Pub Date : 2019-10-10DOI: 10.3760/CMA.J.ISSN.1005-054X.2019.05.002
Xiangshui Sun, Li Jiang, Fei Wang, Bang Wang
Objective To compare the clinical efficacy of non-operative and surgical treatment of distal clavicle fractures in older children. Methods From January 2011 to March 2018, 41 older children with distal clavicle fractures were treated. Among them, 24 cases underwent non-operative treatment, shoulder abduction brace fixation for 4 to 6 weeks (non-operation group); while 17 cases underwent surgical treatment, open reduction and Kirschner wire internal fixation of the fractures on the affected side, and shoulder abduction brace fixation for 4 to 6 weeks (operation group). The fracture healing time, Constant-Murley shoulder function score and complication rate of the two groups were compared and analyzed. Results All the 41 cases were follow-up for 3 to 17 months, with an average of 8.4 months. There was no significant difference in gender, age and fracture side between the two groups, so two groups were comparable. All the incisions in the operation group achieved primary healing. X-ray examination showed that there was continuous callus formation at the fracture end and Kirschner wire was removed. The fracture healing time was (44.3±6.7) days. No early complications such as infection occurred. In the non-operation group, X-ray examination showed bone healing at the fracture end. The healing time was (41.7±7.6) days. At the last follow-up, there were no complications such as malunion of fracture, premature epiphyseal closure and obvious shoulder dysfunction in both groups. Constant-Murley shoulder joint function score: non-operative group was (97.7±4.7) points, while operation group was (96.5±3.7) points. There was no significant difference between the two groups (P=0.32). Conclusion Non-operative treatment of the distal clavicle fractures in older children has the same effect as surgical treatment. However, non-operative treatment has the advantages of less trauma, low cost and no need of secondary surgical removal of internal fixation. Key words: Clavicle; Fractures,bone; Child
{"title":"Comparison of the efficacy of non-operative and surgical treatment of distal clavicle fractures in older children","authors":"Xiangshui Sun, Li Jiang, Fei Wang, Bang Wang","doi":"10.3760/CMA.J.ISSN.1005-054X.2019.05.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-054X.2019.05.002","url":null,"abstract":"Objective \u0000To compare the clinical efficacy of non-operative and surgical treatment of distal clavicle fractures in older children. \u0000 \u0000 \u0000Methods \u0000From January 2011 to March 2018, 41 older children with distal clavicle fractures were treated. Among them, 24 cases underwent non-operative treatment, shoulder abduction brace fixation for 4 to 6 weeks (non-operation group); while 17 cases underwent surgical treatment, open reduction and Kirschner wire internal fixation of the fractures on the affected side, and shoulder abduction brace fixation for 4 to 6 weeks (operation group). The fracture healing time, Constant-Murley shoulder function score and complication rate of the two groups were compared and analyzed. \u0000 \u0000 \u0000Results \u0000All the 41 cases were follow-up for 3 to 17 months, with an average of 8.4 months. There was no significant difference in gender, age and fracture side between the two groups, so two groups were comparable. All the incisions in the operation group achieved primary healing. X-ray examination showed that there was continuous callus formation at the fracture end and Kirschner wire was removed. The fracture healing time was (44.3±6.7) days. No early complications such as infection occurred. In the non-operation group, X-ray examination showed bone healing at the fracture end. The healing time was (41.7±7.6) days. At the last follow-up, there were no complications such as malunion of fracture, premature epiphyseal closure and obvious shoulder dysfunction in both groups. Constant-Murley shoulder joint function score: non-operative group was (97.7±4.7) points, while operation group was (96.5±3.7) points. There was no significant difference between the two groups (P=0.32). \u0000 \u0000 \u0000Conclusion \u0000Non-operative treatment of the distal clavicle fractures in older children has the same effect as surgical treatment. However, non-operative treatment has the advantages of less trauma, low cost and no need of secondary surgical removal of internal fixation. \u0000 \u0000 \u0000Key words: \u0000Clavicle; Fractures,bone; Child","PeriodicalId":67383,"journal":{"name":"中华手外科杂志","volume":"35 1","pages":"325-328"},"PeriodicalIF":0.0,"publicationDate":"2019-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48819509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective To explore the clinical efficacy of absorbable rod in the treatment of metacarpal fractures under the guidance of accelerated rehabilitation surgery concept. Methods From August 2016 to August 2018, 53 patients with long oblique and spiral metacarpal fractures were treated with absorbable rod by fixation perpendicular to the fracture line. The patients were divided into observation group and control group according to whether they were treated with the concept of accelerated rehabilitation surgery during perioperative period or not. There were 24 cases in the observation group (28 places) and 29 cases in the control group (31 places). The visual analogue scale (VAS) on the first day after operation, the time when the active range of motion of metacarpophalangeal joint returned to normal, the time of fracture healing and the functional evaluation results of the injured hand at the last follow-up were compared between the two groups. Results All the patients were follow-up for 1 to 12 months with an average of 9.2 months. All the incisions achieved primary healing and all the fractures were healed. On the first day after operation, VAS and the recovery time of metacarpophalangeal joint activity in the observation group were (2.64±0.81) points and (19.35±2.12) days, respectively, which were significantly lower than those in the control group (3.42±1.13) points and (28.63±1.31) days. The differences were statistically significant (t=-2.920, -14.665, P 0.05). There was no significant difference in hand function evaluation between the two groups at the last follow-up (χ2=0.045, P>0.05). Conclusion The technique of absorbable rod by fixation perpendicular to the fracture line for long oblique or spiral metacarpal fractures is a safe and effective surgical method. With the guidance of accelerated rehabilitation surgery concept, hand function can be better restored and satisfactory clinical efficacy can be obtained. Key words: Metacarpal bones; Fractures,bone; Absorbable rod; Accelerated rehabilitation surgery
目的探讨在加速康复外科理念指导下，可吸收棒治疗掌骨骨折的临床疗效。方法2016年8月至2018年8月，对53例长斜螺旋型掌骨骨折患者采用垂直于骨折线固定的可吸收棒治疗。根据围手术期患者是否接受加速康复手术理念治疗分为观察组和对照组。观察组24例(28处)，对照组29例(31处)。比较两组患者术后第1天视觉模拟评分(VAS)、掌指关节活动范围恢复正常时间、骨折愈合时间及末次随访时损伤手功能评价结果。结果所有患者随访1 ~ 12个月，平均9.2个月。所有切口均初步愈合，骨折均愈合。术后第1天，观察组VAS评分为(2.64±0.81)分，掌指关节活动恢复时间为(19.35±2.12)d，显著低于对照组(3.42±1.13)分，显著低于对照组(28.63±1.31)d。差异有统计学意义(t=-2.920， -14.665, P 0.05)。末次随访时两组患者手功能评分差异无统计学意义(χ2=0.045, P < 0.05)。结论可吸收棒垂直于骨折线固定治疗长斜或螺旋型掌骨骨折是一种安全有效的手术方法。在加速康复手术理念的指导下，手部功能可以得到更好的恢复，获得满意的临床疗效。关键词:掌骨;骨折,骨;可吸收棒;加速康复手术
{"title":"Application of accelerated rehabilitation surgery concept in the treatment of metacarpal fractures with absorbable rods","authors":"Yan Wang, Yong Wu, Zhanyuan Gao, Xiaomei Lu, Zhao-de Zhang, Wenkai Chang","doi":"10.3760/CMA.J.ISSN.1005-054X.2019.05.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-054X.2019.05.012","url":null,"abstract":"Objective \u0000To explore the clinical efficacy of absorbable rod in the treatment of metacarpal fractures under the guidance of accelerated rehabilitation surgery concept. \u0000 \u0000 \u0000Methods \u0000From August 2016 to August 2018, 53 patients with long oblique and spiral metacarpal fractures were treated with absorbable rod by fixation perpendicular to the fracture line. The patients were divided into observation group and control group according to whether they were treated with the concept of accelerated rehabilitation surgery during perioperative period or not. There were 24 cases in the observation group (28 places) and 29 cases in the control group (31 places). The visual analogue scale (VAS) on the first day after operation, the time when the active range of motion of metacarpophalangeal joint returned to normal, the time of fracture healing and the functional evaluation results of the injured hand at the last follow-up were compared between the two groups. \u0000 \u0000 \u0000Results \u0000All the patients were follow-up for 1 to 12 months with an average of 9.2 months. All the incisions achieved primary healing and all the fractures were healed. On the first day after operation, VAS and the recovery time of metacarpophalangeal joint activity in the observation group were (2.64±0.81) points and (19.35±2.12) days, respectively, which were significantly lower than those in the control group (3.42±1.13) points and (28.63±1.31) days. The differences were statistically significant (t=-2.920, -14.665, P 0.05). There was no significant difference in hand function evaluation between the two groups at the last follow-up (χ2=0.045, P>0.05). \u0000 \u0000 \u0000Conclusion \u0000The technique of absorbable rod by fixation perpendicular to the fracture line for long oblique or spiral metacarpal fractures is a safe and effective surgical method. With the guidance of accelerated rehabilitation surgery concept, hand function can be better restored and satisfactory clinical efficacy can be obtained. \u0000 \u0000 \u0000Key words: \u0000Metacarpal bones; Fractures,bone; Absorbable rod; Accelerated rehabilitation surgery","PeriodicalId":67383,"journal":{"name":"中华手外科杂志","volume":"35 1","pages":"351-353"},"PeriodicalIF":0.0,"publicationDate":"2019-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41896901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-10DOI: 10.3760/CMA.J.ISSN.1005-054X.2019.05.020
Jiangming Qi, K. Gong, Dongsheng Li, Dawei Zhang
Objective To compare the motor nerve conduction velocity (MNCV) of ulnar nerve between elbow joint natural extension and extreme flexion for 2 minutes in patients with cubital tunnel syndrome, and to explore the relationship between MNCV of ulnar nerve and elbow joint flexion and extension in patients with cubital tunnel syndrome. Methods Under two different conditions of elbow joint natural extension and extreme flexion for 2 minutes, 45 patients with cubital tunnel syndrome were examined by two methods: recording electrodes in the abductor digitorum minimi and the first dorsal interosseous muscle, and measuring the MNCV of ulnar nerve in the elbow tunnel segment. The MNCV of ulnar nerve was V1 at elbow extension and V2 at elbow flexion for 2 minutes when recording electrodes were in the abductor digitorum minimi; the MNCV of ulnar nerve was V3 at elbow extension and V4 at elbow flexion for 2 minutes when recording electrodes were in the first dorsal interosseous muscle. Matched-pair t-tests were performed for V1 and V2, V3 and V4, V1 and V3, V2 and V4, respectively. Results The MNCV of ulnar nerve in the elbow tunnel segment in the 45 patients were V1(29.47±8.37) m/s、V2(28.32±7.85) m/s、V3(27.91±9.62) m/s、V4(26.76±8.58) m/s, respectively. There was no significant difference in paired t test between V1 and V2, V3 and V4, V1 and V3, V2 and V4 (P>0.05). Conclusion There was no significant difference in MNCV of ulnar nerve in elbow segment between elbow joint extension and flexion in patients with cubital tunnel syndrome. There was no significant difference in the results of electromyogram between abductor digitorum minimi and first dorsal interosseous muscle. The results showed that elbow flexion or elbow extension had no significant effect on the results of electromyography in patients with cubital tunnel syndrome. Key words: Cubital tunnel syndrome; Ulnar nerve; Motor nerve conduction velocity; Elbow flexion test
{"title":"A comparative study of motor nerve conduction velocity of ulnar nerve between elbow extension and elbow flexion in patients with cubital tunnel syndrome","authors":"Jiangming Qi, K. Gong, Dongsheng Li, Dawei Zhang","doi":"10.3760/CMA.J.ISSN.1005-054X.2019.05.020","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-054X.2019.05.020","url":null,"abstract":"Objective \u0000To compare the motor nerve conduction velocity (MNCV) of ulnar nerve between elbow joint natural extension and extreme flexion for 2 minutes in patients with cubital tunnel syndrome, and to explore the relationship between MNCV of ulnar nerve and elbow joint flexion and extension in patients with cubital tunnel syndrome. \u0000 \u0000 \u0000Methods \u0000Under two different conditions of elbow joint natural extension and extreme flexion for 2 minutes, 45 patients with cubital tunnel syndrome were examined by two methods: recording electrodes in the abductor digitorum minimi and the first dorsal interosseous muscle, and measuring the MNCV of ulnar nerve in the elbow tunnel segment. The MNCV of ulnar nerve was V1 at elbow extension and V2 at elbow flexion for 2 minutes when recording electrodes were in the abductor digitorum minimi; the MNCV of ulnar nerve was V3 at elbow extension and V4 at elbow flexion for 2 minutes when recording electrodes were in the first dorsal interosseous muscle. Matched-pair t-tests were performed for V1 and V2, V3 and V4, V1 and V3, V2 and V4, respectively. \u0000 \u0000 \u0000Results \u0000The MNCV of ulnar nerve in the elbow tunnel segment in the 45 patients were V1(29.47±8.37) m/s、V2(28.32±7.85) m/s、V3(27.91±9.62) m/s、V4(26.76±8.58) m/s, respectively. There was no significant difference in paired t test between V1 and V2, V3 and V4, V1 and V3, V2 and V4 (P>0.05). \u0000 \u0000 \u0000Conclusion \u0000There was no significant difference in MNCV of ulnar nerve in elbow segment between elbow joint extension and flexion in patients with cubital tunnel syndrome. There was no significant difference in the results of electromyogram between abductor digitorum minimi and first dorsal interosseous muscle. The results showed that elbow flexion or elbow extension had no significant effect on the results of electromyography in patients with cubital tunnel syndrome. \u0000 \u0000 \u0000Key words: \u0000Cubital tunnel syndrome; Ulnar nerve; Motor nerve conduction velocity; Elbow flexion test","PeriodicalId":67383,"journal":{"name":"中华手外科杂志","volume":"35 1","pages":"377-379"},"PeriodicalIF":0.0,"publicationDate":"2019-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46284016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-10DOI: 10.3760/CMA.J.ISSN.1005-054X.2019.05.007
Xiaoling Zhou, Xue-yuan Li, Hao-liang Hu, Miao Yu, Yi Li
Objective To compare the clinical efficacy of operative treatment and conservative treatment by short finger brace for closed tendinous mallet finger. Methods From October 2014 to December 2016, 104 patients with closed tendinous mallet finger were treated. Among them, 54 patients underwent operative treatment (group A) and 50 patients underwent conservative treatment by short finger brace (group B). All the patients were followed up clinically. The active range of motion, pain and complications of affected fingers were recorded. The clinical efficacy was evaluated according to Abouna and Brown functional evaluation criteria. The difference of clinical efficacy between the two groups was statistically analyzed. Results The follow-up time of group A was 5 to 12 months with an average of 6.3 months, while that of group B was 4 to 14 months with an average of 7.1 months. According to Abouna and Brown functional evaluation criteria, the results were rated as excellent in 30 cases, good in 15 cases, poor in 9 cases with the excellent and good rate being 83.3% in group A; while the results were rated as excellent in 28 cases, good in 16 cases, poor in 6 cases with the excellent and good rate being 88.0% in group B. There was no significant difference in the excellent and good rate between the two groups, and there was no significant difference in the degree of pain between the two groups (P>0.05). The operation of group A was complicated with complications such as wound infection, foreign body reaction, nail bed deformity and so on. In group B, only one case had slight pressure sore after treatment, which returned to normal after proper nursing. Conclusion The clinical efficacy of conservative treatment by short finger brace for closed tendinous mallet finger is not significantly different from that of operative treatment. However, the conservative treatment has the advantages of simple operation, low cost and fewer complications. Key words: Tendon injuries; Comparative effectiveness research; Mallet finger; Conservative treatment; Operative treatment
{"title":"Retrospective study for clinical efficacy comparison of operative treatment and conservative treatment by short finger brace for closed tendinous mallet finger","authors":"Xiaoling Zhou, Xue-yuan Li, Hao-liang Hu, Miao Yu, Yi Li","doi":"10.3760/CMA.J.ISSN.1005-054X.2019.05.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-054X.2019.05.007","url":null,"abstract":"Objective \u0000To compare the clinical efficacy of operative treatment and conservative treatment by short finger brace for closed tendinous mallet finger. \u0000 \u0000 \u0000Methods \u0000From October 2014 to December 2016, 104 patients with closed tendinous mallet finger were treated. Among them, 54 patients underwent operative treatment (group A) and 50 patients underwent conservative treatment by short finger brace (group B). All the patients were followed up clinically. The active range of motion, pain and complications of affected fingers were recorded. The clinical efficacy was evaluated according to Abouna and Brown functional evaluation criteria. The difference of clinical efficacy between the two groups was statistically analyzed. \u0000 \u0000 \u0000Results \u0000The follow-up time of group A was 5 to 12 months with an average of 6.3 months, while that of group B was 4 to 14 months with an average of 7.1 months. According to Abouna and Brown functional evaluation criteria, the results were rated as excellent in 30 cases, good in 15 cases, poor in 9 cases with the excellent and good rate being 83.3% in group A; while the results were rated as excellent in 28 cases, good in 16 cases, poor in 6 cases with the excellent and good rate being 88.0% in group B. There was no significant difference in the excellent and good rate between the two groups, and there was no significant difference in the degree of pain between the two groups (P>0.05). The operation of group A was complicated with complications such as wound infection, foreign body reaction, nail bed deformity and so on. In group B, only one case had slight pressure sore after treatment, which returned to normal after proper nursing. \u0000 \u0000 \u0000Conclusion \u0000The clinical efficacy of conservative treatment by short finger brace for closed tendinous mallet finger is not significantly different from that of operative treatment. However, the conservative treatment has the advantages of simple operation, low cost and fewer complications. \u0000 \u0000 \u0000Key words: \u0000Tendon injuries; Comparative effectiveness research; Mallet finger; Conservative treatment; Operative treatment","PeriodicalId":67383,"journal":{"name":"中华手外科杂志","volume":"35 1","pages":"337-339"},"PeriodicalIF":0.0,"publicationDate":"2019-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43284607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-10DOI: 10.3760/CMA.J.ISSN.1005-054X.2019.04.014
Yanyan Fu, Cheng Lu, Yichen Dou, Laijin Lu
Objective To explore the clinical treatment of deep branch of ulnar nerve injury. Methods From January 2013 to August 2018, 20 cases of deep branch of ulnar nerve injury were treated. The etiology, diagnosis and surgical treatment of deep branch of ulnar nerve injury were analyzed retrospectively. Results All the patients were follow-up for 8.9 to 68.1 months with an average of 37.0 months. According to the criteria of upper extremity functional evaluation issued by the Hand Surgery Society of the Chinese Medical Association, the results were rated as excellent in 11 cases, good in 4 cases, fair in 4 cases and poor in 1 case. Conclusion The injury of the deep branch of ulnar nerve requires early diagnosis and early surgical treatment. The effect of nerve suture or neurolysis is related to the degree of neurodegeneration or intrinsic myofibrosis. Key words: Ulnar nerve; Treatment outcome; Deep branch; Diagnosis; Surgical treatment
{"title":"Treatment of deep branch injury of ulnar nerve","authors":"Yanyan Fu, Cheng Lu, Yichen Dou, Laijin Lu","doi":"10.3760/CMA.J.ISSN.1005-054X.2019.04.014","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-054X.2019.04.014","url":null,"abstract":"Objective \u0000To explore the clinical treatment of deep branch of ulnar nerve injury. \u0000 \u0000 \u0000Methods \u0000From January 2013 to August 2018, 20 cases of deep branch of ulnar nerve injury were treated. The etiology, diagnosis and surgical treatment of deep branch of ulnar nerve injury were analyzed retrospectively. \u0000 \u0000 \u0000Results \u0000All the patients were follow-up for 8.9 to 68.1 months with an average of 37.0 months. According to the criteria of upper extremity functional evaluation issued by the Hand Surgery Society of the Chinese Medical Association, the results were rated as excellent in 11 cases, good in 4 cases, fair in 4 cases and poor in 1 case. \u0000 \u0000 \u0000Conclusion \u0000The injury of the deep branch of ulnar nerve requires early diagnosis and early surgical treatment. The effect of nerve suture or neurolysis is related to the degree of neurodegeneration or intrinsic myofibrosis. \u0000 \u0000 \u0000Key words: \u0000Ulnar nerve; Treatment outcome; Deep branch; Diagnosis; Surgical treatment","PeriodicalId":67383,"journal":{"name":"中华手外科杂志","volume":"35 1","pages":"275-278"},"PeriodicalIF":0.0,"publicationDate":"2019-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41574573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-10DOI: 10.3760/CMA.J.ISSN.1005-054X.2019.04.021
Zhen‐tang Wang, Yingna Bao, Chang Li, Qi‐cheng Ai‐Xin‐Jue‐Luo, Yongqiang Fu
Objective To investigate the inhibitory effect and mechanism of compound angelica injection on the proliferation of human fibroblasts. Methods Compound angelica injection with 10, 20, 40 and 80 mg/ml concentrations was administered on human fibroblasts respectively. MTS method was used to detect the proliferation level of human fibroblasts after 48 and 72 hours. The expression level of TGF-β1 was detected by ELISA. Real-time PCR was used to detect the change level of TGF-β1 after compound angelica injection. Results MTS results showed that the proliferation of fibroblasts was inhibited in 20, 40, 80 mg/ml group (P<0.05); real-time PCR results showed that the transcription level of TGF-β1 in fibroblasts decreased in 10, 20, 40 mg/ml group compared with the control group 48 hours after the treatment of compound angelica injection (P<0.05). ELISA results showed that the expression of TGF-β1 was inhibited with the increase of drug concentration 48 hours after the treatment of compound angelica injection (P<0.05). Conclusion Compound angelica injection can inhibit the expression of TGF-β1 in human fibroblasts, suggesting that it can inhibit the proliferation of human fibroblasts, and the inhibition level is concentration-dependent after a certain period of time, which may affect the occurrence of tendon adhesion. Key words: Fibroblasts; Angelica sinensis; Tendon adhesion; TGF-β1
{"title":"The study of inhibitory effect of compound angelica injection on fibroblast proliferation in tendon adhesion","authors":"Zhen‐tang Wang, Yingna Bao, Chang Li, Qi‐cheng Ai‐Xin‐Jue‐Luo, Yongqiang Fu","doi":"10.3760/CMA.J.ISSN.1005-054X.2019.04.021","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-054X.2019.04.021","url":null,"abstract":"Objective \u0000To investigate the inhibitory effect and mechanism of compound angelica injection on the proliferation of human fibroblasts. \u0000 \u0000 \u0000Methods \u0000Compound angelica injection with 10, 20, 40 and 80 mg/ml concentrations was administered on human fibroblasts respectively. MTS method was used to detect the proliferation level of human fibroblasts after 48 and 72 hours. The expression level of TGF-β1 was detected by ELISA. Real-time PCR was used to detect the change level of TGF-β1 after compound angelica injection. \u0000 \u0000 \u0000Results \u0000MTS results showed that the proliferation of fibroblasts was inhibited in 20, 40, 80 mg/ml group (P<0.05); real-time PCR results showed that the transcription level of TGF-β1 in fibroblasts decreased in 10, 20, 40 mg/ml group compared with the control group 48 hours after the treatment of compound angelica injection (P<0.05). ELISA results showed that the expression of TGF-β1 was inhibited with the increase of drug concentration 48 hours after the treatment of compound angelica injection (P<0.05). \u0000 \u0000 \u0000Conclusion \u0000Compound angelica injection can inhibit the expression of TGF-β1 in human fibroblasts, suggesting that it can inhibit the proliferation of human fibroblasts, and the inhibition level is concentration-dependent after a certain period of time, which may affect the occurrence of tendon adhesion. \u0000 \u0000 \u0000Key words: \u0000Fibroblasts; Angelica sinensis; Tendon adhesion; TGF-β1","PeriodicalId":67383,"journal":{"name":"中华手外科杂志","volume":"35 1","pages":"293-296"},"PeriodicalIF":0.0,"publicationDate":"2019-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42796896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-10DOI: 10.3760/CMA.J.ISSN.1005-054X.2019.04.010
H. Qian, Guozhao Chen, Zongbao Liu, Xiaobo Zhu, Zhihao Cui, Feiwei Lu
Objective To explore the clinical efficacy of arthroscopy-assisted Sauve-Kapandji procedure in the treatment of distal radio-ulnar joint arthritis combined with extensor digitorum tendon rupture. Methods From September 2015 to December 2017, 8 patients with distal radio-ulnar joint arthritis combined with extensor digitorum tendon rupture were treated by arthroscopy-assisted Sauve-Kapandji procedure. The fractured tendons were repaired by tendon transplantation or braided suture of adjacent extensor digitorum tendons. Results All the patients were follow-up for 5 to 18 months with an average of 10 months. According to the upper extremity functional evaluation criteria issued by the Hand Surgery Society of the Chinese Medical Association, the results were rated as excellent in 5 cases, good in 2 cases and fair in 1 case. The pain of wrist joint in all the patients was relieved compared with that before operation. Conclusion The application of arthroscopy-assisted Sauve-Kapandji procedure in the treatment of distal radio-ulnar joint arthritis combined with extensor digitorum tendon rupture can obtain good clinical efficacy. Key words: Arthroscopes; Treatment outcome; Distal radio-ulnar joint arthritis; Extensor digitorum tendon rupture
{"title":"Arthroscopy-assisted Sauvé-Kapandji procedure for treatment of distal radio-ulnar joint arthritis combined with extensor digitorum tendon rupture","authors":"H. Qian, Guozhao Chen, Zongbao Liu, Xiaobo Zhu, Zhihao Cui, Feiwei Lu","doi":"10.3760/CMA.J.ISSN.1005-054X.2019.04.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-054X.2019.04.010","url":null,"abstract":"Objective \u0000To explore the clinical efficacy of arthroscopy-assisted Sauve-Kapandji procedure in the treatment of distal radio-ulnar joint arthritis combined with extensor digitorum tendon rupture. \u0000 \u0000 \u0000Methods \u0000From September 2015 to December 2017, 8 patients with distal radio-ulnar joint arthritis combined with extensor digitorum tendon rupture were treated by arthroscopy-assisted Sauve-Kapandji procedure. The fractured tendons were repaired by tendon transplantation or braided suture of adjacent extensor digitorum tendons. \u0000 \u0000 \u0000Results \u0000All the patients were follow-up for 5 to 18 months with an average of 10 months. According to the upper extremity functional evaluation criteria issued by the Hand Surgery Society of the Chinese Medical Association, the results were rated as excellent in 5 cases, good in 2 cases and fair in 1 case. The pain of wrist joint in all the patients was relieved compared with that before operation. \u0000 \u0000 \u0000Conclusion \u0000The application of arthroscopy-assisted Sauve-Kapandji procedure in the treatment of distal radio-ulnar joint arthritis combined with extensor digitorum tendon rupture can obtain good clinical efficacy. \u0000 \u0000 \u0000Key words: \u0000Arthroscopes; Treatment outcome; Distal radio-ulnar joint arthritis; Extensor digitorum tendon rupture","PeriodicalId":67383,"journal":{"name":"中华手外科杂志","volume":"35 1","pages":"264-266"},"PeriodicalIF":0.0,"publicationDate":"2019-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44079862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-10DOI: 10.3760/CMA.J.ISSN.1005-054X.2019.04.009
Liping Guo, J. Ju, Kai Wang, G. Jin, Quanwei Guo
Objective To report the clinical treatment and efficacy of replantation of finger degloving amputation in children. Methods From January 2010 to December 2017, 10 cases (12 fingers) of finger degloving amputation were performed replantation in children aged 11 months to 3 years old. The clinical features, surgical precautions and postoperative efficacy of the injuries were retrospectively analyzed. Results Postoperatively 10 fingers survived and 2 fingers died. The postoperative follow-up period was 6 to 12 months. Among them, 2 fingers had mild lateral deformity of distal segment development and 1 finger had hypertrophic scar contracture. The other fingers had good shape and functional recovery. According to the evaluation criteria of replantation function of severed fingers issued by Hand Surgery Society of Chinese Medical Association, the results were rated as excellent in 7 fingers, good in 2 fingers, and poor in 3 fingers. Conclusion The characteristics of finger degloving injury in children are various. Individualized treatment during and after operation can achieve better clinical efficacy. Key words: Child; Replantation; Degloving amputation; Treatment outcome
{"title":"Clinical analysis of replantation of finger degloving amputation in children","authors":"Liping Guo, J. Ju, Kai Wang, G. Jin, Quanwei Guo","doi":"10.3760/CMA.J.ISSN.1005-054X.2019.04.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-054X.2019.04.009","url":null,"abstract":"Objective \u0000To report the clinical treatment and efficacy of replantation of finger degloving amputation in children. \u0000 \u0000 \u0000Methods \u0000From January 2010 to December 2017, 10 cases (12 fingers) of finger degloving amputation were performed replantation in children aged 11 months to 3 years old. The clinical features, surgical precautions and postoperative efficacy of the injuries were retrospectively analyzed. \u0000 \u0000 \u0000Results \u0000Postoperatively 10 fingers survived and 2 fingers died. The postoperative follow-up period was 6 to 12 months. Among them, 2 fingers had mild lateral deformity of distal segment development and 1 finger had hypertrophic scar contracture. The other fingers had good shape and functional recovery. According to the evaluation criteria of replantation function of severed fingers issued by Hand Surgery Society of Chinese Medical Association, the results were rated as excellent in 7 fingers, good in 2 fingers, and poor in 3 fingers. \u0000 \u0000 \u0000Conclusion \u0000The characteristics of finger degloving injury in children are various. Individualized treatment during and after operation can achieve better clinical efficacy. \u0000 \u0000 \u0000Key words: \u0000Child; Replantation; Degloving amputation; Treatment outcome","PeriodicalId":67383,"journal":{"name":"中华手外科杂志","volume":"35 1","pages":"261-263"},"PeriodicalIF":0.0,"publicationDate":"2019-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45747272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-10DOI: 10.3760/CMA.J.ISSN.1005-054X.2019.04.008
Wentao Lv, J. Ju, Guodong Jiang, Xiaoqiang Tang, Mian Jing Wang, Hailiang Liu, Xiaosong Wang
Objective To explore the surgical method and clinical efficacy of tendon in situ suture in the replantation of avulsed severed finger. Methods From June 2014 to February 2018, 7 cases of severed finger with tendon pulled out from the abdomen were repaired and replanted by in situ embedding suture through the original tunnel. Results All the wounds achieved primary healing and the replantation of severed fingers was successful. There was no vascular crisis after operation. All the patients were follow-up for 6 to 20 months, with an average of 10 months. The replanted finger has good blood supply, good appearance, full belly, and satisfactory function of flexion, extension and opposition. The two-point discrimination of finger pulp was 8 to 14 mm. According to the evaluation criteria of replantation function of severed fingers issued by Hand Surgery Society of Chinese Medical Association, the results were rated as excellent in 5 fingers, good in 1 finger, and fair in 1 finger. Only linear scars were left on the forearm, and wrist flexion and extension were not limited. Conclusion The tendon of avulsed severed finger can be repaired by suture in situ via the original tunnel. The superficial vein and cutaneous nerve can also be harvested from the same incision of forearm to repair the defect of digital artery and nerve. Satisfactory results can be obtained after operation. Key words: Finger injuries; Replantation; Avulsion; Tendon; In situ suture
{"title":"Application of tendon suture in situ in replantation of avulsed severed finger","authors":"Wentao Lv, J. Ju, Guodong Jiang, Xiaoqiang Tang, Mian Jing Wang, Hailiang Liu, Xiaosong Wang","doi":"10.3760/CMA.J.ISSN.1005-054X.2019.04.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-054X.2019.04.008","url":null,"abstract":"Objective \u0000To explore the surgical method and clinical efficacy of tendon in situ suture in the replantation of avulsed severed finger. \u0000 \u0000 \u0000Methods \u0000From June 2014 to February 2018, 7 cases of severed finger with tendon pulled out from the abdomen were repaired and replanted by in situ embedding suture through the original tunnel. \u0000 \u0000 \u0000Results \u0000All the wounds achieved primary healing and the replantation of severed fingers was successful. There was no vascular crisis after operation. All the patients were follow-up for 6 to 20 months, with an average of 10 months. The replanted finger has good blood supply, good appearance, full belly, and satisfactory function of flexion, extension and opposition. The two-point discrimination of finger pulp was 8 to 14 mm. According to the evaluation criteria of replantation function of severed fingers issued by Hand Surgery Society of Chinese Medical Association, the results were rated as excellent in 5 fingers, good in 1 finger, and fair in 1 finger. Only linear scars were left on the forearm, and wrist flexion and extension were not limited. \u0000 \u0000 \u0000Conclusion \u0000The tendon of avulsed severed finger can be repaired by suture in situ via the original tunnel. The superficial vein and cutaneous nerve can also be harvested from the same incision of forearm to repair the defect of digital artery and nerve. Satisfactory results can be obtained after operation. \u0000 \u0000 \u0000Key words: \u0000Finger injuries; Replantation; Avulsion; Tendon; In situ suture","PeriodicalId":67383,"journal":{"name":"中华手外科杂志","volume":"35 1","pages":"258-260"},"PeriodicalIF":0.0,"publicationDate":"2019-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46576919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-08-10DOI: 10.3760/CMA.J.ISSN.1005-054X.2019.04.002
W. Feng, Danmou Xing, D. Ren, Yan Chen, Huan Wang, Zhihong Xiao, Ming Zhang, Zheng-ren Peng
Objective To introduce the surgical technique and clinical efficacy of Reading man flap for repair of the wound of donor site at the dorsum of the finger. Methods From February 2016 to August 2018, 9 cases (9 fingers) of fingertip defects were treated with reverse dorsal digital island flap of the same finger. The donor site of dorsal digital flaps was repaired with Reading man flap. After repair of fingertip defects, the defect area of dorsal digital donor site ranged from 2.0 cm×1.3 cm to 2.5 cm×1.6 cm. Results All the flaps survived uneventfully. The average hospitalization time was 10 days. The follow-up time was 3 to 9 months. The texture, color, plumpness and elasticity of the dorsal digital donor site were good. No tendon adhesion, interphalangeal joint and metacarpophalangeal joint stiffness occurred. All the patients were satisfied with the appearance and function of the injured fingers. Conclusion The repair of the dorsal digital donor site with Reading man flap takes into account both appearance and durability, which is beneficial to the early rehabilitation of injured finger and less damage to donor site. The method of operation is safe and simple. It is an improvement on the repair of the donor site of the reverse dorsal digital island flap of the same finger. Key words: Finger injuries; Surgical flaps; Reading man flap; Flap donor site
{"title":"Clinical application of Reading man flap for repair of the wound of donor site at the dorsum of the finger","authors":"W. Feng, Danmou Xing, D. Ren, Yan Chen, Huan Wang, Zhihong Xiao, Ming Zhang, Zheng-ren Peng","doi":"10.3760/CMA.J.ISSN.1005-054X.2019.04.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1005-054X.2019.04.002","url":null,"abstract":"Objective \u0000To introduce the surgical technique and clinical efficacy of Reading man flap for repair of the wound of donor site at the dorsum of the finger. \u0000 \u0000 \u0000Methods \u0000From February 2016 to August 2018, 9 cases (9 fingers) of fingertip defects were treated with reverse dorsal digital island flap of the same finger. The donor site of dorsal digital flaps was repaired with Reading man flap. After repair of fingertip defects, the defect area of dorsal digital donor site ranged from 2.0 cm×1.3 cm to 2.5 cm×1.6 cm. \u0000 \u0000 \u0000Results \u0000All the flaps survived uneventfully. The average hospitalization time was 10 days. The follow-up time was 3 to 9 months. The texture, color, plumpness and elasticity of the dorsal digital donor site were good. No tendon adhesion, interphalangeal joint and metacarpophalangeal joint stiffness occurred. All the patients were satisfied with the appearance and function of the injured fingers. \u0000 \u0000 \u0000Conclusion \u0000The repair of the dorsal digital donor site with Reading man flap takes into account both appearance and durability, which is beneficial to the early rehabilitation of injured finger and less damage to donor site. The method of operation is safe and simple. It is an improvement on the repair of the donor site of the reverse dorsal digital island flap of the same finger. \u0000 \u0000 \u0000Key words: \u0000Finger injuries; Surgical flaps; Reading man flap; Flap donor site","PeriodicalId":67383,"journal":{"name":"中华手外科杂志","volume":"35 1","pages":"244-246"},"PeriodicalIF":0.0,"publicationDate":"2019-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46026667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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