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Implementation of a protocol to prevent hypoglycemia in at-risk neonates born at 35 weeks' gestational age in a tertiary hospital: Adherence and satisfaction. It's not so easy! 在一家三级医院实施预防胎龄 35 周高风险新生儿低血糖的方案:遵守情况和满意度。没那么容易
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2024-10-28 DOI: 10.1016/j.arcped.2024.07.008
Marion Suprin, Nathan Micheletti, Sylvie-Françoise Caraby, Cyril Ruello, Anne Ego, Thierry Debillon, Julia Doutau, Marie Chevallier

Background: The present study assessed adherence and satisfaction regarding a new protocol for preventing hypoglycemia in neonates, with a target of 80 % adherence.

Methods: This 6-month prospective observational study was conducted between 2021 and 2022 in a tertiary hospital maternity unit. Neonates with at least one hypoglycemia risk factor were included. Two factors for adherence were evaluated: feeding before 1 h of life and capillary blood glucose assay at 2 h of life.

Results: Protocol adherence was 67.6 % overall, with clinically satisfactory protocol application. Neonates small for gestational age were at the greatest risk of hypoglycemia (34.8 %). Non-adherence mainly concerned early feeding (28.9 %). The rate of hypoglycemia with adherence and non-adherence was, respectively, 15.8 % (n = 27/171) and 22.0 % (n = 18/82) (p = 0.23). Teams integrated the new recommendations successfully (satisfaction: 8/10), with some reluctance on the part of childcare assistants due to increased workload.

Conclusion: This apparently simple protocol could be supported by a quality improvement program. This study might help other care teams to establish similar protocols and identify areas for improvement.

背景本研究评估了预防新生儿低血糖新方案的依从性和满意度,目标是达到 80% 的依从性:这项为期 6 个月的前瞻性观察研究于 2021 年至 2022 年在一家三级医院的产科进行。研究纳入了至少有一个低血糖风险因素的新生儿。研究评估了遵守协议的两个因素:出生 1 小时前的喂养和出生 2 小时后的毛细血管血糖检测:结果:方案的总体依从性为 67.6%,临床应用效果令人满意。胎龄小的新生儿发生低血糖的风险最大(34.8%)。不遵守规定的情况主要涉及早期喂养(28.9%)。坚持和不坚持的低血糖发生率分别为 15.8 %(n = 27/171)和 22.0 %(n = 18/82)(p = 0.23)。团队成功地采纳了新建议(满意度:8/10),但儿童保育助理因工作量增加而有些不情愿:结论:这一看似简单的方案可以得到质量改进计划的支持。这项研究可能有助于其他护理团队制定类似的方案,并找出需要改进的地方。
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引用次数: 0
Paradigm shift in France in the medical care of children with genital development variations: Medical care for children with genital development variations in France. 法国对生殖器发育畸形儿童的医疗护理模式转变:法国对生殖器发育畸形儿童的医疗护理。
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2024-10-28 DOI: 10.1016/j.arcped.2024.07.009
Claire Bouvattier, Lise Duranteau, Tristan Verdelet, Marion Joly, Caroline Le Roux, Laurence Brunet

In 2021, for the first time, a legal framework organizing the care of children with a variation in genital development (VGD), sometimes referred to as "intersex children" or "children with differences in sex development" (DSD), was introduced in France (article L. 2131-6 of the Code of Public Health). It should be immediately apparent that the chosen term, "variation" rather than "anomalies" or "disorders" - which was previously used in the medical world - reflects a political will to renew both the way of thinking and the medical practices in this field. The aim of the new legal framework is to guarantee optimum care for children with VGD by requiring the systematic involvement of expert centers (to establish diagnoses and therapeutic proposals), providing the most comprehensive information possible to their families and seeking the minor's consent. Among the possible medical care options, the law explicitly mentions "therapeutic abstention," reflecting a paradigm shift aimed at curbing the too-frequent recourse to treatments whose sole objective is the conformation of the genitalia. An order was subsequently issued on 15 November 2022 to provide the necessary details for the implementation of the changes introduced by the law.

2021 年,法国首次出台了关于关爱生殖器发育变异儿童(VGD)的法律框架(《公共卫 生法》第 L.2131-6 条),生殖器发育变异儿童有时被称为 "双性儿童 "或 "性别发育差异儿 童"(DSD)。显而易见,选择 "变异 "一词而不是医学界以前使用的 "异常 "或 "失调",反映了在这一领域更新思维方式和医疗实践的政治意愿。新法律框架的目的是通过要求专家中心的系统参与(以确定诊断和治疗建议)、向其家人提供尽可能全面的信息以及征得未成年人的同意,来保证对患有 VGD 的儿童进行最佳治疗。在可能的医疗选择中,法律明确提到了 "放弃治疗",这反映了一种模式的转变,旨在遏制过于频繁地诉诸以生殖器整形为唯一目的的治疗。随后于 2022 年 11 月 15 日发布了一项命令,为实施该法律引入的变革提供了必要的细节。
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引用次数: 0
Managing child abuse or suspected child abuse in primary care: Results from a qualitative study of general practitioners trained in detecting child abuse: Managing child abuse or suspected child abuse in primary care. 在初级保健中处理虐待儿童或疑似虐待儿童问题:对接受过虐待儿童检测培训的全科医生进行定性研究的结果:在初级保健中处理虐待儿童或疑似虐待儿童问题。
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2024-10-27 DOI: 10.1016/j.arcped.2024.07.006
Maeva Jego, Camille De Lapeyrière, Mohamed Belhachemi, Didier Théry, Aurélie Janczewski

Introduction: Identifying and alerting suspected child abuse enables its investigation and management. In France, anyone can report the situation to child services when child abuse is suspected. However, the number of reports of concern received from physicians is low, and lack of knowledge is a frequent obstacle. This study aimed to explore the practices of trained general practitioners (GPs) regarding the identification and management of suspected child abuse.

Method: We led a qualitative study from February to November 2021 based on a grounded theory approach. We conducted semi-structured interviews with GPs working in the south of France who had received training in identifying child abuse. We performed an inductive analysis using NVivo software.

Results: We interviewed 10 GPs (data saturation with seventh GP). Despite the training, obstacles seemed to persist, such as apprehension of the parents' reaction, the technical difficulties of the process, and the lack of feedback after making a report. Being accompanied by a professional who can be directly contacted would facilitate the communication of worrying information. Without direct links to a single referent, doctors would prefer alternative ways of referring their patients to organizations they were familiar with.

Discussion and conclusion: GPs expressed a need for easy access to childcare professionals to support them in the decision to file a report of suspected child abuse. A multidisciplinary approach and a dedicated point of contact seemed to help the process. Nominating a child protection referent doctor per department and creating specific units in hospitals for children at risk would help GPs get effectual contacts for reporting worrying information and better care for children at risk of abuse.

导言:发现和提醒可疑的虐待儿童行为有助于对其进行调查和管理。在法国,任何人在怀疑儿童受到虐待时都可以向儿童服务机构报告。然而,从医生那里收到的报告数量却很少,而且缺乏相关知识也是一个常见的障碍。本研究旨在探讨经过培训的全科医生(GPs)在识别和处理疑似虐童事件方面的做法:我们于 2021 年 2 月至 11 月以基础理论方法开展了一项定性研究。我们对在法国南部工作、接受过识别虐待儿童培训的全科医生进行了半结构化访谈。我们使用 NVivo 软件进行了归纳分析:我们采访了 10 名全科医生(第七名全科医生的数据达到饱和)。尽管接受了培训,但障碍似乎依然存在,如对父母反应的担忧、处理过程中的技术难度以及报告后缺乏反馈等。如果有一位可以直接联系的专业人员陪同,将有助于沟通令人担忧的信息。如果不能直接联系到单一的转介人,医生更愿意选择其他方式将病人转介到他们熟悉的机构:讨论与结论:全科医生表示,他们需要方便地联系儿童保育专业人员,以支持他们做出报告疑似虐待儿童事件的决定。多学科方法和专门的联络点似乎有助于这一过程。在每个科室指定一名儿童保护推荐医生,并在医院设立专门负责高危儿童的部门,将有助于全科医生获得有效的联系方式,以报告令人担忧的信息,并更好地照顾面临虐待风险的儿童。
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引用次数: 0
Investigating the effect of peer-led educational intervention on behaviors related to pubertal health and its determinants in high school girls of Genaveh, Iran: Application of social cognitive theory. 调查同伴教育干预对伊朗 Genaveh 高中女生青春期健康相关行为及其决定因素的影响:社会认知理论的应用。
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2024-10-08 DOI: 10.1016/j.arcped.2024.05.001
Khadijeh Rezvani, Mohammad Hossein Kaveh, Leila Ghahramani, Abdolrahim Asadollahi

Background Empowering adolescents in the field of puberty health is one of the important goals of public health programs. The present study was carried out with the aim of determining the effect of peer-led training on puberty-related behavior and its determinants using social cognitive theory.

Methods: A total of 245 teenage girls were randomly divided into two groups: the intervention group and the comparison group. The questionnaire measuring puberty-related behavior and its determinants was self-administered and completed before and 2 months after training in the two groups. One session for parents, four sessions for peer educators, and four sessions for participants were conducted for 1 month.

Results: In the intervention group, unlike the comparison group, the mean scores of knowledge, outcome expectations, self-efficacy, self-control, social support, and behavior increased significantly after training (p <0.05). Based on regression analysis, outcome expectations and social support were the main determinants of puberty-related behavior (adjusted R2 = 0.464).

Conclusion: The findings of this study support the effectiveness of the peer-led educational intervention based on social cognitive theory in the improvement of puberty-related behavior and its determinants, which can be used in the design of puberty-related health promotion programs. Further research to assess the longer-term outcomes and to examine other theories of behavior change are suggested.

背景:增强青少年在青春期健康方面的能力是公共卫生项目的重要目标之一。本研究旨在利用社会认知理论确定同伴引导式培训对青春期相关行为及其决定因素的影响:共有 245 名少女被随机分为两组:干预组和对比组。两组分别在培训前和培训后 2 个月自填调查问卷,测量青春期相关行为及其决定因素。家长培训一次,同伴教育者培训四次,参与者培训四次,为期一个月:结果:与对比组不同,干预组的知识、结果预期、自我效能、自我控制、社会支持和行为的平均得分在培训后都有显著提高(P 2 = 0.464):本研究结果支持基于社会认知理论的同伴教育干预在改善青春期相关行为及其决定因素方面的有效性,可用于设计青春期相关健康促进计划。建议进一步开展研究,以评估长期结果并研究行为改变的其他理论。
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引用次数: 0
A new nonsense pathogenic variant in exon 1 of PHOX2B leads to the diagnosis of congenital central hypoventilation syndrome with intra-familial variability PHOX2B 外显子 1 中的一个新的无义致病变异导致先天性中枢通气不足综合征的诊断,且具有家族内变异性。
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2024-10-01 DOI: 10.1016/j.arcped.2024.06.003
Morgane Pelleter , Charlène Desaintjean , Romane Gyapay , Bruno Massenavette , Florent Baudin , Nathalie Couque , Renaud Tamisier , Benjamin Dudoignon , Patricia Franco , Antoine Mougenel-Chantereau , Laurianne Coutier
Congenital central hypoventilation syndrome (CCHS) is a rare genetic disorder of the autonomic nervous system resulting in decreased brain sensitivity to hypercapnia and hypoxia characterized by a genetic abnormality in the pair-like homeobox 2B (PHOX2B) gene. Most patients have a heterozygous expansion of the polyalanine repeat in exon 3 (PARM), while 10 % of patients have non-PARM (NPARM) mutations that can span the entire gene. The majority of pathogenic variants are de novo, but variants with incomplete penetrance can be identified in the heterozygous state. In the present report, CCHS was diagnosed in a symptomatic 3-month-old infant with neonatal respiratory distress. Genetic analysis revealed a new mutation in exon 1 of the PHOX2B gene – p.Ser28* (c.83C>G) – which was further identified in two family members, one minimally symptomatic and one asymptomatic. The identification of this new mutation supports the importance of sequencing the entire gene even when the classic PARM mutation is not found and highlights the phenotypic variability of CCHS.
先天性中枢通气不足综合征(CCHS)是一种罕见的自主神经系统遗传性疾病,会导致大脑对高碳酸血症和低氧血症的敏感性降低,其特征是对样同源染色体 2B (PHOX2B) 基因的遗传异常。大多数患者的第 3 号外显子(PARM)中的多丙氨酸重复序列发生杂合性扩增,而 10% 的患者则存在可跨越整个基因的非 PARM(NPARM)突变。大多数致病变异都是新发的,但在杂合状态下也能发现具有不完全渗透性的变异。在本报告中,一名有新生儿呼吸窘迫症状的 3 个月大婴儿被诊断为 CCHS。基因分析发现,PHOX2B 基因第 1 外显子中存在一个新的突变--p.Ser28* (c.83C>G),并在两个家族成员中进一步发现了这一突变,其中一人症状轻微,另一人无症状。这一新突变的发现证明,即使没有发现典型的 PARM 突变,对整个基因进行测序也是非常重要的,同时也凸显了 CCHS 的表型变异性。
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引用次数: 0
Neonatal screening: A public health success and the ethical dilemmas it can pose 新生儿筛查:公共卫生的成功及其可能带来的伦理困境。
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2024-10-01 DOI: 10.1016/j.arcped.2024.07.002
Brigitte Chabrol
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引用次数: 0
Exploring the relationship between social media use, sharenting practices, and maternal psychological well-being. 探索社交媒体使用、育儿实践与产妇心理健康之间的关系。
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2024-10-01 DOI: 10.1016/j.arcped.2024.04.008
Betül Orhan Kılıç, Serhat Kılıç, Betul Ulukol

Background: This study examined the correlation between social media usage, sharenting practices (sharing parenting-related content on social media), and psychological well-being among 130 mothers whose children visited Baskent University Hospital between April 2020 and January 2021.

Methods: The participants completed an online questionnaire that assessed their social media usage, sharenting practices on Instagram, as well as their levels of depression, life satisfaction, and psychological resilience. Additionally, the researchers created an Instagram account and followed the mothers' social media activities.

Results: The findings revealed that Instagram was the most commonly used social media platform, with mothers using it an average of 5.8 times per day and spending an average of 75 min per day on the platform. Sharing privacy-violating photos of their children was positively correlated with the mothers' own depressive symptoms (r = 0.285, p < 0.01) and negatively correlated with their life satisfaction (r=-0.274, p < 0.01). Similarly, sharing children's photos containing identifiable information was positively correlated with mothers' depressive symptoms (r = 0.373, p < 0.01) and negatively correlated with their life satisfaction (r=-0.282, p = 0.001).

Conclusion: These findings indicate a significant relationship between social media usage, sharenting practices, and the psychological well-being of mothers. The study underscores the importance of raising awareness about the potential risks associated with social media use, particularly among mothers who engage in sharenting practices.

研究背景本研究调查了在 2020 年 4 月至 2021 年 1 月期间有孩子在巴斯科特大学医院就诊的 130 名母亲中,社交媒体使用情况、分享行为(在社交媒体上分享育儿相关内容)与心理健康之间的相关性:参与者填写了一份在线问卷,该问卷评估了她们的社交媒体使用情况、在 Instagram 上分享育儿相关内容的行为,以及她们的抑郁程度、生活满意度和心理承受力。此外,研究人员还创建了一个 Instagram 账户,跟踪母亲们的社交媒体活动:研究结果显示,Instagram 是最常用的社交媒体平台,母亲们平均每天使用 5.8 次,平均每天在该平台上花费 75 分钟。分享侵犯子女隐私的照片与母亲自身的抑郁症状呈正相关(r=0.285,p < 0.01),与母亲的生活满意度呈负相关(r=-0.274,p < 0.01)。同样,分享含有可识别信息的子女照片与母亲的抑郁症状呈正相关(r=0.373,p < 0.01),与母亲的生活满意度呈负相关(r=-0.282,p = 0.001):这些研究结果表明,社交媒体的使用、养育子女的做法与母亲的心理健康之间存在重要关系。本研究强调了提高对社交媒体使用相关潜在风险的认识的重要性,尤其是对那些参与育儿实践的母亲而言。
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引用次数: 0
Disordered eating behaviors and associated factors in children and adolescents with type 1 diabetes 1 型糖尿病儿童和青少年的饮食紊乱行为及相关因素。
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2024-10-01 DOI: 10.1016/j.arcped.2024.04.006
Ebru Barsal Çetiner , Zeynep Donbaloğlu , Aynur İnan Yüksel , Berna Singin , Bilge Aydın Behram , Aynur Bedel , Mesut Parlak , Hale Tuhan

Object

As part of their treatment, patients with type 1 diabetes mellitus (DM) have to be very careful with what they eat and with their insulin doses. Therefore, the risk of eating disorders increases in this patient group. In this study, we aimed to determine the disordered eating behaviors of patients with type 1 DM and to evaluate the sociodemographic characteristics, diabetes care behaviors, and quality-of-life scale results that these behaviors may be related to.

Method

The sociodemographic characteristics and diabetes treatment data of 191 patients aged 9–18 years with type 1 DM were analyzed. The Pediatric Quality of Life Inventory (PedsQL), the PedsQL 3.0 Diabetes Module, and the Diabetes Eating Problem Survey-Revised (DEPS-R) were applied.

Results

The median DEPS-R score of the patients was 18 (19.00), and 44.5 % had a DEPS-R score above 20. A significant correlation was found between age, duration of diabetes, frequency of blood glucose measurement, hemoglobin A1c (HbA1c) level, body mass index standard deviation score (BMI-SDS), and DEPS-R score. There was no significant difference between girls and boys. Patients with a high DEPS-R score had low scores on the PedsQL and on the PedsQL 3.0 Diabetes Module.

Conclusion

The DEPS-R scale is a diabetes-specific, easy-to-use, and effective method for screening patients with type 1 DM for disordered eating behaviors. It can help prevent the progression of disordered eating behaviors to clinical eating disorders in patients with type 1 DM. It would be beneficial to use this scale as a routine screening, especially in clinics where access to a psychologist is not possible.
目的:作为治疗的一部分,1 型糖尿病(DM)患者必须非常注意饮食和胰岛素剂量。因此,这类患者出现饮食失调的风险也随之增加。本研究旨在确定 1 型糖尿病患者的饮食失调行为,并评估这些行为可能与之相关的社会人口学特征、糖尿病护理行为和生活质量量表结果:分析了 191 名 9-18 岁 1 型糖尿病患者的社会人口学特征和糖尿病治疗数据。应用儿科生活质量量表(PedsQL)、儿科生活质量量表 3.0 糖尿病模块和糖尿病饮食问题调查-修订版(DEPS-R):患者 DEPS-R 评分的中位数为 18 分(19.00),44.5% 的患者 DEPS-R 评分超过 20 分。年龄、糖尿病病程、血糖测量频率、血红蛋白 A1c(HbA1c)水平、体重指数标准偏差评分(BMI-SDS)与 DEPS-R 评分之间存在明显相关性。女孩和男孩之间没有明显差异。DEPS-R 得分高的患者在 PedsQL 和 PedsQL 3.0 糖尿病模块中的得分较低:DEPS-R量表是一种针对糖尿病、易于使用且有效的方法,可用于筛查1型糖尿病患者的饮食失调行为。它有助于防止 1 型糖尿病患者的饮食行为紊乱发展为临床饮食紊乱。将该量表作为常规筛查方法将大有裨益,尤其是在无法请到心理医生的诊所。
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引用次数: 0
Characteristics and predictors of outcome in children with severe acute bronchiolitis: A 10-yearexperience 严重急性支气管炎患儿的特征和预后因素:10年的经验。
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2024-10-01 DOI: 10.1016/j.arcped.2024.06.002
Samia Hamouda , Safa Khatrouch , Aida Borgi , Ahmed Hajji , Hanen Smaoui , Najla Ben Jaballah , Fatma Khalsi , Khadija Boussetta

Background

Severe acute bronchiolitis (SAB) can be life-threatening for infants and may be responsible for the congestion of intensive care units (ICU) during epidemics. We aimed to study the clinical and paraclinical characteristics of patients with SAB requiring a transfer to the ICU in order to examine their outcomes and to identify the predictors of a stay of ≥7 days and/or death.

Methods

This was a cross-sectional retrospective study including infants aged ≤12 months transferred to the ICU for their first episode of SAB between 1 January 2010 and 31 December 2019.

Results

We collected data on 380 patients with a median age of 1.75 months. They had a history of prematurity (20.53 %), low birth weight (18.68 %), parental atopy (12.89 %), and comorbidity (7.37 %, mainly congenital heart disease [5 %]). The leading cause of transfer was hypoxemia and increased oxygen requirements (49.73 %). The patients required mechanical ventilation (MV) in 63.42 % of the cases and noninvasive ventilation (NIV) in 67.63 %. NIV has supplanted MV over the years. Its use has increased from 40.4 % in 2010 to 96 % in 2019 compared with 83.84 % and 42 % for MV. A total of 14 (3.68 %) patients died. The independent predictors of a stay of ≥7 days and/or death were young age ≤2 months (p = 0.002), failure to thrive (p = 0.006), apnea (p = 0.045), dehydration (p = 0.018), the presence of biological inflammatory reaction (p = 0.002), isolation of respiratory syncytial virus (p < 0.001), and bacterial coinfection (p = 0.013).NIV was a protective factor (p < 0.001). A severity score ranging from 0 to 17 was established with an optimal cut-off value of 5 points.

Conclusion

Specific caution is needed in patients with these severity predictors. The generalization ofNIV in general pediatrics departments would improve SAB management and reduce transfers to the ICU.
背景:严重急性支气管炎(SAB)可危及婴儿的生命,并可能导致流行病期间重症监护病房(ICU)的拥挤。我们的目的是研究需要转入重症监护室的 SAB 患者的临床和辅助临床特征,以检查他们的预后,并确定住院时间超过 7 天和/或死亡的预测因素:这是一项横断面回顾性研究,研究对象包括2010年1月1日至2019年12月31日期间因首次发作SAB而转入重症监护室的年龄≤12个月的婴儿:我们收集了380名患者的数据,中位年龄为1.75个月。他们有早产史(20.53%)、低出生体重(18.68%)、父母有过敏史(12.89%)和合并症(7.37%,主要是先天性心脏病[5%])。转院的主要原因是低氧血症和氧需求增加(49.73%)。63.42%的患者需要机械通气(MV),67.63%的患者需要无创通气(NIV)。多年来,无创通气已取代了机械通气。其使用率从 2010 年的 40.4% 增加到 2019 年的 96%,而 MV 和 NIV 的使用率分别为 83.84% 和 42%。共有 14 名患者(3.68%)死亡。住院时间≥7天和/或死亡的独立预测因素是年龄小于2个月(p = 0.002)、发育不良(p = 0.006)、呼吸暂停(p = 0.045)、脱水(p = 0.018)、出现生物炎症反应(p = 0.002)、分离出呼吸道合胞病毒(p < 0.001)和细菌合并感染(p = 0.013)。严重程度评分范围为 0 至 17 分,最佳临界值为 5 分:结论:对于具有这些严重程度预测因素的患者,需要特别谨慎。在普通儿科普及 NIV 可以改善 SAB 的管理,减少转入重症监护室的情况。
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引用次数: 0
Interaction of the protective effect of breastfeeding and the aggravating effect of pacifier use in the occurrence of bronchiolitis in children 母乳喂养的保护作用与使用安抚奶嘴的加重作用在儿童支气管炎发病中的相互作用。
IF 1.3 4区 医学 Q3 PEDIATRICS Pub Date : 2024-10-01 DOI: 10.1016/j.arcped.2024.05.004
Laureen Martin , Amaïa Bainier , Estelle Darviot , Aude Forgeron , Laurent Sarthou , Anne-Claire Wagner , Thomas Blanchais , Thomas Brigly , Françoise Troussier , Bernard Branger

Background

Acute bronchiolitis affects around 30 % of infants each winter in France. Breastfeeding (BF) is described as being protective against acute lower respiratory infections in developing countries, but this effect is more difficult to demonstrate in industrialized countries. Moreover, the effect of using a pacifier in the occurrence of bronchiolitis is not clearly established. In this context, the aim of the study was to investigate the link between BF and the use of a pacifier in the occurrence of bronchiolitis in children under 1 year of age who presented to five pediatric emergency centers in Pays de la Loire, France.

Method

A questionnaire collecting data on diet, sociodemographic characteristics, and the reason for presentation was provided at the admission to pediatric emergency centers in five hospitals in Pays de Loire, France, between 2018 and 2020. Children with bronchiolitis were included in group 1, and children consulting for other reasons (except gastrointestinal infections or otitis) were included in group 2. Breastfeeding was classified as exclusive breastfeeding (EBF) and partial breastfeeding (PBF). Pacifier use was classified as frequent and during sleep or not used.

Results

The study included 671 children under 1 year of age, including 174 (25.8 %) who were admitted with bronchiolitis. In univariate analysis, a significantly smaller number of children in group 1 s were breastfed (EBF and PBF) at admission compared with children in group 2:21.8 % versus 32.8 %, respectively, (OR=0.57, 95 % CI: 0.38–0.86, p = 0.006); furthermore, children in group 1 used a pacifier more often than those in group 2: 84.5 % versus 75.8 % (OR=1.74, 95 % CI: 1.10–2.76, p = 0.017). In multivariate analysis, after adjusting for age, ongoing BF or EBF beyond 9 and 12 months of age remained a protective factor; however, the protective effect of BF disappeared with the introduction of a pacifier, and pacifier use was significantly associated with bronchiolitis.

Conclusion

The protective effect of BF against bronchiolitis was demonstrated independently of pacifier use. However, due to the strong association between pacifier use and bronchiolitis, the effect of BF weakened. The advice to be given to parents for BF and pacifier use is discussed.
背景介绍在法国,每年冬季约有 30% 的婴儿患有急性支气管炎。在发展中国家,母乳喂养(BF)对急性下呼吸道感染有保护作用,但在工业化国家却很难证明这种作用。此外,使用安抚奶嘴对支气管炎发生的影响尚未得到明确证实。有鉴于此,本研究旨在调查在法国卢瓦尔河地区五家儿科急救中心就诊的 1 岁以下儿童支气管炎的发生与婴儿肥胖和使用安抚奶嘴之间的关系:2018年至2020年期间,法国卢瓦尔河地区五家医院的儿科急救中心在收治儿童时发放了一份调查问卷,收集了有关饮食、社会人口特征和发病原因的数据。支气管炎患儿被纳入第一组,因其他原因就诊的患儿(胃肠道感染或中耳炎除外)被纳入第二组。 母乳喂养分为纯母乳喂养(EBF)和部分母乳喂养(PBF)。安抚奶嘴的使用分为经常使用、睡眠中使用和不使用:研究包括 671 名 1 岁以下儿童,其中 174 名(25.8%)因支气管炎入院。在单变量分析中,入院时母乳喂养(EBF 和 PBF)的第 1 组儿童明显少于第 2 组儿童:分别为 21.8% 对 32.8%(OR=0.57,95% CI:0.38-0.86,p = 0.006);此外,第 1 组儿童使用安抚奶嘴的频率高于第 2 组儿童:分别为 84.5% 对 75.8%(OR=1.74,95% CI:1.10-2.76,p = 0.017)。在多变量分析中,对年龄进行调整后,9 个月和 12 个月以上的持续婴儿喂养或 EBF 仍是一个保护因素;但是,婴儿喂养的保护作用在使用安抚奶嘴后消失,而使用安抚奶嘴与支气管炎显著相关:结论:婴儿喂养对支气管炎的保护作用不受使用奶嘴的影响。然而,由于使用安抚奶嘴与支气管炎之间存在密切联系,婴儿喂养的效果有所减弱。本文讨论了在婴儿喂养和使用安抚奶嘴方面应向父母提出的建议。
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Archives De Pediatrie
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