Archives of Cardiovascular Diseases最新文献

英文中文

Thoughts on the European Society of Cardiology 2024 guidelines for the management of elevated blood pressure and hypertension

IF 2.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Archives of Cardiovascular Diseases

Pub Date : 2025-04-01 DOI: 10.1016/j.acvd.2025.02.002

Jacques Blacher , Valérie Olié , Laurence Amar , François Dievart , Béatrice Duly-Bouhanick

引用次数: 0

Response to a letter from Tomoyuki Kawada commenting on the article entitled “Sex-specific predictive factors of smoking cessation in subjects at high cardiovascular risk”

IF 2.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Archives of Cardiovascular Diseases

Pub Date : 2025-04-01 DOI: 10.1016/j.acvd.2024.12.015

Ingrid Allagbé , Marianne Zeller , Daniel Thomas , Guillaume Airagnes , Frédéric Limosin , Abdelali Boussadi , Frédéric Chagué , Anne-Laurence Le Faou

引用次数: 0

Left atrial appendage function after conversion to sinus rhythm in patients with sepsis-induced atrial fibrillation

IF 2.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Archives of Cardiovascular Diseases

Pub Date : 2025-04-01 DOI: 10.1016/j.acvd.2024.12.014

Vincent Labbé , Stephane Ederhy , David Legouis , Jérémie Joffre , François Bagate , Oumar Sy , Frank Chemouni , Armand Mekontso Dessap , Muriel Fartoukh , Ariel Cohen , the FAST study group

引用次数: 0

Transcatheter aortic valve implantation: Association between skin flora and infective endocarditis?

IF 2.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Archives of Cardiovascular Diseases

Pub Date : 2025-04-01 DOI: 10.1016/j.acvd.2024.12.007

Julie Lourtet-Hascoët , Jerome Van Rothem , Nicolas Combes , Benjamin Honton , Sébastien Hascoët , Jean-Louis Galinier , Benoit Fontenel , Hélène Charbonneau , Eric Bonnet

Background

Infective endocarditis is a rare but severe complication that may arise following transcatheter aortic valve implantation. Recent advances in microbiological epidemiology have highlighted staphylococci and enterococci as the primary pathogens involved.

Aim

To investigate the prevalence of these bacteria in patients’ cutaneous flora before and after transcatheter aortic valve implantation procedures, and to assess the implications for antibiotic prophylaxis recommendations.

Methods

A single-centre prospective epidemiological study was conducted, enrolling patients admitted consecutively for transcatheter aortic valve implantation procedures between June 2021 and February 2022. Cutaneous samples were obtained from each patient at the puncture site of the transcatheter aortic valve implantation procedure, before and after skin detersion, and from operator hands after skin detersion.

Results

One hundred patients were included, with a mean age of 82 ± 6.1 years, a male-to-female ratio of 0.48 and a mean body mass index of 29 ± 4.4 kg/m². Before skin detersion, cutaneous samples were positive in 58 patients; among them were coagulase-negative staphylococci (n = 48, 82%, 95% confidence interval 71–91%), enterococci (n = 12, 21%, 95% confidence interval: 11–33%), Staphylococcus aureus (n = 2, 3%, 95% confidence interval 0–12%) and Enterobacteriaceae (n = 4, 7%, 95% confidence interval: 2–17%).

Conclusions

Enterococci are frequently present in patients’ cutaneous flora at the puncture site before skin detersion, suggesting a potential source for infective endocarditis after transcatheter aortic valve implantation. These findings support considering amoxicillin-clavulanate as antibiotic prophylaxis before transcatheter aortic valve implantation procedures to mitigate the risk of infective endocarditis associated with enterococcal colonization.

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引用次数: 0

Early and late bleeding events according to Valve Academic Research Consortium 3 criteria following transcatheter aortic valve implantation

IF 2.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Archives of Cardiovascular Diseases

Pub Date : 2025-04-01 DOI: 10.1016/j.acvd.2024.12.009

Maxime Nolf , Dominique Boulmier , Guillaume Leurent , Jacques Tomasi , Florent Le Bars , Abdelkader Bakhti , Sam Sharobeem , Léo Lemarchand , Gwenaelle Sost , Marielle Le Guellec , Hervé Le Breton , Vincent Auffret

Background

Transcatheter aortic valve implantation may be associated with significant haemorrhagic complications.

Aims

To evaluate the timing, incidence, predictors and clinical impact of bleeding events after transcatheter aortic valve implantation, according to the updated Valve Academic Research Consortium (VARC)-3 criteria, compared with the VARC-2 criteria.

Methods

A retrospective observational study involving 487 consecutive patients who underwent transcatheter aortic valve implantation between July 2017 and May 2019 was performed. Bleeding events were classified according to the VARC-2 and VARC-3 definitions.

Results

Bleeding events occurred in 17.6% of patients, with early bleeding (in-hospital) in 12.5% and late bleeding (occurring after discharge) in 6.1%. The primary vascular access site was the most common source of early bleeding, whereas gastrointestinal bleeding was predominant in late events. Significant predictors of early VARC-3-defined bleeding included active cancer, previous implantable cardioverter-defibrillator, history of mitral valve surgery, a non-transfemoral approach and occurrence of an in-hospital major vascular complication or new-onset atrial fibrillation. Late bleeding was independently associated with a history of myocardial infarction and treatment with vitamin K antagonists at discharge. Early bleeding events were not associated with increased late all-cause mortality. No significant difference was observed based on the VARC-2 and VARC-3 bleeding definitions.

Conclusions

Bleeding events occurred in one sixth of patients undergoing transcatheter aortic valve implantation without significant difference in their incidence between the VARC-2 and VARC-3 classifications. Early bleeding events were not associated with poorer long-term survival, regardless of the classification used. Larger studies with greater statistical power, including more contemporary patients, are needed to confirm these findings.

{"title":"Early and late bleeding events according to Valve Academic Research Consortium 3 criteria following transcatheter aortic valve implantation","authors":"Maxime Nolf , Dominique Boulmier , Guillaume Leurent , Jacques Tomasi , Florent Le Bars , Abdelkader Bakhti , Sam Sharobeem , Léo Lemarchand , Gwenaelle Sost , Marielle Le Guellec , Hervé Le Breton , Vincent Auffret","doi":"10.1016/j.acvd.2024.12.009","DOIUrl":"10.1016/j.acvd.2024.12.009","url":null,"abstract":"<div><h3>Background</h3><div>Transcatheter aortic valve implantation may be associated with significant haemorrhagic complications.</div></div><div><h3>Aims</h3><div>To evaluate the timing, incidence, predictors and clinical impact of bleeding events after transcatheter aortic valve implantation, according to the updated Valve Academic Research Consortium (VARC)-3 criteria, compared with the VARC-2 criteria.</div></div><div><h3>Methods</h3><div>A retrospective observational study involving 487 consecutive patients who underwent transcatheter aortic valve implantation between July 2017 and May 2019 was performed. Bleeding events were classified according to the VARC-2 and VARC-3 definitions.</div></div><div><h3>Results</h3><div>Bleeding events occurred in 17.6% of patients, with early bleeding (in-hospital) in 12.5% and late bleeding (occurring after discharge) in 6.1%. The primary vascular access site was the most common source of early bleeding, whereas gastrointestinal bleeding was predominant in late events. Significant predictors of early VARC-3-defined bleeding included active cancer, previous implantable cardioverter-defibrillator, history of mitral valve surgery, a non-transfemoral approach and occurrence of an in-hospital major vascular complication or new-onset atrial fibrillation. Late bleeding was independently associated with a history of myocardial infarction and treatment with vitamin K antagonists at discharge. Early bleeding events were not associated with increased late all-cause mortality. No significant difference was observed based on the VARC-2 and VARC-3 bleeding definitions.</div></div><div><h3>Conclusions</h3><div>Bleeding events occurred in one sixth of patients undergoing transcatheter aortic valve implantation without significant difference in their incidence between the VARC-2 and VARC-3 classifications. Early bleeding events were not associated with poorer long-term survival, regardless of the classification used. Larger studies with greater statistical power, including more contemporary patients, are needed to confirm these findings.</div></div>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"118 4","pages":"Pages 248-259"},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Changes in microcirculation following transcatheter aortic valve implantation in patients with stable coronary artery disease 稳定型冠心病患者经导管主动脉瓣植入术后微循环的变化。

IF 2.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Archives of Cardiovascular Diseases

Pub Date : 2025-04-01 DOI: 10.1016/j.acvd.2024.12.006

Quentin Battistolo , Robin Le Ruz , Pierre-Guillaume Piriou , Patrice Guerin , Vincent Letocart , Julien Plessis , Alexandra Poinas , Thomas Senage , Thibaut Manigold

Background

Few studies have assessed coronary physiology in the setting of coronary artery disease (CAD) with severe aortic stenosis (AS). Fractional flow reserve (FFR) to guide revascularization in such patients is not validated.

Aims

We describe changes in coronary physiology in this population before and after transcatheter aortic valve implantation (TAVI).

Methods

Patients with stable CAD and severe AS treated with TAVI were prospectively included during 2020–2023. Coronary physiology was assessed before and immediately after TAVI, and at follow-up (median 5.4 months).

Results

Twenty-nine patients (mean age 81.3 years) were included. Median (95% confidence interval) FFR decreased numerically, from 0.83 (0.79–0.84) pre-TAVI to 0.81 (0.78–0.83) post-TAVI. During hyperaemia, the transit mean time reduced numerically, from 0.27 (0.19–0.35) to 0.20 (0.18–0.27) seconds, reflecting increased coronary flow. Basal microvascular resistance increased numerically, from 24 (21–35) to 32 (23–45), while resistive reserve ratio increased significantly, from 1.8 (1.5–2.3) to 2.6 (2.2–3.1) (P = 0.002). Consequently, coronary flow reserve (CFR) improved significantly, from 1.5 (1.2–1.7) to 1.9 (1.5–2.4) (P = 0.006). Among 21 patients with follow-up, no significant change in FFR was observed and the significance of the increase in CFR was lost. Only three patients had an index of microvascular resistance > 25, indicating microvascular impairment during hyperaemia.

Conclusions

In stable CAD patients treated with TAVI for severe AS, valve replacement provides an immediate improvement in CFR. FFR shows a minimal decrease after valve implantation, supporting its reproducibility to guide revascularization in such patients.

Clinical trial registration

. NCT04663334.

背景：很少有研究评估冠状动脉疾病（CAD）合并严重主动脉瓣狭窄（AS）的冠状动脉生理学。分数血流储备（FFR）指导此类患者血运重建的方法尚未得到证实。目的：我们描述了在经导管主动脉瓣植入术（TAVI）前后这一人群冠状动脉生理学的变化。方法：前瞻性纳入2020-2023年经TAVI治疗的稳定型CAD和严重AS患者。冠脉生理在TAVI前后及随访时（中位5.4个月）进行评估。结果：纳入29例患者，平均年龄81.3岁。中位数（95%置信区间）FFR从tavi前的0.83（0.79-0.84）下降到tavi后的0.81（0.78-0.83）。在充血期间，过境平均时间从0.27（0.19-0.35）秒减少到0.20（0.18-0.27）秒，反映冠状动脉血流增加。基础微血管阻力从24（21-35）增加到32(23-45)，而阻力储备比从1.8（1.5-2.3）增加到2.6 (2.2-3.1)（P=0.002）。因此，冠状动脉血流储备（CFR）明显改善，从1.5（1.2-1.7）到1.9 (1.5-2.4)（P=0.006）。在21例随访患者中，未观察到明显的FFR变化，CFR升高的意义丧失。只有3例患者微血管阻力指数为bbb25，表明充血时微血管受损。结论：在经TAVI治疗严重AS的稳定CAD患者中，瓣膜置换术可立即改善CFR。瓣膜置入术后FFR的下降幅度最小，支持其可重复性，可用于指导此类患者的血运重建。临床试验注册：. nct04663334。

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引用次数: 0

Smoking cessation, weight control and cardiovascular disease: Letter in response to the article entitled “Sex-specific predictive factors of smoking cessation in subjects at high cardiovascular risk” by Allagbé et al. 戒烟、体重控制与心血管疾病：回应 Allagbé 等人题为 "心血管疾病高危人群戒烟的性别特异性预测因素 "一文的信函。

IF 2.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Archives of Cardiovascular Diseases

Pub Date : 2025-04-01 DOI: 10.1016/j.acvd.2024.10.336

Tomoyuki Kawada

引用次数: 0

What's new in the recent updated ESC guidelines on chronic coronary syndrome management?

IF 2.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Archives of Cardiovascular Diseases

Pub Date : 2025-04-01 DOI: 10.1016/j.acvd.2025.01.004

Gilles Lemesle , Hubert Dromas , Nicolas Danchin , Hakim Benamer , Bernard Iung

引用次数: 0

Characterization of left atrial strain in left ventricular hypertrophy: A study of Fabry disease, sarcomeric hypertrophic cardiomyopathy and cardiac amyloidosis

IF 2.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Archives of Cardiovascular Diseases

Pub Date : 2025-04-01 DOI: 10.1016/j.acvd.2024.12.013

Charles Massie , Frédérique Dubé , Soumaya Sridi-Cheniti , Julien Ternacle , Stéphane Lafitte , Patricia Réant

Background

Patients with left ventricular hypertrophy (LVH) often maintain preserved left ventricular ejection fraction in the early stages of the disease. There is a need to identify simple and reliable variables beyond left ventricular ejection fraction to recognize those at risk of developing adverse clinical outcomes.

Aims

To examine left atrial (LA) strain in patients with hypertrophic cardiomyopathy (HCM), cardiac amyloidosis (CA) and Fabry disease (FD), pathologies known to cause LVH, and the relationship between LA strain and adverse clinical outcomes.

Methods

In this retrospective cohort study, LA strain was measured and compared among patients with HCM, CA and FD. Relationships between LA and left ventricular strain, and LA strain and adverse cardiovascular events were evaluated. The primary outcome was first occurrence of cardiovascular mortality, device implantation, heart failure hospitalization, new-onset atrial fibrillation or stroke.

Results

A total of 191 patients were included (24 with FD, 87 with HCM, 80 with CA). LA reservoir strain was highest in patients with HCM (26%, interquartile range [IQR] 20%, 32%), followed by those with FD (20.5%, IQR: 14%, 27.8%) and CA (11%, IQR: 7%, 18.8%) (P < 0.001). LA strain correlated well with left ventricular strain in patients with LVH, with CA showing the best correlation (r = −0.70, 95% confidence interval [95% CI]: −0.80 to −0.56; P < 0.001). Multivariable Cox regression analysis showed that LA reservoir strain was significantly associated with the primary outcome in all patients (hazard ratio: 0.91, 95% CI: 0.84 to 0.99; P = 0.03) and in those with CA (hazard ratio: 0.90, 95% CI: 0.82 to 0.99; P = 0.023).

Conclusions

LA strain was more reduced in CA than in FD and HCM, probably as a result of atrial wall infiltration, and was associated with adverse clinical outcomes in our heterogenous LVH population and patients with CA.

{"title":"Characterization of left atrial strain in left ventricular hypertrophy: A study of Fabry disease, sarcomeric hypertrophic cardiomyopathy and cardiac amyloidosis","authors":"Charles Massie , Frédérique Dubé , Soumaya Sridi-Cheniti , Julien Ternacle , Stéphane Lafitte , Patricia Réant","doi":"10.1016/j.acvd.2024.12.013","DOIUrl":"10.1016/j.acvd.2024.12.013","url":null,"abstract":"<div><h3>Background</h3><div>Patients with left ventricular hypertrophy (LVH) often maintain preserved left ventricular ejection fraction in the early stages of the disease. There is a need to identify simple and reliable variables beyond left ventricular ejection fraction to recognize those at risk of developing adverse clinical outcomes.</div></div><div><h3>Aims</h3><div>To examine left atrial (LA) strain in patients with hypertrophic cardiomyopathy (HCM), cardiac amyloidosis (CA) and Fabry disease (FD), pathologies known to cause LVH, and the relationship between LA strain and adverse clinical outcomes.</div></div><div><h3>Methods</h3><div>In this retrospective cohort study, LA strain was measured and compared among patients with HCM, CA and FD. Relationships between LA and left ventricular strain, and LA strain and adverse cardiovascular events were evaluated. The primary outcome was first occurrence of cardiovascular mortality, device implantation, heart failure hospitalization, new-onset atrial fibrillation or stroke.</div></div><div><h3>Results</h3><div>A total of 191 patients were included (24 with FD, 87 with HCM, 80 with CA). LA reservoir strain was highest in patients with HCM (26%, interquartile range [IQR] 20%, 32%), followed by those with FD (20.5%, IQR: 14%, 27.8%) and CA (11%, IQR: 7%, 18.8%) (<em>P</em>  =−0.70, 95% confidence interval [95% CI]: −0.80 to −0.56; <em>P</em>  =0.03) and in those with CA (hazard ratio: 0.90, 95% CI: 0.82 to 0.99; <em>P</em>  <!-->0.023).</div></div><div><h3>Conclusions</h3><div>LA strain was more reduced in CA than in FD and HCM, probably as a result of atrial wall infiltration, and was associated with adverse clinical outcomes in our heterogenous LVH population and patients with CA.</div></div>","PeriodicalId":55472,"journal":{"name":"Archives of Cardiovascular Diseases","volume":"118 4","pages":"Pages 231-240"},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Koch's triangle and coronary sinus anatomy assessed by three-dimensional electroanatomical mapping in paediatric patients with junctional tachycardia

IF 2.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Archives of Cardiovascular Diseases

Pub Date : 2025-04-01 DOI: 10.1016/j.acvd.2024.11.004

Clément Boiteux , Simon Viscogliosi , Sinan Boissiere , Astrid Monier , Geoffroy Ditac , Roland Henaine , Olivier Metton , Antoine Deliniere , Rémi Thevenard , Nawel Babouri , Kévin Gardey , Francis Bessière

Background

Three-dimensional electroanatomical mapping has become an essential tool in paediatric electrophysiology to precisely identify areas involved in arrhythmias. Anatomical variations in Koch's triangle, especially fluoroscopic enlargement of the coronary sinus ostium, have been found more frequently in patients with atrioventricular nodal reentrant tachycardia (AVNRT) than in those with atrioventricular reentrant tachycardia (AVRT). This finding is consistent with easier coronary sinus cannulation during electrophysiology procedures in patients with AVNRT.

Aim

To explore anatomical differences in the coronary sinus and Koch's triangle between children with AVNRT and AVRT using three-dimensional system acquisitions.

Methods

We conducted a single-centre retrospective study of paediatric patients undergoing a catheter ablation procedure for AVNRT or AVRT. Detailed anatomy of the coronary sinus ostium, global morphology and Koch's triangle properties was assessed via catheter-based intracardiac three-dimensional electroanatomical mapping, and compared.

Results

Forty-four children were enrolled (22 in each group). The median age was 14.6 (interquartile range [IQR] 10.9–16.2) years. The coronary sinus ostium area and diameter were similar in the AVNRT and AVRT groups: area, 1.0 (IQR 0.7–1.2) vs. 1.2 (IQR 0.5–1.6) cm/m², respectively (P = 0.71; 95% confidence interval of median difference –0.3 to 0.3); diameter, 1.0 (IQR 0.8–1.5) vs. 1.1 (IQR 0.9–1.4) cm/m², respectively (P = 0.56; 95% confidence interval of median difference –0.2 to 0.2). Five patients (22.7%) in each group had a coronary sinus with a windsock morphology. There was no difference in the Koch's triangle area between the AVNRT and AVRT groups: 1.4 (IQR 1.1–2.0) vs. 1.6 (IQR 1.3–1.9) cm²/m², respectively (P = 0.37; 95% CI of median difference –0.2 to 0.5).

Conclusions

Our findings suggest no difference in coronary sinus anatomy between these two junctional tachycardias. A potential explanation is the limited ability of three-dimensional mapping technologies to accurately define complex intracardiac structures.

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