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Incorporating qualitative evidence in clinical practice guidelines: a Scottish perspective. 将定性证据纳入临床实践指南:苏格兰观点。
Q3 Medicine Pub Date : 2019-06-01 DOI: 10.1097/XEB.0000000000000175
Kay Cooper, Pamela Kirkpatrick, Sarah Florida-James

The current article provides an overview of an approach to incorporating a range of evidence, including qualitative research findings, which the authors piloted when developing a clinical guideline on epilepsies in children and young people. We describe methods used for incorporating literature types not usually included in Scottish Intercollegiate Guidelines Network guidelines, including critical appraisal, and establishing dependability and credibility of qualitative findings. We highlight limitations encountered and make suggestions for future work.

本文概述了一种纳入包括定性研究结果在内的一系列证据的方法,作者在制定儿童和青少年癫痫临床指南时试用了这种方法。我们描述了用于纳入通常不包括在苏格兰校际指南网络指南中的文献类型的方法,包括批判性评估,以及建立定性研究结果的可靠性和可信度。我们强调遇到的局限性,并对今后的工作提出建议。
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引用次数: 2
Development of Czech National Stroke Guidelines. 捷克国家卒中指南的制定。
Q3 Medicine Pub Date : 2019-06-01 DOI: 10.1097/XEB.0000000000000190
Radim Líčeník, Josef Bednařík, Aleš Tomek, Michal Bar, Jiří Neumann, Daniel Šaňák, Tomáš Nečas, Petra Búřilová, Jitka Klugarová, Andrea Pokorná, Miloslav Klugar

Despite a significant transformation of ischaemic stroke management, it remains one of the leading causes of death, disability, functional impairment and cognitive deficits. With the advent of intravenous thrombolysis and mechanical thrombectomy, stroke is not an untreatable disease, mostly occurring in older people, any more. The most common cause of cardioembolic strokes is atrial fibrillation or flutter and atrial fibrillation is the most prevalent arrhythmia.The aim of this short communication is to describe the methodology of the Czech stroke guidelines development.High-quality 2017 Australian Stroke Foundation stroke guideline was considered for adaptation and a new guideline was developed and disseminated.

尽管缺血性脑卒中管理发生了重大转变,但它仍然是导致死亡、残疾、功能损害和认知缺陷的主要原因之一。随着静脉溶栓和机械取栓的出现,中风不再是一种不可治愈的疾病,不再多发生在老年人身上。心栓塞性中风最常见的原因是心房颤动或扑动,心房颤动是最常见的心律失常。这篇简短通讯的目的是描述捷克卒中指南制定的方法。高质量的2017年澳大利亚卒中基金会卒中指南被考虑进行调整,并制定和传播了新的指南。
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引用次数: 3
Men's perceptions of the impact of the physical consequences of a radical prostatectomy on their quality of life: a qualitative systematic review. 男性对根治性前列腺切除术对其生活质量的生理影响的认知:一项定性的系统回顾。
Q3 Medicine Pub Date : 2019-06-01 DOI: 10.1097/XEB.0000000000000192
Deborah Edwards, Judith Carrier

A qualitative systematic review was carried out to identify men's perceptions of the impact of the physical consequences of a radicalized prostatectomy on their quality of life (QOL). The review included men of all ages and nationalities who had radicalized prostatectomy as treatment for all stages of prostate cancer. Inclusion criteria were studies that investigated the physical consequences of radicalized prostatectomy and its impact on QOL and life experience as identified by the men and the psychosocial implications of the identified physical consequences of radicalized prostatectomy as identified by the men. A search across six databases aimed to find English language studies (November 2017). Critical appraisal was conducted using the Joanna Briggs Institute critical appraisal instrument for qualitative studies. Nineteen qualitative studies were included and the findings are presented as five aggregated qualitative syntheses.Urinary incontinence and erectile dysfunction are significant side-effects of radicalized prostatectomy that have a negative impact on men's QOL for which they feel ill prepared. Men are often reluctant to discuss their emotions and therefore the need to create suitable opportunities for them to express their feelings in conjunction with appropriate evidence-based emotional support and advice is pivotal to the development of support interventions. This review highlights the importance of men being made aware of the impact the physical effects that radicalized prostatectomy can have on their QOL and that those who select radicalized prostatectomy as a treatment strategy must be provided with appropriate information and support from healthcare professionals.

进行了一项定性系统评价,以确定男性对根治性前列腺切除术对其生活质量(QOL)的生理影响的看法。该综述包括所有年龄和国籍的男性,他们接受根治性前列腺切除术作为前列腺癌各个阶段的治疗。纳入标准是研究根治性前列腺切除术的生理后果及其对男性确定的生活质量和生活体验的影响,以及男性确定的根治性前列腺切除术的生理后果的社会心理影响。旨在查找英语语言研究的六个数据库的搜索(2017年11月)。批判性评估是使用乔安娜布里格斯研究所批判性评估工具进行定性研究的。包括19项定性研究,研究结果作为5个综合定性综合提出。尿失禁和勃起功能障碍是根治性前列腺切除术的显著副作用,对男性的生活质量产生负面影响,使他们感到措手不及。男性往往不愿意讨论自己的情绪,因此需要为他们创造合适的机会来表达自己的感受,同时提供适当的基于证据的情感支持和建议,这对支持干预措施的发展至关重要。这篇综述强调了让男性意识到根治性前列腺切除术对其生活质量的影响的重要性,以及那些选择根治性前列腺切除术作为治疗策略的人必须从医疗保健专业人员那里获得适当的信息和支持。
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引用次数: 8
Occupational therapy practitioners' decision-making preferences, attitudes, awareness and barriers in relation to evidence-based practice implementation in Saudi Arabia. 职业治疗从业者的决策偏好、态度、意识和障碍与沙特阿拉伯的循证实践实施有关。
Q3 Medicine Pub Date : 2019-06-01 DOI: 10.1097/XEB.0000000000000162
Mansour A Alshehri, Rayan Falemban, Rayyan A Bukhari, Hadeel R Bakhsh

Aim: Evidence-based practice (EBP) plays a significant part in healthcare. There has been little research into the standard of care that healthcare workers provide to patients in Saudi Arabia. The purpose of this study was to investigate occupational therapy practitioners' (OTPs) decision-making preferences, attitudes and awareness in relation to EBP as well as to discover any barriers possibly limiting EBP implementation.

Methods: A cross-sectional study was conducted using an online survey. The survey was distributed to OTPs in Saudi Arabia from May to July 2018. Data were collected on demographics, decision-making preferences, attitudes and awareness as well as on the barriers obstructing implementation of EBP. The percentages and frequencies of OTPs' responses were analysed and reported. Pearson's Chi-square test was performed to explore the association between demographic variables and the attitudes and awareness of OTPs. The data were analysed using IBM SPSS Statistics 24.

Results: A total of 144 participants responded to the questionnaire, out of which 54 participants were excluded as they only completed the demographics section, and they did not answer any of the following sections. Among the completed responses (n = 90), one undergraduate participant was excluded. The final number of respondents whose data were analysed was 89 (61.8%). Out of the respondents, 58.4% were female and 73% had completed a bachelor's degree. No formal training in EBP was received by many of the respondents (53.9%). Although the attitude of 79.8% of OTPs about using research in practice was positive, a number were unfamiliar with some of the terms and with EBP implementation. The most important barrier to EBP implementation mentioned by the respondents was that their previous education had involved insufficient teaching (45%), while 42.7% mentioned inadequate resources and funding and 38.2% pointed to a lack of skills and research knowledge. The only significant association found in this study was between the awareness of OTPs and their education level.

Conclusion: Although the attitude of OTPs toward EBP implementation was positive, their awareness regarding the use of EBP was relatively low, indicating a gap in how they understand and apply EBP in Saudi Arabia. Thus, its inclusion in the curricula for graduates and undergraduates should be considered.

目的:循证实践(EBP)在医疗保健中发挥着重要作用。关于沙特阿拉伯医护人员为患者提供的护理标准的研究很少。本研究的目的是调查职业治疗从业人员(otp)的决策偏好、态度和意识与EBP有关,并发现任何可能限制EBP实施的障碍。方法:采用在线调查进行横断面研究。该调查于2018年5月至7月分发给沙特阿拉伯的otp。收集了人口统计数据、决策偏好、态度和意识以及阻碍实施EBP的障碍。分析并报告了otp应答的百分比和频率。采用Pearson卡方检验探讨人口统计学变量与otp态度和意识之间的关系。采用IBM SPSS Statistics 24对数据进行分析。结果:共有144名参与者参与了问卷调查,其中54名参与者被排除在外,因为他们只完成了人口统计部分,他们没有回答以下任何部分。在完成的回答(n = 90)中,排除了一名本科生参与者。最终被分析数据的受访者为89人(61.8%)。在受访者中,58.4%是女性,73%完成了学士学位。许多受访者(53.9%)没有接受过正式的EBP培训。尽管79.8%的otp对在实践中使用研究成果持积极态度,但许多otp不熟悉一些术语和EBP的实施。受访者提到实施EBP最重要的障碍是他们以前的教育涉及的教学不足(45%),42.7%的受访者提到资源和资金不足,38.2%的受访者指出缺乏技能和研究知识。在这项研究中发现的唯一显著关联是在OTPs的意识和他们的教育水平之间。结论:尽管沙特阿拉伯的外派人员对EBP实施的态度是积极的,但他们对EBP使用的认知度相对较低,这表明他们在如何理解和应用EBP方面存在差距。因此,应该考虑将其纳入研究生和本科生的课程。
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引用次数: 7
Czech national project 'Clinical Practice Guidelines' methodology and current results. 捷克国家项目“临床实践指南”的方法和目前的结果。
Q3 Medicine Pub Date : 2019-06-01 DOI: 10.1097/XEB.0000000000000186
Miloslav Klugar, Jitka Klugarová, Andrea Pokorná, Radim Líčeník, Dana Dolanová, Jan Mužík, Tomáš Nečas, Petra Búřilová, Martin Hunčovský, Ladislav Dušek

Currently in the Czech Republic, there does not exist such an institution as a 'National Centre for Clinical Practice Guidelines'. In 2017, there were about 123 professional medical organizations which developed about 1909 'guidelines' until 2017. However, the majority of these guidelines are 'expert opinion' or 'consensual' based 'guidance' or rather recommendations in the most cases missing a systematic approach that reflects evidence-based medicine principles and methods. The project is led by the Czech Health Research Council, the first partner is the Ministry of Health of the Czech Republic and the second partner is the Institute of Health Information and Statistics of the Czech Republic with support from policy makers, academics, clinicians and members of the Czech National Centre for Evidence-Based Healthcare and Knowledge Translations. This centre is an umbrella for three very important international collaborations which play a key role in Evidence-Based Healthcare, Evidence Synthesis, Evidence Implementation and trustworthy guidelines development. These are Cochrane Czech Republic, Masaryk University Grade Centre and the Czech Republic Centre for Evidence-Based Healthcare: The Joanna Briggs Institute Centre of Excellence.The main aim of this article is to present the Czech National Methodology of the Trustworthy Clinical Practice Guideline (CPG) development and the first results of the project 'Clinical Practice Guidelines'.A pilot phase of the project was realized during the first year of the project from January to December 2018. As the first step, there were established managing authorities including a Guarantee Committee and an Appraisal (Methodological) Committee. The Members of the Appraisal Committee developed a pilot version of the National Methodology of CPG development based on the best available approaches to Trustworthy CPGs development followed by testing on the first five pilot CPGs.

目前在捷克共和国,不存在“国家临床实践指南中心”这样的机构。2017年,约有123家专业医疗机构制定了约1909份“指南”。然而,这些指南中的大多数是基于“专家意见”或“共识”的“指导”,或者更确切地说,是在大多数情况下缺乏反映循证医学原则和方法的系统方法的建议。该项目由捷克卫生研究委员会领导,第一个合作伙伴是捷克共和国卫生部,第二个合作伙伴是捷克共和国卫生信息和统计研究所,得到了决策者、学者、临床医生和捷克国家循证保健和知识翻译中心成员的支持。该中心是三个非常重要的国际合作的保护伞,在循证医疗保健、证据合成、证据实施和可信指南制定方面发挥关键作用。它们是捷克共和国科克伦、马萨里克大学年级中心和捷克共和国循证医疗保健中心:乔安娜布里格斯研究所卓越中心。本文的主要目的是介绍捷克国家可信赖临床实践指南(CPG)的发展方法和“临床实践指南”项目的第一个结果。在项目的第一年(2018年1月至12月)实现了项目的试点阶段。作为第一步,设立了管理机构,包括一个保证委员会和一个评估(方法)委员会。评估委员会成员根据可信赖的可持续发展目标制定的最佳方法,制定了国家可持续发展目标制定方法的试点版本,随后对前五个试点可持续发展目标进行了测试。
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引用次数: 4
Evaluation of an evidence-based model of safeguarding clinical supervision within one healthcare organization in the United Kingdom. 在英国的一个医疗保健组织中,评估一个以证据为基础的临床监督保障模式。
Q3 Medicine Pub Date : 2019-06-01 DOI: 10.1097/XEB.0000000000000180
Julie McGarry, Aimee Aubeeluck, Deborah De Oliveira

Aim: Clinical supervision has been recognized as a valuable mechanism through which healthcare professionals may evaluate, reflect upon and develop their clinical practice within the context of safeguarding. However, while there is a general consensus with regard to the value of clinical supervision there are multiple approaches to utilization in practice. This brief communication provides an overview of an evaluation of one model of safeguarding clinical supervision which was explicitly developed to support healthcare professionals in their everyday practice.

Methods: The current study used a survey approach, which involved the development and administration of an online anonymous survey with clinical supervisors and supervisees working within the one service of the Trust.

Results: The survey results showed that individuals were overall confident, knowledgeable and satisfied with their safeguarding supervisions. However, individuals at a lower band were significantly less positive about supervision, particularly in relation to how much they felt enabled to explore their safeguard concerns, how much they felt equipped to provide/receive safeguarding supervision and about how much they understood clearly the difference between managerial supervision/clinical and safeguarding supervision.

Conclusion: A number of key recommendations arising from the findings of the evaluation are presented in this article and are considered in terms of the question 'what constituents form the core components of a successful Safeguarding Supervision Framework relationship?'

目的:临床监督已被认为是一种有价值的机制,通过这种机制,医疗保健专业人员可以在保护的背景下评估、反思和发展他们的临床实践。然而,尽管对临床监督的价值有一个普遍的共识,但在实践中有多种使用方法。这篇简短的交流概述了一种保护临床监督的模型的评估,该模型是明确开发的,用于支持医疗保健专业人员的日常实践。方法:目前的研究采用了一种调查方法,其中涉及开发和管理一个在线匿名调查与临床监督者和监督者工作在一个服务的信托。结果:调查结果显示,个人总体上有信心,有知识,对自己的保障监督感到满意。然而,处于较低水平的个体对监督的积极程度明显较低,特别是在他们觉得能够探索他们的保障问题的程度、他们觉得有能力提供/接受保障监督的程度以及他们对管理监督/临床监督和保障监督之间的区别的理解程度方面。结论:本文提出了从评估结果中产生的一些关键建议,并根据“成功的保障监管框架关系的核心组成部分是什么”这一问题进行了考虑?
{"title":"Evaluation of an evidence-based model of safeguarding clinical supervision within one healthcare organization in the United Kingdom.","authors":"Julie McGarry,&nbsp;Aimee Aubeeluck,&nbsp;Deborah De Oliveira","doi":"10.1097/XEB.0000000000000180","DOIUrl":"https://doi.org/10.1097/XEB.0000000000000180","url":null,"abstract":"<p><strong>Aim: </strong>Clinical supervision has been recognized as a valuable mechanism through which healthcare professionals may evaluate, reflect upon and develop their clinical practice within the context of safeguarding. However, while there is a general consensus with regard to the value of clinical supervision there are multiple approaches to utilization in practice. This brief communication provides an overview of an evaluation of one model of safeguarding clinical supervision which was explicitly developed to support healthcare professionals in their everyday practice.</p><p><strong>Methods: </strong>The current study used a survey approach, which involved the development and administration of an online anonymous survey with clinical supervisors and supervisees working within the one service of the Trust.</p><p><strong>Results: </strong>The survey results showed that individuals were overall confident, knowledgeable and satisfied with their safeguarding supervisions. However, individuals at a lower band were significantly less positive about supervision, particularly in relation to how much they felt enabled to explore their safeguard concerns, how much they felt equipped to provide/receive safeguarding supervision and about how much they understood clearly the difference between managerial supervision/clinical and safeguarding supervision.</p><p><strong>Conclusion: </strong>A number of key recommendations arising from the findings of the evaluation are presented in this article and are considered in terms of the question 'what constituents form the core components of a successful Safeguarding Supervision Framework relationship?'</p>","PeriodicalId":55996,"journal":{"name":"International Journal of Evidence-Based Healthcare","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/XEB.0000000000000180","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37407154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tracheostomy decannulation methods and procedures for assessing readiness for decannulation in adults: a systematic scoping review. 成人气管切开术脱管的方法和程序评估脱管准备:系统的范围审查。
Q3 Medicine Pub Date : 2019-06-01 DOI: 10.1097/XEB.0000000000000166
John Kutsukutsa, Desmond Kuupiel, Anna Monori-Kiss, Paula Del Rey-Puech, Tivani P Mashamba-Thompson

Despite the undisputable benefits of tracheostomy, it has been reported to have links with impaired communication, reduced quality of life and a risk of health complications such as bleeding, tracheal stenosis and in some cases resulting in mortality. There is a paucity of literature on tracheostomy decannulation methods and procedures, leaving the decision to expert opinion and institutional guidelines. This study aimed to map evidence on methods and procedures of tracheostomy decannulation in adults and assessment of readiness for decannulation, to reveal knowledge gaps and inform further research. We conducted a systematic search of peer reviewed and grey literature on PubMed/MEDLINE, Google Scholar, Union Catalogue of Theses and Dissertations via SABINET Online, World Cat Dissertations and Theses via OCLC, WHO library and governmental websites from 1985 to present. Following title screening, abstract and full article screening was performed by two independent reviewers guided by the eligibility criteria. Data from included studies were extracted, collated, summarized and synthesized into the following themes: assessment, removal, monitoring and definition of failure of decannulation. Quality of the included studies was assessed using the Mixed Methods Appraisal Tool version 2011. Twenty-five out of 51 screened articles were eligible for data extraction. There was wide variation in the assessment methods employed across and within similar patient groups. The common themes that emerged in the assessment for readiness for decannulation are informed consent, clinical stability, airway patency, physiological decannulation, swallowing assessment, level of consciousness, effectiveness of cough and clearance of secretions. In conclusion, the current body of evidence is inadequate and requires further research, particularly validation of different parameters used. A protocol approach to decannulation may be inappropriate but rather an algorithmic approach using validated parameters.

尽管气管切开术有无可争辩的好处,但据报道,它与沟通障碍、生活质量下降和出血、气管狭窄等健康并发症的风险有关,在某些情况下还会导致死亡。关于气管切开术的方法和程序的文献很少,留给专家意见和机构指南来决定。本研究旨在绘制成人气管切开术脱管的方法和程序的证据,并评估脱管准备情况,以揭示知识差距并为进一步的研究提供信息。我们系统地检索了1985年至今的PubMed/MEDLINE、Google Scholar、SABINET Online的联合论文目录、OCLC、WHO图书馆和政府网站上的世界猫论文和论文的同行评议文献和灰色文献。在标题筛选之后,由两位独立的审稿人根据资格标准进行摘要和全文筛选。从纳入的研究中提取、整理、总结并综合以下主题:评估、移除、监测和定义脱管失败。纳入研究的质量采用2011版混合方法评估工具进行评估。51篇筛选文章中有25篇符合数据提取条件。在相似的患者组之间和内部采用的评估方法存在很大差异。在准备撤管评估中出现的共同主题是知情同意,临床稳定性,气道通畅,生理撤管,吞咽评估,意识水平,咳嗽有效性和分泌物清除。总之,目前的证据是不充分的,需要进一步的研究,特别是对使用的不同参数的验证。协议方法可能不合适,而是使用经过验证的参数的算法方法。
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引用次数: 18
Moving towards a standards-based methodological quality assessment scheme for clinical research. 向基于标准的临床研究方法学质量评估方案迈进。
Q3 Medicine Pub Date : 2019-06-01 DOI: 10.1097/XEB.0000000000000170
Jennifer C Stone, Suhail A R Doi
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引用次数: 2
Developing guideline-based quality indicators: assessing gaps in pain management practice. 制定基于指南的质量指标:评估疼痛管理实践中的差距。
Q3 Medicine Pub Date : 2019-06-01 DOI: 10.1097/XEB.0000000000000160
Valerie J Fiset, Barbara L Davies, Ian D Graham, Wendy Gifford, Kirsten Woodend

Aim: In this article, the authors discuss a multiphase approach for developing quality indicators based on pain practice guidelines, and the challenges associated with the process. The presentation is based on previously published reporting standards for guideline-based quality indicators.

Methods: The following steps of the indicator development process were undertaken: topic selection; guideline selection; extraction of recommendations; quality indicator selection and practice test.

Results: Eleven practice guidelines were reviewed for quality, and three high-quality guidelines were compared for pertinent recommendations. From these three guidelines, 12 recommendations were extracted and judged appropriate to examine the practice gap for nursing students and clinicians on an oncology and palliative care unit. Quality indicators were then identified by a consensus process, resulting in 24 discrete indicators that were included in the practice test.

Conclusion: Quality indicators can be used to examine gaps in pain management practice, and to evaluate change after guideline implementation. However, their development can be challenging, and guideline developers could facilitate uptake of guidelines by including clear, relevant quality indicators as part of guideline creation and presentation.

目的:在这篇文章中,作者讨论了基于疼痛实践指南开发质量指标的多阶段方法,以及与该过程相关的挑战。报告是根据以前公布的基于准则的质量指标报告标准编写的。方法:在指标制定过程中采取以下步骤:选题;指导选择;建议提取;质量指标选择与实践检验。结果:对11份实践指南进行了质量评估,并对3份高质量指南进行了相关建议的比较。从这三个指南中,提取了12条建议,并判断为适当的,以检查肿瘤和姑息治疗单位的护理学生和临床医生的实践差距。质量指标然后由一个一致的过程确定,产生24个离散的指标,包括在实践测试中。结论:质量指标可用于检查疼痛管理实践的差距,并评价指南实施后的变化。然而,它们的发展可能具有挑战性,指南的开发者可以通过将清晰、相关的质量指标作为指南创建和呈现的一部分来促进指南的吸收。
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引用次数: 7
Analysis of heterogeneity in a systematic review using meta-regression technique. 运用元回归技术分析系统综述中的异质性。
Q3 Medicine Pub Date : 2019-06-01 DOI: 10.1097/XEB.0000000000000163
Kenneth Lo, Matthew Stephenson, Craig Lockwood

Aim: Heterogeneity is an important consideration in systematic reviews, as high heterogeneity may imply that it is not suitable to perform meta-analysis. The degree of variation could be caused by clinical or methodological differences among the studies, or it could be due to the randomness of chance. Methods of assessing heterogeneity are calculating a statistical test for heterogeneity (the I value), visual evaluations of forest plots, conducting subgroup analysis or meta-regression. We conducted meta-regression on data of our previous systematic review on the effectiveness of robotic rehabilitation, and in this article, we present the findings and discuss its implications.

Method: In our meta-regression plots, plotted on the x-axis was the trial covariate (duration of intervention group therapy), and plotted on the y-axis was the effect size measure (standardized mean differences), with positive effect sizes favouring robotic intervention. Analysis using random effects was applied, and each study symbol was sized in proportion to its precision (inverse-variance weighting).

Results: Differences were observed in the meta-regression plots between the subgroups of therapy ratio = 0 and therapy ratio more than 0 for upper limb movement, lower limb walking and activities of daily living. For upper limb movement, positive linear relationships were found for both subgroups. However, in terms of the strength of the relationship, a stronger relationship was found for therapy ratio = 0. For lower limb walking, opposing linear relationships were found in both subgroups: therapy ratio = 0 had a negative linear relationship, whereas therapy ratio more than 0 had a positive linear relationship. For activities of daily living, positive linear relationships were found for both subgroups, but a stronger linear relationship was found for therapy ratio = 0.

Conclusion: From the meta-regression analysis, we found that differing levels of linear relationships and the varying spread of effect sizes across positive and negative ranges were the likely sources of heterogeneity. This was especially so in the meta-regression of lower limb walking, which showed opposing directions of linear relationships. The wider spread of effect sizes for therapy ratio = 0 could indicate that some robotic devices were more effective than others. In addition, for therapy ratio more than 0, the effect sizes were mainly found in the positive region, which implied that adding conventional training to robotic training was generally positive for robotic devices.

目的:异质性是系统评价的一个重要考虑因素,因为高异质性可能意味着不适合进行荟萃分析。差异的程度可能是由临床或研究方法的差异引起的,也可能是由于机会的随机性。评估异质性的方法是计算异质性的统计检验(I值)、森林样地的目视评价、进行亚组分析或元回归。我们对之前关于机器人康复有效性的系统综述数据进行了meta回归,在本文中,我们提出了研究结果并讨论了其含义。方法:在我们的meta回归图中,x轴为试验协变量(干预组治疗持续时间),y轴为效应量测量(标准化平均差异),正效应量倾向于机器人干预。采用随机效应进行分析,每个研究符号的大小与其精度成比例(逆方差加权)。结果:在上肢运动、下肢行走和日常生活活动方面,治疗比率= 0和治疗比率大于0的亚组间的meta回归图有差异。对于上肢运动,两个亚组均发现正线性关系。然而,就关系的强度而言,治疗比率= 0时,关系更强。对于下肢行走,两个亚组均存在相反的线性关系:治疗比率= 0为负线性关系,而治疗比率大于0为正线性关系。对于日常生活活动,两个亚组都发现了正线性关系,但在治疗比率= 0时发现了更强的线性关系。结论:从meta回归分析中,我们发现不同程度的线性关系和效应大小在正、负范围内的不同分布可能是异质性的来源。这在下肢行走的元回归中尤其如此,显示出相反方向的线性关系。治疗比率= 0时效应大小的更大范围可能表明一些机器人设备比其他设备更有效。此外,当治疗比大于0时,效应量主要出现在正区域,这意味着在机器人训练中加入常规训练对机器人装置总体上是正的。
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引用次数: 8
期刊
International Journal of Evidence-Based Healthcare
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