Results: Race moderated the associations between DBAS-16 total score and subscale scores and RU-SATED total score (b = 0.54, p < .001). Higher DBAS-16 scores were significantly associated with lower RU-SATED scores in the white sample, while this association was not significant in the Black sample, except for the Sleep Expectations subscale, where the association was not significant in the White sample, and it was significant in the Black sample.

Conclusions: These findings highlight that the association between dysfunctional beliefs about sleep and global sleep health may systematically vary by race which may have implications for promoting sleep health equity in racial minority populations through clinical and advocacy work. Future studies are needed to investigate what specific factors may be impacting these unique associations.

目的:功能失调的睡眠观念与睡眠健康的组成部分有关,但它们与整体睡眠健康的关系却未得到充分研究。不同种族的人对睡眠的信念可能存在系统性差异,这可能会影响睡眠功能失调信念与整体睡眠健康之间的关联。本研究旨在调查种族是否会影响睡眠功能障碍信念与总体睡眠健康之间的关联:数据收集是在线调查的一部分。参与者为黑人(n = 181)和白人(n = 179)成年人,他们的年龄、自我报告的性别和受教育程度相匹配。使用 RU-SATED 测评总体睡眠健康状况,使用 DBAS-16 测评睡眠功能障碍信念。我们进行了调节分析,以研究种族是否调节了DBAS-16总分和分量表得分与RU-SATED总分之间的关联:结果:种族调节了 DBAS-16 总分和分量表得分与 RU-SATED 总分之间的关联(b = 0.54,p 结论:种族调节了 DBAS-16 总分和分量表得分与 RU-SATED 总分之间的关联:这些发现突出表明,睡眠功能障碍信念与总体睡眠健康之间的关联可能因种族而有系统性差异,这可能对通过临床和宣传工作促进少数种族人群的睡眠健康公平产生影响。今后还需要开展研究,以了解影响这些独特关联的具体因素。
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引用次数: 0
Values Expressed by Women Veterans Receiving Treatment for Chronic Insomnia Disorder. 接受慢性失眠治疗的女性退伍军人所表达的价值观。
IF 3.1 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-05-01 Epub Date: 2023-09-25 DOI: 10.1080/15402002.2023.2260517
Kathryn S Saldana, Gwendolyn C Carlson, Kaddy Revolorio, Monica R Kelly, Karen R Josephson, Michael N Mitchell, Najwa Culver, Morgan Kay, Sarah Kate McGowan, Yeonsu Song, Charles Deleeuw, Jennifer L Martin

Objectives: Insomnia may contribute to fewer value-consistent choices and less engagement in meaningful life activities. We sought to identify values commonly expressed by women veterans engaged in a trial testing psychological treatment of insomnia disorder.

Methods: Seventy-four women veterans (mean age = 48.3 [±13] years), meeting DSM-5 diagnostic criteria for insomnia disorder received an acceptance-based behavioral treatment for insomnia. In the first session, participants responded to questions regarding personal values and the impact of insomnia on those values. Responses were categorized into values domains informed by the Bull's Eye Values survey (level 1 categories) and the Valued Living Questionnaire (level 2 categories).

Results: Raters reached 100% agreement after independent coding and adjudication. Level 1 value categories in frequency order were: relationships (n = 68), personal care/health (n = 51), work/education (n = 46), pets (n = 12), and leisure (n = 5). The most frequently reported level 2 value categories were: family (other than marriage/parenting; n = 50), parenting (n = 31), work (n = 31), physical health (n = 30), and spirituality (n = 19). The level 1 value categories impacted by insomnia in frequency order were: personal care/health (n = 65), relationships (n = 58), work/education (n = 46), pets (n = 12), and leisure (n = 5).

Conclusions: Women veterans undergoing insomnia treatment highly value relationships and personal care/health, which should be considered patient-centered outcomes of insomnia treatments.

Clinical trials registration: NCT02076165.

目标:失眠可能导致价值观一致性选择减少,参与有意义的生活活动减少。我们试图确定参与失眠障碍心理治疗试验的女性退伍军人通常表达的价值观。方法:74名女性退伍军人(平均年龄 = 48.3[±13]岁),符合DSM-5失眠障碍诊断标准的患者接受了基于接受的失眠行为治疗。在第一节课上,参与者回答了有关个人价值观以及失眠对这些价值观的影响的问题。根据Bull's Eye价值观调查(1级类别)和有价值生活问卷(2级类别),将回答分为价值观领域。结果:评分者在独立编码和裁决后达成100%一致。按频率顺序排列的1级值类别为:关系(n = 68),个人护理/健康(n = 51),工作/教育(n = 46),宠物(n = 12) ,和休闲(n = 5) 。最常报告的2级价值类别是:家庭(婚姻/养育子女除外;n = 50),养育子女(n = 31),工作(n = 31),身体健康(n = 30)和精神(n = 19) 。受失眠影响的1级价值类别按频率顺序为:个人护理/健康(n = 65),关系(n = 58),工作/教育(n = 46),宠物(n = 12) ,和休闲(n = 5) 结论:接受失眠治疗的女性退伍军人高度重视人际关系和个人护理/健康,这应被视为失眠治疗的以患者为中心的结果。临床试验注册号:NCT02076165。
{"title":"Values Expressed by Women Veterans Receiving Treatment for Chronic Insomnia Disorder.","authors":"Kathryn S Saldana, Gwendolyn C Carlson, Kaddy Revolorio, Monica R Kelly, Karen R Josephson, Michael N Mitchell, Najwa Culver, Morgan Kay, Sarah Kate McGowan, Yeonsu Song, Charles Deleeuw, Jennifer L Martin","doi":"10.1080/15402002.2023.2260517","DOIUrl":"10.1080/15402002.2023.2260517","url":null,"abstract":"<p><strong>Objectives: </strong>Insomnia may contribute to fewer value-consistent choices and less engagement in meaningful life activities. We sought to identify values commonly expressed by women veterans engaged in a trial testing psychological treatment of insomnia disorder.</p><p><strong>Methods: </strong>Seventy-four women veterans (mean age = 48.3 [±13] years), meeting DSM-5 diagnostic criteria for insomnia disorder received an acceptance-based behavioral treatment for insomnia. In the first session, participants responded to questions regarding personal values and the impact of insomnia on those values. Responses were categorized into values domains informed by the Bull's Eye Values survey (level 1 categories) and the Valued Living Questionnaire (level 2 categories).</p><p><strong>Results: </strong>Raters reached 100% agreement after independent coding and adjudication. Level 1 value categories in frequency order were: relationships (<i>n</i> = 68), personal care/health (<i>n</i> = 51), work/education (<i>n</i> = 46), pets (<i>n</i> = 12), and leisure (<i>n</i> = 5). The most frequently reported level 2 value categories were: family (other than marriage/parenting; <i>n</i> = 50), parenting (<i>n</i> = 31), work (<i>n</i> = 31), physical health (<i>n</i> = 30), and spirituality (<i>n</i> = 19). The level 1 value categories impacted by insomnia in frequency order were: personal care/health (<i>n</i> = 65), relationships (<i>n</i> = 58), work/education (<i>n</i> = 46), pets (<i>n</i> = 12), and leisure (<i>n</i> = 5).</p><p><strong>Conclusions: </strong>Women veterans undergoing insomnia treatment highly value relationships and personal care/health, which should be considered patient-centered outcomes of insomnia treatments.</p><p><strong>Clinical trials registration: </strong>NCT02076165.</p>","PeriodicalId":55393,"journal":{"name":"Behavioral Sleep Medicine","volume":" ","pages":"340-352"},"PeriodicalIF":3.1,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10961253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41156840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal Sleep Health, Social Support, and Distress: A Mixed–Methods Analysis of Mothers of Infants and Young Children in Rural US 产妇睡眠健康、社会支持和压力:对美国农村婴幼儿母亲的混合方法分析
IF 3.1 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-04-11 DOI: 10.1080/15402002.2024.2339818
Alexandra R. Fischer, Kelly R. Doudell, Jenny M. Cundiff, Sha-Rhonda M. Green, Catherine A. Lavender, Heather E. Gunn
The purpose of this study was to explore sleep health in rural maternal populations through a social-ecological framework and identify risk and protective factors for this population.39 individuals...
本研究旨在通过社会生态框架探讨农村孕产妇的睡眠健康问题,并确定该人群的风险和保护因素。
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引用次数: 0
Mindful Night-to-Day: A Pilot Feasibility Trial of a Mindfulness-Based Insomnia and Symptom Management Intervention for Patients with Hematologic Cancer 夜以继日的正念:基于正念的血液肿瘤患者失眠和症状管理干预的试点可行性试验
IF 3.1 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-04-10 DOI: 10.1080/15402002.2024.2339819
Hannah M. Fisher, Kelly A. Hyland, Shannon N. Miller, Grace H. Amaden, Allison Diachina, Christi S. Ulmer, Meg Danforth, Thomas W. LeBlanc, Tamara J. Somers, Francis J. Keefe
Patients with hematologic cancer experience severe symptoms (i.e. insomnia, fatigue, pain, distress). Few interventions addressing insomnia and other symptoms exist for this population. Mindfulness...
血液肿瘤患者会出现严重的症状(如失眠、疲劳、疼痛、痛苦)。针对这一人群的失眠和其他症状的干预措施寥寥无几。正念...
{"title":"Mindful Night-to-Day: A Pilot Feasibility Trial of a Mindfulness-Based Insomnia and Symptom Management Intervention for Patients with Hematologic Cancer","authors":"Hannah M. Fisher, Kelly A. Hyland, Shannon N. Miller, Grace H. Amaden, Allison Diachina, Christi S. Ulmer, Meg Danforth, Thomas W. LeBlanc, Tamara J. Somers, Francis J. Keefe","doi":"10.1080/15402002.2024.2339819","DOIUrl":"https://doi.org/10.1080/15402002.2024.2339819","url":null,"abstract":"Patients with hematologic cancer experience severe symptoms (i.e. insomnia, fatigue, pain, distress). Few interventions addressing insomnia and other symptoms exist for this population. Mindfulness...","PeriodicalId":55393,"journal":{"name":"Behavioral Sleep Medicine","volume":"49 1","pages":""},"PeriodicalIF":3.1,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140589672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New parents’ sleep, movement, health, and well-being across the postpartum period 新父母在整个产后期间的睡眠、运动、健康和幸福感
IF 3.1 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-04-09 DOI: 10.1080/15402002.2024.2339815
Chelsea L. Kracht, Chris M. Blanchard, Danielle Symons Downs, Mark R. Beauchamp, Ryan E. Rhodes
The aim of this study was to examine changes and the bi-directional relationship in sleep and movement, and health and well-being among new parents and differences by sex.This secondary data analys...
本研究旨在探讨新手父母在睡眠与运动、健康与幸福方面的变化和双向关系,以及不同性别之间的差异。
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引用次数: 0
Affiliative Parent-Adolescent Bedtime and Waketime Interactions are Associated with Adolescent Sleep. 父母与青少年睡前和醒后的互动与青少年睡眠有关。
IF 2.2 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-03-03 Epub Date: 2023-06-15 DOI: 10.1080/15402002.2023.2217970
Emily L Ewing, Mengya Xia, Heather E Gunn

Objectives: The current study examined whether evening and morning affiliation (i.e., warmth) and autonomy (i.e., more or less in charge) around sleep routines predicted adolescent sleep on weekdays.

Method: Participants were 28 parent (Mage = 43.19; 85.17% mothers) and adolescent (Mage = 12.34 years) dyads who completed the same electronic diaries morning and evening for 10 days, with a total number of 221 nights observed across dyads. Sleep duration and sleep quality were assessed via the Pittsburgh Sleep Diary; degree of affiliation and autonomy around bedtime and waketime routines were assessed with single items on a visual analog scale. Multilevel modeling was utilized to evaluate the effects of more or less affiliation or autonomy on sleep outcomes (i.e., duration and quality) between and within dyads.

Results: Across all participants, adolescents who reported more affiliative interactions with their parent around bedtime and waketime slept longer and had better sleep quality at night. Further, when adolescents experienced greater than average affiliative interactions with their parent than was typical for them, they had better sleep quality that night. Adolescent sleep quality and duration were not impacted by whether or not adolescents were in charge of their bedtime and waketime routines.

Conclusions: Findings support parents' role in social and emotional security and highlight the importance of affiliative parent interactions around the sleep period for optimal sleep for young adolescents.

研究目的本研究探讨了晚间和早间睡眠常规的附属性(即温暖)和自主性(即更多或更少负责)是否会影响青少年平日的睡眠:方法:28 名父母(年龄=43.19;85.17% 为母亲)和青少年(年龄=12.34 岁)组成的双亲组合在 10 天内早晚填写了相同的电子日记,双亲组合共观察了 221 个夜晚。睡眠时间和睡眠质量通过匹兹堡睡眠日记进行评估;睡前和醒后作息的附属程度和自主程度通过视觉模拟量表的单个项目进行评估。我们利用多层次模型来评估在双亲之间和双亲内部,从属或自主程度的高低对睡眠结果(即睡眠时间和质量)的影响:结果:在所有参与者中,在就寝时间和醒来时间与父母有更多亲密互动的青少年睡眠时间更长,夜间睡眠质量更高。此外,当青少年与父母的亲情互动多于平均水平时,他们当晚的睡眠质量也会更好。青少年的睡眠质量和持续时间不受青少年是否负责自己的就寝和起床时间的影响:研究结果支持父母在社会和情感安全方面所扮演的角色,并强调了父母在青少年睡眠期间的亲情互动对其获得最佳睡眠的重要性。
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引用次数: 0
The Role of Cannabis and The Endocannabinoid System in Sleep Regulation and Cognition: A Review of Human and Animal Studies. 大麻和内源性大麻素系统在睡眠调节和认知中的作用:人类和动物研究综述
IF 2.2 3区 医学 Q3 CLINICAL NEUROLOGY Pub Date : 2024-03-03 Epub Date: 2023-07-03 DOI: 10.1080/15402002.2023.2232497
Alannah Miranda, Elizabeth Peek, Sonia Ancoli-Israel, Jared W Young, William Perry, Arpi Minassian

Objectives: Both sleep and cognition are partially modulated by the endocannabinoid (ECB) system. Cannabis has been reported to have effects on sleep and cognition. This review aims to summarize the recent literature on the ECB system, the role of cannabis and the ECB system on sleep regulation and cognition. Further, this review will identify existing gaps in knowledge and suggest potential targets for future research.

Methods: We performed this review in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Reports were identified by searching PubMed/MEDLINE, Embase, CINAHL, Web of Science, and PsycINFO for articles published through September 2021 for studies with data available on aspects of cognition, cannabis, or the ECB system, and sleep or circadian rhythms (CRs).

Results: We identified 6 human and 6 animal studies to be eligible for inclusion in this review. Several human studies found that cannabis use is not associated with changes in sleep quality or cognitive function. However, individual cannabinoids appeared to have independent effects on cognition and sleep; THC alone decreased cognitive performance and increased daytime sleepiness, whereas CBD alone had no effect on sleep or cognition. Animal studies demonstrated that manipulation of the ECB system altered activity and cognitive function, some of which appeared to be dependent on the light/dark cycle.

Conclusion: The sleep-wake cycle and CRs are both likely modulated by the ECB system, potentially resulting in effects on cognition, however this area is critically understudied.

研究目的睡眠和认知都受到内源性大麻素(ECB)系统的部分调节。据报道,大麻对睡眠和认知有影响。本综述旨在总结有关内源性大麻素系统、大麻和内源性大麻素系统对睡眠调节和认知的作用的最新文献。此外,本综述还将找出现有的知识空白,并提出未来研究的潜在目标:我们根据《系统综述和元分析首选报告项目》(PRISMA)指南进行了综述。我们检索了 PubMed/MEDLINE、Embase、CINAHL、Web of Science 和 PsycINFO 中截至 2021 年 9 月发表的文章,以确定是否有关于认知、大麻或 ECB 系统、睡眠或昼夜节律 (CRs) 等方面的研究报告:我们确定了 6 项人类研究和 6 项动物研究符合纳入本综述的条件。几项人类研究发现,吸食大麻与睡眠质量或认知功能的变化无关。不过,单个大麻素似乎对认知和睡眠有独立的影响;单是四氢大麻酚会降低认知能力并增加白天嗜睡,而单是大麻二酚则对睡眠或认知没有影响。动物研究表明,操纵ECB系统会改变活动和认知功能,其中一些似乎取决于光/暗周期:结论:睡眠-觉醒周期和CRs都可能受到ECB系统的调节,从而可能对认知产生影响,但这一领域的研究严重不足。
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引用次数: 0
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Behavioral Sleep Medicine
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