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Periodontal regeneration by minimally invasive procedures and its influence on pulp status. 微创牙周再生及其对牙髓状态的影响。
Pub Date : 2023-04-29 DOI: 10.54589/aol.36/1/53
Stefanía H Caceres, Hernán Bonta, Federico G Galli, Liliana G Sierra, Pablo A Rodríguez, Facundo Caride

Dental pulp and periodontium have different communication routes including, e.g., apical foramen, accessory canals and dentin tubules. Scaling, planing and root surface treatment with ethylenediaminetetraacetic acid (EDTA)-based conditioner are used in regenerative periodontal procedures. Such treatment may generate pathological communication between the two structures due to interruption of the vascular pedicle or migration of bacteria and/or inflammatory byproducts from deep periodontal pockets, which may generate pulp pathology.

Aim: The aim of this study was to evaluate the influence of minimally invasive periodontal regenerative surgery on pulp vitality status in single-rooted and multi-rooted teeth associated to infraosseous defects extending to the middle and apical thirds.

Materials and method: This was a retrospective study on 30 teeth from 14 patients who received care between August 2018 and August 2019 at the postgraduate Department of Specialization in Periodontics of the Buenos Aires University School ofDentistry (FOUBA). Clinical and radiographic endodontic diagnosis was performed 6 months after the minimally invasive regenerative periodontal treatment.

Results: Only two out of the 30 teeth presented changes in pulp status following regenerative periodontal procedure: irreversible pulpitis at 30 days and pulp necrosis at 180 days post-treatment. The rate for risk of change in pulp vitality status was 6.7%. Teeth with grade I and II furcation lesions (n=9) presented no change in pulp status.

Conclusions: Regenerative periodontal surgery had no significant influence on pulp status in single-rooted and multi-rooted teeth with infraosseous defects extending to the level of the middle and apical third.

牙髓与牙周组织有不同的交流途径,包括牙髓的根尖孔、副牙髓管和牙本质小管等。以乙二胺四乙酸(EDTA)为基础的调理剂用于再生牙周手术的洗牙、刨牙和牙根表面处理。由于血管蒂的中断或细菌和/或深层牙周袋的炎症副产物的迁移,这种治疗可能会导致两种结构之间的病理交流,这可能会导致牙髓病理。目的:本研究的目的是评估微创牙周再生手术对延伸至中、尖三分之一骨下缺损的单根和多根牙的牙髓活力状态的影响。材料和方法:这是一项回顾性研究,对2018年8月至2019年8月在布宜诺斯艾利斯大学牙科学院牙周病专业研究生部接受治疗的14名患者的30颗牙齿进行了研究。在微创再生牙周治疗6个月后进行临床和影像学诊断。结果:30颗牙齿中只有2颗在牙周再生手术后出现牙髓状态的改变:治疗后30天出现不可逆的牙髓炎,治疗后180天出现牙髓坏死。牙髓活力状态变化风险率为6.7%。有I级和II级分叉病变的牙齿(n=9)的牙髓状态没有变化。结论:再生牙周手术对骨下缺损延伸至中尖三分之一水平的单根和多根牙的牙髓状态无显著影响。
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引用次数: 0
Effect of photopolymerization time on the microhardness of resin cement beneath feldspathic ceramic. 光聚合时间对长石陶瓷下树脂水泥显微硬度的影响。
Pub Date : 2023-04-29 DOI: 10.54589/aol.36/1/40
María A Lei, Ricardo L Macchi, Mariana Picea

During ceramic veneer luting, resin cement polymerization is performed with interposition of the dental ceramic.

Aim: To evaluate how and how much the photoactivation time affects the Vickers hardness of resin-based cements with interposed ceramic.

Materials and method: A total 24 specimens H mm in diameter and 1 mm thick were made from Paracore White Coltene (PC), Densell Resin Duo Cement (DC), 3MRelyX Veneer (RX) and Coltene Fill Up! (FU), interposing VitablockMarkII (Vita Zahnfabrik) feldspathic ceramic 0.6 mm thick during photoactivation. The materials were polymerized using 100% and 25% of the times indicated by the manufacturers with a Coltolux LED ((Coltene) light with intensity 1200 mW/cm2. Each polymerization time group consisted of three specimens of each material, which were stored dry in darkness at 37 °C for 7 days. Three Vickers microhardness measurements were made on the top and bottom surfaces of each specimen using a Vickers Future Tech FM300 microhardness tester (300 g, 5 s). The values were averaged, and the bottom/top ratios calculated. Results were analyzed by ANOVA. (p<0.05) complemented with multiple comparisons using Tukey's test (p<0.05).

Results: Different photoactivation times were found to have a significant effect on hardness values of the cements evaluated, with significant differences between some of the cements. No statistically significant difference was found for the effect of photoactivation time on bottom/top microhardness ratio in those materials.

Conclusions: Under the experimental conditions employed, it can be concluded that photopolymerization for shorter times and the interposition of restorative material significantly affectpolymerization quality as evaluated by microhardness, but the bottom/top ratio was unaffected by differences in polymerization time.

在烤瓷贴面过程中,树脂水泥聚合是在牙瓷的插入下进行的。目的:探讨光活化时间对陶瓷树脂基水泥维氏硬度的影响。材料和方法:采用Paracore White Coltene (PC)、Densell Resin Duo Cement (DC)、3MRelyX Veneer (RX)和Coltene Fill Up!(FU),在光活化过程中插入0.6 mm厚的VitablockMarkII (Vita Zahnfabrik)长石陶瓷。使用强度为1200mw /cm2的Coltolux LED (Coltene)灯,以制造商指定的100%和25%的时间进行聚合。每个聚合时间组由每种材料的3个标本组成,在37°C的黑暗中干燥保存7天。使用Vickers Future Tech FM300显微硬度计(300 g, 5 s)对每个试样的上下表面进行三次维氏显微硬度测量,取平均值,并计算底/顶比值。结果采用方差分析。结果:不同的光活化时间对胶结物的硬度值有显著影响,部分胶结物之间存在显著差异。光活化时间对材料底/顶显微硬度比的影响无统计学差异。结论:在实验条件下,较短的光聚合时间和修复材料的介入对显微硬度评价的聚合质量有显著影响,但底顶比不受聚合时间的影响。
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引用次数: 0
Clinical and microbiological assessment in a subpopulation of young Argentine patients with severe periodontitis. 阿根廷严重牙周炎年轻患者亚群的临床和微生物学评估。
Pub Date : 2023-04-29 DOI: 10.54589/aol.36/1/24
Constanza Pontarolo, Florencia L Bozza, Federico G Galli, Hernán Bontá, Susana L Molgatini, Facundo Caride, Laura A Gliosca

Aggressive periodontitis (AP) is the most serious entity of periodontal disease (stage III/IV, grade C periodontitis according to the latest classification, 2017).

Aim: to enhance knowledge of periodontal microbiota in AP in native Argentine patients and describe the effect of a combined pharmacologicalmechanical periodontal treatment on clinical and microbiological parameters.

Materials and method: The study analyzed 42 periodontal sites in 11 patients diagnosed with AP. Clinical periodontal parameters were recorded at baseline, 45, 90 and 180 days. Microbiological samples were taken before treatment and at 180 days. PCR was used to determine presence of the periodontopathic bacteria Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Tannerella forsythia (Tf), Treponema denticola (Td), Prevotella intermedia (Pi) and Fusobacterium nucleatum (Fn). Patients underwent periodontal therapy including antibiotics (Amoxicillin 500mg + Metronidazole 250mg; 8hs/7 days), and were reevaluated at 45, 90 and 180 days.

Results: Mean age was 28.4 ± 7.9 years. The initial PCR detected the following frequencies: Aa 14.3%, Pi 61.9%, Pg 71.4%, Tf 81.0%, Fn 95.2% and Td 97.6%. Baseline microbiological samples revealed significantly higher prevalence of Pg over Aa (p=0.012). Clinical parameters improved significantly after treatment (73.8% PS<5 mm; PS, NIC, SS p<0.001). At 180 days, a significant decrease in microbiological detection rates was observed (Fn, Td, Tf, Pi, Aa p<0.05). Aa was no longer detectable while Pg did not decrease significantly (p=0.052). Fn was the only study species detected in 100% (n=11:42) of residual pockets (PS≥5 mm) (p=0.053).

Conclusion: In the initial samples, there was significant prevalence of Pg over Aa. Significant clinical improvement was achieved after the mechanical-pharmacological treatment, with undetectable levels of Aa, while Fn persisted in residual pockets, and Pg was present at most of the treated sites.

侵袭性牙周炎(AP)是最严重的牙周病(根据2017年最新分类,III/IV期,C级牙周炎)。目的:提高对阿根廷本地AP患者牙周微生物群的认识,并描述牙周药物机械联合治疗对临床和微生物参数的影响。材料与方法:本研究分析了11例AP患者的42个牙周部位,分别记录了基线、45、90和180天的临床牙周参数。在治疗前和治疗180天分别采集微生物样本。采用PCR检测牙周病细菌放线菌聚合杆菌(Aa)、牙龈卟啉单胞菌(Pg)、连翘Tannerella forsythia (Tf)、密螺旋体(Td)、中间普氏菌(Pi)和核梭杆菌(Fn)的存在情况。患者接受牙周治疗包括抗生素(阿莫西林500mg +甲硝唑250mg;8小时/7天),并在45、90和180天重新评估。结果:平均年龄28.4±7.9岁。初始PCR检测频率为:Aa 14.3%, Pi 61.9%, Pg 71.4%, Tf 81.0%, Fn 95.2%, Td 97.6%。基线微生物样本显示Pg的患病率明显高于Aa (p=0.012)。治疗后临床参数明显改善(73.8%)。结论:在初始样本中,Pg的患病率明显高于Aa。机械药物治疗后,患者的临床表现明显改善,Aa水平未检测到,而Fn持续存在于残余口袋中,Pg存在于大多数治疗部位。
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引用次数: 0
Postoperative pain after third molar extraction surgery in patients with and without bruxism: an observational study. 有磨牙和无磨牙患者第三磨牙拔牙术后疼痛:一项观察性研究。
Pub Date : 2023-04-29 DOI: 10.54589/aol.36/1/47
Olavo A Brilhante-Neto, Caio M Mesquita, Marcelo Dma Costa, Luiz R Paranhos, Danilo L Ciotti, Rogério Hl Motta, Juliana C Ramacciato

Third molar extraction surgery is a frequentprocedure in dentistry. Like any surgical procedure, it may lead to inflammatory responses, and postoperative pain is one of its main complications. Furthermore, temporomandibular disorder (TMD) is a collective termfor several clinicalproblems involving orofacial structures. Patients withparafunction are more sensitive to mechanical stimuli such as pressure during surgical procedures.

Aim: To analyze postoperative pain in patients with and without bruxism subjected to third molar extraction surgery.

Materials and method: This was an observational study including four groups with a 1:1:1:! allocation ratio, conducted following ethical approval. Patients classified as ASA I with an indication for lower third molar extraction were recruited. Bruxism was self-reported. Two surgical techniques were used: one with only forceps and levers (ST1) and another with osteotomy and odontosection (ST2).

Results: Four groups (bruxism and surgical techniques) were enrolled, each with a convenience sample (n=34). Postoperative pain levels were higher in patients with than without bruxism (p<0.05). The comparison between surgical techniques showed significantly higher pain levels only on the seventh day for ST2 groups (p<0.05). Oral mucosaflap incisions did not cause significantly higher persistence and pain levels.

Conclusions: Bruxism, osteotomy, and odontosection may have increased postoperative pain levels, whereas performing an oral mucosa flap did not cause significant differences. Nevertheless, these preliminary data should be interpreted carefully. Randomized controlled trials are required to reinforce the findings of this study.

第三磨牙拔除手术是牙科中常见的手术。像任何外科手术一样,它可能导致炎症反应,术后疼痛是其主要并发症之一。此外,颞下颌紊乱(TMD)是涉及口腔面部结构的几种临床问题的总称。功能障碍患者在手术过程中对机械刺激(如压力)更敏感。目的:分析有磨牙症和无磨牙症患者第三磨牙拔牙术后疼痛情况。材料和方法:这是一项观察性研究,包括四组,1:1:1:!分配比例,按照道德标准进行。纳入ASA I级并有下第三磨牙拔除指征的患者。磨牙症是自我报告的。采用两种手术技术:一种是仅使用钳和杠杆(ST1),另一种是截骨和牙切断术(ST2)。结果:共入组四组(磨牙症组和手术技术组),每组有方便样本(n=34)。有磨牙的患者术后疼痛水平高于无磨牙的患者(结论:磨牙、截骨和牙切开术可能会增加术后疼痛水平,而进行口腔黏膜瓣手术则没有显著差异。然而,这些初步数据应该仔细解释。需要随机对照试验来加强本研究的发现。
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引用次数: 0
Influence of pigment Solutions on color stability and surface properties in low-shrinkage and conventional composites. 颜料溶液对低收缩和常规复合材料颜色稳定性和表面性能的影响。
Pub Date : 2023-04-29 DOI: 10.54589/aol.36/1/58
Luciana L Meneghel, Ana Pp Fugolin, Sandrine B Berger, Américo B Correr, Delise Pellizzaro, Karen Bp Fernandes, Guilherme Genovez-Júnior, Alian If Piauilino, Ricardo D Guiraldo

Color stability is among the most frequent causes of restoration failures, and influences surface properties.

Aim: The aim of this study was to investigate the influence of pigment solutions on low-shrinkage and conventional composites regarding changes in the physical properties of composite surfaces.

Materials and method: Specimens of four composites (Filtek Z350 XT, Point 4, N'Durance and Venus Diamond) were randomly distributed into three groups to be submitted to each of three pigment solutions (red wine, tomato sauce and coffee) in fifteen-minute daily cycles, for twenty-eight days. There were 12 groups altogether (n = 10). Color, surface roughness and hardness tests were performed. Statistical analysis includedAnalysis of variance (ANOVA) and Tukey's significance test (a = 0.05).

Results: Color changes caused by the solutions did not differ significantly among Filtek Z350 XT, Venus Diamond and N'Durance. Hardness decreased significantly in Filtek Z350 XT and Venus Diamond after chemical challenge with each solution. For the composite independent factor, roughness was highest in Venus Diamond, followed by Filtek Z350 XT, Point 4 and N'Durance.

Conclusions: Treatment with different pigment solutions (red wine, tomato sauce or coffee) increased stainability and decreased hardness of both low-shrinkage and conventional composites, while roughness was unaffected.

颜色稳定性是修复失败最常见的原因之一,并影响表面性能。目的:本研究的目的是研究低收缩和常规复合材料中颜料溶液对复合材料表面物理性能的影响。材料和方法:将四种复合材料(Filtek Z350 XT、Point 4、N'Durance和Venus Diamond)的样品随机分为三组,每天15分钟,连续28天,分别放入三种色素溶液(红酒、番茄酱和咖啡)中。共12组(n = 10)。进行了颜色、表面粗糙度和硬度测试。统计分析包括方差分析(ANOVA)和Tukey显著性检验(a = 0.05)。结果:Filtek Z350 XT、Venus Diamond和N'Durance三种溶液引起的颜色变化无显著差异。每种溶液对Filtek Z350 XT和Venus Diamond进行化学处理后,硬度显著降低。对于复合独立因素,金星钻石的粗糙度最高,其次是Filtek Z350 XT, Point 4和N'Durance。结论:用不同的色素溶液(红酒、番茄酱或咖啡)处理后,低收缩率和常规复合材料的不染性增加,硬度降低,粗糙度不受影响。
{"title":"Influence of pigment Solutions on color stability and surface properties in low-shrinkage and conventional composites.","authors":"Luciana L Meneghel,&nbsp;Ana Pp Fugolin,&nbsp;Sandrine B Berger,&nbsp;Américo B Correr,&nbsp;Delise Pellizzaro,&nbsp;Karen Bp Fernandes,&nbsp;Guilherme Genovez-Júnior,&nbsp;Alian If Piauilino,&nbsp;Ricardo D Guiraldo","doi":"10.54589/aol.36/1/58","DOIUrl":"https://doi.org/10.54589/aol.36/1/58","url":null,"abstract":"<p><p>Color stability is among the most frequent causes of restoration failures, and influences surface properties.</p><p><strong>Aim: </strong>The aim of this study was to investigate the influence of pigment solutions on low-shrinkage and conventional composites regarding changes in the physical properties of composite surfaces.</p><p><strong>Materials and method: </strong>Specimens of four composites (Filtek Z350 XT, Point 4, N'Durance and Venus Diamond) were randomly distributed into three groups to be submitted to each of three pigment solutions (red wine, tomato sauce and coffee) in fifteen-minute daily cycles, for twenty-eight days. There were 12 groups altogether (n = 10). Color, surface roughness and hardness tests were performed. Statistical analysis includedAnalysis of variance (ANOVA) and Tukey's significance test (a = 0.05).</p><p><strong>Results: </strong>Color changes caused by the solutions did not differ significantly among Filtek Z350 XT, Venus Diamond and N'Durance. Hardness decreased significantly in Filtek Z350 XT and Venus Diamond after chemical challenge with each solution. For the composite independent factor, roughness was highest in Venus Diamond, followed by Filtek Z350 XT, Point 4 and N'Durance.</p><p><strong>Conclusions: </strong>Treatment with different pigment solutions (red wine, tomato sauce or coffee) increased stainability and decreased hardness of both low-shrinkage and conventional composites, while roughness was unaffected.</p>","PeriodicalId":7033,"journal":{"name":"Acta odontologica latinoamericana : AOL","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2e/03/1852-4834-36-1-58.PMC10283371.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9710977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ozone gas therapy for tooth bleaching preserves enamel microhardness, roughness and surface micromor. 臭氧气体治疗牙齿漂白可以保持牙釉质的显微硬度、粗糙度和表面微细度。
Pub Date : 2023-04-29 DOI: 10.54589/aol.36/1/15
Rafael R Carvalho, Natália R Carlos, Francisco Uf de Campos, Cecilia P Turssi, Waldemir F Vieira Júnior, Flávia Lb do Amaral, Roberta T Basting

After ozone therapy for bleaching, it is important to evaluate enamel surface properties, to ensure thatbleaching provides adequate conditions for sound dental substrate. Aim: The aim of this in vitro studywas to evaluate the effects of a bleaching treatment with 10% carbamide peroxide (CP), with or withoutozone (O), on the microhardness, roughness and micromorphology of the enamel surface.

Materials and method: Bovine enamel blocks were planed and distributed among the following three bleachingtreatment groups (n=10): CP - 1 hour per day/14 days (Opalescence PF 10%/ Ultradent); O - 1 hourper day every 3 days/3 sessions (Medplus V Philozon, 60 mcg/mL and oxygen flow rate of 1 L/min);and OCP - CP with O, 1 hour per day every 3 days/3 sessions. Enamel surface microhardness (Knoop),roughness (Ra), and micromorphology by scanning electron microscopy (5,000x magnification) weredetermined before and after the treatments.

Results: ANOVA and Tukey-Kramer’s test showed thatenamel microhardness remained unchanged by treatment with O and OCP (p=0.0087), but decreasedby treatment with CP. Treatment with O promoted higher enamel microhardness than the other groups(p=0.0169). Generalized linear mixed models for repeated measures over time indicated treatment withCP increased enamel roughness more than OCP or O (p=0.0003). CP produced slight irregularitiesin enamel micromorphology after the whitening treatment. O, with or without CP, maintained themechanical and physical properties of microhardness and enamel surface micromorphology, and eithermaintained or reduced surface roughness, compared to the conventional tray-delivered CP bleachingtreatment.

Conclusions: Treatment with 10% carbamide peroxide in trays promoted greater changesin enamel surface properties than treatments with ozone and with 10% ozonized carbamide peroxidein the office.

在臭氧漂白治疗后,评估牙釉质表面特性是很重要的,以确保漂白为良好的牙基提供足够的条件。目的:本体外研究的目的是评价10%过氧化脲(CP)漂白处理对牙釉质表面的显微硬度、粗糙度和微观形貌的影响。材料和方法:将牛牙釉质块铺成平面,分为3个漂白处理组(n=10): CP -每天1小时/14天(乳白色PF 10%/ Ultradent);O -每天1小时,每3天/3个疗程(Medplus V Philozon, 60 mcg/mL,氧流量1 L/min); OCP - CP,每天1小时,每3天/3个疗程。采用扫描电镜(5000倍放大)测定处理前后牙釉质表面显微硬度(Knoop)、粗糙度(Ra)和显微形貌。结果:方差分析和Tukey-Kramer 's检验显示,O和OCP处理后牙釉质显微硬度没有变化(p=0.0087),而CP处理后牙釉质显微硬度降低(p=0.0169)。随时间重复测量的广义线性混合模型表明,cp治疗比OCP或O治疗更能增加牙釉质粗糙度(p=0.0003)。CP美白处理后牙釉质微形态有轻微的不规则性。与传统的托盘CP漂白处理相比,使用或不使用CP,保持了微硬度和牙釉质表面微观形貌的机械和物理特性,并保持或降低了表面粗糙度。结论:在牙盘中使用10%过氧化脲处理比使用臭氧和10%臭氧过氧化脲处理对牙釉质表面性能的影响更大。
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引用次数: 0
Update on the treatment of chemotherapy and radiotherapy-induced buccal mucositis: a systematic review. 化疗和放疗引起的口腔黏膜炎的治疗进展:一项系统综述。
Pub Date : 2023-04-29 DOI: 10.54589/aol.36/1/3
Schilin Wen, Leonardo Brito, Javiera Santander, Gonzalo Conteras

Oral mucositis (OM) is a frequent complication in cancer patients who are undergoing chemotherapyor radiotherapy. It manifests as an inflammation of the oral mucosa, sometimes provoking severeconsequences such as eating limitations, difficulty in speaking, and possibly superinfection.

Aim: The aim of this review was to update the evidence published during the last five years on the treatment oforal mucositis induced by radiotherapy and/or chemotherapy in patients with cancer.

Materials and method: A search was conducted in Pubmed, Scielo and Scopus, using the search terms mucositis,stomatitis, therapy, treatment, oral cancer, oral squamous cell carcinoma, head and neck cancer andhead and neck carcinoma, with Mesh terms and free terms, from 2017 to January 2023. The systematicreview was conducted in accordance with the PRISMA guidelines.

Results: A total 287 articles wereretrieved, of which 86 were selected by title and abstract, and 18 were included after full-text analysis.The most frequently assessed variables were OM severity, pain intensity and healing time. Treatmenttypes were diverse, and included drugs, mouthwashes, medicines based on plant extracts, cryotherapyand low-intensity laser therapies.

Conclusion: Dentoxol mouthwashes, Plantago major extract, thymehoney extract, zinc oxide paste, vitamin B complex combined with GeneTime, and the consumption ofL-glutamine are effective in diminishing the severity of OM. Pain intensity was lower with doxepinmouthwashes and diphenhydramine-lidocaine-antacid mouthwashes.

口腔黏膜炎(OM)是癌症患者在接受化疗或放疗时常见的并发症。它表现为口腔黏膜的炎症,有时会引起严重的后果,如饮食限制,说话困难,并可能重复感染。目的:本综述的目的是更新近五年来发表的关于癌症患者放疗和/或化疗引起的口腔黏膜炎治疗的证据。材料和方法:检索Pubmed、Scielo和Scopus,检索词为粘膜炎、口炎、治疗、治疗、口腔癌、口腔鳞状细胞癌、头颈癌和头颈癌,检索时间为2017年至2023年1月,检索词为网状词和自由词。系统审查是按照PRISMA指南进行的。结果:共检索到论文287篇,其中按标题和摘要筛选出86篇,经全文分析后纳入18篇。最常评估的变量是OM的严重程度、疼痛强度和愈合时间。治疗方式多种多样,包括药物、漱口水、基于植物提取物的药物、冷冻疗法和低强度激光疗法。结论:Dentoxol漱口水、车前草提取物、百里香蜂蜜提取物、氧化锌膏、复合维生素B联合GeneTime和服用l -谷氨酰胺可有效减轻OM的严重程度。多塞平漱口水和苯海拉明-利多卡因-抗酸漱口水的疼痛强度较低。
{"title":"Update on the treatment of chemotherapy and radiotherapy-induced buccal mucositis: a systematic review.","authors":"Schilin Wen,&nbsp;Leonardo Brito,&nbsp;Javiera Santander,&nbsp;Gonzalo Conteras","doi":"10.54589/aol.36/1/3","DOIUrl":"https://doi.org/10.54589/aol.36/1/3","url":null,"abstract":"<p><p>Oral mucositis (OM) is a frequent complication in cancer patients who are undergoing chemotherapy\u0000or radiotherapy. It manifests as an inflammation of the oral mucosa, sometimes provoking severe\u0000consequences such as eating limitations, difficulty in speaking, and possibly superinfection.</p><p><strong>Aim: </strong>The aim of this review was to update the evidence published during the last five years on the treatment of\u0000oral mucositis induced by radiotherapy and/or chemotherapy in patients with cancer.</p><p><strong>Materials and method: </strong>A search was conducted in Pubmed, Scielo and Scopus, using the search terms mucositis,\u0000stomatitis, therapy, treatment, oral cancer, oral squamous cell carcinoma, head and neck cancer and\u0000head and neck carcinoma, with Mesh terms and free terms, from 2017 to January 2023. The systematic\u0000review was conducted in accordance with the PRISMA guidelines.</p><p><strong>Results: </strong>A total 287 articles were\u0000retrieved, of which 86 were selected by title and abstract, and 18 were included after full-text analysis.\u0000The most frequently assessed variables were OM severity, pain intensity and healing time. Treatment\u0000types were diverse, and included drugs, mouthwashes, medicines based on plant extracts, cryotherapy\u0000and low-intensity laser therapies.</p><p><strong>Conclusion: </strong>Dentoxol mouthwashes, Plantago major extract, thyme\u0000honey extract, zinc oxide paste, vitamin B complex combined with GeneTime, and the consumption of\u0000L-glutamine are effective in diminishing the severity of OM. Pain intensity was lower with doxepin\u0000mouthwashes and diphenhydramine-lidocaine-antacid mouthwashes.</p>","PeriodicalId":7033,"journal":{"name":"Acta odontologica latinoamericana : AOL","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/97/f5/1852-4834-36-1-03.PMC10283397.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9707548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The potential of salivary albumin to degrade composite resin. 唾液白蛋白降解复合树脂的潜力。
Pub Date : 2023-04-29 DOI: 10.54589/aol.36/1/34
Leonardo S Barros, Giovanna C Denucci, Flávia Lb Amoral, Fabiana Mg Franga, Roberta T Basting, Cecilia P Turssi

Albumin is a salivary enzyme capable of cleaving ester linkages and catalyzing degradation of resin-based dental materials. However, the effect of concentration-dependent esterolytic action on composite resins as yet remains unexplored.

Aim: The purpose of this study was to evaluate whether artificial saliva formulations with different concentrations of albumin affected the surface roughness, flexural strength and microhardness of a composite resin.

Materials and method: Specimens (25x2x2mm) of a nanofilled composite (Filtek Z350XT, 3M/ESPE) were prepared and analyzed for average surface roughness (Ra/pm). The specimens were then allocated to 6 groups (n=30), to be treated with different salivary albumin concentrations: 0, 10, 50, 100, 200, 400 pg/mL. The specimens were stored in their respective artificial saliva groups, half of them for 24 h and the remainder for 180 days (artificial saliva renewed weekly), after which they were submitted to a new Ra reading, and tested for three-point flexural strength (FS, MPa). The specimens stored for 180 days were analyzed for Knoop microhardness (KH, Kg/mm2). Data were submitted to two-way ANOVA (Ra and FS) and one-way ANOVA (KH).

Results: Although Ra increased (p < 0.001) and FS decreased (p < 0.001) from 24 hours to 180 days of storage, the albumin concentration did not significantly affectRa (p = 0.168), FS (p = 0.477) or KH (p = 0.378).

Conclusion: The esterolytic action of albumin did not increase the artificial-saliva-induced hydrolytic degradation of the composite resin.

白蛋白是一种唾液酶,能够切断酯键并催化树脂基牙科材料的降解。然而,浓度依赖性的酯水解作用对复合树脂的影响仍未被探索。目的:本研究的目的是评估不同浓度白蛋白的人工唾液配方是否影响复合树脂的表面粗糙度、抗弯强度和显微硬度。材料和方法:制备纳米填充复合材料(Filtek Z350XT, 3M/ESPE)的试样(25x2x2mm),分析其平均表面粗糙度(Ra/pm)。将标本分为6组(n=30),分别给予0、10、50、100、200、400 pg/mL不同浓度的唾液白蛋白处理。将标本分别保存在各自的人工唾液组中,其中一半保存24 h,其余保存180天(每周更新人工唾液),之后提交新的Ra读数,并进行三点抗弯强度(FS, MPa)测试。保存180 d的标本进行Knoop显微硬度(KH, Kg/mm2)分析。数据进行双向方差分析(Ra和FS)和单向方差分析(KH)。结果:贮藏24 ~ 180 d, Ra升高(p < 0.001), FS降低(p < 0.001),但白蛋白浓度对tra (p = 0.168)、FS (p = 0.477)、KH (p = 0.378)无显著影响。结论:白蛋白的酯解作用不增加人工唾液诱导的复合树脂水解降解。
{"title":"The potential of salivary albumin to degrade composite resin.","authors":"Leonardo S Barros,&nbsp;Giovanna C Denucci,&nbsp;Flávia Lb Amoral,&nbsp;Fabiana Mg Franga,&nbsp;Roberta T Basting,&nbsp;Cecilia P Turssi","doi":"10.54589/aol.36/1/34","DOIUrl":"https://doi.org/10.54589/aol.36/1/34","url":null,"abstract":"<p><p>Albumin is a salivary enzyme capable of cleaving ester linkages and catalyzing degradation of resin-based dental materials. However, the effect of concentration-dependent esterolytic action on composite resins as yet remains unexplored.</p><p><strong>Aim: </strong>The purpose of this study was to evaluate whether artificial saliva formulations with different concentrations of albumin affected the surface roughness, flexural strength and microhardness of a composite resin.</p><p><strong>Materials and method: </strong>Specimens (25x2x2mm) of a nanofilled composite (Filtek Z350XT, 3M/ESPE) were prepared and analyzed for average surface roughness (Ra/pm). The specimens were then allocated to 6 groups (n=30), to be treated with different salivary albumin concentrations: 0, 10, 50, 100, 200, 400 pg/mL. The specimens were stored in their respective artificial saliva groups, half of them for 24 h and the remainder for 180 days (artificial saliva renewed weekly), after which they were submitted to a new Ra reading, and tested for three-point flexural strength (FS, MPa). The specimens stored for 180 days were analyzed for Knoop microhardness (KH, Kg/mm<sup>2</sup>). Data were submitted to two-way ANOVA (Ra and FS) and one-way ANOVA (KH).</p><p><strong>Results: </strong>Although Ra increased (p < 0.001) and FS decreased (p < 0.001) from 24 hours to 180 days of storage, the albumin concentration did not significantly affectRa (p = 0.168), FS (p = 0.477) or KH (p = 0.378).</p><p><strong>Conclusion: </strong>The esterolytic action of albumin did not increase the artificial-saliva-induced hydrolytic degradation of the composite resin.</p>","PeriodicalId":7033,"journal":{"name":"Acta odontologica latinoamericana : AOL","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/59/22/1852-4834-36-1-34.PMC10283366.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9708347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of different toothpastes on permeability and roughness of eroded dentin. 不同牙膏对侵蚀牙本质渗透性和粗糙度的影响。
Pub Date : 2022-12-31 DOI: 10.54589/aol.35/3/229
Fernanda Ss Ramos, Alberto Cb Delbem, Paulo H Dos Santos, Mariana D Moda, André Lf Briso, Ticiane C Fagundes

Dentin hypersensitivity (DH) is characterized by rapid, acute pain arising from exposed dental tubules.

Aim: the aim of this study was to evaluate the roughness, tubule occlusion, and permeability of eroded dentin brushed with different toothpastes.

Materials and method: ninety bovine teeth were cut into blocks. Thirty hemifaces were protected with varnish and the other sixty were submitted to permeability tests. Specimens were divided into groups according to the dentifrices: without fluoride (WF), sodium fluoride (NaF), and stannous fluoride (SnF2). The blocks were subjected to a 5-day erosive-abrasive protocol. Surface roughness and dentinal tubule occlusion (n=10) were assessed for both control and test hemifaces of the same sample along with permeability analysis (n=20). Two-way RM ANOVA and Tukey's post-hoc test were performed (p≤0.05).

Results: NaF and SnF2 presented higher roughness than WF. The number of open tubules was higher in WF. Permeability was higher in SnF2, but there was no significant difference between WF and NaF.

Conclusions: both fluoride toothpastes occluded dentinal tubules and increased roughness. NaF toothpaste promoted greater decrease in dentin permeability.

牙本质过敏(DH)的特点是由暴露的牙小管引起的快速急性疼痛。目的:本研究的目的是评估不同牙膏刷牙后牙本质的粗糙度、小管闭塞性和渗透性。材料和方法:将90颗牛牙切成块状。30个侧面涂上清漆,另外60个侧面进行渗透性测试。标本按含牙成分分为无氟组(WF)、氟化钠组(NaF)和氟化亚锡组(SnF2)。这些砌块进行了为期5天的侵蚀磨蚀试验。对同一样品的对照面和测试面进行表面粗糙度和牙本质小管咬合(n=10)评估,并进行渗透性分析(n=20)。进行双向RM方差分析和Tukey事后检验(p≤0.05)。结果:NaF和SnF2的粗糙度高于WF。WF中开放小管数量较多。SnF2的通透性较高,但WF与NaF之间无显著差异。结论:两种含氟牙膏均对牙本质小管造成阻塞,粗糙度增加。NaF牙膏促进了牙本质渗透性的更大下降。
{"title":"Effect of different toothpastes on permeability and roughness of eroded dentin.","authors":"Fernanda Ss Ramos,&nbsp;Alberto Cb Delbem,&nbsp;Paulo H Dos Santos,&nbsp;Mariana D Moda,&nbsp;André Lf Briso,&nbsp;Ticiane C Fagundes","doi":"10.54589/aol.35/3/229","DOIUrl":"https://doi.org/10.54589/aol.35/3/229","url":null,"abstract":"<p><p>Dentin hypersensitivity (DH) is characterized by rapid, acute pain arising from exposed dental tubules.</p><p><strong>Aim: </strong>the aim of this study was to evaluate the roughness, tubule occlusion, and permeability of eroded dentin brushed with different toothpastes.</p><p><strong>Materials and method: </strong>ninety bovine teeth were cut into blocks. Thirty hemifaces were protected with varnish and the other sixty were submitted to permeability tests. Specimens were divided into groups according to the dentifrices: without fluoride (WF), sodium fluoride (NaF), and stannous fluoride (SnF2). The blocks were subjected to a 5-day erosive-abrasive protocol. Surface roughness and dentinal tubule occlusion (n=10) were assessed for both control and test hemifaces of the same sample along with permeability analysis (n=20). Two-way RM ANOVA and Tukey's post-hoc test were performed (p≤0.05).</p><p><strong>Results: </strong>NaF and SnF2 presented higher roughness than WF. The number of open tubules was higher in WF. Permeability was higher in SnF2, but there was no significant difference between WF and NaF.</p><p><strong>Conclusions: </strong>both fluoride toothpastes occluded dentinal tubules and increased roughness. NaF toothpaste promoted greater decrease in dentin permeability.</p>","PeriodicalId":7033,"journal":{"name":"Acta odontologica latinoamericana : AOL","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/80/a1/1852-4834-35-3-229.PMC10283392.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9703171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bonding strategy of a universal adhesive system containing chitosan: influence on dentin permeability, and effect on adhesive layer micromorphology. 壳聚糖万能粘结体系的粘结策略:对牙本质渗透性的影响及对粘结层微观形貌的影响。
Pub Date : 2022-12-31 DOI: 10.54589/aol.35/3/206
Henrique Eg Bettiol, Waldemir F Vieira-Junior, Fabiana Mg França, Flávia Lb Amaral, Roberta T Basting

Aim: This study evaluated the influence of chitosan added to a universal adhesive system used in totaletch (TE) or self-etch (SE) mode on dentin permeability, and on the micromorphology of the adhesive layer.

Materials and method: Dentin discs were obtained from human third molars and randomly distributed according to bonding strategy (TE or SE), and to whether or not 1% chitosan (C) was added to a universal adhesive system (Single Bond Universal/3M ESPE), to create the following groups (n=10): TE, TEC, SE, and SEC. Dentin permeability was measured at baseline and after application of dentin treatments. The surface of the adhesive layer (AL) and the dentin adjacent to the AL were examined under a scanning electron microscope.

Results: There were no significant differences in permeability percentage between the groups with and without C (TE and SE versus TEC and SEC) (p>0.05; Mann Whitney test). Dentin permeability was lower when the adhesive system was applied in the SE mode, regardless of the addition of C. The micromorphology of the AL surface showed irregularities, and a greater degree of porosity, when the adhesive system was applied in the SE mode, regardless of chitosan addition. There was a greater depth of penetration of the adhesives into the dentin adjacent to the AL in both the TE and TEC groups. Chitosan added to the adhesive system did not influence dentin permeability.

Conclusions: The self-etch strategy led to lower dentin permeability, and to more irregularities on the surface of the adhesive layer.

目的:研究在全蚀(TE)和自蚀(SE)模式下添加壳聚糖对牙本质渗透性和粘接层微观形貌的影响。材料和方法:从人类第三磨牙中取出牙本质盘,根据粘接策略(TE或SE)以及是否在通用粘接系统(Single Bond universal /3M ESPE)中添加1%壳聚糖(C)随机分布,分为以下组(n=10): TE、TEC、SE和SEC。在基线和应用牙本质处理后测量牙本质渗透率。扫描电镜下观察粘附层(AL)表面及与AL相邻的牙本质。结果:加C组与不加C组(TE、SE组与TEC、SEC组)通透率差异无统计学意义(p>0.05;曼-惠特尼试验)。无论是否添加壳聚糖,在SE模式下应用胶黏剂体系时,牙本质渗透性较低。无论是否添加壳聚糖,在SE模式下应用胶黏剂体系时,AL表面的微观形貌表现出不规则性,孔隙度更大。在TE组和TEC组中,粘接剂对临近AL的牙本质的渗透深度都更大。粘接体系中添加壳聚糖对牙本质渗透性无影响。结论:自蚀策略导致牙本质渗透性降低,粘接层表面不规则性增加。
{"title":"Bonding strategy of a universal adhesive system containing chitosan: influence on dentin permeability, and effect on adhesive layer micromorphology.","authors":"Henrique Eg Bettiol,&nbsp;Waldemir F Vieira-Junior,&nbsp;Fabiana Mg França,&nbsp;Flávia Lb Amaral,&nbsp;Roberta T Basting","doi":"10.54589/aol.35/3/206","DOIUrl":"https://doi.org/10.54589/aol.35/3/206","url":null,"abstract":"<p><strong>Aim: </strong>This study evaluated the influence of chitosan added to a universal adhesive system used in totaletch (TE) or self-etch (SE) mode on dentin permeability, and on the micromorphology of the adhesive layer.</p><p><strong>Materials and method: </strong>Dentin discs were obtained from human third molars and randomly distributed according to bonding strategy (TE or SE), and to whether or not 1% chitosan (C) was added to a universal adhesive system (Single Bond Universal/3M ESPE), to create the following groups (n=10): TE, TEC, SE, and SEC. Dentin permeability was measured at baseline and after application of dentin treatments. The surface of the adhesive layer (AL) and the dentin adjacent to the AL were examined under a scanning electron microscope.</p><p><strong>Results: </strong>There were no significant differences in permeability percentage between the groups with and without C (TE and SE versus TEC and SEC) (p>0.05; Mann Whitney test). Dentin permeability was lower when the adhesive system was applied in the SE mode, regardless of the addition of C. The micromorphology of the AL surface showed irregularities, and a greater degree of porosity, when the adhesive system was applied in the SE mode, regardless of chitosan addition. There was a greater depth of penetration of the adhesives into the dentin adjacent to the AL in both the TE and TEC groups. Chitosan added to the adhesive system did not influence dentin permeability.</p><p><strong>Conclusions: </strong>The self-etch strategy led to lower dentin permeability, and to more irregularities on the surface of the adhesive layer.</p>","PeriodicalId":7033,"journal":{"name":"Acta odontologica latinoamericana : AOL","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/50/01/1852-4834-35-3-206.PMC10283365.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9703170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Acta odontologica latinoamericana : AOL
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