Acta Informatica Medica最新文献

Background: In the ever-evolving healthcare landscape, the imperative to ensure patient safety has driven the adoption of robust safety approaches. One of the most popular methods is Healthcare Failure Mode and Effect Analysis (HFMEA).

Objective: This study aims to conduct a bibliometric analysis of HFMEA research in a surgery setting to identify relevant authors, topics, and journals, highlighting the scholarly collaboration trends in this area. This analysis can provide valuable insights into the current state of research, emerging trends, and future research directions.

Methods: The data was acquired online from the PubMed database on December 16th, 2023. The downloaded data were analyzed using Google Sheets to predict trends. The publication output was then analyzed using VOSviewer. Subsequently, Biblioshiny was used to analyze the characteristics of the study, productive author, institution, and country; thematic map analysis; and topic timeline analysis.

Results: This study analyzes 25 documents spanning 2005 to 2022, reflecting a collaborative effort involving 155 contributors. The upward trend in annual scientific publications, notably the surge from 2014 onwards and significant peaks in 2019 and 2022, underscores the growing recognition of HFMEA in enhancing patient safety within surgical environments. The prominent influence from prolific authors like Ahmed K, leading institutions such as King's College London, and the substantial contributions from Norway and the USA in shaping the HFMEA research landscape.

Conclusion: This study contributes valuable insights that can shape the trajectory of HFMEA in the evolving landscape of surgical healthcare, ensuring enhanced patient safety and quality improvement.

Background: The safety of blood products is the most important task of transfusion medicine. Transfusion-transmitted diseases represent a serious public health problem throughout the world, although their percentage of transmission is minimal. Each blood donation is individually tested with serological and molecular tests for the presence of hepatitis B and C viruses, human immunodeficiency virus (HIV), and Treponema Pallidum, regardless of the number of blood donations.

Objective: To determine the seroprevalence of blood-borne diseases in healthy blood donors at the University Clinical Center Tuzla, to analyze the possible causes of transmission of these diseases, and to compare with the results of research in countries in the region and beyond.

Methods: The research was conducted retrospectively in the period January 1, 2018. until 31.12.2022. years. Samples of blood donors were tested for hepatitis B surface antigen (HBsAg), antibodies to human immunodeficiency virus (HIV1/2), antibodies to hepatitis C and syphilis, using the fourth generation ELISA method.

Results: The highest frequency of transmisive disease markers was reactivity to HBsAg with a total of 63.7% of cases and a prevalence of 0.13%, and the lowest for HIV with a total of 1.4% and a prevalence of 0.003%.

Conclusion: Bosnia and Herzegovina has a very low seroprevalence but there is still a risk of disease transmission in the population.

Background: In recent years, there has been a significant focus on the development of artificial intelligence (AI) applications in healthcare. However, current scientific evidence is still not convincing enough for the general public and the medical community to widely adopt AI in clinical practice.

Objective: We conducted this study to investigate the correlation between left ventricular function indices assessed by AI and those evaluated by physicians.

Methods: This cross-sectional descriptive study was conducted on 136 patients who attended and received treatment at Hue University of Medicine and Pharmacy Hospital from April 2022 to June 2023. Using QLAB version 15, Philips Healthcare.

Results: The AI software accurately identified 98.5% of the echocardiographic cine-loops. However, there were about 1.5% of cine-loops that the software failed to recognize. The sensitivity of Ejection Fraction (EF) calculated by AI was 73.3%, specificity was 81.3%, and accuracy stood at 78.6%. A strong positive correlation was observed between EF measured by AI and that assessed by physicians, r = 0.701, p < 0.01. The sensitivity of Global Longitudinal Strain (GLS) calculated by AI was 42.1%, specificity was 84.8%, and accuracy was 67.6%. A moderate positive correlation was found between GLS measured by AI and physician's assessment, r = 0.460, p < 0.01.

Conclusion: The use of AI software for evaluating left ventricular function through ejection fraction and global longitudinal strain is rapid and yields results comparable to cardiologists' echocardiographic assessments. The AI-powered software holds a promising and feasible future in clinical practice.

Background: The use of gadgets for a long duration causes problems related to discomfort and causes various other eye complaints. Online lectures cause students to be more intense in using gadgets to support their learning. Therefore, it is necessary to conduct research on the relationship between decreased visual acuity and the use of gadgets during online lectures during the Covid-19 pandemic.

Objective: Knowing the relationship between decreased visual acuity and the use of gadgets during online in Covid-19 pandemic for students of the Faculty of Medicine, Universitas Sumatera Utara class of 2019 and 2020.

Methods: This research is an analytic research with cross sectional design. The sampling technique used in this study was stratified random sampling, in which 100 respondents were selected using simple random sampling.

Results: There are 100 respondents, 81 of them used gadgets for more than 4 hours in one day, 67 of them used gadgets with a viewing distance of 30 cm to 40 cm, and 91 of them had normal visual acuity.

Conclusion: There is no significant relationship between a decrease in visual acuity and the duration or distance of seeing in the use of gadgets as evidenced by the p-values of 0.653 and 0.095 respectively.

Background: Restrictive measures implemented by governments around the world to control the coronavirus have an impact on communication, especially the communication of the elderly.

Objective: The aim for the article is to determine the attitudes of the elderly towards the ways of communication during the COVID 19 pandemic, and to present the challenges faced by the elderly when using digital ways of communication. The goal is also to point out the importance of providing adequate social support to the elderly.

Methods: The sample consisted of 71 respondents from Bosnia and Herzegovina, aged over 60 years, divided into two groups. The questionnaire was used to gather information from respondents on their demographic characteristics as well as to examine participants' attitudes and confidence regarding the manner and risk of communication associated with COVID-19.

Results and discussion: The results of this research showed that the elderly are actively using digital technologies, but that they are largely dissatisfied with their skills in using digital technologies. Most of the information during the COVID 19 pandemic is given to elderly people via television and telephone (video) conversations with family members and friends. 57.7% of the elderly stated that they greatly lacked direct communication, and it turned out that people living in elderly homes were in a slightly more favorable position. As many as 4/5 of the respondents reported feelings of anxiety, fear, loneliness, and depression.

Conclusion: The older part of the population (those over 60 years old), especially in developing countries, including Bosnia and Herzegovina, is facing the challenge of "digitization of communication". In the context of the COVID-19 pandemic, the elderly are "calling" for special support and the provision of training and access to technological resources in order to reduce negative psychological consequences and go one step further in creating an "elder-friendly" society.

Background: Retinitis pigmentosa (RP) is a set of inherited rod-cone degenerative diseases that clinically presents with similar signs and symptoms. Mutations in one of more than 70 genes are involved. Patients will commonly present with bone-spicule pigment formation, waxy optic nerve pallor, and attenuated blood vessels in the posterior pole.Symptoms often begin with progressive night blindness, mid-peripheral visual field defects, and eventual tunnel vision. Central vision loss will ultimately occur following loss of rod function. Complete blindness is uncommon.

Objective: The aim of this article is to present two cases of retinitis pigmentosa (mother and daughter) trough optalmologic exams in our clinic. The next aim it to show how to menage a low vision service and to treat cystoid macular oedema as a complication of retinitis pigmentosa.

Methods: All medical reports are shown in this article. Every diagnostic tool as well as report is a part from our archived history of the patients and has been throughly analysed. We also reviewed available literature using the key words retinitis pigmentosa, cystoid macular oedema, gene therapy.

Case presentation: A 38 year old female patient for a low vision consultation. The patient was legally blind secondary to retinitis pigmentosa, which was diagnosed in her late 20s. She reported gradually progressive hazy central vision and decreasing peripheral vision in both eyes as well as severe night blindness. Other than the diagnosis of retinitis pigmentosa in both eyes,the patient had no other remarkable ocular conditions. Findings at that visit included unaided distance visual acuities VOD: 0,04 VOS: 0,06. Pupils were round with brisk responses. Extraocular muscle motility was full in both eyes. Confrontation methode visual fields were noted as temporal loss in the right eye and superior and temporal loss in the left eye. The perimetry test could not be performed due to the lack of correspondece of the patient even after a couple repetitions of the perimetry. She had normal ocular adnexa and quiet lids, conjunctiva, and sclera in both eyes. Corneas in both eyes were noted as clear epithelium, clear stroma, and clear endothelium. Anterior chambers had normal depth, iris with no pathological findings in both eyes; lens incipient sclerotic. Intraocular pressures were noted as 22 mmHg in both eyes with Icare, 21mmHg and 19 mmHg with aplanation tonometry; pahimetry corretional factor was +1 on both eyes. The vitreous was clear in both eyes. Both optic nerves were measured as 0.4 cup-to-disc ratios with no disc edema, disc hemorrhages, notching, or thinning noted.Waxy disc pallor and attenuated blood vessels were observed in both eyes. The macula in both eyes had retinal pigment epithelium (RPE) changes with no edema or hemorrhages. Bone spicule changes were noted 360 in the periphery of both eyes with no holes or tears(Figu

Background: An important global public health problem in many economically developed countries, in particular in Kazakhstan, is the leading cause of morbidity and mortality from cardiovascular disease (CVD), both in urban and rural areas.

Objective: This study aims to develop the design of a mobile application for smartphones for cardiac patients, taking into account the specifics of outpatient care.

Methods: This methodological study includes identified educational and prevention content for CVD patients to develop an education and monitoring tool using a smartphone app. The application was developed according to the stages of analysis, design, development, implementation and evaluation, which is a systematic training model of design. The levels of satisfaction with the developed application for smartphones among 65 outpatients with CVD were assessed using a questionnaire during their visit to a medical organization.

Results: The «My Heart» smartphone app was developed based on a review of the literature related to educating patients with CVD, consulting specialists, monitoring and searching for medical smartphone applications that are already available. The content of education and registration includes three main sections, containing basic questions on registration and monitoring of the condition, materials on education and prevention of CVD, such as a daily questionnaire and nutritional advice. After modification based on expert feedback, the application was finally developed and evaluated by patients who reported being satisfied with the usefulness of the application.

Conclusions: This application is developed as a research tool to further conduct a study in CVD patients. Current evaluation was a pilot testing wherein this application showed promising results.

Background: COVID-19 pandemic has created many challenges for clinicians. The monitoring trend for laboratory biomarkers is helpful to provide additional information to determine the role of those in the severity status and death outcome.

Objective: This article aimed to evaluate the time-varying biomarkers by LOWESS Plot, check the proportional hazard assumption, and use to extended Cox model if it is violated.

Methods: In the retrospective study, we evaluated a total of 1641 samples of confirmed patients with COVID-19 from October until March 2021 and referred them to the central hospital of Ayatollah Rohani Hospital affiliated with Babol University of medical sciences, Iran. We measured four biomarkers AST, LDH, NLR, and lymphocyte in over the hospitalization to find out the influence of those on the rate of death of COVID-19 patients.

Results: The standard Cox model suggested that all biomarkers were prognostic factors of death (AST: HR=2.89, P<0.001, Lymphocyte: HR=2.60, P=0.004, LDH: HR=2.60, P=0.006, NLR: HR=1.80, P<0.001). The additional evaluation showed that the PH assumption was not met for the NLR biomarker. NLR biomarkers had a significant time-varying effect, and its effect increase over time (HR(t)=exp (0.234+0.261×log(t)), p=0.001). While the main effect of NLR did not show any significant effect on death outcome (HR=1.26, P=0.097).

Conclusion: The reversal of results between the Cox PH model and the extended Cox model provides insight into the value of considering time-varying covariates in the analysis, which can lead to misleading results otherwise.

In the hilly Balkans, a folk proverb has been circulating for a long time, "It is most difficult to be a prophet in one's own village", which reflects the age-old mistrust of the population towards new ideas. This is not surprising in the least, because since the written history of the peoples of the Balkans has existed, a continuous series of conquerors and local rulers who subjugated the common folks and imposed their world view can be traced. Nevertheless, from time to time, people with great strength appear who not only break the shackles imposed by the powerful, but through their actions find a way to the souls of their compatriots and gain their unreserved trust. One of such spontaneous creators is professor Izet Mašić, who achieved a miracle of medical publishing in his Sarajevo and Bosnia and Herzegovina and traced the path of medical science. There may be thousands of medical journals in the world, more or less reputable, and researchers from the Balkans can publish their work in them, but only domestic medical journals can initiate and direct domestic medical research, and educate young researchers in the right way. Professor Mašić made it possible for authors from Bosnia and Herzegovina and other Balkan countries to present their results to the world and receive an incentive from impartial experts to continue their work and progress more and more by editing and publishing three domestic journals at once, which are visible in the most important world bases,. The progress in research then translated into improving medical practice and health care of the population. The following details from Professor Mašić's biography tell us how this miracle happened. This year, academician Izet Mašić, Editor-in-Chief of a few biomedical journals, including Acta Informatica Medica journal, celebrates his 70th birthday and also 45 years of his academic and scientific work.

Background: Tuberculosis can cause a substantial challenge against public health, especially in the developing countries which have low level of socio-economic condition that does not support the control over tuberculosis transmission and infection.

Objective: To find a new surveillance model of tuberculosis transmission control based on geographic information system data in improving the tuberculosis transmission control and treatment outcome.

Methods: Effectiveness test of the self-monitoring of calendar documentation on the tuberculosis transmission control and outcome treatment with quasi-experimental post-test only with control group design. The analytical unit consisted of 96 tuberculosis cases as the self-monitoring group of calendar documentation (intervention) and 87 tuberculosis cases as the control group sourced of two different primary health care.

Results: The self-monitoring intervention of calendar documentation increased the average treatment effect on medicines intake control 0.11 (95% CI: 0.01-0.21), environment control 0.32 (95% CI: 0.19-46), droplets nuclei control 0.49 (95% CI: 0.36-0.61), cured 0.22 (95% CI: 0.09-0.36), completed 0.18 (95% CI: 0.09-0.26), drop out 0.09 (95% CI: 0.01-0.16), and failure of treatment 0.18 (95% CI: 0.09-0.26) of the control group (baseline).

Conclusion: The final result of this research found a new surveillance model of tuberculosis transmission control in google earth mapping aplication based on Geographic Information system.