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Three-dimensional evaluation of maxillary tooth movement in extraction patients with three different miniscrew anchorage systems: a randomized controlled trial. 三种不同微支抗系统拔牙患者上颌牙移动的三维评价:一项随机对照试验。
IF 4.8 2区 医学 Q1 Dentistry Pub Date : 2022-12-19 DOI: 10.1186/s40510-022-00441-4
Liwen Zhang, Runzhi Guo, Baohua Xu, Yue Wang, Weiran Li

Objective: To compare the three-dimensional (3-D) movement of maxillary teeth in response to three common miniscrew anchorage systems in extraction patients with maxillary dentoalveolar protrusion.

Materials and methods: The study employed a randomized controlled single-blinded design with three arms. Thirty extraction patients who required maximum anchorage to retract maxillary anterior teeth were included and randomly allocated into three treatment groups: space closure with direct miniscrew anchorage and low crimpable hooks (DL group), indirect miniscrew anchorage and low crimpable hooks (IL group), and direct miniscrew anchorage and high crimpable hooks (DH group). Cone beam computed tomography (CBCT) images of all included patients were obtained immediately before (T0) and after (T1) space closure. The outcomes were 3-D positional changes of maxillary central incisor, lateral incisor, canine, second premolar, and first molar. The repeated measures analysis of variance with post hoc LSD test was used to evaluate differences among groups.

Results: A significant intrusion (- 1.34 mm; 95% CI, - 1.60 mm, 1.08 mm) and buccal (- 6.92°; 95% CI, - 8.67°, - 5.13°) and distal (4.90°; 95% CI, 3.75°, 6.04°) inclination of the maxillary first molars were observed in the DL group, compared to the other two groups. The mesial movement (- 0.40 mm; 95% CI, - 0.83 mm, - 0.03 mm) of the maxillary first molars was found in the IL group, while the DL (0.44 mm; 95% CI, 0.15 mm, 0.73 mm) and IL (0.62 mm; 95% CI, 0.28 mm, 0.96 mm) groups exhibited distal movement. In the DH group, the lingual inclination changes of maxillary central incisor (5.04°; 95% CI, 2.82°, 7.26°) were significantly lower, which is indicative of good lingual root torque control of the maxillary anterior teeth.

Conclusion: Three miniscrew anchorage systems produced significantly different 3-D maxillary tooth movement. The maxillary first molars were significantly buccally and distally inclined and intruded in patients using direct miniscrew anchorages with low crimpable hooks. Direct miniscrew anchorages with high crimpable hooks could help to achieve better lingual root torque control of the maxillary incisors. Trial registration The trial was registered at www.chictr.org.cn (ChiCTR1900026960). Registered 27 October 2019.

目的:比较上颌牙槽突拔牙患者在三种常用的微型支抗系统下上颌牙的三维运动情况。材料与方法:本研究采用三组随机对照单盲设计。选取30例需要最大支抗的拔牙患者,随机分为间隙闭合直接微支抗低卷曲钩组(DL组)、间接微支抗低卷曲钩组(IL组)、直接微支抗高卷曲钩组(DH组)。所有患者的锥形束ct (Cone beam computed tomography, CBCT)图像均在(T0)和(T1)空间闭合前立即获得。结果显示上颌中切牙、侧切牙、犬齿、第二前磨牙和第一磨牙的三维位置变化。采用重复测量方差分析和事后LSD检验来评价组间差异。结果:明显的侵入(- 1.34 mm;95% CI, - 1.60 mm, 1.08 mm)和颊部(- 6.92°;95% CI, - 8.67°,- 5.13°)和远端(4.90°;与其他两组相比,DL组上颌第一磨牙的倾斜度为95% CI(3.75°,6.04°)。中距运动(- 0.40 mm;IL组上颌第一磨牙的95% CI为- 0.83 mm, - 0.03 mm; DL组上颌第一磨牙的95% CI为0.44 mm;95% CI, 0.15 mm, 0.73 mm)和IL (0.62 mm;95% CI, 0.28 mm, 0.96 mm)组表现为远端运动。DH组上颌中切牙舌倾角变化(5.04°;95% CI(2.82°,7.26°)明显降低,说明上颌前牙舌根力矩控制良好。结论:三种微型支抗系统对上颌牙的三维运动有显著的影响。上颌第一磨牙使用低卷曲钩直接微支抗时,上颌第一磨牙明显向颊部和远端倾斜和侵入。采用高卷曲钩直接微型支抗可以更好地控制上颌切牙的舌根扭矩。试验注册:www.chictr.org.cn (ChiCTR1900026960)。注册于2019年10月27日。
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引用次数: 1
Εffect of cleansers on the composition and mechanical properties of orthodontic aligners in vitro. Εffect清洁剂对体外正畸矫正器的组成和机械性能的影响。
IF 4.8 2区 医学 Q1 Dentistry Pub Date : 2022-12-15 DOI: 10.1186/s40510-022-00449-w
Anna Iliadi, Vera Enzler, Georgios Polychronis, Timo Peltomaki, Spiros Zinelis, Theodore Eliades

Background: The aim of the study was to investigate the effect of three aligner cleaners on the composition and mechanical properties of two types of orthodontic aligners.

Materials and methods: The cleaners tested were two alkaline peroxide solutions (Retainer Brite-RB; Retainer Cleaner-RC) and one peroxide-free (Steraligner-ST) and the aligners Clear Aligner (C, polyester) and Invisalign (I, polyester-urethane). The aligners were immersed in the cleaner solutions as instructed every day (15 min for RB, RC; 5 min for ST) for a two-week period. The acidity of the solutions was tested with a pH meter. The changes in the chemical composition of the aligners were studied by attenuated total-reflection Fourier transform infrared spectrometry (ATR-FTIR), while Instrumented Indentation Testing (IIT) was used for assessment of changes in Martens Hardness (HM), modulus (EIT), elastic index (nIT) and relaxation (RIT).

Results: RB and RC were weakly acidic (pH = 6.3), whereas ST was mildly acidic (pH = 4.8). The ATR-FTIR analysis demonstrated evidence of acidic hydrolysis of C in ST and I in RB. The IIT-derived properties of I were not affected by the cleaners. However, for C a significant change was found in HM (all cleaners), nIT (all cleaners) and RIT (RB, ST). Although the chemical changes support a hydrolytic material deterioration, the results of mechanical properties may interfere with the material residual stresses during fabrication.

Conclusions: Caution should be exerted in the selection of aligner cleaners. The mild acidic cleanser was more aggressive to the polyester, whereas an alkaline peroxide to the polyester-urethane aligner.

背景:本研究的目的是探讨三种矫正器清洁剂对两种正畸矫正器组成和力学性能的影响。材料和方法:测试的清洁剂为两种碱性过氧化溶液(Retainer Brite-RB;固定器清洁剂- rc)和一种无过氧化物(Steraligner-ST)和矫正器Clear Aligner (C,聚酯)和Invisalign (I,聚酯-聚氨酯)。每天按照指示将矫正器浸入清洗液中(RB, RC为15分钟;5分钟(ST),为期两周。用pH计测试了溶液的酸度。采用衰减全反射傅立叶变换红外光谱法(ATR-FTIR)研究了对准剂化学成分的变化,采用仪器压痕测试(IIT)评估了对准剂的马氏硬度(HM)、模量(EIT)、弹性指数(nIT)和弛豫(RIT)的变化。结果:RB和RC呈弱酸性(pH = 6.3), ST呈弱酸性(pH = 4.8)。ATR-FTIR分析证实了ST中C和RB中I的酸性水解。iit衍生的I的性质不受清洁剂的影响。然而,对于C,在HM(所有清洁剂)、nIT(所有清洁剂)和RIT (RB、ST)中发现了显著变化。虽然化学变化支持水解材料变质,但机械性能的结果可能会干扰材料在制造过程中的残余应力。结论:在选择牙齿矫正器清洁剂时应谨慎。温和的酸性清洁剂对聚酯更具侵略性,而碱性过氧化氢对聚酯-聚氨酯校准剂更具侵略性。
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引用次数: 2
Comparison of rapid versus slow maxillary expansion on patient-reported outcome measures in growing patients: a systematic review and meta-analysis. 快速与缓慢上颌扩张对生长患者报告结果测量的比较:一项系统回顾和荟萃分析。
IF 4.8 2区 医学 Q1 Dentistry Pub Date : 2022-12-12 DOI: 10.1186/s40510-022-00440-5
Valentina Rutili, Michele Nieri, Debora Franceschi, Felicita Pierleoni, Veronica Giuntini, Lorenzo Franchi

Background: No systematic review and meta-analysis are present in the literature comparing patient-reported outcome measures (PROMs) in rapid maxillary expansion (RME) versus slow maxillary expansion (SME) in growing patients.

Objective: The objective of this systematic review was to compare PROMs in RME versus SME in growing patients.

Materials and methods: Electronic search in PubMed (MEDLINE), Cochrane Library, Scopus, Embase, Web of Science, and OpenGrey was conducted. Only RCTs were included. Inclusion criteria were: growing patients in the mixed dentition or early permanent dentition, mild-to-moderate maxillary transverse deficiency, dental crowding, treatment with fixed expanders for rapid and slow maxillary expansion. Risk of bias was assessed using RoB 2. GRADE statement was performed. The mean of the differences (MD) and the risk ratio (RR) were used for the aggregation of data. A random effect model was applied.

Results: Two articles with a total of 157 patients were finally included in the systematic review and meta-analysis. One article was at low risk of bias, while one was at risk of bias with some concerns. Pain presence was less, though not statistically significant, in SME patients (RR = 2.02, 95%CI from 0.55 to 7.49, P = 0.29, I2 = 95%, 2 studies, GRADE very low). Pain intensity was significantly lower in SME appliance in the first week of treatment (pooled MD = 0.86 favoring SME, 95%CI from 0.47 to 1.26, P < 0.0001, I2 = 6%, 2 studies, GRADE moderate). There were no significant differences between the two groups in difficulty in speaking, difficulty in swallowing, hypersalivation, difficulty in hygiene, and patient and parent satisfaction.

Conclusions: Pain intensity was significantly lower in SME compared to RME during the first week of treatment. For the following weeks, there were no differences in pain between the two protocols.

背景:文献中没有系统回顾和荟萃分析比较患者报告的结果测量(PROMs)在快速上颌扩张(RME)和缓慢上颌扩张(SME)患者中。目的:本系统综述的目的是比较生长中的RME和SME患者的PROMs。材料和方法:在PubMed (MEDLINE)、Cochrane Library、Scopus、Embase、Web of Science和OpenGrey中进行电子检索。仅纳入随机对照试验。纳入标准为:生长在混合牙列或早期恒牙列的患者,上颌轻度至中度横向缺陷,牙齿拥挤,使用固定扩张器进行上颌快速和缓慢扩张。偏倚风险采用RoB 2进行评估。执行GRADE语句。采用差异均值(MD)和风险比(RR)进行数据汇总。采用随机效应模型。结果:两篇文章共157例患者最终被纳入系统评价和荟萃分析。一篇文章存在低偏倚风险,另一篇文章存在存在一些问题的偏倚风险。SME患者的疼痛发生率较低,但无统计学意义(RR = 2.02, 95% ci为0.55 ~ 7.49,P = 0.29, I2 = 95%, 2项研究,GRADE非常低)。在治疗的第一周,SME矫治器的疼痛强度显著降低(合并MD = 0.86, 95%CI从0.47到1.26,P 2 = 6%, 2项研究,GRADE中等)。两组患儿在说话困难、吞咽困难、唾液过多、卫生困难、患者和家长满意度方面均无显著差异。结论:在治疗的第一周,SME的疼痛强度明显低于RME。在接下来的几周内,两种方案之间的疼痛没有差异。
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引用次数: 3
External root resorption (ERR) and rapid maxillary expansion (RME) at post-retention stage: a comparison between tooth-borne and bone-borne RME. 牙源性和骨源性牙源性外根吸收与上颌快速扩张的比较
IF 4.8 2区 医学 Q1 Dentistry Pub Date : 2022-12-05 DOI: 10.1186/s40510-022-00439-y
Rosalia Leonardi, Vincenzo Ronsivalle, Ersilia Barbato, Manuel Lagravère, Carlos Flores-Mir, Antonino Lo Giudice

Background: The study aimed to compare external root resorption (ERR) three-dimensionally in subjects treated with tooth-borne (TB) versus bone-borne (BB) rapid maxillary expansion (RME). Forty subjects who received tooth-borne RME (TB group, average age 13.3 years ± 1.10 years) or bone-borne RME (BB group, average age 14.7 ± 1.15 years) were assessed using CBCT imaging before treatment (T0) and after a 6-month retention period (T1). 3D reconstructions of the radicular anatomy of maxillary first molars (M1), first and second premolars (P1 and P2) were generated to calculate volumetric (mean and percentage values) and shape changes (deviation analysis of the radicular models) obtained at each time point. 2D assessment of radicular length changes was also performed for each tooth. Data were statistically analyzed to perform intra-group (different teeth) and inter-group comparisons.

Results: In both groups, all the investigated teeth showed a significant reduction in radicular volume and length (p < 0.05), with the first molars being the teeth most affected by the resorption process (volume and palatal root length). When volumetric radicular changes were calculated as a percentage of the pre-treatment volumes, no differences were found among the investigated teeth (p > 0.05). Based on the deviation analysis from radicular models superimposition, the areas most affected by shape change were the apex and bucco-medial root surface. Overall, the amount of ERR was significantly greater in the TB group (mm3: M1 = 17.03, P1 = 6.42, P2 = 5.26) compared to the BB group (mm3: M1 = 3.11, P1 = 1.04, P2 = 1.24).

Conclusions: Despite the statistical significance, the difference in the amount of ERR of the posterior maxillary dentition between TB-RME and BB-RME remains clinically questionable.

背景:本研究旨在比较牙源性(TB)和骨源性(BB)上颌快速扩张(RME)治疗对象的三维外根吸收(ERR)。对40例接受牙源性RME (TB组,平均年龄13.3±1.10岁)或骨源性RME (BB组,平均年龄14.7±1.15岁)治疗前(T0)和留置期6个月(T1)后的CBCT成像进行评估。生成上颌第一磨牙(M1)、第一和第二前磨牙(P1和P2)根状解剖的三维重建,计算每个时间点获得的体积(平均值和百分比值)和形状变化(根状模型的偏差分析)。对每颗牙齿进行牙根长度变化的二维评估。对数据进行统计分析,进行组内(不同牙)和组间比较。结果:两组牙根体积和根长均明显减小(p < 0.05)。根据根模型叠加的偏差分析,受形状变化影响最大的区域是根尖面和根中面。总体而言,与BB组(mm3: M1 = 3.11, P1 = 1.04, P2 = 1.24)相比,TB组(mm3: M1 = 17.03, P1 = 6.42, P2 = 5.26) ERR的数量显著增加。结论:TB-RME与BB-RME在上颌后牙列ERR数量上的差异虽有统计学意义,但在临床上仍存在疑问。
{"title":"External root resorption (ERR) and rapid maxillary expansion (RME) at post-retention stage: a comparison between tooth-borne and bone-borne RME.","authors":"Rosalia Leonardi,&nbsp;Vincenzo Ronsivalle,&nbsp;Ersilia Barbato,&nbsp;Manuel Lagravère,&nbsp;Carlos Flores-Mir,&nbsp;Antonino Lo Giudice","doi":"10.1186/s40510-022-00439-y","DOIUrl":"https://doi.org/10.1186/s40510-022-00439-y","url":null,"abstract":"<p><strong>Background: </strong>The study aimed to compare external root resorption (ERR) three-dimensionally in subjects treated with tooth-borne (TB) versus bone-borne (BB) rapid maxillary expansion (RME). Forty subjects who received tooth-borne RME (TB group, average age 13.3 years ± 1.10 years) or bone-borne RME (BB group, average age 14.7 ± 1.15 years) were assessed using CBCT imaging before treatment (T0) and after a 6-month retention period (T1). 3D reconstructions of the radicular anatomy of maxillary first molars (M1), first and second premolars (P1 and P2) were generated to calculate volumetric (mean and percentage values) and shape changes (deviation analysis of the radicular models) obtained at each time point. 2D assessment of radicular length changes was also performed for each tooth. Data were statistically analyzed to perform intra-group (different teeth) and inter-group comparisons.</p><p><strong>Results: </strong>In both groups, all the investigated teeth showed a significant reduction in radicular volume and length (p < 0.05), with the first molars being the teeth most affected by the resorption process (volume and palatal root length). When volumetric radicular changes were calculated as a percentage of the pre-treatment volumes, no differences were found among the investigated teeth (p > 0.05). Based on the deviation analysis from radicular models superimposition, the areas most affected by shape change were the apex and bucco-medial root surface. Overall, the amount of ERR was significantly greater in the TB group (mm<sup>3</sup>: M1 = 17.03, P1 = 6.42, P2 = 5.26) compared to the BB group (mm<sup>3</sup>: M1 = 3.11, P1 = 1.04, P2 = 1.24).</p><p><strong>Conclusions: </strong>Despite the statistical significance, the difference in the amount of ERR of the posterior maxillary dentition between TB-RME and BB-RME remains clinically questionable.</p>","PeriodicalId":56071,"journal":{"name":"Progress in Orthodontics","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2022-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40548140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Force profile assessment of direct-printed aligners versus thermoformed aligners and the effects of non-engaged surface patterns. 直接打印对准器与热成型对准器的力剖面评估以及非接合表面图案的影响。
IF 4.8 2区 医学 Q1 Dentistry Pub Date : 2022-11-29 DOI: 10.1186/s40510-022-00443-2
Evan Hertan, Julie McCray, Brent Bankhead, Ki Beom Kim

Background: The purpose of the study was to measure the forces delivered by direct-printed aligners (DPA) in the vertical dimension and compare the force profile with traditional thermoformed aligners (TFA) and to investigate the impact of non-engaged surface patterns to the properties of DPA and TFA.

Methods: A force-measuring appliance was fabricated capable of displacing the aligner in 0.10 mm increments and measuring the resultant force. Polyethylene terephthalate glycol (ATMOS 0.030″ American Orthodontics) and TC-85DAC resin (Graphy Inc) were used to create TFA and DPA, respectively. Aligners were temperature-controlled prior to and during testing to simulate the oral environment. The resultant forces from displacements ranging from 0.10 to 0.30 mm were measured.

Results: At intraoral temperatures, DPA demonstrated significantly less force than TFA. TFA demonstrated a substantial statistically significant increase in force with each 0.10 mm increase in vertical displacement. DPA demonstrated a much more consistent force profile across the range of displacements. The effects of surface patterns in both DPA and TFA were generally a decrease in force. Statistical significance of surface patterns was detected for TFA at displacements of 0.30 mm and greater and significant for DPA only at a displacement of 0.10 mm. Surface patterns in both DPA and the TFA did not show any statistical difference when assessing force proprieties.

Conclusions: Forces delivered by aligners in the vertical dimension by DPA are more consistent and of lower magnitude than those of TFA aligners. Surface patterns were not capable of altering the force properties of both DPA and TFA.

背景:本研究的目的是测量直接打印矫直器(DPA)在垂直尺寸上传递的力,并将其与传统热成型矫直器(TFA)的力分布进行比较,并研究非接合表面图案对DPA和TFA性能的影响。方法:制作了一种力测量器,能够以0.10 mm的增量位移对准器并测量合力。采用聚对苯二甲酸乙二醇酯(ATMOS 0.030″American Orthodontics)和TC-85DAC树脂(Graphy Inc)分别制备TFA和DPA。矫正器在测试前和测试期间都进行了温度控制,以模拟口腔环境。测量了位移范围为0.10至0.30 mm的合力。结果:在口内温度下,DPA的受力明显小于TFA。TFA显示,垂直位移每增加0.10 mm,力就会显著增加。DPA在整个位移范围内显示出更加一致的力分布。在DPA和TFA中,表面图案的影响通常是力的降低。在位移为0.30 mm及更大的TFA中检测到表面图案的统计学意义,而DPA仅在位移为0.10 mm时才具有统计学意义。在评估力特性时,DPA和TFA的表面模式没有显示出任何统计学差异。结论:与TFA矫正器相比,DPA矫正器在垂直维度上施加的力更一致,且强度更小。表面图案不能改变DPA和TFA的力性能。
{"title":"Force profile assessment of direct-printed aligners versus thermoformed aligners and the effects of non-engaged surface patterns.","authors":"Evan Hertan,&nbsp;Julie McCray,&nbsp;Brent Bankhead,&nbsp;Ki Beom Kim","doi":"10.1186/s40510-022-00443-2","DOIUrl":"https://doi.org/10.1186/s40510-022-00443-2","url":null,"abstract":"<p><strong>Background: </strong>The purpose of the study was to measure the forces delivered by direct-printed aligners (DPA) in the vertical dimension and compare the force profile with traditional thermoformed aligners (TFA) and to investigate the impact of non-engaged surface patterns to the properties of DPA and TFA.</p><p><strong>Methods: </strong>A force-measuring appliance was fabricated capable of displacing the aligner in 0.10 mm increments and measuring the resultant force. Polyethylene terephthalate glycol (ATMOS 0.030″ American Orthodontics) and TC-85DAC resin (Graphy Inc) were used to create TFA and DPA, respectively. Aligners were temperature-controlled prior to and during testing to simulate the oral environment. The resultant forces from displacements ranging from 0.10 to 0.30 mm were measured.</p><p><strong>Results: </strong>At intraoral temperatures, DPA demonstrated significantly less force than TFA. TFA demonstrated a substantial statistically significant increase in force with each 0.10 mm increase in vertical displacement. DPA demonstrated a much more consistent force profile across the range of displacements. The effects of surface patterns in both DPA and TFA were generally a decrease in force. Statistical significance of surface patterns was detected for TFA at displacements of 0.30 mm and greater and significant for DPA only at a displacement of 0.10 mm. Surface patterns in both DPA and the TFA did not show any statistical difference when assessing force proprieties.</p><p><strong>Conclusions: </strong>Forces delivered by aligners in the vertical dimension by DPA are more consistent and of lower magnitude than those of TFA aligners. Surface patterns were not capable of altering the force properties of both DPA and TFA.</p>","PeriodicalId":56071,"journal":{"name":"Progress in Orthodontics","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2022-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705625/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40502184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Predictability of crowding resolution in clear aligner treatment. 在明确对准治疗拥挤分辨率的可预测性。
IF 4.8 2区 医学 Q1 Dentistry Pub Date : 2022-11-28 DOI: 10.1186/s40510-022-00438-z
Adriana Fiori, Giuseppe Minervini, Ludovica Nucci, Fabrizia d'Apuzzo, Letizia Perillo, Vincenzo Grassia

Background: To assess the predictability of crowding resolution and the efficacy of different strategies to gain space during clear aligners treatment.

Methods: A total of 10 clinicians were randomly recruited using the Doctor Locator by Align Technology (California). For each clinician, four consecutive patients treated with aligners and manual stripping were selected for a total of 40 subjects. Thus, 80 arches were collected and uploaded on the Orthoanalyzer software for arch measurements. The data were gained on the starting arch form (T0), on the virtual arch developed with digital planning (vT1), and on the arch form achieved at the end of the aligner sequences (T1). The following parameters were scored: Little's Irregularity Index, transversal arch diameters, (intercuspid, interpremolar, and intermolar width), incisor position/arch length, and enamel interproximal reduction (IPR).

Results: For all the measurements, statistically significant differences were found at different stages. The predictability of crowding resolution was very high, ranging from 87% in the upper arch and 81% in the lower one. Among the different strategies to gain space, variations in sagittal incisor position were predictable, with a value of 70% both in the upper and lower arch. Conversely, changes in arch diameters were less reliable varying between 49 and 67% in the lower arch and 59-83% in the upper one. Moreover, IPR was the least accurate procedure, wavering at 49% in the upper arch and 42% in the lower arch.

Conclusions: The predictability of crowding resolution during treatment with aligners was high. However, the virtual arch forms obtained at the end of digital planning (vT1) did not correspond with the arch forms at the end of the aligner sequences (T1). The IPR was the least predictable strategy to gain space, being, perhaps, an operator-dependent procedure.

背景:评估拥挤解决的可预测性和不同策略的有效性,以获得空间在清除矫形器治疗。方法:采用Align Technology (California)的医生定位器随机招募10名临床医生。对于每位临床医生,选择4名连续使用矫正器和手动剥离治疗的患者,共40名受试者。因此,我们收集了80个足弓,并将其上传到Orthoanalyzer软件中进行足弓测量。数据包括起始弓形(T0)、数字规划开发的虚拟弓形(vT1)和对准器序列结束时获得的弓形(T1)。对以下参数进行评分:Little's不规则指数,横弓直径,(尖牙间,解释磨牙,磨牙间宽度),切牙位置/弓长度,牙釉质近端间复位(IPR)。结果:各指标在不同阶段差异均有统计学意义。拥挤分辨率的可预测性很高,上弓为87%,下弓为81%。在获得空间的不同策略中,矢状切牙位置的变化是可预测的,上弓和下弓的变化值均为70%。相反,下弓直径的变化不太可靠,在49% - 67%之间,上弓在59-83%之间。此外,IPR是最不准确的手术,在上弓和下弓的摇摆率分别为49%和42%。结论:在使用矫正器治疗期间,拥挤解决的可预测性很高。然而,在数字规划(vT1)结束时获得的虚拟弓形与对准器序列(T1)结束时的弓形不一致。IPR是获得空间的最不可预测的策略,可能是一个依赖于操作人员的程序。
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引用次数: 9
Accuracy and stability of computer-aided customized lingual fixed retainer: a pilot study. 计算机辅助定制语言固定固位器的准确性和稳定性:一项试点研究。
IF 4.8 2区 医学 Q1 Dentistry Pub Date : 2022-11-21 DOI: 10.1186/s40510-022-00436-1
Seung-Hyun Kang, Jae-Sung Kwon, Chooryung Judi Chung, Jung-Yul Cha, Kee-Joon Lee

Background: With advances in digital technology, new types of lingual fixed retainers are being developed. However, there are few studies that quantitatively evaluate the accuracy and stability of lingual fixed retainers. The aim of this study was to assess the accuracy and stability of two types of computer-aided customized lingual fixed retainers and a conventional lingual fixed retainer.

Methods: A total of 10 maxillary and 10 mandibular duplicated dental models were selected, and then, three types of retainers were fabricated on the canine-to-canine area for each model. To evaluate accuracy, wire clearance at interproximal area (WCI) was measured using superimposition analysis. Initial flatness deformation was also measured for vertical distortion of retainers. Lateral width, anteroposterior length, and flatness deformation were measured at three-time points for stability assessment. Thermocycling was used to induce 6 months of time flow.

Results: The custom-bent group showed significantly higher WCI than the custom-cut and manual groups in the maxillary arch (P = 0.002). The custom-cut group showed significantly less flatness deformation, which was followed by the custom-bent and manual groups in both the maxillary and mandibular arch (P < 0.001). There was no significant difference in stability between the three retainer groups during 5100 cycles of thermocycling (corresponding to 6-month period).

Conclusions: Since there was no difference in stability between the three groups, it is recommended to use custom-cut type retainers in light of accuracy. However, accuracy and stability are not the only factors to consider when selecting type of retainers. Because each retainer has advantages and disadvantages, the type of retainers should be decided in consideration of the clinical environment.

背景:随着数字技术的进步,新型的语言固定固位器正在被开发。然而,定量评价舌固定固位器的准确性和稳定性的研究很少。本研究的目的是评估两种类型的计算机辅助定制舌固定固位器和传统舌固定固位器的准确性和稳定性。方法:选取10个上颌和10个下颌骨重复牙模型,分别在犬对犬区制作3种类型的固位体。为了评估准确性,采用叠加分析测量近端间区金属丝间隙(WCI)。初始平整度变形也测量了垂直变形的保持器。在三个时间点测量横向宽度,前后长度和平整度变形以进行稳定性评估。采用热循环法诱导6个月时间流。结果:自弯组上颌弓WCI明显高于自切组和手工组(P = 0.002)。自切组在上颌弓和下颌弓的平整度变形明显较小,自弯组次之,手动组次之(P)。结论:三组间稳定性无差异,从准确性考虑,推荐使用自切型固位器。然而,精度和稳定性并不是选择固位器类型时要考虑的唯一因素。由于每一种固位体都有其优点和缺点,所以在选择固位体的类型时应结合临床环境来考虑。
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引用次数: 0
Different biomechanical effects of clear aligners in bimaxillary space closure under two strong anchorages: finite element analysis. 两种强支抗下透明矫正器在双颌间隙闭合中的不同生物力学效应:有限元分析。
IF 4.8 2区 医学 Q1 Dentistry Pub Date : 2022-11-14 DOI: 10.1186/s40510-022-00435-2
Jun-Qi Liu, Guan-Yin Zhu, Yi-Gan Wang, Bo Zhang, Shuang-Cheng Wang, Ke Yao, Zhi-He Zhao

Background: Clear aligner (CA) treatment has been gaining popularity, but the biomechanical effects of CAs in bimaxillary dentition have not been thoroughly investigated. Direct and indirect strong anchorages are two common anchorage control methods, but the underlying biomechanical mechanism has not yet been elucidated. This study aimed to investigate the different biomechanical effects of CAs in closing the bimaxillary space under different anchorage controls, further instructing the compensation strategies design and strong anchorage choice in clinical practice.

Methods: Three-dimensional (3D) bimaxillary models of different anchorage controls were created based on cone-beam computed tomography and intraoral scan data. Four first premolars were extracted using 3D modeling software. Finite element analysis was conducted to simulate the space closure process of the CAs.

Results: In the two strong anchorage groups, the bimaxillary dentition presented different movement patterns during the space closure process, and the lower dentition was more vulnerable to elastic force. From the vertical view, direct strong anchorage with elastic force had the advantage of flattening the longitudinal occlusal curve and resisting the roller-coaster effects, whereas indirect strong anchorage could lead to a deep longitudinal occlusal curve. From the sagittal view, indirect strong anchorage with metallic ligaments had a greater instantaneous anchorage protection effect, particularly in the lower dentition, which reduced the mesial movement of the posterior teeth by nearly four times that of the direct anchorage group. In addition, indirect strong anchorage presented better anterior teeth torque/tipping control, while direct strong anchorage could aggravate lingual tipping of the upper central incisors. Due to the differences in anterior-posterior anchorage and arch shape, compared with the upper dentition, anchorage preservation and vertical control effects were amplified in the lower dentition.

Conclusions: The biomechanical effects of CAs differed between the two strong anchorage groups. Due to the differences in dentition morphology, anterior-posterior anchorage, and dental arch shape, CAs present different biomechanical effects in bimaxillary space closure. Orthodontists should consider the corresponding mechanical compensation according to specific anchorage control methods and dentitions.

背景:清除矫正器(Clear aligner, CA)治疗已越来越受欢迎,但其在双颌牙列中的生物力学效应尚未得到深入研究。直接强锚固和间接强锚固是常用的两种锚固控制方法,但其生物力学机制尚未阐明。本研究旨在探讨不同支抗控制下ca对双颌间隙闭合的不同生物力学效应,为临床实践中补偿策略的设计和强支抗的选择提供指导。方法:基于锥形束计算机断层扫描和口内扫描数据,建立不同支抗对照的双颌三维模型。采用三维建模软件拔除4颗第一前磨牙。采用有限元方法模拟了CAs的空间闭合过程。结果:在两组强支抗中,双颌牙列在空间闭合过程中表现出不同的运动模式,下牙列更容易受到弹性力的影响。从纵向上看,直接强锚固具有弹性力的优势,可以使纵向咬合曲线变平坦,抵抗过山车效应,而间接强锚固可能导致纵向咬合曲线变深。从矢状面来看,金属韧带间接强支抗具有更大的瞬时支抗保护效果,特别是在下牙列,使后牙近近距离运动减少了直接支抗组的近4倍。间接强支抗能较好地控制前牙的扭矩/倾翻,而直接强支抗会加重上中切牙的舌倾。由于前后支抗和牙弓形状的差异,与上牙列相比,下牙列的支抗保存和垂直控制作用被放大。结论:两强支具组间ca的生物力学效应存在差异。由于牙列形态、前后支抗和牙弓形状的差异,ca在双颌间隙闭合中表现出不同的生物力学效应。正畸医师应根据具体的支抗控制方法和牙列考虑相应的机械补偿。
{"title":"Different biomechanical effects of clear aligners in bimaxillary space closure under two strong anchorages: finite element analysis.","authors":"Jun-Qi Liu,&nbsp;Guan-Yin Zhu,&nbsp;Yi-Gan Wang,&nbsp;Bo Zhang,&nbsp;Shuang-Cheng Wang,&nbsp;Ke Yao,&nbsp;Zhi-He Zhao","doi":"10.1186/s40510-022-00435-2","DOIUrl":"https://doi.org/10.1186/s40510-022-00435-2","url":null,"abstract":"<p><strong>Background: </strong>Clear aligner (CA) treatment has been gaining popularity, but the biomechanical effects of CAs in bimaxillary dentition have not been thoroughly investigated. Direct and indirect strong anchorages are two common anchorage control methods, but the underlying biomechanical mechanism has not yet been elucidated. This study aimed to investigate the different biomechanical effects of CAs in closing the bimaxillary space under different anchorage controls, further instructing the compensation strategies design and strong anchorage choice in clinical practice.</p><p><strong>Methods: </strong>Three-dimensional (3D) bimaxillary models of different anchorage controls were created based on cone-beam computed tomography and intraoral scan data. Four first premolars were extracted using 3D modeling software. Finite element analysis was conducted to simulate the space closure process of the CAs.</p><p><strong>Results: </strong>In the two strong anchorage groups, the bimaxillary dentition presented different movement patterns during the space closure process, and the lower dentition was more vulnerable to elastic force. From the vertical view, direct strong anchorage with elastic force had the advantage of flattening the longitudinal occlusal curve and resisting the roller-coaster effects, whereas indirect strong anchorage could lead to a deep longitudinal occlusal curve. From the sagittal view, indirect strong anchorage with metallic ligaments had a greater instantaneous anchorage protection effect, particularly in the lower dentition, which reduced the mesial movement of the posterior teeth by nearly four times that of the direct anchorage group. In addition, indirect strong anchorage presented better anterior teeth torque/tipping control, while direct strong anchorage could aggravate lingual tipping of the upper central incisors. Due to the differences in anterior-posterior anchorage and arch shape, compared with the upper dentition, anchorage preservation and vertical control effects were amplified in the lower dentition.</p><p><strong>Conclusions: </strong>The biomechanical effects of CAs differed between the two strong anchorage groups. Due to the differences in dentition morphology, anterior-posterior anchorage, and dental arch shape, CAs present different biomechanical effects in bimaxillary space closure. Orthodontists should consider the corresponding mechanical compensation according to specific anchorage control methods and dentitions.</p>","PeriodicalId":56071,"journal":{"name":"Progress in Orthodontics","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2022-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9659682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40684857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Predictability of lower incisor tip using clear aligner therapy. 使用透明矫正器治疗下门牙尖的可预测性。
IF 4.8 2区 医学 Q1 Dentistry Pub Date : 2022-11-07 DOI: 10.1186/s40510-022-00433-4
Julia Meri Smith, Tony Weir, Austin Kaang, Mauro Farella

Background: Uprighting incisors is particularly important with clear aligner therapy as incisor tip determines the mesio-distal space needed in the arch, and consequently the fit of the aligner. The objective of this study was to investigate the accuracy of ClinCheck® software to predict lower incisor tip by comparing digitally prescribed movements with actual clinical outcomes and to determine whether the presence of a vertically orientated rectangular composite attachment influences the efficacy of incisor tip.

Methodology: This retrospective study included 66 lower incisors from 42 non-extraction adult patients treated using the Invisalign® appliance. Twenty-one incisors had vertical attachments, while 45 incisors did not have any attachments. Lower incisor tip was measured at T0 (pre-treatment), T1 (predicted post-treatment) and T2 (achieved post-treatment) on digital models using metrology software. The change in position from T0 to T1 and T0 to T2 was measured from the estimated centre of resistance (CRes) of each tooth. The estimated centre of rotation was plotted relative to the CRes to describe the type of orthodontic tooth movement (OTM) predicted and achieved.

Results: Predicted incisor tip and achieved incisor tip were positively correlated (R2 = 0.55; p < 0.001). For every degree of tip planned 0.4 degrees of tip was achieved. The presence of an attachment resulted in 1.2 degrees greater tip (F = 3.7; p = 0.062) and 0.5 mm greater movement of the predicted apex of the tooth (F = 4.3; p = 0.042) compared with the no attachment group. The type of OTM achieved differed from the type predicted. Sixty-seven percent of incisors investigated were predicted to move by root movement, while 46% achieved this type of movement.

Conclusions: The amount of lower incisor tip achieved was on average substantially less than the ClinCheck® displayed. Vertically orientated rectangular attachments are recommended where large root movement is planned, and their presence slightly improves apex movement.

背景:由于切牙尖端决定了弓中-远端空间的需要,从而决定了矫正器的贴合,因此矫正门牙在明确矫正器治疗中尤为重要。本研究的目的是通过比较数字规定的运动与实际临床结果来研究ClinCheck®软件预测下门牙尖的准确性,并确定垂直定向矩形复合附着体的存在是否会影响门牙尖的疗效。方法:本回顾性研究包括42例使用Invisalign®矫治器治疗的未拔牙成人患者的66个下门牙。21个门牙有垂直附着体,45个门牙无附着体。使用计量软件在数字模型上测量T0(预处理)、T1(预测的后处理)和T2(实现的后处理)的下门牙尖。从每颗牙的估计阻力中心(cre)测量T0到T1和T0到T2的位置变化。估计的旋转中心相对于cre绘制,以描述预测和实现的正畸牙齿运动(OTM)的类型。结果:预测切牙尖与实际切牙尖呈正相关(R2 = 0.55;p结论:达到的下切牙尖的数量平均比ClinCheck®显示的少得多。垂直定向的矩形附着物建议在大的根运动计划,他们的存在略微改善顶端运动。
{"title":"Predictability of lower incisor tip using clear aligner therapy.","authors":"Julia Meri Smith,&nbsp;Tony Weir,&nbsp;Austin Kaang,&nbsp;Mauro Farella","doi":"10.1186/s40510-022-00433-4","DOIUrl":"https://doi.org/10.1186/s40510-022-00433-4","url":null,"abstract":"<p><strong>Background: </strong>Uprighting incisors is particularly important with clear aligner therapy as incisor tip determines the mesio-distal space needed in the arch, and consequently the fit of the aligner. The objective of this study was to investigate the accuracy of ClinCheck<sup>®</sup> software to predict lower incisor tip by comparing digitally prescribed movements with actual clinical outcomes and to determine whether the presence of a vertically orientated rectangular composite attachment influences the efficacy of incisor tip.</p><p><strong>Methodology: </strong>This retrospective study included 66 lower incisors from 42 non-extraction adult patients treated using the Invisalign<sup>®</sup> appliance. Twenty-one incisors had vertical attachments, while 45 incisors did not have any attachments. Lower incisor tip was measured at T0 (pre-treatment), T1 (predicted post-treatment) and T2 (achieved post-treatment) on digital models using metrology software. The change in position from T0 to T1 and T0 to T2 was measured from the estimated centre of resistance (C<sub>Res</sub>) of each tooth. The estimated centre of rotation was plotted relative to the C<sub>Res</sub> to describe the type of orthodontic tooth movement (OTM) predicted and achieved.</p><p><strong>Results: </strong>Predicted incisor tip and achieved incisor tip were positively correlated (R<sup>2</sup> = 0.55; p < 0.001). For every degree of tip planned 0.4 degrees of tip was achieved. The presence of an attachment resulted in 1.2 degrees greater tip (F = 3.7; p = 0.062) and 0.5 mm greater movement of the predicted apex of the tooth (F = 4.3; p = 0.042) compared with the no attachment group. The type of OTM achieved differed from the type predicted. Sixty-seven percent of incisors investigated were predicted to move by root movement, while 46% achieved this type of movement.</p><p><strong>Conclusions: </strong>The amount of lower incisor tip achieved was on average substantially less than the ClinCheck<sup>®</sup> displayed. Vertically orientated rectangular attachments are recommended where large root movement is planned, and their presence slightly improves apex movement.</p>","PeriodicalId":56071,"journal":{"name":"Progress in Orthodontics","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2022-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9637687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40682365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Qualitative and quantitative three-dimensional evaluation of maxillary basal and dentoalveolar dimensions in patients with and without maxillary impacted canines. 有上颌阻生牙和没有上颌阻生牙的患者上颌基牙和牙槽牙尺寸的定性和定量三维评价。
IF 4.8 2区 医学 Q1 Dentistry Pub Date : 2022-10-24 DOI: 10.1186/s40510-022-00434-3
Hasan M Sharhan, Abeer A Almashraqi, Hanan Al-Fakeh, Najah Alhashimi, Ehab A Abdulghani, Wenyuanfeng Chen, Abeer A Al-Sosowa, BaoCheng Cao, Maged S Alhammadi

Background: This study aimed to three-dimensionally evaluate the qualitative and quantitative maxillary basal, dentoalveolar, and dental dimensions in patients with unilateral or bilateral maxillary impacted canines relative to their normal peers.

Materials and methods: This is a retrospective comparative study. Cone-beam computed tomography images of one hundred and fifty adult patients were divided into three equal groups: unilateral, bilateral, and control groups. Each had 50 patients that were three-dimensionally analysed. The quantitative measurements involved three basal (molar basal width, premolar basal width, and arch depth), seven dentoalveolar (molar alveolar width, premolar alveolar width, inter-molar width, inter-premolar width, inter-canine width, arch length, and arch perimeter), and two dental (canine length and width) measurements. The qualitative measurements included four bone density areas (buccal, lingual, mesial, and distal) around the maxillary impacted canines.

Result: Differences between the three groups were statistically different for the quantitative measurements involving the two basal variables (molar basal width and premolar basal width) and all measured dentoalveolar variables; these were smaller in the unilateral and bilateral groups compared with the control group (p < 0.001). Unilateral and bilateral impacted canine groups showed significantly wider and shorter canines than the control group (p < 0.001). The qualitative measurements (the four bone density areas) around unilateral and bilateral impacted canine groups showed significantly greater density than the control group (p < 0.001). There was no significant qualitative or quantitative difference between the unilateral and bilateral impacted canines. The three groups had no significant variations in terms of arch depth.

Conclusion: Maxillary unilateral and bilateral canine impactions are associated with reduced basal and dentoalveolar dimensions as well as wider and shorter maxillary canines compared to normal peers. The quality of bone around unilateral and bilateral impacted maxillary canines is higher than in non-impacted cases. Unilateral and bilateral canine impactions have quite similar qualitative and quantitative parameters.

背景:本研究旨在对单侧或双侧上颌阻生犬患者的上颌基牙、牙槽牙和牙齿尺寸进行定性和定量的三维评估。材料与方法:回顾性比较研究。将150例成人患者的锥束计算机断层图像分为三组:单侧组、双侧组和对照组。每组有50名患者进行三维分析。定量测量包括三个基础(臼齿基础宽度,前臼齿基础宽度和弓深度),七个牙槽(臼齿牙槽宽度,前臼齿牙槽宽度,臼齿间宽度,前臼齿间宽度,齿间宽度,弓长度和弓周长)和两个牙齿(犬齿长度和宽度)测量。定性测量包括上颌阻生犬周围的四个骨密度区(颊、舌、中、远端)。结果:三组间在两个基牙变量(磨牙基牙宽度和前磨牙基牙宽度)和所有测量的牙槽牙变量的定量测量上差异均有统计学意义;结论:与正常同龄人相比,上颌单侧和双侧牙嵌塞与基牙和牙槽尺寸减小以及上颌牙宽和短有关。单侧和双侧阻生上颌犬齿周围的骨质量高于非阻生病例。单侧和双侧犬嵌塞具有相当相似的定性和定量参数。
{"title":"Qualitative and quantitative three-dimensional evaluation of maxillary basal and dentoalveolar dimensions in patients with and without maxillary impacted canines.","authors":"Hasan M Sharhan,&nbsp;Abeer A Almashraqi,&nbsp;Hanan Al-Fakeh,&nbsp;Najah Alhashimi,&nbsp;Ehab A Abdulghani,&nbsp;Wenyuanfeng Chen,&nbsp;Abeer A Al-Sosowa,&nbsp;BaoCheng Cao,&nbsp;Maged S Alhammadi","doi":"10.1186/s40510-022-00434-3","DOIUrl":"https://doi.org/10.1186/s40510-022-00434-3","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to three-dimensionally evaluate the qualitative and quantitative maxillary basal, dentoalveolar, and dental dimensions in patients with unilateral or bilateral maxillary impacted canines relative to their normal peers.</p><p><strong>Materials and methods: </strong>This is a retrospective comparative study. Cone-beam computed tomography images of one hundred and fifty adult patients were divided into three equal groups: unilateral, bilateral, and control groups. Each had 50 patients that were three-dimensionally analysed. The quantitative measurements involved three basal (molar basal width, premolar basal width, and arch depth), seven dentoalveolar (molar alveolar width, premolar alveolar width, inter-molar width, inter-premolar width, inter-canine width, arch length, and arch perimeter), and two dental (canine length and width) measurements. The qualitative measurements included four bone density areas (buccal, lingual, mesial, and distal) around the maxillary impacted canines.</p><p><strong>Result: </strong>Differences between the three groups were statistically different for the quantitative measurements involving the two basal variables (molar basal width and premolar basal width) and all measured dentoalveolar variables; these were smaller in the unilateral and bilateral groups compared with the control group (p < 0.001). Unilateral and bilateral impacted canine groups showed significantly wider and shorter canines than the control group (p < 0.001). The qualitative measurements (the four bone density areas) around unilateral and bilateral impacted canine groups showed significantly greater density than the control group (p < 0.001). There was no significant qualitative or quantitative difference between the unilateral and bilateral impacted canines. The three groups had no significant variations in terms of arch depth.</p><p><strong>Conclusion: </strong>Maxillary unilateral and bilateral canine impactions are associated with reduced basal and dentoalveolar dimensions as well as wider and shorter maxillary canines compared to normal peers. The quality of bone around unilateral and bilateral impacted maxillary canines is higher than in non-impacted cases. Unilateral and bilateral canine impactions have quite similar qualitative and quantitative parameters.</p>","PeriodicalId":56071,"journal":{"name":"Progress in Orthodontics","volume":null,"pages":null},"PeriodicalIF":4.8,"publicationDate":"2022-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9588850/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40674634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
期刊
Progress in Orthodontics
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