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Characterizing Cognitive Dispersion and Its Correlates Across the Adult Lifespan in MIDUS. MIDUS成年期认知分散特征及其相关因素。
IF 3.2 2区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-05-08 DOI: 10.1093/geronb/gbae201
Laura M Klepacz, Eric S Cerino, Jeremy M Hamm

Objectives: Although research has shown that higher levels of within-person variability across cognitive tasks (dispersion) are associated with cognitive decline in clinical samples, little is known about dispersion in comparatively younger, nonclinical, and national samples. A better understanding of dispersion is needed to elucidate for whom and under what circumstances dispersion can be used as a reliable indicator of cognitive health.

Method: We used data from the Midlife in the United States Study (MIDUS; n = 2,229; Mage = 56 years, range = 33-83; 56% female) to: (a) characterize dispersion and its cross-sectional correlates in a nonclinical, adult lifespan sample and (b) examine changes in dispersion over time to determine for whom changes in dispersion may reflect better or worse cognitive aging.

Results: Correlations showed higher levels of dispersion were associated with higher levels of mean performance at both waves (rs = 0.28-0.29). Autoregressive main effect models showed that increases in dispersion were associated with less decline in mean performance over the 2-wave, 9-year follow-up period (β = 0.17, p < .001). Moderation models showed that the link between change in dispersion and change in mean performance was pronounced in comparatively older adults (β = 0.28), women (β = 0.27), individuals with less education (β = 0.23), and those with lower income (β = 0.23; all ps < .001).

Discussion: Findings suggest that increases in dispersion may not always be maladaptive in normative, adult lifespan samples and may reflect healthier cognitive profiles in individuals who are at greater risk for cognitive impairment.

目的:尽管研究表明,临床样本中认知任务中较高水平的人内变异性(离散度)与认知能力下降有关,但对相对年轻、非临床和国家样本中的离散度知之甚少。需要更好地了解离散度,以阐明在何种情况下离散度可以作为认知健康的可靠指标。方法:我们使用了美国中年人研究(MIDUS;N = 2229;法师= 56岁,射程= 33-83;(56%女性)来:(a)表征离散度及其在非临床成年寿命样本中的横断面相关性;(b)检查离散度随时间的变化,以确定离散度的变化可能反映认知衰老的好坏。结果:相关性显示,在两个波中,较高水平的分散与较高水平的平均表现相关(rs = 0.28 - 0.29)。自回归主效应模型显示,在两波9年随访期间,离散度的增加与平均表现的较小下降相关(β = 0.17, p < 0.001)。适度模型显示,在年龄较大的成年人(β = 0.28)、女性(β = 0.27)、受教育程度较低的个体(β = 0.23)和收入较低的个体(β = 0.23)中,分散度变化与平均表现变化之间的联系较为明显(所有ps < 0.001)。讨论:研究结果表明,在规范的成年寿命样本中,离散度的增加可能并不总是适应不良,可能反映出认知障碍风险较高的个体的认知状况更健康。
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引用次数: 0
Within- and Between-Person Differences in Activity Factor Structure: Results From an Ecological Momentary Assessment Study. 活动因子结构的人内与人间差异:一项生态瞬时评价研究的结果。
IF 4.8 2区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-04-07 DOI: 10.1093/geronb/gbaf017
Allison A M Bielak, Jacqueline A Mogle, Martin J Sliwinski

Objectives: Studies using ecological momentary assessment (EMA) of activity participation rely on items tapping domains informed by factor analyses based on single time points. Analyses from a single time point focus on differences between participants and provide little insight into how activities cluster together within a person across moments or days. The present study compared the factor structure in activity participation between- and within-persons using an expanded set of momentary activity items in middle and older adulthood.

Methods: Using tablets, 81 adults aged 41 to 94 years reported activities completed in the past 3-4 hr 5 times per day for 14 days.

Results: The most common activities during the day involved social interactions, reading, and computer work. Watching TV or videos was the most common evening activity. Multilevel factor analysis simultaneously computed both intra-individual factors (within-person) and inter-individual factors (between-person). Four within-person and 4 between-person factors provided the best model fit, with 3 common factors: cognitive (read, computer); social (events, mentoring, providing care); and passive (TV, games). There were notable differences in the fourth factor.

Discussion: Although three common activity factors were found between individuals and within persons from day to day, the divergence between the fourth intra- and inter-individual factors provides insight into how activity engagement operates at different timescales and likely reflects daily demands versus long-term goals. EMA provides a window into engagement throughout and across days, but researchers who commonly use retrospective reports of between-person activity engagement may find distinctly different results from factor analyses.

目的:利用活动参与的生态瞬间评估(EMA)的研究依赖于基于单一时间点的因子分析所告知的项目挖掘域。从单个时间点进行的分析侧重于参与者之间的差异,并不能深入了解一个人在几分钟或几天内的活动是如何聚集在一起的。本研究采用一套扩展的瞬间活动项目,比较了中老年人活动参与的人际和内部因素结构。方法:使用片剂,81名41 - 94岁的成年人报告在过去3-4小时内完成活动,每天5次,持续14天。结果:白天最常见的活动包括社交、阅读和电脑工作。看电视或视频是最常见的夜间活动。多层次因素分析同时计算个体内因素(人内因素)和个体间因素(人间因素)。4个人内因素和4个人之间因素提供了最佳的模型拟合,其中有三个常见因素:认知(阅读、计算机);社交(活动、指导、提供照顾);被动因素(电视、游戏)。在第四个因素上存在显著差异。讨论:尽管在个体之间和个体内部每天都发现了三个共同的活动因素,但第四种个体内部和个体间因素之间的差异提供了对活动参与在不同时间尺度上如何运作的洞察,并可能反映日常需求与长期目标。EMA提供了全天和跨天参与的窗口,但通常使用人际活动参与回顾性报告的研究人员可能会从因素分析中发现明显不同的结果。
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引用次数: 0
The Impact of Stepfamily Structure on Older Parents' Frequency of Contact With and Care Receipt From Adult Biological and Stepchildren in the Netherlands. 继家庭结构对荷兰成年亲生子女和继子女接触频率和照顾接收的影响。
IF 4.8 2区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-04-07 DOI: 10.1093/geronb/gbaf015
Suzan van der Pas, Theo G van Tilburg

Objectives: Older people are increasingly entering their later years in stepfamilies. Because adult children play a central role in older parents' support networks, there is concern that the generally weaker intergenerational ties found in stepfamilies may imply an impending deficit in the care available to stepparents. It is currently unclear whether there are differences across stepfamily types including stepfamilies with only biological children. The aim of the study is to examine whether there are differences in contact frequency with and care receipt from adult biological and stepchildren in biological and different types of stepfamilies.

Methods: Data are from the Longitudinal Aging Study Amsterdam (1992-2022; 10 observations); respondents' ages varied between 54 and 101. An average of 3.7 observations are available from 2,761 parents in biological families and 647 parents in stepfamilies.

Results: Parents in biological families and in stepfamilies with joint children had more contact than in other stepfamily types. There was less contact in stepfamilies with biological and stepchildren formed in midlife and in families with only stepchildren. There were small differences in care receipt; the lowest likelihood was in composite families.

Discussion: Our study challenges the idea that the relationships of the adult child to older parents in all stepfamilies are weaker than in biological families and points to the importance of considering that only some stepfamilies are vulnerable in terms of contact frequency. We query whether stepfamilies are resilient, for example, to greater pressures from a sharp increase in care needs for one or both parents.

目的:越来越多的老年人进入晚年后加入了继父继母的家庭。由于成年子女在老年父母的支持网络中扮演着核心角色,人们担心继家庭中的代际联系普遍较弱,这可能意味着继父母即将无法获得足够的照顾。目前还不清楚不同类型的继家庭(包括只有亲生子女的继家庭)之间是否存在差异。本研究旨在探讨在亲生和不同类型的继家庭中,成年亲生子女和继子女在接触频率和接受照顾方面是否存在差异:数据来自阿姆斯特丹老龄化纵向研究(1992-2022 年;10 次观察);受访者年龄在 54 岁至 101 岁之间。从 2,761 名亲生父母和 647 名继父继母那里平均获得了 3.7 个观测数据:与其他类型的继家庭相比,亲生家庭和有共同子女的继家庭中的父母有更多的接触。在有亲生子女和中年继子女的继家庭以及只有继子女的家庭中,接触较少。在接受照顾方面差异较小;复合型家庭接受照顾的可能性最低:我们的研究对所有继子女家庭中成年子女与年长父母的关系都弱于亲生父母家庭的观点提出了质疑,并指出考虑到只有部分继子女家庭在接触频率方面处于弱势的重要性。我们对继父继母家庭是否具有承受力提出了质疑,例如,继父继母是否能够承受父母一方或双方的护理需求急剧增加所带来的更大压力。
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引用次数: 0
War Trauma and Strength: A Qualitative Study of Participants in the Vietnamese Insights into Cognitive Aging Program. 战争创伤与力量:越南认知老化项目(VIP)参与者的质性研究。
IF 4.8 2区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-04-07 DOI: 10.1093/geronb/gbaf019
Uyen T M Vu, Sarah Tomaszewski Farias, Ladson Hinton, Van T Park, Quyen Q Tiet, Rachel A Whitmer, Sierra Heuer, Boi-San Nguyen, Oanh L Meyer

Objectives: Vietnamese Americans are the fourth largest Asian subgroup in the United States, but little qualitative work has been done on their war and migration experiences. In this study, we delineated the war-related traumas and strength in participants of the Vietnamese Insights into Cognitive Aging Program (VIP).

Methods: VIP is a longitudinal study of 548 Vietnamese Americans aged 65+ years living in Northern California. During Visit 1, a semi-structured interview was conducted on participants' life and experiences in Vietnam and immigration to the United States. Using data at one of the recruitment sites, interviews of participants having the highest total self-reported traumas were transcribed in Vietnamese (n = 43) for coding and analysis following a thematic approach.

Results: Participants were 73.2 years old on average (SD = 5.48). Most were male (67.4%) and had attempted to escape Vietnam by boat at least once (67%). Two major themes were found: (1) experiences of adversity and suffering, which included subthemes on tough life experiences during the war, imprisonment and hard life after the war, escaping by boat and living in the refugee camps, witnessing or hearing about others' traumas during the war and escape, and experiences of loss, and (2) personal fortitude and gratitude, which included subthemes on fortitude and endurance, personal skills to cope and navigate, and perceived "luck and blessings."

Discussion: Results from this study revealed various traumas and aspects of strength. These findings can contribute to future VIP research on cognitive aging and inform research and practice on health disparities.

目的:越南裔美国人是美国第四大亚裔群体,但关于他们的战争和移民经历的定性研究很少。在本研究中,我们描述了越南认知衰老项目(VIP)参与者的战争相关创伤和力量。方法:VIP是一项对548名居住在北加州65岁以上的越南裔美国人的纵向研究。在访问1期间,对参与者在越南和移民到美国的生活和经历进行了半结构化访谈。利用其中一个招募地点的数据,用越南语(N=43)转录了自我报告创伤总数最高的参与者的访谈,以便按照主题方法进行编码和分析。结果:参与者平均年龄73.2岁(SD=5.48)。大多数是男性(67.4%),并且至少有一次试图乘船逃离越南(67%)。两大主题:(1)逆境和苦难的经历,包括战争期间艰难的生活经历、战后监禁和艰苦的生活、乘船逃亡和难民营生活、目睹或听到他人在战争和逃亡期间的创伤和失去的经历;(2)个人毅力和感恩,包括毅力和耐力、个人应对和导航的技能,以及感知到的“运气和祝福”。讨论:本研究的结果揭示了各种创伤和力量的方面。这些发现有助于未来认知衰老的VIP研究,并为健康差异的研究和实践提供信息。
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引用次数: 0
Modifiable Risk Factors for Cognitive Decline in Community-Dwelling Older Adults Differ by Sex and APOE4. 社区老年人认知能力下降的可改变危险因素因性别和APOE4而异。
IF 3.2 2区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-04-07 DOI: 10.1093/geronb/gbaf005
Emilie T Reas, Humberto Parada, Jaclyn Bergstrom, Linda K McEvoy

Objectives: The extent to which lifestyle shapes trajectories of normal cognitive aging, and the factors with highest potential for mitigating cognitive decline, remain poorly characterized.

Methods: Participants of the Rancho Bernardo Study underwent demographic, health, and behavioral characterization at baseline, along with up to 7 cognitive assessments over a 27-year follow-up period. Factor analysis of 24 baseline risk variables identified 9 composite factors. Mixed effects models on data from 1,489 participants (aged 45-95 years at baseline) assessed prediction of cognitive change by baseline factor scores. Models were repeated stratified by sex and APOE4 status.

Results: Factors of hyperlipidemia and obesity; marriage and depression; occupation and education; and physical activity and subjective health best predicted rates of decline across multiple cognitive domains. Distinct risk profiles were identified for women and men, and for APOE4 carriers and non-carriers. Models of composite risk estimated that potential savings could amount to 7-9.5 years of preserved cognitive health span for low- versus high-risk profiles. Magnitudes of aggregate risk effects were greater among women across cognitive domains, and for APOE4 carriers for memory and verbal fluency.

Discussion: Multifactorial life-course approaches to manage cardiometabolic health and promote physical, cognitive, and social engagement may help to mitigate cognitive decline with age, with composite risk associated with up to a decade of preserved cognitive health span. Differences by sex and APOE4 in risk profiles and their potential for risk reduction, highlight the importance of developing personalized recommendations for multidomain approaches to cognitive health maintenance throughout the life-course.

目的:生活方式在多大程度上塑造了正常认知衰老的轨迹,以及最有可能减轻认知衰退的因素,目前还没有明确的特征。方法:Rancho Bernardo研究的参与者在基线时接受了人口统计学、健康和行为特征,并在27年的随访期间进行了多达7项认知评估。对24个基线风险变量进行因素分析,确定了9个复合因素。基于1489名参与者(基线年龄45-95岁)数据的混合效应模型评估了基线因子得分对认知变化的预测。按性别和APOE4状态对模型重复分层。结果:高脂血症与肥胖因素;婚姻与抑郁;职业与教育;体育活动和主观健康状况最能预测多个认知领域的衰退率。在女性和男性、APOE4携带者和非携带者中发现了不同的风险概况。综合风险模型估计,对于低风险和高风险人群,潜在的节省可能相当于保持7-9.5年的认知健康跨度。在认知领域,APOE4携带者在记忆力和语言流畅性方面的总体风险效应在女性中更大。讨论:多因素生命过程方法来管理心脏代谢健康,促进身体、认知和社会参与,可能有助于减轻随年龄增长的认知能力下降,复合风险与长达十年的认知健康期有关。性别和APOE4在风险概况及其降低风险的潜力方面的差异,突出了在整个生命过程中为多领域认知健康维持方法制定个性化建议的重要性。
{"title":"Modifiable Risk Factors for Cognitive Decline in Community-Dwelling Older Adults Differ by Sex and APOE4.","authors":"Emilie T Reas, Humberto Parada, Jaclyn Bergstrom, Linda K McEvoy","doi":"10.1093/geronb/gbaf005","DOIUrl":"10.1093/geronb/gbaf005","url":null,"abstract":"<p><strong>Objectives: </strong>The extent to which lifestyle shapes trajectories of normal cognitive aging, and the factors with highest potential for mitigating cognitive decline, remain poorly characterized.</p><p><strong>Methods: </strong>Participants of the Rancho Bernardo Study underwent demographic, health, and behavioral characterization at baseline, along with up to 7 cognitive assessments over a 27-year follow-up period. Factor analysis of 24 baseline risk variables identified 9 composite factors. Mixed effects models on data from 1,489 participants (aged 45-95 years at baseline) assessed prediction of cognitive change by baseline factor scores. Models were repeated stratified by sex and APOE4 status.</p><p><strong>Results: </strong>Factors of hyperlipidemia and obesity; marriage and depression; occupation and education; and physical activity and subjective health best predicted rates of decline across multiple cognitive domains. Distinct risk profiles were identified for women and men, and for APOE4 carriers and non-carriers. Models of composite risk estimated that potential savings could amount to 7-9.5 years of preserved cognitive health span for low- versus high-risk profiles. Magnitudes of aggregate risk effects were greater among women across cognitive domains, and for APOE4 carriers for memory and verbal fluency.</p><p><strong>Discussion: </strong>Multifactorial life-course approaches to manage cardiometabolic health and promote physical, cognitive, and social engagement may help to mitigate cognitive decline with age, with composite risk associated with up to a decade of preserved cognitive health span. Differences by sex and APOE4 in risk profiles and their potential for risk reduction, highlight the importance of developing personalized recommendations for multidomain approaches to cognitive health maintenance throughout the life-course.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11974396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Family Size Across the Life Course and Cognitive Decline in Older Mexican Adults. 墨西哥老年人生命历程中的家庭规模与认知能力下降。
IF 3.2 2区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-04-07 DOI: 10.1093/geronb/gbaf010
Joseph Saenz, Nekehia T Quashie, Xing Zhang

Objectives: A growing body of research has identified associations between family size and cognition in older adults. These studies largely focus on older adults' own fertility history instead of sibship size, defined as one's number of siblings. Sibship size may affect cognitive development during early childhood, creating differences that may persist into late life. Using a gendered life course framework, this study evaluates how family size across the life course (both sibship size and number of children) relates to cognitive aging among older Mexican adults.

Methods: Data come from the 2012, 2015, 2018, and 2021 waves of the Mexican Health and Aging Study (n = 14,872 adults age 50+). We use latent growth curve models to evaluate how family size (sibship size and fertility history) relates with levels of latent general cognitive ability and 9-year cognitive decline and variation across gender.

Results: Small sibship size related to higher levels of cognitive ability among men, but not women. This benefit was somewhat reduced when educational attainment was accounted for. Regarding fertility history, we observed an inverse U-shaped relationship with the level of cognitive ability, regardless of gender, that remained significant even after accounting for sibship size and other confounders. Neither family size measure predicted the rate of cognitive decline.

Discussion: This research broadens our understanding of family size and cognition associations in the context of Mexico's changing demographics that challenge the reliance on family support in late life and highlights potential gender differences.

目的:越来越多的研究已经确定了家庭规模与老年人认知能力之间的联系。这些研究主要关注老年人自己的生育史,而不是兄弟姐妹的数量,即一个人的兄弟姐妹数量。兄弟姐妹的大小可能会影响儿童早期的认知发展,造成的差异可能会持续到晚年。使用性别生命历程框架,本研究评估了整个生命历程中的家庭规模(兄弟姐妹规模和子女数量)与墨西哥老年人认知衰老的关系。方法:数据来自2012年、2015年、2018年和2021年的墨西哥健康与老龄化研究(n= 14872名50岁以上的成年人)。我们使用潜在增长曲线模型来评估家庭规模(兄弟姐妹规模和生育史)与潜在一般认知能力水平、九年认知能力下降和性别差异之间的关系。结果:兄弟姐妹的小与男性较高水平的认知能力有关,但与女性无关。如果把受教育程度考虑在内,这种好处就会有所减少。关于生育史,我们观察到与认知能力水平呈负u型关系,无论性别,即使在考虑了兄弟姐妹规模和其他混杂因素后,这一关系仍然显著。两种家庭规模的测量方法都无法预测认知能力下降的速度。讨论:本研究扩大了我们对墨西哥人口结构变化背景下家庭规模和认知关联的理解,这些变化挑战了人们晚年对家庭支持的依赖,并突出了潜在的性别差异。
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引用次数: 0
Distribution of Informal Caregiving for Older Adults Living With or At Risk of Cognitive Decline Within and Beyond Family in Rural South Africa. 南非农村地区家庭内外对患有或有认知能力下降风险的老年人的非正式照料分布情况。
IF 4.8 2区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-04-07 DOI: 10.1093/geronb/gbaf008
Sostina S Matina, Lenore Manderson, Michelle Brear, Farirai Rusere, F Xavier Gómez-Olivé, Kathleen Kahn, Guy Harling

Objectives: Aging populations will increasingly need care, much of this provided informally particularly in rural areas and in low and middle-income countries. In rural South Africa, formal support is severely limited, and adult children are frequently unavailable due to morbidity, early mortality, employment, and migration. We describe how care is shared within and between households.

Methods: We conducted quantitative interviews with 1,012 household members and nonhousehold caregivers of 106 older adults (age ≥54) living with or at risk of cognitive decline in rural Mpumalanga, South Africa. Using descriptive statistics and regression analysis, we described how care is shared, with particular attention to generational patterns of care.

Results: Spouses, the majority women, commonly considered themselves primary caregivers. informal care was spread among family, friends, and neighbors, most commonly by unemployed female relatives 1 or 2 generations younger than the recipient. A small number of paid caregivers, also mostly female, provided the most intensive care.

Discussion: Informal care for older adults was spread widely, predominantly from coresident family but with important contributions from others. Family commitment to care reflected shared history, reciprocal relationships, and easy access to care tasks within the household. A deeper understanding of how informal care for older adults is shared is essential for developing targeted interventions.

目标:老龄人口将越来越需要护理,其中大部分是非正式提供的,特别是在农村地区和低收入和中等收入国家。在南非农村,正式支助严重有限,由于发病、早亡、就业和移徙,成年子女往往无法获得。我们描述了如何在家庭内部和家庭之间分担照顾。方法:我们对南非姆普马兰加省农村地区106名患有或有认知能力下降风险的老年人(年龄≥54岁)的1,012名家庭成员和非家庭照顾者进行了定量访谈。使用描述性统计和回归分析,我们描述了如何共享护理,特别注意代际模式的护理。结果:配偶,大多数是女性,通常认为自己是主要的照顾者。非正式的照料在家庭、朋友和邻居之间传播,最常见的是由比接受者年轻一两代的失业女性亲属提供。少数付费的护理人员,也大多是女性,提供了最深入的护理。讨论:对老年人的非正式照顾广泛传播,主要来自共同居住的家庭,但也有其他人的重要贡献。家庭对护理的承诺反映了共同的历史、互惠的关系以及在家庭内容易获得护理任务。更深入地了解老年人的非正式护理是如何共享的,这对于制定有针对性的干预措施至关重要。
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引用次数: 0
Aberrant Structural-Functional Coupling of Large-Scale Brain Networks in Older Women With Subthreshold Depression. 阈下抑郁症老年妇女大尺度脑网络结构-功能耦合异常。
IF 4.8 2区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-04-07 DOI: 10.1093/geronb/gbaf013
Xueling Suo, Li Chen, Graham J Kemp, Dongmei Wu, Song Wang

Objectives: Subthreshold depression (SD) is common in the older population, more so in females than males, and can lead to serious physical and mental ill-health. However, the underlying neurobiology remains unclear. This study used multimodal magnetic resonance imaging (MRI) to investigate the topological organization and coupling of the structural and functional brain networks in older women with SD.

Methods: We constructed the structural network from diffusion MRI and the functional network from resting-state functional MRI in 50 older women with SD and 52 demographically matched older women healthy controls (HC). We used graph theory analysis to examine the topological properties of functional and structural networks, and structural-functional connectivity (SC-FC) coupling, and their potential relationship to depressive symptoms.

Results: Globally, compared with older women HC, the older women with SD showed lower local efficiency in the structural network but not the functional network. Locally, older women with SD showed altered convergent nodal metrics in the default mode, salience, and sensorimotor network regions in both structural and functional networks. Moreover, SC-FC coupling reduced in older women with SD compared to older women HC. These network metric alterations were correlated with depressive symptoms.

Discussion: Older women with SD showed alterations in both structural and functional networks, and in their coupling, which throw light on the role of large-scale brain networks in older female SD.

目的:阈下抑郁症(SD)在老年人群中很常见,女性多于男性,可导致严重的身心健康问题。然而,其潜在的神经生物学特性仍不清楚。本研究利用多模态磁共振成像(MRI)研究了患有SD的老年女性大脑结构和功能网络的拓扑组织和耦合:方法:我们从50名患有SD的老年女性和52名人口统计学上匹配的老年女性健康对照组(HC)的弥散核磁共振成像中构建了结构网络,从静息态功能核磁共振成像中构建了功能网络。我们使用图论分析法研究了功能和结构网络的拓扑特性、结构-功能连通性(SC-FC)耦合及其与抑郁症状的潜在关系:结果:从整体上看,与高龄女性相比,患有 SD 的高龄女性在结构网络中表现出较低的局部效率,而在功能网络中则没有。从局部来看,患有 SD 的老年女性在结构网络和功能网络中的默认模式、显著性和感觉运动网络区域的收敛结点指标都发生了改变。此外,与HC老年妇女相比,SD老年妇女的SC-FC耦合降低。这些网络指标的改变与抑郁症状相关:讨论:老年女性自闭症患者的结构和功能网络及其耦合都发生了改变,这揭示了大规模大脑网络在老年女性自闭症患者中的作用。
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引用次数: 0
Gendered Marital Power, Depression, and Cognition Among Older Adults in Mexico. 墨西哥老年人的婚姻权力、抑郁和认知。
IF 3.2 2区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-04-07 DOI: 10.1093/geronb/gbae193
Nekehia T Quashie, Joseph L Saenz, Connor Sheehan, Angelica Lopez

Objectives: As Mexico rapidly ages, population-level cognitive issues and Alzheimer's Disease and Related Dementia are projected to increase. Limited social welfare positions family members-especially spouses-as the main support resource. Although past research suggests marital power imbalances relate with increased depression among Mexican older adults, how marital power imbalance relates with cognition and gender differences therein remains understudied. Accordingly, we investigate how perceived marital power relates with cognitive ability with attention to depression and gender.

Methods: We use the 2012, 2015, and 2018 (n = 2,643 heterosexual dyads) waves of the Mexican Health and Aging Study and Actor Partner Interdependence Models (APIM). The APIM allows the cognitive function of each partner to be predicted by their own (actor effects) and partner's (partner effects) perceived marital power imbalance, evaluates gender differences, and the mediating role of depression.

Results: Own reports of lower baseline marital power were directly negatively associated with subsequent cognition only among husbands. Partners' baseline reports of marital power showed mixed direct associations with future cognition: husbands' higher marital power negatively related with wives' cognition, whereas wives' lower marital power positively related with husbands' cognition. Wives' marital power imbalance predicted higher depression in each partner, and both own and partner's depression related with lower cognition, regardless of gender, suggesting that wives' marital power imbalance affects cognition indirectly through depression.

Discussion: Our findings suggest that gendered marital power relations is a novel area for future research in the context of Mexico's aging population, enduring marriages, and entrenched patriarchal structures.

目标:随着墨西哥迅速老龄化,人口层面的认知问题和阿尔茨海默病及相关痴呆(AD/ADRD)预计将增加。有限的社会福利使得家庭成员——尤其是配偶——成为主要的支持资源。虽然过去的研究表明,婚姻权力失衡与墨西哥老年人抑郁症的增加有关,但婚姻权力失衡与认知和性别差异之间的关系仍未得到充分研究。因此,我们研究如何感知婚姻权力与认知能力与抑郁和性别的关系。方法:我们使用2012年、2015年和2018年(n = 2643对异性恋夫妇)墨西哥健康与老龄化研究(MHAS)和演员伴侣相互依赖模型(APIM)的波浪。APIM允许每个伴侣的认知功能通过他们自己(行动者效应)和伴侣(伴侣效应)感知的婚姻权力失衡来预测,评估性别差异,以及抑郁的中介作用。结果:只有在丈夫中,自己报告的较低基线婚姻权力与随后的认知直接负相关。伴侣对婚姻权力的基线报告显示了与未来认知的混合直接关联:丈夫较高的婚姻权力与妻子的认知负相关,而妻子较低的婚姻权力与丈夫的认知正相关。无论性别如何,妻子的婚姻权力失衡均预示着双方抑郁程度的升高,且双方的抑郁程度均与认知程度的降低相关,表明妻子的婚姻权力失衡通过抑郁间接影响认知。讨论:我们的研究结果表明,在墨西哥人口老龄化、婚姻持久和父权结构根深蒂固的背景下,性别婚姻权力关系是未来研究的一个新领域。
{"title":"Gendered Marital Power, Depression, and Cognition Among Older Adults in Mexico.","authors":"Nekehia T Quashie, Joseph L Saenz, Connor Sheehan, Angelica Lopez","doi":"10.1093/geronb/gbae193","DOIUrl":"10.1093/geronb/gbae193","url":null,"abstract":"<p><strong>Objectives: </strong>As Mexico rapidly ages, population-level cognitive issues and Alzheimer's Disease and Related Dementia are projected to increase. Limited social welfare positions family members-especially spouses-as the main support resource. Although past research suggests marital power imbalances relate with increased depression among Mexican older adults, how marital power imbalance relates with cognition and gender differences therein remains understudied. Accordingly, we investigate how perceived marital power relates with cognitive ability with attention to depression and gender.</p><p><strong>Methods: </strong>We use the 2012, 2015, and 2018 (n = 2,643 heterosexual dyads) waves of the Mexican Health and Aging Study and Actor Partner Interdependence Models (APIM). The APIM allows the cognitive function of each partner to be predicted by their own (actor effects) and partner's (partner effects) perceived marital power imbalance, evaluates gender differences, and the mediating role of depression.</p><p><strong>Results: </strong>Own reports of lower baseline marital power were directly negatively associated with subsequent cognition only among husbands. Partners' baseline reports of marital power showed mixed direct associations with future cognition: husbands' higher marital power negatively related with wives' cognition, whereas wives' lower marital power positively related with husbands' cognition. Wives' marital power imbalance predicted higher depression in each partner, and both own and partner's depression related with lower cognition, regardless of gender, suggesting that wives' marital power imbalance affects cognition indirectly through depression.</p><p><strong>Discussion: </strong>Our findings suggest that gendered marital power relations is a novel area for future research in the context of Mexico's aging population, enduring marriages, and entrenched patriarchal structures.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12019229/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Parent-Adult Child Relationships and Repartnering After Gray Divorce. 父母-成人-子女关系和灰色离婚后的再合作。
IF 3.2 2区 医学 Q1 GERIATRICS & GERONTOLOGY Pub Date : 2025-04-07 DOI: 10.1093/geronb/gbaf011
Susan L Brown, I-Fen Lin, Francesca A Marino, Kagan A Mellencamp

Objectives: The rise in gray divorce has catalyzed repartnering in later life. However, the antecedents of older adult repartnering remain poorly understood, particularly the potential role of adult children. A form of ambiguous loss, marital disruption often leads to family boundary ambiguity, thereby weakening family ties. We investigated whether co-residence and proximity of, frequent contact with, and downward transfers to adult children were negatively associated with repartnering after gray divorce.

Methods: Data from the 1998 to 2018 Health and Retirement Study were used to estimate discrete-time event history models using logistic regression to predict repartnering after gray divorce among parents of adult children (N = 1,359).

Results: As expected, adult child co-residence as well as having a child who lived nearby and had frequent contact diminished the likelihood of repartnering. Parents whose children either did not live nearby or were nearby but did not have frequent contact were more likely to repartner than those with children nearby and in frequent contact or co-residing, signaling that both proximity and frequency of contact are related to repartnering. Additionally, the provision of financial support to adult children was associated with a lower risk of repartnering.

Discussion: Relationships with adult children shape parental repartnering behaviors. Echoing the concept of boundary ambiguity, our findings indicate that stronger family ties, as signaled by child co-residence or proximity and frequent contact as well as economic provision, tend to deter repartnering. These findings also indicate that absent strong family ties, older adults are more likely to form a new union.

目的:“灰色离婚”的增多促使人们在晚年再婚。然而,人们对老年人再婚的起因仍然知之甚少,尤其是对成年子女的潜在作用。一种形式的模糊损失,婚姻破裂往往导致家庭边界模糊,从而削弱家庭关系。我们调查了共同居住和接近、频繁接触以及向下转移到成年子女是否与灰色离婚后的再婚负相关。方法:使用1998-2018年健康与退休研究的数据,使用logistic回归估计离散时间事件历史模型,以预测成年子女父母灰色离婚后的再婚(N = 1359)。结果:正如预期的那样,成年子女共同居住以及有一个住在附近并经常接触的孩子降低了再婚的可能性。孩子不住在附近或在附近但不经常联系的父母比那些孩子在附近且经常联系或共同居住的父母更有可能重新合作,这表明距离和接触频率都与重新合作有关。此外,为成年子女提供经济支持与较低的再婚风险有关。讨论:与成年子女的关系塑造了父母的再伴侣行为。与边界模糊的概念相呼应,我们的研究结果表明,更强的家庭关系,如儿童共同居住或邻近、频繁接触以及经济条件所表明的,往往会阻止再婚。这些发现还表明,如果没有牢固的家庭关系,老年人更有可能组建新的联盟。
{"title":"Parent-Adult Child Relationships and Repartnering After Gray Divorce.","authors":"Susan L Brown, I-Fen Lin, Francesca A Marino, Kagan A Mellencamp","doi":"10.1093/geronb/gbaf011","DOIUrl":"10.1093/geronb/gbaf011","url":null,"abstract":"<p><strong>Objectives: </strong>The rise in gray divorce has catalyzed repartnering in later life. However, the antecedents of older adult repartnering remain poorly understood, particularly the potential role of adult children. A form of ambiguous loss, marital disruption often leads to family boundary ambiguity, thereby weakening family ties. We investigated whether co-residence and proximity of, frequent contact with, and downward transfers to adult children were negatively associated with repartnering after gray divorce.</p><p><strong>Methods: </strong>Data from the 1998 to 2018 Health and Retirement Study were used to estimate discrete-time event history models using logistic regression to predict repartnering after gray divorce among parents of adult children (N = 1,359).</p><p><strong>Results: </strong>As expected, adult child co-residence as well as having a child who lived nearby and had frequent contact diminished the likelihood of repartnering. Parents whose children either did not live nearby or were nearby but did not have frequent contact were more likely to repartner than those with children nearby and in frequent contact or co-residing, signaling that both proximity and frequency of contact are related to repartnering. Additionally, the provision of financial support to adult children was associated with a lower risk of repartnering.</p><p><strong>Discussion: </strong>Relationships with adult children shape parental repartnering behaviors. Echoing the concept of boundary ambiguity, our findings indicate that stronger family ties, as signaled by child co-residence or proximity and frequent contact as well as economic provision, tend to deter repartnering. These findings also indicate that absent strong family ties, older adults are more likely to form a new union.</p>","PeriodicalId":56111,"journal":{"name":"Journals of Gerontology Series B-Psychological Sciences and Social Sciences","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11974390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journals of Gerontology Series B-Psychological Sciences and Social Sciences
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