R. Vogelaerts, L. Van Pachtenbeke, M. Raudsepp, B. Morlion
Objective: This paper reviews the prevalence, etiology, risk factors, diagnosis and prevention of chronic abdominal pain after bariatric surgery. Introduction: Chronic pain is a very common and complex problem that has serious consequences on individuals and society. It frequently presents as a result of a disease or an injury. Obesity and obesity-related comorbidities are a major health problem and are dramatically increasing year after year. Dieting and physical exercise show disappointing results in the treatment of obesity. Therefore, bariatric surgery is increasingly widely offered as a weight reducing strategy. In our pain clinic we see a lot of patients who suffer from chronic abdominal pain after bariatric surgery. This review aims to explore the link between chronic abdominal pain and bariatric surgery in this specific type of patients. Method: The review is based on searches in PubMed, Embase and Cochrane databases. Keywords are used in different combinations. We did a cross-reference of the articles included. Results: Chronic abdominal pain after bariatric surgery is very common. Around 30% of the bariatric patients experience persistent abdominal pain. An explanation for the abdominal pain is found in 2/3 of these patients. There is a wide variety of causes including behavioral and nutritional disorders, functional motility disorders, biliary disorders, marginal ulceration and internal hernia. Another, frequently overlooked, cause is abdominal wall pain. Unexplained abdominal pain after bariatric surgery is present in 1/3 of the patients with persistent abdominal pain. More studies are needed on the risk factors and prevention of unexplained abdominal pain in bariatric patients.
{"title":"Chronic abdominal pain after bariatric surgery: a narrative review","authors":"R. Vogelaerts, L. Van Pachtenbeke, M. Raudsepp, B. Morlion","doi":"10.56126/73.4.26","DOIUrl":"https://doi.org/10.56126/73.4.26","url":null,"abstract":"Objective: This paper reviews the prevalence, etiology, risk factors, diagnosis and prevention of chronic abdominal pain after bariatric surgery.\u0000\u0000Introduction: Chronic pain is a very common and complex problem that has serious consequences on individuals and society. It frequently presents as a result of a disease or an injury. Obesity and obesity-related comorbidities are a major health problem and are dramatically increasing year after year. Dieting and physical exercise show disappointing results in the treatment of obesity. Therefore, bariatric surgery is increasingly widely offered as a weight reducing strategy. In our pain clinic we see a lot of patients who suffer from chronic abdominal pain after bariatric surgery. This review aims to explore the link between chronic abdominal pain and bariatric surgery in this specific type of patients.\u0000\u0000Method: The review is based on searches in PubMed, Embase and Cochrane databases. Keywords are used in different combinations. We did a cross-reference of the articles included.\u0000\u0000Results: Chronic abdominal pain after bariatric surgery is very common. Around 30% of the bariatric patients experience persistent abdominal pain. An explanation for the abdominal pain is found in 2/3 of these patients.\u0000There is a wide variety of causes including behavioral and nutritional disorders, functional motility disorders, biliary disorders, marginal ulceration and internal hernia. Another, frequently overlooked, cause is abdominal wall pain. Unexplained abdominal pain after bariatric surgery is present in 1/3 of the patients with persistent abdominal pain. More studies are needed on the risk factors and prevention of unexplained abdominal pain in bariatric patients.","PeriodicalId":7024,"journal":{"name":"Acta anaesthesiologica Belgica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43754341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Dincq, L. Thiltges, I. Michaux, M. Gourdin, G. Kalscheuer, L. Melly, M. Gillet, M. Bareille, S. Lessire, M. Hardy
Background: Cardiac surgery is associated with a high rate of intraoperative transfusion, requiring pre- ordering or ordering of packed red blood cell (PRBC) before surgery. Our institutional strategy is based on a systematic type and screen (T/S) ordering of 3 PRBCs at the blood bank then stored in a dedicated refrigerator in the operating room for each patient scheduled for cardiac surgery. However, these PRBC units are not always transfused and are therefore at risk of destruction if temperature fluctuations are detected during transport and storage processes. In addition, these orders represent a burden for the blood bank. Therefore, it is relevant to move towards a more tailored PRBC order before cardiac surgery and challenge the systematic ordering protocol. Methods: The Transfusion Understanding Scoring Tool (TRUST) and the Transfusion Risk and Clinical Knowledge (TRACK) Score are designed to stratify blood transfusion needs in cardiac surgery. We retrospectively performed both scores for each patient scheduled for cardiac surgery. Then, we compared their performance to predict PRBC transfusion and determined the optimal threshold to optimize the preoperative PRBC order reflecting the needs of our population managed with our local standards. Results: Receiver operating characteristic (ROC) curves for prediction of PRBC transfusion using the two scores were computed for the whole cohort (n=1249). Both scores performed well (areas under ROC curves: 0.81 and 0.82 (95% CI) using the TRACK Score and the TRUST, respectively). A TRUST < 3 identified a subgroup of patients (53.6%) at low risk of transfusion. The availability of 1 T/S PRBC in the OR would cover the needs of the majority (92.5%) of this group. Conclusions: In our institution, the use of the TRUST preoperatively could offer a more tailored T/S PRBC order for the intraoperative period, especially in the low-risk transfusion group.
{"title":"Towards optimized red blood cells ordering prior to cardiac surgery: a single center retrospective study","authors":"A. Dincq, L. Thiltges, I. Michaux, M. Gourdin, G. Kalscheuer, L. Melly, M. Gillet, M. Bareille, S. Lessire, M. Hardy","doi":"10.56126/73.4.24","DOIUrl":"https://doi.org/10.56126/73.4.24","url":null,"abstract":"Background: Cardiac surgery is associated with a high rate of intraoperative transfusion, requiring pre- ordering or ordering of packed red blood cell (PRBC) before surgery. Our institutional strategy is based on a systematic type and screen (T/S) ordering of 3 PRBCs at the blood bank then stored in a dedicated refrigerator in the operating room for each patient scheduled for cardiac surgery. However, these PRBC units are not always transfused and are therefore at risk of destruction if temperature fluctuations are detected during transport and storage processes. In addition, these orders represent a burden for the blood bank. Therefore, it is relevant to move towards a more tailored PRBC order before cardiac surgery and challenge the systematic ordering protocol.\u0000\u0000Methods: The Transfusion Understanding Scoring Tool (TRUST) and the Transfusion Risk and Clinical Knowledge (TRACK) Score are designed to stratify blood transfusion needs in cardiac surgery. We retrospectively performed both scores for each patient scheduled for cardiac surgery. Then, we compared their performance to predict PRBC transfusion and determined the optimal threshold to optimize the preoperative PRBC order reflecting the needs of our population managed with our local standards.\u0000\u0000Results: Receiver operating characteristic (ROC) curves for prediction of PRBC transfusion using the two scores were computed for the whole cohort (n=1249). Both scores performed well (areas under ROC curves: 0.81 and 0.82 (95% CI) using the TRACK Score and the TRUST, respectively). A TRUST < 3 identified a subgroup of patients (53.6%) at low risk of transfusion. The availability of 1 T/S PRBC in the OR would cover the needs of the majority (92.5%) of this group.\u0000\u0000Conclusions: In our institution, the use of the TRUST preoperatively could offer a more tailored T/S PRBC order for the intraoperative period, especially in the low-risk transfusion group.","PeriodicalId":7024,"journal":{"name":"Acta anaesthesiologica Belgica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70729994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: There is insufficient evidence to recommend using either intraoperative cerebral oximetry or (processed) electroencephalogram (EEG) alone for preventing perioperative neurocognitive disorders (PNDs). Objective: To evaluate the effectiveness of combined use of cerebral oximetry and electroencephalogram-guided anesthesia on the incidence of PNDs in adult patients undergoing cardiac and non-cardiac interventions. Methods: A PICOS - based systematic review of English articles using Pubmed and Embase (from inception to August 2022) was performed. There were no exclusion criteria regarding the type of the study. Abstract proceedings and new study protocols or ongoing studies were not included. Review articles were analyzed in search of eligible references. All possible terms that were illustrative of PNDs were used. Results: Among the 63 full manuscripts that were analyzed in detail, 15 met the inclusion criteria. We found 2 retrospective, 8 prospective observational and 5 randomized controlled trials of which 1 did not evaluate the use of neuromonitoring in the randomization process. The definition and the methods used to diagnose PNDs were very heterogeneous. Only 8 studies used an algorithm to avoid/treat cerebral oxygen desaturation and/or to treat EEG abnormalities. Overall, there was a tendency towards less PNDs in studies where such an algorithm was used. Conclusions: Our results suggest that integrating information obtained from cerebral oximetry and an EEG monitor may reduce the incidence of PNDs whenever an adapted algorithm is used to improve brain function.
{"title":"Effect of combined use of cerebral oximetry and electroencephalogram monitoring on the incidence of perioperative neurocognitive disorders in adult cardiac and non-cardiac surgery: A systematic review of randomized and non-randomized trials","authors":"Q. Souberbielle, A. Jacobs Sariyar, M. Momeni","doi":"10.56126/73.4.30","DOIUrl":"https://doi.org/10.56126/73.4.30","url":null,"abstract":"Background: There is insufficient evidence to recommend using either intraoperative cerebral oximetry or (processed) electroencephalogram (EEG) alone for preventing perioperative neurocognitive disorders (PNDs).\u0000\u0000Objective: To evaluate the effectiveness of combined use of cerebral oximetry and electroencephalogram-guided anesthesia on the incidence of PNDs in adult patients undergoing cardiac and non-cardiac interventions.\u0000\u0000Methods: A PICOS - based systematic review of English articles using Pubmed and Embase (from inception to August 2022) was performed. There were no exclusion criteria regarding the type of the study. Abstract proceedings and new study protocols or ongoing studies were not included. Review articles were analyzed in search of eligible references. All possible terms that were illustrative of PNDs were used.\u0000\u0000Results: Among the 63 full manuscripts that were analyzed in detail, 15 met the inclusion criteria. We found 2 retrospective, 8 prospective observational and 5 randomized controlled trials of which 1 did not evaluate the use of neuromonitoring in the randomization process. The definition and the methods used to diagnose PNDs were very heterogeneous. Only 8 studies used an algorithm to avoid/treat cerebral oxygen desaturation and/or to treat EEG abnormalities. Overall, there was a tendency towards less PNDs in studies where such an algorithm was used.\u0000\u0000Conclusions: Our results suggest that integrating information obtained from cerebral oximetry and an EEG monitor may reduce the incidence of PNDs whenever an adapted algorithm is used to improve brain function.","PeriodicalId":7024,"journal":{"name":"Acta anaesthesiologica Belgica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46702893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Ki, E. Zoumènou, M. Chobli, B. le Polain de Waroux, A. Robert, P. Baele
Background: For unknown reasons female participation in anesthesiology is very low in Sub-Saharan Africa (SSA), especially in West Africa, and few women reach top academic or clinical positions. Objective: Women reduced professional perspectives. Design: Male and female residents’ performances were compared when they presented for their first try the graduating exams of the specialty. Settings: The Cotonou anesthesiology and intensive care training center, the second largest in French-speaking SSA, where 146 anesthesiologists from 14 African countries graduated since its creation in 1996. Method: All results at their final exams (consisting in 3 written questions and 2 clinical evaluations) were retrieved for the 125 men and 21 women who graduated. Scores obtained by women and males were compared using Student’s t tests. Their total of points was used to divide graduates into deciles. The proportion of women was counted in each decile. Results: Women performed better at both anesthesia and intensive care clinical evaluations taken separately and together (total 68.2% vs. 64.2% p=0.004) and were even with men for the three written exams (anesthesia, intensive care and basic sciences - total 66.2 % vs. 66.1% p=0.99). When clinical and written scores are added in each sector, women scored better than males for anesthesiology (69.2% vs. 65.2% p=0.01) and were even for intensive care (65.0% vs. 64.1% p=0.51). Globally women and men results were similar (67% vs. 65%, p=0.1) The proportion of women in each decile increased from the lowest to the best deciles, but the absolute low number of women gives this trend borderline significance (slope +1,56 % women per decile, p=0.046)**. Conclusion: Women performance at end-specialty exams is unlikely to explain their subsequent underrepresentation at the academic level in anesthesia and intensive care in SSA**.
背景:由于未知的原因，在撒哈拉以南非洲(SSA)，特别是西非，女性参与麻醉学的比例非常低，很少有女性达到顶级学术或临床职位。目的:女性减少职业视角。设计:比较男性和女性住院医师首次参加专业毕业考试时的表现。环境:科托努麻醉学和重症监护培训中心，法语SSA第二大培训中心，自1996年成立以来，已有来自14个非洲国家的146名麻醉师毕业。方法:检索125名男性和21名女性毕业生的所有期末考试成绩(包括3个书面问题和2个临床评估)。女性和男性获得的分数使用学生t检验进行比较。他们的总分被用来把毕业生分成十分位数。妇女的比例按十分位数计算。结果:女性在麻醉和重症监护临床评估中分别表现更好(68.2% vs. 64.2% p=0.004)，并且在三个笔试(麻醉、重症监护和基础科学- 66.2% vs. 66.1% p=0.99)中与男性表现相同。将各科室的临床和书面评分相加，女性在麻醉科的得分高于男性(69.2%比65.2% p=0.01)，甚至在重症监护科的得分也高于男性(65.0%比64.1% p=0.51)。在全球范围内，女性和男性的结果是相似的(67%对65%，p=0.1)，女性在每个十分位数中的比例从最低的十分位数增加到最好的十分位数，但女性的绝对低数量使这一趋势具有临界意义(斜率+1，每十分位数56%的女性，p=0.046)**。结论:女性在终末专科考试中的表现不太可能解释她们随后在SSA麻醉和重症监护学术水平上的代表性不足。
{"title":"Gender and graduating results in the Anesthesiology and Intensive Care Abomey-Calavi (Cotonou, Benin) program","authors":"B. Ki, E. Zoumènou, M. Chobli, B. le Polain de Waroux, A. Robert, P. Baele","doi":"10.56126/73.4.25","DOIUrl":"https://doi.org/10.56126/73.4.25","url":null,"abstract":"Background: For unknown reasons female participation in anesthesiology is very low in Sub-Saharan Africa (SSA), especially in West Africa, and few women reach top academic or clinical positions.\u0000\u0000Objective: Women reduced professional perspectives.\u0000\u0000Design: Male and female residents’ performances were compared when they presented for their first try the graduating exams of the specialty.\u0000\u0000Settings: The Cotonou anesthesiology and intensive care training center, the second largest in French-speaking SSA, where 146 anesthesiologists from 14 African countries graduated since its creation in 1996.\u0000\u0000Method: All results at their final exams (consisting in 3 written questions and 2 clinical evaluations) were retrieved for the 125 men and 21 women who graduated. Scores obtained by women and males were compared using Student’s t tests. Their total of points was used to divide graduates into deciles. The proportion of women was counted in each decile.\u0000\u0000Results: Women performed better at both anesthesia and intensive care clinical evaluations taken separately and together (total 68.2% vs. 64.2% p=0.004) and were even with men for the three written exams (anesthesia, intensive care and basic sciences - total 66.2 % vs. 66.1% p=0.99). When clinical and written scores are added in each sector, women scored better than males for anesthesiology (69.2% vs. 65.2% p=0.01) and were even for intensive care (65.0% vs. 64.1% p=0.51). Globally women and men results were similar (67% vs. 65%, p=0.1) The proportion of women in each decile increased from the lowest to the best deciles, but the absolute low number of women gives this trend borderline significance (slope +1,56 % women per decile, p=0.046)**.\u0000\u0000Conclusion: Women performance at end-specialty exams is unlikely to explain their subsequent underrepresentation at the academic level in anesthesia and intensive care in SSA**.","PeriodicalId":7024,"journal":{"name":"Acta anaesthesiologica Belgica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48209794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chronic post-surgical pain (CPSP) stands as a major health issue. The unchanged incidence over the last two decades underlines both the failure of predictive models developed until now and the lack of efficacy of common “preventive” strategies (pharmacotherapy and regional analgesic techniques) applied in current clinical practice. The recognition of CPSP as a disease and the release of a common definition of the condition is an important progress in the field. CPSP predictive scores exist but none has presently demonstrated an impact on patient care. New clinical directions based on the resolution of postoperative pain, a complex and highly dynamic process supported by individual pain trajectories, argue for predictive models and preventive strategies extended to the subacute pain period i.e. after hospital discharge.
{"title":"Chronic pain after surgery and trauma: current situation and future directions","authors":"P. Lavand'homme","doi":"10.56126/73.4.27","DOIUrl":"https://doi.org/10.56126/73.4.27","url":null,"abstract":"Chronic post-surgical pain (CPSP) stands as a major health issue. The unchanged incidence over the last two decades underlines both the failure of predictive models developed until now and the lack of efficacy of common “preventive” strategies (pharmacotherapy and regional analgesic techniques) applied in current clinical practice. The recognition of CPSP as a disease and the release of a common definition of the condition is an important progress in the field. CPSP predictive scores exist but none has presently demonstrated an impact on patient care. New clinical directions based on the resolution of postoperative pain, a complex and highly dynamic process supported by individual pain trajectories, argue for predictive models and preventive strategies extended to the subacute pain period i.e. after hospital discharge.","PeriodicalId":7024,"journal":{"name":"Acta anaesthesiologica Belgica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41656585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Hof, O. Old, A. Steinbicker, P. Meybohm, S. Choorapoikayil, K. Zacharowski
Iron is an essential element and involved in a variety of metabolic processes including oxygen transport, cellular energy production, energy metabolism of heart muscles, brain function, cell growth and cell differentiation. Preoperative anaemia is an independent risk factor for poor outcome. Recently, iron deficiency was considered only in the context of anaemia. However, negative consequences of iron deficiency in the absence of anaemia have been described for patients undergoing cardiac surgery. To date, the benefit of intravenous iron supplementation in these patients has been controversially debated. In this review, we discuss the latest progress in studies of intravenous iron supplementation in iron deficient cardiac surgical patients.
{"title":"Iron deficiency in cardiac surgical patients","authors":"L. Hof, O. Old, A. Steinbicker, P. Meybohm, S. Choorapoikayil, K. Zacharowski","doi":"10.56126/73.4.28","DOIUrl":"https://doi.org/10.56126/73.4.28","url":null,"abstract":"Iron is an essential element and involved in a variety of metabolic processes including oxygen transport, cellular energy production, energy metabolism of heart muscles, brain function, cell growth and cell differentiation. Preoperative anaemia is an independent risk factor for poor outcome. Recently, iron deficiency was considered only in the context of anaemia. However, negative consequences of iron deficiency in the absence of anaemia have been described for patients undergoing cardiac surgery. To date, the benefit of intravenous iron supplementation in these patients has been controversially debated. In this review, we discuss the latest progress in studies of intravenous iron supplementation in iron deficient cardiac surgical patients.","PeriodicalId":7024,"journal":{"name":"Acta anaesthesiologica Belgica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44604010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Intraoperative sympathetic stimulation induces a cascade of metabolic and hormonal changes. It increases perfusion of vital organs, but also causes vasoconstriction of blood vessels supplying less vital organs, potentially leading to organ injury. To date, it is unknown how an endogenous stress reaction affects the spinal cord blood supply. Near-infrared spectroscopy (NIRS) can be applied paravertebrally to monitor the oxygenation of the collateral network, which contributes to the spinal cord blood supply. It has already been demonstrated that regional cerebral oxygen saturation (rScO2) increases following sympathetic stimulation. Objectives: We hypothesized that laryngoscopy would cause an increase in cerebral and paraspinal regional tissue saturations (rScO2 and rSpsO2, respectively). Design: Retrospective analysis of a previous conducted randomized trial. Setting: Laryngoscopy in the operating room. Methods: Data of 28 patients, scheduled for arterial dilation of the lower limb, were retrospectively analyzed. Before induction of anesthesia, standard monitoring, BIS and 8 NIRS sensors were applied (two on the forehead, six bilaterally on the back at T3-T4, T9-T10 and L1-L2). Sympathetic stimulation was induced by laryngoscopy. Main outcome measures: Changes in rStO2 following sympathetic stimulation induced by laryngoscopy. Results: Following laryngoscopy, rScO2 significantly increased and rSpsO2 significantly decreased at T9-T10 and L1-L2. The relative changes (regional tissue oxygen saturation (rStO2) after intubation-rStO2 before intubation)/ rStO2 before intubation), at cerebral level, T9-T10 and L1-L2 were 9%, -5% and -3%, respectively (p < 0.01). rSpsO2 at T3-T4 did not change significantly. Changes (Δ) in mean arterial pressure following laryngoscopy were weakly correlated with ΔrScO2 and moderately correlated with ΔrSpsO2 at T9-T10 and L1-L2. Conclusions: Intraoperative sympathetic stimulation may decrease the oxygen supply to the spinal cord. Trial registration: The trial was registered at ClinicalTrials.gov (NCT 03767296).
{"title":"Laryngoscopy mediated stress response induces opposite effects on cerebral and paraspinal oxygen saturation","authors":"C. Vanpeteghem, S. D. De Hert, A. Moerman","doi":"10.56126/73.4.29","DOIUrl":"https://doi.org/10.56126/73.4.29","url":null,"abstract":"Background: Intraoperative sympathetic stimulation induces a cascade of metabolic and hormonal changes. It increases perfusion of vital organs, but also causes vasoconstriction of blood vessels supplying less vital organs, potentially leading to organ injury. To date, it is unknown how an endogenous stress reaction affects the spinal cord blood supply. Near-infrared spectroscopy (NIRS) can be applied paravertebrally to monitor the oxygenation of the collateral network, which contributes to the spinal cord blood supply. It has already been demonstrated that regional cerebral oxygen saturation (rScO2) increases following sympathetic stimulation.\u0000\u0000Objectives: We hypothesized that laryngoscopy would cause an increase in cerebral and paraspinal regional tissue saturations (rScO2 and rSpsO2, respectively).\u0000\u0000Design: Retrospective analysis of a previous conducted randomized trial.\u0000\u0000Setting: Laryngoscopy in the operating room.\u0000\u0000Methods: Data of 28 patients, scheduled for arterial dilation of the lower limb, were retrospectively analyzed. Before induction of anesthesia, standard monitoring, BIS and 8 NIRS sensors were applied (two on the forehead, six bilaterally on the back at T3-T4, T9-T10 and L1-L2). Sympathetic stimulation was induced by laryngoscopy.\u0000\u0000Main outcome measures: Changes in rStO2 following sympathetic stimulation induced by laryngoscopy.\u0000\u0000Results: Following laryngoscopy, rScO2 significantly increased and rSpsO2 significantly decreased at T9-T10 and L1-L2. The relative changes (regional tissue oxygen saturation (rStO2) after intubation-rStO2 before intubation)/ rStO2 before intubation), at cerebral level, T9-T10 and L1-L2 were 9%, -5% and -3%, respectively (p < 0.01). rSpsO2 at T3-T4 did not change significantly. Changes (Δ) in mean arterial pressure following laryngoscopy were weakly correlated with ΔrScO2 and moderately correlated with ΔrSpsO2 at T9-T10 and L1-L2.\u0000\u0000Conclusions: Intraoperative sympathetic stimulation may decrease the oxygen supply to the spinal cord.\u0000\u0000Trial registration: The trial was registered at ClinicalTrials.gov (NCT 03767296).","PeriodicalId":7024,"journal":{"name":"Acta anaesthesiologica Belgica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46763167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Perioperative fluid management in children has been a major topic for debate. Objectives: Our aim is to review the current evidence on perioperative fluid management in children including: type of fluid, administration rates, preoperative fluid intake and monitoring techniques. Design: Narrative review. Method: Following the PRISMA-S guidelines we performed a search (2010-March 2022) in databases Medline (through PubMed) and Cochrane Library. 4297 citations were found and screened by two independent researchers. After screening, 64 articles were withheld for our review. Results: The perioperative administration of isotonic fluids is safer than hypotonic solutions, concerning the development of hyponatremia. A balanced isotonic solution with 1-2,5% glucose should be used as perioperative maintenance IV fluid in children (1 month to 18 years). Colloids can be used in children when inadequate effect in volume correction is achieved with crystalloids. The preferred synthetic colloid for children is a third generation HES in a balanced solution. To date, most clinicians use the “4-2-1 rule” for calculating fluid rate. This may not be the optimal fluid rate, as little research has been done. Preoperative fasting for clear fluids should be limited to 1 hour, children should even be encouraged to drink up until 1 hour before induction. Respiratory variation of aortic blood flow peak velocity (ΔVpeak) with echocardiography is currently the most reliable technique for evaluating fluid responsiveness in children.
{"title":"Perioperative fluid management in children: an updated review","authors":"M. Beels, S. Stevens, V. Saldien","doi":"10.56126/73.3.03","DOIUrl":"https://doi.org/10.56126/73.3.03","url":null,"abstract":"Background: Perioperative fluid management in children has been a major topic for debate.\u0000\u0000Objectives: Our aim is to review the current evidence on perioperative fluid management in children including: type of fluid, administration rates, preoperative fluid intake and monitoring techniques.\u0000\u0000Design: Narrative review.\u0000\u0000Method: Following the PRISMA-S guidelines we performed a search (2010-March 2022) in databases Medline (through PubMed) and Cochrane Library. 4297 citations were found and screened by two independent researchers. After screening, 64 articles were withheld for our review.\u0000\u0000Results: The perioperative administration of isotonic fluids is safer than hypotonic solutions, concerning the development of hyponatremia. A balanced isotonic solution with 1-2,5% glucose should be used as perioperative maintenance IV fluid in children (1 month to 18 years). Colloids can be used in children when inadequate effect in volume correction is achieved with crystalloids. The preferred synthetic colloid for children is a third generation HES in a balanced solution. To date, most clinicians use the “4-2-1 rule” for calculating fluid rate. This may not be the optimal fluid rate, as little research has been done. Preoperative fasting for clear fluids should be limited to 1 hour, children should even be encouraged to drink up until 1 hour before induction. Respiratory variation of aortic blood flow peak velocity (ΔVpeak) with echocardiography is currently the most reliable technique for evaluating fluid responsiveness in children.","PeriodicalId":7024,"journal":{"name":"Acta anaesthesiologica Belgica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42705128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Cognitive aids (CAs) are clinical tools guiding clinical decision-making during critical events in the operating room. They may counteract the adverse effects of stress on the non-technical skills of the attending clinician(s). Although most clinicians acknowledge the importance of CAs, their uptake in clinical practice seems to be lagging behind. This situation has led us to investigate which features of CAs may enhance their uptake. Therefore, in this systematic review we explored the optimums regarding the 1) timing to consult the CA, 2) person consulting the CA, 3) location of the CA in the operating room, 4) CA design (paper vs. electronic), 5) CA lay-out, 6) reader of the CA and 7) if the use of CAs in the form of decision support tools lead to improved outcome. Methods: Seven PICO-questions guided our literature search in 4 biomedical databases (MEDLINE, Embase, Web of Science and Google Scholar). We selected English-language randomized controlled trials (RCTs), observational studies and expert opinions discussing the use of cognitive aids during life-threatening events in the operating theatre. Articles discussing non-urgent or non-operating room settings were excluded. The quality of evidence was evaluated with the Grading of Recommendations Assessment, Development and Evaluation (GRADE). Results: We found 7 RCTs, 14 observational studies and 6 expert opinions. All trials were conducted in a simulation environment. The person who should trigger the use of a cognitive aid and the optimal timing of its initiation, could not be defined by the current literature. The ideal location of the cognitive aids remains also unclear. A favorable lay-out of an aid should be well-structured, standardized and easily readable. In addition, several potentially beneficial design features are described. RCT’s could not demonstrate a possible superiority of either electronic or paper-based aids. Both have their advantages and disadvantages. Furthermore, electronic decision support tools are potentially associated with an enhanced performance of the clinician. Likewise, the presence of a reader was associated with an improved performance of key steps in the management of a critical event. However, it remains unclear who should fulfill this role. Conclusion: Several features of the design or utilization of CAs may play a role in enhancing the uptake of CAs in clinical practice during the management of a critical event in the operating room. However, robust evidence supporting the use of a certain feature over another is lacking.
背景：认知辅助设备（CA）是指导手术室关键事件临床决策的临床工具。它们可以抵消压力对主治临床医生非技术技能的不利影响。尽管大多数临床医生都承认CA的重要性，但它们在临床实践中的应用似乎落后了。这种情况促使我们研究CA的哪些特征可以增强其吸收。因此，在本系统综述中，我们探讨了以下方面的最佳情况：1）咨询CA的时间，2）咨询CA人员，3）CA在手术室的位置，4）CA设计（纸质与电子版），5）CA布局，6）CA读者，7）以决策支持工具的形式使用CA是否能改善结果。方法：7个PICO问题指导我们在4个生物医学数据库（MEDLINE、Embase、Web of Science和Google Scholar）中进行文献检索。我们选择了英语随机对照试验（RCT）、观察性研究和专家意见，讨论了在手术室发生危及生命事件时使用认知辅助工具的问题。讨论非紧急或非手术室设置的文章被排除在外。证据的质量通过建议评估、发展和评估分级（GRADE）进行评估。结果：我们发现了7项随机对照试验、14项观察性研究和6项专家意见。所有试验都是在模拟环境中进行的。目前的文献无法定义应该触发使用认知辅助工具的人及其启动的最佳时机。认知辅助设备的理想位置也不清楚。援助的有利布局应结构良好、标准化且易于阅读。此外，还介绍了几个潜在的有益设计特征。RCT无法证明电子或纸质辅助工具的可能优势。两者各有优缺点。此外，电子决策支持工具可能与临床医生的增强性能相关联。同样，阅读器的存在与关键事件管理中关键步骤的改进性能有关。然而，目前尚不清楚谁应该履行这一职责。结论：在手术室处理重大事件的临床实践中，CA的设计或使用的几个特点可能在提高CA的吸收方面发挥作用。然而，缺乏有力的证据支持使用某个功能而不是另一个功能。
{"title":"The use of cognitive aids in the operating room: a systematic review","authors":"A. Claeys, R. Van den Eynde, S. Rex","doi":"10.56126/73.3.18","DOIUrl":"https://doi.org/10.56126/73.3.18","url":null,"abstract":"Background: Cognitive aids (CAs) are clinical tools guiding clinical decision-making during critical events in the operating room. They may counteract the adverse effects of stress on the non-technical skills of the attending clinician(s). Although most clinicians acknowledge the importance of CAs, their uptake in clinical practice seems to be lagging behind. This situation has led us to investigate which features of CAs may enhance their uptake. Therefore, in this systematic review we explored the optimums regarding the 1) timing to consult the CA, 2) person consulting the CA, 3) location of the CA in the operating room, 4) CA design (paper vs. electronic), 5) CA lay-out, 6) reader of the CA and 7) if the use of CAs in the form of decision support tools lead to improved outcome.\u0000\u0000Methods: Seven PICO-questions guided our literature search in 4 biomedical databases (MEDLINE, Embase, Web of Science and Google Scholar). We selected English-language randomized controlled trials (RCTs), observational studies and expert opinions discussing the use of cognitive aids during life-threatening events in the operating theatre. Articles discussing non-urgent or non-operating room settings were excluded. The quality of evidence was evaluated with the Grading of Recommendations Assessment, Development and Evaluation (GRADE).\u0000\u0000Results: We found 7 RCTs, 14 observational studies and 6 expert opinions. All trials were conducted in a simulation environment. The person who should trigger the use of a cognitive aid and the optimal timing of its initiation, could not be defined by the current literature. The ideal location of the cognitive aids remains also unclear.\u0000\u0000A favorable lay-out of an aid should be well-structured, standardized and easily readable. In addition, several potentially beneficial design features are described.\u0000RCT’s could not demonstrate a possible superiority of either electronic or paper-based aids. Both have their advantages and disadvantages. Furthermore, electronic decision support tools are potentially associated with an enhanced performance of the clinician. Likewise, the presence of a reader was associated with an improved performance of key steps in the management of a critical event. However, it remains unclear who should fulfill this role.\u0000\u0000Conclusion: Several features of the design or utilization of CAs may play a role in enhancing the uptake of CAs in clinical practice during the management of a critical event in the operating room. However, robust evidence supporting the use of a certain feature over another is lacking.","PeriodicalId":7024,"journal":{"name":"Acta anaesthesiologica Belgica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48629462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Franquet, J. Pierart, A. Defresne, S. Joachim, V. Fraipont
Acute respiratory distress syndrome remains an uncommon condition during pregnancy. In patients with severe acute respiratory distress syndrome, when oxygenation or ventilation cannot be supported sufficiently using best practice conventional mechanical ventilation and additional therapies, veno-venous extracorporeal membrane oxygenation may be considered. In the past two decades, there has been increasing adoption of this technique to support adult patients with refractory acute respiratory distress syndrome. However, its use for the management of pregnant women is rare and remains a challenge. This narrative review addresses acute respiratory distress syndrome and its management during pregnancy, and then focuses on indications, contraindications, challenges, potential complications, and outcomes of the use of veno-venous extracorporeal membrane oxygenation for acute respiratory distress syndrome in the pregnant patient.
{"title":"Veno-venous Extracorporeal Membrane Oxygenation for pregnant women with Acute Respiratory Distress Syndrome: a narrative review","authors":"N. Franquet, J. Pierart, A. Defresne, S. Joachim, V. Fraipont","doi":"10.56126/73.3.17","DOIUrl":"https://doi.org/10.56126/73.3.17","url":null,"abstract":"Acute respiratory distress syndrome remains an uncommon condition during pregnancy. In patients with severe acute respiratory distress syndrome, when oxygenation or ventilation cannot be supported sufficiently using best practice conventional mechanical ventilation and additional therapies, veno-venous extracorporeal membrane oxygenation may be considered. In the past two decades, there has been increasing adoption of this technique to support adult patients with refractory acute respiratory distress syndrome. However, its use for the management of pregnant women is rare and remains a challenge. This narrative review addresses acute respiratory distress syndrome and its management during pregnancy, and then focuses on indications, contraindications, challenges, potential complications, and outcomes of the use of veno-venous extracorporeal membrane oxygenation for acute respiratory distress syndrome in the pregnant patient.","PeriodicalId":7024,"journal":{"name":"Acta anaesthesiologica Belgica","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46344442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：