首页 > 最新文献

Archives De Pediatrie最新文献

英文 中文
Uncorrected ametropia in children with limited access to ocular health care.
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2025-01-27 DOI: 10.1016/j.arcped.2024.10.008
Omri Clair, Christine Morisset, Rayan Mekoui, Solène De Hedouville, Flavien Lefebvre, Emmanuel Marciano, Emmanuel Bui Quoc

Introduction: The primary objective of this study is to describe the refractive needs of vulnerable children according to their social security status. The secondary objective of this study is to describe the types of ametropia in this population of children with limited access to ocular health care.

Methods: Children with limited access to ocular health care were recruited. Their social security status was assessed as well as their need for optical correction. Children received an orthoptic and ophthalmological examination. The ametropia thresholds requiring optical correction were defined as follows: hyperopia if spherical equivalent (SE) ≥ 3D before 6 years, ≥ 2.25 D between 6 and 12 years, ≥ 1.5 D from 12 years onwards; myopia if SE ≤ 0.5 D; astigmatism if cylinder C ≥ 1D; anisometropia if sphere difference between both eyes ≥ 1D.

Results: Out of 83 planned patients, 60 children turned up. 51 files for children aged 1 to 14 years old were analysed. 63.2 % of children without social security required an optical correction, compared with 65.6 % of children receiving State Medical Aid (SMA) and 66.7 % of children receiving Universal Health Protection (UHP). Out of 102 eyes, SE was hypermetropic in 56.9 % of cases, myopic in 21.6 % of cases; astigmatism was present in 60.8 % of cases. Anisometropia was assessed in 27.5 % of cases. 33 children out of 51 (64.7 %) required correction with glasses.

Discussion and conclusion: Children benefiting from SMA or UHP have similar refractive needs than children without social security, and probably greater than those of the general population. In our population there is two-thirds of patients with ametropia requiring optical correction; most of these children did not initially wear glasses, which suggests that access to ophthalmic and optical care is more difficult for vulnerable children.

{"title":"Uncorrected ametropia in children with limited access to ocular health care.","authors":"Omri Clair, Christine Morisset, Rayan Mekoui, Solène De Hedouville, Flavien Lefebvre, Emmanuel Marciano, Emmanuel Bui Quoc","doi":"10.1016/j.arcped.2024.10.008","DOIUrl":"https://doi.org/10.1016/j.arcped.2024.10.008","url":null,"abstract":"<p><strong>Introduction: </strong>The primary objective of this study is to describe the refractive needs of vulnerable children according to their social security status. The secondary objective of this study is to describe the types of ametropia in this population of children with limited access to ocular health care.</p><p><strong>Methods: </strong>Children with limited access to ocular health care were recruited. Their social security status was assessed as well as their need for optical correction. Children received an orthoptic and ophthalmological examination. The ametropia thresholds requiring optical correction were defined as follows: hyperopia if spherical equivalent (SE) ≥ 3D before 6 years, ≥ 2.25 D between 6 and 12 years, ≥ 1.5 D from 12 years onwards; myopia if SE ≤ 0.5 D; astigmatism if cylinder C ≥ 1D; anisometropia if sphere difference between both eyes ≥ 1D.</p><p><strong>Results: </strong>Out of 83 planned patients, 60 children turned up. 51 files for children aged 1 to 14 years old were analysed. 63.2 % of children without social security required an optical correction, compared with 65.6 % of children receiving State Medical Aid (SMA) and 66.7 % of children receiving Universal Health Protection (UHP). Out of 102 eyes, SE was hypermetropic in 56.9 % of cases, myopic in 21.6 % of cases; astigmatism was present in 60.8 % of cases. Anisometropia was assessed in 27.5 % of cases. 33 children out of 51 (64.7 %) required correction with glasses.</p><p><strong>Discussion and conclusion: </strong>Children benefiting from SMA or UHP have similar refractive needs than children without social security, and probably greater than those of the general population. In our population there is two-thirds of patients with ametropia requiring optical correction; most of these children did not initially wear glasses, which suggests that access to ophthalmic and optical care is more difficult for vulnerable children.</p>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study of physical activity in obese adolescents in Algeria. 阿尔及利亚肥胖青少年的体育活动研究。
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2025-01-10 DOI: 10.1016/j.arcped.2024.09.009
Fouzia Yous, Salim Zaabar, Omar Aoun, Nawel Adjeroud-Abdellatif, Radia Arab, Khodir Madani

Objective: Adolescents are meant to spend a large part of their time practicing a hobby or sport, but currently there is a decline in their level of physical activity and sport both inside and outside schools, which can lead to a risk of obesity. The objective of the present study was to examine physical activity in obese adolescents within the school establishments of the province of Bejaia (northeastern Algeria).

Method: To determine the physical activity level (PAL) in the school population, a sample of 3,038 students with obesity comprising 1,635 girls and 1,403 boys was selected. The study focused on (a) the comparison of the intensity of physical activities practiced by girls and boys, (ii) the determination of the duration, intensity, and level of physical activity.

Results: The results show that obese girls are less active than obese boys at all ages (from 11 to 23 years) and in all locations; PALs was steady with increasing age for girls, while PALs increase with age in boys from 17 to 21. We found that some factors are associated with a decrease in PAL, such as the time spent watching television. Doing only 30 min of physical activity once a week is associated with an increase in sedentary behavior. The mean PALs of middle school (1.54) and high school (1.50) girls were lower than those observed for middle school (1.75) and high school (1.65) boys.

Conclusions: Our results show that obese girls are less active than obese boys and spend time watching television and practicing sports only at school.

目的:青少年应该把大部分时间花在一项爱好或运动上,但目前他们在学校内外的体育活动和运动水平都在下降,这可能导致肥胖的风险。本研究的目的是调查贝加亚省(阿尔及利亚东北部)学校机构内肥胖青少年的体育活动情况。方法:选取3038名肥胖学生(其中女生1635名,男生1403名)进行体质活动水平(physical activity level, PAL)测定。该研究侧重于(a)女孩和男孩进行体育活动强度的比较,(ii)确定体育活动的持续时间、强度和水平。结果:结果显示,在所有年龄段(11 ~ 23岁)和所有地区,肥胖女孩的活动量均低于肥胖男孩;女孩的pal随年龄增长而稳定,而男孩的pal随年龄增长而增加,从17岁到21岁。我们发现一些因素与PAL下降有关,比如看电视的时间。每周只进行一次30分钟的体育活动与久坐行为的增加有关。初中女生(1.54)和高中女生(1.50)的平均pal低于初中男生(1.75)和高中男生(1.65)。结论:我们的研究结果表明,肥胖女孩比肥胖男孩更不活跃,只在学校花时间看电视和进行体育锻炼。
{"title":"Study of physical activity in obese adolescents in Algeria.","authors":"Fouzia Yous, Salim Zaabar, Omar Aoun, Nawel Adjeroud-Abdellatif, Radia Arab, Khodir Madani","doi":"10.1016/j.arcped.2024.09.009","DOIUrl":"https://doi.org/10.1016/j.arcped.2024.09.009","url":null,"abstract":"<p><strong>Objective: </strong>Adolescents are meant to spend a large part of their time practicing a hobby or sport, but currently there is a decline in their level of physical activity and sport both inside and outside schools, which can lead to a risk of obesity. The objective of the present study was to examine physical activity in obese adolescents within the school establishments of the province of Bejaia (northeastern Algeria).</p><p><strong>Method: </strong>To determine the physical activity level (PAL) in the school population, a sample of 3,038 students with obesity comprising 1,635 girls and 1,403 boys was selected. The study focused on (a) the comparison of the intensity of physical activities practiced by girls and boys, (ii) the determination of the duration, intensity, and level of physical activity.</p><p><strong>Results: </strong>The results show that obese girls are less active than obese boys at all ages (from 11 to 23 years) and in all locations; PALs was steady with increasing age for girls, while PALs increase with age in boys from 17 to 21. We found that some factors are associated with a decrease in PAL, such as the time spent watching television. Doing only 30 min of physical activity once a week is associated with an increase in sedentary behavior. The mean PALs of middle school (1.54) and high school (1.50) girls were lower than those observed for middle school (1.75) and high school (1.65) boys.</p><p><strong>Conclusions: </strong>Our results show that obese girls are less active than obese boys and spend time watching television and practicing sports only at school.</p>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thigh and paraspinal muscles change after fusionless bipolar fixation for early onset scoliosis in type 2 spinal muscular atrophy 无融合双极固定术治疗2型脊髓性肌萎缩症早发性脊柱侧弯后大腿和脊柱旁肌肉的变化:SMA2和早发性脊柱侧弯患者脊柱和大腿肌肉的变化。
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2025-01-01 DOI: 10.1016/j.arcped.2024.08.005
Mathilde Gaume , Claudio Vergari , Maud Creze , Aurore Bonnet-Lebrun , Christophe Muth-Seng , Susana Quijano-Roy , Lotfi Miladi , Wafa Skalli , Robert-Yves Carlier

Background

Spinal muscular atrophy is a severe, progressive autosomal recessive neuromuscular disorder associated with neuromuscular scoliosis. When bracing is not sufficient to control the deformity, early spinal surgery is required. To the best of our knowledge, no work in the literature have assessed modifications in spinal and thigh muscles of subjects with type 2 spinal muscular atrophy (SMA2) following spinal surgery.

Objective

This study aimed to better understand modifications in the spinal and thigh muscles of subjects with SMA2 and early onset scoliosis, before and after minimally invasive fusionless surgery.

Methods and settings

20 SMA2 patients with confirmed scoliosis on bi-planar low-dose X-ray were included: 10 preoperative and 10 postoperative patients with a minimal follow-up of 5 years after surgery. The surgery consisted of a bilateral sliding rod construct extended from T1 to the sacrum, through a minimally invasive approach. All subjects had fat/water separation muscle magnetic resonance imaging from the spine to the thigh. The percentage of fat degeneration was compared before and after surgery. A quality-of-life survey was performed.

Results

Fat infiltration was diffuse and symmetric in both groups of patients, and on average six times more compared to control subjects previously published at thigh level. Adductors, sartorius, and gracilis were less affected with respectively, 51%, 56%, and 57% of fat fraction before surgery. Comparing the preoperative and postoperative groups, fat infiltration was higher in sartorius and multifidus after surgery (p < 0.05). No significant difference was found for the other muscles studied. These results did not affect quality of life.

Conclusion

This is the first study to compare fat infiltration of spinal and thigh muscles of SMA2 patients before and after minimally invasive surgery. Our results demonstrate that muscles were globally preserved apart from multifidus and sartorius which were more affected.
背景:脊髓性肌萎缩症是一种严重的进行性常染色体隐性神经肌肉疾病,伴有神经肌肉性脊柱侧弯。当支撑物不足以控制畸形时,就需要尽早进行脊柱手术。据我们所知,目前还没有文献对脊柱手术后 2 型脊髓性肌萎缩症(SMA2)患者脊柱和大腿肌肉的变化进行评估:本研究旨在更好地了解微创无融合手术前后 SMA2 患者脊柱和大腿肌肉的变化情况:方法:20 名经双平面低剂量 X 光检查确诊为脊柱侧弯的 SMA2 患者:10 名术前患者和 10 名术后患者,术后随访最短 5 年。手术包括通过微创方法将双侧滑动杆结构从 T1 扩展到骶骨。所有受试者都进行了从脊柱到大腿的脂肪/水分离肌肉磁共振成像检查。手术前后的脂肪退化百分比进行了比较。还进行了生活质量调查:两组患者的脂肪浸润均呈弥漫性和对称性,与之前发表的大腿水平对照组相比,平均多出六倍。内收肌、腓肠肌和腓肠肌受影响较小,术前脂肪比例分别为51%、56%和57%。对比术前和术后两组,术后腓肠肌和多裂肌的脂肪浸润率更高(P < 0.05)。所研究的其他肌肉没有发现明显差异。这些结果不会影响生活质量:这是第一项比较微创手术前后 SMA2 患者脊柱和大腿肌肉脂肪浸润情况的研究。我们的研究结果表明,除了多裂肌和腓肠肌受影响较大外,其他肌肉在整体上都得到了保留。
{"title":"Thigh and paraspinal muscles change after fusionless bipolar fixation for early onset scoliosis in type 2 spinal muscular atrophy","authors":"Mathilde Gaume ,&nbsp;Claudio Vergari ,&nbsp;Maud Creze ,&nbsp;Aurore Bonnet-Lebrun ,&nbsp;Christophe Muth-Seng ,&nbsp;Susana Quijano-Roy ,&nbsp;Lotfi Miladi ,&nbsp;Wafa Skalli ,&nbsp;Robert-Yves Carlier","doi":"10.1016/j.arcped.2024.08.005","DOIUrl":"10.1016/j.arcped.2024.08.005","url":null,"abstract":"<div><h3>Background</h3><div>Spinal muscular atrophy is a severe, progressive autosomal recessive neuromuscular disorder associated with neuromuscular scoliosis. When bracing is not sufficient to control the deformity, early spinal surgery is required. To the best of our knowledge, no work in the literature have assessed modifications in spinal and thigh muscles of subjects with type 2 spinal muscular atrophy (SMA2) following spinal surgery.</div></div><div><h3>Objective</h3><div>This study aimed to better understand modifications in the spinal and thigh muscles of subjects with SMA2 and early onset scoliosis, before and after minimally invasive fusionless surgery.</div></div><div><h3>Methods and settings</h3><div>20 SMA2 patients with confirmed scoliosis on bi-planar low-dose X-ray were included: 10 preoperative and 10 postoperative patients with a minimal follow-up of 5 years after surgery. The surgery consisted of a bilateral sliding rod construct extended from T1 to the sacrum, through a minimally invasive approach. All subjects had fat/water separation muscle magnetic resonance imaging from the spine to the thigh. The percentage of fat degeneration was compared before and after surgery. A quality-of-life survey was performed.</div></div><div><h3>Results</h3><div>Fat infiltration was diffuse and symmetric in both groups of patients, and on average six times more compared to control subjects previously published at thigh level. Adductors, sartorius, and gracilis were less affected with respectively, 51%, 56%, and 57% of fat fraction before surgery. Comparing the preoperative and postoperative groups, fat infiltration was higher in sartorius and multifidus after surgery (<em>p</em> &lt; 0.05). No significant difference was found for the other muscles studied. These results did not affect quality of life.</div></div><div><h3>Conclusion</h3><div>This is the first study to compare fat infiltration of spinal and thigh muscles of SMA2 patients before and after minimally invasive surgery. Our results demonstrate that muscles were globally preserved apart from multifidus and sartorius which were more affected.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 1","pages":"Pages 12-17"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of early discharge from the maternity ward on the risk of neonatal rehospitalization: A case-control study 产房提前出院对新生儿再次住院风险的影响:病例对照研究。
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2025-01-01 DOI: 10.1016/j.arcped.2024.09.003
Cassandra VAROQUI , Abdou Yacoubou OMOROU , Laurélia JOURDAN , Jean-Michel HASCOET

Background

The time for newborn discharge from the maternity ward has been shortened in recent decades with consequences that are still debated.

Objectives

The primary objective of this study was to establish whether early discharge could be a risk factor for rehospitalization in the neonatal period. Second, we aimed to study the incidence of neonatal hospitalizations and their causes. Next, we tried to determine other possible risk factors for rehospitalization after discharge.

Methods and Setting

This is a retrospective, single-center, case-control study collecting data on newborns rehospitalized in the first 28 days of life at Nancy University Hospital, after their discharge from the maternity ward. These newborns were born between 01/06/2021 and 31/05/2022 and were matched with two healthy infants who did not require rehospitalization according to term and month of birth. A logistic regression model was used to evaluate the association between early discharge and risk of hospitalization.

Results

2,054 healthy full-term babies were born during the study period; 108 (5%) were rehospitalized and compared to 219 randomly selected newborns who did not required hospitalization. Among the 108 cases included, 42 (38.9%) obtained early discharge versus 91 out of 219 (41.6%) controls. Multivariate logistic regression showed no significant association between early discharge and risk of hospitalization (ORa=1.1 [95%CI: 0.7 to 1.8], p = 0.69). However, phototherapy treatment during the maternity ward stay was a significant risk factor for rehospitalization (ORa=5.O [2.5 to 9.9], p < 0.0001). The main causes of hospitalization were jaundice and respiratory infections.

Conclusion

Early discharge from the maternity ward does not constitute a risk factor for readmission in the neonatal period in this study. Changes in perinatal practices, such as ambulatory delivery and very early discharge, should be included in revised recommendations.
背景:近几十年来,新生儿离开产科病房的时间不断缩短,但其后果仍存在争议:本研究的主要目的是确定提前出院是否会成为新生儿期再次住院的风险因素。其次,我们旨在研究新生儿住院的发生率及其原因。其次,我们试图确定出院后再次住院的其他可能风险因素:这是一项回顾性、单中心、病例对照研究,收集了南锡大学医院新生儿出院后 28 天内再次住院的数据。这些新生儿出生日期在 2021 年 6 月 1 日至 2022 年 5 月 31 日之间,并与两名无需再次住院的健康婴儿按出生月份和足月进行了配对。结果:研究期间共出生了 2,054 名健康足月婴儿,其中 108 名(5%)再次住院,并与随机抽取的 219 名无需住院的新生儿进行了比较。在 108 例病例中,有 42 例(38.9%)提前出院,而在 219 例对照中,有 91 例(41.6%)提前出院。多变量逻辑回归显示,提前出院与住院风险之间无明显关联(ORa=1.1 [95%CI: 0.7 to 1.8],p = 0.69)。然而,产科病房住院期间的光疗是再次住院的一个重要风险因素(ORa=5.O [2.5 至 9.9],P < 0.0001)。住院的主要原因是黄疸和呼吸道感染:结论:在本研究中,产科病房提前出院并不构成新生儿期再次入院的风险因素。围产期做法的改变,如非卧床分娩和过早出院,应纳入修订后的建议中。
{"title":"Impact of early discharge from the maternity ward on the risk of neonatal rehospitalization: A case-control study","authors":"Cassandra VAROQUI ,&nbsp;Abdou Yacoubou OMOROU ,&nbsp;Laurélia JOURDAN ,&nbsp;Jean-Michel HASCOET","doi":"10.1016/j.arcped.2024.09.003","DOIUrl":"10.1016/j.arcped.2024.09.003","url":null,"abstract":"<div><h3>Background</h3><div>The time for newborn discharge from the maternity ward has been shortened in recent decades with consequences that are still debated.</div></div><div><h3>Objectives</h3><div>The primary objective of this study was to establish whether early discharge could be a risk factor for rehospitalization in the neonatal period. Second, we aimed to study the incidence of neonatal hospitalizations and their causes. Next, we tried to determine other possible risk factors for rehospitalization after discharge.</div></div><div><h3>Methods and Setting</h3><div>This is a retrospective, single-center, case-control study collecting data on newborns rehospitalized in the first 28 days of life at Nancy University Hospital, after their discharge from the maternity ward. These newborns were born between 01/06/2021 and 31/05/2022 and were matched with two healthy infants who did not require rehospitalization according to term and month of birth. A logistic regression model was used to evaluate the association between early discharge and risk of hospitalization.</div></div><div><h3>Results</h3><div>2,054 healthy full-term babies were born during the study period; 108 (5%) were rehospitalized and compared to 219 randomly selected newborns who did not required hospitalization. Among the 108 cases included, 42 (38.9%) obtained early discharge versus 91 out of 219 (41.6%) controls. Multivariate logistic regression showed no significant association between early discharge and risk of hospitalization (ORa=1.1 [95%CI: 0.7 to 1.8], <em>p</em> = 0.69). However, phototherapy treatment during the maternity ward stay was a significant risk factor for rehospitalization (ORa=5.O [2.5 to 9.9], <em>p</em> &lt; 0.0001). The main causes of hospitalization were jaundice and respiratory infections.</div></div><div><h3>Conclusion</h3><div>Early discharge from the maternity ward does not constitute a risk factor for readmission in the neonatal period in this study. Changes in perinatal practices, such as ambulatory delivery and very early discharge, should be included in revised recommendations.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 1","pages":"Pages 58-65"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Re: Cow's milk-based infant formula supplements in breastfed infants and primary prevention of cow's milk allergy: A commentary of the Committee on Nutrition of the French Society of Pediatrics 关于母乳喂养婴儿的牛奶基婴儿配方辅食和牛奶过敏的一级预防:法国儿科学会营养委员会的评论。
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2025-01-01 DOI: 10.1016/j.arcped.2024.10.004
Dominique Sabouraud-Leclerc , Elena Bradatan , Tomas Moraly , François Payot , Anne Broué-Chabbert , Rachel Pontcharraud , Carine Larue , Ariane Nemni , Agnès Juchet , Patrick Tounian
{"title":"Re: Cow's milk-based infant formula supplements in breastfed infants and primary prevention of cow's milk allergy: A commentary of the Committee on Nutrition of the French Society of Pediatrics","authors":"Dominique Sabouraud-Leclerc ,&nbsp;Elena Bradatan ,&nbsp;Tomas Moraly ,&nbsp;François Payot ,&nbsp;Anne Broué-Chabbert ,&nbsp;Rachel Pontcharraud ,&nbsp;Carine Larue ,&nbsp;Ariane Nemni ,&nbsp;Agnès Juchet ,&nbsp;Patrick Tounian","doi":"10.1016/j.arcped.2024.10.004","DOIUrl":"10.1016/j.arcped.2024.10.004","url":null,"abstract":"","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 1","pages":"Pages 77-78"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Caregiver satisfaction with the use of continuous glucose monitoring and flash glucose monitoring in very young children with type 1 diabetes 照顾者对非常年幼的1型糖尿病儿童使用连续血糖监测和瞬时血糖监测的满意度
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2025-01-01 DOI: 10.1016/j.arcped.2024.09.005
Karine Aouchiche , Delphine Bernoux , Elisabeth Baechler Sadoul , Elsa Haine , Florence Joubert , Sophie Epstein , Noémie Faure Galon , Fabienne Dalla-Vale , Jean․-Charles Combe , Martine Samper , Gilbert Simonin , Sarah Castets , Emeline Marquant , Julia Vergier , Rachel Reynaud

Background

New technologies for the management of children with type 1 diabete (T1D) are constantly and rapidly evolving. However, few real-life studies have been conducted, and rarely in the youngest patients (<6 years).

Aim

To study parental satisfaction with continuous and flash glucose monitoring devices in young children with T1D.

Methods

A questionnaire was completed by the parents of 114 children under the age of 6 years with T1D treated with an insulin pump followed-up in one of the hospitals of the French ADIM network between January and July 2020.

Results

One hundred and nine patients (96 %) were equipped with a glucose monitor and 95 % (104/109) of parents stated that they were satisfied or very satisfied with their child's monitoring device, with no significant difference in satisfaction rates between flash and continuous glucose monitoring. The parameter most strongly associated with satisfaction was confidence in the reliability of the device (p = 0.008). Parents who struggled to apply the device were significantly less satisfied (p = 0.024). In real-life use, 83 % of parents (90/109) used additional adhesives, 28 % reported mild skin reactions (30/108) and 39 % severe skin reactions (42/108), 50 % stated that applying the device was not painful, and 95 % found the device easy to apply. The most commonly reported unexpected difficulties were device malfunction (by 16 respondents), the device being too large and causing scarring (6 respondents), and lengthy calibration (6 respondents).

Conclusion

The vast majority of parents in this group of young children with T1D were satisfied with continuous or flash glucose monitoring. Satisfaction was strongly associated with confidence in the reliability of the device. Reported adverse effects such as skin reaction and difficulties attaching the device highlight the importance of data on real-life use.
背景:儿童1型糖尿病(T1D)治疗的新技术不断快速发展。然而,很少有现实生活中的研究进行,而且很少在最年轻的患者中进行(目的:研究父母对T1D儿童连续和闪变血糖监测装置的满意度。方法:对2020年1月至7月在法国ADIM网络的一家医院接受胰岛素泵治疗的114名6岁以下T1D儿童的父母进行问卷调查。结果:109例患者(96%)配备了血糖监护仪,95%(104/109)的家长对孩子的血糖监护仪表示满意或非常满意,瞬时血糖监护与连续血糖监护满意率无显著差异。与满意度最密切相关的参数是对设备可靠性的信心(p = 0.008)。难以使用该设备的家长满意度明显较低(p = 0.024)。在实际使用中,83%的家长(90/109)使用了额外的粘合剂,28%报告轻微的皮肤反应(30/108),39%报告严重的皮肤反应(42/108),50%的人表示使用该设备并不痛苦,95%的人发现该设备易于使用。最常见的意外困难是设备故障(16名受访者),设备太大并造成疤痕(6名受访者),以及校准时间长(6名受访者)。结论:本组年幼T1D患儿绝大多数家长对连续或瞬时血糖监测满意。满意度与对设备可靠性的信心密切相关。报告的不良反应,如皮肤反应和连接设备的困难,突出了实际使用数据的重要性。
{"title":"Caregiver satisfaction with the use of continuous glucose monitoring and flash glucose monitoring in very young children with type 1 diabetes","authors":"Karine Aouchiche ,&nbsp;Delphine Bernoux ,&nbsp;Elisabeth Baechler Sadoul ,&nbsp;Elsa Haine ,&nbsp;Florence Joubert ,&nbsp;Sophie Epstein ,&nbsp;Noémie Faure Galon ,&nbsp;Fabienne Dalla-Vale ,&nbsp;Jean․-Charles Combe ,&nbsp;Martine Samper ,&nbsp;Gilbert Simonin ,&nbsp;Sarah Castets ,&nbsp;Emeline Marquant ,&nbsp;Julia Vergier ,&nbsp;Rachel Reynaud","doi":"10.1016/j.arcped.2024.09.005","DOIUrl":"10.1016/j.arcped.2024.09.005","url":null,"abstract":"<div><h3>Background</h3><div>New technologies for the management of children with type 1 diabete (T1D) are constantly and rapidly evolving. However, few real-life studies have been conducted, and rarely in the youngest patients (&lt;6 years).</div></div><div><h3>Aim</h3><div>To study parental satisfaction with continuous and flash glucose monitoring devices in young children with T1D.</div></div><div><h3>Methods</h3><div>A questionnaire was completed by the parents of 114 children under the age of 6 years with T1D treated with an insulin pump followed-up in one of the hospitals of the French ADIM network between January and July 2020.</div></div><div><h3>Results</h3><div>One hundred and nine patients (96 %) were equipped with a glucose monitor and 95 % (104/109) of parents stated that they were satisfied or very satisfied with their child's monitoring device, with no significant difference in satisfaction rates between flash and continuous glucose monitoring. The parameter most strongly associated with satisfaction was confidence in the reliability of the device (<em>p</em> = 0.008). Parents who struggled to apply the device were significantly less satisfied (<em>p</em> = 0.024). In real-life use, 83 % of parents (90/109) used additional adhesives, 28 % reported mild skin reactions (30/108) and 39 % severe skin reactions (42/108), 50 % stated that applying the device was not painful, and 95 % found the device easy to apply. The most commonly reported unexpected difficulties were device malfunction (by 16 respondents), the device being too large and causing scarring (6 respondents), and lengthy calibration (6 respondents).</div></div><div><h3>Conclusion</h3><div>The vast majority of parents in this group of young children with T1D were satisfied with continuous or flash glucose monitoring. Satisfaction was strongly associated with confidence in the reliability of the device. Reported adverse effects such as skin reaction and difficulties attaching the device highlight the importance of data on real-life use.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 1","pages":"Pages 36-40"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Re: Medical management of vegetarian and vegan children in France: Medical practices and parents’ perceptions 关于法国素食和纯素儿童的医疗管理:医疗实践和家长的看法。
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2025-01-01 DOI: 10.1016/j.arcped.2024.10.005
Damien Denimal
{"title":"Re: Medical management of vegetarian and vegan children in France: Medical practices and parents’ perceptions","authors":"Damien Denimal","doi":"10.1016/j.arcped.2024.10.005","DOIUrl":"10.1016/j.arcped.2024.10.005","url":null,"abstract":"","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 1","pages":"Pages 79-80"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Actual food consumption after a negative oral food challenge in children: A challenge after the challenge? 儿童口腔食物负挑战后的实际食物消耗量:挑战之后的挑战?
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2025-01-01 DOI: 10.1016/j.arcped.2024.09.004
Inès Himeur , Delphine Pouradier , Hélène Lengliné , Flore Amat

Background

Unnecessary dietary eliminations may impair quality of life, affect children's growth, and negatively impact healthcare costs. Previous studies reported that around 11 % to 28 % of children continue a food-avoidance diet despite a negative oral food challenge (OFC).

Objectives

This study aimed to evaluate the actual consumption at home of the tested food after a negative OFC and the reasons reported by families in the case of persistent avoidance.

Methods and settings

A retrospective study was conducted in the Pediatric Gastro-Enterology and Pneumo-Allergology Departments of Robert Debré Hospital (Paris), involving patients who had a negative OFC. Data were collected from the patients’ medical files and supplemented by a telephone survey.

Results

101 families completed the telephone survey, corresponding to 129 OFCs with full data available. The tested foods were tree nuts for 29.5 % (38/129), milk for 28.7 % (37/129), and egg for 21 % (27/129). Persistent avoidance represented 17.1 % of the OFCs (22/129), and partial consumption 4.6 % (6/129). Consumption of the tested food was inversely correlated with child's age and length of avoidance period. Consumption was more frequent in the case of ubiquitous allergens (milk, egg). The main causes mentioned for non-consumption were family habits (72.7 %, 16/22) or the child's disgust for the tested food (54.5 %, 12/22).

Conclusion

A negative OFC does not always result in actual consumption of the tested food at home. These results underline the importance of performing an OFC as early as possible in the patient's life. Monitoring and supporting patients who have a negative OFC is key for successful consumption at home.
背景:不必要的饮食禁忌可能会损害生活质量、影响儿童生长并对医疗成本产生负面影响。以往的研究报告显示,约有 11% 至 28% 的儿童在口服食物挑战(OFC)呈阴性反应后仍继续避免进食:本研究旨在评估儿童在口服食物试验(OFC)阴性后在家实际食用试验食物的情况,以及在持续回避的情况下家庭报告的原因:巴黎罗伯特-德布雷医院(Robert Debré)小儿胃肠病科和肺炎过敏科开展了一项回顾性研究,研究对象为OFC阴性的患者。数据来自患者的医疗档案,并通过电话调查进行补充:101个家庭完成了电话调查,对应129名有完整数据的OFC患者。接受检测的食物中,29.5%(38/129)为树坚果,28.7%(37/129)为牛奶,21%(27/129)为鸡蛋。持续回避占 OFCs 的 17.1%(22/129),部分食用占 4.6%(6/129)。食用测试食物与儿童的年龄和回避期的长短成反比。食用无处不在的过敏原(牛奶、鸡蛋)的频率更高。不食用的主要原因是家庭习惯(72.7%,16/22)或儿童对测试食物的厌恶(54.5%,12/22):结论:OFC 阴性并不总是导致儿童在家中实际食用被测食物。这些结果强调了在患者生活中尽早进行 OFC 的重要性。监测和支持 OFC 阴性的患者是成功在家进食的关键。
{"title":"Actual food consumption after a negative oral food challenge in children: A challenge after the challenge?","authors":"Inès Himeur ,&nbsp;Delphine Pouradier ,&nbsp;Hélène Lengliné ,&nbsp;Flore Amat","doi":"10.1016/j.arcped.2024.09.004","DOIUrl":"10.1016/j.arcped.2024.09.004","url":null,"abstract":"<div><h3>Background</h3><div>Unnecessary dietary eliminations may impair quality of life, affect children's growth, and negatively impact healthcare costs. Previous studies reported that around 11 % to 28 % of children continue a food-avoidance diet despite a negative oral food challenge (OFC).</div></div><div><h3>Objectives</h3><div>This study aimed to evaluate the actual consumption at home of the tested food after a negative OFC and the reasons reported by families in the case of persistent avoidance.</div></div><div><h3>Methods and settings</h3><div>A retrospective study was conducted in the Pediatric Gastro-Enterology and Pneumo-Allergology Departments of Robert Debré Hospital (Paris), involving patients who had a negative OFC. Data were collected from the patients’ medical files and supplemented by a telephone survey.</div></div><div><h3>Results</h3><div>101 families completed the telephone survey, corresponding to 129 OFCs with full data available. The tested foods were tree nuts for 29.5 % (38/129), milk for 28.7 % (37/129), and egg for 21 % (27/129). Persistent avoidance represented 17.1 % of the OFCs (22/129), and partial consumption 4.6 % (6/129). Consumption of the tested food was inversely correlated with child's age and length of avoidance period. Consumption was more frequent in the case of ubiquitous allergens (milk, egg). The main causes mentioned for non-consumption were family habits (72.7 %, 16/22) or the child's disgust for the tested food (54.5 %, 12/22).</div></div><div><h3>Conclusion</h3><div>A negative OFC does not always result in actual consumption of the tested food at home. These results underline the importance of performing an OFC as early as possible in the patient's life. Monitoring and supporting patients who have a negative OFC is key for successful consumption at home.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 1","pages":"Pages 48-51"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between visceral adipose tissue and glomerular hyperfiltration in adolescents: A cross-sectional study 青少年内脏脂肪组织与肾小球高滤过率之间的关系:横断面研究
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2025-01-01 DOI: 10.1016/j.arcped.2024.08.007
Yong-Chang Yang, Jing-Ying Zhao, Cheng-Guang Zhao

Objective

Glomerular hyperfiltration is an early indicator of obesity-related glomerular disease. However, in adolescents, there are no quantifiable indicators of obesity and glomerular hyperfiltration. This study investigates the association between visceral adipose tissue and glomerular hyperfiltration in adolescents.

Methods

This cross-sectional study used data from the National Health and Nutrition Examination Survey (NHANES; 2011–2018), and adolescents aged 12–17 years were included. Visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) formed the independent variables while estimated glomerular filtration rate (eGFR) acted as the dependent variable. Their association was assessed using unadjusted and multivariate regression analyses, as well as subgroup and interaction analyses.

Results

Multivariate regression analysis revealed that VAT was positively associated with eGFR and glomerular hyperfiltration among adolescents. The incidence of glomerular hyperfiltration increased by 99 % in boys and 56 % in girls per 100 g of VAT increase. Additionally, VAT and eGFR exhibited a linear relationship in both boys (β = 5.63, p < 0.001) and girls (β = 2.72, p < 0.001).

Conclusions

In US adolescents aged 12–17 years, VAT was positively correlated with eGFR and glomerular hyperfiltration.
目的:肾小球高滤过是肥胖相关肾小球疾病的早期指标。然而,在青少年中,还没有肥胖和肾小球高滤过率的量化指标。本研究调查了青少年内脏脂肪组织与肾小球高滤过率之间的关系:这项横断面研究使用了美国国家健康与营养调查(NHANES;2011-2018 年)的数据,纳入了 12-17 岁的青少年。内脏脂肪组织(VAT)和皮下脂肪组织(SAT)为自变量,估计肾小球滤过率(eGFR)为因变量。使用未调整和多变量回归分析以及亚组和交互分析评估了它们之间的关联:结果:多变量回归分析表明,增值税与青少年的 eGFR 和肾小球高滤过率呈正相关。VAT 每增加 100 克,男孩肾小球高滤过率增加 99%,女孩增加 56%。此外,男孩(β = 5.63,p < 0.001)和女孩(β = 2.72,p < 0.001)的脂肪体积与肾小球滤过率呈线性关系:结论:在 12-17 岁的美国青少年中,VAT 与 eGFR 和肾小球高滤过率呈正相关。
{"title":"Association between visceral adipose tissue and glomerular hyperfiltration in adolescents: A cross-sectional study","authors":"Yong-Chang Yang,&nbsp;Jing-Ying Zhao,&nbsp;Cheng-Guang Zhao","doi":"10.1016/j.arcped.2024.08.007","DOIUrl":"10.1016/j.arcped.2024.08.007","url":null,"abstract":"<div><h3>Objective</h3><div>Glomerular hyperfiltration is an early indicator of obesity-related glomerular disease. However, in adolescents, there are no quantifiable indicators of obesity and glomerular hyperfiltration. This study investigates the association between visceral adipose tissue and glomerular hyperfiltration in adolescents.</div></div><div><h3>Methods</h3><div>This cross-sectional study used data from the National Health and Nutrition Examination Survey (NHANES; 2011–2018), and adolescents aged 12–17 years were included. Visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) formed the independent variables while estimated glomerular filtration rate (eGFR) acted as the dependent variable. Their association was assessed using unadjusted and multivariate regression analyses, as well as subgroup and interaction analyses.</div></div><div><h3>Results</h3><div>Multivariate regression analysis revealed that VAT was positively associated with eGFR and glomerular hyperfiltration among adolescents. The incidence of glomerular hyperfiltration increased by 99 % in boys and 56 % in girls per 100 g of VAT increase. Additionally, VAT and eGFR exhibited a linear relationship in both boys (<em>β</em> = 5.63, <em>p</em> &lt; 0.001) and girls (<em>β</em> = 2.72, <em>p</em> &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>In US adolescents aged 12–17 years, VAT was positively correlated with eGFR and glomerular hyperfiltration.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 1","pages":"Pages 24-29"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of a nurse-driven noninvasive respiratory support discontinuation protocol in infants with severe bronchiolitis 护士主导的无创呼吸支持停用方案对重症支气管炎婴儿的影响。
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2025-01-01 DOI: 10.1016/j.arcped.2024.08.006
Julie Cassibba , Marie Chevallier , Aurélie Alexandre , Alice Fumagalli , Brigitte Fauroux , Guillaume Mortamet

Background

To evaluate a nurse-driven respiratory support discontinuation protocol in infants with bronchiolitis admitted in paediatric intensive care units.

Methods

A retrospective single-center study with pre-versus-post comparative design in a tertiary center.

Results

In total, 187 infants (95 with standard and 92 with nurse-driven protocols) were included. There was no difference in terms of weaning failure between the two periods (11 (12 %) versus 14 (15 %), p = 0.46). During the nurse-driven protocol period, discontinuation of the ventilatory support was performed later (at 44 hrs (IQR 29–67) versus 33 hrs (IQR 19–46), p = 0.001), but the weaning process duration was shorter than before protocol implementation (24 h (IQR 0–60) versus 39 (IQR 18–64), p = 0.01). The total duration of ventilation (excluding time on BiPAP) was similar before and after protocol (53 (IQR 37–81) versus 55 h (IQR 28–81), p = 0.46). The PICU and hospital lengths of stay did not differ between the two periods.

Conclusions

In patients with bronchiolitis supported by noninvasive respiratory support, the nurse-driven discontinuation management - as opposed to physician-driven – was associated with a later discontinuation of the ventilatory support, while the weaning process duration was shorter than before protocol implementation.
背景:对儿科重症监护室收治的支气管炎婴儿进行护士驱动的呼吸支持中止方案评估:对儿科重症监护室收治的支气管炎婴儿停止呼吸支持的护士驱动方案进行评估:方法:在一家三级医疗中心进行一项回顾性单中心研究,采用前后对比设计:共纳入 187 名婴儿(95 名采用标准方案,92 名采用护士驱动方案)。两个阶段的断奶失败率没有差异(11 (12 %) 对 14 (15 %),p = 0.46)。在护士驱动方案期间,通气支持的中断时间较晚(44 小时(IQR 29-67)对 33 小时(IQR 19-46),p = 0.001),但断气过程持续时间比方案实施前短(24 小时(IQR 0-60 )对 39 小时(IQR 18-64),p = 0.01)。方案实施前后的总通气时间(不包括使用 BiPAP 的时间)相似(53 小时(IQR 37-81 小时)对 55 小时(IQR 28-81 小时),p = 0.46)。两个阶段的 PICU 和住院时间没有差异:结论:在使用无创呼吸支持的支气管炎患者中,护士主导的停用管理(而非医生主导)与较晚停用呼吸支持有关,而断奶过程持续时间比实施方案前更短。
{"title":"Impact of a nurse-driven noninvasive respiratory support discontinuation protocol in infants with severe bronchiolitis","authors":"Julie Cassibba ,&nbsp;Marie Chevallier ,&nbsp;Aurélie Alexandre ,&nbsp;Alice Fumagalli ,&nbsp;Brigitte Fauroux ,&nbsp;Guillaume Mortamet","doi":"10.1016/j.arcped.2024.08.006","DOIUrl":"10.1016/j.arcped.2024.08.006","url":null,"abstract":"<div><h3>Background</h3><div>To evaluate a nurse-driven respiratory support discontinuation protocol in infants with bronchiolitis admitted in paediatric intensive care units.</div></div><div><h3>Methods</h3><div>A retrospective single-center study with pre-versus-post comparative design in a tertiary center<em>.</em></div></div><div><h3>Results</h3><div>In total, 187 infants (95 with standard and 92 with nurse-driven protocols) were included. There was no difference in terms of weaning failure between the two periods (11 (12 %) <em>versus</em> 14 (15 %), <em>p</em> = 0.46). During the nurse-driven protocol period, discontinuation of the ventilatory support was performed later (at 44 hrs (IQR 29–67) <em>versus</em> 33 hrs (IQR 19–46), <em>p</em> = 0.001), but the weaning process duration was shorter than before protocol implementation (24 h (IQR 0–60) <em>versus</em> 39 (IQR 18–64), <em>p</em> = 0.01). The total duration of ventilation (excluding time on BiPAP) was similar before and after protocol (53 (IQR 37–81) <em>versus</em> 55 h (IQR 28–81), <em>p</em> = 0.46). The PICU and hospital lengths of stay did not differ between the two periods.</div></div><div><h3>Conclusions</h3><div>In patients with bronchiolitis supported by noninvasive respiratory support, the nurse-driven discontinuation management - as opposed to physician-driven – was associated with a later discontinuation of the ventilatory support, while the weaning process duration was shorter than before protocol implementation.</div></div>","PeriodicalId":55477,"journal":{"name":"Archives De Pediatrie","volume":"32 1","pages":"Pages 18-23"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Archives De Pediatrie
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1