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Hyperbolic metamaterials: fusing artificial structures to natural 2D materials 双曲超材料:将人工结构融合到自然二维材料中
Pub Date : 2022-01-10 DOI: 10.1186/s43593-021-00008-6
Dasol Lee, Sunae So, Guangwei Hu, Minkyung Kim, Trevon Badloe, Hanlyun Cho, Jaekyung Kim, Hongyoon Kim, C. Qiu, J. Rho
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引用次数: 129
Viral inactivation by light. 光灭活病毒。
Pub Date : 2022-01-01 Epub Date: 2022-09-26 DOI: 10.1186/s43593-022-00029-9
Mohammad Sadraeian, Le Zhang, Farzaneh Aavani, Esmaeil Biazar, Dayong Jin

Nowadays, viral infections are one of the greatest challenges for medical sciences and human society. While antiviral compounds and chemical inactivation remain inadequate, physical approaches based on irradiation provide new potentials for prevention and treatment of viral infections, without the risk of drug resistance and other unwanted side effects. Light across the electromagnetic spectrum can inactivate the virions using ionizing and non-ionizing radiations. This review highlights the anti-viral utility of radiant methods from the aspects of ionizing radiation, including high energy ultraviolet, gamma ray, X-ray, and neutron, and non-ionizing photo-inactivation, including lasers and blue light.

如今,病毒感染是医学和人类社会面临的最大挑战之一。虽然抗病毒化合物和化学灭活仍然不足,但基于辐射的物理方法为预防和治疗病毒感染提供了新的潜力,而没有耐药性和其他不必要的副作用的风险。电磁波谱上的光可以通过电离和非电离辐射使病毒粒子失活。这篇综述从电离辐射(包括高能紫外线、伽马射线、X射线和中子)和非电离光灭活(包括激光和蓝光)方面强调了辐射方法的抗病毒效用。
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引用次数: 14
Light-driven single-cell rotational adhesion frequency assay. 光驱动单细胞旋转粘附频率测定。
Pub Date : 2022-01-01 DOI: 10.1186/s43593-022-00020-4
Yaoran Liu, Hongru Ding, Jingang Li, Xin Lou, Mingcheng Yang, Yuebing Zheng

The interaction between cell surface receptors and extracellular ligands is highly related to many physiological processes in living systems. Many techniques have been developed to measure the ligand-receptor binding kinetics at the single-cell level. However, few techniques can measure the physiologically relevant shear binding affinity over a single cell in the clinical environment. Here, we develop a new optical technique, termed single-cell rotational adhesion frequency assay (scRAFA), that mimics in vivo cell adhesion to achieve label-free determination of both homogeneous and heterogeneous binding kinetics of targeted cells at the subcellular level. Moreover, the scRAFA is also applicable to analyze the binding affinities on a single cell in native human biofluids. With its superior performance and general applicability, scRAFA is expected to find applications in study of the spatial organization of cell surface receptors and diagnosis of infectious diseases.

Supplementary information: The online version contains supplementary material available at 10.1186/s43593-022-00020-4.

细胞表面受体与细胞外配体之间的相互作用与生命系统的许多生理过程密切相关。在单细胞水平上测量配体-受体结合动力学已经发展了许多技术。然而,很少有技术可以在临床环境中测量单个细胞的生理相关剪切结合亲和力。在这里,我们开发了一种新的光学技术,称为单细胞旋转粘附频率测定(scRAFA),该技术模拟体内细胞粘附,以在亚细胞水平上实现靶细胞均匀和非均匀结合动力学的无标记测定。此外,scRAFA也适用于分析人体天然生物体液中单细胞的结合亲和力。scRAFA具有优异的性能和广泛的适用性,有望在细胞表面受体的空间组织研究和传染病的诊断中得到应用。补充信息:在线版本包含补充资料,提供地址:10.1186/s43593-022-00020-4。
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引用次数: 14
Highly sensitive force measurements in an optically generated, harmonic hydrodynamic trap 光学产生的谐波流体动力学阱中的高灵敏度力测量
Pub Date : 2021-12-01 DOI: 10.1186/s43593-021-00007-7
I. Stoev, B. Seelbinder, E. Erben, N. Maghelli, M. Kreysing
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引用次数: 45
Phonon scattering and exciton localization: molding exciton flux in two dimensional disorder energy landscape 声子散射和激子局域化:二维无序能量景观中的激子通量
Pub Date : 2021-11-08 DOI: 10.1186/s43593-021-00006-8
P. Qi, Yang Luo, Beibei Shi, Wei Li, Donglin Liu, Liheng Zheng, Zhixin Liu, Yanglong Hou, Z. Fang
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引用次数: 40
Phyllotaxis-inspired nanosieves with multiplexed orbital angular momentum Phyllotasis启发的具有多重轨道角动量的纳米筛
Pub Date : 2021-09-05 DOI: 10.1186/s43593-021-00005-9
Zhongwei Jin, D. Janoschka, Junhong Deng, Lin Ge, P. Dreher, B. Frank, Guangwei Hu, Jincheng Ni, Yuanjie Yang, Jing Li, Changyuan Yu, D. Lei, Guixin Li, S. Xiao, S. Mei, H. Giessen, Frank Meyer zu Heringdorf, C. Qiu
{"title":"Phyllotaxis-inspired nanosieves with multiplexed orbital angular momentum","authors":"Zhongwei Jin, D. Janoschka, Junhong Deng, Lin Ge, P. Dreher, B. Frank, Guangwei Hu, Jincheng Ni, Yuanjie Yang, Jing Li, Changyuan Yu, D. Lei, Guixin Li, S. Xiao, S. Mei, H. Giessen, Frank Meyer zu Heringdorf, C. Qiu","doi":"10.1186/s43593-021-00005-9","DOIUrl":"https://doi.org/10.1186/s43593-021-00005-9","url":null,"abstract":"","PeriodicalId":72891,"journal":{"name":"eLight","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42707801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 91
Computational imaging without a computer: seeing through random diffusers at the speed of light 无需计算机的计算成像:以光速透过随机散射体
Pub Date : 2021-07-14 DOI: 10.1186/s43593-022-00012-4
Yilin Luo, Yifan Zhao, Jingxi Li, Ege Cetintas, Y. Rivenson, M. Jarrahi, Aydogan Ozcan
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引用次数: 63
Highlighting photonics: looking into the next decade 聚焦光子学:展望未来十年
Pub Date : 2021-06-08 DOI: 10.1186/s43593-021-00002-y
Zhigang Chen, M. Segev
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引用次数: 165
eLight: enlightening and exploring light 光:启发和探索光
Pub Date : 2021-06-08 DOI: 10.1186/S43593-020-00001-5
Aydogan Ozcan, C. Qiu
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引用次数: 1
Planar liquid crystal polarization optics for augmented reality and virtual reality: from fundamentals to applications 用于增强现实和虚拟现实的平面液晶偏振光学:从基础到应用
Pub Date : 2021-06-08 DOI: 10.1186/s43593-021-00003-x
J. Xiong, Shin‐Tson Wu
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引用次数: 102
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