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Cost, Quality, and Access of Healthcare in Piura, Peru 秘鲁皮乌拉医疗保健的成本、质量和可及性
Pub Date : 2019-09-30 DOI: 10.33697/ajur.2019.020
J. Griffin, E. Osterbur
The aim of the study is to investigate the patient perceptions on the cost, quality, and access of health care services in Piura, Peru. Although one of the largest cities in Peru, Piura has one of the lowest densities of health care workers in the country which greatly impacts the population’s ability to receive medical treatment. Lack of financial resources and health literacy, among other health disparities exist. Modeled after CAHPS Health Plan Adult Commercial Survey 5.0 and the Patient Satisfaction Survey, a forty-four question English and Spanish survey was created with questions to study healthcare variables. As a correlational study with convenience sampling, the survey was administered to both patients and medical providers in eight city health centers. Over a period of twelve days, 107 surveys were collected. After eliminating subjects who did not meet the study criteria, 92 patients and 13 medical providers were included in the study. Findings from medical providers are not reported because of the small sample size. The results of this study suggests that 32% of subjects do not have health insurance, 24% of subjects rated their healthcare received as average, 18% of participants rated their healthcare as the best possible on a scale of zero to ten, and 29% of subjects had to wait an average of seven days for access to healthcare services when care is urgent. The results of this analysis can be used to better understand the Peruvian healthcare system and educate the Piura community and the Parish Santísimo Sacramento as they continue to improve and expand their health care services.KEYWORDS: Cost; Quality; Access; Healthcare; Piura; Peru; Satisfaction; Parroquia Santísimo Sacramento; EsSalud; SIS; MINSA
本研究的目的是调查秘鲁皮乌拉市患者对医疗保健服务的成本、质量和可及性的看法。皮乌拉虽然是秘鲁最大的城市之一,但却是全国卫生保健工作者密度最低的城市之一,这极大地影响了人口接受医疗的能力。缺乏财政资源和卫生知识普及,以及存在其他卫生差距。以CAHPS健康计划成人商业调查5.0和患者满意度调查为模型,创建了一个包含44个问题的英语和西班牙语调查,其中包含研究医疗变量的问题。作为一项方便抽样的相关性研究,该调查对8个城市卫生中心的患者和医疗提供者进行了调查。在12天的时间里,收集了107份调查。在剔除不符合研究标准的受试者后,92名患者和13名医疗服务提供者被纳入研究。由于样本量小,没有报告医疗提供者的调查结果。这项研究的结果表明,32%的受试者没有医疗保险,24%的受试者认为他们获得的医疗保健为平均水平,18%的受试者认为他们的医疗保健在0到10的范围内是最好的,29%的受试者在紧急护理时必须平均等待7天才能获得医疗保健服务。这项分析的结果可以用来更好地了解秘鲁的医疗保健系统,并教育Piura社区和教区Santísimo萨克拉门托,因为他们继续改善和扩大他们的医疗保健服务。关键词:成本;质量;访问;医疗保健;皮乌拉;秘鲁;满意度;帕罗基亚Santísimo萨克拉门托;EsSalud;姐姐;MINSA
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引用次数: 1
The Association of TAS1R2 to Dental and Cardiovascular Health TAS1R2与牙齿和心血管健康的关系
Pub Date : 2019-09-30 DOI: 10.33697/ajur.2019.022
Joseph Keryakos, A. M. V. Oosbree, A. Kiesow
Despite brushing and/or flossing their teeth twice daily, many people are still susceptible to dental cavities and tooth decay. This research investigates the genetic and cardiovascular health behind this phenomenon. Two gene variants related to taste pathways, taste 1 receptor member 2 (TAS1R2) and taste 2 receptor member 38 (TAS2R38), were tested on the DNA of 20 students at Northern State University (10 males and 10 females). In concert with genetic screening, tooth impressions were taken of the participants’ upper and lower jaws along with salivary pH, heart rates, and blood pressures. Participants’ cavities and fillings were counted and their gums examined for inflammation. Results showed that seven out of 10 males and two out of 10 females had the gene variant (TAS1R2). Students with this gene variant had an average salivary pH of 5.22—significantly lower than the salivary pH for the other non-carrier students (p < 0.05). These students also had smaller-sized tooth enamel, with none showing a size greater than one millimeter (x̄ = 0.84 millimeters). Students not expressing the gene variant had fewer cavities than those expressing the TAS1R2 gene variant (i.e., one of the regions amplified). Four of the males and both of the females that carried the gene variant also showed signs of swollen gums, possibly contributing to heart disease in the future. Blood pressures and heart rates for the carriers were statistically significant (p < 0.05), showing higher pressures and faster rates compared to non-carriers; meanwhile, all of the non-carriers had normal pressures and rates. Further, body mass index was lower among individuals without the gene variant. The results this limited study indicate that the TAS1R2 gene variant may play a role in cavity development and impact (or indicate poor) cardiovascular health, highlighting the importance of understanding the role of gene variants with regard to risk of tooth decay and gum and heart disease. KEYWORDS: Dental cavities; Tooth decay; Gum and heart disease; Taste pathway gene; Gene variant; Blood pressure; Heart rate; Salivary pH; Tooth enamel
尽管每天刷牙和/或用牙线洁牙两次,但许多人仍然容易患蛀牙和蛀牙。这项研究调查了这一现象背后的遗传和心血管健康。在北方州立大学20名学生(10名男性和10名女性)的DNA上测试了两种与味觉途径相关的基因变体,味觉1受体成员2(TAS1R2)和味觉2受体成员38(TAS2R38)。在进行基因筛查的同时,对参与者的上下颚以及唾液pH值、心率和血压进行了牙齿印模检查。对参与者的蛀牙和填充物进行计数,并检查他们的牙龈是否发炎。结果显示,十分之七的男性和十分之二的女性具有该基因变体(TAS1R2)。具有该基因变体的学生的平均唾液pH值为5.22,显著低于其他非携带者学生的唾液pH值(p<0.05)。这些学生的牙釉质尺寸也较小,没有一个牙釉质尺寸大于1毫米(x̄=0.84毫米)。未表达该基因变体的学生比表达TAS1R2基因变体(即扩增的区域之一)的学生有更少的空腔。携带该基因变体的四名男性和两名女性也表现出牙龈肿胀的迹象,这可能会导致未来的心脏病。携带者的血压和心率具有统计学意义(p<0.05),与非携带者相比,显示出更高的血压和更快的心率;同时,所有非携带者都有正常的压力和速率。此外,在没有该基因变体的个体中,体重指数较低。这项有限的研究结果表明,TAS1R2基因变体可能在口腔发育中发挥作用,并影响(或表明)心血管健康,这突出了了解基因变体在蛀牙、牙龈和心脏病风险方面的作用的重要性。关键词:口腔;蛀牙牙龈和心脏病;味觉通路基因;基因变异;血压心率;唾液pH值;牙釉质
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引用次数: 0
Body Image and Self-Esteem in Female College Students of Healthy Weight and Excess Weight: The Mediating Role of Weight Stigma 健康体重与超重女大学生的身体形象与自尊:体重污名的中介作用
Pub Date : 2019-09-30 DOI: 10.33697/ajur.2019.025
Carli A. Smith, J. Becnel, A. Williams
Emerging adulthood is an important transition in which the development of lifelong behaviors emerge. Recent research suggests that women in college are particularly vulnerable to poor body image and low self-esteem. This is also a time of possible weight gain as individuals learn to eat and exercise on their own. These are important as body mass index (BMI) influences how women feel about themselves and how others view them. Thus, the purpose of the present study was to examine the associations between body image, self-esteem, and weight stigma among female college students of healthy weight and excess weight. Participants (n=124; 83% White) were recruited to take a short survey administered online through Facebook advertisements and snowball sampling. Results reveled poorer body image and more experiences with weight stigma among individuals with excess weight. Additionally, weight stigma fully mediated the relationship between BMI and self-esteem as well as BMI and body image. Results were consistent with previous research noting the stigma and stereotypes associated with excess weight. Future work should examine these relationships in more diverse groups to identify those at greatest risk for negative self-concept for intervention. KEYWORDS: Weight; Weight Stigma; Self-Esteem; Body Image; College Students; Women
初成期是一个重要的过渡时期,在此期间,终身行为的发展开始显现。最近的研究表明,大学女生特别容易受到身体形象不佳和自卑的影响。这也是一个可能增加体重的时期,因为人们学会了自己吃和锻炼。这些都很重要,因为身体质量指数(BMI)会影响女性对自己的感觉以及别人对她们的看法。因此,本研究的目的是探讨健康体重和超重女大学生的身体形象、自尊和体重耻辱感之间的关系。参与者(n = 124;(83%是白人),通过Facebook广告和滚雪球抽样的方式进行了一项简短的在线调查。结果显示,超重个体的身体形象较差,并且有更多的体重耻辱感。此外,体重耻辱感完全介导了BMI与自尊、BMI与身体形象之间的关系。结果与之前的研究一致,即超重与耻辱和刻板印象有关。未来的工作应该在更多不同的群体中研究这些关系,以确定那些具有最大风险的负面自我概念进行干预。关键词:重量;重污名;自尊;身体形象;大学生;女性
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引用次数: 1
Diol Mediated Tautomerization of Glycine: a DFT Study 二醇介导的甘氨酸互变异构反应的DFT研究
Pub Date : 2019-06-23 DOI: 10.33697/AJUR.2019.014
Francis Suh, Vanessa Rivera, R. Parra
The tautomerization of glycine via a triple proton transfer was investigated both in the gas phase and in aqueous solution using the B3LYP/6-31+G(d,p) level of theory. Fully optimized complexes of the neutral and zwitterion forms of glycine with 1,3-propanediol were used for the reactant and product forms, respectively. The hydroxyl groups in the diol are conveniently oriented for glycine tautomerization through a concerted triple proton transfer facilitated by a network of three hydrogen bonds: N-H…O-H…O-H…O=C. The activation energy for the zwitterion à neutral process increases in solution. Also, the diol-glycine complex favors the neutral over the zwitterion form in a vacuum, but the opposite is true in solution. For comparative purposes, the tautomerization of glycine via a three-proton transfer mediated by two molecules of water was also examined. The results are qualitatively similar, albeit with activation energies that are smaller to those found in the corresponding diol-mediated tautomerization.KEYWORDS: Glycine; zwitterion, diol-mediated tautomerization; water-mediated tautomerization
利用B3LYP/6-31+G(d,p)理论水平,在气相和水溶液中研究了甘氨酸通过三重质子转移的互变异构化。完全优化的中性和两性离子形式的甘氨酸与1,3-丙二醇的配合物分别用于反应物和产物形式。二醇中的羟基通过三个氢键网络促进的协同三重质子转移方便地定向用于甘氨酸互变异构化:N-H…O-H…O-H.…O=C。两性离子中性过程的活化能在溶液中增加。此外,在真空中,二醇-甘氨酸络合物倾向于中性形式,而不是两性离子形式,但在溶液中则相反。为了进行比较,还研究了甘氨酸通过两分子水介导的三质子转移的互变异构作用。结果在性质上是相似的,尽管活化能小于在相应的二醇介导的互变异构化中发现的活化能。关键词:甘氨酸;两性离子、二醇介导的互变异构化;水介导的互变异构化
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引用次数: 0
Should high-top or low-top cleats be used when playing baseball 打棒球时应该使用高帮还是低帮防滑鞋
Pub Date : 2019-06-23 DOI: 10.33697/AJUR.2019.011
Margo Wohlfeil, Cole Neary, Mitchell Klocke, J. Mills, Rich Calvert, D. Senchina
There is a shortage of knowledge about how baseball cleat design may impact athletes. The purpose of this experiment was to determine if the height of the baseball cleat affected performance, perception of the cleat, and ankle range-of-motion. Thirteen subjects participated in the study, and each subject performed three drills (base-running, 5:10:5 "pro agility," and hitting) in both high-top and low-top baseball cleats. Performance time was measured for the first two drills. Perception of comfort, heaviness, shoe climate (heat), stability, and traction were measured for all three drills using 10-cm visual analog scales (VAS). Ankle range-of-motion (dorsiflexion, plantarflexion, eversion, and inversion) was measured using goniometry in both cleats, plus socks-only as baseline control. Shoe height did not significantly affect completion time in either the base-running drill (6.1±0.1 sec. in high-top vs. 6.1±0.1 sec. in low-top) or pro-agility drill (4.8±0.1 sec. in high-top vs. 4.6±0.1 sec. in low-top). There were significant differences in perception of heat (6.4 in high-top vs. 4.6 in low-top; p<.001), stability (6.9 in high-top vs. 5.1 in low-top; p=.001), and heaviness (6.0 in high-top vs. 4.1 in low-top; p<.001), but not in perception of comfort (6.1±2.0 in high-top vs. 6.6±1.5 in low top) or traction (7.3±2.0 in high-top vs. 7.4±1.5 in low-top). There were significant differences between high-top and low-top cleats in plantarflexion (42.5° in high-top vs. 47.5° in low-top; p=.033), eversion (7.9° in high-top vs. 11.3° in low-top; p=.003), and inversion (12.8° in high-top vs. 16.6° in low-top; p=.044), but not dorsiflexion (8.2° in high-top vs. 10.9°). For baseball players concerned about excessive ankle movements during play, these results suggest that using a high-top baseball cleat might reduce ankle range-of-motion without impairing performance or feeling burdensome.KEYWORDS: Baseball; Cleats; High-Top; Low-Top; Perception; Performance; Range-of-Motion; Shoes
关于棒球球网设计如何影响运动员的知识缺乏。这个实验的目的是确定棒球清净的高度是否影响表现,清净的感知和脚踝的活动范围。13名受试者参加了这项研究,每个受试者都穿着高帮和低帮棒球鞋进行了三次训练(跑垒,5:10:5“专业敏捷性”和击球)。测量了前两次演练的性能时间。使用10厘米视觉模拟量表(VAS)测量所有三种钻头的舒适度、重量、鞋子气候(热)、稳定性和牵引力。踝关节活动范围(背屈、跖屈、外翻和内翻)采用角度测量法测量,同时只穿袜子作为基线对照。鞋高对基础跑步训练(高帮6.1±0.1秒vs低帮6.1±0.1秒)或敏捷训练(高帮4.8±0.1秒vs低帮4.6±0.1秒)的完成时间没有显著影响。在热感知方面存在显著差异(高帮6.4 vs低帮4.6;P < 0.001),稳定性(高帮组6.9 vs低帮组5.1;P =.001)和重量(高帮6.0 vs低帮4.1;P < 0.001),但舒适感(高帮组6.1±2.0比低帮组6.6±1.5)或牵引力(高帮组7.3±2.0比低帮组7.4±1.5)方面没有差异。高帮和低帮夹板在跖屈曲方面存在显著差异(高帮42.5°vs低帮47.5°);P = 0.033),外翻(高帮7.9°vs低帮11.3°;P = 0.003),倒置(高顶12.8°vs低顶16.6°;P = 0.044),但不存在背屈(高帮鞋8.2°vs. 10.9°)。对于在比赛中担心踝关节过度运动的棒球运动员来说,这些结果表明,使用高帮棒球球鞋可能会减少踝关节的活动范围,而不会影响比赛表现或感到负担。关键词:棒球;楔子;高帮;Low-Top;知觉;性能;的活动范围;鞋子
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引用次数: 0
Investigation of Atmospheric Aerosol Size Distributions from Ground-Based Solar Spectrometer Measurements Synthesized with Satellite Data 基于卫星数据合成的地面太阳光谱仪测量的大气气溶胶粒径分布研究
Pub Date : 2019-06-23 DOI: 10.33697/AJUR.2019.013
Dane Kuhr, A. Whitten
Data collected by a ground-based solar spectrometer at Collegeville, MN, was used to generate Aerosol Optical Depths (AODs) throughout the 2017 calendar year. The AOD data was then visualized at 13 selected wavelengths throughout the year and analyzed in comparison to satellite imagery, upper air charts and backwards trajectories of air masses moving towards Central Minnesota in order to determine key dates of interest that correspond to times before (20170615), during (20170729), and at the conclusion of (20170914) forest fires that burned in British Columbia (BC) during the summer of 2017. The data from these specific days were analyzed further by inputting the maximum and minimum AODs for each day into a Parameter Based Particle Swarm Optimization (PBPSO) algorithm in order to generate bimodal lognormal particle size distributions. The bimodal distributions were chosen because they carry more information about the aerosol loads across the entire spectrum of particle radii. The resulting distributions show an increase in number density and decrease in median radius in the Aitken mode during the BC forest fires and a relatively constant (within uncertainty) number density of accumulation mode particles at daily maximum AODs. Comparing the resulting bimodal lognormal distribution for daily minimum AODs (where evaporation and other diurnal effects are at a minimum) shows an increased number density of Aitken mode particles by two orders of magnitude from pre- to post-forest fires. This measured increase in the number density of smaller radii particles due to forest fires illustrates the PBPSO’s capability of distinguishing variations in atmospheric aerosol particle number size distributions in the Aitken mode based on data collected by the Kipp-Zonen PGS-100 solar spectrometer.KEYWORDS: Atmospheric Aerosol; Particle Swarm Optimization; Aerosol Optical Depth; Solar Spectrometer; Size Distributions; Forest Fire; Satellite Imagery; Upper Air Charts; Backward Trajectory
MN Collegeville的地面太阳光谱仪收集的数据用于生成2017日历年的气溶胶光学深度(AOD)。然后,在全年13个选定波长下对AOD数据进行可视化,并与卫星图像、高空图和向明尼苏达州中部移动的气团的向后轨迹进行比较分析,以确定与之前(20170615)、期间(20170729)、,以及在2017年夏天不列颠哥伦比亚省(BC)发生的(20170914)森林大火结束时。通过将每天的最大和最小AOD输入到基于参数的粒子群优化(PBPSO)算法中,进一步分析这些特定日子的数据,以生成双峰对数正态粒度分布。之所以选择双峰分布,是因为它们在整个粒子半径谱中携带了更多关于气溶胶载荷的信息。由此产生的分布显示,在不列颠哥伦比亚省森林火灾期间,艾特肯模式的数量密度增加,中值半径减小,并且在日最大AOD下,积累模式粒子的数量密度相对恒定(在不确定性范围内)。比较由此产生的日最小AOD的双峰对数正态分布(其中蒸发和其他日效应最小)表明,从森林火灾前到火灾后,艾特肯模式粒子的数量密度增加了两个数量级。森林火灾导致的较小半径颗粒数量密度的测量增加表明,基于Kipp-Zonen PGS-100太阳能光谱仪收集的数据,PBPSO能够区分艾特肯模式下大气气溶胶颗粒数量大小分布的变化。关键词:大气气溶胶;粒子群优化;气溶胶光学深度;太阳光谱仪;规模分布;森林火灾;卫星图像;高空图表;向后轨迹
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引用次数: 0
Assessing the Use of Cooking Demonstrations on Healthy Eating Barriers in City Bus Riders 评估烹饪示范在城市公交车乘客健康饮食障碍中的应用
Pub Date : 2019-06-23 DOI: 10.33697/AJUR.2019.017
Julianne Evans, D. C. Castellanos
People living in food-insecure households may experience access-related barriers to preparing and consuming fresh produce, such as high cost and limited local availability. Nutrition interventions that incorporate improved access play a decisive role in overcoming these barriers. The urban bus hub fresh produce market was developed to address food insecurity in Dayton, Ohio. Over four months, dietetic students from a four-year, private, mid-western university provided cooking demonstrations and recipe distribution nutrition interventions at the market. We used a quasi-experimental study design to determine the effectiveness of the cooking demonstration and recipe distribution intervention on access-related barriers at the urban bus hub fresh produce market. A ten-item quantitative questionnaire, on a Likert-type scale from 1-10, with 10 as a more favorable response, and four open-ended questions were administered once to each consented participant (N=33) to examine the recipe effectives and explore the access-related barriers. T-tests were used to examine barriers from the questionnaire and determine differences between participants who made the recipe and participants who did not make the recipe. Results of the t-test indicate no significant difference between those who made the recipe and those who did not make the recipe (p>0.05). Mean scores for affordability, acceptability, accommodation, availability, and accessibility on the then ten-item questionnaire were 7.83, 8.44, 9.19, 9.38, and 8.44, respectively. Thematic analysis results were used to examine the barriers from the open-ended questions further and revealed that affordability and time barriers were present in the priority population. Lack of money, job loss, and unemployment were identified as contributing to affordability barriers and transportation and time to shop, prepare, or cook produce, and to find mealtimes were identified as contributing to time barriers. Nutrition professionals should continue developing appropriate interventions for affordability and time barriers in convenient locations for participants to encourage fruit and vegetable consumption and to establish evidence-based practices.KEYWORDS: Cooking demonstrations; food insecurity; produce consumption barriers; nutrition intervention; food stand; recipe distribution; bus hub
生活在粮食不安全家庭的人们在准备和消费新鲜农产品时可能会遇到与获取相关的障碍,例如成本高和当地供应有限。营养干预措施包括改善获取途径,在克服这些障碍方面发挥着决定性作用。城市公交枢纽新鲜农产品市场是为了解决俄亥俄州代顿的粮食不安全问题而开发的。在四个多月的时间里,来自中西部一所四年制私立大学的营养学学生在市场上提供了烹饪示范和食谱分发营养干预。我们使用准实验研究设计来确定烹饪示范和配方分配干预对城市公交枢纽新鲜农产品市场准入相关障碍的有效性。一份10项定量问卷,采用Likert型量表,从1-10分,10分为更有利的回答,对每个同意的参与者(N=33)进行一次四个开放式问题,以检查配方的有效性并探索与获取相关的障碍。T检验用于检查问卷中的障碍,并确定制定配方的参与者和未制定配方的与会者之间的差异。t检验结果表明,制作配方的人和未制作配方的人们之间没有显著差异(p>0.05)。在当时的十项问卷中,负担能力、可接受性、住宿、可用性和可及性的平均得分分别为7.83、8.44、9.19、9.38和8.44。专题分析结果用于进一步审查开放式问题的障碍,并表明优先人群存在负担能力和时间障碍。缺乏资金、失业和失业被认为是造成负担能力障碍的原因,而购物、准备或烹饪农产品的交通和时间以及寻找用餐时间被认为是导致时间障碍的原因。营养专业人员应继续在方便的地点为参与者制定适当的干预措施,以解决负担能力和时间障碍,鼓励他们食用水果和蔬菜,并建立循证实践。关键词:烹饪示范;粮食不安全;生产消费壁垒;营养干预;食品摊;配方分配;公共汽车枢纽
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引用次数: 0
Psychological Constructs as Predictors of Strength Gains in a Strength Training Course 心理构念作为力量训练课程力量增益的预测因子
Pub Date : 2019-06-23 DOI: 10.33697/AJUR.2019.015
Kathrine Hadley, J. Morrissey
Strength training has many benefits, both affective and physical health-related. However, little research has been done on the psychological constructs that play an important role in exercise adherence, maintenance, and outcomes regarding strength training specifically. The purpose of this study was to examine self-efficacy (SE), perceived competence (PC), and outcome expectancy (OE), several of the key psychological constructs, as predictors of strength gains in a strength training course. It was hypothesized that the changes in participants’ measures of SE, PC, and OE from baseline to post-training would predict participants’ actual strength gains, but not the levels of SE, PC, and OE at baseline and post-training independently. Participants (n=20; 50% 20-21 years old, 40% 22-24 years old, 10% 25 years or older; 60% female, 40% male; 45% Caucasian, 30% Hispanic/Latino, 20% multiracial, 5% Asian/Pacific Islander) in a 15-week strength training technique (STT) course completed a battery of psychological questionnaires assessing SE, PC, and OE in addition to fitness tests consisting of a vertical jump test, an estimated one repetition maximum bench press and a back squat at baseline, mid- and post-training. One-way repeated measures ANOVA was used to examine differences in SE, PC, and OE at baseline, mid-, and post-training. Spearman correlation and multiple regression analyses were used to determine the predictive specificity of baseline, mid-, post-training levels, and changes in SE, PC, and OE on strength gains. ANOVA results show a significant time effect, as there was a significant increase in all three variables over time, suggesting that course participation increased students’ SE, OE, and PC about strength training. Baseline scores, post-training scores, and changes in SE, PC, and OE were not significant predictors of changes in strength or power scores. These results suggest that while an instructor-led STT course may increase SE, OE, and PC for individuals with varying strength training experience and positively influence college students’ well-being, these psychological constructs may not predict strength gains. Future research should examine possible predictive factors for strength training outcomes in larger, more heterogeneous populations.KEYWORDS: StrengthTraining; Self-Efficacy; Perceived Competence; Outcome Expectancy; Psychological Constructs; Kinesiology; Strength and Conditioning; Resistance Training
力量训练有很多好处,无论是情感上的还是身体上的。然而,关于心理结构在运动坚持、维持和力量训练结果中发挥重要作用的研究很少。本研究的目的是检验自我效能(SE),感知能力(PC)和结果预期(OE),几个关键的心理构念,作为力量训练课程中力量增益的预测因子。假设参与者的SE、PC和OE测量值从基线到训练后的变化可以独立预测参与者的实际力量增益,但不能独立预测基线和训练后的SE、PC和OE水平。参与者(n = 20;20-21岁占50%,22-24岁占40%,25岁及以上占10%;女性占60%,男性占40%;45%的白种人,30%的西班牙裔/拉丁裔,20%的多种族,5%的亚洲/太平洋岛民在15周的力量训练技术(STT)课程中完成了一系列评估SE, PC和OE的心理问卷,此外还有体能测试,包括垂直跳跃测试,估计重复一次最大卧推和在基线,训练中期和训练后的后蹲。采用单因素重复测量方差分析检查SE、PC和OE在基线、训练中和训练后的差异。使用Spearman相关和多元回归分析来确定基线、训练中期、训练后水平以及SE、PC和OE变化对力量增加的预测特异性。方差分析结果显示了显著的时间效应,因为所有三个变量都随着时间的推移而显著增加,这表明课程参与增加了学生对力量训练的SE, OE和PC。基线评分、训练后评分以及SE、PC和OE的变化不是力量或力量评分变化的显著预测因子。这些结果表明,尽管教师主导的STT课程可以提高具有不同力量训练经验的个体的SE、OE和PC,并对大学生的幸福感产生积极影响,但这些心理构念可能无法预测力量增益。未来的研究应该在更大、更异质的人群中检验力量训练结果的可能预测因素。关键词:StrengthTraining;自我效能感;感知能力;预期结果;心理结构;运动机能学;力量和调节;阻力训练
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引用次数: 1
Modeling Networks of Evolving Populations 进化种群的网络建模
Pub Date : 2019-06-23 DOI: 10.33697/AJUR.2019.016
S. Elliott
The goal of this research is to devise a method of differential equation based modeling of evolution that can scale up to capture complex dynamics by enabling the inclusion of many—potentially thousands—of biological characteristics. Towards that goal, a mathematical model for evolution based on the well-established Fisher-Eigen process is built with a unique and efficient structure. The Fisher-Eigen partial differential equation (PDE) describes the evolution of a probability density function representing the distribution of a population over a phenotype space. This equation depends on the choice of a fitness function representing the likelihood of reproductive success at each point in the phenotype space. The Fisher-Eigen model has been studied analytically for simple fitness functions, but in general no analytic solution is known. Furthermore, with traditional numerical methods, the equation becomes exponentially complex to simulate as the dimensionality of the problem expands to include more phenotypes. For this research, a network model is synthesized and a set of ordinary differential equations (ODEs) is extracted based on the Fisher-Eigen PDE to describe the dynamic behavior of the system. It is demonstrated that, when juxtaposed with full numerical PDE simulations, this ODE model finds well-matched transient and precise equilibrium solutions. This prototype method makes modeling of high-dimensional data possible, allowing researchers to examine and even predict complex dynamic behavior based on a snapshot of a population.KEYWORDS: Evolutionary Modeling; Mathematical Biology; Network Dynamics; Ordinary Differential Equations; Partial Differential Equations; Fisher-Eigen model; Phenotype; Fitness Function
这项研究的目标是设计一种基于微分方程的进化建模方法,该方法可以通过包含许多——可能是数千个——生物特征来放大以捕捉复杂的动力学。为了实现这一目标,建立了一个基于公认的Fisher特征过程的进化数学模型,该模型具有独特而有效的结构。Fisher特征偏微分方程(PDE)描述了概率密度函数的演化,该函数表示种群在表型空间上的分布。该方程取决于适应度函数的选择,该适应度函数表示表型空间中每个点的繁殖成功的可能性。对于简单的适应度函数,已经对Fisher特征模型进行了解析研究,但通常还不知道解析解。此外,使用传统的数值方法,随着问题的维度扩展到包括更多表型,方程的模拟变得指数复杂。在本研究中,综合了一个网络模型,并基于Fisher特征PDE提取了一组常微分方程(ODE)来描述系统的动态行为。结果表明,当与全数值PDE模拟并置时,该ODE模型可以找到匹配良好的瞬态和精确的平衡解。这种原型方法使高维数据的建模成为可能,使研究人员能够根据人群的快照来检查甚至预测复杂的动态行为。关键词:进化建模;数学生物学;网络动力学;常微分方程;偏微分方程;Fisher-Eigen模型;表型;健身功能
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引用次数: 0
Transcription of nanos-1 in Zebrafish Embryos is not Affected by Bisphenol A: Evaluated Using Quantitative Real-Time PCR 纳米-1在斑马鱼胚胎中的转录不受双酚A的影响:用定量实时PCR评估
Pub Date : 2019-06-23 DOI: 10.33697/AJUR.2019.012
B. Babich, George Roba, S. Safura, K. Callahan, Edward A. Freeman
The presence of primordial germ cells (PGCs) is crucial for proper gonad formation in zebrafish (Danio rerio). The many aspects of PGC migration that allow these cells to reach the proper location at the gonadal ridge include receptors, ligands, germ plasm components, and internal maintenance of PGCs. Any one of these factors could be affected by endocrine-disrupting chemicals (EDCs), which have been shown to alter the directed migration of these cells during early embryonic development. Based on recent research wherein the EDC bisphenol A (BPA) inhibited normal PGC migration, we have used the same dose of BPA to determine the impact of BPA on a gene central to proper germ cell migration. Zebrafish embryos were exposed to BPA, and the levels of the target gene nanos-1 were analyzed using quantitative real-time PCR (q-PCR). The target gene nanos-1 is a critically important germplasm component that allows for survival and proper migration of PGCs. The q-PCR results showed that BPA did not affect the transcription level of nanos-1 in zebrafish embryos.KEYWORDS: Zebrafish; Zebrafish Embryos; nanos-1; Primordial Germ Cells; PGC Migration; Gonad Development; Endocrine-Disrupting Chemicals; Bisphenol A; Sex Determination
原始生殖细胞(PGCs)的存在对斑马鱼性腺的正常形成至关重要。PGC迁移的许多方面使这些细胞能够到达性腺嵴的适当位置,包括受体、配体、种质成分和PGC的内部维持。这些因素中的任何一个都可能受到内分泌干扰物(EDCs)的影响,这些化学物质已被证明在胚胎早期发育过程中会改变这些细胞的定向迁移。基于最近的研究,其中EDC双酚A(BPA)抑制了PGC的正常迁移,我们使用了相同剂量的BPA来确定BPA对生殖细胞正常迁移的核心基因的影响。将斑马鱼胚胎暴露于BPA中,并使用定量实时PCR(q-PCR)分析靶基因nanos-1的水平。靶基因纳米-1是一种极其重要的种质成分,可以使PGCs存活和适当迁移。q-PCR结果表明,BPA对斑马鱼胚胎中nanos-1的转录水平没有影响。关键词:斑马鱼;斑马鱼胚胎;纳米-1;原始生殖细胞;PGC迁移;性腺发育;内分泌破坏性化学物质;双酚A;性别决定
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引用次数: 1
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American journal of undergraduate research
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