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O.7.2 RADIOBIOLOGICAL EFFECTS OF PROTONS OR GAMMA RAYS AND UVB RADIATION ON HUMAN CELLS O.7.2 质子或伽马射线和紫外线辐射对人体细胞的放射生物学效应
IF 3.3 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Physica Medica-European Journal of Medical Physics
Pub Date : 2024-11-01 DOI: 10.1016/j.ejmp.2024.104567
A. Gkikoudi, S.N. Vasilopoulos, C. Beinke, A. Al-Qaaod, U. Giesen, F. Krasniqi, G.I. Terzoudi, A.G. Georgakilas
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引用次数: 0
Assessment of pencil beam scanning proton therapy beam delivery accuracy through machine learning and log file analysis 通过机器学习和日志文件分析评估铅笔束扫描质子疗法的束流输送准确性。
IF 3.3 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Physica Medica-European Journal of Medical Physics
Pub Date : 2024-11-01 DOI: 10.1016/j.ejmp.2024.104854
Ranjith C.P. , Mayakannan Krishnan , Vysakh Raveendran , Lalit Chaudhari , Siddhartha Laskar

Purpose

Comprehensive Quality Assurance (QA) protocols are necessary for complex beam delivery systems like Pencil Beam Scanning (PBS) proton therapy. This study focuses on automating the evaluation of beam delivery accuracy using irradiation log files and machine learning (ML) models.

Methods

Irradiation log files of 935 clinical treatment fields and routine QA beams were analysed to evaluate spot parameters and Monitor Unit (MU) accuracy. ML models predicted spot size along the X, Y, major, and minor axes. In-house scripts automated log file analysis and spot size predictions. Predicted spot sizes were compared with expected baselines, and the accuracy of spot position, symmetry, and MU for each spot in the beam was evaluated.

Results

More than 99.5 % of spot positions were accurate within a 1 mm. The mean and Standard Deviation (SD) of X positional error were −0.021 mm (SD: 0.181 mm), and for Y positional error, they were −0.002 mm (SD: 0.132 mm). ML models accurately predicted spot sizes, with over 95 % of spots demonstrating size variations within 10 % of the baseline. The Root Mean Squared Error (RMSE) of X and Y spot size differences were 0.15 mm and 0.16 mm, respectively. Spot symmetry was within 10 %, and MU accuracy showed 95 % of spots with MU per spot variation less than 2 %.

Conclusion

This method can validate the vendor’s beam delivery safety interlock system and serve as a quick alternative to patient-specific QA in adaptive treatment, where time is limited, as well as for routine QA spot parameter evaluations.
目的：对于像铅笔束扫描（PBS）质子治疗这样复杂的射束传输系统，全面的质量保证（QA）协议是必要的。本研究的重点是利用辐照日志文件和机器学习（ML）模型自动评估射束传输的准确性：方法：分析了935个临床治疗场和常规QA束的辐照记录文件，以评估光斑参数和监测单元（MU）的准确性。ML 模型沿 X、Y、主轴和次轴预测光斑大小。内部脚本自动进行日志文件分析和光斑大小预测。将预测的光斑尺寸与预期基线进行比较，并评估光束中每个光斑的光斑位置、对称性和 MU 的准确性：结果：99.5% 以上的光斑位置精确度在 1 毫米以内。X 位置误差的平均值和标准偏差（SD）分别为-0.021 毫米（SD：0.181 毫米），Y 位置误差的平均值和标准偏差（SD）分别为-0.002 毫米（SD：0.132 毫米）。ML 模型能准确预测光斑尺寸，95% 以上的光斑尺寸变化在基线的 10% 以内。X 和 Y 光斑尺寸差异的均方根误差（RMSE）分别为 0.15 毫米和 0.16 毫米。光斑对称性在 10% 以内，MU 精确度显示 95% 的光斑每个光斑的 MU 变化小于 2%：该方法可验证供应商的光束传输安全联锁系统，在时间有限的适应性治疗中可快速替代针对患者的质量检测，也可用于常规质量检测光斑参数评估。
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引用次数: 0
O.5.4 THE SYNERGETIC ROLE OF CHEMICAL EXCHANGE SATURATION TRANSFER (CEST) IN THE MR IMAGING OF BRAIN TUMORS O.5.4 化学交换饱和转移（CEST）在脑肿瘤 mr 成像中的协同作用
IF 3.3 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Physica Medica-European Journal of Medical Physics
Pub Date : 2024-11-01 DOI: 10.1016/j.ejmp.2024.104555
I. Ioannidis, D. Gkotsis, E. Gkotsis, A. Celik, E. Kapsalaki, I. Seimenis, G. Velonakis
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引用次数: 0
O.9.2 SELF-ASSEMBLED NANOSYSTEMS EXHIBITING ENHANCED FLUORESCENCE: COMPLEXATION OF AN AMINO TERPOLYMER AND ITS QUATERNIZED ANALOGUE WITH AGGREGATION-INDUCED EMISSION (AIE) DYE O.9.2 显示增强荧光的自组装纳米系统：氨基三元共聚物及其季铵化类似物与聚集诱导发光（AIE）染料的复合物
IF 3.3 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Physica Medica-European Journal of Medical Physics
Pub Date : 2024-11-01 DOI: 10.1016/j.ejmp.2024.104573
M.A. Pantelaiou, D. Vagenas, E.S. Karvelis, G. Rotas, S. Pispas
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引用次数: 0
PP.3.3 COMPARISON OF 18F-PSMA-1007 WITH 18F-CHOLINE PET/CT IN PROSTATE CANCER RECURRENCE, USING QUANTITATIVE BIOMARKERS pp.3.3 使用定量生物标记物比较 18f-psma-1007 与 18f-choline pet/ct 在前列腺癌复发中的作用
IF 3.3 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Physica Medica-European Journal of Medical Physics
Pub Date : 2024-11-01 DOI: 10.1016/j.ejmp.2024.104592
S. Andreou, E. Panagiotidis, K. Aggeioplasti, A. Paschali, A. Makridou, I. Datseris, V. Chatzipavlidou, E. Papanastasiou
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引用次数: 0
PP.1.8 QUALITY OF LIFE ASSESSMENT IN HEAD AND NECK CANCER PATIENTS UNDERGOING MODERN RADIOTHERAPY TECHNIQUES: EVALUATING AND CORRELATING DOSIMETRY AND TOXICITY FINDINGS pp.1.8 接受现代放射治疗技术的头颈部癌症患者的生活质量评估：剂量测定和毒性结果的评估与关联
IF 3.3 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Physica Medica-European Journal of Medical Physics
Pub Date : 2024-11-01 DOI: 10.1016/j.ejmp.2024.104585
P. Kiafi, M.A. Kouri, G. Patatoukas, O. Nicolatou-Galitis, M. Chalkia, A. Kougioumtzopoulou, V. Kouloulias, K. Platoni
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引用次数: 0
PP.2.1 IMPLEMENTATION OF A RADIATION EXPOSURE MONITORING PROGRAMME IN MEDICAL IMAGING: PRELIMINARY RESULTS FROM A LARGE HOSPITAL GROUP pp.2.1 实施医学影像辐射监测计划：一家大型医院集团的初步结果
IF 3.3 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Physica Medica-European Journal of Medical Physics
Pub Date : 2024-11-01 DOI: 10.1016/j.ejmp.2024.104586
E. Skouridi, N. Fitousi, D. Kaolis, V. Metaxas
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引用次数: 0
PP.6.2 COMPUTER-AIDED DIAGNOSIS SYSTEM FOR BREAST LESION DETECTION IN DCE-MRI USING OTSU'S MULTILEVEL THRESHOLDING 第 6.2 页 利用大津多级阈值法检测 DCE-MRI 中乳腺病变的计算机辅助诊断系统
IF 3.3 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Physica Medica-European Journal of Medical Physics
Pub Date : 2024-11-01 DOI: 10.1016/j.ejmp.2024.104606
T. Andreadis, K. Chouchos, N. Courcoutsakis, I. Seimenis, D. Koulouriotis
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引用次数: 0
PP.1.4 ON THE DOSIMETRIC EFFECT OF VIRTUAL BOLUS FOR SUPERFICIAL TUMORS TREATED USING HELICAL TOMOTHERAPY pp.1.4 虚拟栓剂对使用螺旋断层疗法治疗浅表肿瘤的剂量学影响
IF 3.3 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Physica Medica-European Journal of Medical Physics
Pub Date : 2024-11-01 DOI: 10.1016/j.ejmp.2024.104581
P. Archontakis, A. Moutsatsos, A. Stergioula, L. Sideri, K. Salvara, E. Pantelis
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引用次数: 0
O.1.6 A COMPARATIVE ANALYSIS OF VOLUMETRIC MODULATED ARC THERAPY (VMAT) AND DYNAMIC CONFORMAL ARC (DCA) TECHNIQUES FOR LINAC-BASED STEREOTACTIC RADIOTHERAPY OF SINGLE BRAIN METASTASES o.1.6 容积调制弧形疗法（vmat）和动态适形弧形疗法（dca）技术在基于线性加速器的单个脑转移瘤立体定向放射治疗中的比较分析
IF 3.3 3区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Physica Medica-European Journal of Medical Physics
Pub Date : 2024-11-01 DOI: 10.1016/j.ejmp.2024.104532
D. Stasinou, M. Psarras, T. Stroubinis, M. Protopapa, D. Alexiou, A. Zygogianni, V. Kouloulias, K. Platoni
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引用次数: 0
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