Blockchain technologies has been in the forefront of innovation and is maturing at a fast pace with fintech leading the way. Though the innovation in the permission less space is high, the enterprise adoption has still not caught up. The reasons include a variety of reasons including inadequate understanding of the technology, full awareness even in enterprises, unclear regulations, and lack of exploration and evangelism to really understand the reimagination of shared enterprise business processes. Most enterprise blockchain efforts are run from a small exploratory group in large companies and has NOT moved beyond pilots or limited production tryouts in to mainstream adoption at scale. This is because there is not much knowledge about what is possible for reimagining current business processes which are mostly unilateral. This is more obvious in healthcare. A horizontal transformation enabler like the blockchain technologycan effect collaborative business processes in a networked world.This paper explores the root causes for the challengesand suggests a methodology for discovery of the key inflection points for potential collaborative business processes and the re-engineering that would be needed. Blockchain in enterprise are not an isolated piece of technology, and has to interact with the enterprise assets, and there has to be mechanisms for aggregating the data that is meaningful to the counter parties for shared collaboration. Equally important is solid and a stair-stepping change management plan for the blockchain efforts to meet operations mainstream and gradually move the operations to the end state. Possibilities and results of the collaborative processes have to be shown in meticulous economic rigor for any possibilities of blockchain efforts getting the enterprise portfolio dollars against many enterprise systems that are already overloading budgets. The paper will cite the journey in a reference implementation with results, findings at the technical, functional, operational and change management levels for healthcare administration executives and portfolio managers.
{"title":"Moving Beyond POCs and Pilots to Mainstream: Discovery and Lessons from Blockchain in Healthcare","authors":"Sathya Krishnasamy, MS","doi":"10.30953/bhty.v6.280","DOIUrl":"https://doi.org/10.30953/bhty.v6.280","url":null,"abstract":"Blockchain technologies has been in the forefront of innovation and is maturing at a fast pace with fintech leading the way. Though the innovation in the permission less space is high, the enterprise adoption has still not caught up. The reasons include a variety of reasons including inadequate understanding of the technology, full awareness even in enterprises, unclear regulations, and lack of exploration and evangelism to really understand the reimagination of shared enterprise business processes. Most enterprise blockchain efforts are run from a small exploratory group in large companies and has NOT moved beyond pilots or limited production tryouts in to mainstream adoption at scale. This is because there is not much knowledge about what is possible for reimagining current business processes which are mostly unilateral. This is more obvious in healthcare. A horizontal transformation enabler like the blockchain technologycan effect collaborative business processes in a networked world.This paper explores the root causes for the challengesand suggests a methodology for discovery of the key inflection points for potential collaborative business processes and the re-engineering that would be needed. Blockchain in enterprise are not an isolated piece of technology, and has to interact with the enterprise assets, and there has to be mechanisms for aggregating the data that is meaningful to the counter parties for shared collaboration. Equally important is solid and a stair-stepping change management plan for the blockchain efforts to meet operations mainstream and gradually move the operations to the end state. Possibilities and results of the collaborative processes have to be shown in meticulous economic rigor for any possibilities of blockchain efforts getting the enterprise portfolio dollars against many enterprise systems that are already overloading budgets. The paper will cite the journey in a reference implementation with results, findings at the technical, functional, operational and change management levels for healthcare administration executives and portfolio managers.","PeriodicalId":72422,"journal":{"name":"Blockchain in healthcare today","volume":"10 4p2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139145333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Blockchain applications in healthcare have grown rapidly and it includes record keeping, clinical trials, medical supply chains, patient monitoring, etc. where Blockchain characteristics are needed to improve safety, privacy, and security. Blockchain Technology is one of the biggest disruptive technologies today. However, Porru, et. al (2017) have reported it lacks processes, tools, and techniques. Therefore, this paper provides a systematic framework for a secure and sustainable software engineering framework for healthcare blockchain applications. Secure and Sustainable Software Engineering Framework for Healthcare Blockchain Applications (S3EF-HBCA) significant contribution includes requirements engineering for healthcare, business process modelling for healthcare, domain modelling for healthcare, a reference architecture for healthcare, and validation by case study on Electronic Healthcare Record Management System (EHR), and simulation with Business Process Modelling Notation (BPMN) tools. The simulation shows it has taken 10.45 minutes to process 100 instances of real-time data and service requests. The overall result shows encouragement in terms of process, tools, standards, and testing.
{"title":"S3EF-HBCAs: Secure and Sustainable Software Engineering Framework for Healthcare Blockchain Applications","authors":"Muthu Ramachandran, PhD","doi":"10.30953/bhty.v6.286","DOIUrl":"https://doi.org/10.30953/bhty.v6.286","url":null,"abstract":"Blockchain applications in healthcare have grown rapidly and it includes record keeping, clinical trials, medical supply chains, patient monitoring, etc. where Blockchain characteristics are needed to improve safety, privacy, and security. Blockchain Technology is one of the biggest disruptive technologies today. However, Porru, et. al (2017) have reported it lacks processes, tools, and techniques. Therefore, this paper provides a systematic framework for a secure and sustainable software engineering framework for healthcare blockchain applications. Secure and Sustainable Software Engineering Framework for Healthcare Blockchain Applications (S3EF-HBCA) significant contribution includes requirements engineering for healthcare, business process modelling for healthcare, domain modelling for healthcare, a reference architecture for healthcare, and validation by case study on Electronic Healthcare Record Management System (EHR), and simulation with Business Process Modelling Notation (BPMN) tools. The simulation shows it has taken 10.45 minutes to process 100 instances of real-time data and service requests. The overall result shows encouragement in terms of process, tools, standards, and testing.","PeriodicalId":72422,"journal":{"name":"Blockchain in healthcare today","volume":"42 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139164738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aleksandr Kormiltsyn, V. Dwivedi, Chibuzor Udokwu, Alex Norta
Despite the great potential for healthcare professionals, individuals, and researchers, integrating healthcare information from personal health records (PHR) and electronic health records (EHR) systems is complicated because of structural- and semantic heterogeneity and -privacy. Healthcare data is an emotional issue because of fear of privacy violations. Blockchain technology enables a patient's data privacy, transparency, and immutability in cross-organizational processes where a patient regulates access to his data and is aware of its usage. At the same time, blockchain technology creates new challenges for e-healthcare systems, such as data privacy, observability, and online enforceability. In this paper, we propose a design and formalization of a secure blockchain-based, and patient-centric system with a definition of PHR requirements, an ontology for privacy-conflict resolution- and management mechanisms that takes into account the emotional aspects related to sharing sensitive healthcare records. Throughout this paper, we illustrate our ideas with a running case about preventive- and personalized healthcare.
{"title":"Privacy-Conflict Resolution for Integrating Personal- and Electronic Health Records in Blockchain-Based Systems","authors":"Aleksandr Kormiltsyn, V. Dwivedi, Chibuzor Udokwu, Alex Norta","doi":"10.30953/bhty.v6.276","DOIUrl":"https://doi.org/10.30953/bhty.v6.276","url":null,"abstract":"Despite the great potential for healthcare professionals, individuals, and researchers, integrating healthcare information from personal health records (PHR) and electronic health records (EHR) systems is complicated because of structural- and semantic heterogeneity and -privacy. Healthcare data is an emotional issue because of fear of privacy violations. Blockchain technology enables a patient's data privacy, transparency, and immutability in cross-organizational processes where a patient regulates access to his data and is aware of its usage. At the same time, blockchain technology creates new challenges for e-healthcare systems, such as data privacy, observability, and online enforceability. In this paper, we propose a design and formalization of a secure blockchain-based, and patient-centric system with a definition of PHR requirements, an ontology for privacy-conflict resolution- and management mechanisms that takes into account the emotional aspects related to sharing sensitive healthcare records. Throughout this paper, we illustrate our ideas with a running case about preventive- and personalized healthcare.","PeriodicalId":72422,"journal":{"name":"Blockchain in healthcare today","volume":"294 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138996840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Speakers discuss the importance of standardization in order to digitalize the U.S. pharmaceutical supply chain as motivated by the Drug Supply Chain Security Act (DSCSA). Key topics What is DSCSA? What does FDA’s Stabilization Period mean? Why do technology standards matter and how are they being implemented, i.e. interoperability through standards? Focus on standardization, due diligence in the context of DSCSA-regulated digitally managed pharma supply chain 2023 readiness in relation to stabilization period until 2024 Inspections will keep happening ATP is mandatory, authentication & authorization Data security
{"title":"Why Industry-Wide Standards Matter In Fulfilling the Intent of DSCSA","authors":"Christiane Wirrig, PhD, David Kessler","doi":"10.30953/bhty.v6.293","DOIUrl":"https://doi.org/10.30953/bhty.v6.293","url":null,"abstract":"Speakers discuss the importance of standardization in order to digitalize the U.S. pharmaceutical supply chain as motivated by the Drug Supply Chain Security Act (DSCSA). \u0000Key topics \u0000 \u0000What is DSCSA? \u0000What does FDA’s Stabilization Period mean? \u0000Why do technology standards matter and how are they being implemented, i.e. interoperability through standards? \u0000Focus on standardization, due diligence in the context of DSCSA-regulated digitally managed pharma supply chain \u00002023 readiness in relation to stabilization period until 2024 \u0000Inspections will keep happening \u0000ATP is mandatory, authentication & authorization \u0000Data security \u0000","PeriodicalId":72422,"journal":{"name":"Blockchain in healthcare today","volume":"44 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138605422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gianluca De Novi, PhD, Natalia Sofia, PharmD, Msc, Ingrid Vasiliu-Feltes MD EMBA, Christine, Yan Zang, PhD, Frank Ricotta
In an era characterized by the convergence of cutting-edge technologies, the world of healthcare and public health is on the brink of a profound transformation that will shape the future of medicine and wellness. This transformation is not merely an incremental step forward; it is a paradigm shift. It is driven by the synergistic integration of digital twins, blockchain technology, artificial intelligence (AI), and multi-omics platforms, collectively propelling us into uncharted territory. The integration of these innovations holds the potential to rewrite the rules of engagement in clinical trials, revamp the strategies for preventing public health crises, and redefine the way we manage, share, and secure healthcare data. As we embark on this journey of exploration and innovation, we find ourselves at a pivotal juncture, akin to the invention of the microscope in biology or the discovery of antibiotics in medicine. We are at the crossroads of a new era, one that teems with immense promise and transformative power.
{"title":"Blockchain Technology Predictions 2024: Transformations in Healthcare, Patient Identity and Public Health","authors":"Gianluca De Novi, PhD, Natalia Sofia, PharmD, Msc, Ingrid Vasiliu-Feltes MD EMBA, Christine, Yan Zang, PhD, Frank Ricotta","doi":"10.30953/bhty.v6.287","DOIUrl":"https://doi.org/10.30953/bhty.v6.287","url":null,"abstract":"In an era characterized by the convergence of cutting-edge technologies, the world of healthcare and public health is on the brink of a profound transformation that will shape the future of medicine and wellness. This transformation is not merely an incremental step forward; it is a paradigm shift. It is driven by the synergistic integration of digital twins, blockchain technology, artificial intelligence (AI), and multi-omics platforms, collectively propelling us into uncharted territory. The integration of these innovations holds the potential to rewrite the rules of engagement in clinical trials, revamp the strategies for preventing public health crises, and redefine the way we manage, share, and secure healthcare data. As we embark on this journey of exploration and innovation, we find ourselves at a pivotal juncture, akin to the invention of the microscope in biology or the discovery of antibiotics in medicine. We are at the crossroads of a new era, one that teems with immense promise and transformative power.","PeriodicalId":72422,"journal":{"name":"Blockchain in healthcare today","volume":"40 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139253836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Why are so many in healthcare mistaking a dirty crypto asset market with a technology that elevates healthcare administration, interoperability, recovers lost revenue, increases security, patient safety, and more in healthcare? We published one open access keynote on Blockchain in Healthcare Today (BHTY) journal addressing overcoming objections in the marketplace (click here for access). I don’t know who benefits more listening to it, service providers, or those that need help transforming their business? We already know using the "B" word is a detractor. Those experiencing success are approaching it from other angles. Pearl's are shared in the body of this review.
为什么如此多的医疗保健行业人士将肮脏的加密资产市场与提升医疗保健管理、互操作性、挽回损失收入、提高安全性和患者安全等方面的技术混为一谈？我们在《今日医疗保健区块链》（Blockchain in Healthcare Today，BHTY）杂志上发表了一篇开放获取的主题演讲，探讨如何克服市场上的反对意见（点击此处获取）。我不知道谁听了更受益，是服务提供商，还是那些需要帮助转型的企业？我们已经知道，使用 "B "字会让人望而却步。那些正在经历成功的人正从其他角度来看待这个问题。在本评论的正文中，我们将分享珍珠公司的成功经验。
{"title":"Highlights from Advancing the Business of Health with Blockchain and Frontier Tech at ConV2X Symposium 2023","authors":"Tory Cenaj","doi":"10.30953/bhty.v6.288","DOIUrl":"https://doi.org/10.30953/bhty.v6.288","url":null,"abstract":"Why are so many in healthcare mistaking a dirty crypto asset market with a technology that elevates healthcare administration, interoperability, recovers lost revenue, increases security, patient safety, and more in healthcare? We published one open access keynote on Blockchain in Healthcare Today (BHTY) journal addressing overcoming objections in the marketplace (click here for access). I don’t know who benefits more listening to it, service providers, or those that need help transforming their business? We already know using the \"B\" word is a detractor. Those experiencing success are approaching it from other angles. Pearl's are shared in the body of this review.","PeriodicalId":72422,"journal":{"name":"Blockchain in healthcare today","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139254433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ingrid Vasiliu-Feltes MB EMBA, Michael Mylrea, PhD, Christina Yan Zhang, PhD, Tyler Cohen Wood, CISSP, Brian Thornley, BSc
The convergence of digital twin technologies with precision health, pharmaceutical industry, and life sciences has garnered substantial recent attention. As we advance toward personalized medicine and precision health, the fusion of digital twin and blockchain technologies is poised to fundamentally enhance healthcare outcomes. This conference discussion highlighted pivotal drivers accelerating the adoption of digital twin-enabled blockchain solutions, encompassing the shift to a decentralized world wide web (Web 3.0), the establishment of a global interconnected health ecosystem, and the distinct advantages offered by converging frontier technologies in optimizing healthcare, pharmaceutical industry, and life sciences. Yet, the effective deployment of blockchain-powered digital twins in precision health necessitates robust cyber safety measures, proactive ethical frameworks, data validation, provenance assurance, streamlined supply chain management, and heightened interoperability. The proceedings underscored Blockchain-powered Digital Twins' pivotal role in reshaping health data management, security, sharing, ownership, and monetization, as well as in revolutionizing pharmaceutical supply chain management and novel drugs and therapeutics development within the precision health domain.
{"title":"Impact of Blockchain-Digital Twin Technology on Precision Health, Pharmaceutical Industry, and Life Sciences Conv2X 2023 Report","authors":"Ingrid Vasiliu-Feltes MB EMBA, Michael Mylrea, PhD, Christina Yan Zhang, PhD, Tyler Cohen Wood, CISSP, Brian Thornley, BSc","doi":"10.30953/bhty.v6.281","DOIUrl":"https://doi.org/10.30953/bhty.v6.281","url":null,"abstract":"The convergence of digital twin technologies with precision health, pharmaceutical industry, and life sciences has garnered substantial recent attention. As we advance toward personalized medicine and precision health, the fusion of digital twin and blockchain technologies is poised to fundamentally enhance healthcare outcomes. This conference discussion highlighted pivotal drivers accelerating the adoption of digital twin-enabled blockchain solutions, encompassing the shift to a decentralized world wide web (Web 3.0), the establishment of a global interconnected health ecosystem, and the distinct advantages offered by converging frontier technologies in optimizing healthcare, pharmaceutical industry, and life sciences. Yet, the effective deployment of blockchain-powered digital twins in precision health necessitates robust cyber safety measures, proactive ethical frameworks, data validation, provenance assurance, streamlined supply chain management, and heightened interoperability. The proceedings underscored Blockchain-powered Digital Twins' pivotal role in reshaping health data management, security, sharing, ownership, and monetization, as well as in revolutionizing pharmaceutical supply chain management and novel drugs and therapeutics development within the precision health domain.","PeriodicalId":72422,"journal":{"name":"Blockchain in healthcare today","volume":" 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135341442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
“To understand innovation you should ask "why not?" and not "why?" Selling (blockchain) is a problem and people and companies are blocking adoption which prevents innovation within a company, and stymies costs savings and efficientcy - that is the problem. It's a problem to be stuck in an innovation department - blockchain needs to be used in operations. Scientists and technologists need to understand one another better to create opportunity and success" - Raja Sharif, CEO, ATMPS In 2022, the team at ATMPS launched a potential game changer with a new approach to cell and gene therapy tracking, allowing more streamlined applications, payment options, and opportunity to realize true manufacturing safety and trust at scale, faster for personalized medicines and regimen treatments. The speaker highlights his experiences, and overcomes market challenges empasizing the need for better commercialization strategies for blockchain. In addition, the fllowing topics are addressed in the keynote: Automated Processes Regulatory Visibility & Compliance, FDA 21 CFR , HIPAA, GDPR Putting Together Blockchain Architecture for IRTS & ERH Integration Patient Apps and Mobile Device Issues Supply Chain
{"title":"Accelerating the Worldwide Adoption of Blockchain Technology","authors":"Raja Sharif","doi":"10.30953/bhty.v6.278","DOIUrl":"https://doi.org/10.30953/bhty.v6.278","url":null,"abstract":"“To understand innovation you should ask \"why not?\" and not \"why?\" Selling (blockchain) is a problem and people and companies are blocking adoption which prevents innovation within a company, and stymies costs savings and efficientcy - that is the problem. It's a problem to be stuck in an innovation department - blockchain needs to be used in operations. Scientists and technologists need to understand one another better to create opportunity and success\" - Raja Sharif, CEO, ATMPS \u0000In 2022, the team at ATMPS launched a potential game changer with a new approach to cell and gene therapy tracking, allowing more streamlined applications, payment options, and opportunity to realize true manufacturing safety and trust at scale, faster for personalized medicines and regimen treatments. The speaker highlights his experiences, and overcomes market challenges empasizing the need for better commercialization strategies for blockchain. In addition, the fllowing topics are addressed in the keynote: \u0000 \u0000Automated Processes \u0000Regulatory Visibility & Compliance, FDA 21 CFR , HIPAA, GDPR \u0000Putting Together Blockchain Architecture for IRTS & ERH Integration \u0000Patient Apps and Mobile Device Issues \u0000Supply Chain \u0000","PeriodicalId":72422,"journal":{"name":"Blockchain in healthcare today","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46069054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-31DOI: 10.55092/blockchain20230006
Zizheng Fonghu, Tsz Hon Yuen
{"title":"A critique on decentralized finance from a social, political, and economic perspective","authors":"Zizheng Fonghu, Tsz Hon Yuen","doi":"10.55092/blockchain20230006","DOIUrl":"https://doi.org/10.55092/blockchain20230006","url":null,"abstract":"","PeriodicalId":72422,"journal":{"name":"Blockchain in healthcare today","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75449913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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