Pub Date : 1970-12-01DOI: 10.3109/rhe1.1970.16.issue-1-4.09
S. Ericson, E. Sundmark
SummarySecretion from the parotid and the lacrimal glands has been studied in two similar groups of 48 subjects, one consisting of RA patients, the other a control group. Sialometry and sialography has been performed as regards the parotid glands; the secretion of the lacrimal glands has been measured with Schirmer's test I and the occurrence of conjunctival and corneal epithelial defects stainable with Rose-Bengal has been studied.It has been shown that lacrimal and parotid secretion was significantly reduced in the RA group as compared with the control group; that epithelial defects typical for KCS occurred significantly more often in the RA group; that parenchymal changes, sialodochiectasias, existed in the RA group but that sialodochiectasias were completely absent in the control group; that there was no significant co-variation in the RA group between lacrimal and salivary secretion or lacrimal secretion and sialodochiectasias; that criteria for Sjogren's syndrome were fulfilled by 15 subjects in the...
{"title":"Studies on the sicca syndrome in patients with rheumatoid arthritis.","authors":"S. Ericson, E. Sundmark","doi":"10.3109/rhe1.1970.16.issue-1-4.09","DOIUrl":"https://doi.org/10.3109/rhe1.1970.16.issue-1-4.09","url":null,"abstract":"SummarySecretion from the parotid and the lacrimal glands has been studied in two similar groups of 48 subjects, one consisting of RA patients, the other a control group. Sialometry and sialography has been performed as regards the parotid glands; the secretion of the lacrimal glands has been measured with Schirmer's test I and the occurrence of conjunctival and corneal epithelial defects stainable with Rose-Bengal has been studied.It has been shown that lacrimal and parotid secretion was significantly reduced in the RA group as compared with the control group; that epithelial defects typical for KCS occurred significantly more often in the RA group; that parenchymal changes, sialodochiectasias, existed in the RA group but that sialodochiectasias were completely absent in the control group; that there was no significant co-variation in the RA group between lacrimal and salivary secretion or lacrimal secretion and sialodochiectasias; that criteria for Sjogren's syndrome were fulfilled by 15 subjects in the...","PeriodicalId":7146,"journal":{"name":"Acta rheumatologica Scandinavica","volume":"39 1","pages":"60-80"},"PeriodicalIF":0.0,"publicationDate":"1970-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78173057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1970-12-01DOI: 10.3109/rhe1.1970.16.issue-1-4.07
H. Laitinen, S. Saksanen, H. Suoranta
SummaryChanges in the manubrio-sternal articulation (MSA) were examined radiologically in 87 patients with rheumatoid arthritis and in a control group comprised of 23 patients with osteoarthritis and 72 subjects without joint disease. Erosions, reactive sclerosis and ankylosis were encountered in 70 % of the rheumatoid arthritis group and in 27 % of controls. There was no difference in the incidence of changes in persons with osteoarthritis and in the other control subjects.
{"title":"Involvement of the manubrio-sternal articulation in rheumatoid arthritis.","authors":"H. Laitinen, S. Saksanen, H. Suoranta","doi":"10.3109/rhe1.1970.16.issue-1-4.07","DOIUrl":"https://doi.org/10.3109/rhe1.1970.16.issue-1-4.07","url":null,"abstract":"SummaryChanges in the manubrio-sternal articulation (MSA) were examined radiologically in 87 patients with rheumatoid arthritis and in a control group comprised of 23 patients with osteoarthritis and 72 subjects without joint disease. Erosions, reactive sclerosis and ankylosis were encountered in 70 % of the rheumatoid arthritis group and in 27 % of controls. There was no difference in the incidence of changes in persons with osteoarthritis and in the other control subjects.","PeriodicalId":7146,"journal":{"name":"Acta rheumatologica Scandinavica","volume":"54 1","pages":"40-6"},"PeriodicalIF":0.0,"publicationDate":"1970-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84723438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1970-12-01DOI: 10.3109/rhe1.1970.16.issue-1-4.30
E. Kass
The importance of orthopedic surgery as an auxiliary to any treatment of rheumatoid arthritis is underlined in the present article. No treatment programme for rheumatoid arthritis is satisfactory, if it does not recognize this fact. It must form part of all future planning for hospital care of rheumatological patients.
{"title":"Collaboration between rheumatologist and orthopedic surgeon--a necessity.","authors":"E. Kass","doi":"10.3109/rhe1.1970.16.issue-1-4.30","DOIUrl":"https://doi.org/10.3109/rhe1.1970.16.issue-1-4.30","url":null,"abstract":"The importance of orthopedic surgery as an auxiliary to any treatment of rheumatoid arthritis is underlined in the present article. No treatment programme for rheumatoid arthritis is satisfactory, if it does not recognize this fact. It must form part of all future planning for hospital care of rheumatological patients.","PeriodicalId":7146,"journal":{"name":"Acta rheumatologica Scandinavica","volume":"1 1","pages":"257-60"},"PeriodicalIF":0.0,"publicationDate":"1970-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89492296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1970-12-01DOI: 10.3109/rhe1.1970.16.issue-1-4.16
E. Sairanen, A. Itkonen, S. Kangas
SummaryA case of PXE is reported which, besides cardiac and gastrointestinal symptoms, also shows recurrent joint manifestations, possibly due to the basic disease. Histologically, the joint lesions resembled subacute synovitis to some extent.
{"title":"Pseudoxanthoma elasticum (pxe) and joint manifestations.","authors":"E. Sairanen, A. Itkonen, S. Kangas","doi":"10.3109/rhe1.1970.16.issue-1-4.16","DOIUrl":"https://doi.org/10.3109/rhe1.1970.16.issue-1-4.16","url":null,"abstract":"SummaryA case of PXE is reported which, besides cardiac and gastrointestinal symptoms, also shows recurrent joint manifestations, possibly due to the basic disease. Histologically, the joint lesions resembled subacute synovitis to some extent.","PeriodicalId":7146,"journal":{"name":"Acta rheumatologica Scandinavica","volume":"17 1","pages":"130-5"},"PeriodicalIF":0.0,"publicationDate":"1970-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73638554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1970-12-01DOI: 10.3109/rhe1.1970.16.issue-1-4.05
H. Julkunen, Pentti Rokkanen
SummaryThe aim of the study was to elucidate histological changes provoked by Mycobacterium butyricum toxine in the rat joints, stomach, small intestine and thymus and the uptake of tritiated thymidine. Freund's complete adjuvant was injected into the base of the vastus muscle of 35 rats; 21 rats served as controls. Fifteen rats displayed histologically mild synovitis in the ankle joint, two periostitis and three muscle infiltrates. Histological study revealed no difference between the test animals and the controls in the stomach, small intestine and thymus. The thymidine uptake of the adjacent growth lines of the knee, stomach mucosa, small intestine, spleen and liver was the same in both groups. In contrast, the uptake of the cells of the thymus was smaller in the adjuvant-treated rats with a probability of over 90 per cent. This suggests that the mitosis of adjuvant-induced thymic cells is smaller than in cells with a normal condition.
{"title":"Arthritis induced with Freund's adjuvant and its relationship to changes in the stomach, small intestine and thymus. A histological and tritiated thymidine study on rats.","authors":"H. Julkunen, Pentti Rokkanen","doi":"10.3109/rhe1.1970.16.issue-1-4.05","DOIUrl":"https://doi.org/10.3109/rhe1.1970.16.issue-1-4.05","url":null,"abstract":"SummaryThe aim of the study was to elucidate histological changes provoked by Mycobacterium butyricum toxine in the rat joints, stomach, small intestine and thymus and the uptake of tritiated thymidine. Freund's complete adjuvant was injected into the base of the vastus muscle of 35 rats; 21 rats served as controls. Fifteen rats displayed histologically mild synovitis in the ankle joint, two periostitis and three muscle infiltrates. Histological study revealed no difference between the test animals and the controls in the stomach, small intestine and thymus. The thymidine uptake of the adjacent growth lines of the knee, stomach mucosa, small intestine, spleen and liver was the same in both groups. In contrast, the uptake of the cells of the thymus was smaller in the adjuvant-treated rats with a probability of over 90 per cent. This suggests that the mitosis of adjuvant-induced thymic cells is smaller than in cells with a normal condition.","PeriodicalId":7146,"journal":{"name":"Acta rheumatologica Scandinavica","volume":"35 1","pages":"22-9"},"PeriodicalIF":0.0,"publicationDate":"1970-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82522955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1970-12-01DOI: 10.3109/rhe1.1970.16.issue-1-4.19
R. Stenström, O. Wegelius
Summary125I-labelled Urographin has been used intra-articularly as tracer and 60 per cent Urographin as contrast in ten knee joints of patients with classical rheumatoid arthritis. Nine traumatic knees served as controls. The rapid rate of disappearance of the contrast from joints with rheumatoid inflammation was higher than in controls. Over the rheumatoid joints the radioactivity had decreased to half the initial value in 2.85 hrs. and over the traumatic joints in 3.70 hrs. In the radiographs clear evidence of absorption of contrast by the synovial membrane, the hyaline cartilage and the fibrocartilaginous tissue of the menisci was demonstrated.In one case visual proof was obtained of drainage of the contrast through the local lymphatics. The series of arthrograms taken from this knee indicate that this drainage was rapid.
{"title":"Clearance of 125I-labelled urographin from knee joints in rheumatoid arthritis.","authors":"R. Stenström, O. Wegelius","doi":"10.3109/rhe1.1970.16.issue-1-4.19","DOIUrl":"https://doi.org/10.3109/rhe1.1970.16.issue-1-4.19","url":null,"abstract":"Summary125I-labelled Urographin has been used intra-articularly as tracer and 60 per cent Urographin as contrast in ten knee joints of patients with classical rheumatoid arthritis. Nine traumatic knees served as controls. The rapid rate of disappearance of the contrast from joints with rheumatoid inflammation was higher than in controls. Over the rheumatoid joints the radioactivity had decreased to half the initial value in 2.85 hrs. and over the traumatic joints in 3.70 hrs. In the radiographs clear evidence of absorption of contrast by the synovial membrane, the hyaline cartilage and the fibrocartilaginous tissue of the menisci was demonstrated.In one case visual proof was obtained of drainage of the contrast through the local lymphatics. The series of arthrograms taken from this knee indicate that this drainage was rapid.","PeriodicalId":7146,"journal":{"name":"Acta rheumatologica Scandinavica","volume":"1 1","pages":"151-60"},"PeriodicalIF":0.0,"publicationDate":"1970-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90057162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1970-12-01DOI: 10.3109/rhe1.1970.16.issue-1-4.26
G. Lörincz, H. Isomäki, J. Martio
Summary27 rheumatic patients with knee joint hydrops were studied for the effect of osmic acid on the synovial fluid. Special interest was taken in synovial leucocyte counts and electrophoretic patterns. A leucopenia preceded the leucocytosis in the synovial samples; both were thought to be induced by osmium. A precipitate formation from hyaluronate was thought to account for the leucopenia and this suggests a new hypothesis of osmic acid action. In the electrophoretic patterns there was a change in the electric charges of proteins. One week after osmic acid injection the pattern was normal.
{"title":"Changes in the synovial fluid caused by osmic acid.","authors":"G. Lörincz, H. Isomäki, J. Martio","doi":"10.3109/rhe1.1970.16.issue-1-4.26","DOIUrl":"https://doi.org/10.3109/rhe1.1970.16.issue-1-4.26","url":null,"abstract":"Summary27 rheumatic patients with knee joint hydrops were studied for the effect of osmic acid on the synovial fluid. Special interest was taken in synovial leucocyte counts and electrophoretic patterns. A leucopenia preceded the leucocytosis in the synovial samples; both were thought to be induced by osmium. A precipitate formation from hyaluronate was thought to account for the leucopenia and this suggests a new hypothesis of osmic acid action. In the electrophoretic patterns there was a change in the electric charges of proteins. One week after osmic acid injection the pattern was normal.","PeriodicalId":7146,"journal":{"name":"Acta rheumatologica Scandinavica","volume":"16 1","pages":"217-22"},"PeriodicalIF":0.0,"publicationDate":"1970-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87684254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1970-12-01DOI: 10.3109/rhe1.1970.16.issue-1-4.28
H. Asai, R. Nakamura
SummaryPSP clearance of the osteoarthritic knee was studied in 79 joints of 60 patients. Correlation between the clearance rate and the degree of disease activity (the grade of inflammatory exacerbation) was suggestive.Using PSP clearance, we studied the effect of non-steroidal anti-inflammatory drugs on the osteoarthritic knee. The results of this study are as follows: The drugs, phenylbutazone, indomethacin and acetylsalicylic acid, are effective, when they are administered at the initial phase of inflammation, while in the chronic phase the effects of them are variable, though significant in patients whose PSP clearance rate is below 45 per cent. In the chronic and severely affected cases, the basic principles of therapy of osteoarthritic knees are avoidance of excessive use and the correct use of rest and physical therapy.
{"title":"Effect of non-steroidal anti-inflammatory drugs on osteoarthritis of the knee. With special reference to PSP clearance as an indicator.","authors":"H. Asai, R. Nakamura","doi":"10.3109/rhe1.1970.16.issue-1-4.28","DOIUrl":"https://doi.org/10.3109/rhe1.1970.16.issue-1-4.28","url":null,"abstract":"SummaryPSP clearance of the osteoarthritic knee was studied in 79 joints of 60 patients. Correlation between the clearance rate and the degree of disease activity (the grade of inflammatory exacerbation) was suggestive.Using PSP clearance, we studied the effect of non-steroidal anti-inflammatory drugs on the osteoarthritic knee. The results of this study are as follows: The drugs, phenylbutazone, indomethacin and acetylsalicylic acid, are effective, when they are administered at the initial phase of inflammation, while in the chronic phase the effects of them are variable, though significant in patients whose PSP clearance rate is below 45 per cent. In the chronic and severely affected cases, the basic principles of therapy of osteoarthritic knees are avoidance of excessive use and the correct use of rest and physical therapy.","PeriodicalId":7146,"journal":{"name":"Acta rheumatologica Scandinavica","volume":"12 1","pages":"231-9"},"PeriodicalIF":0.0,"publicationDate":"1970-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72800588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1970-12-01DOI: 10.3109/03009747009165355
M. Kormano
The manubrio-sternal joints (MSJs) of 10 male and 10 female non-rheumatoid subjects and of 11 subjects with RA were studied. Microradiography often revealed herniation of the intra-articular fibrocartilaginous disc into the cancellous bone and osteo-arthritic changes. In RA, erosive destruction of the articular surfaces was seen in six cases and in one subject the joint was ankylotic. Histologically the MSJ presented degenerative phenomena but no inflammatory changes in old non-rheumatic subjects. Active inflammation was visible in four joints from rheumatoid subjects, and in another four fibrous replacement suggestive of earlier inflammation was seen. The joints from non-rheumatoid subjects presented a histological joint cavity in nine cases, with or without synovial-like cells lining the cavity. A similar cavity was present in only one of the joints taken from rheumatoid subjects and there were inflammatory changes in the synovial tissue in this joint. It is suggested that involvement of the MSJ in RA m...
{"title":"A microradiographic and histological study of the manubrio-sternal joint in rheumatoid arthritis.","authors":"M. Kormano","doi":"10.3109/03009747009165355","DOIUrl":"https://doi.org/10.3109/03009747009165355","url":null,"abstract":"The manubrio-sternal joints (MSJs) of 10 male and 10 female non-rheumatoid subjects and of 11 subjects with RA were studied. Microradiography often revealed herniation of the intra-articular fibrocartilaginous disc into the cancellous bone and osteo-arthritic changes. In RA, erosive destruction of the articular surfaces was seen in six cases and in one subject the joint was ankylotic. Histologically the MSJ presented degenerative phenomena but no inflammatory changes in old non-rheumatic subjects. Active inflammation was visible in four joints from rheumatoid subjects, and in another four fibrous replacement suggestive of earlier inflammation was seen. The joints from non-rheumatoid subjects presented a histological joint cavity in nine cases, with or without synovial-like cells lining the cavity. A similar cavity was present in only one of the joints taken from rheumatoid subjects and there were inflammatory changes in the synovial tissue in this joint. It is suggested that involvement of the MSJ in RA m...","PeriodicalId":7146,"journal":{"name":"Acta rheumatologica Scandinavica","volume":"1 1","pages":"47-59"},"PeriodicalIF":0.0,"publicationDate":"1970-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76348096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1970-12-01DOI: 10.3109/rhe1.1970.16.issue-1-4.17
E. Sairanen
SummaryOne case of congenital micrognathia unaccompanied by any other congenital malformations was discovered among 33,000 school children surveyed. This case showed roentgenological evidence of condylar aplasia. The same change had been noted earlier in some cases of juvenile rheumatoid arthritis associated with micrognathia. The conclusion is drawn that in some of the children with RA associated with micrognathia, this latter has a congenital basis whereas, in other cases, it is due to affection of the temporomandibular joint.
{"title":"On the etiology of growth disturbance of the mandible in juvenile rheumatoid arthritis.","authors":"E. Sairanen","doi":"10.3109/rhe1.1970.16.issue-1-4.17","DOIUrl":"https://doi.org/10.3109/rhe1.1970.16.issue-1-4.17","url":null,"abstract":"SummaryOne case of congenital micrognathia unaccompanied by any other congenital malformations was discovered among 33,000 school children surveyed. This case showed roentgenological evidence of condylar aplasia. The same change had been noted earlier in some cases of juvenile rheumatoid arthritis associated with micrognathia. The conclusion is drawn that in some of the children with RA associated with micrognathia, this latter has a congenital basis whereas, in other cases, it is due to affection of the temporomandibular joint.","PeriodicalId":7146,"journal":{"name":"Acta rheumatologica Scandinavica","volume":"54 1","pages":"136-43"},"PeriodicalIF":0.0,"publicationDate":"1970-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75096737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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