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Journal of Cultural Cognitive Science最新文献

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Suppression, reappraisal, and acceptance of emotions: a comparison between Turkish immigrant and German adolescents 情绪的压抑、重评与接纳:土耳其移民与德国青少年之比较
IF 1.8 Q4 PSYCHOLOGY, EXPERIMENTAL Pub Date : 2019-06-01 DOI: 10.1007/s41809-019-00031-7
Iryna Voswinckel, Simone Spranz, N. Langguth, U. Stangier, C. Gawrilow, R. Steil
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引用次数: 2
When eye fixation might not reflect online ambiguity resolution in the visual-world paradigm: structural priming following multiple primes in Portuguese 当注视可能不反映视觉世界范式中的在线歧义解决:葡萄牙语多重启动后的结构启动
IF 1.8 Q4 PSYCHOLOGY, EXPERIMENTAL Pub Date : 2019-04-10 DOI: 10.1007/s41809-019-00021-9
Eunice G. Fernandes, Moreno I. Coco, H. Branigan
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引用次数: 1
Visual recycling and intertextuality: a neurocognitive perspective 视觉循环和互文性:神经认知视角
IF 1.8 Q4 PSYCHOLOGY, EXPERIMENTAL Pub Date : 2019-03-22 DOI: 10.1007/s41809-019-00020-w
A. Abdel-Raheem
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引用次数: 0
Immorality and bu daode, unculturedness and bu wenming 不道德和没有道德,没有文化和没有文明
IF 1.8 Q4 PSYCHOLOGY, EXPERIMENTAL Pub Date : 2018-08-11 DOI: 10.1007/s41809-018-0013-y
V. Dranseika, Renatas Berniūnas, Vytis Silius
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引用次数: 12
Editorial 社论
IF 1.8 Q4 PSYCHOLOGY, EXPERIMENTAL Pub Date : 2017-05-01 DOI: 10.1055/s-0036-1595586
F. Huettig, R. K. Mishra, P. Padakannaya
Rund zwei Drittel aller Kliniken waren bereits Opfer eines Hackerangriffs. Und obwohl die Nachfrage nach Cyberversicherungen rasant gestiegen ist, zögern viele Kliniken immer noch mit dem Abschluss – denn der Markt ist unübersichtlich. Erfahren Sie außerdem in der aktuellen Branche kompakt, wie sich Krankenhausbaumaßnahmen abseits der Investitionsfinanzierungen durch das KHG finanzieren lassen und warum sich Krankenversicherungen zukünftig stärker darauf fokussieren sollten, Gesunde zu unterstützen.
大约三分之二的诊所都是黑客袭击的受害者。虽然网络保险需求飞涨,但许多诊所仍然犹豫不决,因为市场实在是不可预测。此外,在英国医药行业,你还可以了解如何用全行业投资融资之外的医院建设措施,以及为什么医疗保险公司未来要更加关注支持健康发展。
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引用次数: 0
The quantum metaphor and the organization of words in the mind 量子隐喻和思维中的语言组织
IF 1.8 Q4 PSYCHOLOGY, EXPERIMENTAL Pub Date : 2017-03-17 DOI: 10.1007/s41809-017-0003-5
G. Libben
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引用次数: 14
Integrating brain, cognition and culture 整合大脑、认知和文化
IF 1.8 Q4 PSYCHOLOGY, EXPERIMENTAL Pub Date : 2017-02-17 DOI: 10.1007/s41809-017-0001-7
M. Posner, M. Rothbart
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引用次数: 9
Invariant TAD Boundaries Constrain Cell-Type-Specific Looping Interactions between Promoters and Distal Elements around the CFTR Locus. 不变的 TAD 边界制约着 CFTR 基因座周围的启动子和远端元件之间的细胞类型特异性循环相互作用。
IF 1.3 Q4 PSYCHOLOGY, EXPERIMENTAL Pub Date : 2016-01-07 DOI: 10.1016/j.ajhg.2015.12.002
Emily M Smith, Bryan R Lajoie, Gaurav Jain, Job Dekker

Three-dimensional genome structure plays an important role in gene regulation. Globally, chromosomes are organized into active and inactive compartments while, at the gene level, looping interactions connect promoters to regulatory elements. Topologically associating domains (TADs), typically several hundred kilobases in size, form an intermediate level of organization. Major questions include how TADs are formed and how they are related to looping interactions between genes and regulatory elements. Here we performed a focused 5C analysis of a 2.8 Mb chromosome 7 region surrounding CFTR in a panel of cell types. We find that the same TAD boundaries are present in all cell types, indicating that TADs represent a universal chromosome architecture. Furthermore, we find that these TAD boundaries are present irrespective of the expression and looping of genes located between them. In contrast, looping interactions between promoters and regulatory elements are cell-type specific and occur mostly within TADs. This is exemplified by the CFTR promoter that in different cell types interacts with distinct sets of distal cell-type-specific regulatory elements that are all located within the same TAD. Finally, we find that long-range associations between loci located in different TADs are also detected, but these display much lower interaction frequencies than looping interactions within TADs. Interestingly, interactions between TADs are also highly cell-type-specific and often involve loci clustered around TAD boundaries. These data point to key roles of invariant TAD boundaries in constraining as well as mediating cell-type-specific long-range interactions and gene regulation.

三维基因组结构在基因调控中发挥着重要作用。从整体上看,染色体分为活跃区和非活跃区,而在基因水平上,循环相互作用将启动子与调控元件连接起来。拓扑关联域(TADs)通常有几百千个碱基大小,构成了中间层次的组织。主要的问题包括 TADs 是如何形成的,以及它们与基因和调控元件之间的环状相互作用有什么关系。在这里,我们在一组细胞类型中对围绕 CFTR 的 2.8 Mb 7 号染色体区域进行了集中的 5C 分析。我们发现所有细胞类型中都存在相同的 TAD 边界,这表明 TAD 代表了一种普遍的染色体结构。此外,我们还发现这些 TAD 边界的存在与位于它们之间的基因的表达和循环无关。相反,启动子和调控元件之间的循环相互作用具有细胞类型的特异性,并且主要发生在 TADs 内。CFTR 启动子就是一个例子,在不同的细胞类型中,它与不同的远端细胞类型特异性调控元件相互作用,而这些元件都位于同一个 TAD 中。最后,我们发现位于不同 TAD 中的基因座之间也存在长程关联,但其相互作用频率远低于 TAD 内的循环相互作用。有趣的是,TADs 之间的相互作用也具有高度的细胞类型特异性,而且往往涉及围绕 TAD 边界聚集的基因座。这些数据表明,不变的 TAD 边界在限制和介导细胞类型特异性长程相互作用和基因调控方面起着关键作用。
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引用次数: 0
期刊
Journal of Cultural Cognitive Science
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