Xinyi Shen, Yingying Yu, Junyi Chen, Jie Shen, Jinming Zhang, Fu Lee Wang, J. Min
{"title":"靶向铁死亡防治脏器损伤及衰老相关疾病的转化医学研究","authors":"Xinyi Shen, Yingying Yu, Junyi Chen, Jie Shen, Jinming Zhang, Fu Lee Wang, J. Min","doi":"10.1360/ssv-2022-0241","DOIUrl":"https://doi.org/10.1360/ssv-2022-0241","url":null,"abstract":"","PeriodicalId":61900,"journal":{"name":"中国科学(生命科学)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42879688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R-loops are three-stranded chromatin structures composed of a single-stranded DNA and an RNA:DNA hybrid with important biological functions in numerous organisms. Numbers of R-loop regulators have been found to affect genomic events, such as transcription, replication, DNA damage, and repair, through modulating R-loop homeostasis. Over the last few years, with the development of R-loop detection methods, an increasing number of R-loop biological functions are being discovered. In this review, we provide an overview of R-loop detection methods and focus on the research progresses of R-loop functions in plants.
{"title":"Recent progresses on R-loop biology: from detection methods to biological functions","authors":"Jincong Zhou, Wenjie Wang, Qianwen Sun","doi":"10.1360/ssv-2021-0422","DOIUrl":"https://doi.org/10.1360/ssv-2021-0422","url":null,"abstract":"R-loops are three-stranded chromatin structures composed of a single-stranded DNA and an RNA:DNA hybrid with important biological functions in numerous organisms. Numbers of R-loop regulators have been found to affect genomic events, such as transcription, replication, DNA damage, and repair, through modulating R-loop homeostasis. Over the last few years, with the development of R-loop detection methods, an increasing number of R-loop biological functions are being discovered. In this review, we provide an overview of R-loop detection methods and focus on the research progresses of R-loop functions in plants.","PeriodicalId":61900,"journal":{"name":"中国科学(生命科学)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47352734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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