Pub Date : 2021-06-01DOI: 10.1007/978-3-030-78710-3_23
Zhan-Qiu Liu, Nyasha G Maforo, Pierangelo Renella, Nancy Halnon, Holden H Wu, Daniel B Ennis
Cardiomyopathy is the leading cause of mortality in boys with Duchenne muscular dystrophy (DMD). Left ventricular (LV) peak mid-wall circumferential strain (Ecc) is a sensitive early biomarker for evaluating both the subtle and variable onset and the progression of cardiomyopathy in pediatric subjects with DMD. Cine Displacement Encoding with Stimulated Echoes (DENSE) has proven sensitive to changes in Ecc, but its reproducibility has not been reported in a pediatric cohort or a DMD cohort. The objective was to quantify the intra-observer repeatability, and intra-exam and inter-observer reproducibility of global and regional Ecc derived from cine DENSE in DMD patients (N = 10) and age-and sex-matched controls (N = 10). Global and regional Ecc measures were considered reproducible in the intra-exam, intra-observer, and inter-observer comparisons. Intra-observer repeatability was highest, followed by intra-exam reproducibility and then inter-observer reproducibility. The smallest detectable change in Ecc was 0.01 for the intra-observer comparison, which is below the previously reported yearly decrease of 0.013 ± 0.015 in Ecc in DMD patients.
{"title":"Reproducibility of Left Ventricular CINE DENSE Strain in Pediatric Subjects with Duchenne Muscular Dystrophy.","authors":"Zhan-Qiu Liu, Nyasha G Maforo, Pierangelo Renella, Nancy Halnon, Holden H Wu, Daniel B Ennis","doi":"10.1007/978-3-030-78710-3_23","DOIUrl":"https://doi.org/10.1007/978-3-030-78710-3_23","url":null,"abstract":"<p><p>Cardiomyopathy is the leading cause of mortality in boys with Duchenne muscular dystrophy (DMD). Left ventricular (LV) peak mid-wall circumferential strain (E<sub>cc</sub>) is a sensitive early biomarker for evaluating both the subtle and variable onset and the progression of cardiomyopathy in pediatric subjects with DMD. Cine Displacement Encoding with Stimulated Echoes (DENSE) has proven sensitive to changes in E<sub>cc</sub>, but its reproducibility has not been reported in a pediatric cohort or a DMD cohort. The <b>objective</b> was to quantify the intra-observer repeatability, and intra-exam and inter-observer reproducibility of global and regional E<sub>cc</sub> derived from cine DENSE in DMD patients (N = 10) and age-and sex-matched controls (N = 10). Global and regional E<sub>cc</sub> measures were considered reproducible in the intra-exam, intra-observer, and inter-observer comparisons. Intra-observer repeatability was highest, followed by intra-exam reproducibility and then inter-observer reproducibility. The smallest detectable change in E<sub>cc</sub> was 0.01 for the intra-observer comparison, which is below the previously reported yearly decrease of 0.013 ± 0.015 in E<sub>cc</sub> in DMD patients.</p>","PeriodicalId":73120,"journal":{"name":"Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH","volume":"12738 ","pages":"232-241"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10022706/pdf/nihms-1836552.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9149869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-06-01DOI: 10.1007/978-3-030-78710-3_25
Roshan Reddy Upendra, Brian Jamison Wentz, Richard Simon, Suzanne M Shontz, Cristian A Linte
Patient-specific left ventricle (LV) myocardial models have the potential to be used in a variety of clinical scenarios for improved diagnosis and treatment plans. Cine cardiac magnetic resonance (MR) imaging provides high resolution images to reconstruct patient-specific geometric models of the LV myocardium. With the advent of deep learning, accurate segmentation of cardiac chambers from cine cardiac MR images and unsupervised learning for image registration for cardiac motion estimation on a large number of image datasets is attainable. Here, we propose a deep leaning-based framework for the development of patient-specific geometric models of LV myocardium from cine cardiac MR images, using the Automated Cardiac Diagnosis Challenge (ACDC) dataset. We use the deformation field estimated from the VoxelMorph-based convolutional neural network (CNN) to propagate the isosurface mesh and volume mesh of the end-diastole (ED) frame to the subsequent frames of the cardiac cycle. We assess the CNN-based propagated models against segmented models at each cardiac phase, as well as models propagated using another traditional nonrigid image registration technique. Additionally, we generate dynamic LV myocardial volume meshes at all phases of the cardiac cycle using the log barrier-based mesh warping (LBWARP) method and compare them with the CNN-propagated volume meshes.
{"title":"CNN-Based Cardiac Motion Extraction to Generate Deformable Geometric Left Ventricle Myocardial Models from Cine MRI.","authors":"Roshan Reddy Upendra, Brian Jamison Wentz, Richard Simon, Suzanne M Shontz, Cristian A Linte","doi":"10.1007/978-3-030-78710-3_25","DOIUrl":"https://doi.org/10.1007/978-3-030-78710-3_25","url":null,"abstract":"<p><p>Patient-specific left ventricle (LV) myocardial models have the potential to be used in a variety of clinical scenarios for improved diagnosis and treatment plans. Cine cardiac magnetic resonance (MR) imaging provides high resolution images to reconstruct patient-specific geometric models of the LV myocardium. With the advent of deep learning, accurate segmentation of cardiac chambers from cine cardiac MR images and unsupervised learning for image registration for cardiac motion estimation on a large number of image datasets is attainable. Here, we propose a deep leaning-based framework for the development of patient-specific geometric models of LV myocardium from cine cardiac MR images, using the Automated Cardiac Diagnosis Challenge (ACDC) dataset. We use the deformation field estimated from the VoxelMorph-based convolutional neural network (CNN) to propagate the isosurface mesh and volume mesh of the end-diastole (ED) frame to the subsequent frames of the cardiac cycle. We assess the CNN-based propagated models against segmented models at each cardiac phase, as well as models propagated using another traditional nonrigid image registration technique. Additionally, we generate dynamic LV myocardial volume meshes at all phases of the cardiac cycle using the log barrier-based mesh warping (LBWARP) method and compare them with the CNN-propagated volume meshes.</p>","PeriodicalId":73120,"journal":{"name":"Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH","volume":"12738 ","pages":"253-263"},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10198131/pdf/nihms-1899917.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9864805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-26DOI: 10.1007/978-3-030-78710-3_6
Mengmeng Kuang, Yinzhe Wu, D. Alonso-'Alvarez, D. Firmin, J. Keegan, P. Gatehouse, Guang-Zhong Yang
{"title":"Three-Dimensional Embedded Attentive RNN (3D-EAR) Segmentor for Left Ventricle Delineation from Myocardial Velocity Mapping","authors":"Mengmeng Kuang, Yinzhe Wu, D. Alonso-'Alvarez, D. Firmin, J. Keegan, P. Gatehouse, Guang-Zhong Yang","doi":"10.1007/978-3-030-78710-3_6","DOIUrl":"https://doi.org/10.1007/978-3-030-78710-3_6","url":null,"abstract":"","PeriodicalId":73120,"journal":{"name":"Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH","volume":"1 1","pages":"55-62"},"PeriodicalIF":0.0,"publicationDate":"2021-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89284816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-04-12DOI: 10.1007/978-3-030-78710-3_11
Francesco Galati, Maria A. Zuluaga
{"title":"Efficient Model Monitoring for Quality Control in Cardiac Image Segmentation","authors":"Francesco Galati, Maria A. Zuluaga","doi":"10.1007/978-3-030-78710-3_11","DOIUrl":"https://doi.org/10.1007/978-3-030-78710-3_11","url":null,"abstract":"","PeriodicalId":73120,"journal":{"name":"Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH","volume":"7 1","pages":"101-111"},"PeriodicalIF":0.0,"publicationDate":"2021-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81132842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-25DOI: 10.1007/978-3-030-78710-3_55
Judith Zimmermann, Kathrin Baeumler, M. Loecher, T. Cork, Fikunwa O. Kolawole, Kyle Gifford, A. Marsden, D. Fleischmann, D. Ennis
{"title":"Quantitative Hemodynamics in Aortic Dissection: Comparing in Vitro MRI with FSI Simulation in a Compliant Model","authors":"Judith Zimmermann, Kathrin Baeumler, M. Loecher, T. Cork, Fikunwa O. Kolawole, Kyle Gifford, A. Marsden, D. Fleischmann, D. Ennis","doi":"10.1007/978-3-030-78710-3_55","DOIUrl":"https://doi.org/10.1007/978-3-030-78710-3_55","url":null,"abstract":"","PeriodicalId":73120,"journal":{"name":"Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH","volume":"239 1","pages":"575-586"},"PeriodicalIF":0.0,"publicationDate":"2021-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83486949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1007/978-3-030-78710-3_57
Jermiah J. Joseph, Ting-Yim Lee, D. Goldman, C. McIntyre, S. Kharche
{"title":"The Role of Extra-Coronary Vascular Conditions that Affect Coronary Fractional Flow Reserve Estimation","authors":"Jermiah J. Joseph, Ting-Yim Lee, D. Goldman, C. McIntyre, S. Kharche","doi":"10.1007/978-3-030-78710-3_57","DOIUrl":"https://doi.org/10.1007/978-3-030-78710-3_57","url":null,"abstract":"","PeriodicalId":73120,"journal":{"name":"Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH","volume":"27 1","pages":"595-604"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74698188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1007/978-3-030-78710-3_50
Narimane Gassa, N. Zemzemi, C. Corrado, Y. Coudière
{"title":"Spiral Waves Generation Using an Eikonal-Reaction Cardiac Electrophysiology Model","authors":"Narimane Gassa, N. Zemzemi, C. Corrado, Y. Coudière","doi":"10.1007/978-3-030-78710-3_50","DOIUrl":"https://doi.org/10.1007/978-3-030-78710-3_50","url":null,"abstract":"","PeriodicalId":73120,"journal":{"name":"Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH","volume":"96 1","pages":"523-530"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74974067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1007/978-3-030-78710-3_35
M. Gusseva, Joshua S. Greer, D. Castellanos, Mohamed Abdelghafar Hussein, G. Greil, S. Reddy, T. Hussain, D. Chapelle, R. Chabiniok
{"title":"Model-Assisted Time-Synchronization of Cardiac MR Image and Catheter Pressure Data","authors":"M. Gusseva, Joshua S. Greer, D. Castellanos, Mohamed Abdelghafar Hussein, G. Greil, S. Reddy, T. Hussain, D. Chapelle, R. Chabiniok","doi":"10.1007/978-3-030-78710-3_35","DOIUrl":"https://doi.org/10.1007/978-3-030-78710-3_35","url":null,"abstract":"","PeriodicalId":73120,"journal":{"name":"Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH","volume":"1 1","pages":"362-372"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83990401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1007/978-3-030-78710-3_33
L. Barbarotta, P. Bovendeerd
{"title":"Parameter Estimation in a Rule-Based Fiber Orientation Model from End Systolic Strains Using the Reduced Order Unscented Kalman Filter","authors":"L. Barbarotta, P. Bovendeerd","doi":"10.1007/978-3-030-78710-3_33","DOIUrl":"https://doi.org/10.1007/978-3-030-78710-3_33","url":null,"abstract":"","PeriodicalId":73120,"journal":{"name":"Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH","volume":"55 1","pages":"340-350"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84597242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.1007/978-3-030-78710-3_41
Hao Liu, Harshita Narang, R. Gorman, J. Gorman, M. Sacks
{"title":"On the Interrelationship Between Left Ventricle Infarction Geometry and Ischemic Mitral Regurgitation Grade","authors":"Hao Liu, Harshita Narang, R. Gorman, J. Gorman, M. Sacks","doi":"10.1007/978-3-030-78710-3_41","DOIUrl":"https://doi.org/10.1007/978-3-030-78710-3_41","url":null,"abstract":"","PeriodicalId":73120,"journal":{"name":"Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH","volume":"103 1","pages":"425-434"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76353282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}