South Asian American (SA) women are diagnosed with more aggressive breast cancer than non-Hispanic White (NHW) women. Understanding the factors associated with the types of surgery received by these women sheds light on disease management in these culturally distinct populations. We used data on age at diagnosis, stage, grade, estrogen and progesterone receptors, and surgery from 4,590 SA and 429,030 NHW breast cancer cases in the Surveillance, Epidemiology and End Results (SEER) program. We used logistic regression with surgery as the binary outcome (subcutaneous, total, or radical mastectomy (STRM) versus partial mastectomy, no, unknown or other (PNUM)) and included additive effects of all the variables and interactions of age, stage, grade, and estrogen and progesterone receptors with race/ethnicity. Type I error of 5% was used to assess statistical significance of the effects. SA were significantly more likely than NHW cases to receive STRM relative to PNUM surgery among women diagnosed at or after age 50 years and having localized stage disease (Odds Ratio (OR) = 1.27, 95% Confidence Interval (CI) = 1.06 - 1.52). Further, SA were significantly less likely than NHW cases to receive STRM relative to PNUM surgery among those diagnosed before age 50 years and having regional or distant stage disease (OR = 0.75, 95% CI = 0.59 - 0.95 for age at diagnosis < 40 years; OR = 0.77, 95% CI = 0.62 - 0.95 for age at diagnosis 40-49 years). The type of surgery received by SA and NHW women differ according to age at diagnosis and disease stage.
{"title":"Factors Associated with Surgery Among South Asian American and Non-Hispanic White Women with Breast Cancer.","authors":"Lydia Lo, Jaya M Satagopan","doi":"10.33697/ajur.2021.048","DOIUrl":"https://doi.org/10.33697/ajur.2021.048","url":null,"abstract":"<p><p>South Asian American (SA) women are diagnosed with more aggressive breast cancer than non-Hispanic White (NHW) women. Understanding the factors associated with the types of surgery received by these women sheds light on disease management in these culturally distinct populations. We used data on age at diagnosis, stage, grade, estrogen and progesterone receptors, and surgery from 4,590 SA and 429,030 NHW breast cancer cases in the Surveillance, Epidemiology and End Results (SEER) program. We used logistic regression with surgery as the binary outcome (subcutaneous, total, or radical mastectomy (STRM) versus partial mastectomy, no, unknown or other (PNUM)) and included additive effects of all the variables and interactions of age, stage, grade, and estrogen and progesterone receptors with race/ethnicity. Type I error of 5% was used to assess statistical significance of the effects. SA were significantly more likely than NHW cases to receive STRM relative to PNUM surgery among women diagnosed at or after age 50 years and having localized stage disease (Odds Ratio (OR) = 1.27, 95% Confidence Interval (CI) = 1.06 - 1.52). Further, SA were significantly less likely than NHW cases to receive STRM relative to PNUM surgery among those diagnosed before age 50 years and having regional or distant stage disease (OR = 0.75, 95% CI = 0.59 - 0.95 for age at diagnosis < 40 years; OR = 0.77, 95% CI = 0.62 - 0.95 for age at diagnosis 40-49 years). The type of surgery received by SA and NHW women differ according to age at diagnosis and disease stage.</p>","PeriodicalId":72177,"journal":{"name":"American journal of undergraduate research","volume":"18 3","pages":"15-23"},"PeriodicalIF":0.0,"publicationDate":"2021-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716021/pdf/nihms-1759518.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39774427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The aim of this research was to determine the relationship between pole vault warmup and competition performance in a sample of 16 collegiate vaulters over 60 observations. Pole vault athletes are given time to warm up in the same area that the competition will take place. This prompted investigation into whether better warmup performance could indicate better familiarity with the performance environment, and whether this could translate to the competition. The number of warmup vaults taken was also considered. Participants were observed during multiple warmup periods and data was collected on warmup performance. The findings indicate a significant correlation between instances in which participants displayed their best warmup scores and their best competition performances, likewise with their worst. Also, participants who took more warmup vaults performed significantly better on average. Athletes and coaches should consider implementing warmup practices that emphasize familiarizing oneself with their performance environment. KEYWORDS: Pole Vault; Track and Field; Warmups; Warmup Performance; Competition Performance; Performance Environment; Nested Task; Task Constraints
{"title":"Do Warmups Predict Pole Vault Competition Performance?","authors":"A. Peskin","doi":"10.33697/ajur.2021.044","DOIUrl":"https://doi.org/10.33697/ajur.2021.044","url":null,"abstract":"The aim of this research was to determine the relationship between pole vault warmup and competition performance in a sample of 16 collegiate vaulters over 60 observations. Pole vault athletes are given time to warm up in the same area that the competition will take place. This prompted investigation into whether better warmup performance could indicate better familiarity with the performance environment, and whether this could translate to the competition. The number of warmup vaults taken was also considered. Participants were observed during multiple warmup periods and data was collected on warmup performance. The findings indicate a significant correlation between instances in which participants displayed their best warmup scores and their best competition performances, likewise with their worst. Also, participants who took more warmup vaults performed significantly better on average. Athletes and coaches should consider implementing warmup practices that emphasize familiarizing oneself with their performance environment. KEYWORDS: Pole Vault; Track and Field; Warmups; Warmup Performance; Competition Performance; Performance Environment; Nested Task; Task Constraints","PeriodicalId":72177,"journal":{"name":"American journal of undergraduate research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46984531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The conversation of how to maximize the minimum distance between points - or, equivalently, pack congruent circles- in an equilateral triangle began by Oler in the 1960s. In a 1993 paper, Melissen proved the optimal placements of 4 through 12 points in an equilateral triangle using only partitions and direct applications of Dirichlet’s pigeon-hole principle. In the same paper, he proposed his conjectured optimal arrangements for 13, 14, 17, and 19 points in an equilateral triangle. In 1997, Payan proved Melissen’s conjecture for the arrangement of fourteen points; and, in September 2020, Joos proved Melissen’s conjecture for the optimal arrangement of thirteen points. These proofs completed the optimal arrangements of up to and including fifteen points in an equilateral triangle. Unlike Melissen’s proofs, however, Joos’s proof for the optimal arrangement of thirteen points in an equilateral triangle requires continuous functions and calculus. I propose that it is possible to continue Melissen’s line of reasoning, and complete an entirely discrete proof of Joos’s Theorem for the optimal arrangement of thirteen points in an equilateral triangle. In this paper, we make progress towards such a proof. We prove discretely that if either of two points is fixed, Joos’s Theorem optimally places the remaining twelve. KEYWORDS: optimization; packing; equilateral triangle; distance; circles; points; thirteen; maximize
{"title":"On Packing Thirteen Points in an Equilateral Triangle","authors":"Natalie Tedeschi","doi":"10.33697/ajur.2021.042","DOIUrl":"https://doi.org/10.33697/ajur.2021.042","url":null,"abstract":"The conversation of how to maximize the minimum distance between points - or, equivalently, pack congruent circles- in an equilateral triangle began by Oler in the 1960s. In a 1993 paper, Melissen proved the optimal placements of 4 through 12 points in an equilateral triangle using only partitions and direct applications of Dirichlet’s pigeon-hole principle. In the same paper, he proposed his conjectured optimal arrangements for 13, 14, 17, and 19 points in an equilateral triangle. In 1997, Payan proved Melissen’s conjecture for the arrangement of fourteen points; and, in September 2020, Joos proved Melissen’s conjecture for the optimal arrangement of thirteen points. These proofs completed the optimal arrangements of up to and including fifteen points in an equilateral triangle. Unlike Melissen’s proofs, however, Joos’s proof for the optimal arrangement of thirteen points in an equilateral triangle requires continuous functions and calculus. I propose that it is possible to continue Melissen’s line of reasoning, and complete an entirely discrete proof of Joos’s Theorem for the optimal arrangement of thirteen points in an equilateral triangle. In this paper, we make progress towards such a proof. We prove discretely that if either of two points is fixed, Joos’s Theorem optimally places the remaining twelve. KEYWORDS: optimization; packing; equilateral triangle; distance; circles; points; thirteen; maximize","PeriodicalId":72177,"journal":{"name":"American journal of undergraduate research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48605380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A circumstellar disk that surrounds a star is composed of gas, dust, and rocky objects that are in orbit around it. Around infant stars, this disk can act as a source of material that can be used to form planetesimals, which can then accrete more material and form into planets. Studying the mineral composition of these disks can provide insight into the processes that created our solar system. The purpose of this paper is to analyze the mineral composition of these disks by using a newly created python package, Min-CaLM. This package determines the relative mineral abundance within a disk by using a linear regression technique called non-negative least square minimization. The circumstellar disks that are capable of undergoing compositional analysis must have a spectrum with both a detectable mid-infrared excess and prominent silicate features. From our sample, there are only eight debris disks that qualify to be candidates for the Min-CaLM program. The mineral compositions calculated by Min-CaLM are then compared to the Tholen asteroid classification scheme. HD 23514, HD 105234, HD 15407A, BD+20 307, HD 69830, and HD 172555 are found to have a compositions similar to that expected for C-type asteroids, TYC 9410-532-1 resembles the composition of S-type asteroids, and HD 100546 resembles D-type asteroids. Min-CaLM also calculates the mineral compositions of the comets Tempel 1 and Hale-Bopp, and they are used as a comparison between the material in our early solar system and the debris disk compositions. KEYWORDS: Debris disk; Mineral; Composition; Analysis; Asteroid; Circumstellar; Spectroscopy; Python
{"title":"An Unbiased Mineral Compositional Analysis Technique for Circumstellar Disks","authors":"Y. Kipreos, I. Song","doi":"10.33697/ajur.2021.043","DOIUrl":"https://doi.org/10.33697/ajur.2021.043","url":null,"abstract":"A circumstellar disk that surrounds a star is composed of gas, dust, and rocky objects that are in orbit around it. Around infant stars, this disk can act as a source of material that can be used to form planetesimals, which can then accrete more material and form into planets. Studying the mineral composition of these disks can provide insight into the processes that created our solar system. The purpose of this paper is to analyze the mineral composition of these disks by using a newly created python package, Min-CaLM. This package determines the relative mineral abundance within a disk by using a linear regression technique called non-negative least square minimization. The circumstellar disks that are capable of undergoing compositional analysis must have a spectrum with both a detectable mid-infrared excess and prominent silicate features. From our sample, there are only eight debris disks that qualify to be candidates for the Min-CaLM program. The mineral compositions calculated by Min-CaLM are then compared to the Tholen asteroid classification scheme. HD 23514, HD 105234, HD 15407A, BD+20 307, HD 69830, and HD 172555 are found to have a compositions similar to that expected for C-type asteroids, TYC 9410-532-1 resembles the composition of S-type asteroids, and HD 100546 resembles D-type asteroids. Min-CaLM also calculates the mineral compositions of the comets Tempel 1 and Hale-Bopp, and they are used as a comparison between the material in our early solar system and the debris disk compositions. KEYWORDS: Debris disk; Mineral; Composition; Analysis; Asteroid; Circumstellar; Spectroscopy; Python","PeriodicalId":72177,"journal":{"name":"American journal of undergraduate research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48656392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Play behavior is widespread in juvenile mammals and may be a mechanism for practicing skills needed in adulthood. In mammals characterized by strong adult male competition over females, juvenile males perform more social play than do females, and such play may assist in later mating competition. This study examined whether social play behavior is sexually dimorphic in a polygamous neotropical primate, the squirrel monkey (Saimiri collinsi), through a six-week field study of two groups of wild monkeys in Eastern Amazonia, Brazil. We hypothesized that males would conduct more rough-and-tumble play than females and that any sex-based play differences would be more evident in older juveniles. We video recorded juvenile play bouts and scored: age category (younger or older juvenile) and sex of players (male or female); and rough-and-tumble play behaviors (i.e., bite, grab, and wrestle). Juvenile males initiated more play bouts than did females. Most players were older juvenile males, while older juvenile females were the least represented. Older juvenile play bouts occurred mostly among males, while younger juvenile bouts consisted of a more even sex distribution. While younger juveniles did not significantly affect the number of rough-and-tumble behaviors in bouts, the number of behaviors was significantly affected by the sex of older individuals. These results indicate that social play is sexually dimorphic in juvenile S. collinsi; specifically, males play more than females and sex differences are more pronounced in older cohorts. KEYWORDS: Squirrel Monkeys; Mating System; Sexual Dimorphism; Juvenile Period; Development; Play Behavior; Social Behavior; Ethology
{"title":"Is Play Sexually Dimorphic in the Polygamous Squirrel Monkey?","authors":"Seta Aghababian, A. Stone, C. Brown","doi":"10.33697/AJUR.2020.040","DOIUrl":"https://doi.org/10.33697/AJUR.2020.040","url":null,"abstract":"Play behavior is widespread in juvenile mammals and may be a mechanism for practicing skills needed in adulthood. In mammals characterized by strong adult male competition over females, juvenile males perform more social play than do females, and such play may assist in later mating competition. This study examined whether social play behavior is sexually dimorphic in a polygamous neotropical primate, the squirrel monkey (Saimiri collinsi), through a six-week field study of two groups of wild monkeys in Eastern Amazonia, Brazil. We hypothesized that males would conduct more rough-and-tumble play than females and that any sex-based play differences would be more evident in older juveniles. We video recorded juvenile play bouts and scored: age category (younger or older juvenile) and sex of players (male or female); and rough-and-tumble play behaviors (i.e., bite, grab, and wrestle). Juvenile males initiated more play bouts than did females. Most players were older juvenile males, while older juvenile females were the least represented. Older juvenile play bouts occurred mostly among males, while younger juvenile bouts consisted of a more even sex distribution. While younger juveniles did not significantly affect the number of rough-and-tumble behaviors in bouts, the number of behaviors was significantly affected by the sex of older individuals. These results indicate that social play is sexually dimorphic in juvenile S. collinsi; specifically, males play more than females and sex differences are more pronounced in older cohorts. KEYWORDS: Squirrel Monkeys; Mating System; Sexual Dimorphism; Juvenile Period; Development; Play Behavior; Social Behavior; Ethology","PeriodicalId":72177,"journal":{"name":"American journal of undergraduate research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48982727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The surge in vancomycin-resistant enterococci (VRE) strains poses a serious threat to public and clinical health. VRE strains are the leading cause of multi-drug resistant enterococcal infections and are commonly acquired from medical devices. Therefore, it is essential to discover new antibacterial targets and drugs for this pathogen. Alanine racemase could be a valuable drug target due to its crucial role in E. faecium survival. Alr from E. faecium (EF_Alr) was heterologously produced and purified from E. coli., and the steady-state kinetic constants were determined at different pH values. Using a coupled reaction with L-alanine dehydrogenase, rate of production of NADH was measured at 340 nm to observe EF_Alr activity in the D- to L-alanine direction. The highest catalytic efficiency, 8.61 ± 0.5 s-1 mM-1, was found at pH 9. Additionally, the tentative active site residues, Lys40 and Tyr268, for the alanine racemization reaction were assigned by homology modeling and sequence comparison studies. Using UCSF Chimera, the structure of the EF_Alr homology model was superimposed and compared to the crystal structure of Alr from E. faecalis. KEYWORDS: Alanine Racemase; Enterococcus faecium; Vancomycin-Resistant Enterococci; Homology Modeling; pH Optimum; Kinetic Characterization; SWISS-MODEL Server; Steady-State Kinetics
{"title":"Enzymatic and Structural Characterization of Alanine Racemase from Enterococcus faecium by Kinetic and Computational Studies","authors":"Arie Van Wieren, E. Bouchard, S. Majumdar","doi":"10.33697/AJUR.2020.039","DOIUrl":"https://doi.org/10.33697/AJUR.2020.039","url":null,"abstract":"The surge in vancomycin-resistant enterococci (VRE) strains poses a serious threat to public and clinical health. VRE strains are the leading cause of multi-drug resistant enterococcal infections and are commonly acquired from medical devices. Therefore, it is essential to discover new antibacterial targets and drugs for this pathogen. Alanine racemase could be a valuable drug target due to its crucial role in E. faecium survival. Alr from E. faecium (EF_Alr) was heterologously produced and purified from E. coli., and the steady-state kinetic constants were determined at different pH values. Using a coupled reaction with L-alanine dehydrogenase, rate of production of NADH was measured at 340 nm to observe EF_Alr activity in the D- to L-alanine direction. The highest catalytic efficiency, 8.61 ± 0.5 s-1 mM-1, was found at pH 9. Additionally, the tentative active site residues, Lys40 and Tyr268, for the alanine racemization reaction were assigned by homology modeling and sequence comparison studies. Using UCSF Chimera, the structure of the EF_Alr homology model was superimposed and compared to the crystal structure of Alr from E. faecalis. KEYWORDS: Alanine Racemase; Enterococcus faecium; Vancomycin-Resistant Enterococci; Homology Modeling; pH Optimum; Kinetic Characterization; SWISS-MODEL Server; Steady-State Kinetics","PeriodicalId":72177,"journal":{"name":"American journal of undergraduate research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43218079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emily Patterson, S. Eanes, Penelope Lancrete, Anne Gothman, P. Roback
Seawater temperature, salinity and carbonate chemistry have been shown to influence the uranium/calcium (U/Ca) ratios of scleractinian coral skeletons. This apparent sensitivity of U/Ca to multiple environmental parameters calls into question whether there is one environmental variable that most strongly controls coral U/Ca, and whether U/Ca can be straightforwardly applied as a paleoenvironmental proxy due to the tendency of environmental variables to covary in space and time. In this study, uranium concentration data from an existing compilation of tropical scleractinian coral U-series measurements is paired with environmental data from the World Ocean Atlas (WOA) and the Global Ocean Data Analysis Project (GLODAP) to examine the sensitivity of coral skeletal U/Ca to multiple seawater properties including temperature, salinity, pH, and saturation state. First, univariate linear regressions and multiple linear regressions were used to compare relationships between uranium and environmental parameters in the dataset with relationships observed in previous studies. Next, principal component analysis and regularized regression were used to identify the most likely predictors of coral U/Ca in order to create a multiple linear regression model. Results indicate that pH, Ω, alkalinity, and temperature are all significant predictors of uranium concentrations in coral. The magnitude and strength of relationships between U/Ca and environmental variables also differ across different genera. Seawater properties with strong correlations and small ranges make interpretation of these results difficult. However, results of these analyses indicate that U/Ca is dependent on multiple environmental parameters and that previously developed univariate regressions may be insufficient to characterize the full range of variables that influence coral [238U]. KEYWORDS: Coral; Paleoceanography; Proxy Calibration; Uranium; Multiple Linear Regression; Regularized Regression; Environmental Change; Oceanographic Databases
{"title":"Factors Controlling Coral Skeletal U/Ca Ratios with Implications for their Use as a Proxy for Past Ocean Conditions","authors":"Emily Patterson, S. Eanes, Penelope Lancrete, Anne Gothman, P. Roback","doi":"10.33697/AJUR.2020.031","DOIUrl":"https://doi.org/10.33697/AJUR.2020.031","url":null,"abstract":"Seawater temperature, salinity and carbonate chemistry have been shown to influence the uranium/calcium (U/Ca) ratios of scleractinian coral skeletons. This apparent sensitivity of U/Ca to multiple environmental parameters calls into question whether there is one environmental variable that most strongly controls coral U/Ca, and whether U/Ca can be straightforwardly applied as a paleoenvironmental proxy due to the tendency of environmental variables to covary in space and time. In this study, uranium concentration data from an existing compilation of tropical scleractinian coral U-series measurements is paired with environmental data from the World Ocean Atlas (WOA) and the Global Ocean Data Analysis Project (GLODAP) to examine the sensitivity of coral skeletal U/Ca to multiple seawater properties including temperature, salinity, pH, and saturation state. First, univariate linear regressions and multiple linear regressions were used to compare relationships between uranium and environmental parameters in the dataset with relationships observed in previous studies. Next, principal component analysis and regularized regression were used to identify the most likely predictors of coral U/Ca in order to create a multiple linear regression model. Results indicate that pH, Ω, alkalinity, and temperature are all significant predictors of uranium concentrations in coral. The magnitude and strength of relationships between U/Ca and environmental variables also differ across different genera. Seawater properties with strong correlations and small ranges make interpretation of these results difficult. However, results of these analyses indicate that U/Ca is dependent on multiple environmental parameters and that previously developed univariate regressions may be insufficient to characterize the full range of variables that influence coral [238U].\u0000KEYWORDS: Coral; Paleoceanography; Proxy Calibration; Uranium; Multiple Linear Regression; Regularized Regression; Environmental Change; Oceanographic Databases","PeriodicalId":72177,"journal":{"name":"American journal of undergraduate research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43635810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Graham, Douglas R Terrill, S. Boyd, Isabel Benjamin, Madeleine C Ward, M. Zimmerman
Although previous studies have examined the impact of comorbid major depressive disorder (MDD) on social anxiety disorder (SAD), the results have been somewhat mixed. Furthermore, most studies have been conducted in inpatient or outpatient settings. Given the large body of literature that suggests that this particular comorbidity can have negative effects on treatment efficacy and outcomes, it is important to continue to explore its impact. The present study aims to clarify contradictions in the literature and expands on previous studies by examining patients in a partial hospitalization setting. Patients at Rhode Island Hospital with a diagnosis of SAD were compared to those with comorbid SAD and MDD on pre-treatment and post-treatment measures of anxiety and depression. The results indicated that while the comorbid group showed significantly less improvement post-treatment on anxiety symptoms and constructs related to remission from depression, they did not show significantly less improvement on depression symptoms. The implications of these results for clinical practice are discussed. KEYWORDS: Social Anxiety Disorder; Major Depressive Disorder; Comorbid Anxiety Disorders; Comorbid Mood Disorders; Treatment Outcomes; Partial Hospitalization Program
{"title":"Treatment Outcomes in a Partial Hospital Program for Patients with Social Anxiety Disorder: The Effects of Comorbid Major Depression","authors":"A. Graham, Douglas R Terrill, S. Boyd, Isabel Benjamin, Madeleine C Ward, M. Zimmerman","doi":"10.33697/AJUR.2020.033","DOIUrl":"https://doi.org/10.33697/AJUR.2020.033","url":null,"abstract":"Although previous studies have examined the impact of comorbid major depressive disorder (MDD) on social anxiety disorder (SAD), the results have been somewhat mixed. Furthermore, most studies have been conducted in inpatient or outpatient settings. Given the large body of literature that suggests that this particular comorbidity can have negative effects on treatment efficacy and outcomes, it is important to continue to explore its impact. The present study aims to clarify contradictions in the literature and expands on previous studies by examining patients in a partial hospitalization setting. Patients at Rhode Island Hospital with a diagnosis of SAD were compared to those with comorbid SAD and MDD on pre-treatment and post-treatment measures of anxiety and depression. The results indicated that while the comorbid group showed significantly less improvement post-treatment on anxiety symptoms and constructs related to remission from depression, they did not show significantly less improvement on depression symptoms. The implications of these results for clinical practice are discussed. KEYWORDS: Social Anxiety Disorder; Major Depressive Disorder; Comorbid Anxiety Disorders; Comorbid Mood Disorders; Treatment Outcomes; Partial Hospitalization Program","PeriodicalId":72177,"journal":{"name":"American journal of undergraduate research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49512345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The Fibonacci sequence, whose first terms are f0; 1; 1; 2; 3; 5; : : :g, is generated using the recursive formula Fn+2 = Fn+1 + Fn with F0 = 0 and F1 = 1. This sequence is one of the most famous integer sequences because of its fascinating mathematical properties and connections with other fields such as biology, art, and music. Closely related to the Fibonacci sequence is the Lucas sequence. The Lucas sequence, whose first terms are f2; 1; 3; 4; 7; 11; : : :g, is generated using the recursive formula Ln+2 = Ln+1 + Ln with L0 = 2 and L1 = 1. In this paper, patterns in the prime factors of sums of powers of Fibonacci and Lucas numbers are examined. For example, F2 3n+4 + F2 3n+2 is even for all n 2 N0. To prove these results, techniques from modular arithmetic and facts about the divisibility of Fibonacci and Lucas numbers are utilized. KEYWORDS: Fibonacci Sequence; Lucas Sequence; Modular Arithmetic; Divisibility Sequence
{"title":"Prime Factors and Divisibility of Sums of Powers of Fibonacci and Lucas Numbers","authors":"Spirit Karcher, M. Michael","doi":"10.33697/AJUR.2020.036","DOIUrl":"https://doi.org/10.33697/AJUR.2020.036","url":null,"abstract":"The Fibonacci sequence, whose first terms are f0; 1; 1; 2; 3; 5; : : :g, is generated using the recursive formula Fn+2 = Fn+1 + Fn with F0 = 0 and F1 = 1. This sequence is one of the most famous integer sequences because of its fascinating mathematical properties and connections with other fields such as biology, art, and music. Closely related to the Fibonacci sequence is the Lucas sequence. The Lucas sequence, whose first terms are f2; 1; 3; 4; 7; 11; : : :g, is generated using the recursive formula Ln+2 = Ln+1 + Ln with L0 = 2 and L1 = 1. In this paper, patterns in the prime factors of sums of powers of Fibonacci and Lucas numbers are examined. For example, F2 3n+4 + F2 3n+2 is even for all n 2 N0. To prove these results, techniques from modular arithmetic and facts about the divisibility of Fibonacci and Lucas numbers are utilized. KEYWORDS: Fibonacci Sequence; Lucas Sequence; Modular Arithmetic; Divisibility Sequence","PeriodicalId":72177,"journal":{"name":"American journal of undergraduate research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46742415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna B. Stockstad, E. Gray, S. Sebestyen, Nina K. Lany, R. Kolka, M. Windmuller-Campione
Water table fluctuations in peatlands are closely coupled with the local climate setting and drive critical ecosystem processes such as nutrient cycling. In Minnesota, USA, peatlands cover ten percent of the surface area, approximately 2.5 million hectares, some of which are actively managed for forest products. To explore the relationship between peatland water tables and precipitation, long-term data (1961 to 2019) were used from the Marcell Experimental Forest in northern Minnesota. Starting in 1961, water table data from seven peatlands, including two types of peatlands (bogs and fens), were measured. We used the Theil-Sen estimator to test for monotonic trends in mean monthly water table elevations for individual peatlands and monthly precipitation. Water levels in bogs were both more variable and had mean water table elevations that were closer to the surface. Individual trends of water table elevations differed among peatlands. Water table elevations increased over time in three of the bogs studied and decreased over time in two of the bogs studied. Trends within fens were notably nonlinear across time. No significant linear trend was found for mean monthly precipitation between 1961 and 2019. These results highlight differences in peatlands types, local physiography, and the importance of understanding how changes in long-term dynamics coupled with changing current conditions will influence the effects of water table fluctuations on ecosystem services. The variability of water table elevations in bogs poses potential difficulties in modeling these ecosystems or creating adaptive management plans. KEYWORDS: Peatlands; Hydrology; Water tables; Bogs; Fens; Monitoring; Minnesota; Climate Change
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