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Valveless Fluid Pumping via Zero-Net-Momentum Injection 通过零净动量注入的无阀流体泵送
Pub Date : 2019-03-24 DOI: 10.33697/AJUR.2019.006
Johnathan Cace
A novel mechanical method to valvelessly pump fluid has been developed using zero-net-momentum injection via a syringe and a tilted canister that function together as a periodic mass source and sink. Unlike previously discovered valveless pumping methods, this method does not require any elastic tubing and can be achieved by simple manual actuation, making it a simpler and less expensive valveless alternative. The flow rate is highly dependent on the frequency at which momentum is injected and retracted from the system. The direction of the flow can be changed by switching the location of the syringes. This pumping paradigm has potential applications in microfluidics where elastic channels are difficult to fabricate and valveless fluid actuation methods are preferred.
提出了一种新型的无阀泵送流体的机械方法,使用零净动量注射,通过注射器和倾斜罐作为周期性质量源和汇。与之前发现的无阀泵送方法不同,该方法不需要任何弹性油管,只需简单的手动驱动即可实现,使其成为一种更简单、更便宜的无阀替代方法。流量在很大程度上取决于系统注入和收回动量的频率。流动的方向可以通过切换注射器的位置来改变。这种泵送模式在难以制造弹性通道和首选无阀流体驱动方法的微流体中具有潜在的应用。
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引用次数: 0
Using Smart Glasses for Facial Recognition 使用智能眼镜进行面部识别
Pub Date : 2019-03-24 DOI: 10.33697/AJUR.2019.003
Gabriella Mayorga, Xuan Do, Vahid Heydari
Facial recognition is one of the most promising applications of smart glasses and can help many organizations become more efficient. For example, police traditionally identify criminals by manually going through pictures in a database which makes face matching a slow process. However, with the combination of facial recognition software, smart glasses, and databases, the police can quickly scan through multiple databases of faces to find a match. The police would also be able to spot criminals in crowds, identify unknown victims at crime scenes, retrieve background information on individuals, and verify if someone is a missing person. The Transportation Security Administration (TSA) can also use this combination to identify potential terror suspects or verify the identity of travelers. Lastly, academia can benefit from these tools by being able to identify individuals at events (e.g. conferences) and display relevant information about them. The goal of this project is to write an Android program that takes a photo via Google Glass, compares it with a predefined sample database held within the smartphone, and outputs information based on its analysis. The results are displayed with an accuracy acceptance level to the user both on their Android smartphone and on their Google Glass.
面部识别是智能眼镜最有前景的应用之一,可以帮助许多组织提高效率。例如,警方传统上通过手动查看数据库中的图片来识别罪犯,这使得人脸匹配过程很慢。然而,通过将面部识别软件、智能眼镜和数据库相结合,警方可以快速扫描多个人脸数据库,找到匹配的人脸。警方还将能够在人群中发现罪犯,在犯罪现场识别未知受害者,检索个人背景信息,并核实是否有人失踪。运输安全管理局(TSA)也可以使用这种组合来识别潜在的恐怖嫌疑人或核实旅行者的身份。最后,学术界可以通过在活动(如会议)中识别个人并显示有关他们的相关信息,从这些工具中受益。该项目的目标是编写一个Android程序,通过谷歌眼镜拍摄照片,将其与智能手机中预先定义的样本数据库进行比较,并根据其分析输出信息。结果在用户的Android智能手机和谷歌眼镜上都以准确度接受水平显示给用户。
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引用次数: 3
Sex Bias in Tuberculosis in the Developing World 发展中国家结核病的性别偏见
Pub Date : 2019-03-24 DOI: 10.33697/AJUR.2019.007
S. Shaw, K. Purdy
Tuberculosis (TB), the most deadly global single organism infectious disease, kills nearly twice as many men as women. Understanding the factors that drive this bias in TB mortality is an important aspect of the global effort to reduce the enormous burden of this disease in the developing world. One third of the world’s population is estimated to be infected TB, with Low and Middle Income Countries (LMIC) bearing the greatest disease burden. In LMIC sex bias in TB is influenced by sociocultural, behavioural as well as biological factors, with dynamic interactions between reporting variables, other confounding variables and physiological mechanisms, which each influence one another to produce the male-biased sex ratio observed in TB transmission, prevalence and mortality. While confounding factors are addressed in the existing global drive to tackle TB it is the biological aspects of sex bias in TB that present specific challenges for diagnosis and treatment in men and women as they potentially influence future immunological-based interventions to treat TB.
结核病是全球最致命的单体传染病,其致死人数几乎是女性的两倍。了解导致结核病死亡率出现这种偏差的因素是全球努力减轻发展中国家结核病巨大负担的一个重要方面。据估计,世界上三分之一的人口感染了结核病,中低收入国家承担着最大的疾病负担。在LMIC中,结核病的性别偏见受到社会文化、行为和生物学因素的影响,报告变量、其他混杂变量和生理机制之间存在动态相互作用,这些变量相互影响,产生了在结核病传播、流行率和死亡率中观察到的男性偏见性别比。虽然在现有的全球应对结核病运动中解决了混杂因素,但结核病性别偏见的生物学方面给男性和女性的诊断和治疗带来了具体挑战,因为它们可能会影响未来基于免疫的结核病治疗干预措施。
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引用次数: 0
Mechanotransduction in Ischemic Cardiac Tissue: A Mechanical Bidomain Approach under Plane Stress 缺血心脏组织的机械转导:平面应力下的机械双域方法
Pub Date : 2019-03-24 DOI: 10.33697/ajur.2019.001
Austin Fee, B. Roth
Mechanotransduction is the process by which biological tissue translates mechanical forces and signals, such as those produced by strains or membrane forces, into biological reactions including cell remodeling, growth, and differentiation. While some analyses assume strain (the derivative of either the intracellular or extracellular displacement) as the cause of mechanotransduction, this paper assumes that differences between the intracellular and extracellular displacements, known as membrane force, result in mechanical forces acting on integrin proteins, causing mechanotransduction. The mechanical bidomain model is a two-dimensional mathematical representation that describes this behavior. Previous analyses describe mechanotransduction using plane strain, which assumes zero displacement in the z-direction. This analysis uses plane stress, which assumes zero stress in the z-direction, to describe where mechanotransduction occurs in comparison to plane strain models. A sample of healthy tissue with a circular ischemic region with no active tension in the center is analyzed using numerical methods. Fixed and free boundary conditions are implemented. Under fixed conditions, the membrane force was largest in the ischemic border zone and zero everywhere else. However, the strain was found to be largest in the ischemic region. Under free conditions, the membrane force was largest on the vertical edges and in the ischemic border zone. The strain was found to be nearly zero in the ischemic region and ranged up to 10% throughout the tissue. In conclusion, this paper found that both plane strain and plane stress predict a membrane force in the ischemic border zone, but the distribution of individual displacements and strain vary according to each model. These results are significant in determining which model is most appropriate to use in predicting how mechanical forces affect cellular remodeling when analyzing thin monolayers of tissue.
机械转导是生物组织将机械力和信号(如菌株或膜力产生的机械力和信号)转化为包括细胞重塑、生长和分化在内的生物反应的过程。虽然一些分析假设应变(细胞内或细胞外位移的导数)是机械转导的原因,但本文假设细胞内和细胞外位移之间的差异,即膜力,导致机械力作用于整合素蛋白,导致机械转导。机械双域模型是描述这种行为的二维数学表示。先前的分析使用平面应变描述力学转导,它假设z方向上的位移为零。该分析使用平面应力,假设z方向上的应力为零,来描述与平面应变模型相比发生机械转导的位置。用数值方法分析了一个健康组织的圆形缺血区,在中心没有主动张力。实现了固定和自由边界条件。在一定条件下,膜力在缺血边界区最大,其余均为零。然而,发现该菌株在缺血区域最大。在自由条件下,膜力在垂直边缘和缺血边界区最大。该菌株在缺血区域几乎为零,在整个组织中高达10%。综上所述,本文发现平面应变和平面应力均可预测缺血边界区膜力,但各模型的个别位移和应变分布不同。这些结果在确定哪种模型最适合用于预测机械力在分析薄单层组织时如何影响细胞重塑方面具有重要意义。
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引用次数: 4
It Gets Better with Time: The Perception of Stigma Among Older Adults with Chronic Physical Illness and in Recovery from Mental Health Condition 随着时间的推移,它会变得更好:老年人慢性身体疾病和心理健康状况恢复的耻辱感
Pub Date : 2019-03-24 DOI: 10.33697/AJUR.2019.009
Angela Johnson, Kyaien O. Conner
Older adults are a vulnerable population who are more susceptible to developing mental health conditions, and the symptoms are often exacerbated by the co-occurrence of various physical health complications. Despite available evidence-based interventions, many older adults neglect to utilize mental health services, due to the stigmatization of mental health conditions. Limited research has focused on the unique experiences of older adults who have overcome the adverse effects of stigma, have sought help for their mental health condition and are currently in recovery. There are even fewer studies that have addressed perceptions of stigma among older adults in recovery from a mental health condition who are currently living with a chronic physical illness. The present study investigated the unique experiences of seeking professional mental health services and the perceptions of stigma among nine older adults living with a chronic physical illness and currently in recovery from a mental health condition utilizing semi-structured interviews. Through an in-depth thematic analysis of the data, four over-arching themes were identified: Resilience from the Stigma of a Mental Illness, Community Engagement, Cultural Barriers and Social Support System. Findings from the current study suggest that older adults who have previously experienced a mental health condition and were able to overcome the stigma of their condition, were more likely to seek professional help. Additionally, engaging in community engagement programs to help other older adults who are currently experiencing acute mental health conditions seemed to reduce perceptions of stigma and positively impacted participants self-esteem and overall outlook on life.
老年人是一个脆弱的群体,他们更容易出现心理健康状况,各种身体健康并发症的同时出现往往会加剧症状。尽管有循证干预措施,但由于对心理健康状况的污名化,许多老年人忽视了利用心理健康服务。有限的研究集中在老年人的独特经历上,他们克服了污名化的不利影响,为自己的心理健康状况寻求帮助,目前正在康复中。针对目前患有慢性身体疾病的老年人在心理健康状况康复过程中的耻辱感的研究更少。本研究利用半结构化访谈调查了九名患有慢性身体疾病并目前正在从心理健康状况中康复的老年人寻求专业心理健康服务的独特经历和耻辱感。通过对数据的深入专题分析,确定了四个总体主题:从精神疾病的耻辱中恢复过来、社区参与、文化障碍和社会支持系统。目前的研究结果表明,以前经历过心理健康状况并能够克服这种状况带来的耻辱的老年人更有可能寻求专业帮助。此外,参与社区参与计划以帮助其他目前正经历急性心理健康状况的老年人,似乎可以减少污名感,并对参与者的自尊和整体人生观产生积极影响。
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引用次数: 2
Examining Collection Biases Across Different Taxonomic Groups: Understanding How Biases Can Compare Across Herbarium Datasets 检查不同分类群的收集偏差:了解偏差如何在植物标本馆数据集中进行比较
Pub Date : 2019-03-24 DOI: 10.33697/AJUR.2019.005
Jordan Williams, Katelin D. Pearson
Specimen-based data are an invaluable resource for an increasing diversity of scientific fields, including global change biology, ecology, evolution, and genetics; however, certain analyses of these data may be limited by the non-random nature of collecting activity. Geographic, temporal, and trait-based collecting biases may consequently affect the understanding of species’ distributions, obviating the need to determine what biases exist and how they may impact further analyses. Trait-based biases were examined in herbarium specimen records of two abundant and diverse families (Asteraceae and Fabaceae) in a well-collected and digitized region (California) by comparing geographic-bias-adjusted simulations of random collections to actual collecting patterns. Collecting biases were fairly similar between families for a number of traits, such as a strong bias against collecting introduced species, while seasonal collecting biases showed a peak in activity in the Spring for both families. However, while there was only a dip in the fall for Asteraceae, Fabaceae were seriously under-collected for the majority of the year. These results demonstrate that significant collecting biases exist and may differ depending on the dataset, highlighting the importance of understanding the dataset and potentially accounting for its sampling limitations.
基于样本的数据是科学领域日益多样化的宝贵资源,包括全球变化生物学、生态学、进化论和遗传学;然而,对这些数据的某些分析可能会受到收集活动的非随机性的限制。因此,基于地理、时间和特征的收集偏差可能会影响对物种分布的理解,从而无需确定存在哪些偏差以及它们如何影响进一步的分析。在一个收集和数字化良好的地区(加利福尼亚州),通过比较随机采集的地理偏差调整模拟与实际采集模式,在两个丰富多样的科(菊科和蚕豆科)的植物标本馆标本记录中检查了基于性状的偏差。在许多特征上,不同家族之间的采集偏见相当相似,例如对采集引入物种的强烈偏见,而季节性采集偏见在春季显示出两个家族的活动高峰。然而,虽然菊科在秋季只出现了下降,但在一年的大部分时间里,菊科的采集量严重不足。这些结果表明,存在显著的收集偏差,并且可能因数据集而异,这突出了理解数据集的重要性,并可能解释其采样限制。
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引用次数: 1
Potential Consequences of Hosting an Ant-tended Treehopper, Publilia concava, for Tall Goldenrod, Solidago altissima 为高大的Goldenrod,Solidago altissima托管蚂蚁照料的树上植物Publilia concava的潜在后果
Pub Date : 2019-03-24 DOI: 10.33697//AJUR.2019.002
Luke McCartin, Nabil A. Nasseri, A. Brody
In ant-hemipteran mutualisms, ‘tending’ ants indiscriminately defend hemipterans from other arthropods, protecting mutualism-hosting plants from defoliating herbivores in some cases. Censuses of a treehopper, Publilia concava, observations of tending ants, and measurements of leaf area were conducted on tall goldenrod, Solidago altissima, over the course of a summer at a field site in central Vermont. Hosting ant-tended treehopper aggregations had no effect on leaf area or the ability for goldenrod to flower, suggesting that in the absence of an herbivore outbreak this mutualism is neither necessary nor inherently detrimental for goldenrod. These findings support the hypothesis that the net consequence of the ant-hemipteran mutualism for its host plant depends on the costs of hemipteran damage, and the benefits of ant defense from other arthropods.
在蚂蚁半翅目互惠关系中,“照料”蚂蚁不分青红皂白地保护半翅目免受其他节肢动物的伤害,在某些情况下保护共生植物免受食草动物的捕食。一个夏天,在佛蒙特州中部的一个田地里,对一株名为Publilia concava的树梢进行了普查,对照料蚂蚁进行了观察,并对高大的一枝黄花(Solidago altissima)的叶面积进行了测量。寄主蚂蚁照料的树蛙群落对叶面积或一枝黄花的开花能力没有影响,这表明在没有食草动物爆发的情况下,这种互惠互利既没有必要,也对一枝黄花本身不利。这些发现支持了这样一种假设,即蚂蚁半翅目互惠共生对宿主植物的净后果取决于半翅目损害的代价,以及蚂蚁防御其他节肢动物的好处。
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引用次数: 0
Sexual Assault Among College Students Attending a Historically Black College/University. 传统黑人学院/大学学生的性侵犯问题。
Pub Date : 2019-03-01 DOI: 10.33697/ajur.2019.004
Deshawn Collington, Markea Carter, Aliyah Tolliver, Jocelyn Turner-Musa

Sexual assault constitutes a significant public health problem on college campuses including historically Black colleges and universities (HBCU). Recent research suggests that sexual assault is increasing on college campuses. However, there are few studies examining the prevalence and risk factors for sexual assault at HBCUs. To address this gap, the current study examined the prevalence, correlates, and outcomes of sexual assault at an HBCU. Participants in the study were 264 undergraduate students from an HBCU in the mid-Atlantic region. The majority of participants were female (71%), African American (91%), and seniors (41%). After providing informed consent, participants completed a Climate Assessment survey administered by the university's Office of Diversity. Findings revealed that since starting college about 20% of students experienced sexual contact without consent. Of those sexually assaulted, 20% reported they were incapacitated or under the influence of alcohol (15%) at the time of the assault. About 17% of those assaulted experienced a physical injury and/or poor mental health outcomes (e.g., anxiety, depression, flashbacks). Participants reported not disclosing information of their assault due to embarrassment, afraid of retaliation from the perpetrator, believing it was a private matter. Close friends were more likely to be told about sexual assault. The study supports the need to address sexual assault on HBCU campuses through strong prevention and intervention programs and to address barriers to reporting.

性侵犯在包括传统黑人学院和大学(HBCU)在内的大学校园中构成了一个重大的公共卫生问题。最近的研究表明,大学校园里的性侵犯正在增加。然而,很少有研究调查hbcu性侵犯的患病率和风险因素。为了解决这一差距,目前的研究调查了HBCU性侵犯的患病率、相关性和结果。这项研究的参与者是来自大西洋中部地区一所HBCU的264名本科生。大多数参与者是女性(71%)、非洲裔美国人(91%)和老年人(41%)。在提供知情同意后,参与者完成了由大学多样性办公室管理的气候评估调查。调查结果显示,自上大学以来,约有20%的学生在未经同意的情况下发生过性接触。在遭受性侵犯的人中,20%的人报告说,他们在遭受性侵犯时丧失行为能力或受到酒精的影响(15%)。约17%的被侵犯者遭受了身体伤害和/或精神健康状况不佳(例如,焦虑、抑郁、闪回)。参与者报告说,由于尴尬,他们没有透露被侵犯的信息,害怕被侵犯者报复,认为这是私事。亲密的朋友更有可能被告知性侵犯。该研究支持通过强有力的预防和干预计划解决HBCU校园性侵犯问题,并解决举报障碍的必要性。
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引用次数: 2
Classifying Lensed Gravitational Waves in the Geometrical Optics Limit with Machine Learning 用机器学习对几何光学极限下的透镜引力波进行分类
Pub Date : 2018-10-18 DOI: 10.33697/ajur.2019.019
A. Singh, Ivan S.C. Li, O. Hannuksela, T. Li, Kyungmin Kim
Gravitational waves are theorized to be gravitationally lensed when they propagate near massive objects. Such lensing effects cause potentially detectable repeated gravitational wave patterns in ground- and space-based gravitational wave detectors. These effects are difficult to discriminate when the lens is small and the repeated patterns superpose. Traditionally, matched filtering techniques are used to identify gravitational-wave signals, but we instead aim to utilize machine learning techniques to achieve this. In this work, we implement supervised machine learning classifiers (support vector machine, random forest, multi-layer perceptron) to discriminate such lensing patterns in gravitational wave data. We train classifiers with spectrograms of both lensed and unlensed waves using both point-mass and singular isothermal sphere lens models. As the result, classifiers return F1 scores ranging from 0:852 to 0:996, with precisions from 0:917 to 0:992 and recalls ranging from 0:796 to 1:000 depending on the type of classifier and lensing model used. This supports the idea that machine learning classifiers are able to correctly determine lensed gravitational wave signals. This also suggests that in the future, machine learning classifiers may be used as a possible alternative to identify lensed gravitational wave events and to allow us to study gravitational wave sources and massive astronomical objects through further analysis.KEYWORDS: Gravitational Waves; Gravitational Lensing; Geometrical Optics; Machine Learning; Classification; Support Vector Machine; Random Tree Forest; Multi-layer Perceptron
引力波在大质量物体附近传播时,理论上是引力透镜的。这种透镜效应可能会在地面和天基引力波探测器中引起可探测的重复引力波模式。当透镜很小并且重复图案重叠时,这些效果很难区分。传统上,匹配滤波技术用于识别引力波信号,但我们的目标是利用机器学习技术来实现这一点。在这项工作中,我们实现了有监督的机器学习分类器(支持向量机、随机森林、多层感知器)来区分引力波数据中的这种透镜模式。我们使用点质量和奇异等温球透镜模型,用透镜波和非透镜波的光谱图来训练分类器。结果,分类器返回的F1分数范围从0:852到0:996,精度从0:917到0:992,召回范围从0:796到1:00,具体取决于所使用的分类器类型和透镜模型。这支持了机器学习分类器能够正确确定透镜引力波信号的观点。这也表明,在未来,机器学习分类器可能被用作识别透镜引力波事件的可能替代方案,并使我们能够通过进一步分析来研究引力波源和大质量天文物体。关键词:引力波;引力透镜;几何光学;机器学习;分类支持向量机;随机森林;多层感知器
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引用次数: 3
Volume 15, Issue 2 第15卷第2期
Pub Date : 2018-09-26 DOI: 10.33697/ajur.2018.013
R. Bieder
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引用次数: 13
期刊
American journal of undergraduate research
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