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Longitudinal imaging studies in schizophrenia: the relationship between brain morphology and outcome measures. 精神分裂症的纵向成像研究:脑形态与结果测量之间的关系。
Pub Date : 2010-07-01
Marcella Bellani, Nicola Dusi, Paolo Brambilla

Imaging studies have tried to identify morphological outcome measures of schizophrenia in the last two decades. In particular, longitudinal studies have reported a correlation between larger ventricles, decreased prefrontal volumes and worse outcome. This would potentially allow to isolate subtypes of schizophrenia patients with a worse prognosis and more evident biological impairments, ultimately helping in designing specific rehabilitation interventions.

在过去的二十年里,影像学研究试图确定精神分裂症的形态学结果。特别是,纵向研究报告了脑室较大、前额叶体积减小和预后较差之间的相关性。这将有可能分离出预后较差和更明显的生物学损伤的精神分裂症患者亚型,最终有助于设计特定的康复干预措施。
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引用次数: 0
The process of producing a “NICE” guideline 制定“NICE”指南的过程
Pub Date : 2010-07-01 DOI: 10.1017/S1121189X00001135
D. Goldberg
SUMMARY This paper describes the process of preparing a Clinical Guideline for “NICE”, the National Institute for Health and Clinical Excellence in the United Kingdom. The procedure involves the group appointed to prepare the guideline relating to the various “stakeholders” who have an interest on the one hand, and satisfying the fairly demanding standards set by NICE on the other. The strengths and limitations of the approach based on evidence based medicine are discussed.
本文描述了为“NICE”(英国国家健康与临床卓越研究所)准备临床指南的过程。这个过程包括指定一个小组来准备与各种“利益相关者”有关的指导方针,这些利益相关者一方面有自己的利益,另一方面要满足NICE设定的相当苛刻的标准。讨论了循证医学方法的优势和局限性。
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引用次数: 1
Authors are not criminals and editors should not be policemen. 作者不是罪犯,编辑也不应该是警察。
Pub Date : 2010-07-01
Povl Munk Jorgensen

Authors are a necessary and most appreciated basis for the publishing of any scientific journal. They should be welcomed for their creativity, originality and productivity, not stigmatized in general as cheaters and criminals because a very few were tempted beyond their control to cut the slices a bit too thin, overdo the utilization of leftover data, listed too many authors to a paper, forgot to report a harmless study to an ethical committee, or in very few cases commit severe actions of fraud. The managerial way of thinking, meeting every author with systems of control and limitations is like poison to creative minds. Instead of appointing editors as policemen, we may preferably meet the vast majority of classical scholarly working scientists with trust, confidence and support, facilitating the process of disseminating the results from their creative minds--and of course consequently show the deliberately cheating researchers the door when they act unfaithfully to the scientific society.

作者是任何科学期刊出版的必要和最受赞赏的基础。他们应该因为他们的创造力、原创性和生产力而受到欢迎,而不是因为极少数人受到诱惑,超出了他们的控制,把切片切得太薄,过度利用剩余的数据,在一篇论文中列出太多的作者,忘记向伦理委员会报告无害的研究,或者在极少数情况下犯下严重的欺诈行为,而被普遍地污名为骗子和罪犯。管理式的思维方式,用控制和限制系统来对付每一个作者,就像毒药一样毒害了创造性的头脑。与其把编辑任命为警察,我们不如用信任、信心和支持来迎接绝大多数从事学术工作的经典科学家,促进他们创造性思维成果的传播过程——当然,这样一来,当那些故意作弊的研究人员对科学社会不忠实时,我们就会把他们拒之门外。
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引用次数: 0
How editors of psychiatric journals perceive their role? A follow-up appraisal seven years after. 精神病学期刊的编辑如何看待自己的角色?7年后的后续评估。
Pub Date : 2010-07-01
Michele Tansella
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引用次数: 0
The many lives of an (associate) editor. 一个(副)编辑的多重生活。
Pub Date : 2010-07-01
Carmine M Pariante

The role of editor of a journal attracts the vision of a scholar isolated in an ivory tower selecting "la crème" of the submitted papers, with no other preoccupations that the scientific rigour. This, is of course, only one of the many roles - or, as this editorial calls them, lives--of an editor. The essential skills are many and more complex, and an editor will encounter many problems that are related to such diverse issues as anticipating scientific trends, investigating misbehaviours, settling ethical disputes, and interfacing with the lay press. It is exciting and rewarding, and never predictable.

期刊编辑的角色吸引了一个被隔离在象牙塔里的学者的目光,他从提交的论文中选择“la cr”,除了科学的严谨性之外,没有其他的关注。当然,这只是编辑的众多角色之一——或者,就像这篇社论所说的那样,是活着的。编辑的基本技能很多,也更复杂,编辑会遇到许多问题,这些问题与各种各样的问题有关,比如预测科学趋势、调查不当行为、解决道德纠纷、与外行媒体打交道。这是令人兴奋和有益的,而且永远无法预测。
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引用次数: 0
Longitudinal imaging studies in schizophrenia: the relationship between brain morphology and outcome measures 精神分裂症的纵向成像研究:脑形态与结果测量之间的关系
Pub Date : 2010-07-01 DOI: 10.1017/S1121189X00001123
M. Bellani, N. Dusi, P. Brambilla
Abstract Imaging studies have tried to identify morphological outcome measures of schizophrenia in the last two decades. In particular, longitudinal studies have reported a correlation between larger ventricles, decreased prefrontal volumes and worse outcome. This would potentially allow to isolate subtypes of schizophrenia patients with a worse prognosis and more evident biological impairments, ultimately helping in designing specific rehabilitation interventions.
在过去的二十年里,影像学研究试图确定精神分裂症的形态学结果。特别是,纵向研究报告了脑室较大、前额叶体积减小和预后较差之间的相关性。这将有可能分离出预后较差和更明显的生物学损伤的精神分裂症患者亚型,最终有助于设计特定的康复干预措施。
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引用次数: 7
[Prevention of depression and suicide. Intervention program integrated with the involvement of general physicians]. 预防抑郁和自杀。综合了全科医生参与的干预方案]。
Pub Date : 2010-07-01
Carmine Munizza, Alessandro Coppo, Barbara D'Avanzo, Giulia Fantini, Luigi Ferrannini, Lucio Ghio, Raffaella Gonella, Roberto Keller, Paolo Peloso, Rocco Luigi Picci, Andrea Pierò, Luca Pinciaroli, Paola Rucci, Giuseppe Tibaldi, Marco Vaggi, Enrico Zanalda, Maria Zuccolin
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引用次数: 0
Primary care and the early phases of schizophrenia in the Czech Republic. 捷克共和国初级保健和精神分裂症的早期阶段。
Pub Date : 2010-07-01
David Holub, Barbora Wenigová, Daniel Umbricht, Andor E Simon

Aim: To explore knowledge, treatment setting, attitudes and needs associated with patients in early phases of psychosis among general practitioners (GPs) in Prague, and to compare results with GPs from 6 countries participating in the International GP Study (IGPS) on Early Psychosis (Canada, Australia, New Zealand, England, Norway, Austria).

Methods: Survey questionnaires were mailed to 648 GPs in the city of Prague.

Results: The response rate was 19.9%. Prague GPs showed significantly lower diagnostic knowledge of early phases of psychosis compared to their international colleagues. They frequently indicated depression/anxiety and somatic complaints as early warnings of psychosis. They more often considered their behaviour to be problematic and more commonly handed them over to specialists. The majority of Prague GPs wished specialized outpatient services for low-threshold referrals of such patients.

Conclusions: Along the mental health reforms in the Czech Republic which emphasis the role of primary care, GPs' knowledge of the early warning signs of psychosis needs to be improved.

目的:探讨布拉格全科医生(GP)与早期精神病患者相关的知识、治疗环境、态度和需求,并与参与早期精神病国际全科医生研究(IGPS)的6个国家(加拿大、澳大利亚、新西兰、英国、挪威、奥地利)的全科医生进行比较。方法:向布拉格648名全科医生邮寄调查问卷。结果:总有效率为19.9%。布拉格的全科医生对精神病早期阶段的诊断知识明显低于他们的国际同事。他们经常指出抑郁/焦虑和躯体症状是精神病的早期预警。他们通常认为自己的行为有问题,更常见的是将问题交给专家。布拉格的大多数全科医生希望为这类患者提供低门槛转诊的专门门诊服务。结论:随着捷克共和国精神卫生改革强调初级保健的作用,全科医生对精神病早期预警信号的认识有待提高。
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引用次数: 0
The economic impact of mental health stigma and discrimination: a systematic review. 精神卫生污名和歧视的经济影响:系统回顾。
Pub Date : 2010-07-01 DOI: 10.1017/s1121189x00001159
Jessica Sharac, Paul McCrone, Sarah Clement, Graham Thornicroft

Unlabelled: People with mental illness face stigma and discrimination in a variety of settings which can have an economic impact.

Aim: The aim of this paper was to identify literature on the economic impact of mental illness stigma.

Methods: A systematic review of the literature identified 30 papers from 27 studies by searching electronic databases and hand searching reference lists.

Results: Mental illness stigma/discrimination was found to impact negatively on employment, income, public views about resource allocation and healthcare costs.

Conclusions: Stigma and discrimination regarding mental health problems lead to adverse economic effects for people with these conditions. Interventions that reduce stigma may therefore also be economically beneficial.

无标签:精神疾病患者在各种环境中面临耻辱和歧视,这可能会产生经济影响。目的:本文的目的是确定文献对精神疾病污名的经济影响。方法:通过检索电子数据库和手工检索参考文献表的方法,对27项研究的30篇文献进行系统综述。结果:精神疾病污名/歧视对就业、收入、公众对资源配置和医疗费用的看法产生负面影响。结论:对心理健康问题的污名化和歧视会给这些疾病患者带来不利的经济影响。因此,减少耻辱感的干预措施也可能在经济上有益。
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引用次数: 198
The place of the British Journal of Psychiatry in the mental health league 《英国精神病学杂志》在精神健康领域的地位
Pub Date : 2010-07-01 DOI: 10.1017/S1121189X00001093
P. Tyrer
Abstract The British Journal of Psychiatry is an independent mainstream general psychiatric journal that competes reasonably well with others in the field. It does so by keeping a healthy balance between the demands of its readers, its contributors and the need for good science. It publishes an eclectic mix of original articles, reviews, editorials, reappraisals, comment, opinion and extras, the latter including poetry, short summaries, literature and psychiatry, and a touch of humour. These contributions are not always in keeping with the harsh requirements of the impact factor, but we judge that this makes for a better all-round journal that advances psychiatry in all its manifold aspects and is anything but dull.
《英国精神病学杂志》是一份独立的主流普通精神病学杂志,在该领域与其他杂志竞争相当好。它通过在读者、贡献者的需求和对优质科学的需求之间保持健康的平衡来做到这一点。它出版了各种各样的原创文章、评论、社论、重新评价、评论、观点和附加内容,后者包括诗歌、简短摘要、文学和精神病学,还有一点幽默。这些贡献并不总是符合影响因子的苛刻要求,但我们判断,这使得一本更好的全方位期刊在各个方面都在推进精神病学,一点也不乏味。
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引用次数: 2
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Epidemiologia e psichiatria sociale
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