Global health journal (Amsterdam, Netherlands)最新文献_第3页

Co-morbidity of malaria and hypertension among adults in Nigeria: patterns, mechanisms, and health barriers 尼日利亚成年人中疟疾和高血压的合并症：模式、机制和健康障碍

Global health journal (Amsterdam, Netherlands)

Pub Date : 2025-09-01 DOI: 10.1016/j.glohj.2025.10.005

Ufuomanefe Cleopatra Omoemu , Modupe Oluwatemitope Oyedele , Boluwatife Samuel Awe , Kamara Alfred Osman , Fidelis Ogenetega Ejeheri

Objective

This review examined the co-morbidity of malaria and hypertension in Nigerian adults, with a focus on epidemiological trends, genetic and environmental risk factors, pathophysiological mechanisms, and systemic healthcare barriers.

Methods

A qualitative synthesis of peer-reviewed literature, national health surveys, and institutional reports published between 2000 and 2025 was conducted using thematic analysis. While centered on Nigeria, the review incorporated comparative insights from global studies on renin angiotensin aldosterone system polymorphisms, co-infection dynamics, and health service inequalities.

Results

The findings indicate overlapping risk factors including renin angiotensin aldosterone system gene polymorphisms, urbanization, and poverty. Angiotensin II demonstrates dual functions, contributing both to malaria suppression and to hypertension pathogenesis. Clinical challenges include diagnostic overlap, adverse drug interactions, and disparities in service delivery between rural and urban populations. These challenges particularly affect older adults and highlight systemic gaps in access, workforce distribution, and policy alignment.

Conclusion

The dual burden of malaria and hypertension in Nigeria requires integrated disease management strategies that address both communicable and non-communicable disease risks. Urgent priorities include multi-sectoral policy reforms, expanded rural health investments, and the adoption of precision medicine approaches guided by genetic profiling. The implications extend to clinical practice through co-screening and tailored treatment protocols and to public health policy, where integrated frameworks are essential to reducing inequities and improving long-term outcomes.

目的研究尼日利亚成年人疟疾和高血压的合并症，重点关注流行病学趋势、遗传和环境危险因素、病理生理机制和系统性卫生保健障碍。方法采用专题分析方法，对2000年至2025年间发表的同行评议文献、国家卫生调查和机构报告进行定性综合。虽然以尼日利亚为中心，但该综述纳入了肾素血管紧张素醛固酮系统多态性、合并感染动态和卫生服务不平等等全球研究的比较见解。结果肾素血管紧张素醛固酮系统基因多态性、城市化和贫困等因素重叠。血管紧张素II具有双重功能，既有助于抑制疟疾，又有助于高血压发病。临床挑战包括诊断重叠、药物不良相互作用以及城乡人口之间服务提供的差异。这些挑战尤其影响老年人，并突出了在获取、劳动力分布和政策协调方面的系统性差距。结论尼日利亚的疟疾和高血压双重负担需要采取综合疾病管理战略，同时应对传染病和非传染性疾病风险。紧迫的优先事项包括多部门政策改革、扩大农村卫生投资以及采用以基因图谱为指导的精准医疗方法。其影响通过联合筛查和量身定制的治疗方案扩展到临床实践，并扩展到公共卫生政策，在公共卫生政策中，综合框架对于减少不平等和改善长期成果至关重要。

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引用次数: 0

Access to health services and factors affecting musculoskeletal disorders among outdoor pollution workers following Sustainable Development Goals: a weakness in Thailand 可持续发展目标后室外污染工人获得卫生服务的机会和影响肌肉骨骼疾病的因素：泰国的弱点

Global health journal (Amsterdam, Netherlands)

Pub Date : 2025-06-01 DOI: 10.1016/j.glohj.2025.06.002

Anamai Thetkathuek , Marissa Kongsombatsuk , Teeranun Nakyai , Chan Pattama Polyong

Background

People working outdoors in the Map Ta Phut pollution control area of Thailand require comprehensive health monitoring. In the past, studies have been done on the health effects of pollutants. However, there are few studies on musculoskeletal disorders (MSDs), and Thailand is struggling to meet the Sustainable Development Goals.

Methods

This cross-sectional study examines access to health services and factors affecting MSDs among outdoor pollution workers (OPWs). The sample group includes OPWs, including local fisherman, street vendors, public car drivers, and traffic police. We studied 50 people from each of these groups, for a total of 200 people. Data were analyzed with inferential statistics using Chi-square test, McNemar test, and Univariate logistic regression.

Results

The OPWs reported experiencing significantly more total MSDs pain than they did in the past (P < 0.05). Factors affecting current MSDs pain, including occupation and working days per week, were significant (P < 0.05). The street vendor group and public car driver group had (odds ratio [OR] = 2.253, 95 % confidence interval [CI]: 1.101 to 5.019) and (OR = 2.681, 95 % CI: 1.191 to 6.032) times higher risks of MSDs pain, respectively. OPWs who work > 5 days per week had a (OR = 1.464, 95 % CI: 1.093 to 2.704) times higher risk of MSDs pain. 52.7 % of OPWs with MSDs, pain (n = 110) had received an annual health check-up. In the past year, 50.9 % had minor illnesses and 21.8 % had severe illnesses. OPWs receiving free treatment and visiting health service stations for no cost comprised 77.3 % and 51.8 %, respectively. 60.9 % used their right to receive treatment with universal health insurance cards.

Conclusions

The study indicates that occupational groups with MSDs pain problems should exercise this right, according to the worker protection law. Local health agencies should organize activities or create accessible media to promote preventive medicine services, as many OPWs believe that health services can only be accessed when illness occurs.

背景：在泰国Map Ta Phut污染控制区从事户外工作的人员需要进行全面的健康监测。在过去，已经对污染物对健康的影响进行了研究。然而，关于肌肉骨骼疾病（MSDs）的研究很少，泰国正在努力实现可持续发展目标。方法本横断面研究调查了室外污染工人（opw）获得卫生服务和影响MSDs的因素。样本群体包括opw，包括当地渔民、街头小贩、公共汽车司机和交通警察。我们研究了每组50人，总共200人。资料采用卡方检验、McNemar检验和单因素logistic回归进行推理统计分析。结果opw报告的msd总疼痛比过去明显增加(P <；0.05)。影响当前MSDs疼痛的因素，包括职业和每周工作天数，具有显著性(P <；0.05)。街头小贩组和公共汽车司机组分别（比值比[OR] = 2.253, 95%可信区间[CI]: 1.101 ~ 5.019）和（比值比[OR] = 2.681, 95%可信区间[CI]: 1.191 ~ 6.032）是MSDs疼痛风险的两倍。工作>；每周5天的MSDs疼痛风险（OR = 1.464, 95% CI: 1.093 ~ 2.704）高出1倍。有MSDs、疼痛的opw （n = 110）中有52.7%接受过年度健康检查。在过去一年中，50.9%的人患有轻微疾病，21.8%的人患有严重疾病。接受免费治疗和免费前往保健服务站的opw分别占77.3%和51.8%。60.9%的人利用全民健康保险卡接受治疗的权利。结论有MSDs疼痛问题的职业群体应根据《工人保护法》行使这一权利。地方卫生机构应组织活动或创建无障碍媒体，以促进预防医学服务，因为许多门诊医生认为，只有在生病时才能获得卫生服务。

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引用次数: 0

Occupational influences on dietary quality among postpartum women: a cross-sectional study in Beijing, China 职业对产后妇女饮食质量的影响：北京地区的一项横断面研究

Global health journal (Amsterdam, Netherlands)

Pub Date : 2025-06-01 DOI: 10.1016/j.glohj.2025.06.003

Jian Zhao, Min Zhang

Objective

Postpartum nutrition plays a critical role in maternal recovery and long-term health. However, the nutritional status of working mothers in the postpartum period remains understudied. This study aimed to assess the dietary quality of postpartum women in urban Beijing, identify occupational-related factors influencing their diet, and explore potential interventions to improve maternal nutrition during the postpartum period.

Methods

In this cross-sectional analysis, 554 women one year after delivery were recruited from ten community health centers. Sociodemographic, occupational and postpartum care variables were collected via questionnaire. Dietary intake over the preceding year was assessed using a food frequency questionnaire. The modified dietary balance index for postpartum women were used for dietary quality assessment.

Results

The study revealed severe dietary imbalances among postpartum women, characterized by excessive consumption of cereals, eggs, and meats, while their intake of vegetables, fruits, and dairy products was inadequate. According to dietary balance index for postpartum women, 66.25 % of mothers showed varying degrees of excessive intake. 45.31 % of mothers experienced varying levels of insufficient intake, with only 19.86 % of participants having a relatively balanced diet. Occupational differences were observed, with women in the commercial employment group showing higher levels of excessive food intake. The analysis of influencing factors showed that family monthly income, maternity leave, and postpartum care significantly affected the dietary quality.

Conclusions

Postpartum women in Beijing experience widespread dietary imbalances, with both excesses and deficiencies. Occupational context and related factors significantly shape diet quality. These findings highlight the need for targeted nutritional interventions tailored to the specific challenges of different occupational groups.

目的产后营养对产妇的康复和长期健康起着至关重要的作用。然而，职业母亲在产后期间的营养状况仍未得到充分研究。本研究旨在评估北京城市产后妇女的饮食质量，识别影响其饮食的职业相关因素，并探讨改善产后产妇营养的潜在干预措施。方法在横断面分析中，从10个社区卫生中心招募了554名分娩后一年的妇女。通过问卷调查收集社会人口学、职业和产后护理变量。使用食物频率问卷对前一年的饮食摄入量进行评估。采用改良后的产后妇女膳食平衡指数进行膳食质量评价。结果研究揭示了产后妇女严重的饮食失衡，其特点是过量食用谷物、鸡蛋和肉类，而蔬菜、水果和乳制品的摄入量不足。根据产后妇女膳食平衡指数，66.25%的母亲表现出不同程度的过量摄入。45.31%的母亲有不同程度的摄入不足，只有19.86%的参与者有相对均衡的饮食。观察到职业差异，商业就业组的妇女表现出更高水平的过度食物摄入。影响因素分析显示，家庭月收入、产假、产后护理对饮食质量有显著影响。结论北京地区产后妇女普遍存在膳食失衡，既有过量，也有不足。职业环境及相关因素对饮食质量有显著影响。这些发现突出表明，需要针对不同职业群体的具体挑战采取有针对性的营养干预措施。

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引用次数: 0

Mortality trends and discrepancies among geographic and demographic factors in the USA: pre-, during and post-pandemic analysis 美国地理和人口因素之间的死亡率趋势和差异：大流行之前、期间和之后的分析

Global health journal (Amsterdam, Netherlands)

Pub Date : 2025-06-01 DOI: 10.1016/j.glohj.2024.12.001

Siddharth Raj Gupta

Objective

Human mortality is affected by a lot of different factors. Geographic and demographic variations are two such criteria that play significant importance in establishing the variation in mortality rate.

Methods

The current work uses data collected from the Centers for Disease Control and Prevention from 2018 to 2021 to study the dependence of mortality on several parameters such as gender, race, and age group. The analysis looks at all the different causes of death registered in the database and shows how they vary with not only the demographic variables mentioned above but also geographic variables such as states in the USA. The variation in trends pre-, during, and post-pandemic is also investigated. The study undertakes several multi-factorial relations such as location-age group, location-gender, age group-gender, and a blanket study across all the races for 2018‒2021.

Results

Texas, California, and Florida were analyzed to be the states with the most number of deaths for the majority of causes. The study shows that before the pandemic two of the most critical causes of death identified were Atherosclerotic heart disease and Alzheimer's disease which was outnumbered by coronavirus disease 2019 in years 2020 and 2021 for the age groups of 35‒84 years.

Conclusion

The outcome of the study clearly shows the irrational availability of data among different ages, states, and races. In addition, it helps to provide interesting insights into how the mortality trends relate to demographic and geographic factors and point out the discrepancies among them.

人类的死亡率受到许多不同因素的影响。地理和人口变化是确定死亡率变化的两个重要标准。方法本研究使用美国疾病控制与预防中心2018 - 2021年的数据，研究死亡率与性别、种族、年龄组等参数的相关性。该分析着眼于数据库中登记的所有不同死因，并显示它们如何随着上述人口变量以及美国各州等地理变量而变化。还调查了大流行之前、期间和之后的趋势变化。该研究涵盖了多个多因素关系，如地点-年龄组、地点-性别、年龄组-性别，并对2018-2021年的所有种族进行了全面研究。结果得克萨斯州、加利福尼亚州和佛罗里达州被分析为大多数原因导致死亡人数最多的州。该研究表明，在大流行之前，确定的两种最重要的死亡原因是动脉粥样硬化性心脏病和阿尔茨海默病，在2020年和2021年，35-84岁年龄组的冠状病毒病人数超过了冠状病毒病2019。结论研究结果清楚地表明，不同年龄、州和种族的数据可得性不合理。此外，它有助于提供关于死亡率趋势与人口和地理因素之间关系的有趣见解，并指出它们之间的差异。

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引用次数: 0

Digital health interventions for pregnant women and mothers with under 5-year-olds in low- and middle-income countries: a scoping review 低收入和中等收入国家孕妇和5岁以下儿童母亲的数字卫生干预措施：范围审查

Global health journal (Amsterdam, Netherlands)

Pub Date : 2025-06-01 DOI: 10.1016/j.glohj.2025.06.008

Frank Adusei-Mensah , Livhuwani Muthelo , Mxolisi Welcome Ngwenya , MH Mphasha , Jussi Kauhanen

Objective

This scoping review explores digital health interventions used to improve maternal health and the health of children under-5-year-olds in rural areas of low- and middle-income countries (LMICs), identifying current practices and research gaps.

Methods

Guided by PRISMA Extension for Scoping Reviews, a comprehensive search was conducted across PubMed, Web of Science, and grey literature search with Google Scholar, and the South African National Electronic Theses and Dissertations Portal. MeSH terms and Boolean operators were used. Studies were screened using the Population, Concept, and Context framework, and data were extracted systematically.

Results

Of 5,114 records, 63 met inclusion criteria. Digital health interventions, particularly mobile health, were found to enhance service delivery, education, and support for maternal and child health in LMICs. However, challenges such as limited access to technology, digital literacy, and cultural barriers persist. Contextual factors, including geography and sociocultural norms, significantly influenced implementation success.

Conclusion

Digital health interventions show promise in improving maternal and child health in LMICs. However, regional disparities, technological limitations, and cultural misalignment hinder scalability. Future research should focus on culturally adaptive, community-engaged approaches and long-term impact assessments to support sustainable health promotion in low-resource settings.

本范围审查探讨了用于改善低收入和中等收入国家农村地区孕产妇健康和5岁以下儿童健康的数字卫生干预措施，确定了当前的做法和研究差距。方法在PRISMA扩展范围评价的指导下，通过PubMed、Web of Science、谷歌Scholar和南非国家电子论文门户网站进行灰色文献检索。使用了MeSH术语和布尔运算符。使用人口、概念和背景框架筛选研究，并系统地提取数据。结果5114例患者中，63例符合纳入标准。研究发现，数字保健干预措施，特别是移动保健措施，可加强中低收入国家的服务提供、教育和对妇幼保健的支持。然而，技术获取受限、数字素养和文化障碍等挑战依然存在。背景因素，包括地理和社会文化规范，显著影响了实施的成功。结论数字卫生干预措施在改善中低收入国家孕产妇和儿童健康方面表现出良好的前景。然而，地区差异、技术限制和文化错位阻碍了可扩展性。未来的研究应侧重于文化适应性、社区参与的方法和长期影响评估，以支持低资源环境中可持续的健康促进。

{"title":"Digital health interventions for pregnant women and mothers with under 5-year-olds in low- and middle-income countries: a scoping review","authors":"Frank Adusei-Mensah , Livhuwani Muthelo , Mxolisi Welcome Ngwenya , MH Mphasha , Jussi Kauhanen","doi":"10.1016/j.glohj.2025.06.008","DOIUrl":"10.1016/j.glohj.2025.06.008","url":null,"abstract":"<div><h3>Objective</h3><div>This scoping review explores digital health interventions used to improve maternal health and the health of children under-5-year-olds in rural areas of low- and middle-income countries (LMICs), identifying current practices and research gaps.</div></div><div><h3>Methods</h3><div>Guided by PRISMA Extension for Scoping Reviews, a comprehensive search was conducted across PubMed, Web of Science, and grey literature search with Google Scholar, and the South African National Electronic Theses and Dissertations Portal. MeSH terms and Boolean operators were used. Studies were screened using the Population, Concept, and Context framework, and data were extracted systematically.</div></div><div><h3>Results</h3><div>Of 5,114 records, 63 met inclusion criteria. Digital health interventions, particularly mobile health, were found to enhance service delivery, education, and support for maternal and child health in LMICs. However, challenges such as limited access to technology, digital literacy, and cultural barriers persist. Contextual factors, including geography and sociocultural norms, significantly influenced implementation success.</div></div><div><h3>Conclusion</h3><div>Digital health interventions show promise in improving maternal and child health in LMICs. However, regional disparities, technological limitations, and cultural misalignment hinder scalability. Future research should focus on culturally adaptive, community-engaged approaches and long-term impact assessments to support sustainable health promotion in low-resource settings.</div></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"9 2","pages":"Pages 113-123"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144703661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Work engagement levels and correlates among physician assistants in Ghana: a cross-sectional study 加纳医师助理的工作投入水平及其相关性：一项横断面研究

Global health journal (Amsterdam, Netherlands)

Pub Date : 2025-06-01 DOI: 10.1016/j.glohj.2025.06.011

Patrick Kwame Akwaboah , Kofi Adjei Ntiri , George Baah , Richmond Larweh , Akosua Animwah Somuah

Background

Work engagement (WE) is critical to quality primary healthcare delivery. However, limited research has explored its levels and determinants among healthcare professionals in low- and middle-income countries. This study assessed the levels and correlates of work engagement among physician assistants (PAs) in Ghana.

Methods

A cross-sectional study was conducted among 439 PAs from October to December 2024. Participants were recruited via emails, social media platforms, and posters featuring study links and scannable questionnaire codes. WE was measured using the validated Utrecht Work Engagement Scale questionnaire.

Results

Overall, WE levels were average, with similar trends across the three subdomains. In the bootstrapped multivariate linear regression model, anxiety was negatively associated with WE (β = − 0.49, 95 % confidence interval [CI]: −0.77 to −0.21). Conversely, working in an urban area (β = 0.36, 95 % CI: 0.05 to 0.67), holding the rank of PA/Senior PA (β = 0.27, 95 % CI: 0.03 to 0.52), reporting good self-rated health (β = 0.54, 95 % CI: 0.19 to 0.88), and working at health centers (β = 0.86, 95 % CI: 0.22 to 1.50) were positively associated with WE levels.

Conclusion

WE levels are average in the study sample, highlighting the need for strategic interventions to improve and sustain the healthcare workforce’s motivation and performance. Addressing workplace stressors, enhancing professional development opportunities, and fostering supportive work environments could improve engagement among PAs and healthcare professionals in general. Strengthening WE is essential for ensuring resilient quality primary healthcare systems and achieving the goals of universal health coverage.

backfoundations的参与对于提供高质量的初级卫生保健至关重要。然而，有限的研究探讨了低收入和中等收入国家卫生保健专业人员的水平和决定因素。本研究评估了加纳医师助理（PAs）的工作投入水平和相关关系。方法于2024年10月至12月对439名PAs进行横断面研究。参与者是通过电子邮件、社交媒体平台和带有研究链接和可扫描问卷代码的海报招募的。我们使用经过验证的乌得勒支工作投入量表问卷进行测量。结果总体而言，WE水平为平均水平，三个子域的趋势相似。在自举多元线性回归模型中，焦虑与WE呈负相关（β = - 0.49, 95%置信区间[CI]: - 0.77至- 0.21）。相反，在城市地区工作（β = 0.36, 95% CI: 0.05至0.67），持有PA/Senior PA等级（β = 0.27, 95% CI: 0.03至0.52），报告良好的自评健康（β = 0.54, 95% CI: 0.19至0.88），以及在健康中心工作（β = 0.86, 95% CI: 0.22至1.50）与WE水平呈正相关。结论：在研究样本中，we水平处于平均水平，强调需要采取战略干预措施来改善和维持医疗保健人员的动机和绩效。解决工作场所的压力源，增加专业发展机会，培养支持性的工作环境可以总体上提高执业医师和医疗保健专业人员的参与度。加强WE对于确保有复原力的高质量初级卫生保健系统和实现全民健康覆盖的目标至关重要。

{"title":"Work engagement levels and correlates among physician assistants in Ghana: a cross-sectional study","authors":"Patrick Kwame Akwaboah , Kofi Adjei Ntiri , George Baah , Richmond Larweh , Akosua Animwah Somuah","doi":"10.1016/j.glohj.2025.06.011","DOIUrl":"10.1016/j.glohj.2025.06.011","url":null,"abstract":"<div><h3>Background</h3><div>Work engagement (WE) is critical to quality primary healthcare delivery. However, limited research has explored its levels and determinants among healthcare professionals in low- and middle-income countries. This study assessed the levels and correlates of work engagement among physician assistants (PAs) in Ghana.</div></div><div><h3>Methods</h3><div>A cross-sectional study was conducted among 439 PAs from October to December 2024. Participants were recruited via emails, social media platforms, and posters featuring study links and scannable questionnaire codes. WE was measured using the validated Utrecht Work Engagement Scale questionnaire.</div></div><div><h3>Results</h3><div>Overall, WE levels were average, with similar trends across the three subdomains. In the bootstrapped multivariate linear regression model, anxiety was negatively associated with WE (<em>β</em> = − 0.49, 95 % confidence interval [<em>CI</em>]: −0.77 to −0.21). Conversely, working in an urban area (<em>β</em> = 0.36, 95 % <em>CI</em>: 0.05 to 0.67), holding the rank of PA/Senior PA (<em>β</em> = 0.27, 95 % <em>CI</em>: 0.03 to 0.52), reporting good self-rated health <em>(β</em> = 0.54, 95 % <em>CI</em>: 0.19 to 0.88), and working at health centers (<em>β</em> = 0.86, 95 % <em>CI</em>: 0.22 to 1.50) were positively associated with WE levels.</div></div><div><h3>Conclusion</h3><div>WE levels are average in the study sample, highlighting the need for strategic interventions to improve and sustain the healthcare workforce’s motivation and performance. Addressing workplace stressors, enhancing professional development opportunities, and fostering supportive work environments could improve engagement among PAs and healthcare professionals in general. Strengthening WE is essential for ensuring resilient quality primary healthcare systems and achieving the goals of universal health coverage.</div></div>","PeriodicalId":73164,"journal":{"name":"Global health journal (Amsterdam, Netherlands)","volume":"9 2","pages":"Pages 153-158"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144703757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Implementation of school-based mass drug administration of praziquantel in Nigeria: barriers, facilitators and opportunities for improvement 在尼日利亚实施以学校为基础的吡喹酮大规模药物管理：障碍、促进因素和改进机会

Global health journal (Amsterdam, Netherlands)

Pub Date : 2025-06-01 DOI: 10.1016/j.glohj.2025.06.007

Obidimma Ezezika , Omolola Olorunbiyi , Jenny Gong , Olabanji Surakat , Jonathan Ogoji , Obiageli Nebe

Objective

The World Health Organization recommends annual preventive chemotherapy with a single dose of praziquantel at ≥ 75 % treatment coverage, but as of 2021, the national coverage rate in Nigeria among children falls below 10 %. This qualitative study sought to explore the barriers and facilitators to implementing large-scale praziquantel mass drug administration (MDA) programs for school-aged children in Nigeria to delineate tools and strategies that could improve the scaling-up and effectiveness of school-based praziquantel MDA programs.

Methods

An exploratory qualitative study was conducted with stakeholders with experience in MDAs involving praziquantel or related preventive chemotherapy drugs in Nigeria. Through snowball sampling, 30 stakeholders with experience in praziquantel school-based MDA in Nigeria were interviewed. An inductive approach was used to generate broad themes based on the barriers and facilitators identified by the key informants.

Results

A total of 45 barriers and 36 facilitators were identified and grouped inductively into eight themes: funding and resources, design and composition of praziquantel tablets, knowledge and awareness mobilization, government, nongovernmental organization, and school engagement, data management, logistics, training, and security.

Conclusion

This qualitative study reveals a wide range of barriers and facilitators in the MDA of praziquantel in Nigeria and uncovered critical points along the implementation pathway based on the locus of the barriers and facilitators identified. Collaboration with national, international, and non-profit organizations, and drug education through promotional materials, were the most frequently mentioned facilitators of the MDA program. In addition, insufficient program funding, and the complexity of the supply chain were the most cited barriers.

世界卫生组织建议每年使用单剂量吡喹酮进行预防性化疗，治疗覆盖率≥75%，但截至2021年，尼日利亚儿童的全国覆盖率低于10%。本定性研究旨在探索尼日利亚学龄儿童实施大规模吡喹酮大规模药物管理（MDA）计划的障碍和促进因素，以描绘可以提高以学校为基础的吡喹酮大规模药物管理（MDA）计划的规模和有效性的工具和策略。方法在尼日利亚与具有吡喹酮或相关预防性化疗药物MDAs经验的利益相关者进行探索性定性研究。通过滚雪球抽样，对尼日利亚30名具有吡喹酮学校MDA经验的利益攸关方进行了访谈。采用归纳方法，根据主要举报人确定的障碍和促进因素产生广泛的主题。结果共确定了45个障碍和36个促进因素，并归纳为8个主题：资金和资源、吡喹酮片的设计和组成、知识和意识动员、政府、非政府组织和学校参与、数据管理、后勤、培训和安全。结论本定性研究揭示了吡喹酮在尼日利亚的MDA中存在广泛的障碍和促进因素，并根据所发现的障碍和促进因素的位点揭示了实施路径上的关键点。与国家、国际和非营利组织的合作，以及通过宣传材料进行药物教育，是MDA项目最常提到的促进因素。此外，项目资金不足和供应链的复杂性是最常被提及的障碍。

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引用次数: 0

Safe and healthy working environment for occupational health: advancing evidence-informed policy-making 安全和健康的工作环境促进职业健康：推进循证决策

Global health journal (Amsterdam, Netherlands)

Pub Date : 2025-06-01 DOI: 10.1016/j.glohj.2025.06.005

Min Zhang

引用次数: 0

The intersection of mpox outbreak and mental health: a bibliometric analysis of current research trends 麻疹爆发与心理健康的交叉：当前研究趋势的文献计量学分析

Global health journal (Amsterdam, Netherlands)

Pub Date : 2025-06-01 DOI: 10.1016/j.glohj.2025.06.009

Ovinuchi Ejiohuo , Cyril Onwuelazu Uteh , Olubusola O. Olaleye , Samuel Adefisoye Lawal , Abdulkadir Yusif Maigoro , Helen Onyenka

Background and objectives

The ongoing mpox outbreaks have garnered significant attention due to their public health implications, particularly the potential mental health impacts. Despite the growing concern, there has been limited exploration of the intersection between mpox and mental health within the research literature. This study aims to conduct a comprehensive bibliometric analysis to examine global research trends, regional distribution, and thematic focus areas related to mpox's psychological and psychiatric implications.

Methods

We conducted a bibliometric analysis using Scopus and the Web of Science database. The analysis was carried out using the R-bibliometrics package and involved identifying literature on mpox and mental health, focusing on global research trends, regional distribution, and thematic areas of study. The analysis included 416 documents obtained from 295 sources from January 1, 2014 to August 27, 2024.

Results

Our analysis revealed a growing but unevenly distributed literature on mpox and mental health. Most studies concentrated on the relationship between mpox and conditions such as depression and anxiety, while other psychiatric outcomes remain underexplored. The geographic distribution of research was also uneven, with regions like Europe and the Americas receiving more focus than others.

Conclusions

The study highlights the need for more targeted research on the mental health sequelae of mpox, particularly for vulnerable populations and regions that are currently underrepresented in the literature. Future research should include longitudinal studies to assess the long-term effects of mpox on mental health and the development of robust methodologies to establish causality. Integrating mental health considerations into public health responses to mpox outbreaks is crucial, with significant implications for research, policy, and clinical practice.

背景和目的由于其公共卫生影响，特别是潜在的心理健康影响，正在发生的麻疹疫情引起了极大的关注。尽管越来越受到关注，但在研究文献中，对mpox和心理健康之间的交集的探索有限。本研究旨在进行全面的文献计量分析，以检查与mpox心理和精神影响相关的全球研究趋势、区域分布和专题重点领域。方法采用Scopus和Web of Science数据库进行文献计量学分析。使用r -文献计量学软件包进行分析，包括确定关于麻疹和心理健康的文献，重点关注全球研究趋势、区域分布和专题研究领域。该分析包括从2014年1月1日至2024年8月27日从295个来源获得的416份文件。结果我们的分析显示，关于麻疹和心理健康的文献越来越多，但分布不均匀。大多数研究集中在m痘与抑郁和焦虑等疾病之间的关系上，而其他精神疾病的结果仍未得到充分探讨。研究的地理分布也不均衡，欧洲和美洲等地区比其他地区受到更多关注。结论：该研究强调需要对m痘的心理健康后遗症进行更有针对性的研究，特别是针对目前文献中代表性不足的弱势人群和地区。未来的研究应包括纵向研究，以评估mpox对精神健康的长期影响，并开发可靠的方法来确定因果关系。将精神卫生考虑纳入对麻疹暴发的公共卫生反应至关重要，对研究、政策和临床实践具有重大意义。

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引用次数: 0

Impact of indoor air quality and workplace conditions on sick building syndrome among healthcare workers: a case study in Nakhon Si Thammarat, Thailand 室内空气质量和工作场所条件对卫生保健工作者患病建筑综合征的影响：泰国那空西塔玛拉的案例研究

Global health journal (Amsterdam, Netherlands)

Pub Date : 2025-06-01 DOI: 10.1016/j.glohj.2025.06.004

Kittithat Sudchoo , Sarisa Kaewkheiw , Punyatip Sukju , Thapanee Thongsri , Achiraya Choengdee , Nazri Che Dom , Nopadol Precha

Objective

Sick building syndrome (SBS) is a significant health concern among healthcare workers, exacerbated by prolonged exposure to indoor air pollutants and inadequate environmental conditions. Our study aims to explore the prevalence of SBS and its association with indoor air quality and workplace environments among healthcare workers in five hospital departments in Nakhon Si Thammarat, Thailand.

Methods

Indoor air quality was assessed over eight days, measuring microbial concentrations (bacteria, fungi), temperature, humidity, and carbon dioxide levels. Demographic data and SBS symptoms were also collected from healthcare workers.

Results

The findings revealed that fungal concentrations were highest in the pharmacy (51.95 ± 37.59) colony forming units (CFU) per m³, while bacterial concentrations peaked in the outpatient department (265.06 ± 49.46) CFU/m³. The study identified Staphylococcus hominis and Micrococcus luteus as the dominant microbial species in the air environment. A moderate positive correlation was found between bacterial concentrations and humidity (r = 0.43, P = 0.046). SBS symptoms were prevalent among healthcare workers, with 75.58 % reporting issues like dry eyes and fatigue. The total complaint score for SBS correlated positively with indoor pollutant levels, especially fungi (r = 0.38, P < 0.001). Frequent cleaning reduced SBS complaints significantly (P < 0.001).

Conclusion

Hospital departments with more frequent cleaning practices exhibited lower SBS complaints, highlighting the importance of cleaning frequency in reducing SBS-related issues. These findings provide actionable insights for improving workplace safety and indoor air quality in healthcare settings.

目的病态建筑综合征（SBS）是卫生保健工作者的重要健康问题，因长期暴露于室内空气污染物和不适当的环境条件而加剧。本研究旨在探讨泰国那空市5个医院部门的医护人员中SBS的患病率及其与室内空气质量和工作环境的关系。方法通过测量室内微生物浓度（细菌、真菌）、温度、湿度和二氧化碳水平，对室内空气质量进行为期8天的评估。还收集了卫生保健工作者的人口统计数据和SBS症状。结果真菌浓度以药房最高（51.95±37.59）CFU/m³，门诊最高（265.06±49.46）CFU/m³；本研究确定了人类葡萄球菌和黄体微球菌是空气环境中的优势微生物种。细菌浓度与湿度呈中等正相关（r = 0.43, P = 0.046）。SBS症状在卫生保健工作者中很普遍，75.58%的人报告眼睛干涩和疲劳等问题。SBS投诉总得分与室内污染物水平呈正相关，尤其是真菌(r = 0.38, P <；0.001)。经常清洁可显著减少SBS投诉(P <；0.001)。结论清洁频率越高的科室SBS投诉越少，说明清洁频率对减少SBS相关问题的重要性。这些发现为改善医疗机构的工作场所安全和室内空气质量提供了可行的见解。

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