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Towards a Robotically Steerable Laser Ablation Probe. 实现可机器人转向的激光烧蚀探针
Pub Date : 2024-06-01 Epub Date: 2024-07-12 DOI: 10.1109/ismr63436.2024.10586060
Julio Adrian Ceja, Saeed Rezaeian, J Rodrigo Vélez-Cordero, Juan Hernández-Cordero, Behnam Badie, Jun Sheng

In this paper, we present a robotically steerable laser ablation probe with application to interstitial thermal therapy. Existing laser interstitial thermal therapy (LITT) methods utilize a straight probe to deliver laser energy around the tip or to the side of the tip. These methods are inadequate to provide effective treatment for large, irregularly shaped tumors. Our robotic probe can be manipulated inside soft tissue to perform ablation at multiple locations, thus enabling conformable ablation for large and complicated tumors. Instead of directly firing laser into soft tissue, a Polydimethylsiloxane (PDMS)/Carbon nanoparticles (CNPs) mixture hosts a multi-mode optical fiber at the probe tip to work as a heater when laser is activated to improve the procedural safety. This paper presents the design and fabrication of the robotic ablation probe, simulation of laser thermal transformation using finite element analysis, and experimental studies that characterize the robot motion and heating effects and demonstrate in vitro ablation.

在本文中,我们介绍了一种应用于间质热疗的机器人可转向激光烧蚀探头。现有的激光间质热疗(LITT)方法是利用直探针在针尖周围或针尖一侧输送激光能量。这些方法不足以对形状不规则的大型肿瘤进行有效治疗。我们的机器人探针可在软组织内操作,在多个位置进行消融,从而实现对大型复杂肿瘤的适形消融。探针顶端的聚二甲基硅氧烷(PDMS)/碳纳米颗粒(CNPs)混合物不直接向软组织发射激光,而是在激光启动时在探针顶端安装一根多模光纤作为加热器,以提高手术安全性。本文介绍了机器人消融探针的设计和制造、利用有限元分析模拟激光热转换、描述机器人运动和加热效果的实验研究以及体外消融演示。
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引用次数: 0
Artificial intelligence (AI) for minimally invasive robotics 用于微创机器人的人工智能(AI)
B. Maris
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引用次数: 0
Brain-Mimicking Phantom for Photoablation and Visualization. 用于光消融和可视化的脑模拟幻影。
Ravi Prakash, Kent K Yamamoto, Siobhan R Oca, Weston Ross, Patrick J Codd

While the use of tissue-mimicking (TM) phantoms has been ubiquitous in surgical robotics, the translation of technology from laboratory experiments to equivalent intraoperative tissue conditions has been a challenge. The increasing use of lasers for surgical tumor resection has introduced the need to develop a modular, low-cost, functionally relevant TM phantom to model the complex laser-tissue interaction. In this paper, a TM phantom with mechanically and thermally similar properties as human brain tissue suited for photoablation studies and subsequent visualization is developed. The proposed study demonstrates the tuned phantom response to laser ablation for fixed laser power, time, and angle. Additionally, the ablated crater profile is visualized using optical coherence tomography (OCT), enabling high-resolution surface profile generation.

虽然在外科机器人中使用组织模拟(TM)模型已经无处不在,但将技术从实验室实验转化为等效的术中组织条件一直是一个挑战。外科肿瘤切除术中越来越多地使用激光,这就需要开发一种模块化、低成本、功能相关的TM模体来模拟复杂的激光与组织的相互作用。本文开发了一种具有与人脑组织相似的机械和热特性的TM模型,适合于光消融研究和随后的可视化。本研究展示了在固定的激光功率、时间和角度下,可调谐的幻体对激光烧蚀的响应。此外,使用光学相干断层扫描(OCT)可以可视化烧蚀的陨石坑轮廓,从而实现高分辨率的表面轮廓生成。
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引用次数: 0
Optical Fiber -Based Needle Shape Sensing: Three-channel Single Core vs. Multicore Approaches. 基于光纤的针形传感:三通道单核与多核方法。
Alexandra Cheng, Dimitri A Lezcano, Jin Seob Kim, Iulian I Iordachita

Bevel-tip needles are commonly utilized in percutaneous medical interventions where a curved insertion trajectory is required. To avoid deviation from the intended trajectory, needle shape sensing and tip localization is crucial in providing the operator with feedback. There is an abundance of previous work that investigate the medical application of fiber Bragg grating (FBG) sensors, but most works select only one specific type of fiber among the many available sensor options to integrate into their hardware designs. In this work, we compare two different types of FBG sensors under identical conditions and application, namely, acting as the sensor for needle insertion shape reconstruction. We built a three-channel single core needle and a seven-channel multicore fiber (MCF) needle and discuss the pros and cons of both constructions for shape sensing experiments into constant curvature jigs. The overall needle tip error is 1.23 mm for the single core needle and 2.08 mm for the multicore needle.

斜头针通常用于经皮医疗干预,其中需要弯曲的插入轨迹。为了避免偏离预定轨迹,针形传感和针尖定位在向操作员提供反馈方面至关重要。以前有大量研究光纤布拉格光栅(FBG)传感器的医疗应用的工作,但大多数工作只选择一种特定类型的光纤在许多可用的传感器选项中集成到他们的硬件设计中。在这项工作中,我们比较了两种不同类型的FBG传感器在相同的条件和应用下,即作为针插入形状重建的传感器。我们构建了一个三通道单芯针和一个七通道多芯光纤(MCF)针,并讨论了两种结构的优缺点,用于恒曲率夹具的形状传感实验。单芯针的总针尖误差为1.23 mm,多芯针的总针尖误差为2.08 mm。
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引用次数: 1
Delta Robot Kinematic Calibration for Precise Robot-Assisted Retinal Surgery. 精确机器人辅助视网膜手术的Delta机器人运动学标定。
Pub Date : 2022-04-01 Epub Date: 2022-06-28 DOI: 10.1109/ismr48347.2022.9807517
Boyang Xiao, Alireza Alamdar, Kefan Song, Ali Ebrahimi, Peter Gehlbach, Russell H Taylor, Iulian Iordachita

High precision is required for ophthalmic robotic systems. This paper presents the kinematic calibration for the delta robot which is part of the next generation of Steady-Hand Eye Robot (SHER). A linear error model is derived based on geometric error parameters. Two experiments with different ranges of workspace are conducted with laser sensors measuring displacement. The error parameters are identified and applied in the kinematics to compensate for modeling error. To achieve better accuracy, Bernstein polynomials are adopted to fit the error residuals after compensation. After the kinematic calibration process, the error residuals of the delta robot are reduced to satisfy the clinical requirements.

眼科机器人系统要求高精度。介绍了新一代稳手眼机器人(SHER)中的delta机器人的运动学标定方法。建立了基于几何误差参数的线性误差模型。利用激光位移传感器进行了两个不同工作空间范围的实验。辨识误差参数并应用于运动学中以补偿建模误差。为了获得更好的精度,采用Bernstein多项式对补偿后的误差残差进行拟合。经过运动学标定后,delta机器人的误差残差减小,满足临床要求。
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引用次数: 1
Optimization-based Concurrent Control of a High Dexterity Robot for Vitreoretinal Surgery. 基于优化的高灵巧玻璃体视网膜手术机器人并行控制。
Pub Date : 2022-04-01 Epub Date: 2022-06-28 DOI: 10.1109/ismr48347.2022.9807485
Kaiyu Shi, Yishun Zhou, Ali Ebrahimi, Gang Li, Iulian Iordachita

Vitreoretinal surgery requires dexterity and force sensitivity from the clinician. A system to cooperatively control an integrated surgical robot for high dexterity manipulation within the eye's vitreous space was developed and validated in simulation. The system is composed of a 2 degrees of freedom (DoF) snake-like continuum manipulator that is attached to the end-effector of a 5-DoF rigid robot arm. It is capable of receiving position and orientation commands from a 5-DoF input device in real-time, as well as following pre-planned trajectories. The manipulator is moved to each target pose in real-time, using an optimization method to calculate the inverse kinematics solution. Constraints on the position and orientation ensure the target pose does not harm the patient within the vitreous space, enabling the robot to safely assist the clinician with vitreoretinal surgery when operating in real-time. The simulation demonstrates the system's feasibility and benefits over the existing non-dexterous system.

玻璃体视网膜手术需要临床医生的灵活性和力敏感性。开发了一种协同控制集成手术机器人在眼玻璃体空间内进行高灵巧操作的系统,并进行了仿真验证。该系统由一个2自由度(DoF)蛇形连续机械臂组成,该连续机械臂连接在5自由度刚性机械臂的末端执行器上。它能够实时接收来自5自由度输入设备的位置和方向命令,并遵循预先规划的轨迹。机械手实时移动到各个目标位姿,采用优化方法计算运动学逆解。对位置和方向的约束保证了目标姿态不会在玻璃体空间内伤害患者,使机器人能够在实时操作时安全地协助临床医生进行玻璃体视网膜手术。仿真结果表明了该系统的可行性和相对于现有非灵巧系统的优越性。
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引用次数: 0
Modeling and Operator Control of a Robotic Tool for Bidirectional Manipulation in Targeted Prostate Biopsy. 用于前列腺活检双向操作的机器人工具的建模和操作员控制。
Blayton Padasdao, Zolboo Batsaikhan, Samuel Lafreniere, Mahsa Rabiei, Bardia Konh

This work introduces design, manipulation, and operator control of a bidirectional robotic tool for minimally invasive targeted prostate biopsy. The robotic tool is purposed to be used as a compliant flexure section of active biopsy needles. The design of the robotic tool comprises of a flexure section fabricated on a nitinol tube that enables bidirectional bending via actuation of two internal tendons. The statics of the flexure section is presented and validated with experimental data. Finally, the capability of the robotic tool to reach targeted positions inside prostate gland is evaluated.

本工作介绍了用于微创前列腺活检的双向机器人工具的设计、操作和操作员控制。该机器人工具的目的是用作活动活检针的柔性部分。机器人工具的设计包括在镍钛诺管上制造的弯曲部分,通过驱动两个内部肌腱实现双向弯曲。给出了受弯截面的静力学,并用实验数据进行了验证。最后,对机器人工具到达前列腺内目标位置的能力进行了评估。
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引用次数: 3
Steering a Tendon-Driven Needle in High-Dose-Rate Prostate Brachytherapy for Patients with Pubic Arch Interference. 在耻骨弓干扰患者的高剂量前列腺近距离治疗中使用肌腱驱动针。
Bardia Konh, Blayton Padasdao, Zolboo Batsaikhan, John Lederer

High-dose-rate brachytherapy (HDR BT) is a radiation therapy that places radioactive sources at cancerous tissue using needles. HDR BT offers better dose conformality and sparing of clinical structures, lower operator dependency, and fewer acute irritative symptoms compared to the other form of BT (low-dose-rate (LDR)). However, use of HDR BT is limited for patients with pubic arch interference, where the transperineal path to the prostate is blocked. This study aims to introduce a tendon-driven needle that can bend inside tissue to reach desired positions inside prostate. Initial experiments in a phantom tissue showed the feasibility of the needle to get around the pubic arch for placement at hard-to-reach target positions.

高剂量率近距离放射疗法(HDR BT)是一种使用针头将放射源放置在癌组织上的放射疗法。与其他形式的BT(低剂量率(LDR))相比,HDR BT具有更好的剂量一致性和节省临床结构、更低的操作者依赖性和更少的急性刺激症状。然而,对于有耻骨弓干扰的患者,经会阴到前列腺的路径被阻断,HDR BT的使用是有限的。这项研究旨在引入一种肌腱驱动的针,它可以在组织内部弯曲,达到前列腺内部所需的位置。在幻体组织中进行的初步实验表明,针可以绕过耻骨弓,放置在难以到达的目标位置。
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引用次数: 5
NeuroPlan: A Surgical Planning Toolkit for an MRI-Compatible Stereotactic Neurosurgery Robot. NeuroPlan: mri兼容立体定向神经外科机器人的手术计划工具包。
Pub Date : 2021-11-01 Epub Date: 2022-01-03 DOI: 10.1109/ismr48346.2021.9661581
Farid Tavakkolmoghaddam, Dhruv Kool Rajamani, Benjamin Szewczyk, Zhanyue Zhao, Katie Gandomi, Shreyas Chandra Sekhar, Julie Pilitsis, Christopher Nycz, Gregory Fischer

The adoption of robotic image-guided surgeries has enabled physicians to perform therapeutic and diagnostic procedures with less invasiveness and higher accuracy. One example is the MRI-guided stereotactic robotic-assisted surgery for conformal brain tumor ablation, where the robot is used to position and orient a thin probe to target a desired region within the brain. Requirements such as the remote center of motion and precise manipulation, impose the use of complex kinematic structures, which result in non-trivial workspaces in these robots. The lack of workspace visualization poses a challenge in selecting valid entry and target points during the surgical planning and navigation stage. In this paper, we present a surgical planning toolkit called the "NeuroPlan" for our MRI-compatible stereotactic neurosurgery robot developed as a module for 3D Slicer software. This toolkit streamlines the current surgical workflow by rendering and overlaying the robot's reachable workspace on the MRI image. It also assists with identifying the optimal entry point by segmenting the cranial burr hole volume and locating its center. We demonstrate the accuracy of the workspace rendering and burr hole parameter detection through both phantom and MR-images acquired from previously conducted animal studies.

采用机器人图像引导手术使医生能够以更小的侵入性和更高的准确性进行治疗和诊断过程。一个例子是mri引导的立体定向机器人辅助手术,用于适形脑肿瘤消融,其中机器人用于定位和定向薄探针,以瞄准大脑内所需的区域。诸如远程运动中心和精确操作等要求,强制使用复杂的运动学结构,这导致这些机器人的工作空间不平凡。在手术计划和导航阶段,缺乏可视化的工作空间对选择有效的进入点和目标点提出了挑战。在本文中,我们提出了一个名为“NeuroPlan”的手术计划工具包,用于我们的mri兼容立体定向神经外科机器人,作为3D切片器软件的模块开发。该工具包通过在MRI图像上渲染和覆盖机器人可到达的工作空间,简化了当前的手术工作流程。它还有助于通过分割颅骨毛刺孔体积和定位其中心来确定最佳切入点。我们通过从先前进行的动物研究中获得的幻影和核磁共振图像证明了工作空间渲染和毛刺孔参数检测的准确性。
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引用次数: 2
Towards a Clinically Optimized Tilt Mechanism for Bilateral Micromanipulation with Steady-Hand Eye Robot. 一种临床优化的手眼机器人双侧显微操作倾斜机制。
Robert Roth, Jiahao Wu, Alireza Alamdar, Russell H Taylor, Peter Gehlbach, Iulian Iordachita

Cooperative robotic systems for vitreoretinal surgery can enable novel surgical approaches by allowing the surgeon to perform procedures with enhanced stabilization and high accuracy tool movements. This paper presents the optimization and design of a four-bar linkage type tilt mechanism for a novel Steady-Hand Eye Robot (SHER) which can be used equivalently on both, the left and right patient side, during a bilateral approach with two robots. In this optimization, it is desirable to limit the workspace needed for compensation motions that ensure a virtual remote center of motion (V-RCM). The safety space around the patient, the space for the surgeon's hand and maintaining positional accuracy are also included in the optimization. The applicability of the resulting optimized mechanism was confirmed with a design prototype in a representative mock-up of the surgical setting allowing multiple directions of robot approach towards a medical phantom.

用于玻璃体视网膜手术的协作机器人系统可以通过允许外科医生在增强稳定性和高精度工具运动的情况下执行手术,从而实现新的手术方法。本文介绍了一种新型的稳定手眼机器人(SHER)的四杆连杆式倾斜机构的优化设计,该机构可以在两个机器人的双边接近过程中在患者的左右侧等效使用。在此优化中,希望限制补偿运动所需的工作空间,以确保虚拟远程运动中心(V-RCM)。患者周围的安全空间,外科医生的手的空间和保持位置精度也包括在优化中。在一个具有代表性的外科环境模型中,通过一个设计原型验证了所得到的优化机构的适用性,该模型允许机器人向医疗幻影的多个方向靠近。
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引用次数: 2
期刊
... International Symposium on Medical Robotics. International Symposium on Medical Robotics
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