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Purely Endoscopic Treatment for Arachnoid Cysts. 蛛网膜囊肿的纯内窥镜治疗。
Pub Date : 2024-01-01 DOI: 10.1007/978-3-031-61925-0_8
Joachim Oertel, Karen Radtke

Arachnoid cysts are benign, mostly congenital lesions that are asymptomatic in most patients. In some cases, due to their location or sheer size, they produce a mass effect or hydrocephalic obstruction of the cerebrospinal fluid (CSF) flow and thus might warrant surgical treatment. The goal of the surgery is usually to reduce pressure inside the cysts, to reduce the mass effect, or to restore the CSF pathway. Surgical treatment options are resection, fenestration, or shunting of the cyst. Over the past decades, treatment under sheer endoscopic control either through a tube or via craniotomy of arachnoid cysts has been studied thoroughly and replaced open microsurgical cyst surgery in the opinion of many neurosurgeons. Endoscopic treatment has proven to be a safe and feasible technique for both patients and surgeons. In the following chapter, the authors describe their indications for surgery and pre- and postoperative workup, where precautions should be taken, and discuss the different possibilities and techniques of endoscopic cyst fenestration. The aim is to give detailed instructions and present cases for ventriculocystostomy, cystocisternostomy, ventriculocystocisternostomy, and cystoventriculostomy and point out specifics deemed to be important to avoid complications and to ensure the best possible outcome for each patient.

蛛网膜囊肿是一种良性病变,多为先天性,大多数患者无症状。在某些情况下,由于囊肿的位置或体积过大,会产生肿块效应或脑积水,导致脑脊液(CSF)流动受阻,因此可能需要进行手术治疗。手术的目的通常是降低囊肿内的压力、减轻肿块效应或恢复 CSF 通路。手术治疗方法有囊肿切除术、囊肿切开术或囊肿分流术。在过去的几十年中,许多神经外科医生对纯粹在内窥镜控制下通过插管或开颅手术治疗蛛网膜囊肿的方法进行了深入研究,并认为这种方法取代了开颅显微囊肿手术。事实证明,内窥镜治疗对患者和外科医生来说都是一种安全可行的技术。在接下来的章节中,作者介绍了手术的适应症、术前术后的准备工作、术前术后的注意事项,并讨论了内镜下囊肿穿孔的各种可能性和技术。目的是详细说明和介绍脑室膀胱造口术、膀胱胆囊造口术、脑室膀胱胆囊造口术和膀胱胆囊造口术的病例,并指出避免并发症和确保每位患者获得最佳治疗效果的重要细节。
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引用次数: 0
Endoscopic Eyebrow Approach for Aneurysms. 内窥镜眉部动脉瘤手术
Pub Date : 2024-01-01 DOI: 10.1007/978-3-031-61925-0_12
Gerrit Fischer, Joachim Oertel

Introduction: Considerable effort has been made to reduce surgical invasiveness, since Axel Perneczky introduced the supraorbital eyebrow approach as a core part of his keyhole concept in neurosurgery. But a limited approach does not facilitate an already serious and demanding task as aneurysm surgery. In this regard, the enhancement of the visual field before, during, and after microsurgical aneurysm occlusion is a safe and effective method to increase the quality of treatment. Indications/Contraindications: Based on the individual anatomical findings, the supraorbital keyhole approach provides access to most aneurysms of the anterior circulation. The approach is not recommended in large complex aneurysms, giant aneurysms, BA aneurysms located beneath the dorsum sellae, as well as cases of severe subarachnoid hemorrhage (SAH) and expected brain edema.

Complications: Experience with endoscopic procedures in aneurysm surgery is limited to several clinical retrospective articles, and no major complications in conjunction with the endoscope were observed. Outcome and Prognosis: The supraorbital eyebrow approach has a low rate of complications and provides highly favorable cosmetic results. Endoscopic inspection prior to clipping might reduce overexposure and mobilization of the aneurysm. It was found that the rate of intraoperative rupture was decreased. The endoscopic post-clipping control helped significantly to reduce aneurysm remnants and unattended parent, branch, or perforator occlusion.

Conclusion: The supraorbital eyebrow approach is a safe, effective and elegant approach in the treatment of most aneurysms of the anterior circulation. The additional enhancement of the visual field provided by the endoscope before, during, and after microsurgical aneurysm clipping might decrease the rate of intraoperative aneurysm ruptures and unexpected findings concerning aneurysm remnant occlusion and compromise of involved parent, branching, and perforating vessels.

导言:自 Axel Perneczky 将眶上眉入路作为其神经外科锁孔概念的核心部分以来,人们一直在为减少手术创口做出巨大努力。但是,对于动脉瘤手术这种本已十分严肃和艰巨的任务来说,有限的入路并不利于手术的顺利进行。因此,在显微外科动脉瘤闭塞术前、术中和术后增强视野是提高治疗质量的一种安全有效的方法。适应症/禁忌症:根据个人的解剖学发现,眶上锁孔方法可进入大多数前循环动脉瘤。大型复杂动脉瘤、巨大动脉瘤、位于蝶鞍背下方的 BA 动脉瘤以及严重蛛网膜下腔出血(SAH)和预期脑水肿病例不建议采用这种方法:内窥镜动脉瘤手术的经验仅限于几篇临床回顾性文章,未观察到与内窥镜相关的重大并发症。结果和预后:眶上眉毛法的并发症发生率较低,并能提供良好的美容效果。剪切前进行内窥镜检查可减少动脉瘤的过度暴露和移动。研究发现,术中破裂率有所降低。内镜下的剪切后控制大大有助于减少动脉瘤残余和未处理的母动脉、分支或穿孔器闭塞:结论:眶上眉方法是治疗大多数前循环动脉瘤的一种安全、有效和优雅的方法。内窥镜在显微外科动脉瘤剪切术前、术中和术后提供的额外视野增强功能,可能会降低术中动脉瘤破裂率以及动脉瘤残余闭塞和受累母血管、分支血管和穿孔血管受损的意外发现率。
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引用次数: 0
Comparative Optics of the Surgical Microscope and Rigid Endoscopes in Neurosurgery. 神经外科手术显微镜和刚性内窥镜的光学比较。
Pub Date : 2024-01-01 DOI: 10.1007/978-3-031-61925-0_1
Athary Saleem, Nathan S Chisvo, Waleed Yousef, Waleed Abdelfattah Azab

This chapter is intended to provide a brief overview of the optics of surgical microscopes and rigid endoscopes, with the aim of providing the reader with the principles dictating the nature of surgical visualization when either of the visual control systems is used. It is not by any means geared toward elaborating on the detailed optical physics of these systems, which is beyond the scope and objective of this chapter.

本章旨在简要概述手术显微镜和硬质内窥镜的光学原理,目的是向读者介绍在使用这两种视觉控制系统时,决定手术可视化性质的原理。本章绝不是为了详细阐述这些系统的光学物理原理,因为这超出了本章的范围和目的。
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引用次数: 0
Diagnosis and Management of Tethered Cord Syndrome. 系索综合症的诊断和管理。
Pub Date : 2024-01-01 DOI: 10.1007/978-3-031-42398-7_3
Takeshi Hara, Yukoh Ohara, Akihide Kondo

Tethered cord syndrome is a condition in which the spinal cord is tethered by pathological structures such as a tight filum terminale, intradural lipomas with or without a connecting extradural component, intradural fibrous adhesions, diastematomyelia, and neural placode adhesions following closure of a myelomeningocele.It usually occurs in childhood and adolescence as the spine grows in length, but it can also develop in adulthood. Symptoms of tethered cord syndrome are slowly progressive and varied. Incorrect diagnosis and inappropriate treatment may be provided if the physician lacks knowledge and understanding of this disease.This chapter aims to describe the pathophysiology, syndromes, diagnostic imaging, surgical treatment, and prognosis of tethered cord syndrome to enhance the understanding of this condition.

拴系脊髓综合征是指脊髓被一些病理结构拴系的情况,这些病理结构包括脊髓末端丝膜过紧、硬膜内脂肪瘤(伴有或不伴有硬膜外连接成分)、硬膜内纤维粘连、脊髓脊膜膨出以及脊髓脊膜膨出闭合后的神经胎盘粘连。系索综合征的症状缓慢进展且多种多样。本章旨在描述系带综合征的病理生理学、综合征、影像诊断、手术治疗和预后,以加深对这种疾病的了解。
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引用次数: 0
The Value of Intraoperative Ultrasound in Brain Surgery. 术中超声波在脑外科手术中的价值。
Pub Date : 2024-01-01 DOI: 10.1007/978-3-031-53578-9_6
Mohamed A El Beltagy, Mohammad Elbaroody

Favorable clinical outcomes in adult and pediatric neurosurgical oncology generally depend on the extent of tumor resection (EOR). Maximum safe resection remains the main aim of surgery in most intracranial tumors. Despite the accuracy of intraoperative magnetic resonance imaging (iMRI) in the detection of residual intraoperatively, it is not widely implemented worldwide owing to enormous cost and technical difficulties. Over the past years, intraoperative ultrasound (IOUS) has imposed itself as a valuable and reliable intraoperative tool guiding neurosurgeons to achieve gross total resection (GTR) of intracranial tumors.Being less expensive, feasible, doesn't need a high level of training, doesn't need a special workspace, and being real time with outstanding temporal and spatial resolution; all the aforementioned advantages give a superiority for IOUS in comparison to iMRI during resection of brain tumors.In this chapter, we spot the light on the technical nuances, advanced techniques, outcomes of resection, pearls, and pitfalls of the use of IOUS during the resection of brain tumors.

成人和儿童神经肿瘤外科的临床疗效通常取决于肿瘤切除范围(EOR)。最大程度的安全切除仍然是大多数颅内肿瘤手术的主要目标。尽管术中磁共振成像(iMRI)在检测术中残留方面具有很高的准确性,但由于成本高昂和技术难度大,在全球范围内并未得到广泛应用。在过去几年中,术中超声(IOUS)已成为指导神经外科医生实现颅内肿瘤全切(GTR)的重要而可靠的术中工具。在本章中,我们将揭示在脑肿瘤切除术中使用 IOUS 的技术细节、先进技术、切除结果、珍珠和陷阱。
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引用次数: 0
Intraventricular Tumors: Surgical Considerations in Lateral and Third Ventricular Tumors. 室管膜内肿瘤:侧脑室和第三脑室肿瘤的手术注意事项。
Pub Date : 2024-01-01 DOI: 10.1007/978-3-031-53578-9_3
Chandrashekhar Deopujari, Krishna Shroff, Suhas Malineni, Salman Shaikh, Chandan Mohanty, Vikram Karmarkar, Amol Mittal

Management of lateral and third ventricular tumors has been a challenge for neurosurgeons. Advances in imaging and pathology have helped in a better understanding of the treatment options. Technical refinement of microsurgical technique and addition of endoscopy has enabled more radical excision of tumors, when indicated, and added more safety.A proper understanding of the pathology at various ages and treatment options is continuously evolving. Many pediatric tumors are amenable to conservative surgical methods with effective complementary treatments. However, radical surgery is required in many adults as the main treatment and for many benign tumors. Various intraventricular lesions encountered and their surgical management is reviewed here for their efficacy, safety, and outcome, encompassing changes in our practice over the last 20 years.

侧脑室和第三脑室肿瘤的治疗一直是神经外科医生面临的挑战。影像学和病理学的进步有助于更好地了解治疗方案。显微外科技术的改进和内窥镜的加入,使肿瘤在必要时可以进行更彻底的切除,并增加了安全性。对不同年龄病理和治疗方案的正确理解在不断发展。许多小儿肿瘤可以采用保守的手术方法和有效的辅助治疗。然而,许多成人肿瘤和良性肿瘤则需要根治性手术作为主要治疗手段。本文回顾了所遇到的各种脑室内病变及其手术治疗的疗效、安全性和结果,包括过去20年中我们在实践中的变化。
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引用次数: 0
Molecular Biomarkers Affecting Moyamoya Disease. 影响莫亚莫亚病的分子生物标记物
Pub Date : 2024-01-01 DOI: 10.1007/978-3-031-42398-7_1
Yong-Kwang Tu, Yao-Ching Fang

Although the pathogenetic pathway of moyamoya disease (MMD) remains unknown, studies have indicated that variations in the RING finger protein RNF 213 is the strongest susceptible gene of MMD. In addition to the polymorphism of this gene, many circulating angiogenetic factors such as growth factors, vascular progenitor cells, inflammatory and immune mediators, angiogenesis related cytokines, as well as circulating proteins promoting intimal hyperplasia, excessive collateral formation, smooth muscle migration and atypical migration may also play critical roles in producing this disease. Identification of these circulating molecules biomarkers may be used for the early detection of this disease. In this chapter, how the hypothesized pathophysiology of these factors affect MMD and the interactive modulation between them are summarized.

尽管莫亚莫亚病(MMD)的发病机制尚不清楚,但研究表明,RING 手指蛋白 RNF 213 的变异是莫亚莫亚病的最强易感基因。除了该基因的多态性外,许多循环血管生成因子,如生长因子、血管祖细胞、炎症和免疫介质、与血管生成相关的细胞因子,以及促进内膜增生、过度侧支形成、平滑肌迁移和非典型迁移的循环蛋白,也可能在该病的发生中发挥关键作用。识别这些循环分子生物标志物可用于早期检测这种疾病。本章将总结这些因素的假设病理生理学如何影响 MMD 以及它们之间的交互调节。
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引用次数: 0
Evaluation and Treatment of Patients with Small Posterior Cranial Fossa and Chiari Malformation, Types 0 and 1. 小后颅窝和奇拉氏畸形(0 型和 1 型)患者的评估和治疗。
Pub Date : 2024-01-01 DOI: 10.1007/978-3-031-53578-9_11
Enver I Bogdanov, John D Heiss

The diagnosis of Chiari I malformation is straightforward in patients with typical signs and symptoms of Chiari I malformation and magnetic resonance imaging (MRI) confirming ≥5 mm of cerebellar tonsillar ectopia, with or without a syrinx. However, in many cases, Chiari I malformation is discovered incidentally on MRI to evaluate global headache, cervical radiculopathy, or other conditions. In those cases, the clinician must consider if cerebellar tonsillar ectopia is related to the presenting symptoms. Surgical decompression of the cerebellar tonsils and foramen magnum in patients with symptomatic Chiari I malformation effectively relieves suboccipital headache, reduces syrinx distension, and arrests syringomyelia progression. Neurosurgeons must avoid operative treatments decompressing incidental tonsillar ectopia, not causing symptoms. Such procedures unnecessarily place patients at risk of operative complications and tissue injuries related to surgical exploration. This chapter reviews the typical signs and symptoms of Chiari I malformation and its variant, Chiari 0 malformation, which has <5 mm of cerebellar tonsillar ectopia and is often associated with syringomyelia. Chiari I and Chiari 0 malformations are associated with incomplete occipital bone development, reduced volume and height of the posterior fossa, tonsillar ectopia, and compression of the neural elements and cerebrospinal fluid (CSF) pathways at the foramen magnum. Linear, angular, cross-sectional area, and volume measurements of the posterior fossa, craniocervical junction, and upper cervical spine identify morphometric abnormalities in Chiari I and Chiari 0 malformation patients. Chiari 0 patients respond like Chiari I patients to foramen magnum decompression and should not be excluded from surgical treatment because their tonsillar ectopia is <5 mm. The authors recommend the adoption of diagnostic criteria for Chiari 0 malformation without syringomyelia. This chapter provides updated information and guidance to the physicians managing Chiari I and Chiari 0 malformation patients and neuroscientists interested in Chiari malformations.

如果患者有 Chiari I 畸形的典型症状和体征,磁共振成像(MRI)证实小脑扁桃体异位≥5 毫米,伴有或不伴有鞘膜积液,则可直接诊断为 Chiari I 畸形。然而,在许多病例中,Chiari I 畸形是在磁共振成像中偶然发现的,当时是为了评估全局性头痛、颈椎病或其他疾病。在这种情况下,临床医生必须考虑小脑扁桃体异位是否与出现的症状有关。对有症状的 Chiari I 畸形患者进行小脑扁桃体和枕骨大孔减压手术可有效缓解枕下头痛、减轻鞘膜膨出并阻止鞘膜积液的发展。神经外科医生必须避免对未引起症状的偶然扁桃体异位进行手术减压。此类手术会不必要地将患者置于手术并发症和手术探查相关组织损伤的风险之中。本章回顾了Chiari I畸形及其变异型Chiari 0畸形的典型症状和体征。
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引用次数: 0
Anatomical Features of the Ventricular System Relevant to Endoscopic Surgery for Hydrocephalus. 与脑积水内窥镜手术相关的脑室系统解剖学特征。
Pub Date : 2024-01-01 DOI: 10.1007/978-3-031-67077-0_4
Kenichi Nishiyama

In endoscopic surgery for hydrocephalus and associated intraventricular lesions, a thorough understanding of the required microsurgical anatomy is paramount. Endoscopic procedures in hydrocephalus treatment typically fall into two categories: ventriculocisternostomy and ventriculostomy for obstructive hydrocephalus. In the former, precise knowledge of intraventricular structures, such as the configuration of the ventricles and the path of internal vessels within them, is essential. In the latter, a comprehensive grasp of neural pathways, neural nuclei, and especially venous pathways beneath the ventricular wall is crucial for surgical success. Given that many cases exhibit deviations from normal anatomy, careful examination of preoperative images and a solid understanding of anatomical landmarks during surgery are indispensable. This is particularly critical in endoscopic procedures, which may lack stereoscopic vision, underscoring the importance of acquiring visual cues during the surgical intervention.

在脑积水和相关脑室内病变的内窥镜手术中,透彻了解所需的显微外科解剖结构至关重要。治疗脑积水的内窥镜手术通常分为两类:脑室造口术和脑室造口术治疗梗阻性脑积水。前者必须精确了解脑室内结构,如脑室的构造和脑室内血管的走向。对于后者,全面掌握脑室壁下的神经通路、神经核,尤其是静脉通路是手术成功的关键。鉴于许多病例都与正常解剖结构存在偏差,因此在手术过程中仔细检查术前图像和扎实了解解剖标志是必不可少的。这一点在内窥镜手术中尤为重要,因为内窥镜手术可能缺乏立体视觉,这就强调了在手术过程中获取视觉线索的重要性。
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引用次数: 0
Surgical and Medical Management of Pediatric Spine Trauma. 小儿脊柱创伤的外科和内科治疗。
Pub Date : 2024-01-01 DOI: 10.1007/978-3-031-67077-0_11
Amy Baohan, Benjamin Konigsberg, Juan Carlos Rodriguez-Olaverri, Richard C E Anderson

Pediatric spine trauma is rare but presents unique challenges to clinical management. Special considerations include but are not limited to the need to minimize ionizing radiation in this patient population, anatomic immaturity, physiologic variants, and injuries seen only in the pediatric population. Here we review the epidemiology of pediatric spine trauma, presentation, diagnosis, and treatment of the most common injuries and discuss specific medical and surgical strategies for treatment.

小儿脊柱创伤十分罕见,但给临床治疗带来了独特的挑战。需要特别考虑的因素包括但不限于尽量减少电离辐射、解剖结构不成熟、生理变异以及仅在儿科人群中出现的损伤。在此,我们回顾了小儿脊柱创伤的流行病学、最常见损伤的表现、诊断和治疗,并讨论了具体的内外科治疗策略。
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引用次数: 0
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Advances and technical standards in neurosurgery
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