Yi-Wei Wu, Gabriel Chan, Ivan Kuang Hsin Huang, Justin Kwan, Gavin Hock Tai Lim, Lawrence Han Hwee Quek, Uei Pua
This article demonstrates the technique of using a coaxial guiding needle to perform combined percutaneous biopsy and microwave ablation via a single tract. From May 2019 to July 2020, 14 patients underwent combined biopsy and microwave ablation by using a coaxial guiding cannula. Tumors were in the kidney of six patients (43%), the liver of six patients (43%), and the lung in two patients (14%). The diagnostic yield of biopsy was 86% (12/14). Ablation technical success rate was 100%. In conclusion, using a coaxial guiding needle in microwave ablation and biopsy is safe and effective.
{"title":"Combined Biopsy and Imaging-Guided Microwave Ablation by Using a Coaxial Guiding Needle.","authors":"Yi-Wei Wu, Gabriel Chan, Ivan Kuang Hsin Huang, Justin Kwan, Gavin Hock Tai Lim, Lawrence Han Hwee Quek, Uei Pua","doi":"10.5334/jbsr.2345","DOIUrl":"https://doi.org/10.5334/jbsr.2345","url":null,"abstract":"<p><p>This article demonstrates the technique of using a coaxial guiding needle to perform combined percutaneous biopsy and microwave ablation via a single tract. From May 2019 to July 2020, 14 patients underwent combined biopsy and microwave ablation by using a coaxial guiding cannula. Tumors were in the kidney of six patients (43%), the liver of six patients (43%), and the lung in two patients (14%). The diagnostic yield of biopsy was 86% (12/14). Ablation technical success rate was 100%. In conclusion, using a coaxial guiding needle in microwave ablation and biopsy is safe and effective.</p>","PeriodicalId":56282,"journal":{"name":"Journal of the Belgian Society of Radiology","volume":"105 1","pages":"25"},"PeriodicalIF":2.0,"publicationDate":"2021-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103851/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38979701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jesper Dierickx, Filip Vanhoenacker, Virginie Merckaert
Teaching Point: Snowball-like and icicle-like lesions in the corpus callosum suggest Susac Syndrome.
教学点:胼胝体雪球样和冰柱样病变提示Susac综合征。
{"title":"Snowballs and Icicles in Susac's Syndrome.","authors":"Jesper Dierickx, Filip Vanhoenacker, Virginie Merckaert","doi":"10.5334/jbsr.2441","DOIUrl":"https://doi.org/10.5334/jbsr.2441","url":null,"abstract":"<p><p><b>Teaching Point:</b> Snowball-like and icicle-like lesions in the corpus callosum suggest Susac Syndrome.</p>","PeriodicalId":56282,"journal":{"name":"Journal of the Belgian Society of Radiology","volume":"105 1","pages":"24"},"PeriodicalIF":2.0,"publicationDate":"2021-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064299/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38890757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Subgaleal lipoma is a benign tumor of adipose tissue. It should be suspected when a semi-spherical avascular mass with well-defined margins, iso- or hyperechoic in most cases, with thin internal echogenic lines parallel to the long axis of the tumor, is observed between the galea aponeurosis and periosteum of the cranial bone. We report a series of cases of three patients who underwent surgical lesion excision and whose histopathological examination findings confirmed the diagnosis of lipoma.
Main teaching point: The presence of long continuous echogenic lines within a lens-shaped soft tissue mass located beneath the galea aponeurosis may suggest the diagnosis of subgaleal lipoma.
{"title":"Subgaleal Lipoma: Imaging Findings.","authors":"Mihaela-Magdalena Vlad, Michaël Dupont, Françoise Kayser","doi":"10.5334/jbsr.2372","DOIUrl":"https://doi.org/10.5334/jbsr.2372","url":null,"abstract":"<p><p>Subgaleal lipoma is a benign tumor of adipose tissue. It should be suspected when a semi-spherical avascular mass with well-defined margins, iso- or hyperechoic in most cases, with thin internal echogenic lines parallel to the long axis of the tumor, is observed between the galea aponeurosis and periosteum of the cranial bone. We report a series of cases of three patients who underwent surgical lesion excision and whose histopathological examination findings confirmed the diagnosis of lipoma.</p><p><strong>Main teaching point: </strong>The presence of long continuous echogenic lines within a lens-shaped soft tissue mass located beneath the galea aponeurosis may suggest the diagnosis of subgaleal lipoma.</p>","PeriodicalId":56282,"journal":{"name":"Journal of the Belgian Society of Radiology","volume":"105 1","pages":"23"},"PeriodicalIF":2.0,"publicationDate":"2021-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064296/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38890756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Teaching point: Myelopathy may occur following nitrous oxide (N2O) misuse, even if vitamin B12-levels are normal. The typical appearance on magnetic resonance imaging (MRI), is an inverted V-shaped T2-weighted hypersignal in the dorsal columns of the cervicothoracic spinal cord.
{"title":"MRI of Nitrous Oxide-Related Subacute Cervical Myelopathy.","authors":"Leo Vael, Van Walleghem Phyllis, Özkan Özsarlak","doi":"10.5334/jbsr.2347","DOIUrl":"https://doi.org/10.5334/jbsr.2347","url":null,"abstract":"<p><p><b>Teaching point:</b> Myelopathy may occur following nitrous oxide (N<sub>2</sub>O) misuse, even if vitamin B12-levels are normal. The typical appearance on magnetic resonance imaging (MRI), is an inverted V-shaped T2-weighted hypersignal in the dorsal columns of the cervicothoracic spinal cord.</p>","PeriodicalId":56282,"journal":{"name":"Journal of the Belgian Society of Radiology","volume":"105 1","pages":"22"},"PeriodicalIF":2.0,"publicationDate":"2021-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38819608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stefaan Van Hoe, Olivier Bladt, Kris Van Der Steen, Herman Van den Eynde
Sclerotic lesions of the jaw are uncommon but may be clinically relevant. In this pictorial review, the most common sclerotic lesions are discussed. Three categories of lesions are distinguished; odontogenic sclerotic lesions, non-odontogenic sclerotic lesions, and mixed lytic-sclerotic lesions. In each group, non-neoplastic conditions are discussed first, followed by benign and malignant neoplasms. For each disease a brief overview is given, including histological features, epidemiology, symptoms, typical location, imaging features, and treatment. This review emphasizes which basic observations are essential to the evaluation of sclerotic jaw lesions and what elements have to be taken into account to create a proper differential diagnosis.
{"title":"Sclerotic Lesions of the Jaw: A Pictorial Review.","authors":"Stefaan Van Hoe, Olivier Bladt, Kris Van Der Steen, Herman Van den Eynde","doi":"10.5334/jbsr.2208","DOIUrl":"https://doi.org/10.5334/jbsr.2208","url":null,"abstract":"<p><p>Sclerotic lesions of the jaw are uncommon but may be clinically relevant. In this pictorial review, the most common sclerotic lesions are discussed. Three categories of lesions are distinguished; odontogenic sclerotic lesions, non-odontogenic sclerotic lesions, and mixed lytic-sclerotic lesions. In each group, non-neoplastic conditions are discussed first, followed by benign and malignant neoplasms. For each disease a brief overview is given, including histological features, epidemiology, symptoms, typical location, imaging features, and treatment. This review emphasizes which basic observations are essential to the evaluation of sclerotic jaw lesions and what elements have to be taken into account to create a proper differential diagnosis.</p>","PeriodicalId":56282,"journal":{"name":"Journal of the Belgian Society of Radiology","volume":"105 1","pages":"21"},"PeriodicalIF":2.0,"publicationDate":"2021-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38819609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evelien Claesen, Steven Van den Berge, Enrique Havinga
Teaching point: Extrahepatic portosystemic shunt is a rare congenital condition, associated with other congenital anomalies, for which prompt radiological diagnosis and treatment are important to prevent complications.
{"title":"Abernethy Malformation Type 1b.","authors":"Evelien Claesen, Steven Van den Berge, Enrique Havinga","doi":"10.5334/jbsr.2431","DOIUrl":"https://doi.org/10.5334/jbsr.2431","url":null,"abstract":"<p><p><b>Teaching point:</b> Extrahepatic portosystemic shunt is a rare congenital condition, associated with other congenital anomalies, for which prompt radiological diagnosis and treatment are important to prevent complications.</p>","PeriodicalId":56282,"journal":{"name":"Journal of the Belgian Society of Radiology","volume":"105 1","pages":"20"},"PeriodicalIF":2.0,"publicationDate":"2021-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38819607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Johannes Devos, Lawrence Bonne, Sandra Cornelissen, Walter Coudyzer, Wim Laleman, Chris Verslype, Willem-Jan Metsemakers, Geert Maleux
Purpose: To assess the safety and efficacy of main splenic artery embolization. To assess the potential difference post-embolization of the residual splenic volume in patients embolized for trauma versus those embolized for (pseudo)aneurysms.
Materials and methods: A retrospective analysis was performed on a cohort of 65 patients (36 males) who underwent pre- and post-embolization computed tomography. Patients' demographics, pre- and post-interventional medical and radiological data were gathered. Splenic volume calculations were semi-automatically performed via a workstation. Patients with splenic aneurysms or pseudoaneurysms of the main splenic artery (group 1) were compared to those with splenic rupture (group 2) using Wilcoxon rank tests.
Results: The main indications for splenic artery embolization were splenic rupture (n = 22; 34%) and splenic pseudoaneurysm (n = 19; 29%). The technical success rate was n = 63; 97%. The procedure-related complication rate was n = 7; 11%, including abscess formation (n = 5; 8%), re-bleeding (n = 1; 1.5 %) and pseudoaneurysm re-opening (n = 1; 1.5%). The overall 30-day mortality was n = 7; 11%.Median follow-up for groups 1 and 2 was 1163 days (61-3946 days) and 702 days (43-2095 days) respectively. When processable (n = 23), the splenic volume in group 1 (n = 7) was 311 cm3 and 257 cm3 (p = 0.1591) before and after embolization respectively, and in group 2 (n = 16) it was 261 cm3 and 215 cm3 (p = 0.4688), respectively.
Conclusions: Main splenic artery embolization is efficacious, with low procedure-related complication and 30-day mortality rates. No significant differences in residual post-embolization splenic volume were found between patients treated for splenic rupture versus those treated for splenic arterial (pseudo)aneurysm.
{"title":"Residual Splenic Volume after Main Splenic Artery Embolization is Independent of the Underlying Disease.","authors":"Johannes Devos, Lawrence Bonne, Sandra Cornelissen, Walter Coudyzer, Wim Laleman, Chris Verslype, Willem-Jan Metsemakers, Geert Maleux","doi":"10.5334/jbsr.2068","DOIUrl":"https://doi.org/10.5334/jbsr.2068","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the safety and efficacy of main splenic artery embolization. To assess the potential difference post-embolization of the residual splenic volume in patients embolized for trauma versus those embolized for (pseudo)aneurysms.</p><p><strong>Materials and methods: </strong>A retrospective analysis was performed on a cohort of 65 patients (36 males) who underwent pre- and post-embolization computed tomography. Patients' demographics, pre- and post-interventional medical and radiological data were gathered. Splenic volume calculations were semi-automatically performed via a workstation. Patients with splenic aneurysms or pseudoaneurysms of the main splenic artery (group 1) were compared to those with splenic rupture (group 2) using Wilcoxon rank tests.</p><p><strong>Results: </strong>The main indications for splenic artery embolization were splenic rupture (n = 22; 34%) and splenic pseudoaneurysm (n = 19; 29%). The technical success rate was n = 63; 97%. The procedure-related complication rate was n = 7; 11%, including abscess formation (n = 5; 8%), re-bleeding (n = 1; 1.5 %) and pseudoaneurysm re-opening (n = 1; 1.5%). The overall 30-day mortality was n = 7; 11%.Median follow-up for groups 1 and 2 was 1163 days (61-3946 days) and 702 days (43-2095 days) respectively. When processable (n = 23), the splenic volume in group 1 (n = 7) was 311 cm<sup>3</sup> and 257 cm<sup>3</sup> (p = 0.1591) before and after embolization respectively, and in group 2 (n = 16) it was 261 cm<sup>3</sup> and 215 cm<sup>3</sup> (p = 0.4688), respectively.</p><p><strong>Conclusions: </strong>Main splenic artery embolization is efficacious, with low procedure-related complication and 30-day mortality rates. No significant differences in residual post-embolization splenic volume were found between patients treated for splenic rupture versus those treated for splenic arterial (pseudo)aneurysm.</p>","PeriodicalId":56282,"journal":{"name":"Journal of the Belgian Society of Radiology","volume":"105 1","pages":"19"},"PeriodicalIF":2.0,"publicationDate":"2021-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38819606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charlotte Biebau, Adriana Dubbeldam, Lesley Cockmartin, Walter Coudyze, Johan Coolen, Johny Verschakelen, Walter De Wever
Objectives: Fast diagnosis of Coronavirus Disease 2019 (COVID-19), and the detection of high-risk patients are crucial but challenging in the pandemic outbreak. The aim of this study was to evaluate if deep learning-based software correlates well with the generally accepted visual-based scoring for quantification of the lung injury to help radiologist in triage and monitoring of COVID-19 patients.
Materials and methods: In this retrospective study, the lobar analysis of lung opacities (% opacities) by means of a prototype deep learning artificial intelligence (AI)-based software was compared to visual scoring. The visual scoring system used five categories (0: 0%, 1: 0-5%, 2: 5-25%, 3: 25-50%, 4: 50-75% and 5: >75% involvement). The total visual lung injury was obtained by the sum of the estimated grade of involvement of each lobe and divided by five.
Results: The dataset consisted of 182 consecutive confirmed COVID-19 positive patients with a median age of 65 ± 16 years, including 110 (60%) men and 72 (40%) women. There was a correlation coefficient of 0.89 (p < 0.001) between the visual and the AI-based estimates of the severity of lung injury.
Conclusion: The study indicates a very good correlation between the visual scoring and AI-based estimates of lung injury in COVID-19.
{"title":"Comparing Visual Scoring of Lung Injury with a Quantifying AI-Based Scoring in Patients with COVID-19.","authors":"Charlotte Biebau, Adriana Dubbeldam, Lesley Cockmartin, Walter Coudyze, Johan Coolen, Johny Verschakelen, Walter De Wever","doi":"10.5334/jbsr.2330","DOIUrl":"10.5334/jbsr.2330","url":null,"abstract":"<p><strong>Objectives: </strong>Fast diagnosis of Coronavirus Disease 2019 (COVID-19), and the detection of high-risk patients are crucial but challenging in the pandemic outbreak. The aim of this study was to evaluate if deep learning-based software correlates well with the generally accepted visual-based scoring for quantification of the lung injury to help radiologist in triage and monitoring of COVID-19 patients.</p><p><strong>Materials and methods: </strong>In this retrospective study, the lobar analysis of lung opacities (% opacities) by means of a prototype deep learning artificial intelligence (AI)-based software was compared to visual scoring. The visual scoring system used five categories (0: 0%, 1: 0-5%, 2: 5-25%, 3: 25-50%, 4: 50-75% and 5: >75% involvement). The total visual lung injury was obtained by the sum of the estimated grade of involvement of each lobe and divided by five.</p><p><strong>Results: </strong>The dataset consisted of 182 consecutive confirmed COVID-19 positive patients with a median age of 65 ± 16 years, including 110 (60%) men and 72 (40%) women. There was a correlation coefficient of 0.89 (<i>p</i> < 0.001) between the visual and the AI-based estimates of the severity of lung injury.</p><p><strong>Conclusion: </strong>The study indicates a very good correlation between the visual scoring and AI-based estimates of lung injury in COVID-19.</p>","PeriodicalId":56282,"journal":{"name":"Journal of the Belgian Society of Radiology","volume":"105 1","pages":"16"},"PeriodicalIF":2.0,"publicationDate":"2021-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38806920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frederik Bosmans, Sofie Dekeyzer, Filip Vanhoenacker
Teaching point: Granular cell tumors are rare soft tissue tumors that may occur in the breast. While almost always benign, they may mimic a malignant tumor both clinically and on imaging.
{"title":"Granular Cell Tumor: A Mimicker of Breast Carcinoma.","authors":"Frederik Bosmans, Sofie Dekeyzer, Filip Vanhoenacker","doi":"10.5334/jbsr.2409","DOIUrl":"https://doi.org/10.5334/jbsr.2409","url":null,"abstract":"<p><p><b>Teaching point:</b> Granular cell tumors are rare soft tissue tumors that may occur in the breast. While almost always benign, they may mimic a malignant tumor both clinically and on imaging.</p>","PeriodicalId":56282,"journal":{"name":"Journal of the Belgian Society of Radiology","volume":"105 1","pages":"18"},"PeriodicalIF":2.0,"publicationDate":"2021-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38819605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brecht Van Berkel, Jan Vandevenne, Kristof Coursier, Vincent Alberts, Jan Van Offenwert, Jan Verduyckt, Martijn Grieten, Wim Siemons, Geert Verswijvel
Objectives: Both Reporting and Data System (CO-RADS) and CT-involvement scores (CTIS) have been proposed for evaluation of COVID-19 on chest CT. The purpose of this single-center, retrospective study was to evaluate both scoring systems to diagnose COVID-19 infection in a high-prevalence area.
Materials and methods: Chest CT datasets (n = 200) and available reverse transcription polymerase chain reaction (RT-PCR) on nasopharyngeal swab were included. CT scans were assigned to four 'imaging groups' after scoring for both CO-RADS and CTIS. Diagnostic accuracy of chest CT was calculated respectively using RT-PCR and clinical diagnosis as gold standards: False-negatives and false-positives of chest CT regarding RT-PCR were studied in more depth using the medical files.
Results: The 'imaging group' including CO-RADS 4/5 scores reached the highest diagnostic values for COVID-19 considering either the initial RT-PCR or the final clinical diagnosis as the standard of reference: accuracies of 172/200 (86%) to 181/200 (90.5%), sensitivities of 60/80 (88.2%) to 70/79 (88.6%), specificities of 112/132 (84.9%) to 111/121 (91.7%), negative predictive values (NPV) of 112/120 (93.3%) to 111/120 (92.5%), respectively. False-negative CTs regarding RT-PCR were mainly explained by imaging very early in the disease course (5 out of 8 cases) or COVID-19 infection with no/minor respiratory symptoms (3 out of 8 cases).
Conclusion: Assessing chest CT using CO-RADS is a valuable diagnostic approach for COVID-19 infection in a high-prevalence area, with a higher accuracy than CTIS.
{"title":"Chest CT Diagnosis of COVID-19: Accuracy using CO-RADS and CT-Involvement Scoring.","authors":"Brecht Van Berkel, Jan Vandevenne, Kristof Coursier, Vincent Alberts, Jan Van Offenwert, Jan Verduyckt, Martijn Grieten, Wim Siemons, Geert Verswijvel","doi":"10.5334/jbsr.2342","DOIUrl":"https://doi.org/10.5334/jbsr.2342","url":null,"abstract":"<p><strong>Objectives: </strong>Both Reporting and Data System (CO-RADS) and CT-involvement scores (CTIS) have been proposed for evaluation of COVID-19 on chest CT. The purpose of this single-center, retrospective study was to evaluate both scoring systems to diagnose COVID-19 infection in a high-prevalence area.</p><p><strong>Materials and methods: </strong>Chest CT datasets (n = 200) and available reverse transcription polymerase chain reaction (RT-PCR) on nasopharyngeal swab were included. CT scans were assigned to four 'imaging groups' after scoring for both CO-RADS and CTIS. Diagnostic accuracy of chest CT was calculated respectively using RT-PCR and clinical diagnosis as gold standards: False-negatives and false-positives of chest CT regarding RT-PCR were studied in more depth using the medical files.</p><p><strong>Results: </strong>The 'imaging group' including CO-RADS 4/5 scores reached the highest diagnostic values for COVID-19 considering either the initial RT-PCR or the final clinical diagnosis as the standard of reference: accuracies of 172/200 (86%) to 181/200 (90.5%), sensitivities of 60/80 (88.2%) to 70/79 (88.6%), specificities of 112/132 (84.9%) to 111/121 (91.7%), negative predictive values (NPV) of 112/120 (93.3%) to 111/120 (92.5%), respectively. False-negative CTs regarding RT-PCR were mainly explained by imaging very early in the disease course (5 out of 8 cases) or COVID-19 infection with no/minor respiratory symptoms (3 out of 8 cases).</p><p><strong>Conclusion: </strong>Assessing chest CT using CO-RADS is a valuable diagnostic approach for COVID-19 infection in a high-prevalence area, with a higher accuracy than CTIS.</p>","PeriodicalId":56282,"journal":{"name":"Journal of the Belgian Society of Radiology","volume":"105 1","pages":"17"},"PeriodicalIF":2.0,"publicationDate":"2021-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8034407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38819604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}