Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) is a new adjuvant therapy for the treatment of abdominal malignant tumors and metastases, which has shown great potential. The HIPEC technique can effectively kill residual lesions in the abdominal cavity through the synergistic sensitization effect of thermal chemotherapy and the circulating perfusion and washing effect of large volume perfusion fluid, thereby reducing the occurrence of malignant ascites and reducing the risk of postoperative recurrence and metastasis. However, there are still many problems in the practical operation of HIPEC, such as non-uniform distribution of perfusate temperature, inadequate perfusion due to the presence of 'dead space', incomplete cytoreductive surgery (CRS), instances of catheter obstruction during perfusate circulation, the lack of a uniform standard for selecting appropriate HIPEC techniques, occupational exposure of medical personnel during the HIPEC procedure, and the selection of HIPEC chemotherapy regimens for patients with various types of tumors. This article aims to summarize the problems encountered in the clinical practice of HIPEC, explore the problems that can be improved, and put forward some suggestions, so as to promote the further standardization and normalization of HIPEC technology.
{"title":"Hyperthermic intraperitoneal chemotherapy: Ideal and reality.","authors":"Fan-He Dong, Yu-Qiang Shan, Wen-Cheng Kong, Hao-Ran Wei, Lin-Po Zhou, Ye-Bin Yang, Jing Shi, Cheng-Hao Ji, Yi-Jia Zhang","doi":"10.1016/j.asjsur.2024.10.155","DOIUrl":"https://doi.org/10.1016/j.asjsur.2024.10.155","url":null,"abstract":"<p><p>Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) is a new adjuvant therapy for the treatment of abdominal malignant tumors and metastases, which has shown great potential. The HIPEC technique can effectively kill residual lesions in the abdominal cavity through the synergistic sensitization effect of thermal chemotherapy and the circulating perfusion and washing effect of large volume perfusion fluid, thereby reducing the occurrence of malignant ascites and reducing the risk of postoperative recurrence and metastasis. However, there are still many problems in the practical operation of HIPEC, such as non-uniform distribution of perfusate temperature, inadequate perfusion due to the presence of 'dead space', incomplete cytoreductive surgery (CRS), instances of catheter obstruction during perfusate circulation, the lack of a uniform standard for selecting appropriate HIPEC techniques, occupational exposure of medical personnel during the HIPEC procedure, and the selection of HIPEC chemotherapy regimens for patients with various types of tumors. This article aims to summarize the problems encountered in the clinical practice of HIPEC, explore the problems that can be improved, and put forward some suggestions, so as to promote the further standardization and normalization of HIPEC technology.</p>","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Current trends in small intestinal adenocarcinoma: An epidemiological survey, genetic mutation profile, and drug sensitivity analysis.","authors":"Yongqi Dong, Rongqiong Jiang, Bennan Zhao, Shengsheng Xu","doi":"10.1016/j.asjsur.2024.10.225","DOIUrl":"10.1016/j.asjsur.2024.10.225","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-18DOI: 10.1016/j.asjsur.2024.10.194
Qing Li, Guanglong Hao, Rui Su, Yuelin Zhou
{"title":"The quality of life of myopic students treated with different vision correction methods: A Chinese college survey.","authors":"Qing Li, Guanglong Hao, Rui Su, Yuelin Zhou","doi":"10.1016/j.asjsur.2024.10.194","DOIUrl":"https://doi.org/10.1016/j.asjsur.2024.10.194","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-18DOI: 10.1016/j.asjsur.2024.10.070
Yi Xue, Yongzhong Zhao, Baolong Dong, Xiaojun Yang
{"title":"Complete pathological response in a patient with locally advanced rectal cancer following conversion therapy: A case report.","authors":"Yi Xue, Yongzhong Zhao, Baolong Dong, Xiaojun Yang","doi":"10.1016/j.asjsur.2024.10.070","DOIUrl":"https://doi.org/10.1016/j.asjsur.2024.10.070","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-18DOI: 10.1016/j.asjsur.2024.10.203
Chao Zhu, Yong Wang, Qing Pang, Hao Jin
{"title":"Primary hepatic schwannoma in a patient with metabolic dysfunction-associated steatotic liver disease (MASLD): A case report.","authors":"Chao Zhu, Yong Wang, Qing Pang, Hao Jin","doi":"10.1016/j.asjsur.2024.10.203","DOIUrl":"https://doi.org/10.1016/j.asjsur.2024.10.203","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-18DOI: 10.1016/j.asjsur.2024.10.257
Pei-Jie Li, Ya-Fei Cao, Fei Tan, Sheng-Hu Zhou
{"title":"Total hip arthroplasty for postoperative internal fixation loosening with bone nonunion of intertrochanteric fractures: A case report.","authors":"Pei-Jie Li, Ya-Fei Cao, Fei Tan, Sheng-Hu Zhou","doi":"10.1016/j.asjsur.2024.10.257","DOIUrl":"https://doi.org/10.1016/j.asjsur.2024.10.257","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-18DOI: 10.1016/j.asjsur.2024.10.259
LiHua Liu, Jia Yang, YeShu Sun, Ji Zhang
{"title":"\"Hand as Foot\" teaching model in non-palpable breast tumors.","authors":"LiHua Liu, Jia Yang, YeShu Sun, Ji Zhang","doi":"10.1016/j.asjsur.2024.10.259","DOIUrl":"https://doi.org/10.1016/j.asjsur.2024.10.259","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-18DOI: 10.1016/j.asjsur.2024.10.158
Jiangfeng Shen, Peng Zhang, Fei Wang, Fei Sun
{"title":"Clinical pathological features of mediastinal spindle cell sarcoma: A case report and literature review.","authors":"Jiangfeng Shen, Peng Zhang, Fei Wang, Fei Sun","doi":"10.1016/j.asjsur.2024.10.158","DOIUrl":"https://doi.org/10.1016/j.asjsur.2024.10.158","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-18DOI: 10.1016/j.asjsur.2024.10.157
Jiajin Liu, Aifeng Liu, Longyao Zhang, Chao Zhang
{"title":"Unique charm of Chinese medicine: Conservative treatment resulted in reabsorption of a large herniated disc.","authors":"Jiajin Liu, Aifeng Liu, Longyao Zhang, Chao Zhang","doi":"10.1016/j.asjsur.2024.10.157","DOIUrl":"https://doi.org/10.1016/j.asjsur.2024.10.157","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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