Configurations最新文献

Mathematics has been called “the queen of the sciences,” yet studies of mathematics and literature have been comparatively rare in Configurations. While Project Muse reports over 500 hits for technology in Configurations, math appears in only 26 articles, not counting reviews or bibliographies. In order to identify how mathematics has figured into the field of science, literature, and the arts, this paper reviews all Configurations articles about mathematics and identifies vibrant themes and issues within that archive. Blending historiographical review with bibliographic analysis, we explore whether math and literature can be considered a subfield of science and literature, and what areas have been the most fruitful for inquiry thus far. We also look to discussions of mathematics and literature outside Configurations to determine where there might be opportunities to develop more trans-disciplinary conversations about mathematics and literature. By tracing the history of mathematics in Configurations, the paper chronicles a history of critical thinking about mathematics that helps illuminate our own discipline and its intersections with other forms of science studies. This disciplinary history can serve as an important interlocutor for science and literature scholars. By contextualizing Configurations articles about mathematics within this broader intellectual tradition, we identify areas for future research that could bring math more into alignment with other disciplines that have been better represented within the field of science, literature, and the arts.

Background: In 2018, a new system was proposed for classifying and reporting post-treatment adult brain tumor on magnetic resonance imaging, named as Brain Tumor Reporting and Data System (BT-RADS), that needs a validation by means of agreement studies.

Methods: A retrospective study was designed with the aim of identifying contrast-enhanced magnetic resonance imaging (MRI) of adult patients on follow-up for primary brain tumor at Fondazione Policlinico Campus Bio-Medico. Four radiologists (2 radiology residents, 1 general radiologist, 1 neuroradiologist) read and scored each study using the BT-RADS scoring tool, blinded to the MRI original report. Interobserver agreement and Fleiss' k were calculated to assess the level of diagnostic agreement. It was assessed how many times the assignment of different scoring of BT-RADS would have led to a different patient management.

Results: The total number of patients included in the study was 23 with 147 MRIs and a total of 588 BT-RADS scores retrospectively evaluated. The two most frequent tumor types were astrocytoma grade 4 (62%) and oligodendroglioma grade 3 (21%). The overall agreement rate for all 4 radiologists was 82% with a Fleiss' k of 0.70. The overall agreement rate between general radiologist and neuroradiologist was 91% with a Fleiss' k of 0.86. The overall agreement rate between 2 radiology residents and neuroradiologist was 80% with a Fleiss' k of 0.66. Astrocytoma grade 3 (k: 0.51) and oligodendroglioma grade 2 (k: 0.32) showed a poor agreement while higher values of agreement were found for astrocytoma grade 4 (k: 0.70), astrocytoma grade 2 (k: 0.78) and oligodendroglioma grade 3 (k: 0.78). All the radiologists agreed on BT-RADS assignment in 70% patients, three radiologists agreed in 17% and two radiologists agree in 13%. In no cases there was a complete disagreement among the readers. In 18% of cases the discrepancy in the estimated BT-RADS would have led to a different follow-up management.

Conclusions: BT-RADS can be considered a valid tool for neuroradiologists and radiologists even with little experience in the interpretation of patients' images during follow-up for adult primary brain tumors supporting standardized interpretation, reporting and clinical management.