Pub Date : 2024-03-01DOI: 10.1016/j.cjprs.2024.02.002
Mengyuan Jiang , Haizhong Huo , Lu Zhang
Background
Autologous costal grafts are used universally in clinical practice for rhinoplasty and reconstruction. However, surgeons worldwide have not agreed on the details of graft harvesting, including rib selection, side preference, operation mode, cutting methods, and handling of the periosteum and perichondrium. This study aimed to provide an overview of the novel techniques used for auto-rib harvesting in rhinoplasty within the past 5 years and identify potential avenues for future research.
Methods
We searched for related articles in PubMed, Embase, and Web of Science from 2019 to 2023, summarized crucial but controversial steps in recent practice, and analyzed their theoretical basis and clinical feasibility.
Results
Auto-rib and cartilage open harvest is still mainstream in rhinoplasty and reconstruction, with the 5th to 8th ribs and cartilage being the most used. The laparoscopic harvest is gaining attention, being second only to the open harvest, with the 9th/10th ribs and cartilages being particularly convenient. The clinical applications of full-cut and split-cut methods differ in their advantages. Except for some special reasons, almost all studies tended to preserve the periosteum and perichondrium in situ, and few surgeons chose to harvest the grafts on the left side.
Conclusion
Multiple techniques have emerged, requiring surgeons to balance the benefits and risks of various strategies at each step. New theories and techniques should be fully tested promptly and in clinical practice before wide application. Overall, a professional consensus is needed for better directivity, precision, and stability in clinical practice.
背景自体肋骨移植物被普遍用于鼻整形和鼻重建的临床实践中。然而,世界各地的外科医生对移植物采集的细节,包括肋骨的选择、偏好的一侧、操作模式、切割方法以及骨膜和软骨膜的处理等,尚未达成一致意见。本研究旨在概述过去 5 年中用于鼻整形术中自体肋骨采集的新技术,并确定未来研究的潜在途径。方法我们在 PubMed、Embase 和 Web of Science 中检索了 2019 年至 2023 年的相关文章,总结了近期实践中关键但有争议的步骤,并分析了其理论基础和临床可行性。结果自体肋骨和软骨开放式采集仍是鼻整形和重建的主流,其中第 5 至第 8 根肋骨和软骨使用最多。腹腔镜取材越来越受到重视,仅次于开放式取材,其中第 9/10 肋骨和软骨的取材尤为方便。全切法和分切法的临床应用优势各不相同。除一些特殊原因外,几乎所有的研究都倾向于原位保留骨膜和软骨周围,很少有外科医生选择在左侧采集移植物。新理论和新技术在广泛应用之前,应及时在临床实践中进行充分检验。总之,要想在临床实践中获得更好的指导性、精确性和稳定性,需要达成专业共识。
{"title":"Current practice in autologous rib and costal-cartilage harvest for rhinoplasty: A systematic review","authors":"Mengyuan Jiang , Haizhong Huo , Lu Zhang","doi":"10.1016/j.cjprs.2024.02.002","DOIUrl":"10.1016/j.cjprs.2024.02.002","url":null,"abstract":"<div><h3>Background</h3><p>Autologous costal grafts are used universally in clinical practice for rhinoplasty and reconstruction. However, surgeons worldwide have not agreed on the details of graft harvesting, including rib selection, side preference, operation mode, cutting methods, and handling of the periosteum and perichondrium. This study aimed to provide an overview of the novel techniques used for auto-rib harvesting in rhinoplasty within the past 5 years and identify potential avenues for future research.</p></div><div><h3>Methods</h3><p>We searched for related articles in PubMed, Embase, and Web of Science from 2019 to 2023, summarized crucial but controversial steps in recent practice, and analyzed their theoretical basis and clinical feasibility.</p></div><div><h3>Results</h3><p>Auto-rib and cartilage open harvest is still mainstream in rhinoplasty and reconstruction, with the 5th to 8th ribs and cartilage being the most used. The laparoscopic harvest is gaining attention, being second only to the open harvest, with the 9th/10th ribs and cartilages being particularly convenient. The clinical applications of full-cut and split-cut methods differ in their advantages. Except for some special reasons, almost all studies tended to preserve the periosteum and perichondrium <em>in situ</em>, and few surgeons chose to harvest the grafts on the left side.</p></div><div><h3>Conclusion</h3><p>Multiple techniques have emerged, requiring surgeons to balance the benefits and risks of various strategies at each step. New theories and techniques should be fully tested promptly and in clinical practice before wide application. Overall, a professional consensus is needed for better directivity, precision, and stability in clinical practice.</p></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"6 1","pages":"Pages 41-48"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S209669112400013X/pdfft?md5=13332668ad1380b51a73e4ebe3788354&pid=1-s2.0-S209669112400013X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140269230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-01DOI: 10.1016/j.cjprs.2023.10.001
Zizhen Guo, Lingling Ge, Yuehua Li, Yihui Gu, Wei Wang, Chengjiang Wei, Bin Gu, Qingfeng Li, Zhichao Wang
Melanocytic nevus is mainly treated by complete or partial removal. However, predicting the risk of malignant transformation of melanocytic nevi and which treatment patients should receive, surgical or non-surgical management, to gain the best results and aesthetic outcomes is controversial. Global literature on melanocytic nevus treatment, published between 1997 and 2022, was scanned using the Web of Science Core Collection database. Microsoft Office Excel, CiteSpace V, VOSviewer, Scimago Graphica, Bibliometrix, and Biblioshiny packages in R were used for the bibliometric analysis to summarize the leading countries, institutions, professors, and research trends in this field. This study included 1 723 articles. Publications and citations exhibited positive trends over the past 20 years. The United States had the most productive organizations and publications in the comprehensive worldwide cooperation network, and China was recently one of the most active major participants. Professor Giovanni Pellacani, whose H-index, G-index, and M-index ranked first in this field, founded a virtual biopsy using reflectance confocal microscopy. In addition, Krengel and Kinsler contributed significantly to diagnosing and treating melanocytic nevi. The top 25 keywords in recent years were mostly about the mechanisms and risk factors for the malignant transformation of nevi. The future trend for melanocytic nevi treatment is to specify genotype-phenotype and genotype-outcome correlations, choose proper therapy to reduce the risk of malignant transformation, and simultaneously achieve the best aesthetic outcomes.
{"title":"History and prospect of melanocytic nevus treatment: A bibliometric analysis","authors":"Zizhen Guo, Lingling Ge, Yuehua Li, Yihui Gu, Wei Wang, Chengjiang Wei, Bin Gu, Qingfeng Li, Zhichao Wang","doi":"10.1016/j.cjprs.2023.10.001","DOIUrl":"https://doi.org/10.1016/j.cjprs.2023.10.001","url":null,"abstract":"Melanocytic nevus is mainly treated by complete or partial removal. However, predicting the risk of malignant transformation of melanocytic nevi and which treatment patients should receive, surgical or non-surgical management, to gain the best results and aesthetic outcomes is controversial. Global literature on melanocytic nevus treatment, published between 1997 and 2022, was scanned using the Web of Science Core Collection database. Microsoft Office Excel, CiteSpace V, VOSviewer, Scimago Graphica, Bibliometrix, and Biblioshiny packages in R were used for the bibliometric analysis to summarize the leading countries, institutions, professors, and research trends in this field. This study included 1 723 articles. Publications and citations exhibited positive trends over the past 20 years. The United States had the most productive organizations and publications in the comprehensive worldwide cooperation network, and China was recently one of the most active major participants. Professor Giovanni Pellacani, whose H-index, G-index, and M-index ranked first in this field, founded a virtual biopsy using reflectance confocal microscopy. In addition, Krengel and Kinsler contributed significantly to diagnosing and treating melanocytic nevi. The top 25 keywords in recent years were mostly about the mechanisms and risk factors for the malignant transformation of nevi. The future trend for melanocytic nevi treatment is to specify genotype-phenotype and genotype-outcome correlations, choose proper therapy to reduce the risk of malignant transformation, and simultaneously achieve the best aesthetic outcomes.","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136093280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.1016/j.cjprs.2023.08.003
Shahryar Cohanzad
Background
This study aimed to evaluate the long-term penile size among patients who underwent extensive metoidioplasty.
Methods
An evaluation was conducted on 7 out of 14 patients (mean age: 29.71 ± 13.76 years) who participated in a 2015 study that introduced a postoperative protocol to improve penile size after extensive metoidioplasty. Five transsexual females (46XX karyotype) and two patients with 5-alpha reductase deficiency were retrospectively followed up in 2023 to assess the long-term efficacy of the protocol at a specialized clinic in a general hospital in Tehran, Iran. All participants were informed about the study and consented to participate.
Results
Five patients achieved increased penile size from their 2015 measurements (mean, 29.00 ± 13.34 mm). Five patients requested a larger sized penile traction device to continue the protocol.
Conclusion
The long-term implementation of this protocol can result in increased penile size. We advise highly motivated patients to continue practicing the protocol to achieve better results.
{"title":"Eight-year follow-up on postoperative improvement protocol in extensive metoidioplasty transgenders: A case series","authors":"Shahryar Cohanzad","doi":"10.1016/j.cjprs.2023.08.003","DOIUrl":"10.1016/j.cjprs.2023.08.003","url":null,"abstract":"<div><h3>Background</h3><p>This study aimed to evaluate the long-term penile size among patients who underwent extensive metoidioplasty.</p></div><div><h3>Methods</h3><p>An evaluation was conducted on 7 out of 14 patients (mean age: 29.71 ± 13.76 years) who participated in a 2015 study that introduced a postoperative protocol to improve penile size after extensive metoidioplasty. Five transsexual females (46XX karyotype) and two patients with 5-alpha reductase deficiency were retrospectively followed up in 2023 to assess the long-term efficacy of the protocol at a specialized clinic in a general hospital in Tehran, Iran. All participants were informed about the study and consented to participate.</p></div><div><h3>Results</h3><p>Five patients achieved increased penile size from their 2015 measurements (mean, 29.00 ± 13.34 mm). Five patients requested a larger sized penile traction device to continue the protocol.</p></div><div><h3>Conclusion</h3><p>The long-term implementation of this protocol can result in increased penile size. We advise highly motivated patients to continue practicing the protocol to achieve better results.</p></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"5 3","pages":"Pages 115-119"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49200770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.1016/j.cjprs.2023.07.002
Daojiang Yu , Jing Wang , Lei Chen , Lu An , Yahui Feng , Sheng Jiang , Shuyu Zhang , Xiaoming Chen , Guozhong Lv
Background
Reconstruction of large scalp defects after tumor resection is common and challenging. Free skin grafting or free flap transfer is always performed. However, these techniques can result in poor functional and cosmetic outcomes.
Methods
In the Second Affiliated Hospital of Soochow University and the Second Affiliated Hospital of Chengdu Medical College, 35 patients underwent jigsaw puzzle flap procedures based on a free-style perforator to repair large scalp defects after tumor resection from May 2013 to November 2022. The key to this procedure was to divide a large defect into several smaller parts that correspond to adjacent free-style perforators around the scalp defect. The free-style perforator flaps were designed in different ways, such as propeller flaps, rotation flaps, and V-Y advancement flaps, which were pedicled with free-style perforators. All of the small flaps were then mobilized to the defect and sutured to each other to create a new, large jigsaw puzzle-like flap to cover the large scalp defect. Finally, all the donor sites were closed directly.
Results
Overall, 35 patients were treated. The average defect size was 72 cm2 (range, 25–91 cm2). All flaps had a satisfactory appearance after follow-up periods of 6 months–10 years. Local tumor recurrence occurred in one case.
Conclusion
The application of a jigsaw puzzle flap based on a free-style perforator is a suitable option for the reconstruction of large scalp defects after resection, yielding satisfactory functional and cosmetic results.
{"title":"Application of a jigsaw puzzle flap based on free-style perforator to repair large scalp defects after tumor resection: A case series","authors":"Daojiang Yu , Jing Wang , Lei Chen , Lu An , Yahui Feng , Sheng Jiang , Shuyu Zhang , Xiaoming Chen , Guozhong Lv","doi":"10.1016/j.cjprs.2023.07.002","DOIUrl":"10.1016/j.cjprs.2023.07.002","url":null,"abstract":"<div><h3>Background</h3><p>Reconstruction of large scalp defects after tumor resection is common and challenging. Free skin grafting or free flap transfer is always performed. However, these techniques can result in poor functional and cosmetic outcomes.</p></div><div><h3>Methods</h3><p>In the Second Affiliated Hospital of Soochow University and the Second Affiliated Hospital of Chengdu Medical College, 35 patients underwent jigsaw puzzle flap procedures based on a free-style perforator to repair large scalp defects after tumor resection from May 2013 to November 2022. The key to this procedure was to divide a large defect into several smaller parts that correspond to adjacent free-style perforators around the scalp defect. The free-style perforator flaps were designed in different ways, such as propeller flaps, rotation flaps, and V-Y advancement flaps, which were pedicled with free-style perforators. All of the small flaps were then mobilized to the defect and sutured to each other to create a new, large jigsaw puzzle-like flap to cover the large scalp defect. Finally, all the donor sites were closed directly.</p></div><div><h3>Results</h3><p>Overall, 35 patients were treated. The average defect size was 72 cm<sup>2</sup> (range, 25–91 cm<sup>2</sup>). All flaps had a satisfactory appearance after follow-up periods of 6 months–10 years. Local tumor recurrence occurred in one case.</p></div><div><h3>Conclusion</h3><p>The application of a jigsaw puzzle flap based on a free-style perforator is a suitable option for the reconstruction of large scalp defects after resection, yielding satisfactory functional and cosmetic results.</p></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"5 3","pages":"Pages 109-114"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47455253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.1016/j.cjprs.2023.08.002
Song Wang , Renrong Lv , Guangqi Xu , Ran Huo
Cutaneomucosal venous malformations (VMCMs) can manifest as sporadic or familial forms, following an autosomal dominant inheritance pattern. This report highlights the case of a 5-year-old girl presenting with a substantial congenital VMCM attributed to a TIE2 mutation, who underwent percutaneous sclerotherapy followed by surgery. The clinical, three-dimensional computed tomographic angiography (3D-CTA), as well as pathological and genetic findings concerning a patient with an extensive VMCM in the left pro-axillary region, are elucidated. The genetic analysis in this patient verified a missense mutation (c.2545T>C) in TIE2, confirming familial VMCMs. The combined strategy integrating percutaneous sclerotherapy and surgical excision is the most efficacious approach for managing large VMCMs and can successfully attain therapeutic goals.
{"title":"Integrated percutaneous sclerotherapy and surgical intervention for giant cutaneomucosal venous malformation from TIE2 mutation: A case report","authors":"Song Wang , Renrong Lv , Guangqi Xu , Ran Huo","doi":"10.1016/j.cjprs.2023.08.002","DOIUrl":"10.1016/j.cjprs.2023.08.002","url":null,"abstract":"<div><p>Cutaneomucosal venous malformations (VMCMs) can manifest as sporadic or familial forms, following an autosomal dominant inheritance pattern. This report highlights the case of a 5-year-old girl presenting with a substantial congenital VMCM attributed to a TIE2 mutation, who underwent percutaneous sclerotherapy followed by surgery. The clinical, three-dimensional computed tomographic angiography (3D-CTA), as well as pathological and genetic findings concerning a patient with an extensive VMCM in the left pro-axillary region, are elucidated. The genetic analysis in this patient verified a missense mutation (c.2545T>C) in TIE2, confirming familial VMCMs. The combined strategy integrating percutaneous sclerotherapy and surgical excision is the most efficacious approach for managing large VMCMs and can successfully attain therapeutic goals.</p></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"5 3","pages":"Pages 126-129"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47725144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.1016/j.cjprs.2023.07.001
Xiaorong Ma , Xiaoting Sun , Yuexin Shi , Kaiyang Lv , Wenbin Chen
We report a case of a 74-year-old female with hypopharyngeal cancer who developed a pharyngoesophageal fistula and neck skin defect after total laryngectomy. To reconstruct the hypopharynx, upper esophagus, and neck skin defect, we used a supraclavicular artery island flap (SCAIF) for one-stage reconstruction. SCAIF offered reliable blood supply, minimal donor site morbidity, and excellent cosmetic outcomes. Although a small portion of the flap developed necrosis, it healed without surgical intervention. We also conducted a literature review of previously published articles on SCAIF for head and neck reconstruction. Our review highlights the advantages and limitations of SCAIF as a promising option for one-stage reconstruction of complex hypopharyngeal and upper esophageal defects with neck skin defects in selected patients. This case report provides valuable insights into the use of SCAIF in complex head and neck reconstructions, which can help improve patient outcomes and quality of life.
{"title":"Supraclavicular artery island flap for reconstruction of hypopharynx and upper esophagus defects: A case report and literature review","authors":"Xiaorong Ma , Xiaoting Sun , Yuexin Shi , Kaiyang Lv , Wenbin Chen","doi":"10.1016/j.cjprs.2023.07.001","DOIUrl":"10.1016/j.cjprs.2023.07.001","url":null,"abstract":"<div><p>We report a case of a 74-year-old female with hypopharyngeal cancer who developed a pharyngoesophageal fistula and neck skin defect after total laryngectomy. To reconstruct the hypopharynx, upper esophagus, and neck skin defect, we used a supraclavicular artery island flap (SCAIF) for one-stage reconstruction. SCAIF offered reliable blood supply, minimal donor site morbidity, and excellent cosmetic outcomes. Although a small portion of the flap developed necrosis, it healed without surgical intervention. We also conducted a literature review of previously published articles on SCAIF for head and neck reconstruction. Our review highlights the advantages and limitations of SCAIF as a promising option for one-stage reconstruction of complex hypopharyngeal and upper esophageal defects with neck skin defects in selected patients. This case report provides valuable insights into the use of SCAIF in complex head and neck reconstructions, which can help improve patient outcomes and quality of life.</p></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"5 3","pages":"Pages 130-135"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45055865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.1016/j.cjprs.2023.09.002
Jingwei Zhou, Chen Hua, Xi Yang, Yuxi Chen, Yunbo Jin, Xiaoxi Lin
Arteriovenous malformations (AVMs) are aggressive congenital high-flow vascular anomalies, in which the feeding artery and draining vein are connected through fistulas without normal capillary networks. In severe cases, the condition may cause swelling, ulceration, bleeding, and even heart failure. Various treatment options are available for AVMs, including laser, surgical resection, embolization, and targeted drug therapy. With the development of endovascular treatment technology, absolute ethanol embolization of AVMs has become one of the first-line therapies owing to its sustained efficacy and low recurrence rate. However, administration of this therapy is challenging and may lead to serious complications if inappropriately managed. In this article, we reviewed and summarized previous clinical articles, literature reviews, and clinical trial data to comprehensively describe clinical manifestations of AVMs, the mechanism of ethanol embolotherapy, key points in treatment and management of complications, and issues that need to be addressed. We expect to provide a reliable information reference source for clinical physicians and researchers.
{"title":"Absolute ethanol embolization for treatment of peripheral arteriovenous malformations","authors":"Jingwei Zhou, Chen Hua, Xi Yang, Yuxi Chen, Yunbo Jin, Xiaoxi Lin","doi":"10.1016/j.cjprs.2023.09.002","DOIUrl":"https://doi.org/10.1016/j.cjprs.2023.09.002","url":null,"abstract":"<div><p>Arteriovenous malformations (AVMs) are aggressive congenital high-flow vascular anomalies, in which the feeding artery and draining vein are connected through fistulas without normal capillary networks. In severe cases, the condition may cause swelling, ulceration, bleeding, and even heart failure. Various treatment options are available for AVMs, including laser, surgical resection, embolization, and targeted drug therapy. With the development of endovascular treatment technology, absolute ethanol embolization of AVMs has become one of the first-line therapies owing to its sustained efficacy and low recurrence rate. However, administration of this therapy is challenging and may lead to serious complications if inappropriately managed. In this article, we reviewed and summarized previous clinical articles, literature reviews, and clinical trial data to comprehensively describe clinical manifestations of AVMs, the mechanism of ethanol embolotherapy, key points in treatment and management of complications, and issues that need to be addressed. We expect to provide a reliable information reference source for clinical physicians and researchers.</p></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"5 3","pages":"Pages 136-140"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49804342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.1016/j.cjprs.2023.06.002
Victoria Ivanovna Polshina , Maria Cervatiuc , Igor Vladimirovich Reshetov , Alim Arsenovich Nebejev , Eldor Jonnazarov
Background
Damage to the skin and underlying tissues due to thermal burns is relevant. Despite the success of modern medicine, repairing thermal damage to the skin is a difficult task in reconstructive plastic surgery because of the nature of the damage and the regenerative features. Characteristic post-burn changes are associated with different depths of damage when areas of deep damage are combined with more superficial areas.
Methods
We described a clinical case of the staged surgical treatment of a cicatricial deformity of the buccal-periorbital-perioral region resulting from a childhood burn injury from a hot object. The 44-year-old patient complained of an aesthetic and functional deformity of the buccal-periorbital-perioral region and had previously undergone repeated nonsurgical corrections.
Results
A comprehensive approach to the surgical treatment of a patient with post-burn deformities using a diplene adhesive membrane directly affected the stage of the surgical treatment and contributed to improved functional and aesthetic results.
Conclusion
The positive treatment results with preserved contraction and relaxation processes of the facial muscles as well as satisfactory aesthetic results allow us to recommend the use of a biodegradable diplene film during facial reconstructive operations.
{"title":"A comprehensive approach to the delayed treatment of post-burn facial scars","authors":"Victoria Ivanovna Polshina , Maria Cervatiuc , Igor Vladimirovich Reshetov , Alim Arsenovich Nebejev , Eldor Jonnazarov","doi":"10.1016/j.cjprs.2023.06.002","DOIUrl":"10.1016/j.cjprs.2023.06.002","url":null,"abstract":"<div><h3>Background</h3><p>Damage to the skin and underlying tissues due to thermal burns is relevant. Despite the success of modern medicine, repairing thermal damage to the skin is a difficult task in reconstructive plastic surgery because of the nature of the damage and the regenerative features. Characteristic post-burn changes are associated with different depths of damage when areas of deep damage are combined with more superficial areas.</p></div><div><h3>Methods</h3><p>We described a clinical case of the staged surgical treatment of a cicatricial deformity of the buccal-periorbital-perioral region resulting from a childhood burn injury from a hot object. The 44-year-old patient complained of an aesthetic and functional deformity of the buccal-periorbital-perioral region and had previously undergone repeated nonsurgical corrections.</p></div><div><h3>Results</h3><p>A comprehensive approach to the surgical treatment of a patient with post-burn deformities using a diplene adhesive membrane directly affected the stage of the surgical treatment and contributed to improved functional and aesthetic results.</p></div><div><h3>Conclusion</h3><p>The positive treatment results with preserved contraction and relaxation processes of the facial muscles as well as satisfactory aesthetic results allow us to recommend the use of a biodegradable diplene film during facial reconstructive operations.</p></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"5 3","pages":"Pages 159-162"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48659766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.1016/j.cjprs.2023.09.001
Zi’an Xu , Jingwei Zhou , Yuxi Chen, Xi Yang, Chen Hua, Yunbo Jin, Xiaoxi Lin
Arteriovenous malformations (AVMs) are serious congenital vascular anomalies in which the arteries connect directly with veins without capillaries. This condition will continue to worsen without proper intervention and cause ulcers, repeated hemorrhages, and even cardiac insufficiency. Primary treatment options for AVMs include surgery and interventional treatment; however, they are associated with high risk and recurrence rates. Recent studies revealed that excessive activation of the Ras/MAPK pathway can induce the formation and development of peripheral AVM, whereas MEK inhibitors can effectively control nidus progression, making them a potential novel treatment for AVM. This review provides an up-to-date overview of correlated laboratory and clinical research to provide information for further research and clinical practice.
{"title":"MEK inhibitors for the treatment of extracranial arteriovenous malformations","authors":"Zi’an Xu , Jingwei Zhou , Yuxi Chen, Xi Yang, Chen Hua, Yunbo Jin, Xiaoxi Lin","doi":"10.1016/j.cjprs.2023.09.001","DOIUrl":"https://doi.org/10.1016/j.cjprs.2023.09.001","url":null,"abstract":"<div><p>Arteriovenous malformations (AVMs) are serious congenital vascular anomalies in which the arteries connect directly with veins without capillaries. This condition will continue to worsen without proper intervention and cause ulcers, repeated hemorrhages, and even cardiac insufficiency. Primary treatment options for AVMs include surgery and interventional treatment; however, they are associated with high risk and recurrence rates. Recent studies revealed that excessive activation of the Ras/MAPK pathway can induce the formation and development of peripheral AVM, whereas MEK inhibitors can effectively control nidus progression, making them a potential novel treatment for AVM. This review provides an up-to-date overview of correlated laboratory and clinical research to provide information for further research and clinical practice.</p></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"5 3","pages":"Pages 141-144"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49804343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.1016/j.cjprs.2023.09.003
Ke Chen , Yikang Yu , Jialu Shu , Binbin Zhang , Gang Wang , Bin Wu
Background
Diabetic foot ulcers (DBFU) are one of the main complications of diabetes. Platelet-rich plasma (PRP) treatment is a commonly used treatment option. Tibial transverse transport (TTT) also has a therapeutic effect on DBFU. Some studies have found that the TTT combined with PRP (TTT&PRP) has a significant effect on DBFU.
Methods
PubMed, Cochrane Library, Web of Science, EMBASE, Chinese Biomedical Literature, CNKI, VIP, and Wanfang databases were used to find literature on the treatment of DBFUs using the TTT and PRP treatment according to the inclusion criteria. The specific inclusion criteria are as follows: (1) research type: clinical controlled trials, including retrospective cohort and randomized controlled studies; (2) diagnosis of DBFUs that does not include a definitively diagnosed traumatic ulcer; (3) original materials of Chinese and English literature published in full text. The exclusion criteria are: (1) the research group was not defined or grouped; (2) nonrandomized controlled trials, non-cohort studies, non-case-control studies, retrospective studies, and case reports; (3) repetitive research and animal experimentation; (4) ulcers caused by other diseases; (5) conservative treatment or no use of invasive treatment methods. Review Manager software (version 5.3) was used to conduct a meta-analysis of the included results.
Result
The literature included 6 randomized controlled studies, including 508 patients, 254 patients in the PRP treatment group, and 254 patients in the TTT&PRP group. The meta-analysis results showed that in terms of treatment efficacy, the TTT&PRP combined treatment group had a higher efficacy than the PRP group. After treatment, the TTT&PRP group had better treatment effects in psychological function, physiological function, and social function compared to the PRP group. After treatment, the TTT&PRP group showed a significant increase in serum epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), and platelet-derived growth factor (PDGF) levels compared to the PRP group. In terms of wound healing after treatment, the TTT&PRP group performed better than the PRP group in terms of postoperative wound reduction rate, bacterial clearance rate, granulation tissue coverage rate, and granulation tissue growth thickness.
Conclusion
TTT combined with PRP was more effective than PRP alone in treating DBFUs.
{"title":"Efficacy of tibial transverse transport combined with platelet-rich plasma versus platelet-rich plasma alone in the treatment of diabetic foot ulcers: A meta-analysis","authors":"Ke Chen , Yikang Yu , Jialu Shu , Binbin Zhang , Gang Wang , Bin Wu","doi":"10.1016/j.cjprs.2023.09.003","DOIUrl":"https://doi.org/10.1016/j.cjprs.2023.09.003","url":null,"abstract":"<div><h3>Background</h3><p>Diabetic foot ulcers (DBFU) are one of the main complications of diabetes. Platelet-rich plasma (PRP) treatment is a commonly used treatment option. Tibial transverse transport (TTT) also has a therapeutic effect on DBFU. Some studies have found that the TTT combined with PRP (TTT&PRP) has a significant effect on DBFU.</p></div><div><h3>Methods</h3><p>PubMed, Cochrane Library, Web of Science, EMBASE, Chinese Biomedical Literature, CNKI, VIP, and Wanfang databases were used to find literature on the treatment of DBFUs using the TTT and PRP treatment according to the inclusion criteria. The specific inclusion criteria are as follows: (1) research type: clinical controlled trials, including retrospective cohort and randomized controlled studies; (2) diagnosis of DBFUs that does not include a definitively diagnosed traumatic ulcer; (3) original materials of Chinese and English literature published in full text. The exclusion criteria are: (1) the research group was not defined or grouped; (2) nonrandomized controlled trials, non-cohort studies, non-case-control studies, retrospective studies, and case reports; (3) repetitive research and animal experimentation; (4) ulcers caused by other diseases; (5) conservative treatment or no use of invasive treatment methods. Review Manager software (version 5.3) was used to conduct a meta-analysis of the included results.</p></div><div><h3>Result</h3><p>The literature included 6 randomized controlled studies, including 508 patients, 254 patients in the PRP treatment group, and 254 patients in the TTT&PRP group. The meta-analysis results showed that in terms of treatment efficacy, the TTT&PRP combined treatment group had a higher efficacy than the PRP group. After treatment, the TTT&PRP group had better treatment effects in psychological function, physiological function, and social function compared to the PRP group. After treatment, the TTT&PRP group showed a significant increase in serum epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), and platelet-derived growth factor (PDGF) levels compared to the PRP group. In terms of wound healing after treatment, the TTT&PRP group performed better than the PRP group in terms of postoperative wound reduction rate, bacterial clearance rate, granulation tissue coverage rate, and granulation tissue growth thickness.</p></div><div><h3>Conclusion</h3><p>TTT combined with PRP was more effective than PRP alone in treating DBFUs.</p></div>","PeriodicalId":65600,"journal":{"name":"Chinese Journal of Plastic and Reconstructive Surgery","volume":"5 3","pages":"Pages 145-153"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49804346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}