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Measuring quality of recovery (QoR-15) after degenerative spinal surgery: A prospective observational study 测量脊柱退行性手术后的康复质量(QoR-15):前瞻性观察研究
Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102767
Marianne Dyrby Lorenzen , Casper Friis Pedersen , Leah Y. Carreon , Jane Clemensen , Mikkel O. Andersen

Introduction

The Quality of Recovery (QoR-15) score evaluates patient's recovery after surgery and anesthesia. There is a lack of studies focusing on the patients' quality of recovery in the early post-discharge phase after elective lumbar spine surgery.

Research question

We aimed to identify the QoR-15 score in patients who underwent surgery for degenerative low back conditions. Furthermore, we aimed to identify the individual items of the QoR-15 that are crucial for the patients’ quality of recovery.

Material and methods

The study was conducted at a spine center in Denmark from December 2021 to September 2022. Data were collected, using a mobile health application, preoperatively and at 3 time points after hospital discharge. Descriptive analysis followed by within-subjects longitudinal repeated measures was conducted. The individual items of the QoR-15 score were explored using a heatmap.

Results

Data from 46 patients were analysed. The mean QoR-15 sum score at baseline was 105.4 ± 18.3. The mean QoR-15 sum scores were 108.1 ± 19.2 on post-discharge day 1, 118.5 ± 17.4 on day 7, and 120.7 ± 20.9 on day 14. The mean QoR-15 score from day 1 to day 7 improved significantly. Eight of the 15 items influenced the overall QoR-15 score.

Discussion and conclusion

This study applied the QoR-15 score in lumbar spine surgery patients. We identified specific items from the QoR-15 scale that are crucial to improving patients’ recovery after hospital discharge. Further research is needed to identify specific needs in the post-discharge period in this group of patients.

导言恢复质量(QoR-15)评分评估患者手术和麻醉后的恢复情况。我们旨在确定腰背退行性疾病手术患者的 QoR-15 评分。此外,我们还旨在确定 QoR-15 中对患者康复质量至关重要的各个项目。材料和方法这项研究于 2021 年 12 月至 2022 年 9 月在丹麦的一家脊柱中心进行。使用移动医疗应用程序收集术前和出院后三个时间点的数据。研究先进行描述性分析,然后进行受试者内纵向重复测量。结果分析了 46 名患者的数据。基线时 QoR-15 的平均总分为 105.4 ± 18.3。出院后第 1 天的平均 QoR-15 总分为 108.1 ± 19.2,第 7 天为 118.5 ± 17.4,第 14 天为 120.7 ± 20.9。从第 1 天到第 7 天,QoR-15 的平均得分明显提高。在 15 个项目中,有 8 个项目影响了 QoR-15 的总分。我们从 QoR-15 量表中找出了对改善患者出院后康复至关重要的特定项目。还需要进一步研究,以确定这类患者出院后的具体需求。
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引用次数: 0
A propensity-matched study of patients with symptomatic lumbar spinal stenosis opting for surgery versus not 症状性腰椎管狭窄症患者选择手术与不选择手术的倾向匹配研究
Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102802
Casper Friis Pedersen , Søren Eiskjær , Mikkel Østerheden Andersen , Leah Yacat Carreon , Peter Doering

Introduction

Although most surgeons treating patients with lumbar spinal stenosis (LSS) believe that surgical treatment is superior to conservative measures, systematics reviews have concluded that no solid evidence support this.

Research question

To compare change at 1-year of walking ability, health-related quality of life, leg and back pain in patients with symptomatic LSS referred to a spine surgery clinic who opted for surgery and those who did not.

Material and methods

The study included 149 operated and 149 non-operated patients seen by spine surgeons and diagnosed with LSS. The non-operated patients were propensity-matched to a cohort retrieved from the Danish national spine registry. Matching was done on demographics and baseline outcome measures. The outcomes was walking improvement measured by item 4 of the Oswestry Disability Index, EQ-5D-3L, global assessment (GA) of back/leg pain, back and leg pain on the Visual Analogue Scale and the Short Form 36 transition item 2.

Results

Less than half of the non-operated reached MCID on EQ-5D-3L, VAS pain legs or VAS pain back where 2/3 of the operated did. The largest difference was VAS back pain where 27.5% of the non-operated reached an MCID of 12 points compared to 71.8% in the operated group.

Discussion and conclusion

Surgical treated patients improved better than non-operated on all outcome measures. However, further research is required to compare the effectiveness of surgical decompression with non-operative care for LSS patients.

引言尽管大多数治疗腰椎管狭窄症(LSS)患者的外科医生都认为手术治疗优于保守治疗,但系统学回顾得出的结论是没有确凿证据支持这一观点。研究问题比较转诊至脊柱外科诊所并选择手术治疗和未选择手术治疗的无症状 LSS 患者 1 年后在行走能力、健康相关生活质量、腿痛和背痛方面的变化。未接受手术的患者与从丹麦国家脊柱登记处检索到的队列进行了倾向匹配。在人口统计学和基线结果测量方面进行了匹配。结果不到一半的非手术患者在EQ-5D-3L、VAS腿部疼痛或VAS背部疼痛方面达到了MCID,而2/3的手术患者达到了MCID。差异最大的是 VAS 背痛,27.5% 的非手术组患者达到了 12 分的 MCID,而手术组为 71.8%。然而,还需要进一步的研究来比较手术减压和非手术治疗对 LSS 患者的效果。
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引用次数: 0
Surgical treatment for insular gliomas. A systematic review and meta-analysis on behalf of the EANS neuro-oncology section 岛状胶质瘤的手术治疗。代表 EANS 神经肿瘤学分会进行的系统回顾和荟萃分析
Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102828
Matthias Simon , Anne Hagemann , Sanjana Gajadin , Francesco Signorelli , Arnaud J.P.E. Vincent , for the EANS Neuro-oncology Section

Introduction

The appropriate surgical management of insular gliomas is controversial. Management strategies vary considerably between centers.

Research question

To provide robust resection, functional and epilepsy outcome figures, study growth patterns and tumor classification paradigms, analyze surgical approaches, mapping/monitoring strategies, surgery for insular glioblastoma, as well as molecular findings, and to identify open questions for future research.

Material and methods

On behalf of the EANS Neuro-oncology Section we performed a systematic review and meta-analysis (using a random-effects model) of the more current (2000–2023) literature in accordance with the PRISMA guidelines.

Results

The pooled postoperative motor and speech deficit rates were 6.8% and 3.6%. There was a 79.6% chance for postoperative epilepsy control. The postoperative KPI was 80–100 in 83.5% of cases. Functional monitoring/mapping paradigms (which may include awake craniotomies) seem mandatory. (Additional) awake surgery may result in slightly better functional but also worse resection outcomes. Transcortical approaches may carry a lesser rate of (motor) deficits than transsylvian surgeries.

Discussion and conclusions

This paper provides an inclusive overview and analysis of current surgical management of insular gliomas. Risks and complication rates in experienced centers do not necessarily compare unfavorably with the results of routine neuro-oncological procedures. Limitations of the current literature prominently include a lack of standardized outcome reporting. Questions and issues that warrant more attention include surgery for insular glioblastomas and how to classify the various growth patterns of insular gliomas.

导言岛状胶质瘤的适当手术治疗存在争议。研究问题提供可靠的切除、功能和癫痫结果数据,研究生长模式和肿瘤分类范例,分析手术方法、绘图/监测策略、岛状胶质母细胞瘤手术以及分子研究结果,并确定未来研究的开放性问题。材料与方法我们代表EANS神经肿瘤学分会,根据PRISMA指南对最新(2000-2023年)的文献进行了系统回顾和荟萃分析(使用随机效应模型)。术后癫痫控制率为 79.6%。83.5%的病例术后KPI为80-100。功能监测/绘图范例(可能包括清醒开颅手术)似乎是强制性的。(额外的)清醒手术可能会带来稍好的功能性结果,但也会导致更差的切除结果。经皮质手术的(运动)功能障碍发生率可能低于经颅骨手术。讨论与结论本文对目前岛叶胶质瘤的手术治疗进行了全面概述和分析。有经验的中心的风险和并发症发生率并不一定比常规神经肿瘤手术的结果差。目前文献的局限性主要包括缺乏标准化的结果报告。值得更多关注的问题包括岛状胶质母细胞瘤的手术治疗以及如何对岛状胶质瘤的各种生长模式进行分类。
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引用次数: 0
Are diagnoses of unruptured intracranial aneurysms associated with quality of life, psychological distress, health anxiety, or use of healthcare services in untreated individuals? A longitudinal, nested case-control study 未破裂颅内动脉瘤的诊断与未经治疗者的生活质量、心理困扰、健康焦虑或医疗服务的使用有关吗?一项纵向巢式病例对照研究
IF 1.9 Q3 CLINICAL NEUROLOGY Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102915

Introduction

Increasing imaging examination rates leads to a corresponding rise in the detection rates of unruptured intracranial aneurysms (UIAs). There is limited knowledge on how the detection of UIA affects health-related outcomes in untreated patients.

Research question

Is the diagnosis of UIA associated with psychosocial outcomes, healthcare services utilisation, or sick leave in untreated individuals?

Material and methods

Nested case-control study with 96 participants diagnosed with UIAs through magnetic resonance angiography (MRA) screening, not receiving preventive aneurysm obliteration. Comparisons were made with Control1 (192 participants with negative MRAs) and Control2 (192 individuals not MRA screened). Quality of life, psychological distress, and health anxiety were assessed using EQ-5D-5L including EQ VAS, Hopkins Symptom Checklist-10, and Whiteley Index-6, respectively. Healthcare service utilisation and sick leave was measured using registry data. Median follow-up was 32–55 months for the different outcomes.

Results

UIA were in general not associated with psychosocial outcomes, neither compared to pre-screening values nor to controls. The exemption was a lower mean EQ VAS score at follow-up for cases (76.7) versus Control1 (80.0), regression coefficient −3.87 (95% CI (−7.60, −0.14). Cases had significantly higher rates of radiology exams compared to controls, with 1.47 (95% CI 1.25, 1.74) exams per person-year versus 0.91 (C95% CI 0.75, 1.09) for Control1 and 0.95 (95% CI CI 0.79, 1.14) for Control2. No significant differences were observed in other psychosocial outcomes, healthcare services utilisation, or sick-leave.

Discussion and conclusions

The overall impact of untreated UIAs appears to be limited when assessed years after diagnosis.

导言成像检查率的提高导致未破裂颅内动脉瘤(UIA)的检出率也相应提高。材料和方法对 96 名通过磁共振血管造影(MRA)筛查确诊为未破裂颅内动脉瘤且未接受预防性动脉瘤阻塞治疗的患者进行嵌套病例对照研究。研究结果与对照组1(192名磁共振成像呈阴性的患者)和对照组2(192名未接受磁共振成像筛查的患者)进行了比较。生活质量、心理困扰和健康焦虑分别采用 EQ-5D-5L (包括 EQ VAS)、霍普金斯症状清单-10 和怀特利指数-6 进行评估。医疗服务利用率和病假情况通过登记数据进行测量。不同结果的中位随访时间为 32-55 个月。与对照组1(80.0)相比,病例(76.7)在随访时的平均 EQ VAS 得分较低,回归系数为 -3.87 (95% CI (-7.60, -0.14))。病例的放射检查率明显高于对照组,病例的放射检查率为 1.47(95% CI 1.25,1.74)人/年,而对照组 1 为 0.91(C95% CI 0.75,1.09)人/年,对照组 2 为 0.95(95% CI CI 0.79,1.14)人/年。在其他社会心理结果、医疗服务利用率或病假方面未观察到明显差异。讨论与结论在诊断多年后进行评估时,未经治疗的 UIA 的总体影响似乎有限。
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引用次数: 0
Assessing Fracture Force in Classic and Novel Vertebropexy Techniques under Simulated Flexion Loads 在模拟屈曲负荷下评估经典和新型椎弓根钉技术的骨折力
IF 1.9 Q3 CLINICAL NEUROLOGY Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102883
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引用次数: 0
Current state and future perspectives of spinal navigation and robotics - an AO Spine survey 脊柱导航和机器人技术的现状和未来展望 - AO 脊柱调查
IF 1.9 Q3 CLINICAL NEUROLOGY Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102894
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引用次数: 0
Prevalence and Techniques of endoscopic Spinal Surgery among accredited Training Centers in Switzerland 瑞士认可培训中心的脊柱内窥镜手术普及率和技术
IF 1.9 Q3 CLINICAL NEUROLOGY Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102891
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引用次数: 0
Anterior Column Reconstruction of the Thoracolumbar Spine with a Novel Modular Carbon-PEEK Vertebral Body Replacement Device: Single Center Retrospective Cohort Analysis of 28 Cases 使用新型模块化碳-PEEK椎体置换装置重建胸腰椎前柱:对28例病例的单中心回顾性队列分析
IF 1.9 Q3 CLINICAL NEUROLOGY Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102899
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引用次数: 0
Fusion Rate of Biphasic Calcium Phosphate with Needle-Shaped Submicron Topography in Interbody Lumbar Fusion with Various Surgical Approaches for Degenerative Disc Disease 采用不同手术方法进行腰椎间盘退行性病变椎体间融合术时,针状亚微米双相磷酸钙的融合率
IF 1.9 Q3 CLINICAL NEUROLOGY Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102897
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引用次数: 0
How to play with the tools: trans-odontoid drainage of spinal abscess in a multidisciplinary approach. Case report. 如何使用工具:采用多学科方法经蝶骨引流脊柱脓肿。病例报告。
IF 1.9 Q3 CLINICAL NEUROLOGY Pub Date : 2024-01-01 DOI: 10.1016/j.bas.2024.102898
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引用次数: 0
期刊
Brain & spine
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