Pub Date : 2023-10-04DOI: 10.23886/ejki.11.471.163-9
Irma Nareswari, Fransisca Pekerti, Sri Wahdini
Banyak faktor yang mempengaruhi timbulnya sindrom fibromialgia yang mengakibatkan pengobatan fibromialgia harus dilakukan secara holistik dan komprehensif. Terapi akupunktur merupakan salah satu terapi non farmakologis yang direkomendasikan oleh European Alliance of Associations for Rheumatology (EULAR). Tinjauan kasus berbasis bukti ini disusun untuk mengkaji efektivitas akupunktur terhadap penurunan intensitas nyeri dan perbaikan kualitas hidup pasien fibromialgia. Pencarian dilakukan di dua basis data yaitu PubMed dan Scopus. Kata kunci yang digunakan adalah “acupuncture”, “acupuncture therapy”, “fibromyalgia”, “fatigue syndrome, chronic”, “pain intensity”, “pain severity”. Telaah kritis dilakukan sesuai dengan panduan dari University of Oxford Centre for Evidence-based Medicine. Didapatkan empat artikel yang sesuai dengan pertanyaan klinis. Terapi akupunktur secara signifikan menunjukkan perbaikan kualitas hidup pasien fibromialgia serta menurunkan intensitas nyeri dengan efek samping yang minimal. Terapi akupunktur dapat menjadi salah satu pilihan terapi non farmakologis yang memberikan efek yang baik untuk memperbaiki nyeri serta meningkatkan kualitas hidup pasien fibromialgia.
{"title":"Efektivitas Terapi Akupunktur terhadap Penurunan Intensitas Nyeri dan Perbaikan Kualitas Hidup Pasien Fibromialgia","authors":"Irma Nareswari, Fransisca Pekerti, Sri Wahdini","doi":"10.23886/ejki.11.471.163-9","DOIUrl":"https://doi.org/10.23886/ejki.11.471.163-9","url":null,"abstract":"Banyak faktor yang mempengaruhi timbulnya sindrom fibromialgia yang mengakibatkan pengobatan fibromialgia harus dilakukan secara holistik dan komprehensif. Terapi akupunktur merupakan salah satu terapi non farmakologis yang direkomendasikan oleh European Alliance of Associations for Rheumatology (EULAR). Tinjauan kasus berbasis bukti ini disusun untuk mengkaji efektivitas akupunktur terhadap penurunan intensitas nyeri dan perbaikan kualitas hidup pasien fibromialgia. Pencarian dilakukan di dua basis data yaitu PubMed dan Scopus. Kata kunci yang digunakan adalah “acupuncture”, “acupuncture therapy”, “fibromyalgia”, “fatigue syndrome, chronic”, “pain intensity”, “pain severity”. Telaah kritis dilakukan sesuai dengan panduan dari University of Oxford Centre for Evidence-based Medicine. Didapatkan empat artikel yang sesuai dengan pertanyaan klinis. Terapi akupunktur secara signifikan menunjukkan perbaikan kualitas hidup pasien fibromialgia serta menurunkan intensitas nyeri dengan efek samping yang minimal. Terapi akupunktur dapat menjadi salah satu pilihan terapi non farmakologis yang memberikan efek yang baik untuk memperbaiki nyeri serta meningkatkan kualitas hidup pasien fibromialgia.","PeriodicalId":55771,"journal":{"name":"Journal Kedokteran Indonesia","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135645961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-11DOI: 10.23886/ejki.11.335.126-32
Putri Anggilina Manullang, Muhammad Arfiza Putra Saragih, Adlin Adnan, Ester Lantika Ronauli Silaen
Obstructive Sleep Apnea (OSA) merupakan obstruksi saluran napas atas saat tidur yang mengakibatkan penurunan saturasi oksigen. Di Indonesia, data prevalensi OSA masih sangat minim. Dari beberapa alat penapisan OSA, hanya BQ dan ESS yang memiliki versi Bahasa Indonesia, sementara STOP-Bang belum terdapat versi Bahasa Indonesia. Melakukan penapisan terhadap tanda dan gejala sangat penting dalam proses perencanaan dan evaluasi. Suatu alat ukur harus memenuhi unsur psikometrik dan mampu menyesuaikan dengan karakteristik sosial dan budaya setempat. Untuk menghasilkan alat ukur kuesioner STOP-Bang versi Indonesia dengan metode adaptasi lintas budaya yang reliabel dan tervalidasi. Penelitian ini merupakan penelitian observasional analitik menggunakan metode cross sectional. Setelah kuesioner STOP-Bang diadaptasikan ke Indonesia, kuesioner diberikan kepada 500 orang masyarakat Indonesia, kemudian setelah 14 hari akan dilakukan pengisian ulang terhadap 20 responden. Penelitian dilakukan pada bulan Juli sampai September 2023 di Kota Medan dan Binjai. Pengambilan sampel memakai metode purposive sampling. Dari 500 responden penelitian dan validitas diolah menggunakan Spearman correlation didapatkan (p<0.001 dan r=0.422±0.118) berarti ada korelasi bermakna dan cukup valid. Analisis reliabilitas menggunakan Cronbach’s-alpha (r=0,694) dan nilai Interclass Correlation Coefficient menggunakan Spearman correlation coefficient (r=0,886). Adaptasi lintas budaya kuesioner STOP-Bang versi Indonesia memiliki nilai validitas dan reliabilitas yang baik.
{"title":"Adaptasi Lintas Budaya Kuesioner STOP-Bang Versi Indonesia","authors":"Putri Anggilina Manullang, Muhammad Arfiza Putra Saragih, Adlin Adnan, Ester Lantika Ronauli Silaen","doi":"10.23886/ejki.11.335.126-32","DOIUrl":"https://doi.org/10.23886/ejki.11.335.126-32","url":null,"abstract":"Obstructive Sleep Apnea (OSA) merupakan obstruksi saluran napas atas saat tidur yang mengakibatkan penurunan saturasi oksigen. Di Indonesia, data prevalensi OSA masih sangat minim. Dari beberapa alat penapisan OSA, hanya BQ dan ESS yang memiliki versi Bahasa Indonesia, sementara STOP-Bang belum terdapat versi Bahasa Indonesia. Melakukan penapisan terhadap tanda dan gejala sangat penting dalam proses perencanaan dan evaluasi. Suatu alat ukur harus memenuhi unsur psikometrik dan mampu menyesuaikan dengan karakteristik sosial dan budaya setempat. Untuk menghasilkan alat ukur kuesioner STOP-Bang versi Indonesia dengan metode adaptasi lintas budaya yang reliabel dan tervalidasi. Penelitian ini merupakan penelitian observasional analitik menggunakan metode cross sectional. Setelah kuesioner STOP-Bang diadaptasikan ke Indonesia, kuesioner diberikan kepada 500 orang masyarakat Indonesia, kemudian setelah 14 hari akan dilakukan pengisian ulang terhadap 20 responden. Penelitian dilakukan pada bulan Juli sampai September 2023 di Kota Medan dan Binjai. Pengambilan sampel memakai metode purposive sampling. Dari 500 responden penelitian dan validitas diolah menggunakan Spearman correlation didapatkan (p<0.001 dan r=0.422±0.118) berarti ada korelasi bermakna dan cukup valid. Analisis reliabilitas menggunakan Cronbach’s-alpha (r=0,694) dan nilai Interclass Correlation Coefficient menggunakan Spearman correlation coefficient (r=0,886). Adaptasi lintas budaya kuesioner STOP-Bang versi Indonesia memiliki nilai validitas dan reliabilitas yang baik.","PeriodicalId":55771,"journal":{"name":"Journal Kedokteran Indonesia","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136023551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karies gigi adalah penyakit kronis jaringan keras gigi yang disebabkan oleh Streptococcus mutans (S.mutans). Berbagai metode termasuk aplikasi pasta gigi, senyawa antibakteri dan obat kumur yang mengandung fluoride bersama dengan penggunaan pemanis yang tidak dapat difermentasi seperti sorbitol telah disarankan untuk mengurangi aktivitas bakteri ini. Pada studi ekologi mulut telah mengkonfirmasi efektifitas bakteri probiotik dalam mengurangi jumlah S. mutans. Grain kefir merupakan salah satu produk probiotik. Tujuan penelitian ini adalah untuk melihat efektifitas grain kefir murni dan kombinasi dengan sorbitol terhadap pertumbuhan S. mutans secara in vitro. Penelitian dilakukan di laboratorium Biologi Oral Fakultas Kedokteran Gigi Universitas Brawijaya pada bulan Januari-Februari 2023. Dilakukan uji KHM (Konsentrasi Hambat Minimum) menggunakan uji tabung dan KBM (Konsentrasi Bakterisidal Minimum) menggunakan colony counter. Penentuan konstrasi perlakukan diawali dengan uji pendahuluan grain kefir murni konsentrasi 3,125% dan 6,25%, 12,5%, 25%, 50% dan 100%. Nilai KHM grain kefir murni uji pendahuluan terhadap S.mutans pada konsentrasi 12,5%. Pada konsentrasi perlakuan didapatkan nilai KHM grain kefir murni adalah 15% dan kombinasi grain kefir-sorbitol terhadap S.mutans yaitu pada konsentrasi 12,5%. Nilai KBM grain kefir murni didapatkan pada konsentrasi 15% dan kombinasi grain kefir-sorbitol pada konsentrasi 12,5%. Kombinasi grain kefir-sorbitol dapat menurunkan pertumbuhan S. mutans pada konsentrasi 12,5%.
{"title":"Studi In-Vitro Efektifitas Grain Kefir dengan Kombinasi Sorbitol Terhadap Pertumbuhan Streptococcus mutans","authors":"Viranda Sutanti, Yuanita Lely Rachmawati, Bintang Vallentino Nugraha Putra, Herlambang Pangestu","doi":"10.23886/ejki.11.259.156-62","DOIUrl":"https://doi.org/10.23886/ejki.11.259.156-62","url":null,"abstract":"Karies gigi adalah penyakit kronis jaringan keras gigi yang disebabkan oleh Streptococcus mutans (S.mutans). Berbagai metode termasuk aplikasi pasta gigi, senyawa antibakteri dan obat kumur yang mengandung fluoride bersama dengan penggunaan pemanis yang tidak dapat difermentasi seperti sorbitol telah disarankan untuk mengurangi aktivitas bakteri ini. Pada studi ekologi mulut telah mengkonfirmasi efektifitas bakteri probiotik dalam mengurangi jumlah S. mutans. Grain kefir merupakan salah satu produk probiotik. Tujuan penelitian ini adalah untuk melihat efektifitas grain kefir murni dan kombinasi dengan sorbitol terhadap pertumbuhan S. mutans secara in vitro. Penelitian dilakukan di laboratorium Biologi Oral Fakultas Kedokteran Gigi Universitas Brawijaya pada bulan Januari-Februari 2023. Dilakukan uji KHM (Konsentrasi Hambat Minimum) menggunakan uji tabung dan KBM (Konsentrasi Bakterisidal Minimum) menggunakan colony counter. Penentuan konstrasi perlakukan diawali dengan uji pendahuluan grain kefir murni konsentrasi 3,125% dan 6,25%, 12,5%, 25%, 50% dan 100%. Nilai KHM grain kefir murni uji pendahuluan terhadap S.mutans pada konsentrasi 12,5%. Pada konsentrasi perlakuan didapatkan nilai KHM grain kefir murni adalah 15% dan kombinasi grain kefir-sorbitol terhadap S.mutans yaitu pada konsentrasi 12,5%. Nilai KBM grain kefir murni didapatkan pada konsentrasi 15% dan kombinasi grain kefir-sorbitol pada konsentrasi 12,5%. Kombinasi grain kefir-sorbitol dapat menurunkan pertumbuhan S. mutans pada konsentrasi 12,5%.","PeriodicalId":55771,"journal":{"name":"Journal Kedokteran Indonesia","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136036884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-31DOI: 10.23886/ejki.11.214.181-8
Rahmat Cahyanur, Thariqah Salamah
Tulang merupakan salah satu organ yang sering menjadi lokasi metastasis kanker, misalnya kanker payudara, prostat, dan paru. Metastasis tulang berpotensi memicu peningkatan mortalitas dan morbiditas, serta penurunan kualitas hidup. Gejala dan tanda klinis metastasis tulang mencakup nyeri, fraktur patologis, hiperkalsemia, serta kompresi medula spinalis. Oleh karena itu, deteksi dini dan tata laksana metastasis tulang yang tepat diperlukan untuk mencegah komplikasi lebih lanjut. Pertimbangan dalam memilih modalitas pemeriksaan radiologi, sebagai langkah utama dalam diagnosis, harus dilakukan secara rasional berdasarkan lokasi lesi metastasis tulang. Selain itu, pemeriksaan alkalin fosfatase dan biopsi juga dapat menjadi pilihan pemeriksaan penunjang. Tata laksana metastasis tulang mencakup terapi suportif, seperti kontrol nyeri, pemberian bifosfonat, pemberian denosumab atau terapi sistemik, penggunaan radiofarmaka, dan kontrol lokal, yaitu radiasi eksterna atau pembedahan.
{"title":"Diagnosis dan Tata Laksana Metastasis Tulang","authors":"Rahmat Cahyanur, Thariqah Salamah","doi":"10.23886/ejki.11.214.181-8","DOIUrl":"https://doi.org/10.23886/ejki.11.214.181-8","url":null,"abstract":"Tulang merupakan salah satu organ yang sering menjadi lokasi metastasis kanker, misalnya kanker payudara, prostat, dan paru. Metastasis tulang berpotensi memicu peningkatan mortalitas dan morbiditas, serta penurunan kualitas hidup. Gejala dan tanda klinis metastasis tulang mencakup nyeri, fraktur patologis, hiperkalsemia, serta kompresi medula spinalis. Oleh karena itu, deteksi dini dan tata laksana metastasis tulang yang tepat diperlukan untuk mencegah komplikasi lebih lanjut. Pertimbangan dalam memilih modalitas pemeriksaan radiologi, sebagai langkah utama dalam diagnosis, harus dilakukan secara rasional berdasarkan lokasi lesi metastasis tulang. Selain itu, pemeriksaan alkalin fosfatase dan biopsi juga dapat menjadi pilihan pemeriksaan penunjang. Tata laksana metastasis tulang mencakup terapi suportif, seperti kontrol nyeri, pemberian bifosfonat, pemberian denosumab atau terapi sistemik, penggunaan radiofarmaka, dan kontrol lokal, yaitu radiasi eksterna atau pembedahan.","PeriodicalId":55771,"journal":{"name":"Journal Kedokteran Indonesia","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136036887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gallstone migration into the cystic duct aperture can prevent bile from exiting the gallbladder during contraction. Gallbladder wall strain increases due to a distinct form of pain (biliary colic). A more prolonged cystic duct obstruction can cause acute gallbladder inflammation (acute cholecystitis). Cholecystectomy is a popular treatment for gallstone-related illnesses. We present a 49-year-old male with heartburn, nausea, and vomiting for one month, worsening in the last week. On general examination, vital signs and urine output are expected. On clinical examination, he had tenderness on the upper right quadrant abdomen, and Murphy's sign was positive. An abdominal ultrasound (US) showed multiple cholelithiasis. The patient was performed elective laparoscopic cholecystectomy with pneumoperitoneum by Muyo hook. The patient was discharged on the third day after surgery. Recent research has highlighted this unusual method. In this unique and challenging situation, Muyo Hook may be an option.
{"title":"Pneumoperitoneum with Muyo Hook on Laparoscopic Cholecystectomy","authors":"Fadli Robby Amsriza, Rizka Fakhriani, Sagiran Sagiran","doi":"10.23886/ejki.11.205.170-4","DOIUrl":"https://doi.org/10.23886/ejki.11.205.170-4","url":null,"abstract":"Gallstone migration into the cystic duct aperture can prevent bile from exiting the gallbladder during contraction. Gallbladder wall strain increases due to a distinct form of pain (biliary colic). A more prolonged cystic duct obstruction can cause acute gallbladder inflammation (acute cholecystitis). Cholecystectomy is a popular treatment for gallstone-related illnesses. We present a 49-year-old male with heartburn, nausea, and vomiting for one month, worsening in the last week. On general examination, vital signs and urine output are expected. On clinical examination, he had tenderness on the upper right quadrant abdomen, and Murphy's sign was positive. An abdominal ultrasound (US) showed multiple cholelithiasis. The patient was performed elective laparoscopic cholecystectomy with pneumoperitoneum by Muyo hook. The patient was discharged on the third day after surgery. Recent research has highlighted this unusual method. In this unique and challenging situation, Muyo Hook may be an option.","PeriodicalId":55771,"journal":{"name":"Journal Kedokteran Indonesia","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136036883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-31DOI: 10.23886/ejki.11.254.143-8
Chalid Kurniawan, Bayu Ewangga, Mey M. Karyana
Kegiatan tatap layar yang lama akan meningkatkan kemungkinan terjadinya sindrom mata kering karena stabilitas komponen air mata berkurang. Penggunaan air mata buatan seperti diquafosol sodium dapat membantu mengatasi masalah mata kering. Tujuan penelitian adalah menilai perbedaan gejala subjektif dan tanda objektif mata kering pada kelompok pengguna diquafosol sodium sebelum melakukan kegiatan tatap layar dibandingkan kelompok kontrol. Penelitian ini menggunakan desain potong lingkang dengan subjek laki-laki muda 44 orang yang memenuhi kriteria inklusi dan tidak memenuhi kriteria eksklusi. Subjek dipilih secara acak kemudian dibagi dua kelompok. Penelitian dilakukan di Garut dari Oktober hingga Desember 2022. Dilakukan pemeriksaan Schirmer sebelum dan sesudah kegiatan tatap layar serta pengisian kuesioner mata kering. Kelompok intervensi mendapatkan diquafosol sodium sebelum kegiatan tatap layar sedangkan kelompok kontrol tidak mendapatkan. Data dianalisis dengan t-test atau Mann Whitney. Hasil penelitian menunjukkan terdapat perbedaan bermakna uji Schirmer setelah kegiatan tatap layar antar dua kelompok dan perbedaan bermakna hasil selisih uji Schirmer sebelum dan setelah kegiatan tatap layar. Analisis kuesioner menunjukkan hanya satu responden mengalami gejala mata kering pada kelompok intervensi dibandingkan 7 orang pada kelompok kontrol. Penelitian ini menunjukkan bahwa penggunaan air mata buatan diquafosol sodium efektif mencegah terjadinya sindrom mata kering sebelum kegiatan tatap layar.
{"title":"Efek Pemberian Tetes Mata Diquafosol Sodium 3% Sebelum Kegiatan Tatap Layar terhadap Kejadian Mata Kering pada Laki-laki Muda","authors":"Chalid Kurniawan, Bayu Ewangga, Mey M. Karyana","doi":"10.23886/ejki.11.254.143-8","DOIUrl":"https://doi.org/10.23886/ejki.11.254.143-8","url":null,"abstract":"Kegiatan tatap layar yang lama akan meningkatkan kemungkinan terjadinya sindrom mata kering karena stabilitas komponen air mata berkurang. Penggunaan air mata buatan seperti diquafosol sodium dapat membantu mengatasi masalah mata kering. Tujuan penelitian adalah menilai perbedaan gejala subjektif dan tanda objektif mata kering pada kelompok pengguna diquafosol sodium sebelum melakukan kegiatan tatap layar dibandingkan kelompok kontrol. Penelitian ini menggunakan desain potong lingkang dengan subjek laki-laki muda 44 orang yang memenuhi kriteria inklusi dan tidak memenuhi kriteria eksklusi. Subjek dipilih secara acak kemudian dibagi dua kelompok. Penelitian dilakukan di Garut dari Oktober hingga Desember 2022. Dilakukan pemeriksaan Schirmer sebelum dan sesudah kegiatan tatap layar serta pengisian kuesioner mata kering. Kelompok intervensi mendapatkan diquafosol sodium sebelum kegiatan tatap layar sedangkan kelompok kontrol tidak mendapatkan. Data dianalisis dengan t-test atau Mann Whitney. Hasil penelitian menunjukkan terdapat perbedaan bermakna uji Schirmer setelah kegiatan tatap layar antar dua kelompok dan perbedaan bermakna hasil selisih uji Schirmer sebelum dan setelah kegiatan tatap layar. Analisis kuesioner menunjukkan hanya satu responden mengalami gejala mata kering pada kelompok intervensi dibandingkan 7 orang pada kelompok kontrol. Penelitian ini menunjukkan bahwa penggunaan air mata buatan diquafosol sodium efektif mencegah terjadinya sindrom mata kering sebelum kegiatan tatap layar.","PeriodicalId":55771,"journal":{"name":"Journal Kedokteran Indonesia","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136036885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-31DOI: 10.23886/ejki.11.174.175-80
Mohammad Tegar Indrayana, Dedi Afandi, Ilhami Romus, Suri D. Lesmana
Severe malaria is a disease caused by Plasmodium falciparum as the main cause of death in malaria. As autopsy examinations on malaria are rare in Indonesia, we report a nineteen-year-old male from Dumai, Indonesia, who died of severe malaria on November 10th 2018, at Dumai Regional General Hospital of Riau Province. The diagnosis was concluded from autopsy, histopathology and toxicology. This case report aimed to explain autopsy findings in severe malaria. As the result of external examination, we found some bruises on the right earlobe, lip mucosa and lower leg; excoriations on the neck, both arms and right lower leg; excoriations on the right lower leg and blood infiltration in the connective tissue on the right intercostal space. The autopsy and histopathology examination showed signs of congestion and hemozoin pigment in the brain, small intestine, liver, lung, heart, kidney, stomach and spleen. On toxicology examination, there was no narcotic substance found. Based on autopsy findings, histopathology and toxicological findings, we conclude that the cause of death, in this case, was severe malaria. Blunt violence to the ears, lips, neck, arms, and legs did not significantly cause death.
{"title":"Autopsy Discoveries in Severe Malaria","authors":"Mohammad Tegar Indrayana, Dedi Afandi, Ilhami Romus, Suri D. Lesmana","doi":"10.23886/ejki.11.174.175-80","DOIUrl":"https://doi.org/10.23886/ejki.11.174.175-80","url":null,"abstract":"Severe malaria is a disease caused by Plasmodium falciparum as the main cause of death in malaria. As autopsy examinations on malaria are rare in Indonesia, we report a nineteen-year-old male from Dumai, Indonesia, who died of severe malaria on November 10th 2018, at Dumai Regional General Hospital of Riau Province. The diagnosis was concluded from autopsy, histopathology and toxicology. This case report aimed to explain autopsy findings in severe malaria. As the result of external examination, we found some bruises on the right earlobe, lip mucosa and lower leg; excoriations on the neck, both arms and right lower leg; excoriations on the right lower leg and blood infiltration in the connective tissue on the right intercostal space. The autopsy and histopathology examination showed signs of congestion and hemozoin pigment in the brain, small intestine, liver, lung, heart, kidney, stomach and spleen. On toxicology examination, there was no narcotic substance found. Based on autopsy findings, histopathology and toxicological findings, we conclude that the cause of death, in this case, was severe malaria. Blunt violence to the ears, lips, neck, arms, and legs did not significantly cause death.","PeriodicalId":55771,"journal":{"name":"Journal Kedokteran Indonesia","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136036722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-31DOI: 10.23886/ejki.11.264.102-8
Fasihah Irfani Fitri, Muhammad Zulfikri
Dyslipidemia is one of the main risk factors for both ischemic stroke and cognitive impairment. Atherogenic index of plasma (AIP) has been shown to correlate with mortality and clinical outcomes in stroke, but studies about its association with cognitive impairment in ischemic stroke is still limited. We aimed to determine the correlation between AIP and lipid profile and cognitive function and their effect on outcome in ischemic stroke patients. A cross-sectional study involving 50 ischemic stroke patients in the Haji Adam Malik General Hospital was conducted from August 2021 to March 2022. We measured the cholesterol level and calculated the AIP then divided them into 3 risk categories which were high (AIP>0.21); intermediate (AIP>0.11and ≤0.21) and low (≤0.11). We performed cognitive assessment and stroke outcome at the 7th day of stroke onset. Data analysis was conducted with Spearman correlation test. The subjects were predominantly male (60%) with median age of 55 (34-68) years. Most of the subjects had AIP level of high risk (54%) and were cognitively impaired (66%). There was no significant association between AIP and both global cognition and each cognitive domain. However, there were significant negative correlations between total cholesterol (r=-0.31, p=0.03) and LDL-C level (r=-0.30, p=0.03) and attention. There was also a significant negative correlation between cognitive function and stroke outcome (r=-0.61, p=0.01). Higher total cholesterol and LDL-C levels showed negative correlation with cognitive function, mainly attention. Poorer cognitive function correlated with worse outcome in ischemic stroke patients.
血脂异常是缺血性脑卒中和认知障碍的主要危险因素之一。血浆粥样硬化指数(AIP)已被证明与卒中的死亡率和临床结果相关，但其与缺血性卒中认知功能障碍的关联研究仍然有限。我们的目的是确定AIP与缺血性脑卒中患者血脂和认知功能的相关性及其对预后的影响。本研究于2021年8月至2022年3月对Haji Adam Malik综合医院的50例缺血性脑卒中患者进行了横断面研究。我们测量胆固醇水平并计算AIP，然后将他们分为3个高风险类别(AIP>0.21);中间(AIP>0.11和≤0.21)和低(≤0.11)。我们在卒中发生第7天进行认知评估和卒中结局。数据分析采用Spearman相关检验。受试者以男性为主(60%)，中位年龄55岁(34-68岁)。大多数受试者存在AIP高危水平(54%)和认知障碍(66%)。AIP与整体认知和各认知领域均无显著相关性。然而，总胆固醇(r=-0.31, p=0.03)和LDL-C水平(r=-0.30, p=0.03)与注意力呈显著负相关。认知功能与脑卒中预后也存在显著负相关(r=-0.61, p=0.01)。高总胆固醇和LDL-C水平与认知功能负相关，主要与注意力负相关。缺血性脑卒中患者认知功能差与预后差相关。
{"title":"Correlation between Atherogenic Index of Plasma and Lipid Profile with Cognitive Function and Their Effect on Outcome in Ischemic Stroke Patients","authors":"Fasihah Irfani Fitri, Muhammad Zulfikri","doi":"10.23886/ejki.11.264.102-8","DOIUrl":"https://doi.org/10.23886/ejki.11.264.102-8","url":null,"abstract":"Dyslipidemia is one of the main risk factors for both ischemic stroke and cognitive impairment. Atherogenic index of plasma (AIP) has been shown to correlate with mortality and clinical outcomes in stroke, but studies about its association with cognitive impairment in ischemic stroke is still limited. We aimed to determine the correlation between AIP and lipid profile and cognitive function and their effect on outcome in ischemic stroke patients. A cross-sectional study involving 50 ischemic stroke patients in the Haji Adam Malik General Hospital was conducted from August 2021 to March 2022. We measured the cholesterol level and calculated the AIP then divided them into 3 risk categories which were high (AIP>0.21); intermediate (AIP>0.11and ≤0.21) and low (≤0.11). We performed cognitive assessment and stroke outcome at the 7th day of stroke onset. Data analysis was conducted with Spearman correlation test. The subjects were predominantly male (60%) with median age of 55 (34-68) years. Most of the subjects had AIP level of high risk (54%) and were cognitively impaired (66%). There was no significant association between AIP and both global cognition and each cognitive domain. However, there were significant negative correlations between total cholesterol (r=-0.31, p=0.03) and LDL-C level (r=-0.30, p=0.03) and attention. There was also a significant negative correlation between cognitive function and stroke outcome (r=-0.61, p=0.01). Higher total cholesterol and LDL-C levels showed negative correlation with cognitive function, mainly attention. Poorer cognitive function correlated with worse outcome in ischemic stroke patients.","PeriodicalId":55771,"journal":{"name":"Journal Kedokteran Indonesia","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136036886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-31DOI: 10.23886/ejki.11.221.133-42
Yunianti Lafau, Nuri Purwito Adi, Amilya Agustina, Muhammad Ilyas, Agus Sugiharto
Psychosocial hazards are a major public health problem, so it is necessary to prevent and manage them so as not to cause mental and physical harm to workers. This study aims to determine changes in work stressors before and during the COVID-19 pandemic and related factors to workers in the PT.X Heavy equipment manufacturing industry. The study used a retrospective cohort design from 2018 and 2021 Medical Check-Up (MCU) data with a Stress Diagnosis Survey (SDS) questionnaire. Research was conducted from October 2021 until July 2022 with samples of 146 obtained. Bivariate analysis using proportion and mean test. The research found that the increase in moderate-severe stressors before and during the pandemic was role ambiguity, role conflict, quantitative workload, and career development. On the other hand, qualitative workloads and responsibility for others decreased during the pandemic. The most worsened was role ambiguity and responsibility for others. Based on the type of production and non-production work, there was a significant relationship to quantitative workload before the pandemic (p=0.043), and not significant during the pandemic. Furthermore, there is a significant relationship with qualitative workload during the pandemic (p = 0.043), and it was not significant before the pandemic. It can be concluded that the Pandemic conditions caused an increase and decrease in work stressors analysed in workers in the heavy equipment manufacturing industry.
{"title":"Work Stressors Before and During COVID-19 Pandemic and Factors Related to Workers in the Heavy Equipment Manufacturing Industry of PT.X","authors":"Yunianti Lafau, Nuri Purwito Adi, Amilya Agustina, Muhammad Ilyas, Agus Sugiharto","doi":"10.23886/ejki.11.221.133-42","DOIUrl":"https://doi.org/10.23886/ejki.11.221.133-42","url":null,"abstract":"Psychosocial hazards are a major public health problem, so it is necessary to prevent and manage them so as not to cause mental and physical harm to workers. This study aims to determine changes in work stressors before and during the COVID-19 pandemic and related factors to workers in the PT.X Heavy equipment manufacturing industry. The study used a retrospective cohort design from 2018 and 2021 Medical Check-Up (MCU) data with a Stress Diagnosis Survey (SDS) questionnaire. Research was conducted from October 2021 until July 2022 with samples of 146 obtained. Bivariate analysis using proportion and mean test. The research found that the increase in moderate-severe stressors before and during the pandemic was role ambiguity, role conflict, quantitative workload, and career development. On the other hand, qualitative workloads and responsibility for others decreased during the pandemic. The most worsened was role ambiguity and responsibility for others. Based on the type of production and non-production work, there was a significant relationship to quantitative workload before the pandemic (p=0.043), and not significant during the pandemic. Furthermore, there is a significant relationship with qualitative workload during the pandemic (p = 0.043), and it was not significant before the pandemic. It can be concluded that the Pandemic conditions caused an increase and decrease in work stressors analysed in workers in the heavy equipment manufacturing industry.","PeriodicalId":55771,"journal":{"name":"Journal Kedokteran Indonesia","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136036723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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