F. Sanni, O. Bartholomew, I. Conteh, Z. Gwa, A. Oyewande, O. Ajani, M. O. Dada, P. Abiodun, A. Yashim, M. Tomori, Afelumo Laide, Innocent Okwose, A. Bello
Background and objectives: Rotavirus is a significant cause of nonbacterial diarrhea, especially in infants and young children worldwide. This study evaluated the pattern of rotavirus infection in children under five years presenting with acute diarrhea in Abuja Teaching Hospital, Gwagwalada, Nigeria. Methodology: It was a cross-sectional descriptive study to describe the prevalence of rotavirus infection among children. The study enrolled children 1 to 59 months old with acute diarrhea attending General Paediatric Outpatient clinic and hospitalized in the Emergency Paediatric Unit of University of Abuja Teaching Hospital (UATH), Gwagwalada, Nigeria. Rotavirus antigen was detected in the stool by qualitative enzyme-linked immunosorbent assay (ELISA). Data were analyzed using IBM-SPSS version 25.0. Results: The study comprised of 414 diarrhoeal children aged 1–59 months, of which 226 (54.6%) were male and the mean age was 12.1 months. The overall rate of rotavirus infection was 43.0% (178/ 414). The rotavirus infection was slightly higher among females than in males (46.8% vs 39.8%; p=0.153). Children from upper and middle social classes were at 1.95 [CI=1.17–3.26] and 3.08[CI=1.77–5.34] times higher risks of rotavirus induced diarrhea than the children from the lower social class (p<0.005). Children whose mothers had post-secondary education were three times more at risk of rotavirus diarrhea [OR=3.70; CI=1.46–9.36] than those with primary or no formal education (p<0.05). Children who had never been vaccinated against rotavirus were four times more likely to suffer rotavirus infection than those who had been vaccinated [OR=3.96; 95%CI=1.13–13.89, p=0.032]. Conclusion: This study found that rotavirus was an important causative agent of diarrhea in children in Gwagwalada, Abuja. Due to low rotavirus vaccination status in children, rotavirus screening tests are necessary for children with acute diarrheal disease. J Med Sci. 2022; 16(2): 010. DOI: https://doi.org/10.55010/imcjms.16.020 *Correspondence: Felix Olaniyi Sanni, Department of Public Health, Fescosof Data Solutions, Ogun, Nigeria. Email: fescosofanalysis@gmail.com
{"title":"Prevalence of rotavirus infection \u0000among children under five years \u0000at a tertiary institution in Nigeria","authors":"F. Sanni, O. Bartholomew, I. Conteh, Z. Gwa, A. Oyewande, O. Ajani, M. O. Dada, P. Abiodun, A. Yashim, M. Tomori, Afelumo Laide, Innocent Okwose, A. Bello","doi":"10.55010/imcjms.16.020","DOIUrl":"https://doi.org/10.55010/imcjms.16.020","url":null,"abstract":"Background and objectives: Rotavirus is a significant cause of nonbacterial diarrhea, especially in infants and young children worldwide. This study evaluated the pattern of rotavirus infection in children under five years presenting with acute diarrhea in Abuja Teaching Hospital, Gwagwalada, Nigeria.\u0000\u0000Methodology: It was a cross-sectional descriptive study to describe the prevalence of rotavirus infection among children. The study enrolled children 1 to 59 months old with acute diarrhea attending General Paediatric Outpatient clinic and hospitalized in the Emergency Paediatric Unit of University of Abuja Teaching Hospital (UATH), Gwagwalada, Nigeria. Rotavirus antigen was detected in the stool by qualitative enzyme-linked immunosorbent assay (ELISA). Data were analyzed using IBM-SPSS version 25.0.\u0000\u0000Results: The study comprised of 414 diarrhoeal children aged 1–59 months, of which 226 (54.6%) were male and the mean age was 12.1 months. The overall rate of rotavirus infection was 43.0% (178/ 414). The rotavirus infection was slightly higher among females than in males (46.8% vs 39.8%; p=0.153). Children from upper and middle social classes were at 1.95 [CI=1.17–3.26] and 3.08[CI=1.77–5.34] times higher risks of rotavirus induced diarrhea than the children from the lower social class (p<0.005). Children whose mothers had post-secondary education were three times more at risk of rotavirus diarrhea [OR=3.70; CI=1.46–9.36] than those with primary or no formal education (p<0.05). Children who had never been vaccinated against rotavirus were four times more likely to suffer rotavirus infection than those who had been vaccinated [OR=3.96; 95%CI=1.13–13.89, p=0.032].\u0000\u0000Conclusion: This study found that rotavirus was an important causative agent of diarrhea in children in Gwagwalada, Abuja. Due to low rotavirus vaccination status in children, rotavirus screening tests are necessary for children with acute diarrheal disease.\u0000\u0000J Med Sci. 2022; 16(2): 010. DOI: https://doi.org/10.55010/imcjms.16.020\u0000*Correspondence: Felix Olaniyi Sanni, Department of Public Health, Fescosof Data Solutions, Ogun, Nigeria. Email: fescosofanalysis@gmail.com","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89014277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Md. Faizul Ahasan, Md. Ismail Khan, E. O. Eva, Rukhsana Quadir, Masuma Khanom, Syful Islam, S. Haque
Background and objectives: Non-steroidal anti-inflammatory drugs (NSAIDs) are the leading cause of peptic ulcer disease (PUD). Drug such as proton pump inhibitors or cytoprotective agents used to treat PUD have several adverse effects. Therefore, interest in alternative therapies like honey has increased due to fewer side effects, ease of accessibility and affordability. This study determined the anti-ulcer effect of natural honey against indomethacin induced ulcer in rats. Materials and Methods: This experimental study was conducted on albino rats. Rats were assigned to four groups (Group1 to 4) and each group consisted of six rats. Gr1 received indomethacin (60 mg/kg) only and Gr2, 3 and 4 were pre-treated with assigned doses of sucralfate, honey, and honey + sucralfate respectively for 7 days. The effects of experimental agents were assessed by ulcer score, ulcer index (UI), percentage protective ratio (PPR). Effect of honey, sucralfate and honey plus sucralfate mixture was compared against high dose indomethacin induced gastric ulcer in rats. Results: UI significantly (p < 0.001) reduced in sucralfate, (0.67 ± 0.82), honey (0.83 ± 0.98) and honey + sucralfate (0.17 ± 0.41) treated group compared to only indomethacin treated group (4 ± 0.63).The PPR of sucralfate, honey and honey + sucralfate was 83.25%, 79.25% and 95.75%, respectively. Conclusions: The study showed that honey had anti-ulcer properties against the indomethacin-induced gastric ulcers and the effect is potentiated when used with sucralfate. Honey may be used to protect the gastric mucosa against NSAIDs. IMC J Med Sci 2022; 16(2): 009. DOI: https://doi.org/10.55010/imcjms.16.019 *Correspondence: Md. Faizul Ahasan, Department of Pharmacology, Ibrahim Medical College, 1/A Ibrahim Sarani, Segunbagicha, Dhaka 1000, Bangladesh. Email: arronnoo_shuvro@live.com
{"title":"Anti-ulcer effects of natural honey against indomethacin induced gastric ulcer in rats","authors":"Md. Faizul Ahasan, Md. Ismail Khan, E. O. Eva, Rukhsana Quadir, Masuma Khanom, Syful Islam, S. Haque","doi":"10.55010/imcjms.16.019","DOIUrl":"https://doi.org/10.55010/imcjms.16.019","url":null,"abstract":"Background and objectives: Non-steroidal anti-inflammatory drugs (NSAIDs) are the leading cause of peptic ulcer disease (PUD). Drug such as proton pump inhibitors or cytoprotective agents used to treat PUD have several adverse effects. Therefore, interest in alternative therapies like honey has increased due to fewer side effects, ease of accessibility and affordability. This study determined the anti-ulcer effect of natural honey against indomethacin induced ulcer in rats.\u0000\u0000Materials and Methods: This experimental study was conducted on albino rats. Rats were assigned to four groups (Group1 to 4) and each group consisted of six rats. Gr1 received indomethacin (60 mg/kg) only and Gr2, 3 and 4 were pre-treated with assigned doses of sucralfate, honey, and honey + sucralfate respectively for 7 days. The effects of experimental agents were assessed by ulcer score, ulcer index (UI), percentage protective ratio (PPR). Effect of honey, sucralfate and honey plus sucralfate mixture was compared against high dose indomethacin induced gastric ulcer in rats.\u0000\u0000Results: UI significantly (p < 0.001) reduced in sucralfate, (0.67 ± 0.82), honey (0.83 ± 0.98) and honey + sucralfate (0.17 ± 0.41) treated group compared to only indomethacin treated group (4 ± 0.63).The PPR of sucralfate, honey and honey + sucralfate was 83.25%, 79.25% and 95.75%, respectively.\u0000\u0000Conclusions: The study showed that honey had anti-ulcer properties against the indomethacin-induced gastric ulcers and the effect is potentiated when used with sucralfate. Honey may be used to protect the gastric mucosa against NSAIDs.\u0000\u0000IMC J Med Sci 2022; 16(2): 009. DOI: https://doi.org/10.55010/imcjms.16.019\u0000\u0000*Correspondence: Md. Faizul Ahasan, Department of Pharmacology, Ibrahim Medical College, 1/A Ibrahim Sarani, Segunbagicha, Dhaka 1000, Bangladesh. Email: arronnoo_shuvro@live.com","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82505701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Prashanthkumar Goudappala, J. Sandhu, Vinay Krishnaiah, S. Palem
Background and objective: Nephropathy is the major cause of end-stage renal disease (ESRD) in type 2 diabetes mellitus (T2DM). Delay in identification and management of nephropathy in T2DM may cause development of ESRD. An increased level of serum ferritin plays a role in the pathogenesis of chronic kidney disease (CKD) in T2DM. Hence, the present study intended to assess the level of serum ferritin in renal dysfunction in patients with T2DM. Material and methods: This was a retrospective study with 81 T2DM patients with and without nephropathy. They were categorized into two groups. Group-1 consisted of 46 T2DM cases without nephropathy and remaining 35 with nephropathy.The clinical and biochemical parameters such as blood glucose, urea, creatinine, iron, ferritin, transferrin, total iron binding capacity (TIBC), and haemoglobin were measured by standard methods, and estimated glomerular filtration rate (eGFR) by MDRD formula. Results: Significantly (p<0.05) elevated level of serum ferritin along with urea and creatinine was found in patients with T2DM with nephropathy.A significant positive correlation (r = 0.37) of serum ferritin and negative correlation (r = - 0.852) of eGFR with creatinine were found. It indicated that ferritin could be a good marker to monitor kidney function in T2DM. Conclusion: Apart from eGFR and serum creatinine, raised serum ferritin level was a good indicator of renal dysfunction in T2DM patients and might play an important role in renal dysfunction in early stage diabetic nephropathy. IMC J Med Sci 2022; 16(2): 008. DOI: https://doi.org/10.55010/imcjms.16.018 *Correspondence: Dr. Siva Prasad Palem., M.Sc., Ph.D., Department of Biochemistry, Faculty of Medicine, Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar-505001, Telangana, India. Affiliated with Kaloji Narayana Rao University of Health Sciences (KNRUHS), Warangal, Telangana, India. E-mail: sp.biocom@yahoo.co.in.
{"title":"Serum ferritin level in type 2 diabetic patients with renal dysfunction","authors":"Prashanthkumar Goudappala, J. Sandhu, Vinay Krishnaiah, S. Palem","doi":"10.55010/imcjms.16.018","DOIUrl":"https://doi.org/10.55010/imcjms.16.018","url":null,"abstract":"Background and objective: Nephropathy is the major cause of end-stage renal disease (ESRD) in type 2 diabetes mellitus (T2DM). Delay in identification and management of nephropathy in T2DM may cause development of ESRD. An increased level of serum ferritin plays a role in the pathogenesis of chronic kidney disease (CKD) in T2DM. Hence, the present study intended to assess the level of serum ferritin in renal dysfunction in patients with T2DM.\u0000\u0000Material and methods: This was a retrospective study with 81 T2DM patients with and without nephropathy. They were categorized into two groups. Group-1 consisted of 46 T2DM cases without nephropathy and remaining 35 with nephropathy.The clinical and biochemical parameters such as blood glucose, urea, creatinine, iron, ferritin, transferrin, total iron binding capacity (TIBC), and haemoglobin were measured by standard methods, and estimated glomerular filtration rate (eGFR) by MDRD formula.\u0000\u0000Results: Significantly (p<0.05) elevated level of serum ferritin along with urea and creatinine was found in patients with T2DM with nephropathy.A significant positive correlation (r = 0.37) of serum ferritin and negative correlation (r = - 0.852) of eGFR with creatinine were found. It indicated that ferritin could be a good marker to monitor kidney function in T2DM.\u0000\u0000Conclusion: Apart from eGFR and serum creatinine, raised serum ferritin level was a good indicator of renal dysfunction in T2DM patients and might play an important role in renal dysfunction in early stage diabetic nephropathy.\u0000\u0000IMC J Med Sci 2022; 16(2): 008. DOI: https://doi.org/10.55010/imcjms.16.018\u0000\u0000*Correspondence: Dr. Siva Prasad Palem., M.Sc., Ph.D., Department of Biochemistry, Faculty of Medicine, Chalmeda Anand Rao Institute of Medical Sciences, Karimnagar-505001, Telangana, India. Affiliated with Kaloji Narayana Rao University of Health Sciences (KNRUHS), Warangal, Telangana, India. E-mail: sp.biocom@yahoo.co.in.","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87165086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sraboni Mazumder, F. Rahman, F. Akter, R. Khatun, S. Akter, S. Saha, Md. Shariful Alam Jilani, M. Sayeed, J. Haq
Background and objectives: The Helicobacter pylori infection rate varies according to the age, location of the residence and socioeconomic status. The aim of the present study was to investigate the status of H. pylori infection among the asymptomatic Bangladeshi rural children and adolescents. Material and methods: This cross-sectional study was carried out in a rural area under Pabna district about 150 km north-west of capital Dhaka. Asymptomatic and apparently healthy rural children and adolescents aged 6 to 18 years were enrolled in the study. A structured questionnaire was used to record the socio-demographic and clinical information. The rate of H. pylori infection was determined by the presence of H. pylori antigen in faeces and/or anti-H. pylori IgG and/or IgA antibodies in blood. H. pylori stool antigen was detected by lateral flow chromatographic immunoassay and serum anti-H. pylori IgG and IgA antibodies were estimated by ELISA method. Results: A total number of 185 asymptomatic and apparently healthy children and adolescents were enrolled of which 34, 131 and 20 were in 6-10, 11-15 and 16-18 years age groups respectively. The overall H. pylori infection rate was 79.5% (95% CI: 0.729, 0.85) by positive stool antigen or by the presence of serum anti-H. pylori IgG/IgA antibodies. The rate of H. pylori infection significantly (p=0.05) increased with progress of age. H. pylori infection rate was 67.6%, 80.2% and 95% in 6-10, 11-15 and 16-18 years age groups respectively. The concentration of serum anti-H. pylori IgG/IgA antibodies did not differ across the age groups. The infection rate was significantly (p<0.05) higher among the children of illiterate parents compared to the children of literate parents. Conclusion: The study demonstrated a high prevalence of H. pylori infection among children and adolescents in a rural setting. Gender and family history did not affect H. pylori prevalence but increasing age and poor educational status of parents were associated with a higher H. pylori prevalence. IMC J Med Sci 2022; 16(2): 007. DOI: https://doi.org/10.55010/imcjms.16.017 *Correspondence: J. Ashraful Haq, Department of Microbiology, Ibrahim Medical College, 1/A, Ibrahim Sarani, Segunbagicha, Dhaka 1000, Bangladesh. Email: jahaq54@yahoo.com
{"title":"Asymptomatic Helicobacter pylori infection among rural children and adolescents in Bangladesh","authors":"Sraboni Mazumder, F. Rahman, F. Akter, R. Khatun, S. Akter, S. Saha, Md. Shariful Alam Jilani, M. Sayeed, J. Haq","doi":"10.55010/imcjms.16.017","DOIUrl":"https://doi.org/10.55010/imcjms.16.017","url":null,"abstract":"Background and objectives: The Helicobacter pylori infection rate varies according to the age, location of the residence and socioeconomic status. The aim of the present study was to investigate the status of H. pylori infection among the asymptomatic Bangladeshi rural children and adolescents.\u0000\u0000Material and methods: This cross-sectional study was carried out in a rural area under Pabna district about 150 km north-west of capital Dhaka. Asymptomatic and apparently healthy rural children and adolescents aged 6 to 18 years were enrolled in the study. A structured questionnaire was used to record the socio-demographic and clinical information. The rate of H. pylori infection was determined by the presence of H. pylori antigen in faeces and/or anti-H. pylori IgG and/or IgA antibodies in blood. H. pylori stool antigen was detected by lateral flow chromatographic immunoassay and serum anti-H. pylori IgG and IgA antibodies were estimated by ELISA method.\u0000\u0000Results: A total number of 185 asymptomatic and apparently healthy children and adolescents were enrolled of which 34, 131 and 20 were in 6-10, 11-15 and 16-18 years age groups respectively. The overall H. pylori infection rate was 79.5% (95% CI: 0.729, 0.85) by positive stool antigen or by the presence of serum anti-H. pylori IgG/IgA antibodies. The rate of H. pylori infection significantly (p=0.05) increased with progress of age. H. pylori infection rate was 67.6%, 80.2% and 95% in 6-10, 11-15 and 16-18 years age groups respectively. The concentration of serum anti-H. pylori IgG/IgA antibodies did not differ across the age groups. The infection rate was significantly (p<0.05) higher among the children of illiterate parents compared to the children of literate parents.\u0000\u0000Conclusion: The study demonstrated a high prevalence of H. pylori infection among children and adolescents in a rural setting. Gender and family history did not affect H. pylori prevalence but increasing age and poor educational status of parents were associated with a higher H. pylori prevalence.\u0000\u0000IMC J Med Sci 2022; 16(2): 007. DOI: https://doi.org/10.55010/imcjms.16.017\u0000\u0000*Correspondence: J. Ashraful Haq, Department of Microbiology, Ibrahim Medical College, 1/A, Ibrahim Sarani, Segunbagicha, Dhaka 1000, Bangladesh. Email: jahaq54@yahoo.com","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73049467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Ikhtaire, N. Aurpa, N. Nahid, Syeda Shahdaty, T. Haq, K. Murshed, M. F. Rahaman
We report a case of a 26-year old lady who presented with a history of several episodes of limb weakness requiring repeated hospitalization over the last 12 years and about 6 years back, she also developed features of sicca complex. Further investigations revealed hypokalemia, distal renal tubular acidosis and bilateral extensive nephrocalcinosis. Finally, a diagnosis of Sjogren’s syndrome was made. Hypokalemia may be the presenting feature of Sjogren’s syndrome. Sjogren’s syndrome may be suspected in patients with recurrent hypokalemia and renal tubular acidosis. IMC J Med Sci 2022; 16(2): 004. DOI: https://doi.org/10.55010/imcjms.16.014 *Correspondence: Shapur Ikhtaire, Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka 1000, Bangladesh. Email: shapur17@gmail.com
{"title":"A case of Sjogren’s syndrome presenting with recurrent hypokalemia","authors":"S. Ikhtaire, N. Aurpa, N. Nahid, Syeda Shahdaty, T. Haq, K. Murshed, M. F. Rahaman","doi":"10.55010/imcjms.16.014","DOIUrl":"https://doi.org/10.55010/imcjms.16.014","url":null,"abstract":"We report a case of a 26-year old lady who presented with a history of several episodes of limb weakness requiring repeated hospitalization over the last 12 years and about 6 years back, she also developed features of sicca complex. Further investigations revealed hypokalemia, distal renal tubular acidosis and bilateral extensive nephrocalcinosis. Finally, a diagnosis of Sjogren’s syndrome was made. Hypokalemia may be the presenting feature of Sjogren’s syndrome. Sjogren’s syndrome may be suspected in patients with recurrent hypokalemia and renal tubular acidosis.\u0000\u0000IMC J Med Sci 2022; 16(2): 004. DOI: https://doi.org/10.55010/imcjms.16.014\u0000\u0000*Correspondence: Shapur Ikhtaire, Department of Internal Medicine, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka 1000, Bangladesh. Email: shapur17@gmail.com","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89841179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The current pandemic of COVID-19 has spread worldwide rapidly. Many countries are struggling with the third pandemic wave despite having the vaccine distribution to frontline workers and people at high risk. Several studies have suggested a high possibility of hospital-acquired COVID-19. Therefore, it is vital to have proper recommendations and guidelines to prevent COVID-19 transmission in hospitals. Eliminating hospital-acquired infection is impossible, but reducing the rate and severity is possible by following appropriate guidelines. This paper reviews the strategies and recommendations that can be helpful for a hospital authority to control and prevent SARS-CoV-2 infection among the patients and healthcare workers. IMC J Med Sci 2022; 16(2): 006. DOI: https://doi.org/10.55010/imcjms.16.016 *Correspondence: Akash Ahmed, Department of Mathematics & Natural Sciences, BRAC University, Dhaka, Bangladesh. Email: akash.ahmed@bracu.ac.bd
{"title":"Management strategy for control and prevention of SARS-CoV-2 infection in hospital settings - a brief review","authors":"I. Aftab, A. Ahmed, S. Mumu, M. M. Hossain","doi":"10.55010/imcjms.16.016","DOIUrl":"https://doi.org/10.55010/imcjms.16.016","url":null,"abstract":"The current pandemic of COVID-19 has spread worldwide rapidly. Many countries are struggling with the third pandemic wave despite having the vaccine distribution to frontline workers and people at high risk. Several studies have suggested a high possibility of hospital-acquired COVID-19. Therefore, it is vital to have proper recommendations and guidelines to prevent COVID-19 transmission in hospitals. Eliminating hospital-acquired infection is impossible, but reducing the rate and severity is possible by following appropriate guidelines. This paper reviews the strategies and recommendations that can be helpful for a hospital authority to control and prevent SARS-CoV-2 infection among the patients and healthcare workers.\u0000\u0000IMC J Med Sci 2022; 16(2): 006. DOI: https://doi.org/10.55010/imcjms.16.016\u0000\u0000*Correspondence: Akash Ahmed, Department of Mathematics & Natural Sciences, BRAC University, Dhaka, Bangladesh. Email: akash.ahmed@bracu.ac.bd","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"78 6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79948917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tracheal stenosis is an uncommon and dangerous complication after intubation and tracheostomy and its clinical presentation may be misinterpreted as bronchial asthma. A careful vigilant clinical history and examination is required for the diagnosis of such tracheal stenosis. Here, we describe a case of post intubation subglottic tracheal stenosis in a young male who presented with features mimicking bronchial asthma. IMC J Med Sci 2022; 16(2): 005. DOI: https://doi.org/10.55010/imcjms.16.015 *Correspondence: Bhupendra Kumar Jain, Department of Pulmonary Medicine, Chhindwara Institute of Medical Sciences, Chhindwara, Jabalpur Medical University, Madhya Pradesh, India; ORCID : 0000-0002-6619- 8596;Email: drbhupendrakjain@gmail.com
{"title":"A case of severe subglottic stenosis masking as bronchial asthma","authors":"Bhupendra Jain, U. Chandrakantham","doi":"10.55010/imcjms.16.015","DOIUrl":"https://doi.org/10.55010/imcjms.16.015","url":null,"abstract":"Tracheal stenosis is an uncommon and dangerous complication after intubation and tracheostomy and its clinical presentation may be misinterpreted as bronchial asthma. A careful vigilant clinical history and examination is required for the diagnosis of such tracheal stenosis. Here, we describe a case of post intubation subglottic tracheal stenosis in a young male who presented with features mimicking bronchial asthma.\u0000\u0000IMC J Med Sci 2022; 16(2): 005. DOI: https://doi.org/10.55010/imcjms.16.015\u0000\u0000*Correspondence: Bhupendra Kumar Jain, Department of Pulmonary Medicine, Chhindwara Institute of Medical Sciences, Chhindwara, Jabalpur Medical University, Madhya Pradesh, India; ORCID : 0000-0002-6619- 8596;Email: drbhupendrakjain@gmail.com","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91214650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Sultana, Amrit Rijal, Hurjahan Banu, S. Jahan, M. Fariduddin, B. P. Dey, M. Hasanat
Ectopic parathyroid adenoma sometimes poses diagnostic challenge and can be a cause of persistent and recurrent primary hyperparathyroidism. Anterior mediastinum is one of the locations for ectopic parathyroid adenoma. Surgical excision is the only cure and for successful surgery, pre-operative localization is crucial. Chance of failed surgery is being increased without prior localization of the ectopic gland. The combination of single photon emission computed tomography (SPECT) and computed tomography (CT) has got high sensitivity for accurate localization of ectopic parathyroid. On the other hand, with accurate localization surgical outcome is excellent. Here we report, successful localization and management of a case of primary hyperparathyroidism due to adenoma in anterior mediastinum in 47-year-old man. IMC J Med Sci 2022; 16(2): 003. DOI: https://doi.org/10.55010/imcjms.16.013 *Correspondence: Dr. Nusrat Sultana, Room no-1620, Block-D, 15th floor, Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. Email: nusrat_sultana@bsmmu.edu.bd
{"title":"Localization and management of mediastinal parathyroid adenoma – a case report","authors":"N. Sultana, Amrit Rijal, Hurjahan Banu, S. Jahan, M. Fariduddin, B. P. Dey, M. Hasanat","doi":"10.55010/imcjms.16.013","DOIUrl":"https://doi.org/10.55010/imcjms.16.013","url":null,"abstract":"Ectopic parathyroid adenoma sometimes poses diagnostic challenge and can be a cause of persistent and recurrent primary hyperparathyroidism. Anterior mediastinum is one of the locations for ectopic parathyroid adenoma. Surgical excision is the only cure and for successful surgery, pre-operative localization is crucial. Chance of failed surgery is being increased without prior localization of the ectopic gland. The combination of single photon emission computed tomography (SPECT) and computed tomography (CT) has got high sensitivity for accurate localization of ectopic parathyroid. On the other hand, with accurate localization surgical outcome is excellent. Here we report, successful localization and management of a case of primary hyperparathyroidism due to adenoma in anterior mediastinum in 47-year-old man.\u0000\u0000IMC J Med Sci 2022; 16(2): 003. DOI: https://doi.org/10.55010/imcjms.16.013\u0000\u0000*Correspondence: Dr. Nusrat Sultana, Room no-1620, Block-D, 15th floor, Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. Email: nusrat_sultana@bsmmu.edu.bd","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89410689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background and objectives: Skull base fractures have high mortality and morbidity rates and constitute a significant medical issue. The aim of the present study was to review the demographic characteristics, common locations and causes of the skull base fractures retrospectively. Methods: This retrospective study was conducted on patients who attended the Intensive Care Unit/Radiology Clinic of Adiyaman University Training and Research Hospital between 2015 and 2018 and were found to have skull base fractures. The data were accessed via PACS system of the hospital database. Age, gender, cause of the trauma, type of the skull base fracture, imaging findings and outcome of the enrolled patients were analyzed. Results: Total 138 cases who met the study criteria were enrolled in the study. The causes of the skull base fracture were as follows: fall 52.2%, traffic accident 36.2%, pounding 3.6%, firearm injury 0.7%, sharp object injury 0.7%, and other causes 6.5%. There was a statistically significant (p<0.001) difference in rate of skull base fracture caused by traffic accident between the ≤18-year group and 19-45 age group. The difference between the types of epidural hematoma was not significant in all age groups (p= 0.156); however, there was a statistically significant difference for gender (female vs. male 26.1%73.9%, p=0.025). Conclusion: Skull base fractures were more common in fall from height and traffic accidents. In order to reduce skull base fractures, it is recommended to take preventive precautions for falls from height and traffic accidents. IMC J Med Sci 2022; 16(2): 002. DOI:https://doi.org/10.55010/imcjms.16.012 *Correspondence: Safiye Kafadar, Department of Radiology, Adiyaman University Education and Research Hospital, Adiyaman, Turkey. Email: safiyekafadar@gmail.com, ORCID: 0000-0003-4070-9615
{"title":"A retrospective analysis of the skull base fractures: demographic characteristics, causes and imaging findings","authors":"H. Kafadar, S. Kafadar, Ş. Yücetaş, H. Kaya","doi":"10.55010/imcjms.16.012","DOIUrl":"https://doi.org/10.55010/imcjms.16.012","url":null,"abstract":"Background and objectives: Skull base fractures have high mortality and morbidity rates and constitute a significant medical issue. The aim of the present study was to review the demographic characteristics, common locations and causes of the skull base fractures retrospectively.\u0000\u0000Methods: This retrospective study was conducted on patients who attended the Intensive Care Unit/Radiology Clinic of Adiyaman University Training and Research Hospital between 2015 and 2018 and were found to have skull base fractures. The data were accessed via PACS system of the hospital database. Age, gender, cause of the trauma, type of the skull base fracture, imaging findings and outcome of the enrolled patients were analyzed.\u0000\u0000Results: Total 138 cases who met the study criteria were enrolled in the study. The causes of the skull base fracture were as follows: fall 52.2%, traffic accident 36.2%, pounding 3.6%, firearm injury 0.7%, sharp object injury 0.7%, and other causes 6.5%. There was a statistically significant (p<0.001) difference in rate of skull base fracture caused by traffic accident between the ≤18-year group and 19-45 age group. The difference between the types of epidural hematoma was not significant in all age groups (p= 0.156); however, there was a statistically significant difference for gender (female vs. male 26.1%73.9%, p=0.025).\u0000\u0000Conclusion: Skull base fractures were more common in fall from height and traffic accidents. In order to reduce skull base fractures, it is recommended to take preventive precautions for falls from height and traffic accidents.\u0000\u0000IMC J Med Sci 2022; 16(2): 002. DOI:https://doi.org/10.55010/imcjms.16.012\u0000\u0000*Correspondence: Safiye Kafadar, Department of Radiology, Adiyaman University Education and Research Hospital, Adiyaman, Turkey. Email: safiyekafadar@gmail.com, ORCID: 0000-0003-4070-9615","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88805950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Bhuiyan, A. Mitra, Marinelle Payton, P. Tchounwou
Background and objectives: Obesity among adolescents is a significant public health concern in the United States. The prevalence of obesity has increased from 13.0% in 2011 to 15.5% in 2019. The association between breakfast skipping and obesity is still controversial, and a mediator role of depression in this association is limited. The purpose of this study was to investigate the independent association between breakfast skipping and obesity and to investigate the mediator role of depressive symptomology between breakfast skipping and obesity prevalence. Materials and methods: In this cross-sectional study, data were extracted from the CDC's Youth Risk Behavior Surveillance System (YRBSS) for 9th to 12th graders from 2011 through 2020. SAS version 9.4 was used to analyze the data using proc survey frequency and proc survey logistic regression models. The adjusted odds ratios (aORs) with 95% confidence intervals (CI) were estimated. The Sobel test also was performed to test the mediator role of self-reported depression. Results: Of the 56,320 adolescents, 13.7% did not eat breakfast, 14.1% were obese, and 15.1% had depressive symptomology. Breakfast non-eaters was associated with a 24% increased odds of obesity (aOR: 1.24; 95% CI: 1.14 to 1.36) after adjusting for race/ethnicity, gender, grade level, and behavioral risk factors. A mediator role of self-reported depression was noted using the regression model and Sobel test (z = 3.90, S.E. = 0.02, p< 0.0001) between breakfast skipping and obesity. Conclusions: Breakfast skipping was independently associated with obesity. Self-reported depression was identified as a mediator factor. Therefore, the mental health condition also needs to be addressed in the prevention of obesity among adolescents. IMC J Med Sci 2022; 16(2): 001 *Correspondence: Azad R. Bhuiyan, Department of Epidemiology and Biostatistics, School of Public Health, College of Health Sciences, Jackson State University, Jackson, MS 39213, USA. Email: azad.r.bhuiyan@jsums.edu
{"title":"Role of breakfast skipping, depression, and other risk factors for obesity: The Youth Risk Behavior Surveillance System","authors":"A. Bhuiyan, A. Mitra, Marinelle Payton, P. Tchounwou","doi":"10.55010/imcjms.16.11","DOIUrl":"https://doi.org/10.55010/imcjms.16.11","url":null,"abstract":"Background and objectives: Obesity among adolescents is a significant public health concern in the United States. The prevalence of obesity has increased from 13.0% in 2011 to 15.5% in 2019. The association between breakfast skipping and obesity is still controversial, and a mediator role of depression in this association is limited. The purpose of this study was to investigate the independent association between breakfast skipping and obesity and to investigate the mediator role of depressive symptomology between breakfast skipping and obesity prevalence.\u0000\u0000Materials and methods: In this cross-sectional study, data were extracted from the CDC's Youth Risk Behavior Surveillance System (YRBSS) for 9th to 12th graders from 2011 through 2020. SAS version 9.4 was used to analyze the data using proc survey frequency and proc survey logistic regression models. The adjusted odds ratios (aORs) with 95% confidence intervals (CI) were estimated. The Sobel test also was performed to test the mediator role of self-reported depression.\u0000\u0000Results: Of the 56,320 adolescents, 13.7% did not eat breakfast, 14.1% were obese, and 15.1% had depressive symptomology. Breakfast non-eaters was associated with a 24% increased odds of obesity (aOR: 1.24; 95% CI: 1.14 to 1.36) after adjusting for race/ethnicity, gender, grade level, and behavioral risk factors. A mediator role of self-reported depression was noted using the regression model and Sobel test (z = 3.90, S.E. = 0.02, p< 0.0001) between breakfast skipping and obesity.\u0000\u0000Conclusions: Breakfast skipping was independently associated with obesity. Self-reported depression was identified as a mediator factor. Therefore, the mental health condition also needs to be addressed in the prevention of obesity among adolescents.\u0000\u0000IMC J Med Sci 2022; 16(2): 001\u0000\u0000*Correspondence: Azad R. Bhuiyan, Department of Epidemiology and Biostatistics, School of Public Health, College of Health Sciences, Jackson State University, Jackson, MS 39213, USA. Email: azad.r.bhuiyan@jsums.edu","PeriodicalId":55816,"journal":{"name":"IMC Journal of Medical Science","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77257041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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