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Applied radiation oncology最新文献

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Integrating MR-Guided Radiation Therapy Into Clinical Practice: Clinical Advantages and Practical Limitations 将核磁共振引导放射治疗纳入临床实践:临床优势与实践局限性
Pub Date : 2021-09-01 DOI: 10.37549/aro1289
L. Tchelebi, Nicholas G Zaorsky, J. Rosenberg, K. Latifi, Sarah Hoffe
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引用次数: 0
Improving Cancer Equity Through Advocacy 通过倡导改善癌症公平
Pub Date : 2021-09-01 DOI: 10.37549/aro1286
G. Vidal
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引用次数: 0
Time-Driven Activity-Based Costing of CT-Guided vs MR-Guided Prostate SBRT. 基于时间驱动的活动成本计算:CT 引导与 MR 引导的前列腺 SBRT 比较
Pub Date : 2021-09-01 Epub Date: 2021-10-05
Neil R Parikh, Mary Ann Clark, Parashar Patel, Kayla Kafka-Peterson, Lalaine Zaide, Ting Martin Ma, Michael L Steinberg, Minsong Cao, Ann C Raldow, James Lamb, Amar U Kishan
<p><strong>Background and purpose: </strong>Stereotactic body radiation therapy (SBRT) has become a standard-of-care option for localized prostate cancer. While prostate SBRT has traditionally been delivered using computed-tomography-guided radiation therapy (CTgRT), MR-imaging-guided radiation therapy (MRgRT) is now available. MRgRT offers real-time soft-tissue visualization and ease of adaptive planning, obviating the need for fiducial markers, and potentially allowing for smaller planning target volume (PTV) margins. Although prior studies have focused on evaluating the cost-effectiveness of MRgRT vs CTgRT from a payor perspective, the difference in provider costs to deliver such treatments remains unknown. This study thus used time-driven activity-based costing (TDABC) to determine the difference in provider resources consumed by delivering prostate SBRT via MRgRT vs CTgRT.</p><p><strong>Methods: </strong>Data was collected from a single academic institution where prostate SBRT is routinely performed using both CTgRT and MRgRT. Five-fraction SBRT (40 Gy total dose) was assumed to be delivered through volumetric-modulated arc therapy for CTgRT patients, and through step-and-shoot, fixed-gantry intensity-modulated radiation therapy for MRgRT patients. Process maps were constructed for each portion of the radiation delivery process via interviews/surveys with departmental personnel and by measuring CTgRT and MRgRT treatment times. Prior to simulation, only CTgRT patients underwent placement of three gold fiducial markers. Personnel capacity cost rates were calculated by dividing total personnel costs by the annual minutes worked by a given personnel. Equipment costs included both an annualized purchase price and annual maintenance costs. Ultimately, the total costs of care encompassing personnel, space/equipment, and materials were aggregated across the entire chain of care for both CTgRT and MRgRT patients in a base case.</p><p><strong>Results: </strong>Direct costs associated with delivering a 5-fraction course of prostate SBRT were $1,497 higher with MRgRT than with CTgRT - comprised of personnel costs ($210 higher with MRgRT), space/equipment ($1,542 higher with MRgRT), and materials ($255 higher with CTgRT). Only CTgRT patients underwent fiducial placement, which accounted for $591. MRgRT patients were assumed to undergo both CT simulation (for electron density calculation) and MRI simulation, with the former accounting for $168. Mean time spent by patients in the treatment vault per fraction was 20 minutes (range 15-26 minutes) for CTgRT, and 31 minutes (range 30-34 minutes) for MRgRT. Patient time spent during fiducial placement (CTgRT only) was 60 minutes. Modifying the number of fractions treated would result in the cost difference of $1,497 (5 fractions) changing to $441 (1 fraction) or to $2,025 (7 fractions).</p><p><strong>Conclusion: </strong>This study provides an approximate comparison of the direct resources required for a radiat
背景和目的:立体定向体放射治疗(SBRT)已成为局部前列腺癌的标准治疗方案。前列腺 SBRT 传统上采用计算机断层扫描引导的放射治疗(CTgRT),而现在则有了磁共振成像引导的放射治疗(MRgRT)。MRgRT 提供实时软组织可视化,易于自适应规划,无需靶标,并有可能缩小规划靶体积 (PTV) 边界。尽管之前的研究侧重于从支付方的角度评估 MRgRT 与 CTgRT 的成本效益,但提供此类治疗的医疗服务提供者的成本差异仍是未知数。因此,本研究采用基于时间驱动活动的成本计算(TDABC)来确定通过 MRgRT 与 CTgRT 进行前列腺 SBRT 所消耗的医疗资源差异:数据收集自一家学术机构,该机构常规使用 CTgRT 和 MRgRT 进行前列腺 SBRT 治疗。假定 CTgRT 患者通过容积调制弧线疗法进行五分次 SBRT(总剂量为 40 Gy),而 MRgRT 患者通过步进射频、固定机架调强放射疗法进行五分次 SBRT(总剂量为 40 Gy)。通过对科室人员进行访谈/调查,并通过测量 CTgRT 和 MRgRT 治疗时间,为放射治疗过程的每个部分绘制了流程图。在模拟之前,只有 CTgRT 患者进行了三个金靶标的放置。人员能力成本率的计算方法是将人员总成本除以特定人员的年工作时间。设备成本包括年化购买价格和年维护成本。最终,在基础病例中,对 CTgRT 和 MRgRT 患者的整个护理链中的人员、空间/设备和材料等护理总成本进行了汇总:与前列腺 SBRT 5 个疗程相关的直接成本,MRgRT 比 CTgRT 高出 1,497 美元,其中包括人员成本(MRgRT 高出 210 美元)、空间/设备成本(MRgRT 高出 1542 美元)和材料成本(CTgRT 高出 255 美元)。只有 CTgRT 患者进行了靶标置入,所需费用为 591 美元。假定 MRgRT 患者同时进行 CT 模拟(用于电子密度计算)和 MRI 模拟,前者的费用为 168 美元。CTgRT 和 MRgRT 患者在治疗室中花费的平均时间分别为 20 分钟(15-26 分钟不等)和 31 分钟(30-34 分钟不等)。患者放置靶标(仅 CTgRT)的时间为 60 分钟。如果改变治疗的分数,成本差异将从1,497美元(5个分数)变为441美元(1个分数)或2,025美元(7个分数):本研究提供了放射肿瘤服务提供者使用 CTgRT 与 MRgRT 进行前列腺 SBRT 所需的直接资源的大致比较。我们正在等待目前正在进行的 MIRAGE III 期试验的结果,该试验正在对这些模式进行比较,随后将对急性和晚期泌尿生殖系统/胃肠道(GU/GI)毒性、生活质量结果的时间变化以及 5 年无生化、无复发生存率进行测量。比较 MRgRT 与 CTgRT 的疗效和安全性的研究结果最终将使我们能够明确成本差异。
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引用次数: 0
Celebrating 10 Years 庆祝十周年
Pub Date : 2021-09-01 DOI: 10.37549/aro1283
J. Suh
What does it mean to teach and learn within and with virtual environments? It means that we as learners are no longer engaged in one way interactions, but dynamic interactions. Virtual environments have enabled us to be highly immersed in spaces that yield high social presence, constructivist learning, interactive problem solving, and are surprisingly still enjoyable. This keynote address focuses on teaching and learning in Multi-User Virtual Environments. Concrete examples are presented on how to engage learners in a virtual world webquest, entrepreneurship, community development and civic engagement. Other uses of virtual environments for e-learning are discussed.
在虚拟环境中进行教学意味着什么?这意味着我们作为学习者不再参与单向互动,而是动态互动。虚拟环境使我们能够高度沉浸在产生高度社会存在感、建构主义学习、交互式问题解决的空间中,并且令人惊讶地仍然令人愉快。本主题演讲的重点是多用户虚拟环境中的教学。介绍了如何让学习者参与虚拟世界网络探索、创业、社区发展和公民参与的具体例子。讨论了虚拟环境在电子学习中的其他用途。
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引用次数: 5
FLASH Stance — Updates in Ultrahigh Dose Rate Radiation Therapy FLASH立场——超高剂量率放射治疗的最新进展
Pub Date : 2021-06-01 DOI: 10.37549/aro1279
M. B. Massat
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引用次数: 0
Measured Distribution of Total Red Bone Marrow in Young Children 幼儿总红骨髓分布的测定
Pub Date : 2021-06-01 DOI: 10.37549/aro1273
I. Abu-Gheida, Arwa A. Zaghal, L. Naffaa, P. Taddei
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引用次数: 0
FLASH Into View: Clinical Implications of Ultrahigh Dose Rate RT FLASH进入视野:超高剂量率RT的临床意义
Pub Date : 2021-06-01 DOI: 10.37549/aro1275
J. Suh
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引用次数: 0
The Role of Patient Reported Outcomes in Esophageal Cancer Patients Receiving Chemoradiation Therapy 患者报告的结果在食管癌患者接受放化疗中的作用
Pub Date : 2021-06-01 DOI: 10.37549/aro1277
J. McDonald, A. Sim, J. Frakes, H. Yu, R. Nanda, D. Portman, S. Hoffe, H. Jim, P. Johnstone
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引用次数: 0
Medical School Curricula: Giving Radiation Oncology a Seat at the Table 医学院课程:让放射肿瘤学在餐桌上占有一席之地
Pub Date : 2021-06-01 DOI: 10.37549/aro1278
S. Dooley, A. Chaurasia, J. Price, E. Jeans
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引用次数: 0
Craniospinal Irradiation for Leptomeningeal Disease in Recurrent Breast Cancer 颅脊髓照射治疗复发性乳腺癌轻脑膜病
Pub Date : 2021-06-01 DOI: 10.37549/aro1276
J. Kwok, M. Yaraskavitch, J. Henning, D. Graham, N. Logie
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引用次数: 0
期刊
Applied radiation oncology
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