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Patient characteristics, symptoms, and urodynamic parameters associated with detrusor contraction duration in women 患者特征、症状和与女性逼尿肌收缩持续时间相关的尿动力学参数
Pub Date : 2023-05-25 DOI: 10.3389/fruro.2023.1173506
Connie N. Wang, Albert S. Ha, D. Chung
Background There is a lack of understanding of the clinical significance of detrusor contraction duration (DCD) measured on urodynamic studies (UDS). We aimed to identify patient characteristics, presenting symptoms and urodynamic parameters associated with DCD in women. Methods Using a single-institution database of UDS (2015-2019), 405 female patients with measurable detrusor contractions were identified. Baseline characteristics, presenting symptoms and UDS parameters were analyzed. Bladder outlet obstruction (BOO) was characterized using the Blaivas-Groutz nomogram. Wilcox Rank Sum Tests were used for descriptive statistics, and a univariable generalized linear model conforming to a gamma distribution was used. Results Median age was 65 years (IQR 52-75), BMI was 27.5 kg/m2 (IQR 23.9-31.1) and DCD was 90 seconds (IQR 57-124). On univariable analysis, degenerative disc disease (β = -17.9, p = 0.02), pelvic radiation (β = -31.91, p = 0.04), and stress incontinence (β = -14.11, p = 0.03) were associated with reduced DCD. Black race was associated with longer DCD (β = 22.92, p = 0.01). Analysis of UDS parameters revealed a significant increase in DCD per unit increase of bladder capacity (β = 0.08, p<0.001), detrusor pressure (Pdet) at maximum flow (Qmax) (β = 0.96, p<0.001), and maximum Pdet (β = 1.2, p<0.001). In contrast, a significant decrease in DCD was noted per unit increase in Qmax (β = -1.43, p<0.001). Finally, mild (β = 34.4, p<0.001), moderate (β = 72.52, p<0.001), and severe (β = 64.6, p<0.001) BOO were all associated with increased DCD. Conclusions Median DCD in women is 90 seconds. Longer DCD is associated with greater degree of BOO, higher maximum Pdet, Pdet at Qmax, and bladder capacity. Disc disease, irradiation and stress incontinence are associated with reduced DCD. Further studies are needed to evaluate the predictive value of DCD in women.
背景尿动力学研究(UDS)测量逼尿肌收缩持续时间(DCD)的临床意义尚缺乏认识。我们的目的是确定与女性DCD相关的患者特征、表现症状和尿动力学参数。方法使用UDS单机构数据库(2015-2019年),识别出405例可测量的女性逼尿肌收缩患者。分析基线特征、表现症状和UDS参数。膀胱出口梗阻(BOO)采用Blaivas-Groutz图进行表征。描述性统计采用Wilcox秩和检验,采用符合伽马分布的单变量广义线性模型。结果中位年龄65岁(IQR 52 ~ 75), BMI为27.5 kg/m2 (IQR 23.9 ~ 31.1), DCD为90秒(IQR 57 ~ 124)。在单变量分析中,椎间盘退行性疾病(β = -17.9, p = 0.02)、盆腔放疗(β = -31.91, p = 0.04)和应激性尿失禁(β = -14.11, p = 0.03)与DCD降低相关。黑人与较长的DCD相关(β = 22.92, p = 0.01)。UDS参数分析显示,膀胱容量每单位增加的DCD (β = 0.08, p<0.001)、最大流量(Qmax)时逼尿肌压力(Pdet) (β = 0.96, p<0.001)和最大Pdet (β = 1.2, p<0.001)显著增加。相比之下,每单位Qmax增加,DCD显著降低(β = -1.43, p<0.001)。最后,轻度(β = 34.4, p<0.001)、中度(β = 72.52, p<0.001)和重度(β = 64.6, p<0.001) BOO均与DCD升高相关。结论女性的中位DCD为90秒。较长的DCD与更大程度的BOO、更高的最大Pdet、Qmax时的Pdet和膀胱容量相关。椎间盘疾病、辐照和应激性尿失禁与DCD降低有关。需要进一步的研究来评估DCD在女性中的预测价值。
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引用次数: 0
Controlled trial of decision support for men with early-stage prostate cancer: brief research report of effects on patient knowledge 早期前列腺癌症患者决策支持的对照试验:对患者知识影响的简要研究报告
Pub Date : 2023-05-17 DOI: 10.3389/fruro.2023.1127089
J. Belkora, J. Broering, J. Neuhaus, A. Zargham, Tia Weinberg, J. Witte, Stacey A. Kenfield, Erin L. Van Blarigan, M. Cooperberg, Peter R. Carroll, J. Chan
Introduction A single-arm pre-post pilot study in an academic setting found that pre-consultation decision support was associated with improved patient knowledge among men with early-stage prostate cancer. We now report on exploratory analyses from a controlled study featuring patients from both academic and community settings. Methods We enrolled 58 men to usual care and 61 men to the intervention. We evaluated whether the intervention was associated with patients answering key knowledge items correctly just before their urology visit. Results Just prior to the urology visit, 39/56 or 70% in the intervention group replied correctly to key knowledge items, compared to 31/55 or 56% in the usual care group (p=0.15). At baseline, the intervention group started with 42/60 or 70% correct and the usual care group started with 28/56 or 50% (p=0.03). This imbalance at baseline created a ceiling effect: more men in the usual care group had room to improve on their knowledge scores. Indeed, seven men moved from incorrect to correct in the usual care group, versus 5 in the intervention group; and five men in the intervention group moved from correct to incorrect versus 3 in the usual care group (p=0.44). Discussion In addition to small sample size, reasons for the null findings may include clustering of highly educated participants at the academic site combined with over-representation of academic site participants in the intervention group. We confirmed, from the pilot study, the feasibility of using pre-health student interns as health coaches. Future research should explore whether increasing adoption of telehealth will improve the feasibility of delivering pre-visit decision support in community settings.
引言一项在学术环境中进行的单臂先导前研究发现,早期前列腺癌症男性的咨询前决策支持与患者知识的提高有关。我们现在报道了一项对照研究的探索性分析,该研究以来自学术和社区环境的患者为对象。方法58名男性接受常规护理,61名男性接受干预。我们评估了干预措施是否与患者在泌尿外科就诊前正确回答关键知识项目有关。结果就在泌尿外科就诊前,干预组的39/56或70%对关键知识项目的回答正确,而常规护理组的31/55或56%(p=0.015),干预组从42/60或70%的正确率开始,常规护理组从28/56或50%开始(p=0.03)。基线时的这种不平衡产生了上限效应:常规护理组中更多的男性在知识得分上有提高的空间。事实上,在常规护理组中,有7名男性从错误变为正确,而在干预组中为5名;干预组中有5名男性从正确变为不正确,而常规护理组中有3名男性(p=0.44)。讨论除了样本量小之外,无效发现的原因可能包括学术网站上受过高等教育的参与者聚集,以及干预组中学术网站参与者的代表性过高。我们从试点研究中证实了使用健康前实习学生作为健康教练的可行性。未来的研究应该探索远程医疗的日益普及是否会提高在社区环境中提供就诊前决策支持的可行性。
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引用次数: 0
Editorial: Insights in male urology: 2021, volume 1 社论:洞察男性泌尿外科:2021,卷1
Pub Date : 2023-05-03 DOI: 10.3389/fruro.2023.1192753
G. Russo, A. Cocci, I. Sokolakis, A. Lo Giudice, M. G. Asmundo
COPYRIGHT © 2023 Russo, Cocci, Sokolakis, Lo Giudice and Asmundo. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. TYPE Editorial PUBLISHED 03 May 2023 DOI 10.3389/fruro.2023.1192753
版权所有©2023 Russo、Cocci、Sokolakis、Lo Giudice和Asmundo。这是一篇根据知识共享署名许可(CC BY)条款发布的开放获取文章。根据公认的学术惯例,允许在其他论坛上使用、分发或复制,前提是原作者和版权所有人得到认可,并引用本期刊上的原始出版物。不允许使用、分发或复制不符合这些条款的内容。TYPE编辑出版于2023年5月3日DOI 10.3389/frruro.2023.1192753
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引用次数: 0
Buccal mucosa for use in urethral reconstruction: evolution of use over the last 30 years 口腔黏膜用于尿道重建:近30年来使用的演变
Pub Date : 2023-05-02 DOI: 10.3389/fruro.2023.1138707
Jordan Foreman, A. Peterson, K. Krughoff
COPYRIGHT © 2023 Foreman, Peterson and Krughoff. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. TYPE Review PUBLISHED 02 May 2023 DOI 10.3389/fruro.2023.1138707
版权所有©2023 Foreman、Peterson和Krughoff。这是一篇根据知识共享署名许可(CC BY)条款发布的开放获取文章。根据公认的学术惯例,允许在其他论坛上使用、分发或复制,前提是原作者和版权所有人得到认可,并引用本期刊上的原始出版物。不允许使用、分发或复制不符合这些条款的内容。TYPE Review出版于2023年5月2日DOI 10.3389/frruro.2023.1138707
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引用次数: 0
Understanding ureteropelvic junction obstruction: how far have we come? 了解肾盂输尿管连接处梗阻:我们已经走了多远?
Pub Date : 2023-04-19 DOI: 10.3389/fruro.2023.1154740
C. Costigan, N. Rosenblum
Congenital anomalies of the urinary tract are a major cause of chronic kidney disease in both adults and children. Ureteropelvic junction obstruction, usually detected as urinary tract dilatation in utero, is one of the most common forms of CAKUT. As antenatal ultrasound technology advances and screening becomes more widespread, increasing numbers of infants with this UPJO will be detected. Management of these infants presents a clinical conundrum, as distinguishing mild benign cases from those who may develop severe renal impairment is challenging. Herein we propose that an understanding of normal developmental and pathological mechanisms involved in UPJO is important in the armamentarium for tackling this challenging condition.
先天性尿路异常是成人和儿童慢性肾脏疾病的主要原因。尿道-骨盆交界处梗阻,通常在子宫内被检测为尿路扩张,是CAKUT最常见的形式之一。随着产前超声技术的进步和筛查的普及,越来越多的婴儿会被发现患有这种UPJO。这些婴儿的管理是一个临床难题,因为区分轻度良性病例和可能发展为严重肾损伤的病例具有挑战性。在此,我们提出,了解UPJO的正常发育和病理机制对于解决这一具有挑战性的疾病至关重要。
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引用次数: 0
Endourological treatment of upper tract urinary disease in children 儿童上尿路疾病的腔内治疗
Pub Date : 2023-04-18 DOI: 10.3389/fruro.2023.1150795
Darren Ha, Kelly T. Harris, K. Rove
With advances in therapeutic interventions, endourology has become standard of care for the treatment of numerous diseases in the field of pediatric urology. However, there remains a lack of agreement and evidence on the optimal approaches and associated complications of endourological treatment of upper urinary tract conditions in children, namely ureteropelvic junction (UPJ) obstruction, primary obstructive megaureter, and nephrolithiasis. While pyeloplasty remains the first-line surgical treatment for pediatric UPJ obstruction, endoscopic retrograde balloon dilatation (ERBD) and endopyelotomy continue to gain traction as less invasive means of treating obstruction, particularly for failed repairs. Studies report success rates ranging from 76–100% although re-stenosis or need for revision surgery is not uncommon. Endourological options for the surgical management of primary obstructive megaureter include ERBD or endoureterotomy, rather than the open option of ureteroneocystotomy with or without tapering. Both have shown long-term success rates ranging from 70–90%, however, there is emerging evidence that these therapies may be associated with a risk of postoperative vesicoureteral reflux. Meanwhile, for stone disease, shock wave lithotripsy (SWL), flexible ureteroscopy (URS), and percutaneous nephrolithotomy (PCNL) are mainstays in the pediatric urologist’s armamentarium. Studies have shown that URS and PCNL have comparable stone-free rates, although PCNL can be associated with increased morbidity. Advancements in technology have led to the use of smaller access sheaths without compromising stone-free rates or increasing long-term complications. The use of mini-PCNL in the adult population holds great potential for use in our pediatric patients. The rise of endourology expertise and improved technology makes it an attractive option that could even be considered as a first-line option for the treatment of various urinary tract conditions. Nevertheless, there is a paucity of evidence on outcomes and complications following its use for treatment of upper urinary tract diseases in children. This review aims to summarize and present results of endourological treatments for pediatric UPJ obstruction, primary obstructive megaureter, and nephrolithiasis, as well as highlight advancements in the field of endourology that may increase its utilization in pediatric urology in the future.
随着治疗干预措施的进步,泌尿道已成为儿科泌尿外科领域许多疾病治疗的标准护理。然而,对于儿童上尿路疾病,即肾盂输尿管连接处(UPJ)梗阻、原发性梗阻计和肾结石,泌尿系统内治疗的最佳方法和相关并发症,仍然缺乏一致和证据。虽然肾盂成形术仍然是儿童UPJ梗阻的一线手术治疗,但内镜逆行球囊扩张(ERBD)和肾盂切开术作为治疗梗阻的微创手段继续受到关注,特别是对于修复失败的方法。研究报告的成功率为76-100%,尽管再狭窄或需要翻修手术并不罕见。原发性梗阻性输尿管梗阻性手术治疗的输尿管腔内选择包括ERBD或输尿管腔内切开术,而不是输尿管腔内切开术(有或没有变细)。两种方法的长期成功率都在70-90%之间,然而,有新的证据表明,这些疗法可能与术后膀胱输尿管反流的风险相关。同时,对于结石疾病,冲击波碎石术(SWL)、柔性输尿管镜(URS)和经皮肾镜取石术(PCNL)是儿科泌尿科医生的主要选择。研究表明URS和PCNL的无结石率相当,尽管PCNL可能与发病率增加有关。技术的进步导致使用更小的导管鞘,而不会影响无结石率或增加长期并发症。在成人人群中使用mini-PCNL在我们的儿科患者中具有很大的应用潜力。随着泌尿系统专业知识的增加和技术的改进,它成为一种有吸引力的选择,甚至可以被认为是治疗各种泌尿系统疾病的一线选择。然而,缺乏证据表明其用于治疗儿童上尿路疾病的结果和并发症。本文旨在总结和介绍泌尿道内腔治疗小儿UPJ梗阻、原发性梗阻性尿管计和肾结石的结果,并重点介绍泌尿道内腔治疗领域的进展,这些进展可能会增加泌尿道内腔在儿科泌尿外科的应用。
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引用次数: 0
Clinical outcomes of cryptozoospermic patients undergoing surgical sperm retrieval 隐精子症患者手术取精的临床结果
Pub Date : 2023-04-01 DOI: 10.3389/fruro.2023.1160122
Raneen Sawaid Kaiyal, R. Cannarella, Shinnosuke Kuroda, N. Parekh, S. Vij, S. Lundy
Introduction Cryptozoospermia is defined by the World Health Organization (WHO) as the presence of isolated sperm cell in the ejaculate only identified after an extended microscopic search or after being pelleted. Although the number of spermatozoa is usually sufficient for intracytoplasmic sperm injection (ICSI), ICSI fails due to poor sperm quality in some cases. Contention remains regarding whether testicular sperm offers any advantage in this unique situation. At our tertiary referral center, we will offer patients a surgical sperm retrieval via conventional or microdissection testicular sperm extraction (microTESE) for men with cryptozoospermia and failed ICSI, or where ejaculated specimens are immotile or insufficient for ICSI. In this study, we sought to describe our experience and evaluate the predictors of success in cryptozoospermic patients who had microTESE at our center. Methods We retrospectively reviewed our electronic medical records for all patients with cryptozoospermia who underwent microTESE between 2007- 2021 for failed ICSI with ejaculated sperm or sperm quality deemed to be of insufficient quality for ICSI (e.g., nonmotile sperm). We evaluated demographics, preoperative lab results, pathology results, sperm retrieval rate (SRR) and ICSI outcomes. Results 28 cryptozoospermic patients were identified. These patients underwent 37 unique microTESE. 22 of these men had failed previous ICSI treatment with ejaculated sperm, while the other 6 patients had ejaculated sperm with non-suitable quality for ICSI. None had genetic abnormalities. Successful retrieval of motile sperm suitable for ICSI was achieved in in 30 micro TESE procedures (SRR: 81.0%).14 out of 28 patients (50%) who underwent embryo transfer had positive pregnancy result, and 12/28 patients (42.8%) had successful live birth. The most common pathological pattern was hypospermatogenesis found in 65.3% (17/26). Fibrosis pathology was significantly higher in the negative pregnancy group. There were no postoperative complications noted. Disscussion The use of testicular sperm in cryptozoospermic men with failed prior ICSI using ejaculated sperm has a high rate of pregnancy and live birth. While still controversial, our results suggest that surgical sperm retrieval is a viable option for these men with minimal risk of complications.
引言隐精子症是由世界卫生组织(世界卫生组织)定义的,即精液中存在分离的精子细胞,只有在扩大显微镜搜索或造粒后才能确定。尽管精子数量通常足以进行卵浆内精子注射(ICSI),但在某些情况下,由于精子质量差,ICSI失败。关于睾丸精子在这种特殊情况下是否有任何优势,仍存在争议。在我们的三级转诊中心,我们将为患有隐精子症和ICSI失败的男性,或射精标本不动或不足以进行ICSI的男性,通过常规或显微切割睾丸精子提取(microTESE)为患者提供手术取精。在这项研究中,我们试图描述我们的经验,并评估在我们中心接受microTESE治疗的隐精子症患者的成功预测因素。方法我们回顾性审查了2007年至2021年间因射精精子或精子质量被认为不足以进行ICSI(例如,非运动精子)的ICSI失败而接受microTESE的所有隐精子症患者的电子医疗记录。我们评估了人口统计学、术前实验室结果、病理学结果、精子回收率(SRR)和ICSI结果。结果发现28例隐精子症患者。这些患者接受了37次独特的microTESE。其中22名男性之前的ICSI治疗失败,而其他6名患者的精液质量不适合ICSI。没有人有遗传异常。在30例微型TESE手术中成功回收了适合ICSI的活动精子(SRR:81.0%)。28例胚胎移植患者中有14例(50%)妊娠结果呈阳性,28例患者中有12例(42.8%)活产成功。最常见的病理模式是尿道下裂,发生率为65.3%(17/26)。阴性妊娠组的纤维化病理明显高于阴性妊娠组。没有发现术后并发症。讨论睾丸精子在既往ICSI失败的隐精子症男性中的使用具有较高的妊娠率和活产率。尽管仍有争议,但我们的研究结果表明,手术取精对这些并发症风险最小的男性来说是一种可行的选择。
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引用次数: 1
Editorial: Genitourinary (GU) oncology in low-to-middle income countries 社论:中低收入国家的泌尿生殖肿瘤
Pub Date : 2023-03-30 DOI: 10.3389/fruro.2023.1172370
M. Shahait, M. Alsyouf, I. Abu-Gheida, F. Maluf
COPYRIGHT © 2023 Shahait, Alsyouf, Abu-Gheida and Maluf. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. TYPE Editorial PUBLISHED 30 March 2023 DOI 10.3389/fruro.2023.1172370
版权所有©2023 Shahait, Alsyouf, Abu-Gheida和Maluf。这是一篇基于知识共享署名许可(CC BY)的开放获取文章。允许在其他论坛上使用、分发或复制,前提是要注明原作者和版权所有者,并根据公认的学术惯例引用本期刊的原始出版物。不遵守这些条款的使用、分发或复制是不被允许的。类型社论发表于2023年3月30日DOI 10.3389/ fruo .2023.1172370
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引用次数: 0
Whose responsibility is it to talk with children and young people about intersex/differences in sex development? Young people’s, caregivers’ and health professionals’ perspectives 与儿童和年轻人谈论双性人/性别发展差异是谁的责任?年轻人、护理人员和卫生专业人员的观点
Pub Date : 2023-03-29 DOI: 10.3389/fruro.2023.1089198
K. Roen, Tove Lundberg, P. Hegarty, L. Liao
Introduction Over the past two decades, there has been a shift from concealing diagnoses of sex development from impacted people to the broad principle of age-appropriate disclosure. This change is consistent with children’s rights and with general shifts towards giving children medical information and involving patients in medical decision-making. The present paper examines how health professionals, young people and caregivers with experience in this area talk about the process of telling children about a diagnosis relating to sex development. The focus is on (i) who is given the role of talking with children and young people about their medical condition and care in the context of a diagnosis relating to sex development and (ii) what strategies seem to work, and what dilemmas are encountered, in engaging children and young people in talk about their condition and healthcare. Method Qualitative semi-structured interviews were carried out with 32 health professionals, 28 caregivers and 12 young persons recruited in the UK and Sweden, and thematic analysis was undertaken. Results The analysis identifies strategies and dilemmas in communication and a widespread assumption that it is caregivers’ responsibility to talk with children/young people about the diagnosis. This assumption creates difficulties for all three parties. This paper raises concern about children/young people who, despite a more patient-centred care ethos, are nevertheless growing up with limited opportunities to learn to talk about intersex or differences in sex development with confidence. Discussion Learning to talk about this topic is one step towards shared decision-making in healthcare. A case is made for services to take clearer responsibility for developing a protocol for educating children and young people in ways that involve caregivers. Such a process would include relevant medical information as well as opportunities to explore preferred language and meaning and address concerns of living well with bodily differences.
引言在过去的二十年里,人们已经从隐瞒受影响人群的性发育诊断转向了适龄披露的广泛原则。这一变化符合儿童权利,也符合向儿童提供医疗信息和让患者参与医疗决策的总体转变。本文探讨了在这一领域有经验的卫生专业人员、年轻人和护理人员如何谈论向儿童讲述与性发展有关的诊断的过程。重点是(i)在与性发展相关的诊断背景下,谁被赋予与儿童和年轻人谈论他们的医疗状况和护理的角色,以及(ii)在让儿童和年轻人为他们的状况和医疗保健进行讨论时,哪些策略似乎有效,遇到了哪些困境。方法对英国和瑞典招募的32名卫生专业人员、28名护理人员和12名年轻人进行定性半结构化访谈,并进行专题分析。结果该分析确定了沟通中的策略和困境,以及一种普遍的假设,即照顾者有责任与儿童/年轻人谈论诊断。这种假设给三方都带来了困难。这篇论文引起了人们对儿童/年轻人的担忧,尽管他们的护理精神更加以患者为中心,但在成长过程中,学习自信地谈论双性人或性别发展差异的机会有限。讨论学会谈论这个话题是迈向医疗保健共享决策的一步。有理由要求服务部门承担更明确的责任,制定一项协议,以让照顾者参与的方式教育儿童和年轻人。这一过程将包括相关的医学信息,以及探索首选语言和含义的机会,并解决身体差异下的良好生活问题。
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引用次数: 0
Intermittent catheterization: A patient-centric approach is key to optimal management of neurogenic lower urinary tract dysfunction 间歇导尿:以患者为中心的方法是神经源性下尿路功能障碍最佳管理的关键
Pub Date : 2023-03-28 DOI: 10.3389/fruro.2023.1158260
A. Krassioukov, B. Welk, D. Vrijens, S. Islamoska, K. B. Barken, V. Keppenne, M. Wyndaele, M. Walter
The value of disposable, single-use catheters has come under scrutiny in recent years with a growing attention on environmental sustainability. Intermittent catheterization (IC) is a widely available and minimally invasive technique for management of lower urinary tract dysfunction. Effective IC for individuals with neurogenic lower urinary tract dysfunction can promote their independence and improve quality of life. Are there alternative options within IC that could minimize environmental impact without compromising the safety and effectiveness of single-use catheters? How does the future of IC look – environmentally friendly, biodegradable, disposable catheters may be complementary to certified reusable catheters? In the midst of this debate, it is important to emphasize that individuals have the right to choose the best evidence-based treatment available. Here we consider the current landscape for IC with a focus on chronic use in individuals with neurogenic lower urinary tract dysfunction.
近年来,随着人们对环境可持续性的日益关注,一次性导管的价值受到了密切关注。间歇导管插入术(IC)是一种广泛使用的微创技术,用于治疗下尿路功能障碍。神经源性下尿路功能障碍患者的有效IC可以促进其独立性,提高生活质量。IC中是否有其他选择,可以在不影响一次性导管安全性和有效性的情况下将环境影响降至最低?IC的未来看起来如何?环保、可生物降解的一次性导管可能是经认证的可重复使用导管的补充?在这场辩论中,重要的是要强调,个人有权选择最佳的循证治疗方法。在这里,我们考虑了IC的现状,重点是神经源性下尿路功能障碍患者的慢性使用。
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Frontiers in urology
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