Pub Date : 2024-08-05DOI: 10.2340/actadv.v104.40731
Dan Danielsson
{"title":"Commentary on: The Syphilis Pandemic Prior to Penicillin: Origin, Health Issues, Cultural Representation, and Ethical Challenges.","authors":"Dan Danielsson","doi":"10.2340/actadv.v104.40731","DOIUrl":"10.2340/actadv.v104.40731","url":null,"abstract":"","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11318503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141888131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-05DOI: 10.2340/actadv.v104.40677
Wei Jiang, Jianru Chen, Nan Li, Xueyong Wang, Chunying Li
{"title":"Depression, Anxiety and Suicidal Ideation in Prurigo Nodularis: A Systematic Review and Meta-analysis.","authors":"Wei Jiang, Jianru Chen, Nan Li, Xueyong Wang, Chunying Li","doi":"10.2340/actadv.v104.40677","DOIUrl":"10.2340/actadv.v104.40677","url":null,"abstract":"","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11318501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141888132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-05DOI: 10.2340/actadv.v104.40193
Xue-Min Wang, Ye-Qiang Liu, Bin Li, Ming Li, Yan Peng, Wen-Cheng Jiang
{"title":"Single-system Langerhans Cell Histiocytosis with Skin Ulcers as the Initial Presentation.","authors":"Xue-Min Wang, Ye-Qiang Liu, Bin Li, Ming Li, Yan Peng, Wen-Cheng Jiang","doi":"10.2340/actadv.v104.40193","DOIUrl":"10.2340/actadv.v104.40193","url":null,"abstract":"","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11318502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141888133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The pattern of itching in patients with atopic dermatitis has not been systematically studied. Therefore, this study aimed to assess the pattern of itching in adults with atopic dermatitis using questionnaires to assess for a circadian rhythm of itching in participating patients at a single institution (n = 241). A self-report questionnaire was used to assess circadian rhythm and intensity of itching in patients. In addition, the patients' disease severity (Eczema Area and Severity Index [EASI]) and quality of life (Dermatology Life Quality Index [DLQI]) were assessed. Itching occurred most frequently (74.69%) and with the greatest severity (62.66%) between 20:00 and 00:00, and the least number of patients (25.31%) experienced itching between 04:00 and 08:00. The DLQI and EASI scores both correlated with the average and maximum itch intensity (r = 0.582, r = 0.533, respectively; r = 0.539, r = 0.517, respectively; p < 0.001). The DLQI and EASI scores were associated with average itch intensity (B = 0.179, B = 0.204, respectively; 95% CI: 0.112 to 0.246, 95% CI: 0.096 to 0.313, respectively; p < 0.001), and the EASI score was associated with males and family history (B = 0.285, B = 0.287, respectively; 95% CI: 0.094 to 0.476, 95% CI: 0.096 to 0.478, respectively; p = 0.003). Adult patients with atopic dermatitis exhibited a circadian rhythm of itching; these study results could positively impact treatment approaches.
特应性皮炎患者的瘙痒模式尚未得到系统研究。因此,本研究旨在评估成人特应性皮炎患者的瘙痒模式,采用问卷调查的方式,对一家机构的参与患者(n = 241)的瘙痒昼夜节律进行评估。该研究采用自我报告问卷来评估患者瘙痒的昼夜节律和强度。此外,还评估了患者的疾病严重程度(湿疹面积和严重程度指数[EASI])和生活质量(皮肤病生活质量指数[DLQI])。瘙痒发生频率最高(74.69%),严重程度最重(62.66%),发生时间为 20:00 至 00:00,而在 04:00 至 08:00 出现瘙痒的患者最少(25.31%)。DLQI 和 EASI 分数均与平均瘙痒强度和最大瘙痒强度相关(分别为 r = 0.582 和 r = 0.533;r = 0.539 和 r = 0.517; p
{"title":"The Circadian Rhythm of Itching among 241 Adults with Atopic Dermatitis: A Cross-sectional Study.","authors":"Xiaoxue Sang, Jianyun Lu, Lina Tan, Jinrong Zeng, Dan Wang, Aiyuan Guo, Siyuan Tang, Qian Zeng, Wei Liu, Lihua Gao","doi":"10.2340/actadv.v104.35427","DOIUrl":"10.2340/actadv.v104.35427","url":null,"abstract":"<p><p>The pattern of itching in patients with atopic dermatitis has not been systematically studied. Therefore, this study aimed to assess the pattern of itching in adults with atopic dermatitis using questionnaires to assess for a circadian rhythm of itching in participating patients at a single institution (n = 241). A self-report questionnaire was used to assess circadian rhythm and intensity of itching in patients. In addition, the patients' disease severity (Eczema Area and Severity Index [EASI]) and quality of life (Dermatology Life Quality Index [DLQI]) were assessed. Itching occurred most frequently (74.69%) and with the greatest severity (62.66%) between 20:00 and 00:00, and the least number of patients (25.31%) experienced itching between 04:00 and 08:00. The DLQI and EASI scores both correlated with the average and maximum itch intensity (r = 0.582, r = 0.533, respectively; r = 0.539, r = 0.517, respectively; p < 0.001). The DLQI and EASI scores were associated with average itch intensity (B = 0.179, B = 0.204, respectively; 95% CI: 0.112 to 0.246, 95% CI: 0.096 to 0.313, respectively; p < 0.001), and the EASI score was associated with males and family history (B = 0.285, B = 0.287, respectively; 95% CI: 0.094 to 0.476, 95% CI: 0.096 to 0.478, respectively; p = 0.003). Adult patients with atopic dermatitis exhibited a circadian rhythm of itching; these study results could positively impact treatment approaches.</p>","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11318504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141888135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-05DOI: 10.2340/actadv.v104.40601
Wolfgang G Philipp-Dormston, Lasse R Braathen, Colin A Morton, Merete Haedersdal, Yolanda Gilaberte, Nicole Basset-Seguin, Elena Sotiriou, Stine Regin Wiegell, Piergiacomo Calzavara-Pinton, Thomas Dirschka, Hans Christian Wulf, Günther Hofbauer, Rolf Markus Szeimies
Keratinocyte-derived skin cancers comprise basal cell carcinoma, squamous cell carcinoma, its precursor actinic keratosis, and Bowen's disease. Historically, this group of neoplasms has been subsumed under the term non-melanoma skin cancer. However, the term non-melanoma skin cancer can be misleading and lacks precision. Therefore, more precise and reasonable terminology, valuing the relevance of keratinocyte-derived cancer, appears pertinent to meet its clinical and scientific significance. A group of experienced dermato-oncologists initiated a consensus approach to promote the use of the term "keratinocyte cancer" instead of "non-melanoma skin cancer" when referring to carcinomas and their precursors that are derived from keratinocytes. The vote among members of the consensus group indicated unanimous agreement on the consistent use of the term "keratinocyte cancer" instead of "non-melanoma skin cancer". International delegates also voted in favour of the revised terminology. The more precise and, by means of etiopathogenesis, correct term "keratinocyte cancer" should be consistently used for malignancies originated from keratinocytes. This is expected to have a positive impact on patient-physician communication and gives better justice to this important group of keratinocyte-derived cancers.
{"title":"A European Consensus on the Consistent Use of the Term \"Keratinocyte Cancer\".","authors":"Wolfgang G Philipp-Dormston, Lasse R Braathen, Colin A Morton, Merete Haedersdal, Yolanda Gilaberte, Nicole Basset-Seguin, Elena Sotiriou, Stine Regin Wiegell, Piergiacomo Calzavara-Pinton, Thomas Dirschka, Hans Christian Wulf, Günther Hofbauer, Rolf Markus Szeimies","doi":"10.2340/actadv.v104.40601","DOIUrl":"10.2340/actadv.v104.40601","url":null,"abstract":"<p><p>Keratinocyte-derived skin cancers comprise basal cell carcinoma, squamous cell carcinoma, its precursor actinic keratosis, and Bowen's disease. Historically, this group of neoplasms has been subsumed under the term non-melanoma skin cancer. However, the term non-melanoma skin cancer can be misleading and lacks precision. Therefore, more precise and reasonable terminology, valuing the relevance of keratinocyte-derived cancer, appears pertinent to meet its clinical and scientific significance. A group of experienced dermato-oncologists initiated a consensus approach to promote the use of the term \"keratinocyte cancer\" instead of \"non-melanoma skin cancer\" when referring to carcinomas and their precursors that are derived from keratinocytes. The vote among members of the consensus group indicated unanimous agreement on the consistent use of the term \"keratinocyte cancer\" instead of \"non-melanoma skin cancer\". International delegates also voted in favour of the revised terminology. The more precise and, by means of etiopathogenesis, correct term \"keratinocyte cancer\" should be consistently used for malignancies originated from keratinocytes. This is expected to have a positive impact on patient-physician communication and gives better justice to this important group of keratinocyte-derived cancers.</p>","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11318500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141888130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-18DOI: 10.2340/actadv.v104.40334
Olivier Maillard, Clotilde Fera, Elisa Joly, Kevin Diallo, Patrick Mavingui, Yves-Marie Diarra, Yatrika Koumar, André Cabié, Antoine Bertolotti
Nearly 4 billion people live in a dengue risk area worldwide. The prevalence of dengue-related mucocutaneous manifestations and their association with severe dengue differ across studies. The aim of the study was to describe the characteristics of patients with dengue-related mucocutaneous manifestations and to investigate those were associated with severe dengue. A retrospective study was conducted in 2019 among patients with a positive RT-PCR for dengue at the University Hospital of Reunion, which has been experiencing a re-emergence of dengue since 2018. Of 847 patients with confirmed dengue, 283 (33.4%) developed mucocutaneous manifestations. Only manifestations of dehydration such as glossitis, dysgeusia, or conjunctivitis were associated with severe dengue, unlike pruritus and rash, in bivariate analysis but not in multivariate analysis. The rash and pruritus of dengue appear to be accompanied by a pronounced flu-like syndrome in younger people without comorbidity or severity, although careful examination of mucous membranes would better identify signs of dehydration and thus cases likely to worsen.
{"title":"Mucocutaneous Manifestations in Patients with Dengue Fever: From the EPIDENGUE Cohort on Reunion Island.","authors":"Olivier Maillard, Clotilde Fera, Elisa Joly, Kevin Diallo, Patrick Mavingui, Yves-Marie Diarra, Yatrika Koumar, André Cabié, Antoine Bertolotti","doi":"10.2340/actadv.v104.40334","DOIUrl":"10.2340/actadv.v104.40334","url":null,"abstract":"<p><p>Nearly 4 billion people live in a dengue risk area worldwide. The prevalence of dengue-related mucocutaneous manifestations and their association with severe dengue differ across studies. The aim of the study was to describe the characteristics of patients with dengue-related mucocutaneous manifestations and to investigate those were associated with severe dengue. A retrospective study was conducted in 2019 among patients with a positive RT-PCR for dengue at the University Hospital of Reunion, which has been experiencing a re-emergence of dengue since 2018. Of 847 patients with confirmed dengue, 283 (33.4%) developed mucocutaneous manifestations. Only manifestations of dehydration such as glossitis, dysgeusia, or conjunctivitis were associated with severe dengue, unlike pruritus and rash, in bivariate analysis but not in multivariate analysis. The rash and pruritus of dengue appear to be accompanied by a pronounced flu-like syndrome in younger people without comorbidity or severity, although careful examination of mucous membranes would better identify signs of dehydration and thus cases likely to worsen.</p>","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262361/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141632309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-18DOI: 10.2340/actadv.v104.40023
Filippos Giannopoulos, Martin Gillstedt, Sofia Lindskogen, John Paoli, Sam Polesie
{"title":"Performance of a Machine Learning Algorithm on Lesions with a High Preoperative Suspicion of Invasive Melanoma.","authors":"Filippos Giannopoulos, Martin Gillstedt, Sofia Lindskogen, John Paoli, Sam Polesie","doi":"10.2340/actadv.v104.40023","DOIUrl":"10.2340/actadv.v104.40023","url":null,"abstract":"","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262359/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141632310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multiple Papules and Nodules Over the Body with Diffuse Thickening of the Facial Skin: A Quiz.","authors":"Aravind Reddy, Yash Buccha, Rohan Manoj, Namratha Puttur, Kshitiz Lakhey","doi":"10.2340/actadv.v104.40206","DOIUrl":"10.2340/actadv.v104.40206","url":null,"abstract":"","PeriodicalId":6944,"journal":{"name":"Acta dermato-venereologica","volume":null,"pages":null},"PeriodicalIF":3.5,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262363/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141615629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}