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Are parental sociodemographic factors, oral health knowledge and practices linked to the oral health habits of their children with cleft lip and palate? 父母的社会人口因素、口腔健康知识和做法是否与唇腭裂儿童的口腔健康习惯有关?
IF 1.4 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-06-19 DOI: 10.2340/aos.v83.40938
Dilan Altun, Sevilay Karahan, Fatma Figen Özgür, Meryem Uzamış Tekçiçek, Melek Dilek Turgut

Objective: Children with cleft lip and palate (CLP) have a greater risk of dental caries. The parents' knowledge and attitudes may have an impact on their children's oral health and dietary habits. Therefore, the aim of this study was to assess the socio-demographic characteristics, oral health knowledge, oral health behaviours, and habits of the parents in addition to the relationship with the oral health and dietary practices of their children with CLP.

Material and methods: The parents of 343 patients with CLP participated in the study. An online questionnaire with 52 questions regarding sociodemographic characteristics, oral health and oral hygiene practices was presented to them.

Results: Parents with higher level of education had better oral health knowledge (p < 0.05). Logistic regression analysis showed that the factors affecting the child's tooth brushing habits were the mother's age (odds ratio [OR] = 1.071, 95% confidence interval [CI]: 1.062-1.153), the father's employment status (OR = 2.089, 95%CI: 1.065-4.097), and the mother's last dental visit (OR = 1.995, 95%CI: 1.119-3.557). The factors affecting the child's toothpaste usage were the mother's age (OR = 1.106, 95%CI: 1.030-1.114), the father's employment status (OR = 2.124, 95%CI: 1.036-4.354), and the mother's last dental visit (OR = 2.076, 95%CI: 1.137-3.79).

Conclusions: Parental factors have a significant influence on the oral health-related behaviours of children with CLP.

目的:唇腭裂儿童患龋齿的风险更大。家长的知识和态度可能会影响其子女的口腔健康和饮食习惯。因此,本研究旨在评估父母的社会人口学特征、口腔健康知识、口腔健康行为和习惯,以及与唇腭裂患儿口腔健康和饮食习惯的关系:343 名中耳炎患者的父母参加了研究。向他们发放了一份在线问卷,其中包含 52 个有关社会人口特征、口腔健康和口腔卫生习惯的问题:结果:受教育程度较高的家长对口腔健康知识的了解程度更高(P父母的因素对口颌畸形患儿的口腔健康相关行为有重要影响。
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引用次数: 0
Digital workflow feasibility for the fabrication of intraoral maxillofacial prosthetics after surgical resection: a systematic literature review. 手术切除后制作口内颌面修复体的数字化工作流程可行性:系统性文献综述。
IF 1.4 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-06-19 DOI: 10.2340/aos.v83.40870
Gunjan Srivastava, Subrat Kumar Padhiary, Neeta Mohanty, Pravinkumar G Patil, Saurav Panda, Carlos Cobo-Vazquez, Gülce Çakmak, Pedro Molinero-Mourelle

Objectives: To evaluate the current evidence of digital workflow feasibility based on the data acquisition methods and the software tools used to fabricate intraoral prostheses for patients with partial or total maxillary and mandibular defects.

Materials and methods: An electronic search was performed in PubMed, SCOPUS, and Web of Science using a combination of relevant keywords: digital workflow, digital designing, computer-assisted design-computer aided manufacturing, 3D printing, maxillectomy, and mandibulectomy. The Joanna Briggs Institute Critical Appraisal Tool was used to assess the quality of evidence in the studies reviewed.

Results: From a total of 542 references, 33 articles were selected, including 25 on maxillary prostheses and 8 on mandibular prostheses. The use of digital workflows was limited to one or two steps of the fabrication of the prostheses, and only four studies described a complete digital workflow. The most preferred method for data acquisition was intraoral scanning with or without a cone beam computed tomography combination.

Conclusion: Currently, the fabrication process of maxillofacial prostheses requires combining digital and conventional methods. Simplifying the data acquisition methods and providing user-friendly and affordable software may encourage clinicians to use the digital workflow more frequently for patients requiring maxillofacial prostheses.

目的根据为上下颌骨部分或全部缺损患者制作口内修复体所使用的数据采集方法和软件工具,评估当前数字化工作流程可行性的证据:在PubMed、SCOPUS和Web of Science中进行了电子搜索,使用了相关关键词:数字化工作流程、数字化设计、计算机辅助设计-计算机辅助制造、3D打印、上颌骨切除术和下颌骨切除术。乔安娜-布里格斯研究所(Joanna Briggs Institute)的 "批判性评估工具"(Critical Appraisal Tool)被用来评估所查阅研究的证据质量:从542篇参考文献中筛选出33篇文章,其中25篇涉及上颌假体,8篇涉及下颌假体。数字化工作流程的使用仅限于义齿制作的一个或两个步骤,只有四项研究描述了完整的数字化工作流程。最常用的数据采集方法是口内扫描,并结合或不结合锥形束计算机断层扫描:结论:目前,颌面修复体的制作过程需要结合数字化和传统方法。简化数据采集方法,提供用户友好且价格合理的软件,可以鼓励临床医生更频繁地使用数字化工作流程为需要颌面修复体的患者提供服务。
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引用次数: 0
Aesthetic assessment of maxillary lateral and canine implant-supported crowns by laypersons and orthodontists. 非专业人士和正畸医生对上颌侧冠和犬齿种植体支撑冠的美学评估。
IF 1.4 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-06-12 DOI: 10.2340/aos.v83.40738
Nina Sabel, Erika Toft, Erica Johansson, Julia Naoumova

Introduction: The objectives of this study were to evaluate how laypersons and orthodontists evaluate and rank aesthetic parameters of an implant-supported crown (ISC) on the canine position (ISC-C) and lateral position (ISC-L).

Methods: A digital survey of 11 cases, 5 ISC-C, 5 ISC-L and 1 control case without ISC, was distributed to 207 laypersons and 296 orthodontists. All cases included one extraoral photograph and three intraoral photographs. The respondents were asked to identify the ISC and to evaluate the aesthetic parameters regarding colour of the implant (CI), shape of the implant (SI) and gingival colour around ISC (GCI). Differences within and between the groups were tested using Chi-2-test and Independent-Samples t-test.

Results: All invited laypersons and 184 orthodontists (62% response rate) answered the survey. Orthodontists (89%) more correctly identified the ISC, regardless of its position, than laypersons (50%) (p < 0.001). Both laypersons (54%) and orthodontists (23%) rated higher proportions of acceptance of CI, SI and GCI in favour for the ISC-L than ISC-C (laypersons: 40%, orthodontists: 10%) (p < 0.001). Assessing each parameter separately, orthodontists rated higher for ISC-L, compared to the ISC-C (p < 0.001). In general, laypersons and orthodontist ranked tooth colour (mean, standard deviation [SD]:8.0,1.5 and 9.0, 1.0) and tooth shape (mean, SD: 8.0, 1.7 and 8.8, 1.2) as aesthetically higher than the gingival colour (mean, SD: 7.2, 2.2 and 8.0, 1.7) (p > 0.001).  Conclusion: Laypersons and orthodontists consider the ISC-L as aesthetically more preferable, compared to the ISC-C.

引言:本研究的目的是评估非专业人士和正畸医生如何评价种植体支持冠(ISC)在犬齿位置(ISC-C)和侧齿位置(ISC-L)上的美学参数并对其进行排序:向 207 名非专业人士和 296 名正畸医师分发了一份 11 个病例的数字调查表,其中包括 5 个 ISC-C、5 个 ISC-L 和 1 个无 ISC 的对照病例。所有病例均包括一张口外照片和三张口内照片。受访者被要求识别 ISC,并对种植体颜色(CI)、种植体形状(SI)和 ISC 周围牙龈颜色(GCI)等美学参数进行评估。采用Chi-2检验和独立样本t检验对组内和组间差异进行检验:所有受邀的非专业人士和 184 名正畸医生(62% 的回复率)都回答了调查。正畸医生(89%)比非专业人员(50%)更能正确识别 ISC(无论其位置如何)(p < 0.001)。非专业人士(54%)和口腔正畸医师(23%)对 CI、SI 和 GCI 的接受比例均认为 ISC-L 比 ISC-C 高(非专业人士:40%,口腔正畸医师:10%)(p < 0.001)。在对每个参数进行单独评估时,正畸医生对 ISC-L 的评分高于对 ISC-C 的评分(p < 0.001)。一般来说,非专业人士和正畸医生对牙齿颜色(平均值,标准差 [SD] :8.0,1.5 和 9.0,1.0)和牙齿形状(平均值,标准差:8.0,1.7 和 8.8,1.2)的美学评价高于牙龈颜色(平均值,标准差:7.2,2.2 和 8.0,1.7)(p > 0.001)。 结论:与 ISC-C 相比,非专业人士和正畸医生认为 ISC-L 在美学上更可取。
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引用次数: 0
The use of hyaluronic acid injection for treatment of black triangle and reconstruction of lost interdental papilla in anterior teeth: a systematic review. 使用透明质酸注射治疗前牙黑三角和重建缺失的牙间乳头:系统综述。
IF 1.4 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-06-12 DOI: 10.2340/aos.v83.40864
Shahad B Alsharif, Bushra Aljahdali

Objective: Non-surgical therapeutics to reconstruct lost interdental papilla are evolving; these include hyaluronic acid injection. The aim of this systematic review is to evaluate the efficacy, safety, and long-term outcomes of hyaluronic acid injection in the treatment of black triangles and reconstruction of lost interdental papilla in anterior teeth.

Materials and methods: The protocol was registered in PROSPERO (CRD42023446875) and in accordance with the Cochrane Handbook of Systematic Reviews of Interventions and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis 'PRISMA'. The search involved four databases, PubMed/MEDLINE, The Cochrane Library, Google Scholar, and ProQuest for ''grey literature' with additional manual search for studies published up to May 2024. Human clinical studies of a prospective nature (randomised clinical trials and prospective cohort studies) were included. Exclusion criteria were case reports, case series, review articles, letter to editor, personal opinion, and animal studies. Furthermore, studies which utilised hyaluronic acid injection in conjunction with other therapeutic material, tissue graft, or any surgical procedure were also excluded. The data were extracted independently by the two authors and incorporated after consensus. The risk of bias was assessed using the RoB2: the revised Cochrane risk of bias tool for randomised clinical trials and the Newcastle Ottawa scale for prospective cohort studies.

Results: 24 studies, 15 prospective clinical studies and nine randomised clinical trials, were included with a total of 898 interdental papillae injected with hyaluronic acid. The studies showed promising outcomes in the reconstruction of lost interdental papilla with minimal adverse reactions. Risk of bias assessment among prospective clinical studies revealed 13 good quality studies with only two poor studies while the randomised clinical trials consisted of three with low, one with some concern, and five studies with high risk of bias. However, due to the high heterogeneity, a meta-analysis was not feasible.  Conclusion: Hyaluronic acid injection is an effective minimally invasive approach in treating black triangles and reconstructing lost interdental papilla in the anterior teeth. Further long-term well-designed randomised clinical trials employing standardised procedures are essential to validate this treatment and provide better quality of evidence.

目的:重建牙间乳头缺失的非手术疗法正在不断发展,其中包括透明质酸注射。本系统综述旨在评估透明质酸注射治疗黑三角和重建前牙牙间乳头缺失的有效性、安全性和长期疗效:该研究方案已在 PROSPERO(CRD42023446875)上注册,并符合《科克伦干预措施系统综述手册》(Cochrane Handbook of Systematic Reviews of Interventions)和《系统综述和元分析首选报告项目》(Preferred Reporting Items for Systematic Reviews and Meta-Analysis,简称 "PRISMA")。检索涉及四个数据库:PubMed/MEDLINE、Cochrane 图书馆、Google Scholar 和 ProQuest 的 "灰色文献",并对 2024 年 5 月之前发表的研究进行了额外的人工检索。前瞻性人类临床研究(随机临床试验和前瞻性队列研究)均包括在内。排除标准包括病例报告、系列病例、综述文章、致编辑的信、个人观点和动物研究。此外,还排除了将透明质酸注射与其他治疗材料、组织移植或任何外科手术结合使用的研究。数据由两位作者独立提取,并在达成共识后纳入。结果:共纳入了 24 项研究,其中包括 15 项前瞻性临床研究和 9 项随机临床试验,共有 898 个牙间乳头注射了透明质酸。这些研究显示,在重建缺失的牙间乳头方面效果良好,不良反应极少。对前瞻性临床研究进行的偏倚风险评估显示,有13项研究质量良好,仅有2项研究质量较差,而随机临床试验中有3项研究偏倚风险较低,1项研究偏倚风险较高,5项研究偏倚风险较高。然而,由于异质性较高,因此无法进行荟萃分析。 结论透明质酸注射是治疗黑三角和重建前牙牙间乳头缺失的有效微创方法。要验证这种治疗方法并提供更高质量的证据,必须采用标准化程序,进一步开展设计良好的长期随机临床试验。
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引用次数: 0
The association of empathy and the work-family conflict in doctors of dental medicine. 牙科医生的同理心与工作和家庭冲突的关联。
IF 1.4 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-06-11 DOI: 10.2340/aos.v83.40852
Lidia Gavic, Antonija Jerkovic, Vesna Ambarkova, Daniel Jerkovic, Antonija Tadin

Objectives: Work-family conflict is a growing problem worldwide, because of changing work-family demographic trends and the spread of technology. Empathy, as the ability to understand and share the feelings of other people, is the essential component of emotional intelligence that plays a crucial role in healthcare settings. This study aimed to assess the level of emotional empathy and investigate its relationship with work-family role conflicts among dental medicine doctors.  Materials and methods: In this study participated 589 doctors of dental medicine from Croatia, Serbia, Bosnia and Herzegovina. The questionnaire included general and demographic data, the Emotional Empathy Scale questionnaire and the Work and Family Role Conflict Assessment Scale questionnaire.  Results: The research results indicate no significant association between empathy and conflict between work and family roles (R = 0.032, p = 0.435). Women have achieved significantly higher scores in Emotional Empathy Scale (p ≤ 0.001), while there was no difference in Work and Family Role Conflict Assessment Scale according to gender (p = 0.194). A difference in emotional empathy was observed depending on where the respondents were employed (p = 0.045) and depending on the specialisation of the dental medicine (p = 0.021).  Conclusion: Female doctors of dental medicine demonstrated higher emotional empathy while the work-family role conflict is experienced equally by both genders.

目的:由于工作-家庭人口趋势的变化和技术的普及,工作-家庭冲突是一个日益严重的全球性问题。移情是一种理解和分享他人感受的能力,是情商的重要组成部分,在医疗环境中起着至关重要的作用。本研究旨在评估牙科医生的情感共情水平,并调查其与工作-家庭角色冲突的关系。 材料和方法:来自克罗地亚、塞尔维亚、波斯尼亚和黑塞哥维那的 589 名牙科医生参与了这项研究。问卷包括一般和人口统计学数据、情感共鸣量表问卷和工作与家庭角色冲突评估量表问卷。 研究结果研究结果表明,移情与工作和家庭角色冲突之间没有明显联系(R = 0.032,p = 0.435)。女性在情感移情量表中的得分明显更高(p ≤ 0.001),而在工作与家庭角色冲突评估量表中没有性别差异(p = 0.194)。根据受访者的工作地点(p = 0.045)和牙科医学专业(p = 0.021)的不同,情感共鸣也存在差异。 结论牙科女医生表现出更高的情感共鸣,而两性在工作与家庭角色冲突方面的体验相同。
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引用次数: 0
A prospective study on maternal periodontal diseases and neonatal adverse outcomes. 孕产妇牙周病与新生儿不良预后的前瞻性研究。
IF 1.4 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-06-11 DOI: 10.2340/aos.v83.40836
Ping Wen, Huijun Li, Xiaoyi Xu, Feng Zhang, Dan Zhao, Rong Yu, Tianfan Cheng, Hao Wang, Chuanzhong Yang, Wei Qin, Xiuqiao Yang, Jilong Yao, Lijian Jin

Objective: It is evident that periodontitis is linked to various adverse pregnancy outcomes. This prospective study explored the potential link of maternal periodontal diseases to neonatal adverse outcomes.

Materials and methods: A total of 193 generally healthy females in their third trimester (34-36 weeks) of pregnancy were enrolled. All subjects received full-mouth periodontal assessment, and the periodontal inflamed surface area (PISA) was calculated. Demographic data, lifestyles and anthropometric measurements of the neonates (e.g., body length and head circumference) were recorded. Herein, small-for-gestational age (SGA) referred to gender- and age-adjusted birth weight below the 10th percentile in line with the standard reference. Multivariable logistic regression analysis and restricted cubic spline were performed for examining the association of periodontal parameters with SGA.  Results: There were 8.3% (16/193) of neonates with SGA. Significantly positive correlation existed between the percentage of tooth sites with increased probing depth and an elevated risk of SGA (OR: 1.052; P < 0.05). Yet, the PISA was positively associated with the risk of SGA (OR: 1.002; P < 0.05) as well. No significant link occurred between maternal periodontal status and other neonatal outcome measures.

Conclusion: Within the limitations of this study, the findings suggest that there could be a link between maternal periodontal diseases and neonatal adverse outcomes like SGA. Further investigation is required to clarify the current findings and potential implications for promoting maternal oral/periodontal health and newborn health.

目的:牙周炎显然与各种不良妊娠结局有关。这项前瞻性研究探讨了孕产妇牙周疾病与新生儿不良结局之间的潜在联系:共招募了 193 名怀孕三个月(34-36 周)的一般健康女性。所有受试者均接受了全口牙周评估,并计算了牙周炎症表面积(PISA)。此外,还记录了新生儿的人口统计学数据、生活方式和人体测量数据(如身长和头围)。在此,小于妊娠年龄(SGA)指的是根据性别和年龄调整后的出生体重低于标准参考值的第 10 百分位数。为了研究牙周参数与 SGA 的关系,我们进行了多变量逻辑回归分析和限制性三次样条分析。 结果显示8.3%(16/193)的新生儿患有 SGA。探诊深度增加的牙齿部位百分比与 SGA 风险升高之间存在显著正相关(OR:1.052;P < 0.05)。然而,PISA 也与 SGA 风险呈正相关(OR:1.002;P <0.05)。产妇牙周状况与其他新生儿结局指标之间没有明显联系:在本研究的局限性范围内,研究结果表明,产妇牙周疾病与新生儿不良结局(如 SGA)之间可能存在联系。需要进一步调查,以澄清目前的研究结果以及对促进孕产妇口腔/牙周健康和新生儿健康的潜在影响。
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引用次数: 0
Temporomandibular disorder and somatic symptoms: Relations to 'fear of missing out' and other negative emotional states. 颞下颌关节紊乱与躯体症状:与 "害怕错过 "和其他负面情绪状态的关系。
IF 1.4 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-28 DOI: 10.2340/aos.v83.40776
Adrian Ujin Yap, Florencia Kurniawan, Yenny Pragustine, Carolina Marpaung

Objective: The association between the 'fear of missing out (FOMO)' and physical symptoms has not been widely explored. This study aimed to investigate the relationship between FOMO and other negative emotions with Temporomandibular disorder (TMD) and somatic symptoms in young adults. The correlations between the various physical and emotional variables were also established.

Material and methods: TMD and somatic symptoms were appraised with the Short-form Fonseca Anamnestic Index, quintessential five TMD symptoms of the Diagnostic Criteria (DC)/TMD, and Patient Health Questionnaire-15. FOMO and other negative emotional states were assessed with the FOMO Scale and Depression, Anxiety, Stress Scales-21 (DASS-21). Data were evaluated using non-parametric tests/correlation and regression analysis (α = 0.05).

Results: While only negative affectivity (total DASS), anxiety, and stress differed significantly between those without and with TMDs, significant variances in FOMO and all DASS-21 constructs were discerned between individuals without and with somatization.  Conclusions: Individuals with orofacial pain and more severe somatic symptoms have higher levels of negative emotions including FOMO. While somatization increased the prospect of TMDs, being female, presence of TMDs, and negative affectivity were risk factors for somatization in young adults.

Clinical relevance: Asian young adults appear to be disposed to somatization, and TMDs may be a form of functional somatic syndromes. Recognition of somatic symptoms and emotional distress, including FOMO, is essential for person-centric TMD care.

目的:害怕错过(FOMO)"与躯体症状之间的关系尚未得到广泛探讨。本研究旨在调查 FOMO 及其他负面情绪与颞下颌关节紊乱 (TMD) 和年轻成年人躯体症状之间的关系。材料与方法:用短式丰塞卡躯体症状指数、诊断标准(DC)/颞下颌关节病的五种典型颞下颌关节病症状和患者健康问卷-15对颞下颌关节病和躯体症状进行评估。FOMO 量表和抑郁、焦虑、压力量表-21(DASS-21)评估了 FOMO 和其他负面情绪状态。数据使用非参数检验/相关性和回归分析(α = 0.05)进行评估:结果:虽然只有负性情感(DASS 总分)、焦虑和压力在无 TMD 和有 TMD 的人之间存在显著差异,但在无躯体化和有躯体化的人之间,FOMO 和所有 DASS-21 结构都存在显著差异。 结论有口面部疼痛和更严重躯体症状的人具有更高水平的负面情绪,包括 FOMO。虽然躯体化增加了TMD的可能性,但女性、TMD的存在和消极情绪是年轻人躯体化的风险因素:临床相关性:亚裔青壮年似乎具有躯体化倾向,而 TMD 可能是功能性躯体综合征的一种形式。识别躯体症状和情绪困扰(包括 FOMO)对于以人为本的 TMD 护理至关重要。
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引用次数: 0
Complications and complaints in craniofacial fractures - Finnish national data for 20 years. 颅颌面骨折的并发症和主诉--芬兰全国20年来的数据。
IF 1.4 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-28 DOI: 10.2340/aos.v83.40570
Inka Luotamo, Johanna Snäll, Miika Toivari

Objective: Research on reasons for malpractice claims in oral and maxillofacial surgery is scarce. The aim of this study was to investigate the causes and prevalence of permanent harm among craniofacial fracture related malpractice claims.

Materials and methods: A retrospective register study was designed and implemented. All patients with a complaint and a diagnosis of facial or cranial fracture were included. The main outcome was the presence of permanent harm, and the predictor variable was the cause of complaint. Chi-square test was used for estimation of statistical significance.

Results: Delay in correct diagnosis was the leading cause of malpractice claims (63.2%), and permanent harm was found in 23.1% of the population. 82.4% of injuries were facial fractures in total population. 65.3% (n = 98) of facial trauma were related with delayed diagnostics (p < 0.001). Permanent harm was more frequent in patients with delayed diagnosis (71.4%) than those without (60.7%, p = 0.299).

Conclusions: Claims of craniofacial trauma are related with under-diagnostics, and un-diagnosed facial fracture can lead to a high rate of permanent harm. Systematic clinical evaluation and facial trauma specialist consultation is recommended to set early correct diagnosis for and improve treatment of craniofacial trauma patients.

目的:有关口腔颌面外科医疗事故索赔原因的研究很少。本研究旨在调查颅颌面骨折相关不当索赔中永久性伤害的原因和发生率:设计并实施了一项回顾性登记研究。所有主诉并诊断为面部或颅骨骨折的患者均被纳入研究范围。主要结果是是否存在永久性伤害,预测变量是主诉原因。统计显著性采用卡方检验:结果:延误正确诊断是渎职索赔的主要原因(63.2%),23.1%的人受到永久性伤害。82.4%的受伤者面部骨折。65.3%(98人)的面部创伤与延误诊断有关(P < 0.001)。延误诊断的患者(71.4%)比未延误诊断的患者(60.7%,P = 0.299)更容易受到永久性伤害:结论:颅面部外伤的索赔与诊断不足有关,未确诊的面部骨折可导致高比例的永久性伤害。建议进行系统的临床评估和面部创伤专家会诊,以尽早对颅面创伤患者做出正确诊断并改善治疗。
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引用次数: 0
Examination of cytotoxic and antimicrobial effect of whitening toothpastes: an in vitro study. 检测美白牙膏的细胞毒性和抗菌效果:一项体外研究。
IF 1.4 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-27 DOI: 10.2340/aos.v83.40774
Numan Aydın, Aysun Kılıç Süloğlu, Neslihan İdil, Selen Öztürk, Serpil Karaoğlanoğlu

Objective: Toothpastes are widely used to protect oral and teeth health. This study aims to examine the cytotoxic and antimicrobial effects of whitening toothpastes.

Methods: In this study, extracts were prepared according to ISO 10993-12:2021 standard (0.2 g/mL) using whitening and conventional toothpastes. The prepared extracts were added to human gingival fibroblast cell lines (HGF-1) in different dilutions (1:1, 1:2, 1:4, 1:8, 1:16, and 1:32) and a cytotoxicity test was performed. Antimicrobial analysis of toothpastes was performed on Streptococcus mutans, Staphylococcus aureus, and Candida albicans using the hole-plate diffusion method. Cell viability and microbial analysis data were examined using two-way analysis of variance (ANOVA) and Tukey post-hoc test (p < 0.05).

Results: Toothpastes with sodium lauryl sulfate (SLS) in their composition showed statistically more toxic effects (p < 0.05). The activated carbon toothpastes without SLS showed over 90% cell viability after dilution. Although the dilution rate of toothpastes containing SLS increased, cell viability remained below 70%. All toothpastes used in the study showed antimicrobial effects on S. mutans, S. aureus, and C. albicans. Toothpaste containing hydrogen peroxide and SLS produced more antibacterial effects than activated carbon, blue covarine, microparticles, and conventional toothpaste.

Conclusions: SLS-containing toothpastes showed more toxicity on HGF-1 cells. Toothpaste containing hydroxyapatite did not show toxic effects on HGF-1 cells. SLS, sodium lauryl sarcosinate and hydrogen peroxide in toothpastes increase antimicrobial effects.

目的牙膏被广泛用于保护口腔和牙齿健康。本研究旨在探讨美白牙膏的细胞毒性和抗菌作用:本研究根据 ISO 10993-12:2021 标准(0.2 克/毫升),使用美白牙膏和传统牙膏制备提取物。将制备好的提取物以不同的稀释度(1:1、1:2、1:4、1:8、1:16 和 1:32)添加到人牙龈成纤维细胞系(HGF-1)中,并进行细胞毒性测试。使用孔板扩散法对牙膏中的变异链球菌、金黄色葡萄球菌和白色念珠菌进行了抗菌分析。细胞活力和微生物分析数据采用双向方差分析(ANOVA)和Tukey事后检验(P < 0.05)进行检验:结果:从统计学角度看,含有十二烷基硫酸钠(SLS)的牙膏毒性更强(p < 0.05)。不含 SLS 的活性炭牙膏在稀释后的细胞存活率超过 90%。虽然含有 SLS 的牙膏稀释率增加,但细胞存活率仍低于 70%。研究中使用的所有牙膏都对突变菌、金黄色葡萄球菌和白喉杆菌有抗菌作用。含有过氧化氢和 SLS 的牙膏比活性炭、蓝花楹、微颗粒和传统牙膏产生更多的抗菌效果:结论:含 SLS 的牙膏对 HGF-1 细胞的毒性更大。结论:含 SLS 的牙膏对 HGF-1 细胞的毒性更大,而含羟基磷灰石的牙膏对 HGF-1 细胞没有毒性作用。牙膏中的 SLS、十二烷基肌氨酸钠和过氧化氢会增加抗菌效果。
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引用次数: 0
Use of oral health care services by family caregivers and care recipients: the LENTO intervention. 家庭护理者和护理对象使用口腔保健服务的情况:LENTO 干预。
IF 1.4 4区 医学 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-22 DOI: 10.2340/aos.v83.40687
Shanza Razzaq, Irma Nykänen, Tarja Välimäki, Sohvi Koponen, Roosa-Maria Savela, Ursula Schwab, Anna Liisa Suominen

Objective: We aimed to evaluate the impact of an individually tailored preventive oral health intervention on the use of oral health care services by older family caregivers (FCs) and their care recipients (CRs).

Material and methods: A randomized controlled six and 12-month oral health intervention study included FCs and CRs aged ≥65 years living in Eastern Finland. The participants were randomly assigned to an intervention (FCs n = 53, CRs n = 47) and a control (FCs n = 39, CRs n = 35) group. Individually tailored oral health interventions for the FCs provided by a dental hygienist focused on oral hygiene and self-care. Generalized estimating equations were used to analyze the impact of intervention on the change in the use of oral health care services.

Results: The intervention had no significant effect on the use of oral health care services by the FCs or their CRs. Traditional factors such as female gender, a higher number of teeth, toothache, no dental fear, and higher morbidity were significantly (p < 0.05) associated with an increased use of oral health care services in the FCs, but not among the CRs.

Conclusions: Individually tailored preventive oral health intervention showed no effect on the use of oral health care services. To promote oral health among the elderly, specific interventions focusing on use of oral health care services are needed.

Trial registration: clinicaltrials.gov/study/NCT04003493.

目的我们的目的是评估个体定制的预防性口腔健康干预对老年家庭照顾者(FCs)及其照顾对象(CRs)使用口腔保健服务的影响:一项为期 6 个月和 12 个月的随机对照口腔健康干预研究纳入了居住在芬兰东部、年龄≥ 65 岁的家庭照顾者和受照顾者。参与者被随机分配到干预组(FCs n = 53,CRs n = 47)和对照组(FCs n = 39,CRs n = 35)。由一名牙科保健师为功能性口腔疾病患者提供量身定制的口腔健康干预,重点是口腔卫生和自我护理。采用广义估计方程分析干预对口腔保健服务使用变化的影响:结果:干预措施对功能界别及其会员使用口腔保健服务的情况没有明显影响。女性性别、牙齿数量较多、牙痛、无牙科恐惧和发病率较高等传统因素与功能界别口腔保健服务使用率的增加有明显相关性(P < 0.05),但与社区康复服务使用率的增加无明显相关性:个人定制的预防性口腔保健干预对口腔保健服务的使用没有影响。为了促进老年人的口腔健康,需要采取以使用口腔保健服务为重点的具体干预措施。试验注册:clinicaltrials.gov/study/NCT04003493。
{"title":"Use of oral health care services by family caregivers and care recipients: the LENTO intervention.","authors":"Shanza Razzaq, Irma Nykänen, Tarja Välimäki, Sohvi Koponen, Roosa-Maria Savela, Ursula Schwab, Anna Liisa Suominen","doi":"10.2340/aos.v83.40687","DOIUrl":"10.2340/aos.v83.40687","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to evaluate the impact of an individually tailored preventive oral health intervention on the use of oral health care services by older family caregivers (FCs) and their care recipients (CRs).</p><p><strong>Material and methods: </strong>A randomized controlled six and 12-month oral health intervention study included FCs and CRs aged ≥65 years living in Eastern Finland. The participants were randomly assigned to an intervention (FCs n = 53, CRs n = 47) and a control (FCs n = 39, CRs n = 35) group. Individually tailored oral health interventions for the FCs provided by a dental hygienist focused on oral hygiene and self-care. Generalized estimating equations were used to analyze the impact of intervention on the change in the use of oral health care services.</p><p><strong>Results: </strong>The intervention had no significant effect on the use of oral health care services by the FCs or their CRs. Traditional factors such as female gender, a higher number of teeth, toothache, no dental fear, and higher morbidity were significantly (p < 0.05) associated with an increased use of oral health care services in the FCs, but not among the CRs.</p><p><strong>Conclusions: </strong>Individually tailored preventive oral health intervention showed no effect on the use of oral health care services. To promote oral health among the elderly, specific interventions focusing on use of oral health care services are needed.</p><p><strong>Trial registration: </strong>clinicaltrials.gov/study/NCT04003493.</p>","PeriodicalId":7313,"journal":{"name":"Acta Odontologica Scandinavica","volume":"83 ","pages":"317-326"},"PeriodicalIF":1.4,"publicationDate":"2024-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11302500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141074760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Acta Odontologica Scandinavica
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