Asian Journal of Surgery最新文献

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ZIC2 demonstrates potential as a diagnostic and prognostic biomarker in hepatocellular carcinoma ZIC2显示了作为肝细胞癌诊断和预后生物标志物的潜力

IF 3.8 3区医学 Q1 SURGERY

Asian Journal of Surgery

Pub Date : 2026-02-01 DOI: 10.1016/j.asjsur.2025.07.252

Caixia Zhao , Xia Fan , Wei Zhang , Peng Liu

引用次数: 0

Hepatoprotective effects of potassium magnesium aspartate in patients undergoing hepatectomy for hepatocellular carcinoma: A retrospective cohort study 天冬氨酸钾镁对肝细胞癌肝切除术患者的肝保护作用：一项回顾性队列研究

IF 3.8 3区医学 Q1 SURGERY

Asian Journal of Surgery

Pub Date : 2026-02-01 DOI: 10.1016/j.asjsur.2025.07.281

Zi-yu Wang , Man Rong , Qing-an Wang , Bin Liu

引用次数: 0

Risk factors of clustered compression vertebral refractures after percutaneous vertebral augmentation 经皮椎体隆胸术后聚集性压缩性椎体再骨折的危险因素

IF 3.8 3区医学 Q1 SURGERY

Asian Journal of Surgery

Pub Date : 2026-02-01 DOI: 10.1016/j.asjsur.2025.08.198

Si Chen, Li Huo, Wenjie Wu

引用次数: 0

Personalized nursing plan based on accelerated rehabilitation for the prevention of deep vein thrombosis 基于加速康复的个性化护理方案预防深静脉血栓形成

IF 3.8 3区医学 Q1 SURGERY

Asian Journal of Surgery

Pub Date : 2026-02-01 DOI: 10.1016/j.asjsur.2025.08.134

Jiayong Huang , Lirong Guo , Cuifang Lin, Jiahong Guo

引用次数: 0

Combined hepatocellular carcinoma-cholangiocarcinoma with sarcomatoid differentiation: A case report 肝细胞癌-胆管癌合并肉瘤样分化1例

IF 3.8 3区医学 Q1 SURGERY

Asian Journal of Surgery

Pub Date : 2026-02-01 DOI: 10.1016/j.asjsur.2025.07.199

Yudong Zhan , Jiao Guo , Yiming Han , Jie Zheng

引用次数: 0

ATG7 is associated with immune infiltration and affects the prognosis of colorectal cancer patients ATG7与免疫浸润有关，影响结直肠癌患者预后

IF 3.8 3区医学 Q1 SURGERY

Asian Journal of Surgery

Pub Date : 2026-02-01 DOI: 10.1016/j.asjsur.2025.08.234

Mei-zhen Zhu , Hong Chen , Di-wen Shi , Li-qiang Zhu, Ting-feng He, Fei Xu, Hai-jian Sun, Li-ying Qiu, Yue-tao Zhou

Purpose

With immunotherapy for colorectal cancer (COAD or CRC) presenting certain adverse effects, there arises a pressing need for novel targets within this domain. Hence, this study endeavors to explore the potential role of ATG7, an immune autophagy gene, as a pivotal factor influencing tumor cell growth.

Methods

The mRNA expression profile of ATG7 was assessed by aggregating samples from both tumor and normal tissues sourced from the TCGA, TARGET, and GTEx databases. The HPA database and GEPIA database were used to examine the expression and location of ATG7 in tumor tissues and its correlation with the survival rate of tumor patients. In addition, we used the STRING, TIMER 2.0 and LinkedOmics database to analyze the role of ATG7 in immune-related signaling pathways.

Results

This study demonstrated that ATG7 expression was significantly elevated in tumor tissues compared to normal tissues. Furthermore, higher ATG7 expression was associated with a more favorable prognosis in colorectal cancer (COAD). Additionally, our analysis revealed notable correlations between ATG7 expression in COAD and immune cell infiltration and immune cell markers, with ATG7 having the highest correlation with STAT1. Finally, the examination of the co-expression network of ATG7 revealed its involvement in the humoral immune response, response to interleukin-12, and activation of granulocytes.

Conclusion

The findings of this study highlight the pivotal role of ATG7 in multiple signaling pathways associated with immune response, immune cell infiltration, and tumor regulation. Therefore, ATG7 could be a promising biomarker for assessing the prognosis of patients with COAD.

目的：随着结直肠癌（COAD或CRC）的免疫治疗出现一定的不良反应，迫切需要在该领域寻找新的靶点。因此，本研究试图探索免疫自噬基因ATG7作为影响肿瘤细胞生长的关键因素的潜在作用。方法通过收集来自TCGA、TARGET和GTEx数据库的肿瘤和正常组织样本，评估ATG7 mRNA表达谱。利用HPA数据库和GEPIA数据库检测ATG7在肿瘤组织中的表达、定位及其与肿瘤患者生存率的相关性。此外，我们利用STRING、TIMER 2.0和LinkedOmics数据库分析了ATG7在免疫相关信号通路中的作用。结果ATG7在肿瘤组织中的表达明显高于正常组织。此外，较高的ATG7表达与结直肠癌（COAD）更有利的预后相关。此外，我们的分析显示，ATG7在COAD中的表达与免疫细胞浸润和免疫细胞标志物之间存在显著相关性，其中ATG7与STAT1的相关性最高。最后，对ATG7共表达网络的检测显示其参与体液免疫反应、对白细胞介素-12的反应和粒细胞的活化。结论ATG7在免疫应答、免疫细胞浸润、肿瘤调控等多种信号通路中发挥着重要作用。因此，ATG7可能是评估COAD患者预后的一个有前景的生物标志物。

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引用次数: 0

Pericapsular Nerve Group (PENG) block versus supra-inguinal fascia iliaca compartment block (S-FICB) for hip surgery: A systematic review and meta-analysis 髋关节手术的囊周神经阻滞（PENG）与腹股沟上筋膜髂隔室阻滞（S-FICB）：一项系统回顾和荟萃分析

IF 3.8 3区医学 Q1 SURGERY

Asian Journal of Surgery

Pub Date : 2026-02-01 DOI: 10.1016/j.asjsur.2025.08.274

Jinhui Yao , Yan Yang , Yi Qiu , Nari Wulan

This systematic review and meta-analysis evaluating 359 patients across five randomized controlled trials compared the supra-inguinal fascia iliaca compartment block (S-FICB) and pericapsular nerve group (PENG) block for hip surgery analgesia, revealing nuanced clinical distinctions. While both techniques demonstrated equivalent efficacy in static pain management (6–24 h postoperatively) and 24-h opioid consumption (P > 0.05), the PENG block emerged as superior for dynamic pain control, with significantly lower pain scores at 12 h (MD = −1.17, 95 % CI: −1.92 to −0.42), 24 h (MD = −1.23, −1.82 to −0.65), and 48 h (MD = −1.19, −1.71 to −0.66) post-surgery (all P < 0.01). Notably, the PENG group achieved earlier ambulation (19.6 vs. 26.5 h, P < 0.01) and exhibited markedly lower quadriceps motor blockade incidence (45 % vs. 90 %, P < 0.001), underscoring its motor-sparing advantage. These findings position the PENG block as a preferential option within Enhanced Recovery After Surgery (ERAS) protocols, particularly benefiting patients requiring early mobility, despite comparable static analgesia and postoperative nausea/vomiting rates between groups. The study highlights the clinical significance of selective sensory targeting in optimizing functional recovery while advocating for further high-quality research to standardize techniques and assess long-term outcomes.

这项系统综述和荟萃分析评估了5项随机对照试验中的359例患者，比较了腹腹沟上筋膜髂腔阻滞（S-FICB）和囊周神经组（PENG）阻滞在髋关节手术镇痛中的作用，揭示了细微的临床差异。虽然这两种技术在静态疼痛管理（术后6-24小时）和24小时阿片类药物消耗（P > 0.05）方面表现出相同的疗效，但彭阻滞在动态疼痛控制方面表现优异，在术后12小时（MD = - 1.17, 95% CI: - 1.92至- 0.42），24小时（MD = - 1.23, - 1.82至- 0.65）和48小时（MD = - 1.19, - 1.71至- 0.66）疼痛评分明显较低（均P <； 0.01）。值得注意的是，PENG组实现了更早的活动（19.6对26.5小时，P < 0.01），并表现出明显较低的股四头肌运动阻滞发生率（45%对90%，P < 0.001），强调了其运动节约优势。这些研究结果表明，尽管两组之间的静态镇痛和术后恶心/呕吐率相当，但彭阻滞在增强术后恢复（ERAS）方案中是优先选择，特别是对需要早期活动的患者有益。该研究强调了选择性感觉靶向在优化功能恢复方面的临床意义，同时提倡进一步的高质量研究，以标准化技术和评估长期结果。

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引用次数: 0

Hip preservation therapy for diffuse large B-cell lymphoma: A case report 髋关节保留治疗弥漫性大b细胞淋巴瘤1例报告

IF 3.8 3区医学 Q1 SURGERY

Asian Journal of Surgery

Pub Date : 2026-02-01 DOI: 10.1016/j.asjsur.2025.07.179

Haoxing Li , Lichao Deng , Xiaobo Niu, Changhai Wang

引用次数: 0

Analysis of risk factors for atrial high-rate episodes in patients with permanent pacemakers: Impact of rapid atrial rate burden and development of the RePS prediction model 永久性起搏器患者心房高率发作的危险因素分析：快速心房率负担的影响及RePS预测模型的建立

IF 3.8 3区医学 Q1 SURGERY

Asian Journal of Surgery

Pub Date : 2026-02-01 DOI: 10.1016/j.asjsur.2025.07.169

Wei Feng , Ning Zhang , Wenlong Wang , Feifei Wang

引用次数: 0

Eosinophilic hepatic infiltration following travel-related parasite infestation 旅行相关寄生虫感染后嗜酸性肝脏浸润

IF 3.8 3区医学 Q1 SURGERY

Asian Journal of Surgery

Pub Date : 2026-02-01 DOI: 10.1016/j.asjsur.2025.07.188

Xueqi Sun , Binglin Lai

引用次数: 0

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