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Epidemiological profile of salivary gland lesions diagnosed in a higher education institution: an observational and retrospective study of 381 cases 高等院校涎腺病变的流行病学分析:381例的观察性和回顾性研究
Pub Date : 2020-04-22 DOI: 10.4025/actascihealthsci.v42i1.51032
Claudio Freire Sesenta Junior, Camila Camarini, I. Balan, L. Iwaki, M. C. Silva, E. S. Tolentino
The aim of this retrospective and observational study was to report the prevalence and characteristics of salivary gland lesions (SGL) in patients treated at the State University of Maringa, between 1995 and 2018. Data from medical records of patients with neoplastic and non-neoplastic SGL concerning to age, sex, ethnicity, anatomical location, microscopic diagnosis and treatment were collected. All SGL with diagnosis confirmed by microscopic examination were considered. Of the 3,127 biopsied lesions, 381 (12.1%) SGL were identified. Caucasian (71%) women (51%) aging from 11 to 20 years (33%) were more affected. 88.5% (n= 337) were non-neoplastic lesions, 7% (n= 27) benign neoplasms and 4.5% (n= 17) malignant neoplasms. Mucocele was the most prevalent lesion (n= 269%), followed by pleomorphic adenoma (n= 25%). Recognition and appropriate management of these lesions is essential, especially because malignant neoplastic lesions of the salivary glands can be very aggressive.
这项回顾性观察性研究的目的是报告1995年至2018年期间在马林加州立大学接受治疗的患者中唾液腺病变(SGL)的患病率和特征。从肿瘤和非肿瘤性SGL患者的医疗记录中收集有关年龄、性别、种族、解剖位置、显微镜诊断和治疗的数据。所有经显微镜检查确诊的SGL均被考虑。在3127例活检病灶中,381例(12.1%)SGL被发现。11 - 20岁的白种人(71%)、女性(51%)(33%)受影响更大。88.5% (n= 337)为非肿瘤性病变,7% (n= 27)为良性肿瘤,4.5% (n= 17)为恶性肿瘤。黏液囊肿是最常见的病变(269%),其次是多形性腺瘤(25%)。识别和适当的管理这些病变是必不可少的,特别是因为唾液腺的恶性肿瘤病变可以是非常积极的。
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引用次数: 1
Occurrence of respiratory symptoms in elderly persons heard by the family health strategy in Águas Lindas, Ananindeua, Pará State 帕尔<e:1>州Águas阿南迪努瓦州林达斯市家庭保健战略所了解的老年人呼吸道症状发生情况
Pub Date : 2020-04-22 DOI: 10.4025/actascihealthsci.v42i1.47682
R. C. Teixeira, Kézia Danniely da Silva Santos, M. Silva, V. M. F. Normando, Madacilina de Melo Teixeira
Respiratory diseases are among the five leading causes of death in Brazil, particularly among the elderly. This study identified the occurrence of respiratory symptoms in older persons. Specifically, a descriptive, observational, and quantitative study was conducted using a sample of elderly people enrolled in the Hypertension and Diabetes sessions of the Family Health Strategy program in a Brazilian city. MRC-ATS-DLD78 questionnaires were used to analyze respiratory symptoms with a sample comprised of 50 volunteers (mean age = 69.96 years). The median time living in a dwelling within a polluted sample area was 30 years, with 82% reporting spending more time per day at home or in the neighborhood. The presence of coughing was reported by 18% persons, expectoration (17%), productive cough (14%), wheezing (34%), dyspnea (12%), and respiratory diseases (26%). Physiological changes in aging associated with the effects of pollution exposure leave elderly people more vulnerable to respiratory diseases because they are predisposed to diseases, such as decreased pulmonary elasticity, elevated lung compliance, reduced oxygen diffusion capacity, reduced expiratory flow, and premature closure of airways. The occurrence of respiratory symptoms in the elderly was 30% with one symptom, two (22%), three (10%), four (6%), and five (2%).
呼吸系统疾病是巴西五大主要死亡原因之一,在老年人中尤其如此。这项研究确定了老年人呼吸道症状的发生。具体而言,对巴西某城市参加家庭健康战略项目高血压和糖尿病会议的老年人样本进行了描述性、观察性和定量研究。采用MRC-ATS-DLD78问卷对50名志愿者(平均年龄69.96岁)的呼吸道症状进行分析。在污染样本区内居住的时间中位数为30年,82%的人报告每天在家里或附近待的时间更长。18%的人报告有咳嗽、咳痰(17%)、生产性咳嗽(14%)、喘息(34%)、呼吸困难(12%)和呼吸系统疾病(26%)。与污染暴露影响相关的衰老生理变化使老年人更容易患呼吸系统疾病,因为他们易患诸如肺弹性下降、肺顺应性升高、氧气扩散能力降低、呼气流量减少和气道过早关闭等疾病。老年人呼吸道症状的发生率为30%,其中1种、2种(22%)、3种(10%)、4种(6%)、5种(2%)。
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引用次数: 0
Study of a delayed-release system for hard and soft capsules coated with eudragit® s100 acrylic polymers 涂覆eudragit®s100丙烯酸聚合物的软硬胶囊缓释系统的研究
Pub Date : 2020-03-10 DOI: 10.4025/actascihealthsci.v42i1.48422
L. A. Soares, E. Crema
The objective of this study was to evaluate a pH-dependent system of ileocolonic release of active ingredients using the polymer Eudragit® S100. A spouted bed was used in the coating process of soft capsules containing palm oil and of hard capsules containing glutamine under standardised experimental conditions. The height and diameter of the palm oil and glutamine capsules were measured using a calliper. The following variables were analysed: Eudragit® S100 dispersion amount used in the capsule coating process, nozzle air pressure, nozzle air flow rate, spray rate and temperature of the spouted bed coating process. The Eudragit® S100 dispersion formulation, trademarked as Quickstart® by Evonik Industries, was used with modifications to prepare the enteric coating. The results showed that the adequate temperature for the spouted bed coating process was 50°C and that 0.2 mL of 6.5% Eudragit® S100 coating per cm2 capsule was resistant for 60 minutes at pH 6.8. The findings demonstrate the pharmaceutical application of Eudragit® S100 in the modification of the coating and the preparation of a delayed-release system of hard and soft capsules, thus enabling ileal release of active ingredients.
本研究的目的是评估使用聚合物Eudragit®S100的回肠结肠活性成分释放的ph依赖系统。在标准化的实验条件下,采用喷淋床对棕榈油软胶囊和谷氨酰胺硬胶囊进行包衣。用卡尺测量棕榈油和谷氨酰胺胶囊的高度和直径。分析了以下变量:胶囊包衣过程中使用的Eudragit®S100分散量、喷嘴气压、喷嘴气流速率、喷淋床包衣过程的喷淋速率和温度。Eudragit®S100分散配方,由赢创工业公司注册为Quickstart®,经修改后用于制备肠溶涂层。结果表明,喷淋床涂层工艺的适宜温度为50℃,每cm2胶囊0.2 mL 6.5% Eudragit®S100涂层在pH 6.8下耐涂60分钟。研究结果证明了Eudragit®S100在修饰涂层和制备软硬胶囊缓释系统中的应用,从而实现了活性成分的回肠释放。
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引用次数: 2
Violation of children's and adolescents’ rights – the profile of a southern state in Brazil 侵犯儿童和青少年权利——巴西南部一个州的概况
Pub Date : 2020-03-10 DOI: 10.4025/actascihealthsci.v42i1.44453
Mariucha Ramella Marcon Nemer, Bruna de Souza Nogueira, Fernanda do Nascimento de Lemos Campos, Márcia Cristina da Silva, M. Alves, L. F. Lolli
The rights of children and adolescents are provided by law and it is the duty of the State, family and society to care for them. Health and education professionals are responsible for reporting suspected or confirmed cases of rights violation. This study aimed to investigate the prevalence and qualification of violation of children’s and adolescents’ rights in the State of Paraná between 2009 and 2014. A descriptive and observational quantitative study was carried out based on the records of the Child Protective Services in Paraná, accessed through the Information System for Childhood and Adolescence (SIPIA). A total of 129.123 violations of rights were found. Among those cases, the right to familiar and communitarian companionship stands out with the greatest number of violations, followed by the right to education, culture, sports and leisure. Mothers were found to be the main aggressors, followed by fathers, and sexual violence/abuse was the most prevalent type of violence. In conclusion, there was a significant amount of violation of children’s and adolescents’ rights in the State of Paraná during the period covered by this research, and it has increased over the years. Besides, we found out that there is a predisposition of gender and age group for each variable analyzed.
法律规定了儿童和青少年的权利,国家、家庭和社会有责任照顾他们。卫生和教育专业人员负责报告怀疑或确认的侵犯权利案件。本研究旨在调查2009年至2014年期间帕拉纳州侵犯儿童和青少年权利的发生率和资格。通过儿童和青少年信息系统(SIPIA)获取帕拉南儿童保护服务的记录,进行了一项描述性和观察性定量研究。共查获侵权案件129.123件。在这些案件中,亲密和社群陪伴的权利受到侵犯的次数最多,其次是受教育、文化、体育和休闲的权利。调查发现,母亲是主要的施暴者,其次是父亲,性暴力/虐待是最普遍的暴力类型。总而言之,在本研究所涉期间,在帕拉南州发生了大量侵犯儿童和青少年权利的事件,而且这些年来有所增加。此外,我们发现所分析的每个变量都有性别和年龄组的易感性。
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引用次数: 1
Decoding the aquatic motor behavior: description and reflection on the functional movement 水生运动行为的解码:对功能运动的描述与反思
Pub Date : 2020-02-27 DOI: 10.4025/actascihealthsci.v42i1.47129
D. D. Iucksch, Luize Bueno de Araújo, Karize Rafaela Mesquita Novakoski, B. Yamaguchi, C. F. Carneiro, Tainá Ribas Mélo, V. Israel
Aquatic environment is widely used for recreational, sporting, and therapeutic activities. However, human motor functional behavior in immersion has not been sufficiently described. Such description is necessary to improve strategies used to perform movements in this environment and to possibly transfer them to land. Our goal is to offer a qualitative description of the aquatic motor behavior. We use action research to observe and describe motor behavior in water, which we systematized using the Aquatic Functional Assessment Scale, effects of water on the immersed body, its relationship with functional movements performed on land, and the International Classification of Functioning, Disability and Health (ICF). The results allowed the systematization of aquatic movements based on unique features of water compared to effects of activities and participation of functional movement, under a biopsychosocial view of ICF. Such systematization of aquatic behaviors enables professionals to increase their strategies and interventions in water, through that understand the complexity of this approach and improve physical and therapeutic interventions that will have an impact on health.
水生环境被广泛用于娱乐、运动和治疗活动。然而,人类在沉浸状态下的运动功能行为还没有得到充分的描述。这种描述对于改进在这种环境中执行运动的策略以及可能将其转移到陆地上是必要的。我们的目标是提供水生运动行为的定性描述。我们使用行动研究来观察和描述水中的运动行为,我们使用水生功能评估量表,水对浸入体的影响,其与陆地上进行的功能运动的关系以及国际功能,残疾和健康分类(ICF)来系统化。在ICF的生物心理社会观点下,结果允许基于水的独特特征的水生运动的系统化,而不是活动的影响和功能性运动的参与。这种水生行为的系统化使专业人员能够增加他们在水中的策略和干预措施,从而了解这种方法的复杂性,并改进将对健康产生影响的物理和治疗干预措施。
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引用次数: 8
Molecular detection of oncogenic subtypes of human papillomavirus (HPV) in a group of women in the Amazon region of Brazil 巴西亚马逊地区一组妇女中人乳头瘤病毒(HPV)致癌亚型的分子检测
Pub Date : 2020-02-27 DOI: 10.4025/actascihealthsci.v42i1.50005
A. Silva, C. Bica, A. Vieira, C. Fantin
The natural history of cervical cancer is strongly related to the presence of human papillomavirus (HPV) infection, with its relationship with cervical cancer being a matter of concern. It is estimated that 70% of all cervical cancers worldwide are caused by HPV 16 and 18. Accordingly, the present study aimed to contribute to the identification of HPV subtypes circulating in a group of women of Manaus-Brazil. Cervical samples were collected from 49 women, following the eligibility criteria of the study, and DNA was then extracted from the samples, which were analyzed for the presence of the virus in the genetic material through the polymerase chain reaction (PCR) using generic primers (GP05/06). Finally, identification of the viral subtypes was performed using specific primers for the detection of the main subtypes already examined (16 and 18). Positive HPV DNA was detected in 100% of the samples included in the study. Human papillomavirus 16 was the most prevalent subtype in the majority of lesions, accounting for 29 (59.2%) of the positive cases, and HPV 18 was detected in four (8.2%) women. In these 4 cases there was co-infection, with the presence of both HPV 18 and HPV 16. Therefore, 40.8% (20 cases) in which HPV DNA was detected presented infection with other subtypes of HPV not included in the study. This data has clinical implications related to cervical cancer prevention, as the current prophylactic HPV vaccines are only effective against high-risk HPV 16 and 18 subtypes.
宫颈癌的自然史与人乳头瘤病毒(HPV)感染密切相关,其与宫颈癌的关系值得关注。据估计,全世界70%的宫颈癌是由HPV 16和18引起的。因此,本研究旨在帮助鉴定在巴西马瑙斯一组妇女中流传的HPV亚型。按照本研究的合格标准收集了49名妇女的宫颈样本,然后从样本中提取DNA,使用通用引物(GP05/06)通过聚合酶链反应(PCR)分析遗传物质中是否存在病毒。最后,使用特异性引物对已检测的主要亚型(16和18)进行病毒亚型鉴定。在研究中所有的样本中都检测到阳性HPV DNA。人乳头瘤病毒16型是大多数病变中最常见的亚型,占阳性病例的29例(59.2%),HPV 18型在4例(8.2%)女性中检测到。在这4例中,同时存在HPV 18和HPV 16感染。因此,40.8%(20例)检测到HPV DNA的患者存在未纳入研究的其他HPV亚型感染。这一数据具有与宫颈癌预防相关的临床意义,因为目前的预防性HPV疫苗仅对高危HPV 16和18亚型有效。
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引用次数: 1
Prevalence and factors associated to the use of illicit drugs and psychotropic medications among brazilian undergraduates 巴西大学生中使用非法药物和精神药物的流行情况及其相关因素
Pub Date : 2020-02-27 DOI: 10.4025/actascihealthsci.v42i1.46774
Merlyn dos Santos Maidana, C. F. L. Fernandes, S. Dumith, F. M. R. S. Silva Júnior
The aim of this study was to verify the prevalence of use of psychoactive substances (PS) and its associated factors in undergraduate students of a university in southern Brazil. The study was carried out with 830 undergraduate students in the year 2016. The individuals answered a self-administered questionnaire about the PS and its prevalence of daily use, in the last 30 days or at any time of their lives, as well as socioeconomic conditions and academic variables. Caffeine-based energy drinks was the most consumed psychoactive substance (96.3%) among undergraduates in the last 30 days, followed by alcohol (64.0%). Among the illicit drugs most consumed in the last 30 days was marijuana (17.3%), while anxiolytics and amphetamines were the most prevalent psychoactive medicaments in the last 30 days. The prevalence of lifetime illicit drugs used by these students was 41.5%, where we highlight besides marijuana (38.6%) the high consumption of cocaine (7.8%), ecstasy (9.3%) and solvents. Socioeconomic and demographic factors such as gender, have children, religion, and financial background as well as academic variables were associated to recent consumption of these substances. This study concluded there is a high prevalence of use of PS among the undergraduate students, including illicit drugs.
本研究的目的是验证精神活性物质(PS)在巴西南部一所大学本科生中的使用情况及其相关因素。这项研究是在2016年对830名本科生进行的。这些人回答了一份自我管理的问卷,内容涉及PS及其在过去30天或生命中任何时候的日常使用情况,以及社会经济条件和学术变量。在过去的30天里,含咖啡因的能量饮料是大学生消费最多的精神活性物质(96.3%),其次是酒精(64.0%)。在过去30天内吸食最多的非法药物是大麻(17.3%),而在过去30天内吸食最多的精神活性药物是抗焦虑药和安非他明。这些学生一生中使用违禁药物的比例为41.5%,其中除了大麻(38.6%)外,可卡因(7.8%)、摇头丸(9.3%)和溶剂的消费量也很高。社会经济和人口因素,如性别、是否有子女、宗教信仰、经济背景以及学术变量与近期这些物质的消费有关。本研究的结论是,大学生中PS的使用率很高,包括非法药物。
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引用次数: 6
Critical thinking skills for diagnosis process application from the perspective of nursing students and professors 从护生与教授的角度探讨批判性思维技能在诊断过程中的应用
Pub Date : 2020-02-01 DOI: 10.4025/actascihealthsci.v42i1.47681
Fernando Riegel, M. G. Crossetti
Identify, from the experiences of nursing students and their professors, the critical thinking skills necessary for applying the diagnosis process to clinical practice. Descriptive-exploratory with qualitative approach. The study was conducted at a higher education institution in the south of Brazil, after approval from the Research Ethics Committee, under CAEE No 72294917.7.0000.5347. It had the participation of five nursing students and four nursing professors through focal group sessions. The content analysis technique was used for data analysis. The most remarkable holistic critical thinking skills identified from the point of view of the nursing students were: analysis and knowledge; from the professors' perspective, they were: analysis, information search, clinical experience, knowledge transformation, contextual perspective, intuition, prediction and comprehension. With the findings of this research, professors will be capable of implementing strategies focused on the individual needs of students in order to qualify teaching practices as to the nursing diagnosis process.
从护理学生和他们的教授的经验中,确定将诊断过程应用于临床实践所必需的批判性思维技能。描述性-探索性与定性方法。该研究在巴西南部的一所高等教育机构进行,经研究伦理委员会批准,CAEE编号72294917.7.0000.5347。它通过焦点小组会议有五名护理学生和四名护理教授参与。数据分析采用内容分析技术。护生最显著的整体批判性思维能力为:分析与知识;从教授的角度来看,他们是:分析,信息搜索,临床经验,知识转化,情境视角,直觉,预测和理解。有了这项研究的结果,教授们将能够实施针对学生个人需求的策略,以便在护理诊断过程中合格的教学实践。
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引用次数: 0
Conceptions of women on cervical cancer screening 妇女对子宫颈癌普查的观念
Pub Date : 2018-11-30 DOI: 10.4025/ACTASCIHEALTHSCI.V40I1.35898
Camila Aparecida Pinheiro Landim Almeida, Gabriele Marques de Sousa, Renata Borges Monteiro, J. Muller, João Paulo Sampaio
Despite the high prevalence and incidence of cervical cancer, this disease can be avoided and has great healing potential when detected at early stages. Cervical cancer screening is used in monitoring programs for early diagnosis and is considered safe and effective. This study aimed to analyze the conceptions of women on cervical cancer screening. A qualitative study was carried out with 30 women assisted in primary care, in Teresina, Piaui, Brazil. The Discourse of the Collective Subject was obtained from interviews carried out from August to October 2016. The speeches expressed the notions that women have about the significance of the screening test, the importance of undergoing the test, and prevention of cervical cancer. The conceptions of the interviewed women revealed that the test prevents diseases, including cervical cancer. However, the discourses left clear the lack of knowledge on HPV, its forms of prevention and cervical cancer. The analysis revealed that women have superficial or insufficient knowledge about the significance of the screening test and cervical cancer.
尽管子宫颈癌的流行率和发病率很高,但如果在早期发现,这种疾病是可以避免的,而且有很大的治愈潜力。宫颈癌筛查用于早期诊断的监测项目,被认为是安全有效的。本研究旨在分析女性对子宫颈癌筛查的观念。在巴西皮奥伊省特雷西纳,对30名妇女进行了一项质量研究,协助她们接受初级保健。集体主体的话语来自于2016年8月至10月的访谈。这些演讲表达了妇女对筛查测试的重要性、接受测试的重要性以及预防宫颈癌的观念。受访妇女的观念表明,该检查可以预防疾病,包括宫颈癌。然而,这些论述清楚地表明,人们对HPV及其预防形式和宫颈癌缺乏了解。分析显示,妇女对筛查试验和宫颈癌的重要性的认识是肤浅的或不足的。
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引用次数: 3
Association between self reports of osteo-articular pain, and functional and clinical indicators on elderly residents in riparian Maués-AM 老年居民骨关节疼痛自我报告与莫扎伊姆河流域老年居民功能和临床指标的关系
Pub Date : 2018-11-30 DOI: 10.4025/ACTASCIHEALTHSCI.V40I0.38999
Tábada Samantha Marques Rosa, E. Ribeiro, K. Mota, E. A. Maia-Ribeiro, I. B. M. Cruz
In Brazil, a large part of the population of elderly people living in rural areas have difficult access to specialized health services. The objective of this study was to evaluate the association between self-reported of osteo-articular pain with functional and clinical indicators on elderly residents in riparian Maues-AM. Was conducted a cross-sectional study, observational who initially estimated the prevalence of osteo-articular pain through self-reporting of the elderly. The elderly the study were selected from families registered in the family health strategy. The questions were applied in the form of a structured interview. Most of the sample was constituted by men, with a prevalence of 64.2% (n = 1159) of seniors who reported some form of osteo-articular pain, being similar among elderly residents in urban region and in Riverside-rural region. Older women were more involved and the elderly over 75 years of age. The elderly with osteo-articular pain showed a significantly higher prevalence of morbidities and considered bad to your health and life. It is necessary to promote public policies for the implementation of programs that target the prevention and control of musculoskeletal diseases. To be able to promote a better functional ability and quality of life for this population.
在巴西,生活在农村地区的很大一部分老年人很难获得专门的保健服务。本研究的目的是评估Maues-AM河岸老年居民自我报告的骨关节疼痛与功能和临床指标之间的关系。进行了一项横断面研究,观察性研究最初通过老年人的自我报告估计骨关节疼痛的患病率。研究中的老年人是从家庭健康战略中登记的家庭中挑选出来的。这些问题以结构化访谈的形式提出。大多数样本由男性组成,报告某种形式的骨关节疼痛的老年人患病率为64.2% (n = 1159),在城市地区和河滨-农村地区的老年居民中相似。老年妇女和75岁以上的老年人参与更多。老年人骨关节疼痛的发病率明显较高,被认为对健康和生活有害。有必要促进公共政策的实施,以预防和控制肌肉骨骼疾病为目标。能够促进更好的功能能力和生活质量的人群。
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引用次数: 0
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