Pub Date : 2024-08-01DOI: 10.1016/j.xagr.2024.100384
Alesha White MD , Macy Afsari , Harini Balakrishnan , Emilia Chapa , Meredith Kim , Shubhangi Mehra , Mary Ann Faucher PhD, CNM, FACNM , Joyce Miller DNP, APRN, WHNP-BC , Polly Cordova DNP, APRN, CNM , Elaine L. Duryea MD , David B. Nelson MD , Anne M. Ambia MD , Donald D. Mcintire PhD , Emily H. Adhikari MD
<div><h3>Objective</h3><p>Screening questionnaires are one option for identification of at-risk substance use and substance use disorder (SUD) during pregnancy. We report the experience of a single institution following universal implementation of a brief screening tool for self-reported substance use at the first prenatal encounter.</p></div><div><h3>Study Design</h3><p>This is a prospective implementation study evaluating screening for substance use in pregnancy in a large safety net healthcare system. Universal screening with the National Institute of Drug Abuse (NIDA) Quick Screen V1.0 was integrated into the electronic medical record (EMR) and administered at the first point of contact with the healthcare system. SUD was identified initially with diagnosis within the EMR by a healthcare provider and was confirmed with toxicology (maternal or neonatal) results corroborating a pattern of substance use and maternal and neonatal ICD-10 codes for SUD. Patients identified with SUD were then classified as moderate or severe SUD based on criteria established by the Diagnostic and Statistical Manual of Mental Disorders, 5th edition. We measured rates of NIDA implementation across different healthcare settings, evaluated NIDA concordance with ascertainment of SUD, and compared adverse pregnancy outcomes associated with moderate and severe SUD.</p></div><div><h3>Results</h3><p>From July 28, 2021, through June 25, 2022, 14,634 unique pregnant individuals accessed care at ambulatory and acute care sites. Universal implementation of the NIDA Quick Screen identified at-risk substance use in 2146 (14.7%) of those who accessed our system, or 17.1% of 12,550 screened across the system, with greater screen completion in ambulatory over acute care settings. SUD was identified in 256 (1.7%) of 14,634 individuals and moderate or severe SUD was identified in 184 (1.3%). Among those with moderate or severe SUD, 90 (48.9%) were NIDA positive, 22 (12.0%) NIDA negative, and 72 (39.1%) unscreened. Of 94 individuals with NIDA discordance or who were unscreened 76 (81%) accessed initial care through an acute care setting. Of 96 individuals with opioid use disorder, 68 (70.8%) were treated with medication-assisted therapy, and 56 (58.3%) were screened with the NIDA Quick Screen. Among delivered individuals with available outcomes, those with moderate or severe SUD were less likely to seek prenatal care (71 (76%) vs 9852 (98%), <0.001)) and more likely to deliver before 37 weeks, (18 (20%) vs 909 (9%), RR (95% CI) 2.13 (1.40, 3.24)) compared to individuals without SUD. Neonates exposed to moderate or severe SUD were more likely to have birth weight <10th centile for gestational age (20 (22%) vs 1147 (12%), RR (95% CI) 1.92 (1.29, 2.85)) and require admission to the neonatal intensive care unit (NICU) (19 (21%) vs 964 (10%), RR (95%) 1.95 (1.30, 2.93)).</p></div><div><h3>Conclusion</h3><p>Universal screening was implemented across a large public healthcare system at a
目的筛查问卷是识别孕期药物使用风险和药物使用障碍(SUD)的一种方法。研究设计这是一项前瞻性实施研究,评估了大型安全网医疗保健系统对孕期药物使用情况的筛查。美国国家药物滥用研究所(NIDA)的快速筛查 V1.0 被整合到电子病历(EMR)中,并在与医疗保健系统的首次接触时进行普遍筛查。通过医疗服务提供者在 EMR 中的诊断初步确定 SUD,并通过证实药物使用模式的毒理学(孕产妇或新生儿)结果以及孕产妇和新生儿 SUD 的 ICD-10 编码进行确认。然后,根据《精神疾病诊断与统计手册》第 5 版制定的标准,将确定为 SUD 的患者划分为中度或重度 SUD。我们测量了不同医疗机构的 NIDA 实施率,评估了 NIDA 与 SUD 确定的一致性,并比较了与中度和重度 SUD 相关的不良妊娠结局。在使用我们系统的人中,有 2146 人(14.7%)通过普遍实施 NIDA 快速筛查发现有药物使用风险,占整个系统筛查的 12,550 人的 17.1%,非住院医疗机构的筛查完成率高于急诊医疗机构。在 14634 人中,有 256 人(1.7%)被确认患有药物滥用症,184 人(1.3%)被确认患有中度或重度药物滥用症。在中度或重度 SUD 患者中,90 人(48.9%)NIDA 阳性,22 人(12.0%)NIDA 阴性,72 人(39.1%)未接受筛查。在 94 名 NIDA 不一致或未经筛查的患者中,有 76 人(81%)通过急症护理机构获得了初步护理。在 96 名阿片类药物使用障碍患者中,68 人(70.8%)接受了药物辅助治疗,56 人(58.3%)接受了 NIDA 快速筛查。与无阿片类药物滥用症的患者相比,有中度或重度阿片类药物滥用症的患者不太可能寻求产前护理(71 (76%) vs 9852 (98%),<0.001)),而且更有可能在 37 周前分娩(18 (20%) vs 909 (9%),RR (95% CI) 2.13 (1.40, 3.24))。接触中度或重度 SUD 的新生儿出生体重超过胎龄第 10 百分位数的几率更高(20 (22%) vs 1147 (12%),RR (95% CI) 1.92 (1.29, 2.85)),需要入住新生儿重症监护室(NICU)的几率更高(19 (21%) vs 964 (10%),RR (95%) 1.结论在一个大型公共医疗系统中,普遍筛查的实施率很高,在门诊环境中的实施率更高。在 17% 的 SUD 群体中,NIDA 成功识别了高危药物使用,但未能识别 50% 以上的中度或重度 SUD 患者。中度和重度 SUD 患者主要通过急诊科接受治疗,产科和新生儿不良后果发生率较高。今后需要努力识别、参与并留住这一最高风险群体。
{"title":"Implementation of universal screening for substance use in pregnancy in a public healthcare system","authors":"Alesha White MD , Macy Afsari , Harini Balakrishnan , Emilia Chapa , Meredith Kim , Shubhangi Mehra , Mary Ann Faucher PhD, CNM, FACNM , Joyce Miller DNP, APRN, WHNP-BC , Polly Cordova DNP, APRN, CNM , Elaine L. Duryea MD , David B. Nelson MD , Anne M. Ambia MD , Donald D. Mcintire PhD , Emily H. Adhikari MD","doi":"10.1016/j.xagr.2024.100384","DOIUrl":"10.1016/j.xagr.2024.100384","url":null,"abstract":"<div><h3>Objective</h3><p>Screening questionnaires are one option for identification of at-risk substance use and substance use disorder (SUD) during pregnancy. We report the experience of a single institution following universal implementation of a brief screening tool for self-reported substance use at the first prenatal encounter.</p></div><div><h3>Study Design</h3><p>This is a prospective implementation study evaluating screening for substance use in pregnancy in a large safety net healthcare system. Universal screening with the National Institute of Drug Abuse (NIDA) Quick Screen V1.0 was integrated into the electronic medical record (EMR) and administered at the first point of contact with the healthcare system. SUD was identified initially with diagnosis within the EMR by a healthcare provider and was confirmed with toxicology (maternal or neonatal) results corroborating a pattern of substance use and maternal and neonatal ICD-10 codes for SUD. Patients identified with SUD were then classified as moderate or severe SUD based on criteria established by the Diagnostic and Statistical Manual of Mental Disorders, 5th edition. We measured rates of NIDA implementation across different healthcare settings, evaluated NIDA concordance with ascertainment of SUD, and compared adverse pregnancy outcomes associated with moderate and severe SUD.</p></div><div><h3>Results</h3><p>From July 28, 2021, through June 25, 2022, 14,634 unique pregnant individuals accessed care at ambulatory and acute care sites. Universal implementation of the NIDA Quick Screen identified at-risk substance use in 2146 (14.7%) of those who accessed our system, or 17.1% of 12,550 screened across the system, with greater screen completion in ambulatory over acute care settings. SUD was identified in 256 (1.7%) of 14,634 individuals and moderate or severe SUD was identified in 184 (1.3%). Among those with moderate or severe SUD, 90 (48.9%) were NIDA positive, 22 (12.0%) NIDA negative, and 72 (39.1%) unscreened. Of 94 individuals with NIDA discordance or who were unscreened 76 (81%) accessed initial care through an acute care setting. Of 96 individuals with opioid use disorder, 68 (70.8%) were treated with medication-assisted therapy, and 56 (58.3%) were screened with the NIDA Quick Screen. Among delivered individuals with available outcomes, those with moderate or severe SUD were less likely to seek prenatal care (71 (76%) vs 9852 (98%), <0.001)) and more likely to deliver before 37 weeks, (18 (20%) vs 909 (9%), RR (95% CI) 2.13 (1.40, 3.24)) compared to individuals without SUD. Neonates exposed to moderate or severe SUD were more likely to have birth weight <10th centile for gestational age (20 (22%) vs 1147 (12%), RR (95% CI) 1.92 (1.29, 2.85)) and require admission to the neonatal intensive care unit (NICU) (19 (21%) vs 964 (10%), RR (95%) 1.95 (1.30, 2.93)).</p></div><div><h3>Conclusion</h3><p>Universal screening was implemented across a large public healthcare system at a","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"4 3","pages":"Article 100384"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666577824000789/pdfft?md5=f18b439e9878396139ed787ccfd877cc&pid=1-s2.0-S2666577824000789-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141852055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-08-01DOI: 10.1016/j.xagr.2024.100378
Rachel J. Tang DO , Leah M. Bode BS , Kyle M. Baugh MD , Kelly M. Mosesso MA , Joanne K. Daggy PhD , David M. Guise MSc, MPH , Evgenia Teal MA , Megan A. Christman DO , Britney N. Tuskan DO , David M. Haas MD, MS
Background
Previous studies that suggest a shorter time from cervical ripening balloon placement to delivery with shorter total balloon placement time have excluded patients with prior cesarean deliveries.
Objective
To evaluate, in patients with a prior history of cesarean delivery undergoing cervical ripening with a double-balloon catheter, whether planned removal of device after 6 vs 12 hours would result in shorter time to vaginal delivery.
Study Design
A before-and-after study was performed after a practice change occurred November 2020, shortening the planned time of double-balloon catheter placement for cervical ripening from 12 to 6 hours. Data were collected via retrospective electronic chart review. Primary outcome was time from balloon placement to vaginal delivery. Secondary outcomes included rates of cesarean delivery, maternal intraamniotic infection, and uterine rupture. Kaplan–Meier curves compared median times to delivery between the groups. A Cox proportional-hazards model was used to adjust for time of balloon placement, number of previous vaginal deliveries, and co-medications used.
Results
From November 2018 to November 2022, 189 analyzable patients with a prior history of cesarean delivery received a double-balloon catheter for cervical ripening during their trial of labor. Patients were separated into pre- and postpolicy change groups (n=91 and 98, respectively). The median time to vaginal delivery for the pregroup was 28 hours (95% CI: 26, 35) and 25 hours (95% CI: 23, 29) for those in the postgroup (P value .052). After adjusting for dilation at time of balloon placement, number of previous vaginal deliveries, and co-medication, the estimated hazard ratio for successful vaginal delivery postpolicy change was 1.89 (95% CI: 1.27, 2.81). There were no differences in rates of secondary outcomes.
Conclusion
In patients with prior cesarean delivery undergoing mechanical cervical ripening with a double-balloon catheter, planned removal at 6 hours compared to 12 hours may result in higher chances of successful vaginal delivery and possibly a shorter time to delivery, without increasing rates of cesarean delivery and intraamniotic infection.
{"title":"Duration of double balloon catheter for patients with prior cesarean: a before and after study","authors":"Rachel J. Tang DO , Leah M. Bode BS , Kyle M. Baugh MD , Kelly M. Mosesso MA , Joanne K. Daggy PhD , David M. Guise MSc, MPH , Evgenia Teal MA , Megan A. Christman DO , Britney N. Tuskan DO , David M. Haas MD, MS","doi":"10.1016/j.xagr.2024.100378","DOIUrl":"10.1016/j.xagr.2024.100378","url":null,"abstract":"<div><h3>Background</h3><p>Previous studies that suggest a shorter time from cervical ripening balloon placement to delivery with shorter total balloon placement time have excluded patients with prior cesarean deliveries.</p></div><div><h3>Objective</h3><p>To evaluate, in patients with a prior history of cesarean delivery undergoing cervical ripening with a double-balloon catheter, whether planned removal of device after 6 vs 12 hours would result in shorter time to vaginal delivery.</p></div><div><h3>Study Design</h3><p>A before-and-after study was performed after a practice change occurred November 2020, shortening the planned time of double-balloon catheter placement for cervical ripening from 12 to 6 hours. Data were collected via retrospective electronic chart review. Primary outcome was time from balloon placement to vaginal delivery. Secondary outcomes included rates of cesarean delivery, maternal intraamniotic infection, and uterine rupture. Kaplan–Meier curves compared median times to delivery between the groups. A Cox proportional-hazards model was used to adjust for time of balloon placement, number of previous vaginal deliveries, and co-medications used.</p></div><div><h3>Results</h3><p>From November 2018 to November 2022, 189 analyzable patients with a prior history of cesarean delivery received a double-balloon catheter for cervical ripening during their trial of labor. Patients were separated into pre- and postpolicy change groups (<em>n</em>=91 and 98, respectively). The median time to vaginal delivery for the pregroup was 28 hours (95% CI: 26, 35) and 25 hours (95% CI: 23, 29) for those in the postgroup (<em>P</em> value .052). After adjusting for dilation at time of balloon placement, number of previous vaginal deliveries, and co-medication, the estimated hazard ratio for successful vaginal delivery postpolicy change was 1.89 (95% CI: 1.27, 2.81). There were no differences in rates of secondary outcomes.</p></div><div><h3>Conclusion</h3><p>In patients with prior cesarean delivery undergoing mechanical cervical ripening with a double-balloon catheter, planned removal at 6 hours compared to 12 hours may result in higher chances of successful vaginal delivery and possibly a shorter time to delivery, without increasing rates of cesarean delivery and intraamniotic infection.</p></div>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"4 3","pages":"Article 100378"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666577824000728/pdfft?md5=1bc068d6cb1c4a8fa9c65d8a1a2e03db&pid=1-s2.0-S2666577824000728-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141953080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
We present a rare case of uterine artery pseudoaneurysm (UAP) following an emergency cesarean section, which led to severe vaginal bleeding and subcutaneous hematoma. The patient, a 40-year-old woman with no history of hemophilia or hemostasis disorders, presented with sudden profuse vaginal bleeding and multiple subcutaneous hematomas at the site of the cesarean scar ten days postoperation. Ultrasound and CT scan confirmed the presence of a pseudoaneurysm in the right uterine artery. Due to the unavailability of radiological embolization, surgical ligation of the right internal iliac artery was performed. Postoperative follow-up showed successful resolution of the pseudoaneurysm and cessation of bleeding. This case highlights the importance of considering UAP in the differential diagnosis of postpartum hemorrhage and demonstrates the efficacy of surgical intervention when embolization is not available.
{"title":"Uterine artery pseudoaneurysm presenting with subcutaneous hematoma and vaginal bleeding following cesarean delivery","authors":"Hatem Frikha, Haithem Aloui, Abir Karoui, Rami Hamami, Sana Menjli, Hassine Saber Abouda, Mohamed Badis Chanoufi","doi":"10.1016/j.xagr.2024.100382","DOIUrl":"10.1016/j.xagr.2024.100382","url":null,"abstract":"<div><p>We present a rare case of uterine artery pseudoaneurysm (UAP) following an emergency cesarean section, which led to severe vaginal bleeding and subcutaneous hematoma. The patient, a 40-year-old woman with no history of hemophilia or hemostasis disorders, presented with sudden profuse vaginal bleeding and multiple subcutaneous hematomas at the site of the cesarean scar ten days postoperation. Ultrasound and CT scan confirmed the presence of a pseudoaneurysm in the right uterine artery. Due to the unavailability of radiological embolization, surgical ligation of the right internal iliac artery was performed. Postoperative follow-up showed successful resolution of the pseudoaneurysm and cessation of bleeding. This case highlights the importance of considering UAP in the differential diagnosis of postpartum hemorrhage and demonstrates the efficacy of surgical intervention when embolization is not available.</p></div>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"4 3","pages":"Article 100382"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666577824000765/pdfft?md5=0cc4fd8382e471a4c5a3cb31cb5e1eee&pid=1-s2.0-S2666577824000765-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141842019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
National guidance conflicts regarding the use of RhD immune globulin administration <12w. Recent Society for Maternal Fetal Medicine (SMFM) guidelines suggest liberal use of this product while other guidelines, including Society of Family Planning and the World Health Organization, propose a more conservative approach. Medicine is not practiced in a vacuum, and potential harms must include not only individual but communal and public health effects. We aim to critically examine the practical implications of the new SMFM guidelines with a focus on equity and access.
{"title":"A tale of two societies: implications of conflicting Rh-immunoglobulin guidelines","authors":"Cara Heuser MD, MS , Rachel Flink-Bochacki MD, MPH , Jeffrey Sperling MD , Katharine Simmons MD, MPH , Kirsten Salmeen MD","doi":"10.1016/j.xagr.2024.100380","DOIUrl":"10.1016/j.xagr.2024.100380","url":null,"abstract":"<div><p>National guidance conflicts regarding the use of RhD immune globulin administration <12w. Recent Society for Maternal Fetal Medicine (SMFM) guidelines suggest liberal use of this product while other guidelines, including Society of Family Planning and the World Health Organization, propose a more conservative approach. Medicine is not practiced in a vacuum, and potential harms must include not only individual but communal and public health effects. We aim to critically examine the practical implications of the new SMFM guidelines with a focus on equity and access.</p></div>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"4 3","pages":"Article 100380"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666577824000741/pdfft?md5=3680cdeed5d1db06712f5e4e601f6be1&pid=1-s2.0-S2666577824000741-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141695084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Various disease prediction models have been developed, capitalizing on the wide use of electronic health records, but environmental factors that are important in the development of noncommunicable diseases are rarely included in the prediction models. Hypertensive disorders of pregnancy are leading causes of maternal morbidity and mortality and are known to cause several serious complications later in life.
Objective
This study aims to develop early hypertensive disorders of pregnancy prediction models using comprehensive environmental factors based on self-report questionnaires in early pregnancy.
Study Design
We developed machine learning and artificial intelligence models for the early prediction of hypertensive disorders of pregnancy using early pregnancy data from approximately 23,000 pregnancies in the Tohoku Medical Megabank Birth and Three Generation Cohort Study. We clarified the important features for prediction based on regression coefficients or Gini coefficients of the interpretable artificial intelligence models (i.e., logistic regression, random forest and XGBoost models) among our developed models.
Results
The performance of the early hypertensive disorders of pregnancy prediction models reached an area under the receiver operating characteristic curve of 0.93, demonstrating that the early hypertensive disorders of pregnancy prediction models developed in this study retain sufficient performance in hypertensive disorders of pregnancy prediction. Among the early prediction models, the best performing model was based on self-reported questionnaire data in early pregnancy (mean of 20.2 gestational weeks at filling) which consist of comprehensive lifestyles. The interpretation of the models reveals that both eating habits were dominantly important for prediction.
Conclusion
We have developed high-performance models for early hypertensive disorders of pregnancy prediction using large-scale cohort data from the Tohoku Medical Megabank project. Our study clearly revealed that the use of comprehensive lifestyles from self-report questionnaires led us to predict hypertensive disorders of pregnancy risk at the early stages of pregnancy, which will aid early intervention to reduce the risk of hypertensive disorders of pregnancy.
{"title":"Early prediction of hypertensive disorders of pregnancy toward preventive early intervention","authors":"Satoshi Mizuno PhD , Satoshi Nagaie PhD , Junichi Sugawara MD, PhD , Gen Tamiya PhD , Taku Obara PhD , Mami Ishikuro PhD , Shinichi Kuriyama MD, PhD , Nobuo Yaegashi MD, PhD , Hiroshi Tanaka PhD , Masayuki Yamamoto MD, PhD , Soichi Ogishima PhD","doi":"10.1016/j.xagr.2024.100383","DOIUrl":"10.1016/j.xagr.2024.100383","url":null,"abstract":"<div><h3>Background</h3><div>Various disease prediction models have been developed, capitalizing on the wide use of electronic health records, but environmental factors that are important in the development of noncommunicable diseases are rarely included in the prediction models. Hypertensive disorders of pregnancy are leading causes of maternal morbidity and mortality and are known to cause several serious complications later in life.</div></div><div><h3>Objective</h3><div>This study aims to develop early hypertensive disorders of pregnancy prediction models using comprehensive environmental factors based on self-report questionnaires in early pregnancy.</div></div><div><h3>Study Design</h3><div>We developed machine learning and artificial intelligence models for the early prediction of hypertensive disorders of pregnancy using early pregnancy data from approximately 23,000 pregnancies in the Tohoku Medical Megabank Birth and Three Generation Cohort Study. We clarified the important features for prediction based on regression coefficients or Gini coefficients of the interpretable artificial intelligence models (i.e., logistic regression, random forest and XGBoost models) among our developed models.</div></div><div><h3>Results</h3><div>The performance of the early hypertensive disorders of pregnancy prediction models reached an area under the receiver operating characteristic curve of 0.93, demonstrating that the early hypertensive disorders of pregnancy prediction models developed in this study retain sufficient performance in hypertensive disorders of pregnancy prediction. Among the early prediction models, the best performing model was based on self-reported questionnaire data in early pregnancy (mean of 20.2 gestational weeks at filling) which consist of comprehensive lifestyles. The interpretation of the models reveals that both eating habits were dominantly important for prediction.</div></div><div><h3>Conclusion</h3><div>We have developed high-performance models for early hypertensive disorders of pregnancy prediction using large-scale cohort data from the Tohoku Medical Megabank project. Our study clearly revealed that the use of comprehensive lifestyles from self-report questionnaires led us to predict hypertensive disorders of pregnancy risk at the early stages of pregnancy, which will aid early intervention to reduce the risk of hypertensive disorders of pregnancy.</div></div>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"4 4","pages":"Article 100383"},"PeriodicalIF":0.0,"publicationDate":"2024-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141848514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-06DOI: 10.1016/j.xagr.2024.100376
Leigh Senderowicz ScD , Brooke W. Bullington BA , Nathalie Sawadogo PhD , Katherine Tumlinson PhD
Background
Family planning programs are foundationally important to public health, but like any medical intervention, contraception has drawbacks in addition to its benefits. Knowledge of these drawbacks in addition to benefits is essential for informed choice. Despite a general consensus among family planning researchers and providers that contraceptive counseling should be unbiased, little quantitative research has assessed the extent of bias in contraceptive counseling, and in people's contraceptive knowledge more broadly.
Objective
To understand the extent to which women report being told more about the advantages of contraception than the disadvantages—a concept we call “asymmetry” in contraceptive counseling, at two research sites in Burkina Faso.
Methods
We use data from a cross-sectional population-based survey of 3,929 women residing in the catchment areas of the Ouagadougou (urban) and the Nouna (rural) Health and Demographic Surveillance Systems in Burkina Faso. We use descriptive statistics to explore asymmetry in knowledge of the benefits/advantages and risks/disadvantages of contraceptive use overall, as well as method-specific asymmetry among current method users regarding their counseling experience.
Findings
Results show substantial asymmetry in knowledge of advantages/benefits of contraception compared to disadvantages/risks. 86% of respondents said they could name any advantage of family planning, while half of that proportion (43%) could name any disadvantage. We find a similarly stark asymmetry in method-specific results among contraceptive users, especially for hormonal/biomedical methods. We also find substantial variation between research sites, with urban respondents much less likely to self-report complete family planning knowledge than their rural counterparts.
Conclusion
Our results suggest that family planning messaging in Burkina Faso may place an emphasis on the advantages without a commensurate focus on disadvantages. Family planning programs worldwide must ensure that people can make informed choices based on balanced, accurate information about both the benefits and the disadvantages of contraception.
{"title":"Asymmetry in contraceptive information at two sites in Burkina Faso","authors":"Leigh Senderowicz ScD , Brooke W. Bullington BA , Nathalie Sawadogo PhD , Katherine Tumlinson PhD","doi":"10.1016/j.xagr.2024.100376","DOIUrl":"10.1016/j.xagr.2024.100376","url":null,"abstract":"<div><h3>Background</h3><p>Family planning programs are foundationally important to public health, but like any medical intervention, contraception has drawbacks in addition to its benefits. Knowledge of these drawbacks in addition to benefits is essential for informed choice. Despite a general consensus among family planning researchers and providers that contraceptive counseling should be unbiased, little quantitative research has assessed the extent of bias in contraceptive counseling, and in people's contraceptive knowledge more broadly.</p></div><div><h3>Objective</h3><p>To understand the extent to which women report being told more about the advantages of contraception than the disadvantages—a concept we call “asymmetry” in contraceptive counseling, at two research sites in Burkina Faso.</p></div><div><h3>Methods</h3><p>We use data from a cross-sectional population-based survey of 3,929 women residing in the catchment areas of the Ouagadougou (urban) and the Nouna (rural) Health and Demographic Surveillance Systems in Burkina Faso. We use descriptive statistics to explore asymmetry in knowledge of the benefits/advantages and risks/disadvantages of contraceptive use overall, as well as method-specific asymmetry among current method users regarding their counseling experience.</p></div><div><h3>Findings</h3><p>Results show substantial asymmetry in knowledge of advantages/benefits of contraception compared to disadvantages/risks. 86% of respondents said they could name any advantage of family planning, while half of that proportion (43%) could name any disadvantage. We find a similarly stark asymmetry in method-specific results among contraceptive users, especially for hormonal/biomedical methods. We also find substantial variation between research sites, with urban respondents much less likely to self-report complete family planning knowledge than their rural counterparts.</p></div><div><h3>Conclusion</h3><p>Our results suggest that family planning messaging in Burkina Faso may place an emphasis on the advantages without a commensurate focus on disadvantages. Family planning programs worldwide must ensure that people can make informed choices based on balanced, accurate information about both the benefits and the disadvantages of contraception.</p></div>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"4 4","pages":"Article 100376"},"PeriodicalIF":0.0,"publicationDate":"2024-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666577824000704/pdfft?md5=5752e0268d98d7cf8c1973a1b8cd499d&pid=1-s2.0-S2666577824000704-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141703601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-29DOI: 10.1016/j.xagr.2024.100375
Bronwyn McBride PhD , Sumit Kane PhD , John O'Neil PhD , Liem T. Nguyen PhD
Despite Vietnam's overall progress on maternal health indicators, marginalized ethnic minorities in remote areas face lower access to antenatal care and higher maternal mortality rates relative to the Kinh (majority ethnic group). Last year, we conducted fieldwork for 2 qualitative research projects that aimed to address maternal health inequities among pregnant ethnic minority women in rural Northern Vietnam. Although not the focus of our research, the use of ultrasonography services at for-profit private clinics was ubiquitous in participants’ healthcare-seeking accounts. Ultrasound scans from for-profit clinics were a major component of ethnic minority women's antenatal care: many purchased 8 to 10 scans during pregnancy at $6.15 US dollars per scan, despite their limited agricultural income of $120 to $205 per month. Women were unaware of how many scans were recommended and their medically indicated scheduling, but purchased frequent scans to assuage pregnancy anxieties and access what they experienced as the highest-quality antenatal service. In tandem, for-profit ultrasonography providers offered broader opening hours, immediate results, and rich technological scans, which seemed to deliver poor families the most tangible “value” for their hard-earned money.
Previous literature documented the concerning overuse of ultrasonography among Kinh women in urban Vietnam: What are the implications of this trend extending to affect rural-dwelling ethnic minority women who face lower education, economic marginalization, and a 4-fold higher maternal mortality rate? Our findings raise concerns related to safety, financial vulnerability and provider-induced demand, and broader health policy questions regarding healthcare commodities in low-resource settings. Critically, there is no evidence of the effect of obstetrical ultrasound on reducing maternal mortality in low- and middle-income countries, and its excess use could burden available resources and detract from evidence-based services.
Our findings suggest that health system gaps are driving poor women toward frequent purchases of a single insufficient maternal health commodity: this will not improve their pregnancy outcomes or health equity for marginalized ethnic minorities. We argue that addressing this overuse of ultrasonography due to provider-induced demand requires a multipronged response that meets women's growing expectations. Our findings highlight the need for investment in health education, health promotion, and reliable high-quality public maternal healthcare for ethnic minority communities in Vietnam.
{"title":"The best healthcare (commodity) available (for purchase): provider-induced demand for obstetric ultrasonography among ethnic minority women in rural northern Vietnam","authors":"Bronwyn McBride PhD , Sumit Kane PhD , John O'Neil PhD , Liem T. Nguyen PhD","doi":"10.1016/j.xagr.2024.100375","DOIUrl":"10.1016/j.xagr.2024.100375","url":null,"abstract":"<div><p>Despite Vietnam's overall progress on maternal health indicators, marginalized ethnic minorities in remote areas face lower access to antenatal care and higher maternal mortality rates relative to the Kinh (majority ethnic group). Last year, we conducted fieldwork for 2 qualitative research projects that aimed to address maternal health inequities among pregnant ethnic minority women in rural Northern Vietnam. Although not the focus of our research, the use of ultrasonography services at for-profit private clinics was ubiquitous in participants’ healthcare-seeking accounts. Ultrasound scans from for-profit clinics were a major component of ethnic minority women's antenatal care: many purchased 8 to 10 scans during pregnancy at $6.15 US dollars per scan, despite their limited agricultural income of $120 to $205 per month. Women were unaware of how many scans were recommended and their medically indicated scheduling, but purchased frequent scans to assuage pregnancy anxieties and access what they experienced as the highest-quality antenatal service. In tandem, for-profit ultrasonography providers offered broader opening hours, immediate results, and rich technological scans, which seemed to deliver poor families the most tangible “value” for their hard-earned money.</p><p>Previous literature documented the concerning overuse of ultrasonography among Kinh women in urban Vietnam: What are the implications of this trend extending to affect rural-dwelling ethnic minority women who face lower education, economic marginalization, and a 4-fold higher maternal mortality rate? Our findings raise concerns related to safety, financial vulnerability and provider-induced demand, and broader health policy questions regarding healthcare commodities in low-resource settings. Critically, there is no evidence of the effect of obstetrical ultrasound on reducing maternal mortality in low- and middle-income countries, and its excess use could burden available resources and detract from evidence-based services.</p><p>Our findings suggest that health system gaps are driving poor women toward frequent purchases of a single insufficient maternal health commodity: this will not improve their pregnancy outcomes or health equity for marginalized ethnic minorities. We argue that addressing this overuse of ultrasonography due to provider-induced demand requires a multipronged response that meets women's growing expectations. Our findings highlight the need for investment in health education, health promotion, and reliable high-quality public maternal healthcare for ethnic minority communities in Vietnam.</p></div>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"4 3","pages":"Article 100375"},"PeriodicalIF":0.0,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666577824000698/pdfft?md5=37b9399a8fddaabc8c82d0a605831d4b&pid=1-s2.0-S2666577824000698-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141732184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-27DOI: 10.1016/j.xagr.2024.100373
José Morales-Roselló MD , Gabriela Loscalzo MD , Alicia Martínez-Varea MD , Blanca Novillo-Del Álamo , Mar Nieto-Tous
{"title":"Corrigendum to ’Primary prevention with vaginal chlorhexidine before 16 weeks reduces the incidence of preterm birth: results of the Preterm Labor Prevention Using Vaginal Antiseptics study’ [AJOG Global Reports Volume 3, Issue 4, November 2023, 100277]","authors":"José Morales-Roselló MD , Gabriela Loscalzo MD , Alicia Martínez-Varea MD , Blanca Novillo-Del Álamo , Mar Nieto-Tous","doi":"10.1016/j.xagr.2024.100373","DOIUrl":"https://doi.org/10.1016/j.xagr.2024.100373","url":null,"abstract":"","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"4 3","pages":"Article 100373"},"PeriodicalIF":0.0,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666577824000674/pdfft?md5=4972c3f47cddbebbbd71e8981d41eff4&pid=1-s2.0-S2666577824000674-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141593123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-22DOI: 10.1016/j.xagr.2024.100372
Tracy C. Bank MD, Courtney D Lynch PhD, MPH, Lynn M. Yee MD, MPH, Jasmine Johnson MD, Jiqiang Wu MSc, Rebecca McNeil PhD, Brian Mercer MD, Hyagriv Simhan MD, Uma Reddy MD, Robert M. Silver MD, Samuel Parry MD, George Saade MD, Judith Chung MD, Ronald Wapner MD, William A Grobman MD, MBA, Kartik K Venkatesh MD, PhD
{"title":"Association of neighborhood social determinants of health and hypertensive disorders of pregnancy","authors":"Tracy C. Bank MD, Courtney D Lynch PhD, MPH, Lynn M. Yee MD, MPH, Jasmine Johnson MD, Jiqiang Wu MSc, Rebecca McNeil PhD, Brian Mercer MD, Hyagriv Simhan MD, Uma Reddy MD, Robert M. Silver MD, Samuel Parry MD, George Saade MD, Judith Chung MD, Ronald Wapner MD, William A Grobman MD, MBA, Kartik K Venkatesh MD, PhD","doi":"10.1016/j.xagr.2024.100372","DOIUrl":"10.1016/j.xagr.2024.100372","url":null,"abstract":"","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"4 3","pages":"Article 100372"},"PeriodicalIF":0.0,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666577824000662/pdfft?md5=abf575177c2176d142ca2b5d6af45d4c&pid=1-s2.0-S2666577824000662-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141638707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Port-site herniation (PSH) is a rare complication observed postlaparoscopic surgery, typically associated with port sizes of 10 mm or larger, commonly occurred at umbilicus. While occurrences of extra-umbilicus with port size smaller than 10 mm are rare, we present a case detailing a lateral 7 mm PSH diagnosed on the 8th day following a total laparoscopic hysterectomy. The patient exhibited clinical symptoms indicative of partial small bowel obstruction, which became apparent on the third postoperative day. Computed tomography revealed significant small bowel dilatation and herniation through the previously employed 7 mm trocar site. Notably, this trocar site had been utilized with uterine screw. Prompt laparoscopic repair successfully addressed the herniation. The patient demonstrated satisfactory recovery and was subsequently discharged. While current practice recommends fascial incision closure for port size ≥10 mm. In light of our case, we propose considering fascial closure for small-size trocar subjected to any use of a manipulator.
{"title":"A case report and review of the literature of 7-millimeter lateral port-site herniation following total laparoscopic hysterectomy","authors":"Chartchai Srisombut MD , Nahathai Paktinun MD , Poochong Timratana MD","doi":"10.1016/j.xagr.2024.100368","DOIUrl":"10.1016/j.xagr.2024.100368","url":null,"abstract":"<div><p>Port-site herniation (PSH) is a rare complication observed postlaparoscopic surgery, typically associated with port sizes of 10 mm or larger, commonly occurred at umbilicus. While occurrences of extra-umbilicus with port size smaller than 10 mm are rare, we present a case detailing a lateral 7 mm PSH diagnosed on the 8th day following a total laparoscopic hysterectomy. The patient exhibited clinical symptoms indicative of partial small bowel obstruction, which became apparent on the third postoperative day. Computed tomography revealed significant small bowel dilatation and herniation through the previously employed 7 mm trocar site. Notably, this trocar site had been utilized with uterine screw. Prompt laparoscopic repair successfully addressed the herniation. The patient demonstrated satisfactory recovery and was subsequently discharged. While current practice recommends fascial incision closure for port size ≥10 mm. In light of our case, we propose considering fascial closure for small-size trocar subjected to any use of a manipulator.</p></div>","PeriodicalId":72141,"journal":{"name":"AJOG global reports","volume":"4 3","pages":"Article 100368"},"PeriodicalIF":0.0,"publicationDate":"2024-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666577824000625/pdfft?md5=47adc3927bb2bce12f8d54b996272116&pid=1-s2.0-S2666577824000625-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141630402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}