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Strategies for increasing the use of tranexamic acid in patients undergoing major surgery* 大手术患者增加氨甲环酸使用的策略*
IF 0.8 Q3 ANESTHESIOLOGY Pub Date : 2024-11-28 DOI: 10.1002/anr3.12335
L. Murphy, S. R. Warnakulasuriya

Tranexamic acid reduces major bleeding events in patients undergoing major surgery without increasing thromboembolic events. In October 2022, the Joint Royal Colleges Tranexamic Acid in Surgery Implementation Group issued recommendations for consideration of tranexamic acid use in all patients having inpatient surgery. National and local audit data shows that a significant portion of eligible patients do not receive tranexamic acid. We designed and implemented a quality improvement project to increase the use of tranexamic acid in patients undergoing major surgery (surgery with the potential for estimated blood loss > 500 ml). Data were collected on baseline tranexamic acid use and stakeholder-reported barriers to tranexamic acid use. This was used to design and implement a sequence of quality improvement interventions. We disseminated Joint Royal Colleges guidance and delivered education sessions to increase understanding of tranexamic acid use. The local World Health Organisation (WHO) surgical checklist was updated to prompt clinical staff to consider the use of tranexamic acid. At baseline tranexamic acid was used in 50 of 100 (50%) major surgical cases. In the third audit cycle, tranexamic acid use had improved to 65 of 96 (68%) cases, with a shift in practice noted on continuous monitoring data indicating sustained improvement. Key factors in successful implementation of this project included stakeholder engagement, widespread dissemination of education and guidance and change of the local WHO surgical checklist.

氨甲环酸可减少大手术患者的大出血事件,而不增加血栓栓塞事件。2022年10月,联合皇家学院手术中氨甲环酸实施小组发布了建议,建议所有住院手术患者考虑使用氨甲环酸。国家和地方审计数据显示,相当一部分符合条件的患者没有接受氨甲环酸治疗。我们设计并实施了一项质量改进项目,以增加接受大手术(估计可能失血量为500毫升的手术)患者氨甲环酸的使用。收集了有关氨甲环酸基线使用和利益相关者报告的氨甲环酸使用障碍的数据。这被用于设计和实施一系列质量改进干预措施。我们传播了联合皇家学院指南,并举办了教育会议,以提高对氨甲环酸使用的理解。更新了本地的世界卫生组织(世卫组织)手术清单,以促使临床工作人员考虑使用氨甲环酸。在基线时,100例(50%)大手术病例中有50例使用氨甲环酸。在第三个审计周期中,氨甲环酸的使用已改善到96例中的65例(68%),连续监测数据表明,实践中的转变表明持续改善。成功实施该项目的关键因素包括利益攸关方的参与、教育和指导的广泛传播以及当地世卫组织手术清单的改变。
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引用次数: 0
Peri-operative and anaesthetic considerations for gender-affirming vocal surgery 性别确认发声手术的围手术期和麻醉注意事项
IF 0.8 Q3 ANESTHESIOLOGY Pub Date : 2024-11-21 DOI: 10.1002/anr3.12336
A. Lim, J. Myatt, D. Inglis, C. Al Yaghchi

The number of people identifying as transgender and/or gender diverse has increased significantly in recent years. As there are no pharmacologic options for raising vocal pitch and voice therapy may have limited benefit, vocal feminisation surgery is important for this group of patients. It is important for clinicians to be aware of the procedures which may be carried out and the implications for subsequent airway management. In this article, we present the case of a 46-year-old transgender woman who underwent gender-affirming vocal surgery. We will discuss the modified Wendler glottoplasty surgical technique, anaesthetic management and postoperative recovery. We also discuss future peri-operative implications, including airway management for those undergoing general anaesthesia for subsequent operations.

近年来,被认定为变性人和/或性别多元化的人数大幅增加。由于没有药物可以提高声调,嗓音治疗的效果也很有限,因此声带女性化手术对这类患者非常重要。临床医生必须了解可能进行的手术以及对后续气道管理的影响。在本文中,我们将介绍一名 46 岁变性女性接受性别确认发声手术的病例。我们将讨论改良 Wendler 声门成形术的手术技巧、麻醉管理和术后恢复。我们还将讨论未来围手术期的影响,包括为后续手术进行全身麻醉时的气道管理。
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引用次数: 0
The impact of neck flexion on ventilation and glottic visualisation in a child with Treacher Collins syndrome. 屈颈对特雷撤-科林斯综合征患儿通气和声门视野的影响。
IF 0.8 Q3 ANESTHESIOLOGY Pub Date : 2024-11-18 eCollection Date: 2024-07-01 DOI: 10.1002/anr3.12333
V Mazandi, L Grosinger, C Ward, R Daly Guris

We report the airway management of an 11-year-old boy with Treacher Collins syndrome. In three instances under general anaesthesia, ventilation via either anaesthesia facemask or supraglottic airway device proved virtually impossible except when the neck was flexed, which runs counter to what is typically observed during routine anaesthetic care. In this report, the impact of neck flexion on the patient's airway is demonstrated with images obtained on videolaryngoscopy and flexible endoscopy. It is prudent to manage airways using validated techniques and established algorithms. Nonetheless, airway management can benefit from atypical measures.

我们报告了一名患有特雷撤-科林斯综合征的11岁男孩的气道治疗情况。事实证明,在三次全身麻醉中,除非颈部弯曲,否则通过麻醉面罩或声门上气道装置进行通气几乎是不可能的,这与常规麻醉护理中通常观察到的情况背道而驰。本报告通过视频喉镜和柔性内窥镜获得的图像展示了颈部弯曲对患者气道的影响。使用经过验证的技术和既定算法管理气道是谨慎之举。然而,气道管理也可以从非典型措施中获益。
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引用次数: 0
High spinal anaesthesia during local anaesthetic skin infiltration at the cervical facet joint 颈椎面关节局部麻醉皮肤浸润时的高位脊髓麻醉
IF 0.8 Q3 ANESTHESIOLOGY Pub Date : 2024-11-18 DOI: 10.1002/anr3.12334
J. C. H. Goh, Y. M. Gn, D. J. A. Tan, Z. W. Lim

Facet joint injections are generally safe to perform with a low incidence of adverse events. There are few published reports of neurological complications occurring following procedures at the facet joint or cervical epidural space. However, complications from local anaesthetic infiltration to the skin and surrounding tissue have not been reported. We report a case of transient tetraplegia after local anaesthetic infiltration to the skin in preparation for cervical facet joint injection. We discuss potential reasons for this complication and suggest practice modifications which could reduce the risk.

面关节注射通常是安全的,不良反应发生率较低。关于在面关节或颈椎硬膜外腔进行手术后出现神经系统并发症的公开报道很少。然而,局麻药渗入皮肤和周围组织引起的并发症尚未见报道。我们报告了一例在颈椎面关节注射准备过程中局部麻醉剂渗入皮肤后引起的一过性四肢瘫痪病例。我们讨论了这一并发症的潜在原因,并提出了可降低风险的操作方法。
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引用次数: 0
The impact of neck flexion on ventilation and glottic visualisation in a child with Treacher Collins syndrome 屈颈对特雷撤-科林斯综合征患儿通气和声门视野的影响
IF 0.8 Q3 ANESTHESIOLOGY Pub Date : 2024-11-18 DOI: 10.1002/anr3.12333
V. Mazandi, L. Grosinger, C. Ward, R. Daly Guris

We report the airway management of an 11-year-old boy with Treacher Collins syndrome. In three instances under general anaesthesia, ventilation via either anaesthesia facemask or supraglottic airway device proved virtually impossible except when the neck was flexed, which runs counter to what is typically observed during routine anaesthetic care. In this report, the impact of neck flexion on the patient's airway is demonstrated with images obtained on videolaryngoscopy and flexible endoscopy. It is prudent to manage airways using validated techniques and established algorithms. Nonetheless, airway management can benefit from atypical measures.

我们报告了一名患有特雷撤-科林斯综合征的11岁男孩的气道管理情况。事实证明,在三次全身麻醉中,除非颈部弯曲,否则通过麻醉面罩或声门上气道装置进行通气几乎是不可能的,这与常规麻醉护理中通常观察到的情况背道而驰。本报告通过视频喉镜和柔性内窥镜获得的图像展示了颈部弯曲对患者气道的影响。使用经过验证的技术和既定算法管理气道是谨慎之举。然而,气道管理也可以受益于非典型措施。
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引用次数: 0
Cardiac arrest during alveolar recruitment manoeuvre under general anaesthesia for laparoscopic surgery 腹腔镜手术全身麻醉下进行肺泡扩张操作时心脏骤停
IF 0.8 Q3 ANESTHESIOLOGY Pub Date : 2024-11-04 DOI: 10.1002/anr3.12332
M. C. Larsen, U. K. Soni

A 67-year-old woman with no history of cardiovascular disease, undergoing an elective laparoscopic cholecystectomy, experienced severe bradycardia and cardiac arrest immediately following an alveolar recruitment manoeuvre under general anaesthesia. Prompt cardiopulmonary resuscitation restored cardiac output within 2–3 min. Postoperatively, she remained stable and was discharged following 24 h of monitoring. The cardiac arrest was likely triggered by vagal nerve stimulation and activation of intrinsic cardiac reflexes by the alveolar recruitment manoeuvre. The event emphasises a rare, but significant, risk of the routine management of pulmonary atelectasis.

一名没有心血管疾病史的 67 岁女性在接受择期腹腔镜胆囊切除术时,在全身麻醉下进行肺泡扩张操作后立即出现严重心动过缓和心跳骤停。及时的心肺复苏在 2-3 分钟内恢复了心输出量。术后,她的病情保持稳定,经过 24 小时的监护后出院。心脏骤停很可能是由于迷走神经受到刺激以及肺泡募集动作激活了心脏固有反射而引发的。该事件强调了常规肺不张治疗的一个罕见但重大的风险。
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引用次数: 0
Retrodural space: a cadaveric evaluation 视网膜间隙:尸体评估
IF 0.8 Q3 ANESTHESIOLOGY Pub Date : 2024-10-17 DOI: 10.1002/anr3.12323
H. Elsharkawy, K. Lebak, A. Crofton, S. E. Pope, P. A. Traxler, S. A. Baraka, L. E. Tollinche

The retrodural space is an interfascial tissue plane located between the ligamentum flavum and the interspinous ligament [1-3]. The ligamentum flavum forms a barrier between the retrodural and epidural spaces; however, theoretically normal gaps can allow the spread of medications into the epidural space [4]. Therefore, this space can be a potential location for injecting local anaesthetics, leading to their spread into the dorsal rami, neural foramen and epidural space.

We investigated this technique in one unembalmed cadaver to determine the distribution of local anaesthetic and dye after injection into the lumbar retrodural space. Anterior–posterior fluoroscopic and ultrasound imaging (a curved array transducer in the transverse window between the L3 and L4 vertebrae) were used to guide the injection. An 18-gauge Tuohy needle was advanced in-plane from lateral to medial (left paramedian approach) (Fig. 1a). Once the needle tip was identified superficial to the ligamentum flavum with ultrasound and increased tactile resistance was noted, 6 ml of lidocaine 1% mixed with 0.5 ml methylene blue and 3.5 ml of iodinated contrast agent was injected (Fig. 1b).

We observed staining in the tissue plane deep (anterior) to the erector spinae muscles from T12 to L5 (Fig. 2a). The intact facet joints showed dye spread around the capsule (Fig. 2b). The lumbar dorsal root ganglion, the dura and the spinal nerves showed no staining (Fig. 2c).

This is the first cadaveric study of intentional injection into the retrodural space. This technique may prove useful for posterior truncal wall coverage as it allows the dorsal rami to be blocked.

The authors state that every effort was made to follow all local and international ethical guidelines and laws pertaining to the use of human cadaveric donors in anatomical research.

硬膜后间隙是位于黄韧带和棘间韧带之间的筋膜间组织平面[1-3]。黄韧带在硬膜后间隙和硬膜外间隙之间形成一道屏障;然而,理论上正常的间隙可使药物扩散到硬膜外间隙[4]。因此,该间隙可能是注射局麻药的潜在位置,导致局麻药扩散到背侧韧带、神经孔和硬膜外间隙。我们在一具无尸体上研究了这种技术,以确定局麻药和染料注射到腰椎硬膜后间隙后的分布情况。我们使用前后透视和超声成像(在 L3 和 L4 椎体之间的横向窗口使用曲面阵列传感器)来引导注射。在平面内将 18 号 Tuohy 针头从外侧向内侧推进(左侧旁路)(图 1a)。一旦用超声波确定针尖位于黄韧带浅表,并注意到触觉阻力增加,就注射 6 毫升 1%利多卡因混合 0.5 毫升亚甲蓝和 3.5 毫升碘化造影剂(图 1b)。我们观察到从 T12 到 L5 的竖脊肌组织平面深部(前方)染色(图 2a)。完整的面关节显示染料在关节囊周围扩散(图 2b)。腰椎背根神经节、硬膜和脊神经未显示染色(图 2c)。作者指出,在使用人体尸体捐献者进行解剖研究时,我们尽了一切努力遵守所有当地和国际伦理准则和法律。
{"title":"Retrodural space: a cadaveric evaluation","authors":"H. Elsharkawy,&nbsp;K. Lebak,&nbsp;A. Crofton,&nbsp;S. E. Pope,&nbsp;P. A. Traxler,&nbsp;S. A. Baraka,&nbsp;L. E. Tollinche","doi":"10.1002/anr3.12323","DOIUrl":"https://doi.org/10.1002/anr3.12323","url":null,"abstract":"<p>The retrodural space is an interfascial tissue plane located between the ligamentum flavum and the interspinous ligament [<span>1-3</span>]. The ligamentum flavum forms a barrier between the retrodural and epidural spaces; however, theoretically normal gaps can allow the spread of medications into the epidural space [<span>4</span>]. Therefore, this space can be a potential location for injecting local anaesthetics, leading to their spread into the dorsal rami, neural foramen and epidural space.</p><p>We investigated this technique in one unembalmed cadaver to determine the distribution of local anaesthetic and dye after injection into the lumbar retrodural space. Anterior–posterior fluoroscopic and ultrasound imaging (a curved array transducer in the transverse window between the L3 and L4 vertebrae) were used to guide the injection. An 18-gauge Tuohy needle was advanced in-plane from lateral to medial (left paramedian approach) (Fig. 1a). Once the needle tip was identified superficial to the ligamentum flavum with ultrasound and increased tactile resistance was noted, 6 ml of lidocaine 1% mixed with 0.5 ml methylene blue and 3.5 ml of iodinated contrast agent was injected (Fig. 1b).</p><p>We observed staining in the tissue plane deep (anterior) to the erector spinae muscles from T12 to L5 (Fig. 2a). The intact facet joints showed dye spread around the capsule (Fig. 2b). The lumbar dorsal root ganglion, the dura and the spinal nerves showed no staining (Fig. 2c).</p><p>This is the first cadaveric study of intentional injection into the retrodural space. This technique may prove useful for posterior truncal wall coverage as it allows the dorsal rami to be blocked.</p><p>The authors state that every effort was made to follow all local and international ethical guidelines and laws pertaining to the use of human cadaveric donors in anatomical research.</p>","PeriodicalId":72186,"journal":{"name":"Anaesthesia reports","volume":"12 2","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/anr3.12323","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142447836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An exploration of the cognitive and affective processes for anaesthetists when performing an emergency front of neck airway* 探索麻醉师在实施紧急颈前气道时的认知和情感过程。
IF 0.8 Q3 ANESTHESIOLOGY Pub Date : 2024-10-07 DOI: 10.1002/anr3.12331
L. R. Kidd, P. Wegrzynek, C. Newell, E. Wainwright

Emergency front of neck airway (eFONA) is a potentially lifesaving but very high-stress procedure. We explored the cognitive and affective processes involved via semi-structured interviews with 17 UK anaesthetists who had attempted eFONA within the previous two years. Thematic analyses generated two meta-themes: ‘Making the decision is the hardest part; the doing is easier’ and ‘What helps make the decision?’. We found concerns around scrutiny, lack of a flat hierarchy, unfamiliarity with the situation and the lack of a model for transitioning to eFONA. Culture change, using a shared mental model, priming and emotional disengagement, assisted with eFONA decision-making. Conclusions and implications for practice are presented.

紧急颈前气道(eFONA)是一项可能挽救生命但压力非常大的手术。我们通过对 17 名在过去两年内尝试过 eFONA 的英国麻醉师进行半结构化访谈,探讨了其中涉及的认知和情感过程。主题分析产生了两个元主题:"做出决定是最难的部分;做起来比较容易 "和 "什么有助于做出决定?我们发现了对审查、缺乏扁平化等级制度、不熟悉情况以及缺乏向 eFONA 过渡的模式的担忧。文化变革、共同心智模式、引子和情感脱离有助于 eFONA 决策。本文提出了结论和对实践的启示。
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引用次数: 0
Facial fire with use of high-flow nasal oxygen during laser surgery 在激光手术中使用高流量鼻氧时面部起火。
IF 0.8 Q3 ANESTHESIOLOGY Pub Date : 2024-10-07 DOI: 10.1002/anr3.12329
S. Shankla, N. De Zoysa, J. Bird, M. Girgis

Use of high-flow nasal oxygen to enable apnoeic oxygenation during tubeless airway surgery is well-established. The use of an ignition source in this oxygen-rich environment increases the risk of surgical fire. We present a case of facial fire secondary to the use of carbon dioxide laser and high-flow nasal oxygen during a surgical procedure for subglottic stenosis. The incident occurred when the laser was being tested near the patient, resulting in superficial burns to the patient's face and neck. The airway was unaffected and the burns were managed conservatively. This case highlights important safety consideration for the use of an ignition source in the presence of high-flow nasal oxygen and the role of human factors and in-built risk mitigation features.

在无管气道手术中使用高流量鼻氧来实现无呼吸吸氧已得到广泛认可。在这种富氧环境中使用火源会增加手术起火的风险。我们介绍了一例在声门下狭窄手术过程中因使用二氧化碳激光和高流量鼻氧而继发面部起火的病例。事故发生时,激光正在患者附近进行测试,导致患者面部和颈部表皮烧伤。气道未受影响,烧伤也得到了保守治疗。该案例强调了在高流量鼻氧存在的情况下使用点火源的重要安全考虑因素,以及人为因素和内置风险缓解功能的作用。
{"title":"Facial fire with use of high-flow nasal oxygen during laser surgery","authors":"S. Shankla,&nbsp;N. De Zoysa,&nbsp;J. Bird,&nbsp;M. Girgis","doi":"10.1002/anr3.12329","DOIUrl":"10.1002/anr3.12329","url":null,"abstract":"<div>\u0000 \u0000 <p>Use of high-flow nasal oxygen to enable apnoeic oxygenation during tubeless airway surgery is well-established. The use of an ignition source in this oxygen-rich environment increases the risk of surgical fire. We present a case of facial fire secondary to the use of carbon dioxide laser and high-flow nasal oxygen during a surgical procedure for subglottic stenosis. The incident occurred when the laser was being tested near the patient, resulting in superficial burns to the patient's face and neck. The airway was unaffected and the burns were managed conservatively. This case highlights important safety consideration for the use of an ignition source in the presence of high-flow nasal oxygen and the role of human factors and in-built risk mitigation features.</p>\u0000 </div>","PeriodicalId":72186,"journal":{"name":"Anaesthesia reports","volume":"12 2","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A novel application of the Hyperflex™ tracheostomy tube for lung isolation in a patient with airway stoma after laryngectomy 将 Hyperflex™ 气管造口管用于喉切除术后气道造口患者肺隔离的新应用。
IF 0.8 Q3 ANESTHESIOLOGY Pub Date : 2024-10-03 DOI: 10.1002/anr3.12328
P. Maurya, N. Gupta, E. Dhamija, V. Kumar

In patients who have undergone laryngectomy followed by permanent tracheostomy, managing the airway for one-lung ventilation during lung surgery may present a challenge for anaesthetists. This case report discusses a 45-year-old man with a permanent tracheostomy after a laryngectomy performed for laryngeal carcinoma 5 years ago. He was scheduled to undergo excision of a right bronchial mass for which one-lung ventilation was required. An adjustable Flange Hyperflex™ Tracheostomy tube (Bivona® Silicone Tracheostomy tube, Smiths Medical ASD, Inc., Gary, Indiana, USA) was used for this purpose and the tube was guided into the left main bronchus with a bronchoscope. Appropriate lung isolation was achieved using this technique, and there were no airway-related complications during or after the surgery. This case report shows that a Hyperflex™ tracheostomy tube can be successfully utilised in challenging airway scenarios in patients with a tracheostomy, where other options may not be feasible.

对于接受喉切除术后又进行了永久性气管造口术的患者,在肺部手术期间进行单肺通气的气道管理可能会给麻醉师带来挑战。本病例报告所讨论的患者是一名 45 岁的男性,5 年前因喉癌接受了喉切除术,术后实施了永久性气管造口术。他计划接受右支气管肿块切除术,需要进行单肺通气。为此,他使用了可调法兰 Hyperflex™ 气管造口管(Bivona® 硅胶气管造口管,Smiths Medical ASD 公司,美国印第安纳州加里市),并用支气管镜将该管导入左主支气管。使用该技术实现了适当的肺隔离,术中和术后均未出现气道相关并发症。本病例报告表明,Hyperflex™气管造口管可成功用于气管造口术患者的挑战性气道情况,而其他方案可能并不可行。
{"title":"A novel application of the Hyperflex™ tracheostomy tube for lung isolation in a patient with airway stoma after laryngectomy","authors":"P. Maurya,&nbsp;N. Gupta,&nbsp;E. Dhamija,&nbsp;V. Kumar","doi":"10.1002/anr3.12328","DOIUrl":"10.1002/anr3.12328","url":null,"abstract":"<div>\u0000 \u0000 <p>In patients who have undergone laryngectomy followed by permanent tracheostomy, managing the airway for one-lung ventilation during lung surgery may present a challenge for anaesthetists. This case report discusses a 45-year-old man with a permanent tracheostomy after a laryngectomy performed for laryngeal carcinoma 5 years ago. He was scheduled to undergo excision of a right bronchial mass for which one-lung ventilation was required. An adjustable Flange Hyperflex™ Tracheostomy tube (Bivona® Silicone Tracheostomy tube, Smiths Medical ASD, Inc., Gary, Indiana, USA) was used for this purpose and the tube was guided into the left main bronchus with a bronchoscope. Appropriate lung isolation was achieved using this technique, and there were no airway-related complications during or after the surgery. This case report shows that a Hyperflex™ tracheostomy tube can be successfully utilised in challenging airway scenarios in patients with a tracheostomy, where other options may not be feasible.</p>\u0000 </div>","PeriodicalId":72186,"journal":{"name":"Anaesthesia reports","volume":"12 2","pages":""},"PeriodicalIF":0.8,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142382588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Anaesthesia reports
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