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Population-based incidence and demographic patterns of traumatic joint dislocations in children and adolescents. 儿童和青少年创伤性关节脱位的人群发生率和人口统计学模式。
IF 2.4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-29 DOI: 10.2340/17453674.2025.44880
William J Söderling, Ilkka J Helenius, Petra M Grahn, Mika V J Gissler, Topi A Laaksonen, Matti M Ahonen

Background and purpose:  Limited population-based data is available concerning traumatic joint dislocations in children and adolescents. We aimed to determine the incidence, typical locations, and demographic patterns of joint dislocations in a pediatric population.

Methods:  This retrospective, population-based study analyzed pediatric joint dislocations in the Helsinki University Hospital catchment area from 2009 to 2021. Data was retrieved from electronic health records using ICD-10 codes and radiological keywords. Primary radiographs were reviewed to confirm diagnoses. Incidences were calculated using population data, and trends were analyzed by age, sex, and dislocation site. 2,741 traumatic dislocations were included.

Results:  The overall annual incidence of joint dislocations was 69 per 100,000 children, with a higher incidence in boys than in girls (72 vs 66 per 100,000, odds ratio 1.1, 95% confidence interval 1.02-1.2). The peak incidence occurred at 16 years of age for boys and 15 years of age for girls. Patellar (49%), elbow (19%), finger (12%), and glenohumeral (10%) dislocations accounted for 90% of cases with respective mean incidence; 35, 13, 8.4 and 7.1 per 100,000.

Conclusion:  The annual incidence averaged 69 per 100,000 children. Joint dislocations in children predominantly affect the patellar, elbow, finger, and glenohumeral joints, with adolescence being the most vulnerable period.

背景和目的:关于儿童和青少年创伤性关节脱位的人群数据有限。我们的目的是确定儿童关节脱位的发生率、典型部位和人口统计学模式。方法:这项基于人群的回顾性研究分析了2009年至2021年赫尔辛基大学医院集水区的儿童关节脱位。使用ICD-10代码和放射学关键词从电子健康记录中检索数据。回顾原始x线片以确认诊断。使用人口数据计算发病率,并按年龄、性别和脱位地点分析趋势。包括2741例外伤性脱位。结果:关节脱位的年总发病率为69 / 10万儿童,男孩的发病率高于女孩(72 vs 66 / 10万,优势比1.1,95%可信区间1.02-1.2)。发病率高峰发生在男孩16岁和女孩15岁。髌骨脱位(49%)、肘关节脱位(19%)、手指脱位(12%)和肩关节脱位(10%)分别占平均发生率的90%;每10万人35、13、8.4和7.1人。结论:年平均发病率为69 / 10万。儿童关节脱位主要影响髌骨、肘关节、手指和肩关节,青春期是最脆弱的时期。
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引用次数: 0
Radiostereometric analysis for evaluating inducible fracture micromotion: a scoping review. 评价诱导断裂微运动的放射立体分析:范围综述。
IF 2.4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-27 DOI: 10.2340/17453674.2025.44897
Michaela Manalili Hansen, Mohammad Laith Ballo, Stephan Maximillian Röhrl

Background and purpose:  Reliable assessment of fracture healing remains a clinical challenge as radiographs and clinical examination provide only indirect information. Inducible fracture micromotion, defined as fragment displacement under load, may offer a more direct surrogate for healing. Radiostereometric analysis (RSA) can measure micromotion with high precision, but its clinical use for fracture assessment remains limited and heterogeneous. This scoping review aimed to map the existing literature on RSA for inducible fracture micromotion and summarize methodological approaches to guide future research.

Methods:  We systematically searched Medline, Embase, and Scopus. Clinical studies applying RSA to assess inducible fracture micromotion were eligible. 2 reviewers independently screened and extracted data on study design, patient population, fracture location, loading protocols, thresholds for motion, and outcomes.

Results:  7 clinical studies were included, comprising feasibility studies, prospective cohorts, and 1 imaging study. Sample sizes ranged from 6 to 16 patients, with fractures of the distal radius, femur, proximal tibia, and pelvis. All studies required intraoperative implantation of tantalum markers. Most applied differentially loaded RSA, typically comparing unloaded and loaded conditions using weightbearing platforms, force plates, or voluntary grip dynamometry. Despite varied protocols and small, single-center designs, RSA consistently detected small-scale inducible motion and, in some studies, distinguished union from non-union.

Conclusion:  This scoping review identified 7 clinical studies using RSA to assess inducible fracture micromotion, with heterogeneous methods across fracture types. These findings may guide the development of standardized approaches and support future research on RSA in fracture healing.

背景和目的:骨折愈合的可靠评估仍然是一个临床挑战,因为x线片和临床检查只能提供间接信息。诱导性骨折微运动,定义为碎片在载荷下的位移,可能为愈合提供更直接的替代。放射立体分析(RSA)可以高精度地测量微运动,但其在骨折评估中的临床应用仍然有限且不均匀。本文综述了RSA诱导断裂微运动的现有文献,并总结了指导未来研究的方法。方法:系统地检索Medline、Embase和Scopus。应用RSA评估诱导性骨折微动的临床研究符合条件。2位审稿人独立筛选和提取研究设计、患者群体、骨折位置、加载方案、运动阈值和结果的数据。结果:纳入7项临床研究,包括可行性研究、前瞻性队列研究和1项影像学研究。样本大小从6到16例患者,桡骨远端、股骨、胫骨近端和骨盆骨折。所有的研究都需要术中植入钽标记物。大多数应用差分加载RSA,通常使用承重平台、力板或自动抓地测力法比较卸载和加载条件。尽管有不同的协议和小的单中心设计,RSA一致地检测到小规模的诱导运动,并在一些研究中区分了愈合和不愈合。结论:本综述确定了7项使用RSA评估可诱导骨折微动的临床研究,不同骨折类型的方法不同。这些发现可能会指导标准化方法的发展,并支持RSA在骨折愈合中的未来研究。
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引用次数: 0
Editorial: Challenges in global advancement of robotic surgery. 社论:机器人手术在全球发展中的挑战。
IF 2.4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-27 DOI: 10.2340/17453674.2025.44879
Birger C Forsberg, Martin Gerdin Wärnberg
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引用次数: 0
Chronic pain after primary total and medial unicompartmental knee arthroplasty for osteoarthritis: a Danish nationwide cross-sectional survey. 原发性全单室和内侧单室膝关节置换术治疗骨关节炎后的慢性疼痛:丹麦全国横断面调查。
IF 2.4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-27 DOI: 10.2340/17453674.2025.44898
Jens Laigaard, Saber M Aljuboori, Lone Nikolajsen, Ole Mathiesen, Troels H Lunn, Martin Lindberg-Larsen, Søren Overgaard

Background and purpose:  Contemporary data on the risk of chronic pain after total knee arthroplasty (TKA) and unicompartmental knee arthroplasty (UKA) is limited. Therefore, we aimed to investigate the incidence of chronic pain, pain characteristics, patterns of analgesic use, patient satisfaction, and willingness to undergo the same surgery again, 1 year after primary TKA and UKA for osteoarthritis.

Methods:  We conducted a nationwide online survey among unselected patients who underwent primary TKA or medial UKA for primary osteoarthritis in Denmark. At 1 year postoperatively, we assessed the incidence of moderate to severe pain (≥ 4 on the 0-10 numerical rating scale), frequency of pain, pain interference with everyday life, the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain domain, the Douleur Neuropathique 4 interview (DN4i), use of analgesics, satisfaction, and willingness to undergo the same surgery again.

Results:  We sent survey invitations to 2,580 TKA patients and 1,007 UKA patients who underwent surgery in 2022. Of the 70% TKA respondents, 25% had moderate to severe chronic pain, 82% were satisfied/very satisfied with the result of surgery, and 86% indicated that they would choose to undergo surgery again. Of the 75% UKA respondents, 23% had moderate to severe chronic pain, 86% were satisfied/very satisfied, and 88% would undergo the same surgery again.

Conclusion: In Denmark, 25% of TKA patients and 23% of medial UKA patients experienced moderate to severe knee pain after 1 year. These numbers were higher than most previous estimates. Most patients were satisfied with the result of surgery and would undergo the same surgery again.

背景和目的:目前关于全膝关节置换术(TKA)和单室膝关节置换术(UKA)后慢性疼痛风险的数据有限。因此,我们的目的是调查慢性疼痛的发生率,疼痛特征,镇痛药使用模式,患者满意度,以及在骨关节炎原发性TKA和UKA后1年再次接受相同手术的意愿。方法:我们对丹麦因原发性骨关节炎而接受原发性TKA或内侧UKA的未选择患者进行了全国范围的在线调查。术后1年,我们评估了中度至重度疼痛的发生率(0-10数值评分≥4)、疼痛频率、疼痛对日常生活的干扰、西安大略和麦克马斯特大学骨关节炎指数(WOMAC)疼痛域、Douleur神经病变4访谈(DN4i)、镇痛药的使用、满意度和再次接受相同手术的意愿。结果:我们向2022年接受手术的2580例TKA患者和1007例UKA患者发送了调查邀请。在70%的TKA受访者中,25%的人有中度至重度慢性疼痛,82%的人对手术结果满意/非常满意,86%的人表示会选择再次接受手术。在75%的UKA受访者中,23%的人患有中度至重度慢性疼痛,86%的人满意/非常满意,88%的人会再次接受相同的手术。结论:在丹麦,25%的TKA患者和23%的内侧UKA患者在1年后出现中度至重度膝关节疼痛。这些数字高于以前的大多数估计。大多数患者对手术结果满意,并愿意再次接受相同的手术。
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引用次数: 0
Trends and predictors of cemented fixation in arthroplasty for patients with a hip fracture: a Canadian Joint Replacement Registry study. 髋部骨折患者关节置换术中骨水泥固定的趋势和预测因素:一项加拿大关节置换术注册研究。
IF 2.4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-27 DOI: 10.2340/17453674.2025.44751
Christiaan H Righolt, Colton Poitras, Gavin C A Wood, Eric R Bohm

Background and purpose: Cemented fixation is widely recommended during arthroplasty for hip fractures, yet it has not been universally adopted by all surgeons and hospitals. We aimed to identify which factors were associated with a higher likelihood of cemented fixation.

Methods: We identified patients ≥ 55 years old with hip fractures treated with primary arthroplasty in Canada between 2012 and 2022. We determined fixation method along with several surgeon and hospital characteristics from the Canadian Joint Replacement Registry and other Canadian databases. We used logistic regression to estimate the odds ratios (ORs) of the association between these covariates and cemented fixation.

Results: We identified 65,823 patients who underwent arthroplasty for hip fractures. The proportion of cases with cemented fixation for hemiarthroplasty increased by 30 percentage points over the study period; the proportion for total hip arthroplasty (THA) remained relatively stable. High-volume hospitals (≥ 500 annual hip arthroplasties with ≥ 25% of these for fractures) were least likely to cement, OR = 0.30; 95% confidence interval (CI) 0.27-0.34 vs low-volume hospitals (< 500 cases/< 25% for fractures). High volume surgeons (≥ 50 hips/year, ≥ 16/year for fractures) had an OR of 0.80 (CI 0.75-0.84) compared with < 50 hips/year surgeons. Teaching hospitals were more likely to cement, OR = 1.16 (CI 1.10-1.22). The OR of cemented fixation for hemiarthroplasty (vs THA) rose from 1.13 (CI 0.99-1.29) at the start of the study period to 2.17 (CI 2.02-2.33) at the end.

Conclusion: The use of cemented fixation in hip fracture arthroplasty has increased across Canada over the last decade. However, surgeons and hospitals that treat more hip fracture patients are less likely to cement. The proportion of cemented fixation increases with patient age. Cement use is more common in hemiarthroplasty than in THA.

背景和目的:骨水泥固定被广泛推荐用于髋部骨折的关节置换术,但尚未被所有外科医生和医院普遍采用。我们的目的是确定哪些因素与较高的骨水泥固定可能性相关。方法:我们选取了2012年至2022年间在加拿大接受初级关节置换术治疗的≥55岁髋部骨折患者。我们根据来自加拿大关节置换登记和其他加拿大数据库的几个外科医生和医院特征确定了固定方法。我们使用逻辑回归来估计这些协变量与骨水泥固定之间关联的比值比(ORs)。结果:65,823例髋部骨折患者接受了髋关节置换术。在研究期间,半关节置换术中使用骨水泥固定的病例比例增加了30个百分点;全髋关节置换术的比例保持相对稳定。大容量医院(每年≥500例髋关节置换术,其中≥25%为骨折)最不可能发生骨水泥,OR = 0.30;95%置信区间(CI) 0.27-0.34 vs小容量医院(< 500例/< 25%骨折)。大容量外科医生(≥50髋/年,骨折≥16髋/年)与< 50髋/年的外科医生相比,OR为0.80 (CI 0.75-0.84)。教学医院更容易发生骨水泥,OR = 1.16 (CI 1.10-1.22)。半关节置换术中骨水泥固定(vs THA)的OR从研究开始时的1.13 (CI 0.99-1.29)上升到研究结束时的2.17 (CI 2.02-2.33)。结论:在过去的十年中,加拿大髋部骨折置换术中骨水泥固定的使用有所增加。然而,治疗更多髋部骨折患者的外科医生和医院不太可能使用骨水泥。骨水泥固定的比例随着患者年龄的增长而增加。骨水泥在半关节置换术中比在全髋关节置换术中更常见。
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引用次数: 0
Cost-effectiveness analysis of locking nail compared with locking plate for displaced 3- and 4-part proximal humerus fractures: a secondary analysis of a randomized trial comparing the Multiloc nail and PHILOS plate. 锁定钉与锁定钢板治疗移位的肱骨近端3部和4部骨折的成本-效果分析:一项比较Multiloc钉和PHILOS钢板的随机试验的二次分析。
IF 2.4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-27 DOI: 10.2340/17453674.2025.44881
Annette Konstanse Bordewich Wikerøy, Per-Henrik Randsborg, Eline Aas, Hendrik Frølich Stange Fuglesang, Rune Bruhn Jakobsen Jakobsen

Background and purpose:  Previous studies show no clear difference in functional outcomes between locking nails and plates for proximal humerus fractures (PHFs). Economic evaluations provide valuable insights into cost-effectiveness to guide healthcare decisions. We aimed to conduct a cost-effectiveness analysis based on a semidouble-blinded randomized controlled trial comparing nailing and plating for displaced 3- and 4-part PHFs with 2-year follow-up.

Methods:  79 patients with displaced 3- or 4-part PHFs were randomized to undergo open reduction and internal fixation using either a nail or a plate. Patients were followed for 2 years, with costs tracked for the index surgery, hospital stay, additional healthcare services, and secondary procedures. Quality-adjusted life years (QALYs) were calculated using EQ-5D, and incremental cost-effectiveness ratios (ICERs) were used to compare treatments.

Results:  38 patients in each group were eligible for analysis. Mean total costs were €21,654 (standard deviation [SD] 10,448) for nails and €16,374 (SD 3,886) for plates, with a mean difference of €5,296 (95% confidence interval [CI] 1,989-8,603). Extra costs for reoperations and other non-regular follow-ups were €3,746 (SD 10,448) for nails and €265, (SD 1,217) for plates, resulting in a mean difference of €3,480 (CI -868 to 7,829) extra costs for nails. The mean QALY showed no statistical difference between groups of 0.09 (CI -0.003 to 0.17) (1.65 in the nail group and 1.74 in the plate group).

Conclusion:  Plates were more cost-effective compared with nails but did not result in a statistically significant difference in QALY.

背景和目的:先前的研究显示锁定钉和钢板治疗肱骨近端骨折(phf)的功能结果没有明显差异。经济评估为成本效益提供有价值的见解,以指导医疗保健决策。我们的目的是在一项半双盲随机对照试验的基础上进行成本-效果分析,该试验比较钉钉和电镀治疗移位的3部和4部phf,随访2年。方法:79例移位的3部分或4部分phf患者随机接受切开复位并使用钉子或钢板内固定。对患者进行了2年的随访,追踪了主要手术、住院时间、额外医疗服务和二次手术的费用。使用EQ-5D计算质量调整生命年(QALYs),并使用增量成本-效果比(ICERs)比较治疗。结果:每组38例患者符合分析条件。钉子的平均总成本为21,654欧元(标准差[SD] 10,448),钢板的平均总成本为16,374欧元(标准差[SD] 3,886),平均差异为5,296欧元(95%置信区间[CI] 1989 -8,603)。再手术和其他不定期随访的额外费用为钉子3,746欧元(SD 10,448),钢板为265欧元(SD 1,217),导致钉子的额外费用平均相差3,480欧元(CI -868至7,829)。平均质量aly组间差异无统计学意义,为0.09 (CI -0.003 ~ 0.17)(钉组1.65,钢板组1.74)。结论:钢板比钉更具成本效益,但QALY差异无统计学意义。
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引用次数: 0
Distal chevron osteotomies enhance patient-reported outcomes for all severity grades of hallux valgus: a cohort study. 远端拇趾截骨术提高了所有严重程度的拇外翻患者报告的结果:一项队列研究。
IF 2.4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-16 DOI: 10.2340/17453674.2025.44750
Cyrus D Brodén, Ann-Charlott Söderpalm, Eva Tengman, Nils P Hailer, Maria C Cöster

Background and purpose:  There is limited data on the functional outcome after hallux valgus (HV) surgery. Our study aims to assess 1-year postoperative patient-reported outcomes (PROMs) after a chevron osteotomy (CO) for 3 severity levels, the number of additional surgical interventions during the index procedure, and the association between the presence or absence of internal fixation and PROMs.

Methods:  This is a prospective cohort from the Swedish register for foot and ankle surgery (Swefoot), including patients treated with primary CO between 2014 and 2021. HV deformities were classified into 3 severity grades. Preoperative demographic data, additional surgical procedures, and PROMs (Self-reported Foot and Ankle Score [SEFAS] and the EuroQol 5-dimensional 3-level scale [EQ-5D-3L]) were collected both pre- and 1 year post-surgery.

Results:  The study included 2,259 HV feet (2,123 patients, mean age 55 (range 15-90) years, 83% women) The mean SEFAS score increased by 11 (95% confidence interval [CI] 9.8-11.8) points from the pre-surgery assessment to the 1-year post-surgery follow-up for the mild HV group, by 9 (CI 9.0-10.0) for the moderate, and by 9 (CI 7.5-9.8) for the severe group. EQ-5D-3L also improved in all 3 groups. For all 3 HV grades, patients treated with fixation demonstrated no statistically significant improvements in SEFAS scores compared with those without fixation.

Conclusion:  Distal chevron osteotomy improved 1-year patient-reported outcomes across all grades of hallux valgus. Improvements were observed both with and without internal fixation. In more severe cases, additional procedures such as Akin osteotomy and distal soft tissue release were more commonly performed.

背景和目的:关于拇外翻手术后功能结局的资料有限。我们的研究旨在评估3种严重程度的chevron osteotomy (CO)术后1年患者报告的预后(PROMs),在指数手术期间额外手术干预的次数,以及是否存在内固定与PROMs之间的关系。方法:这是一项来自瑞典足部和踝关节手术(Swefoot)登记的前瞻性队列研究,包括2014年至2021年间接受原发性CO治疗的患者。HV畸形分为3个严重等级。术前和术后1年收集患者的人口统计数据、附加手术程序和PROMs(自我报告足踝评分[SEFAS]和EuroQol 5维3级量表[EQ-5D-3L])。结果:该研究纳入2259例HV足(2123例患者,平均年龄为55岁(15-90岁),83%为女性)。从术前评估到术后1年随访,轻度HV组平均SEFAS评分增加了11分(95%可信区间[CI] 9.8-11.8),中度HV组平均SEFAS评分增加了9分(CI 9.0-10.0),重度HV组平均SEFAS评分增加了9分(CI 7.5-9.8)。三组患者的EQ-5D-3L均有改善。对于所有3个HV级别,接受固定治疗的患者与未接受固定治疗的患者相比,SEFAS评分没有统计学上的显著改善。结论:远端拇趾截骨术改善了所有级别拇外翻患者报告的1年预后。有无内固定均可观察到改善。在更严重的病例中,通常会进行额外的手术,如Akin截骨术和远端软组织释放。
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引用次数: 0
An Acta Orthopaedica educational article: Weightbearing assessment to guide nonoperative treatment of lateral malleolar fractures: the paradigm change. 一篇骨科学报教育性文章:负重评估指导外踝骨折非手术治疗:范式改变。
IF 2.4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-16 DOI: 10.2340/17453674.2025.44878
Emilia Möller Rydberg, Kristian Pilskog, Harri Pakarinen, Per Henrik Randsborg, Charles L Saltzman, Marius Molund

The goal of this Acta Orthopaedica educational article is to provide an update on how to evaluate lateral malleolar ankle fractures at the level of the syndesmosis and to guide clinicians in selecting the most appropriate treatment method. We aim to clarify the indications for non-surgical treatment and to provide clinicians with an evidence-based approach to decision-making in these frequently encountered injuries. The authors introduce the concept of "congruent on weightbearing" in contrast to the historical thinking of ankle fractures as stable or unstable. We further elaborate on how this thinking should be the basis in the decision-making regarding treatment method to safely differentiate fractures that will heal uneventfully without surgical intervention from those that need internal reduction and stabilization. As long as crucial parts of the deltoid ligament are intact, lateral malleolar ankle fractures at the level of the syndesmosis maintain, or regain, joint congruency under weightbearing. Ankle fractures that stay congruent under weightbearing often heal uneventfully and can be safely treated without surgery. Furthermore, research has shown that early weightbearing and short immobilization periods are beneficial for patient recovery without an increase in complication rates.

这篇骨科学报教育性文章的目的是提供关于如何在韧带联合水平评估外踝踝骨折的最新信息,并指导临床医生选择最合适的治疗方法。我们的目的是澄清非手术治疗的适应症,并为临床医生提供一个基于证据的方法来决策这些经常遇到的伤害。作者介绍了“负重一致”的概念,与以往认为踝关节骨折为稳定或不稳定的观念形成对比。我们进一步阐述了如何将这种想法作为决策治疗方法的基础,以安全区分那些无需手术干预即可平静愈合的骨折和那些需要内部复位和稳定的骨折。只要三角韧带的关键部分完好无损,外踝关节韧带联合水平的骨折在负重作用下保持或恢复关节一致性。在负重下保持一致的踝关节骨折通常愈合得很顺利,无需手术即可安全治疗。此外,研究表明,早期负重和短固定时间有利于患者康复,而不会增加并发症的发生率。
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引用次数: 0
Nationwide incidence of lateral malleolar fracture surgery across 6 European countries: has recent evidence changed clinical practice? 6个欧洲国家外踝骨折手术的全国发生率:最近的证据是否改变了临床实践?
IF 2.4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-10 DOI: 10.2340/17453674.2025.44797
Ville Ponkilainen, Thomas Ibounig, Tim Jones, Aleksi Reito, Tom J Crijns, Michael Whitehouse, Li Felländer-Tsai, Cyrill Suter, Lasse Rämö, Teppo L N Järvinen

Background and purpose:  Increased use of weightbearing radiographs to assess ankle mortise stability have suggested that most lateral malleolar fractures with a congruent mortise on initial radiographs can successfully be treated nonoperatively. We aimed to evaluate trends in the surgical management of isolated lateral malleolus fractures across Austria, England, Finland, Germany, Sweden, and Switzerland from 2013 to 2022 Methods: We performed a multi-register study to document the annual incidence of operative treatment for isolated lateral malleolus fractures through procedure codes across 6 European countries between 2013 and 2022. The annual incidence of operative treatment was calculated by dividing the total number of procedures per year by the year- and age-matched population based on publicly available demographics data.

Results:  Across the 6 studied European countries, the incidence of surgery for lateral malleolar fracture varied 6-fold between the country with highest (Germany) and lowest (England) incidences; Germany: 37 (95% confidence interval [CI] 37-38) per 105; Switzerland: 34 (CI 32-35) per 105, Austria: 27 (CI 26-28) per 105, Finland: 17 (CI 16-18) per 105, Sweden: 8 (CI 7-9) per 105, and England: 6 (CI 6-7) per 105 in 2021. Over the 10-year study period, the incidence of surgery for lateral malleolar fractures declined notably in Sweden (-29%), Finland (-26%), England (-20%), and Switzerland (-14%), but remained stable in Germany and Austria.

Conclusion:  The incidence of surgery for lateral malleolar fracture varied 6-fold across 6 studied European countries. Reductions of approximately 20-30% were observed in England, Sweden, and Finland (countries with the lowest baseline rates), while in Germany and Austria (countries with higher baseline rates), the incidence of surgery remained stable over the 10-year observation period.

背景和目的:越来越多地使用负重x线片来评估踝关节榫眼的稳定性,这表明大多数外踝骨折在初始x线片上具有一致的榫眼,可以成功地非手术治疗。我们旨在评估2013年至2022年奥地利、英国、芬兰、德国、瑞典和瑞士孤立性外踝骨折手术治疗的趋势。方法:我们进行了一项多登记研究,通过2013年至2022年6个欧洲国家的手术规范记录了孤立性外踝骨折的年发病率。手术治疗的年发生率是通过将每年的手术总数除以基于公开的人口统计数据的年龄匹配的人口来计算的。结果:在研究的6个欧洲国家中,外踝骨折的手术发生率在发生率最高的国家(德国)和发生率最低的国家(英国)之间变化了6倍;德国:37 / 105(95%置信区间[CI] 37-38);到2021年,瑞士:每105人34人(CI 32-35),奥地利:每105人27人(CI 26-28),芬兰:每105人17人(CI 16-18),瑞典:每105人8人(CI 7-9),英国:每105人6人(CI 6-7)。在10年的研究期间,外踝骨折的手术发生率在瑞典(-29%)、芬兰(-26%)、英国(-20%)和瑞士(-14%)显著下降,但在德国和奥地利保持稳定。结论:在研究的6个欧洲国家中,外踝骨折的手术发生率相差6倍。在英国、瑞典和芬兰(基线率最低的国家),手术发生率降低了约20-30%,而在德国和奥地利(基线率较高的国家),手术发生率在10年观察期内保持稳定。
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引用次数: 0
10-year trends in benzodiazepine, opioid, and concurrent use in hip and knee arthroplasty: a nationwide cohort study from the Netherlands. 苯二氮卓类药物、阿片类药物以及髋关节和膝关节置换术同时使用的10年趋势:来自荷兰的一项全国性队列研究
IF 2.4 2区 医学 Q1 ORTHOPEDICS Pub Date : 2025-10-10 DOI: 10.2340/17453674.2025.44755
Manuela Yepes-Calderón, Rob G H H Nelissen, Marcel L Bouvy, Frits R Rosendaal, Liza N Van Steenbergen, Albert Dahan, Maaike G J Gademan

Background and purpose: Concurrent benzodiazepine-opioid use is discouraged. We aimed to examine trajectories of benzodiazepine, opioid, and concurrent use following hip and knee arthroplasties for osteoarthritis (HA-OA, KA) and hip arthroplasty for fracture (HA-fracture).

Methods: In this nationwide cohort study, the Dutch Arthroplasty Register (LROI) was linked to the Dutch Foundation for Pharmaceutical Statistics (SFK). We evaluated the proportion of patients with ≥ 1 medication dispensation in the year pre- and post-procedure and the prescribing physicians. Concurrent use was defined as ≥ 7 days overlap of benzodiazepine and opioid exposure.

Results: We included 109,238 HA-OA, 17,464 HA fracture, and 113,306 KA. Between 2013 and 2021, the risk difference of postoperative benzodiazepine use was -7.2% (95% confidence interval [CI] -8.1 to -6.2%), while postoperative opioid use increased by 29.7% (CI 28.5-30.8%). Among HA-OA, from 2013 (4,391 arthroplasties) to 2021 (12,905 arthroplasties), the percentage of preoperative benzodiazepine users went from 18% to 13%, and postoperative from 23% to 14%. In contrast, preoperative opioid use changed from 25% to 33% and postoperative from 36% to 69%, In 2021, 6% of HA-OA, 11% of HA fracture, and 9% of KA received a concurrent dispensation in the first post-procedure year, predominantly in the first quarter. Orthopedic surgeons prescribed 29% (~18,732 prescriptions) of initial concurrent dispensations; subsequent prescriptions were mainly from general practitioners.

Conclusion: From 2013-2022 in the Netherlands, benzodiazepine use decreased while opioid use increased among arthroplasty patients. Concurrent use remained frequent, despite safety recommendations against co-prescribing.

背景和目的:不鼓励同时使用苯二氮卓类药物和阿片类药物。我们的目的是研究骨关节炎(HA-OA, KA)和骨折(ha -骨折)髋关节置换术后苯二氮卓类药物、阿片类药物和同时使用的轨迹。方法:在这项全国性队列研究中,荷兰关节成形术登记(LROI)与荷兰药物统计基金会(SFK)相关联。我们评估了术前、术后一年有≥1种药物分配的患者比例以及开处方的医生。同时使用定义为苯二氮卓类药物和阿片类药物暴露重叠≥7天。结果:我们纳入了109,238例HA- oa, 17,464例HA骨折和113,306例KA。2013年至2021年,术后苯二氮卓类药物使用的风险差异为-7.2%(95%置信区间[CI] -8.1至-6.2%),而术后阿片类药物使用的风险差异为29.7% (CI 28.5-30.8%)。在HA-OA中,从2013年(4391例关节置换术)到2021年(12905例关节置换术),术前苯二氮卓类药物使用者的比例从18%上升到13%,术后从23%上升到14%。相比之下,术前阿片类药物的使用从25%增加到33%,术后从36%增加到69%。2021年,6%的HA- oa、11%的HA骨折和9%的KA在手术后的第一年同时获得了配药,主要是在第一季度。骨科医生的处方占首次并发配药的29%(约18,732张);后续处方主要来自全科医生。结论:2013-2022年,荷兰关节置换术患者苯二氮卓类药物的使用减少,阿片类药物的使用增加。同时使用仍然频繁,尽管安全建议反对联合处方。
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Acta Orthopaedica
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