Pub Date : 2022-05-15DOI: 10.30565/medalanya.1066381
Ahmet Özşi̇mşek, Ertan Karaçay
Amaç: Kliniğimize baş dönmesi şikâyeti ile başvurup idiopathic benign paroksismal pozisyonel vertigo (BPPV) tanısı alan hastalar ile baş dönmesi olmayan sağlıklı kontrol grubunun 25-hidroksi vitamin D (25-OH vitamin D) ve Ca2+ düzeylerinin karşılaştırılması Ca2+ ve 25-OH vitamin D’nin BPPV gelişimindeki rolünün araştırılmasıdır. Gereç ve Yöntem: Çalışmamız geriye dönük vaka kontrol çalışması olup, 01.01.2018-01.08.2021 arası Alanya Egitim ve Araştırma Hastanesi Nöroloji polikliniğine başvuran İdiopatik BPPV tanısı alan 409 hasta ile kontrol grubu olarak kliniğimize başvuru öncesi son 1 yıl içerisinde vertigo, dizziness ya da dengesizlik nedeniyle hekim başvurusu olmayan serum D vitamini düzeyi ölçümü yapılmış 338 hasta seçilerek oluşturuldu. İstatiksel değerlendirmeler için ki-kare ve T testi testi kullanıldı. Bulgular: Ortalama serum 25-OH vitamin D düzeyleri BPPV ve kontrol grubunda sırasıyla 15,74 ng/mL ve 17,91 ng/mL idi. Serum 25-OH vitamin D düzeyleri BPPV grubunda kontrol grubuna göre anlamlı derecede düşük bulundu ((p=0,01, p
{"title":"Serum 25-Hidroksi D Vitamini ve Kalsiyum Seviyeleri ile İdiyopatik Benign Paroksismal Pozisyonel Vertigo Arasındaki İlişki","authors":"Ahmet Özşi̇mşek, Ertan Karaçay","doi":"10.30565/medalanya.1066381","DOIUrl":"https://doi.org/10.30565/medalanya.1066381","url":null,"abstract":"Amaç: Kliniğimize baş dönmesi şikâyeti ile başvurup idiopathic benign paroksismal pozisyonel vertigo (BPPV) tanısı alan hastalar ile baş dönmesi olmayan sağlıklı kontrol grubunun 25-hidroksi vitamin D (25-OH vitamin D) ve Ca2+ düzeylerinin karşılaştırılması Ca2+ ve 25-OH vitamin D’nin BPPV gelişimindeki rolünün araştırılmasıdır. \u0000Gereç ve Yöntem: Çalışmamız geriye dönük vaka kontrol çalışması olup, 01.01.2018-01.08.2021 arası Alanya Egitim ve Araştırma Hastanesi Nöroloji polikliniğine başvuran İdiopatik BPPV tanısı alan 409 hasta ile kontrol grubu olarak kliniğimize başvuru öncesi son 1 yıl içerisinde vertigo, dizziness ya da dengesizlik nedeniyle hekim başvurusu olmayan serum D vitamini düzeyi ölçümü yapılmış 338 hasta seçilerek oluşturuldu. İstatiksel değerlendirmeler için ki-kare ve T testi testi kullanıldı. \u0000 Bulgular: Ortalama serum 25-OH vitamin D düzeyleri BPPV ve kontrol grubunda sırasıyla 15,74 ng/mL ve 17,91 ng/mL idi. Serum 25-OH vitamin D düzeyleri BPPV grubunda kontrol grubuna göre anlamlı derecede düşük bulundu ((p=0,01, p","PeriodicalId":7003,"journal":{"name":"Acta Medica Alanya","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89375465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-08DOI: 10.30565/medalanya.1055424
Mukaddes Pala, M. Altan, Ferahat Hani̇koglu, Salim Neşelioğlu, Özcan Erel, Gökhan Metin
Amaç: Tiyol/disülfid homeostazı, oksidatif stresin ve antioksidan kapasitenin bir göstergesidir. İskemi-modifiye albümin (İMA), hem oksidatif stres hem de iskemi için önemli bir belirteçtir. Düzenli olarak uygulanan orta şiddetteki egzersizin tiyol/disülfid homeostazı ve IMA seviyeleri üzerine olası etkilerini değerlendirmeyi amaçladık. Metot: Sprague-Dawley sıçanlar kullanıldı. Çalışma, Egzersiz grubu (EG, n=9) ve Kontrol grubundan (KG, n=6) oluşturuldu. 10 haftalık bir yüzme egzersizi yaptırıldı. Bu çalışmada tiyol/disülfid homeostazı ölçüm yöntemi kullanıldı. IMA seviyeleri, bir kobalt-albümin bağlama yöntemiyle ölçüldü. Bulgular: EG'de, total tiyol seviyeleri KG ile karşılaştırıldığında anlamlı derecede daha yüksekti (p
{"title":"Düzenli olarak uygulanan orta şiddetteki egzersiz programının tiyol/disülfid homeostazı ve iskemi modifiye albümin üzerine etkisi","authors":"Mukaddes Pala, M. Altan, Ferahat Hani̇koglu, Salim Neşelioğlu, Özcan Erel, Gökhan Metin","doi":"10.30565/medalanya.1055424","DOIUrl":"https://doi.org/10.30565/medalanya.1055424","url":null,"abstract":"Amaç: Tiyol/disülfid homeostazı, oksidatif stresin ve antioksidan kapasitenin bir göstergesidir. İskemi-modifiye albümin (İMA), hem oksidatif stres hem de iskemi için önemli bir belirteçtir. Düzenli olarak uygulanan orta şiddetteki egzersizin tiyol/disülfid homeostazı ve IMA seviyeleri üzerine olası etkilerini değerlendirmeyi amaçladık. \u2028Metot: Sprague-Dawley sıçanlar kullanıldı. Çalışma, Egzersiz grubu (EG, n=9) ve Kontrol grubundan (KG, n=6) oluşturuldu. 10 haftalık bir yüzme egzersizi yaptırıldı. Bu çalışmada tiyol/disülfid homeostazı ölçüm yöntemi kullanıldı. IMA seviyeleri, bir kobalt-albümin bağlama yöntemiyle ölçüldü. \u2028Bulgular: EG'de, total tiyol seviyeleri KG ile karşılaştırıldığında anlamlı derecede daha yüksekti (p","PeriodicalId":7003,"journal":{"name":"Acta Medica Alanya","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74529803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-27DOI: 10.30565/medalanya.1070971
Duygu Çalişkan, A. Kuybulu
Aim: The aim of this study is to evaluate the clinical and laboratory features and prognosis of scorpion stings in children. Methods: This retrospective study was in children with scorpion stings who were admitted to the pediatric emergency department in Alanya Alaaddin Keykubat University (ALKU) Training and Research Hospital between 1st of January 2019-31 st of December 2020. Demographic data, admission date, time intervals from sting to admission to hospital, geographical location in which the sting occurred, affected body sites, local and systemic signs and symptoms of envenomation, results of hematological and biochemical laboratory tests, management, length of hospital stay, and outcome were recorded. Results: Totally, medical records of 111 children were reviewed. Patients were divided according to the clinical findings into 3 groups, 70 patients (63.1%) with mild symptoms, 34 patients (30.6%) with moderate symptoms, 7 patients (29%) with severe symptoms. There was one exitus due to scorpion stings in the study period. Fortyone (37%) patients were hospitalised and 7 patients (%63) had hospitalisation in the pediatric intensive care unit. Five patients (4%) received doxasozin and 19 (17%) patients had antivenom therapy. Hospitalization in the intensive care unit was required for seven cases. No patient presented sequelae at the hospital discharge. Conclusions: Scorpion stings in our region mostly end up with mild envenomation. Doxazosin also a prazosin analog, which is more easily available in our country can be considered as a treatment option in serious scorpion envenomations with significant sympathetic symptoms.
{"title":"Güneybatı Türkiye'de Çocuklarda Akrep Sokması: Bir Eğitim ve Araştırma Hastanesi Deneyimi","authors":"Duygu Çalişkan, A. Kuybulu","doi":"10.30565/medalanya.1070971","DOIUrl":"https://doi.org/10.30565/medalanya.1070971","url":null,"abstract":"Aim: The aim of this study is to evaluate the clinical and laboratory features and prognosis of scorpion stings in children. \u0000Methods: This retrospective study was in children with scorpion stings who were admitted to the pediatric emergency department in Alanya Alaaddin Keykubat University (ALKU) Training and Research Hospital between 1st of January 2019-31 st of December 2020. Demographic data, admission date, time intervals from sting to admission to hospital, geographical location in which the sting occurred, affected body sites, local and systemic signs and symptoms of envenomation, results of hematological and biochemical laboratory tests, management, length of hospital stay, and outcome were recorded. \u0000Results: Totally, medical records of 111 children were reviewed. Patients were divided according to the clinical findings into 3 groups, 70 patients (63.1%) with mild symptoms, 34 patients (30.6%) with moderate symptoms, 7 patients (29%) with severe symptoms. There was one exitus due to scorpion stings in the study period. Fortyone (37%) patients were hospitalised and 7 patients (%63) had hospitalisation in the pediatric intensive care unit. Five patients (4%) received doxasozin and 19 (17%) patients had antivenom therapy. Hospitalization in the intensive care unit was required for seven cases. No patient presented sequelae at the hospital discharge. \u0000Conclusions: Scorpion stings in our region mostly end up with mild envenomation. Doxazosin also a prazosin analog, which is more easily available in our country can be considered as a treatment option in serious scorpion envenomations with significant sympathetic symptoms.","PeriodicalId":7003,"journal":{"name":"Acta Medica Alanya","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74232472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-19DOI: 10.30565/medalanya.1084062
A. Aksoy, S. Sargin, A. Atik, Anıl Gülcü
{"title":"Has the Covid-19 pandemic affected the practice of Orthopedics and Traumatology?","authors":"A. Aksoy, S. Sargin, A. Atik, Anıl Gülcü","doi":"10.30565/medalanya.1084062","DOIUrl":"https://doi.org/10.30565/medalanya.1084062","url":null,"abstract":"","PeriodicalId":7003,"journal":{"name":"Acta Medica Alanya","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74694515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-14DOI: 10.30565/medalanya.1086508
Akif Ayaz, B. Yulug
Aim: In this study, the relationship between genetic analysis and exome sequencing and clinical and neuroimaging findings of four patients from the same family was investigated by analyzing a clinical and genetic (WES) database containing more than 3000 patients. Methods: We analyzed the WES data of approximately 3000 patients performed in our center in terms of NTNG2 biallelic mutations. In addition, MR imaging findings were investigated. Results: We found four patients with the same mutation in the NTNG2 gene, presenting with similar clinical and neuroimaging findings. As a result of filtering, the c242G>A variant was determined in the NTNG2 gene. In addition, mild to severe brain parenchymal volume loss and frontal and temporal lobe atrophy were seen in cases 1, 2, and 4 on axial T2-weighted MRI. c. Conclusion: The current study has similar phenotypic and genotypic features and is a very rare report showing NTNG2 mutation in this context. Existing clinical data are important in choosing NTNG2 gene-related neuropsychiatric disorders as a future treatment target.
{"title":"NTNG2 Mutation: A candidate gene for a new brain-skin disorder with early neuropsychiatric manifestation? An analysis based on 3000 patients","authors":"Akif Ayaz, B. Yulug","doi":"10.30565/medalanya.1086508","DOIUrl":"https://doi.org/10.30565/medalanya.1086508","url":null,"abstract":"Aim: In this study, the relationship between genetic analysis and exome sequencing and clinical and neuroimaging findings of four patients from the same family was investigated by analyzing a clinical and genetic (WES) database containing more than 3000 patients. Methods: We analyzed the WES data of approximately 3000 patients performed in our center in terms of NTNG2 biallelic mutations. In addition, MR imaging findings were investigated. Results: We found four patients with the same mutation in the NTNG2 gene, presenting with similar clinical and neuroimaging findings. As a result of filtering, the c242G>A variant was determined in the NTNG2 gene. In addition, mild to severe brain parenchymal volume loss and frontal and temporal lobe atrophy were seen in cases 1, 2, and 4 on axial T2-weighted MRI. c. Conclusion: The current study has similar phenotypic and genotypic features and is a very rare report showing NTNG2 mutation in this context. Existing clinical data are important in choosing NTNG2 gene-related neuropsychiatric disorders as a future treatment target.","PeriodicalId":7003,"journal":{"name":"Acta Medica Alanya","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82494236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-18DOI: 10.30565/medalanya.1052586
U. Yiğit, F. Kırzıoğlu, Ö. Özmen, Yrd.doç.dr. Abdülhadi Uğuz
{"title":"Effects of LDD and CAPE administration on total antioxidant and total oxidant levels in experimental periodontitis model of rat brain","authors":"U. Yiğit, F. Kırzıoğlu, Ö. Özmen, Yrd.doç.dr. Abdülhadi Uğuz","doi":"10.30565/medalanya.1052586","DOIUrl":"https://doi.org/10.30565/medalanya.1052586","url":null,"abstract":"","PeriodicalId":7003,"journal":{"name":"Acta Medica Alanya","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88368248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-08DOI: 10.30565/medalanya.995148
Mehmet Kubat, S. Şahin
{"title":"Validation and Efficiency of a Scoring System Used in the Differentiation of Uncomplicated Appendicitis","authors":"Mehmet Kubat, S. Şahin","doi":"10.30565/medalanya.995148","DOIUrl":"https://doi.org/10.30565/medalanya.995148","url":null,"abstract":"","PeriodicalId":7003,"journal":{"name":"Acta Medica Alanya","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90346968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-22DOI: 10.30565/medalanya.1025510
Duran Topak, Mustafa Abdullah Özdemi̇r, Fatih Doğar, Ökkeş Bilal
{"title":"Pediatrik femur boyun kırıklarının cerrahi tedavisinin fonksiyonel ve radyolojik sonuçları","authors":"Duran Topak, Mustafa Abdullah Özdemi̇r, Fatih Doğar, Ökkeş Bilal","doi":"10.30565/medalanya.1025510","DOIUrl":"https://doi.org/10.30565/medalanya.1025510","url":null,"abstract":"","PeriodicalId":7003,"journal":{"name":"Acta Medica Alanya","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89948762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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