Pub Date : 2021-06-01DOI: 10.5455/aim.2020.28.130-134
I. Masic
Hans Peterson, MD, PhD, FEFMI, FACMI, FIMIA, FIAHSI (1928-2021), became a certified physician in Sweden in 1958 and was awarded a doctorate in Medicine in 1967 (1-4). He was an ophthalmology fellow at the Karolinska Institute, Stockholm University, and was appointed to faculty positions in Ophthalmology and Medical Informatics at the Karolinska in the late 1970’s.
Hans Peterson，医学博士，博士，FEMMI，FACMI，FIMIA，FIAHSI（1928-2021），1958年成为瑞典的注册医生，1967年获得医学博士学位（1-4）。他是斯德哥尔摩大学卡罗琳斯卡研究所的眼科研究员，并于20世纪70年代末被任命为卡罗琳斯卡大学眼科和医学信息学的教员。
{"title":"The Most Influential Scientists in the Development of Medical Informatics (30): Hans Peterson (1928-2021)","authors":"I. Masic","doi":"10.5455/aim.2020.28.130-134","DOIUrl":"https://doi.org/10.5455/aim.2020.28.130-134","url":null,"abstract":"Hans Peterson, MD, PhD, FEFMI, FACMI, FIMIA, FIAHSI (1928-2021), became a certified physician in Sweden in 1958 and was awarded a doctorate in Medicine in 1967 (1-4). He was an ophthalmology fellow at the Karolinska Institute, Stockholm University, and was appointed to faculty positions in Ophthalmology and Medical Informatics at the Karolinska in the late 1970’s.","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"29 1","pages":"134 - 135"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43430499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-06-01DOI: 10.5455/aim.2020.28.145-145
I. Masic
{"title":"The Most Influential Scientists in the Development of Medical Informatics (26): Barry Barber (1933-2019)","authors":"I. Masic","doi":"10.5455/aim.2020.28.145-145","DOIUrl":"https://doi.org/10.5455/aim.2020.28.145-145","url":null,"abstract":"","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"28 1","pages":"144 - 145"},"PeriodicalIF":0.0,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44600827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-01DOI: 10.5455/aim.2019.27.177-180
Alma Biscevic, Maja Bohac, M. Pjano, Senad Grišević, Sudi Patel, Ajla Pidro
Introduction: The WaveLight Allegretto Eye-Q is a flying-spot excimer laser, with a pulse repetition rate of 400Hz, with two galvanometric scanners for positioning laser pulses. The system has an infrared high speed camera operating at 400Hz to track the patient’s eye movements that either compensates for changes in eye position or interrupts the treatment if the eye moves outside a preset predetermined range. Aim: The purpose of this study was to investigate WaveLight Allegretto Eye-Q 400Hz laser delivery platform aimed to correct astigmatism by subjecting the pre and postoperative astigmatic values to vector analysis. Methods: Patients were divided into two groups, depending on the type of astigmatism. Astigmatism was between 2 and 7 diopters (D). A total of 188 eyes (110 patients), 127 eyes (71 patients) with myopic astigmatism and 61 eyes (39 patients) with mixed astigmatism underwent unremarkable LASIK correction on WaveLight Allegretto Eye-Q 400Hz. The preoperative and postoperative sphere, negative cylinder [C] and axis (ø) of manifest refractions were subjected to vector analysis by calculations of the standard J0 (cos [4π(ø-90)/360]xC/2) and J45 (sin[4π(ø-90)/ 360]xC/2). Results: Reporting the key results, we found that J0 significantly reduced after LASIK (p<0.001) but not J45. There was no significant association between individual pairs of pre and postoperative J0 &J45 values. Conclusion: WaveLight Allegretto 400Hz showed excellent results for treating patients with high astigmatism, regardless whether it is mixed or myopic astigmatism. The J45 did not reduce significantly possibly because of the low number of eyes with oblique astigmatism. There was no genuine difference postoperatively between groups treated on WaveLight Allegretto platform according to the vector analyses.
{"title":"Treatment of High Astigmatism with WaveLight Allegretto Eye-Q Excimer Laser Platform","authors":"Alma Biscevic, Maja Bohac, M. Pjano, Senad Grišević, Sudi Patel, Ajla Pidro","doi":"10.5455/aim.2019.27.177-180","DOIUrl":"https://doi.org/10.5455/aim.2019.27.177-180","url":null,"abstract":"Introduction: The WaveLight Allegretto Eye-Q is a flying-spot excimer laser, with a pulse repetition rate of 400Hz, with two galvanometric scanners for positioning laser pulses. The system has an infrared high speed camera operating at 400Hz to track the patient’s eye movements that either compensates for changes in eye position or interrupts the treatment if the eye moves outside a preset predetermined range. Aim: The purpose of this study was to investigate WaveLight Allegretto Eye-Q 400Hz laser delivery platform aimed to correct astigmatism by subjecting the pre and postoperative astigmatic values to vector analysis. Methods: Patients were divided into two groups, depending on the type of astigmatism. Astigmatism was between 2 and 7 diopters (D). A total of 188 eyes (110 patients), 127 eyes (71 patients) with myopic astigmatism and 61 eyes (39 patients) with mixed astigmatism underwent unremarkable LASIK correction on WaveLight Allegretto Eye-Q 400Hz. The preoperative and postoperative sphere, negative cylinder [C] and axis (ø) of manifest refractions were subjected to vector analysis by calculations of the standard J0 (cos [4π(ø-90)/360]xC/2) and J45 (sin[4π(ø-90)/ 360]xC/2). Results: Reporting the key results, we found that J0 significantly reduced after LASIK (p<0.001) but not J45. There was no significant association between individual pairs of pre and postoperative J0 &J45 values. Conclusion: WaveLight Allegretto 400Hz showed excellent results for treating patients with high astigmatism, regardless whether it is mixed or myopic astigmatism. The J45 did not reduce significantly possibly because of the low number of eyes with oblique astigmatism. There was no genuine difference postoperatively between groups treated on WaveLight Allegretto platform according to the vector analyses.","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"27 1","pages":"177 - 180"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44782848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-01DOI: 10.5455/aim.2019.27.162-166
Fikret Veljović, Senad Burak, E. Begić, I. Masic
Introduction: Investigations have shown that noise is one of the etiologic factors that leads to a risk of cardiovascular incidence. Aim: To present effect of noise on arterial tension and heart rate of workers who work on machine press during period of three-years. Methods: The study had a prospective character and included 30 subjects (n = 30) who were monitored over a three-year period (36 months). The respondents worked at the factory “Cimos” on machine press (Zenica, Bosnia and Herzegovina). Ten machine presses were monitored, and three workers worked on each press. Approximately every worker was affected by a wide range of noise between 65 and 110 dB in the workplace (via isohypse). MATLAB (version 9.4, MathWorks, Natick, Massachusetts, United States of America (USA)) software was used to estimate the possible damage caused by noise in factories that produce noise in their work. Results: During the three-year period, arterial tension in the subjects increased, and at the end of the observed period, they were considered as patients with a diagnosis of arterial hypertension grade I. The tension depends on the strength of the produced noise, and the values also depend on position of the respondent on the machine press. Conclusion: Noise prevention has become a problem of modern medicine. The result of our work allows estimation of arterial hypertension in specified time in case of exposure to a certain strength of noise. Prevention of noise, daytime noise prevention as well as better equipment for work and preventive equipment are imposed as imperative in such or similar conditions, with the need of development of national strategies for this issue in countries where they are not present.
{"title":"Noise Effect on Blood Pressure and Heart Rate - Regression Analysis in Service of Prediction","authors":"Fikret Veljović, Senad Burak, E. Begić, I. Masic","doi":"10.5455/aim.2019.27.162-166","DOIUrl":"https://doi.org/10.5455/aim.2019.27.162-166","url":null,"abstract":"Introduction: Investigations have shown that noise is one of the etiologic factors that leads to a risk of cardiovascular incidence. Aim: To present effect of noise on arterial tension and heart rate of workers who work on machine press during period of three-years. Methods: The study had a prospective character and included 30 subjects (n = 30) who were monitored over a three-year period (36 months). The respondents worked at the factory “Cimos” on machine press (Zenica, Bosnia and Herzegovina). Ten machine presses were monitored, and three workers worked on each press. Approximately every worker was affected by a wide range of noise between 65 and 110 dB in the workplace (via isohypse). MATLAB (version 9.4, MathWorks, Natick, Massachusetts, United States of America (USA)) software was used to estimate the possible damage caused by noise in factories that produce noise in their work. Results: During the three-year period, arterial tension in the subjects increased, and at the end of the observed period, they were considered as patients with a diagnosis of arterial hypertension grade I. The tension depends on the strength of the produced noise, and the values also depend on position of the respondent on the machine press. Conclusion: Noise prevention has become a problem of modern medicine. The result of our work allows estimation of arterial hypertension in specified time in case of exposure to a certain strength of noise. Prevention of noise, daytime noise prevention as well as better equipment for work and preventive equipment are imposed as imperative in such or similar conditions, with the need of development of national strategies for this issue in countries where they are not present.","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"27 1","pages":"162 - 166"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43126839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-01DOI: 10.5455/aim.2019.27.181-185
Amra Džananović, A. Begić, D. Pokrajac
Introduction: Congenital hydronephrosis (CH) is a condition with dilated renal pelvis with or without dilation of renal calyces. Aim: To examine the role of magnetic resonance urography in the detection of congenital hydronephrosis in comparison to dynamic renal scintigraphy (DRS). Patients and methods: Resarch included 58 (n=58) patients with diagnosis of congenital unilateral or bilateral dilatation of kidney duct system. Each patient had a one-time or multiple hospitalization at the Nephrology Department of the Pediatric Clinic, with performed: ultrasound which confirmed CH, voiding cystourethrography / voiding urosonography was confirmed based on which the vesicoureteral reflux (VUR) was established / excluded, dynamic renal scintigraphy and magnetic urography (analysis was made by CHOP-fMRU software) on the basis of which the uterine anatomy and the relative renal function were evaluated. Results: Male patients were represented in 40 cases (69%). The average age was 4.4 ± 4.3 years with the youngest patient at the age of 2 months, and the oldest was 17 years old. According to diagnostic entities, the most common diagnosis was ureteropelvic junction (UPJ) obstruction in over half of cases (30 or 51.7%), followed by subjects with ureterovesical junction (UVJ) obstruction (11 or 19%), VUR was recorded in 9 (15.5%) cases, and pyelon fissus in 7 (12.1%), and one case (1.7%) was recorded with bilateral megaureter. Comparison of the value of the renal function obtained with DRS and CHOP-fMRU methods shows that there were no statistically significant differences between two methods. In the case of right kidney, the mean DRS value was 53.4 ± 18.4% (range 13-100%), while CHOP-fMRU was 51.8 ± 22.4 (range 0-96.7%). In the case of left kidney, the average value according to the DRS method was 46.9 ± 18.9% (range 0-87%) and according to CHOP-fMRU 47.6 ± 21.5% (range 8.3-100%). The correlation coefficients of both right and left kidneys show a highly statistically significant correlation between these two methods. Conclusion: Magnetic resonance urography in the pediatric population in CH based on results should be an integral part of the management of these patients, especially in congenital obstructive uropathy, in complex and associated congenital anomalies, as it provides morphological and functional data on the state of the kidneys and urinary tract.
{"title":"Evaluation of Congenital Hydronephrosis with Static and Dynamic Magnetic Resonance Urography in Comparation to Dynamic Renal Scintigraphy","authors":"Amra Džananović, A. Begić, D. Pokrajac","doi":"10.5455/aim.2019.27.181-185","DOIUrl":"https://doi.org/10.5455/aim.2019.27.181-185","url":null,"abstract":"Introduction: Congenital hydronephrosis (CH) is a condition with dilated renal pelvis with or without dilation of renal calyces. Aim: To examine the role of magnetic resonance urography in the detection of congenital hydronephrosis in comparison to dynamic renal scintigraphy (DRS). Patients and methods: Resarch included 58 (n=58) patients with diagnosis of congenital unilateral or bilateral dilatation of kidney duct system. Each patient had a one-time or multiple hospitalization at the Nephrology Department of the Pediatric Clinic, with performed: ultrasound which confirmed CH, voiding cystourethrography / voiding urosonography was confirmed based on which the vesicoureteral reflux (VUR) was established / excluded, dynamic renal scintigraphy and magnetic urography (analysis was made by CHOP-fMRU software) on the basis of which the uterine anatomy and the relative renal function were evaluated. Results: Male patients were represented in 40 cases (69%). The average age was 4.4 ± 4.3 years with the youngest patient at the age of 2 months, and the oldest was 17 years old. According to diagnostic entities, the most common diagnosis was ureteropelvic junction (UPJ) obstruction in over half of cases (30 or 51.7%), followed by subjects with ureterovesical junction (UVJ) obstruction (11 or 19%), VUR was recorded in 9 (15.5%) cases, and pyelon fissus in 7 (12.1%), and one case (1.7%) was recorded with bilateral megaureter. Comparison of the value of the renal function obtained with DRS and CHOP-fMRU methods shows that there were no statistically significant differences between two methods. In the case of right kidney, the mean DRS value was 53.4 ± 18.4% (range 13-100%), while CHOP-fMRU was 51.8 ± 22.4 (range 0-96.7%). In the case of left kidney, the average value according to the DRS method was 46.9 ± 18.9% (range 0-87%) and according to CHOP-fMRU 47.6 ± 21.5% (range 8.3-100%). The correlation coefficients of both right and left kidneys show a highly statistically significant correlation between these two methods. Conclusion: Magnetic resonance urography in the pediatric population in CH based on results should be an integral part of the management of these patients, especially in congenital obstructive uropathy, in complex and associated congenital anomalies, as it provides morphological and functional data on the state of the kidneys and urinary tract.","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"27 1","pages":"181 - 185"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44443724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-01DOI: 10.5455/aim.2019.27.192-198
Fahad Kamal Alsheref
Introduction: The number of social network users is on the rise, and the size of the user-generated contents is increasing as well. Analyzing the generated contents can lead to the attainment of a vast amount of information, such as users’ feelings on specific products or events, or personal information about life events. Aim: The aim of this paper is to describe an model for detecting medical information present in generated contents, such as posts or comments. Results: The proposed model is based on the Unified Medical Language System (UMLS) and is tested on a dataset collected from Twitter and Facebook. The extracted information can be used to aid in the early detection of diseases or to supply commercial benefits to medical companies. Experimental results demonstrate that the proposed model achieves 94.6% accuracy and 87% precision. Conclusion: In this study, we attempted to extract clinical information present in UGC. Using the proposed model should involve a reliable dataset that contains most clinical expressions; the UMLS was a suitable dataset for our model.
{"title":"Medical Information Extraction Model for User-generated Content","authors":"Fahad Kamal Alsheref","doi":"10.5455/aim.2019.27.192-198","DOIUrl":"https://doi.org/10.5455/aim.2019.27.192-198","url":null,"abstract":"Introduction: The number of social network users is on the rise, and the size of the user-generated contents is increasing as well. Analyzing the generated contents can lead to the attainment of a vast amount of information, such as users’ feelings on specific products or events, or personal information about life events. Aim: The aim of this paper is to describe an model for detecting medical information present in generated contents, such as posts or comments. Results: The proposed model is based on the Unified Medical Language System (UMLS) and is tested on a dataset collected from Twitter and Facebook. The extracted information can be used to aid in the early detection of diseases or to supply commercial benefits to medical companies. Experimental results demonstrate that the proposed model achieves 94.6% accuracy and 87% precision. Conclusion: In this study, we attempted to extract clinical information present in UGC. Using the proposed model should involve a reliable dataset that contains most clinical expressions; the UMLS was a suitable dataset for our model.","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"27 1","pages":"192 - 198"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42614580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-01DOI: 10.5455/aim.2019.27.152-157
Dewi Ratih Tirto Sari, J. Cairns, A. Safitri, F. Fatchiyah
Introduction: Anthocyanin is the bioactive compound in black rice, which promotes some health benefits for human body. Present study revealed that black rice anthocyanins improve the biomarker of the metabolic syndrome, such as tumor necrosis factor alpha (TNF-α). However, the mechanism of anthocyanin in preventing metabolic syndrome has not been elucidated. Aim: This study was performed to identify the interaction of six types of black rice anthocyanin towards TNF-α protein and TNF-α receptor through in silico studies, to assess the molecular properties and bioactivity of black rice anthocyanin. Methods: We retrieved the black rice anthocyanin compounds from the PubChem database and the proteins (TNF-α protein and TNF-α receptor) from Protein Data Bank (PDB) database. Protein and ligands were docked using Hex 8.0 software and visualized by Discovery Studio 4.1 program. Results: This study found the possibility that black rice anthocyanins interacted with TNF-α have no influence into TNF-α and TNF-α receptor interaction. The binding of delphinidin-3-O-glucoside & peonidin-3-O-glucoside to TNF-α receptor inhibited the TNF-α and TNF-α receptor signaling. The black rice anthocyanins had low activity as a drug. Interestingly, black rice anthocyanins had a potency as an antioxidant due to the hydrogen donor or acceptor in their structure, as protein kinase inhibitor, nuclear receptor ligand, and enzyme kinase inhibitor. Conclusion: This study suggests that delphinidin-3-O-glucoside and peonidin-3-O-glucoside might have function as anti-inflammatory factor related with TNF-α signaling.
简介:花青素是黑米中的生物活性化合物，对人体有一定的健康益处。目前的研究表明，黑米花青素可以改善代谢综合征的生物标志物，如肿瘤坏死因子α (TNF-α)。然而，花青素预防代谢综合征的机制尚未阐明。目的:通过硅片研究，鉴定黑米花青素6种类型与TNF-α蛋白和TNF-α受体的相互作用，评价黑米花青素的分子特性和生物活性。方法:从PubChem数据库中检索黑米花青素化合物，从protein Data Bank (PDB)数据库中检索蛋白质(TNF-α蛋白和TNF-α受体)。用Hex 8.0软件对接蛋白和配体，用Discovery Studio 4.1程序可视化。结果:本研究发现黑米花青素与TNF-α相互作用的可能性不影响TNF-α与TNF-α受体的相互作用。飞燕草苷-3- o -葡萄糖苷和芍药苷-3- o -葡萄糖苷与TNF-α受体的结合抑制了TNF-α和TNF-α受体的信号传导。黑米花青素作为药物的活性较低。有趣的是，黑米花青素由于其结构中的氢供体或受体，作为蛋白激酶抑制剂，核受体配体和酶激酶抑制剂具有抗氧化剂的效力。结论:本研究提示飞燕草苷-3- o -葡萄糖苷和芍药苷-3- o -葡萄糖苷可能具有与TNF-α信号通路相关的抗炎因子作用。
{"title":"Virtual Prediction of the Delphinidin-3-O-glucoside and Peonidin-3-O-glucoside as Anti-inflammatory of TNF-α Signaling","authors":"Dewi Ratih Tirto Sari, J. Cairns, A. Safitri, F. Fatchiyah","doi":"10.5455/aim.2019.27.152-157","DOIUrl":"https://doi.org/10.5455/aim.2019.27.152-157","url":null,"abstract":"Introduction: Anthocyanin is the bioactive compound in black rice, which promotes some health benefits for human body. Present study revealed that black rice anthocyanins improve the biomarker of the metabolic syndrome, such as tumor necrosis factor alpha (TNF-α). However, the mechanism of anthocyanin in preventing metabolic syndrome has not been elucidated. Aim: This study was performed to identify the interaction of six types of black rice anthocyanin towards TNF-α protein and TNF-α receptor through in silico studies, to assess the molecular properties and bioactivity of black rice anthocyanin. Methods: We retrieved the black rice anthocyanin compounds from the PubChem database and the proteins (TNF-α protein and TNF-α receptor) from Protein Data Bank (PDB) database. Protein and ligands were docked using Hex 8.0 software and visualized by Discovery Studio 4.1 program. Results: This study found the possibility that black rice anthocyanins interacted with TNF-α have no influence into TNF-α and TNF-α receptor interaction. The binding of delphinidin-3-O-glucoside & peonidin-3-O-glucoside to TNF-α receptor inhibited the TNF-α and TNF-α receptor signaling. The black rice anthocyanins had low activity as a drug. Interestingly, black rice anthocyanins had a potency as an antioxidant due to the hydrogen donor or acceptor in their structure, as protein kinase inhibitor, nuclear receptor ligand, and enzyme kinase inhibitor. Conclusion: This study suggests that delphinidin-3-O-glucoside and peonidin-3-O-glucoside might have function as anti-inflammatory factor related with TNF-α signaling.","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"27 1","pages":"152 - 157"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42768421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-01DOI: 10.5455/aim.2019.27.167-170
S. Toghyani, I. Nasseh, G. Aoun, M. Noujeim
Introduction: Fractal dimension (FD) on periapical radiographs is used as a simple descriptor of the complex architecture of the trabecular bone surrounding the dentition. It is used on periapical and panoramic radiographs as a descriptor of the complex architecture of trabecular bone surrounding teeth. Aim: The aim of this study was to evaluate the effect of image resolution and different compression levels on fractal dimension of alveolar bone with images obtained using storage phosphor plate (SPP) system. Methods: Periapical images of premolar and molar teeth on both sides of three dry human mandibles were obtained with Digora Optime (Soredex Corp., Helsinki, Finland) SPP system. The SPPs were exposed equally and scanned immediately after exposure with standard, high and very high resolutions. All the images then were compressed and saved by degrees of 0%, 25%, 50%, 75% and 90%. FD was calculated using public domain software (ImageJ with FracLac plug-in) on two non-overlapping regions of interest (ROIs) on premolar and molar periapical bone areas of each radiograph using differential box-counting method. The ROIs on corresponding images were of the same size and position. FDs were compared using two-way ANOVA and Tukey–Kramer multiple comparison tests (p=0.05). Results: There was no significant difference in FD calculations in different levels of compression for all the resolutions. Images obtained with high resolution scans showed significantly lower variation in FD values compared to very high and standard resolutions for all compressions (p<0.0001). Conclusion: The high resolution demonstrated the lowest variation in FD values in all levels of compression which makes it the most reliable and consistent resolution for measuring the FD values. The level of compression does not make a significant difference in FD values for all the scan resolutions. Scanning resolution of SPPs should be carefully chosen when evaluating the change in FD of alveolar bone for various bone disorders.
根尖周x线片上的分形维数(FD)是牙列周围小梁骨复杂结构的简单描述符。它用于根尖周和全景x线片，作为描述牙齿周围小梁骨复杂结构的描述符。目的:利用存储磷光板(SPP)系统获得的图像，评价图像分辨率和不同压缩水平对牙槽骨分形维数的影响。方法:采用Digora Optime (Soredex Corp.， Helsinki, Finland) SPP系统对3例干性下颌骨的前磨牙和双侧磨牙进行根尖周成像。spp均匀暴露，暴露后立即进行标准、高、超高分辨率扫描。然后将所有图像按0%、25%、50%、75%和90%的程度进行压缩和保存。使用公共领域软件(ImageJ with FracLac插件)对每张x线片上前磨牙和磨牙根尖周骨区域的两个非重叠感兴趣区域(roi)采用微分盒计数法计算FD。对应图像上的roi大小和位置相同。fd的比较采用双因素方差分析和Tukey-Kramer多重比较检验(p=0.05)。结果:在不同压缩水平下，所有分辨率的FD计算结果无显著差异。与所有压缩的非常高分辨率和标准分辨率相比，高分辨率扫描获得的图像显示FD值的变化显著降低(p<0.0001)。结论:高分辨率在所有压缩水平下FD值的变化最小，是测量FD值最可靠和一致的分辨率。压缩级别对所有扫描分辨率的FD值没有显著影响。在评价各种骨疾病的牙槽骨FD变化时，应慎重选择spp的扫描分辨率。
{"title":"Effect of Image Resolution and Compression on Fractal Analysis of the Periapical Bone","authors":"S. Toghyani, I. Nasseh, G. Aoun, M. Noujeim","doi":"10.5455/aim.2019.27.167-170","DOIUrl":"https://doi.org/10.5455/aim.2019.27.167-170","url":null,"abstract":"Introduction: Fractal dimension (FD) on periapical radiographs is used as a simple descriptor of the complex architecture of the trabecular bone surrounding the dentition. It is used on periapical and panoramic radiographs as a descriptor of the complex architecture of trabecular bone surrounding teeth. Aim: The aim of this study was to evaluate the effect of image resolution and different compression levels on fractal dimension of alveolar bone with images obtained using storage phosphor plate (SPP) system. Methods: Periapical images of premolar and molar teeth on both sides of three dry human mandibles were obtained with Digora Optime (Soredex Corp., Helsinki, Finland) SPP system. The SPPs were exposed equally and scanned immediately after exposure with standard, high and very high resolutions. All the images then were compressed and saved by degrees of 0%, 25%, 50%, 75% and 90%. FD was calculated using public domain software (ImageJ with FracLac plug-in) on two non-overlapping regions of interest (ROIs) on premolar and molar periapical bone areas of each radiograph using differential box-counting method. The ROIs on corresponding images were of the same size and position. FDs were compared using two-way ANOVA and Tukey–Kramer multiple comparison tests (p=0.05). Results: There was no significant difference in FD calculations in different levels of compression for all the resolutions. Images obtained with high resolution scans showed significantly lower variation in FD values compared to very high and standard resolutions for all compressions (p<0.0001). Conclusion: The high resolution demonstrated the lowest variation in FD values in all levels of compression which makes it the most reliable and consistent resolution for measuring the FD values. The level of compression does not make a significant difference in FD values for all the scan resolutions. Scanning resolution of SPPs should be carefully chosen when evaluating the change in FD of alveolar bone for various bone disorders.","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"27 1","pages":"167 - 170"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45316535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-01DOI: 10.5455/aim.2019.27.171-176
S. Bashir, Raidah Baradi, F. Al-Ghamdi
Introduction: Voxel-based morphometry (VBM) is a neuroimaging analysis technique that allows investigation of focal differences in brain anatomy, using the statistical approach of statistical parametric mapping. Gender changes are probably expressed in the human brain in the form of functional and anatomical organization. Aim: Our aim was to study gender differences and anatomical abnormalities in epilepsy patients (EP) by voxel-based morphometry (VBM) methods. Methods: Cortical thickness analysis of whole brain was performed in 28 patients with EP and 30 controls for gender and hemispheric differences. Results: Cortical thickness abnormalities were more widespread in left side of the brain in EP; while in female changes were mostly seen in temporal areas, frontal regions were more affected in male. Conclusion: Our study confirmed that gender and laterality are important factors determining the brain damage in EP.
{"title":"Gender and Hemispheric Differences in Epilepsy Diagnosed by Voxel-based Morphometry (VBM) Method: a Pilot Cortical Thickness Study","authors":"S. Bashir, Raidah Baradi, F. Al-Ghamdi","doi":"10.5455/aim.2019.27.171-176","DOIUrl":"https://doi.org/10.5455/aim.2019.27.171-176","url":null,"abstract":"Introduction: Voxel-based morphometry (VBM) is a neuroimaging analysis technique that allows investigation of focal differences in brain anatomy, using the statistical approach of statistical parametric mapping. Gender changes are probably expressed in the human brain in the form of functional and anatomical organization. Aim: Our aim was to study gender differences and anatomical abnormalities in epilepsy patients (EP) by voxel-based morphometry (VBM) methods. Methods: Cortical thickness analysis of whole brain was performed in 28 patients with EP and 30 controls for gender and hemispheric differences. Results: Cortical thickness abnormalities were more widespread in left side of the brain in EP; while in female changes were mostly seen in temporal areas, frontal regions were more affected in male. Conclusion: Our study confirmed that gender and laterality are important factors determining the brain damage in EP.","PeriodicalId":7074,"journal":{"name":"Acta Informatica Medica","volume":"27 1","pages":"171 - 176"},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48509655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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