Background: Adjuvant chemotherapy is a standard therapeutic option for resected pancreatic cancer. However, the risk factors for incompletion of adjuvant chemotherapy remain unclear.
Methods: We retrospectively reviewed the medical records of 72 patients who underwent radical pancreatectomy and received S-1 adjuvant chemotherapy for pancreatic cancer. The patients were assigned to two groups according to their completion or incompletion of adjuvant chemotherapy. We compared the perioperative skeletal muscle mass index (SMI) and nutritional status using prognostic nutritional index (PNI) between the two groups.
Results: The completion and incompletion groups included 46 (64 %) and 26 (36 %) patients, respectively. Overall survival was shorter in the incompletion group than in the completion group (median survival time, 20.2 months vs. 42.0 months; log-rank, p = 0.018). Decreasing rate of PNI (12.7 % vs. 0.2 %, p = 0.010) and decreasing rate of SMI (26.9 % vs. 12.5 %, p = 0.001) were significantly larger in the incompletion group than in the completion group. Multivariate analysis showed that decreasing rate of PNI (p = 0.016), decreasing rate of SMI (p = 0.013), and old age (p = 0.049) were independent risk factors for incompletion of S-1 adjuvant chemotherapy. Regarding the time-series variations, PNI improved from 1 to 3 months after pancreatectomy in the completion group (p = 0.006). Furthermore, the decreasing slope of SMI was stronger in the incompletion group.
Conclusion: Postoperative decrease of PNI and SMI is associated with the incompletion of S-1 adjuvant chemotherapy.
{"title":"Clinical impact of the prognostic nutritional index and skeletal muscle index for the incompletion of adjuvant chemotherapy for pancreatic cancer.","authors":"Hiromitsu Maehira, Haruki Mori, Nobuhito Nitta, Takeru Maekawa, Yusuke Nishina, Hajime Ishikawa, Katsushi Takebayashi, Sachiko Kaida, Toru Miyake, Masaji Tani","doi":"10.1016/j.asjsur.2024.10.151","DOIUrl":"https://doi.org/10.1016/j.asjsur.2024.10.151","url":null,"abstract":"<p><strong>Background: </strong>Adjuvant chemotherapy is a standard therapeutic option for resected pancreatic cancer. However, the risk factors for incompletion of adjuvant chemotherapy remain unclear.</p><p><strong>Methods: </strong>We retrospectively reviewed the medical records of 72 patients who underwent radical pancreatectomy and received S-1 adjuvant chemotherapy for pancreatic cancer. The patients were assigned to two groups according to their completion or incompletion of adjuvant chemotherapy. We compared the perioperative skeletal muscle mass index (SMI) and nutritional status using prognostic nutritional index (PNI) between the two groups.</p><p><strong>Results: </strong>The completion and incompletion groups included 46 (64 %) and 26 (36 %) patients, respectively. Overall survival was shorter in the incompletion group than in the completion group (median survival time, 20.2 months vs. 42.0 months; log-rank, p = 0.018). Decreasing rate of PNI (12.7 % vs. 0.2 %, p = 0.010) and decreasing rate of SMI (26.9 % vs. 12.5 %, p = 0.001) were significantly larger in the incompletion group than in the completion group. Multivariate analysis showed that decreasing rate of PNI (p = 0.016), decreasing rate of SMI (p = 0.013), and old age (p = 0.049) were independent risk factors for incompletion of S-1 adjuvant chemotherapy. Regarding the time-series variations, PNI improved from 1 to 3 months after pancreatectomy in the completion group (p = 0.006). Furthermore, the decreasing slope of SMI was stronger in the incompletion group.</p><p><strong>Conclusion: </strong>Postoperative decrease of PNI and SMI is associated with the incompletion of S-1 adjuvant chemotherapy.</p>","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-12DOI: 10.1016/j.asjsur.2024.10.110
Changpeng Wu, Bo Yang, Shaojun Yang, Zheng Liu
{"title":"A case report of delayed contralateral subdural hematoma after neuroendoscopic minimally invasive hematoma evacuation for nontraumatic intracerebral hemorrhage.","authors":"Changpeng Wu, Bo Yang, Shaojun Yang, Zheng Liu","doi":"10.1016/j.asjsur.2024.10.110","DOIUrl":"https://doi.org/10.1016/j.asjsur.2024.10.110","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-12DOI: 10.1016/j.asjsur.2024.10.181
Zhen Cheng, Linzhong Chen, Xiaofang Dong
{"title":"Long-term response to first-line treatment with sintilimab plus chemotherapy in a patient with advanced lung squamous cell carcinoma: A case report.","authors":"Zhen Cheng, Linzhong Chen, Xiaofang Dong","doi":"10.1016/j.asjsur.2024.10.181","DOIUrl":"https://doi.org/10.1016/j.asjsur.2024.10.181","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Axillary Osmidrosis is highly prevalent and occurr in adolescents, bilateral onset, its pathogenesis is related to abnormal secretion function of apocrine glands, with a significant genetic predisposition, the patient's bilateral armpit area can smell a spicy pungent odor, although it does not affect the health, but it is inconvenient to life, socialize. Patients are often accompanied by low self-esteem and urgently require treatment, and most of them have the requirement of minimally invasive treatment and minimal scarring.
Method: In this study, we aimed to evaluate the efficacy of minimally invasive treatment of axillary osmidrosis with refined negative pressure-assisted rubbing suction technique. From August 2022 to August 2023, 50 patients (28 females and 22 males) with axillary osmidrosis were treated with refined negative pressure-assisted rubbing suction technique. HE staining of the tissue rubbed out of six of these patients showed a large amount of apocrine gland.
Results: In the subjective evaluation of 50 (100 sides) patients, 66 sides (66 %) were very satisfied with the results of the treatment, 30 sides (30 %) were satisfied, and 4 sides (4 %) were dissatisfied. Clinical efficacy evaluation showed that 74 sides (74 %) of patients rated the results as cured, 18 sides (18 %) as significantly effective, 4 sides (4 %) as effective, and 4 sides (4 %) as ineffective. No serious surgical complications occurred except for the occurrence of Subcutaneous hydrops and hematoma on 6 sides.
Conclusions: Refined negative pressure-assisted rubbing suction technique is an easy and effective method for minimally invasive treatment of axillary hyperhidrosis and deserves clinical promotion.
{"title":"Negative pressure assisted rubbing suction technique for the treatment of axillary osmidrosis based on minimally invasive principle.","authors":"Shuhao Xu, Yucang Shi, Xiaofang Li, Ping Yao, Qianqian Zhang, Jiajie Xian, Ke Liu, Simu Liao, Zeyong Wu","doi":"10.1016/j.asjsur.2024.10.146","DOIUrl":"https://doi.org/10.1016/j.asjsur.2024.10.146","url":null,"abstract":"<p><strong>Background: </strong>Axillary Osmidrosis is highly prevalent and occurr in adolescents, bilateral onset, its pathogenesis is related to abnormal secretion function of apocrine glands, with a significant genetic predisposition, the patient's bilateral armpit area can smell a spicy pungent odor, although it does not affect the health, but it is inconvenient to life, socialize. Patients are often accompanied by low self-esteem and urgently require treatment, and most of them have the requirement of minimally invasive treatment and minimal scarring.</p><p><strong>Method: </strong>In this study, we aimed to evaluate the efficacy of minimally invasive treatment of axillary osmidrosis with refined negative pressure-assisted rubbing suction technique. From August 2022 to August 2023, 50 patients (28 females and 22 males) with axillary osmidrosis were treated with refined negative pressure-assisted rubbing suction technique. HE staining of the tissue rubbed out of six of these patients showed a large amount of apocrine gland.</p><p><strong>Results: </strong>In the subjective evaluation of 50 (100 sides) patients, 66 sides (66 %) were very satisfied with the results of the treatment, 30 sides (30 %) were satisfied, and 4 sides (4 %) were dissatisfied. Clinical efficacy evaluation showed that 74 sides (74 %) of patients rated the results as cured, 18 sides (18 %) as significantly effective, 4 sides (4 %) as effective, and 4 sides (4 %) as ineffective. No serious surgical complications occurred except for the occurrence of Subcutaneous hydrops and hematoma on 6 sides.</p><p><strong>Conclusions: </strong>Refined negative pressure-assisted rubbing suction technique is an easy and effective method for minimally invasive treatment of axillary hyperhidrosis and deserves clinical promotion.</p>","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-11DOI: 10.1016/j.asjsur.2024.10.180
Zeyang Li, Shenqi Lu, Tao Su, Chengxin Guo
{"title":"The causal association between lipidome and ankylosing spondylitis: A Mendelian randomization analysis.","authors":"Zeyang Li, Shenqi Lu, Tao Su, Chengxin Guo","doi":"10.1016/j.asjsur.2024.10.180","DOIUrl":"https://doi.org/10.1016/j.asjsur.2024.10.180","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-11DOI: 10.1016/j.asjsur.2024.10.087
Xiaohong Cui, Xiaoyan Yu, Yanyan Wang, Fangying Li
{"title":"Comprehensive analysis to evaluate the effectiveness of interventions such as exercise, nutrition, and medication on muscle mass and function in elderly patients with sarcopenia: A meta-analysis.","authors":"Xiaohong Cui, Xiaoyan Yu, Yanyan Wang, Fangying Li","doi":"10.1016/j.asjsur.2024.10.087","DOIUrl":"https://doi.org/10.1016/j.asjsur.2024.10.087","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-11DOI: 10.1016/j.asjsur.2024.10.125
Ming Liang, Peng Yu, Wenwen Li, Jie Liu
{"title":"Intraductal oncocytic papillary neoplasms of the pancreas: A rare case.","authors":"Ming Liang, Peng Yu, Wenwen Li, Jie Liu","doi":"10.1016/j.asjsur.2024.10.125","DOIUrl":"https://doi.org/10.1016/j.asjsur.2024.10.125","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-11DOI: 10.1016/j.asjsur.2024.10.165
Huaneng Wen, Shaoyang Cui, Mingzhu Xu
{"title":"Mechanism of apitherapy in preventing and treating Alzheimer's disease: A bibliometric analysis.","authors":"Huaneng Wen, Shaoyang Cui, Mingzhu Xu","doi":"10.1016/j.asjsur.2024.10.165","DOIUrl":"https://doi.org/10.1016/j.asjsur.2024.10.165","url":null,"abstract":"","PeriodicalId":55454,"journal":{"name":"Asian Journal of Surgery","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142633735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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