Tai-You Guo, C-C Kuo, Ming-Hua Chen, Ching-I Lin, Jenq-Shyong Chan, P. Hsiao, H. Shyu
Diabetes mellitus is the major cause of retinopathy, nephropathy and neuropathy. Hyperglycemia is one of major major advised effect on diabetes mellitus. Hemichorea-hemiballism, a rare manifestation of nonketotic hyperglycemia, characterized by involuntary arrhythmic motions in one side of the body which results from focal lesions in the contralateral basal ganglia. Here, we present a 39-year-old woman with violent involuntary rapid and irregular movements of left limbs three days prior to emergency department. Nonketotic hyperglycemia related hemichorea-hemiballism had been confirmed by biochemistry examination and brain computed tomography (CT). Aggressive glucose control with insulin was administered. Her symptoms got improvement gradually after euglycemia two weeks later.
{"title":"Comparison of Hemichorea-Hemiballism between Acute Stroke and Nonketotic-Hyperglycinemia in the Clinical Scenario: Report of a Rare Diabetic Complication","authors":"Tai-You Guo, C-C Kuo, Ming-Hua Chen, Ching-I Lin, Jenq-Shyong Chan, P. Hsiao, H. Shyu","doi":"10.3823/2600","DOIUrl":"https://doi.org/10.3823/2600","url":null,"abstract":"Diabetes mellitus is the major cause of retinopathy, nephropathy and neuropathy. Hyperglycemia is one of major major advised effect on diabetes mellitus. Hemichorea-hemiballism, a rare manifestation of nonketotic hyperglycemia, characterized by involuntary arrhythmic motions in one side of the body which results from focal lesions in the contralateral basal ganglia. Here, we present a 39-year-old woman with violent involuntary rapid and irregular movements of left limbs three days prior to emergency department. Nonketotic hyperglycemia related hemichorea-hemiballism had been confirmed by biochemistry examination and brain computed tomography (CT). Aggressive glucose control with insulin was administered. Her symptoms got improvement gradually after euglycemia two weeks later.","PeriodicalId":73409,"journal":{"name":"International archives of medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42229996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. L. Neto, J. L. M. Freitas, Mayana Rodrigues de Melo Alves
Objective: Evaluating evidence involving the assurance of health rights for refugee population throughout the world by systematic revision with metanalysis. Data Source: the following database was used: MEDLINE, accessed via Virtual Health Library (BVS), and SCOPUS. In order to make more assured and straightforward research, the authors chose to unify all the descriptors (MeSH) using the operator AND on the following form: (Refugees AND Right to health AND Human Rights). Study Selection: The primary selection occur through triage of titles and abstracts followed by eligibility criteria based on full reading of the articles selected under previously stablished inclusion criteria. Data Extraction: Some of the information were extracted from studies enclosing author, year, type of participants and its respective numbers, type of intervention, number of sessions or time of follow-up, and outcomes. Results: The research strategies resulted in 201 articles. Considering inclusion and exclusion criteria, 10 studies were included in the sample (N). The metanalysis make possible to assess the failure of the effective policy towards the refugee population´s welfare, thus there is an effective close proximity with the absence line, I^2 (variation in ES attributable to heterogeneity) = 98.32%; Estimate of between-study variance Tau^2 = 0.04; Test of ES=0: z = 1.08 p = 0.00. Conclusion: The lack of access to information, the language and cultural issues, and the oddness/estrangement over the hosting country are major factors contributing for the refugee´s health precariousness in making it difficult in its access. The report “Global Trends” of the United Nations High Commissioner for Refugees (UNHCR) indicate that such difficulties in the health access may be related to the level of social-economic development of the hosting countries. There are plenty of difficulties on the accessing health services, among then the lack of official documentation and information. Objective: Evaluating evidence involving the assurance of health rights for refugee population throughout the world by systematic revision with metanalysis. Data Source: the following database was used: MEDLINE, accessed via Virtual Health Library (BVS), and SCOPUS. In order to make more assured and straightforward research, the authors chose to unify all the descriptors (MeSH) using the operator AND on the following form: (Refugees AND Right to health AND Human Rights). Study Selection: The primary selection occur through triage of titles and abstracts followed by eligibility criteria based on full reading of the articles selected under previously stablished inclusion criteria. Data Extraction: Some of the information were extracted from studies enclosing author, year, type of participants and its respective numbers, type of intervention, number of sessions or time of follow-up, and outcomes. Results: The research strategies resulted in 201 articles. Considering inclusion and exclusion crit
目的:通过荟萃分析的系统修订来评估涉及全球难民人口健康权保障的证据。数据来源:使用以下数据库:MEDLINE，通过虚拟健康图书馆(Virtual Health Library, BVS)和SCOPUS访问。为了使研究更加可靠和直接，作者选择在以下表格上使用and运算符统一所有描述符(MeSH):(难民和健康权和人权)。研究选择:主要的选择是通过标题和摘要的分类，然后是根据先前建立的纳入标准全面阅读文章的资格标准。数据提取:部分信息从研究中提取，包括作者、年份、参与者类型及其各自的人数、干预类型、随访次数或时间以及结果。结果:研究策略共纳入201篇文章。考虑到纳入和排除标准，样本中纳入了10项研究(N)。荟萃分析使评估有效政策对难民人口福利的失败成为可能，因此与缺失线的有效接近度为I^2(归因于异质性的ES变异)= 98.32%;研究间方差估计Tau^2 = 0.04;检验ES=0: z = 1.08 p = 0.00。结论:无法获得信息、语言和文化问题以及对东道国的奇怪/疏远是导致难民健康不稳定的主要因素，使其难以获得信息。联合国难民事务高级专员办事处(难民专员办事处)的报告《全球趋势》表明，获得保健服务方面的这种困难可能与东道国的社会经济发展水平有关。在获得保健服务方面有许多困难，其中包括缺乏官方文件和信息。目的:通过荟萃分析的系统修订来评估涉及全球难民人口健康权保障的证据。数据来源:使用以下数据库:MEDLINE，通过虚拟健康图书馆(Virtual Health Library, BVS)和SCOPUS访问。为了使研究更加可靠和直接，作者选择在以下表格上使用and运算符统一所有描述符(MeSH):(难民和健康权和人权)。研究选择:主要的选择是通过标题和摘要的分类，然后是根据先前建立的纳入标准全面阅读文章的资格标准。数据提取:部分信息从研究中提取，包括作者、年份、参与者类型及其各自的人数、干预类型、随访次数或时间以及结果。结果:研究策略共纳入201篇文章。考虑到纳入和排除标准，样本中纳入了10项研究(N)。荟萃分析使评估有效政策对难民人口福利的失败成为可能，因此与缺失线的有效接近度为I^2(归因于异质性的ES变异)= 98.32%;研究间方差估计Tau^2 = 0.04;检验ES=0: z = 1.08 p = 0.00。结论:无法获得信息、语言和文化问题以及对东道国的奇怪/疏远是导致难民健康不稳定的主要因素，使其难以获得信息。联合国难民事务高级专员办事处(难民专员办事处)的报告《全球趋势》表明，获得保健服务方面的这种困难可能与东道国的社会经济发展水平有关。在获得保健服务方面有许多困难，其中包括缺乏官方文件和信息。
{"title":"Barriers to effective right of access to health: a systematic review with metanalysis","authors":"M. L. Neto, J. L. M. Freitas, Mayana Rodrigues de Melo Alves","doi":"10.3823/2599","DOIUrl":"https://doi.org/10.3823/2599","url":null,"abstract":"Objective: Evaluating evidence involving the assurance of health rights for refugee population throughout the world by systematic revision with metanalysis. \u0000Data Source: the following database was used: MEDLINE, accessed via Virtual Health Library (BVS), and SCOPUS. In order to make more assured and straightforward research, the authors chose to unify all the descriptors (MeSH) using the operator AND on the following form: (Refugees AND Right to health AND Human Rights). \u0000Study Selection: The primary selection occur through triage of titles and abstracts followed by eligibility criteria based on full reading of the articles selected under previously stablished inclusion criteria. \u0000Data Extraction: Some of the information were extracted from studies enclosing author, year, type of participants and its respective numbers, type of intervention, number of sessions or time of follow-up, and outcomes. \u0000Results: The research strategies resulted in 201 articles. Considering inclusion and exclusion criteria, 10 studies were included in the sample (N). The metanalysis make possible to assess the failure of the effective policy towards the refugee population´s welfare, thus there is an effective close proximity with the absence line, I^2 (variation in ES attributable to heterogeneity) = 98.32%; Estimate of between-study variance Tau^2 = 0.04; Test of ES=0: z = 1.08 p = 0.00. \u0000Conclusion: The lack of access to information, the language and cultural issues, and the oddness/estrangement over the hosting country are major factors contributing for the refugee´s health precariousness in making it difficult in its access. The report “Global Trends” of the United Nations High Commissioner for Refugees (UNHCR) indicate that such difficulties in the health access may be related to the level of social-economic development of the hosting countries. There are plenty of difficulties on the accessing health services, among then the lack of official documentation and information. \u0000Objective: Evaluating evidence involving the assurance of health rights for refugee population throughout the world by systematic revision with metanalysis. \u0000Data Source: the following database was used: MEDLINE, accessed via Virtual Health Library (BVS), and SCOPUS. In order to make more assured and straightforward research, the authors chose to unify all the descriptors (MeSH) using the operator AND on the following form: (Refugees AND Right to health AND Human Rights). \u0000Study Selection: The primary selection occur through triage of titles and abstracts followed by eligibility criteria based on full reading of the articles selected under previously stablished inclusion criteria. \u0000Data Extraction: Some of the information were extracted from studies enclosing author, year, type of participants and its respective numbers, type of intervention, number of sessions or time of follow-up, and outcomes. \u0000Results: The research strategies resulted in 201 articles. Considering inclusion and exclusion crit","PeriodicalId":73409,"journal":{"name":"International archives of medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41776102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kathe Tavares Advincula, T. C. Cavalcante, Uana Shele Teles Cavalcante, Stefânia Carolina Ferreira Rodrigues, N. Vidal, Francisco Telésforo Celestino Junior, Aldrovando Nery de Aguiar Junior, Kécia Silva Damasceno, M. L. Neto
Introduction: It is estimated that 20% of pregnant women from developing countries, including Brazil, are subjected to anxiety situations, and that the prevalence of antenatal depression ranges from 7 to 15%. Objective: To identify the negative influence of psychosocial aspects during pregnancy. Results: In Western modern civilization, child bearing is often seen as a source of happiness to women. Thus, it is unlikely to relate sadness to the status of pregnancy, which is corroborated by the almost inexistent body of evidence documenting epidemiological data regarding antenatal depression and suicidal ideation during pregnancy. Conclusions: Results point towards a low prevalence of suicidal ideation among pregnant women, possibly due to the fact that practically no assessment of mental state is done during the antenatal period. A prevention strategy targeted at identifying harmful pregnant women’s behavior and psychosocial aspects is needed, so as to early diagnose depression, suicidal ideation and other risk factors among this population. Keywords: Suicide; Suicidal ideation; Depressive Symptoms; Pregnancy, high-risk
{"title":"The Suicide risk among women with high-risk pregnancies","authors":"Kathe Tavares Advincula, T. C. Cavalcante, Uana Shele Teles Cavalcante, Stefânia Carolina Ferreira Rodrigues, N. Vidal, Francisco Telésforo Celestino Junior, Aldrovando Nery de Aguiar Junior, Kécia Silva Damasceno, M. L. Neto","doi":"10.3823/2598","DOIUrl":"https://doi.org/10.3823/2598","url":null,"abstract":"Introduction: It is estimated that 20% of pregnant women from developing countries, including Brazil, are subjected to anxiety situations, and that the prevalence of antenatal depression ranges from 7 to 15%. \u0000Objective: To identify the negative influence of psychosocial aspects during pregnancy. \u0000Results: In Western modern civilization, child bearing is often seen as a source of happiness to women. Thus, it is unlikely to relate sadness to the status of pregnancy, which is corroborated by the almost inexistent body of evidence documenting epidemiological data regarding antenatal depression and suicidal ideation during pregnancy. \u0000Conclusions: Results point towards a low prevalence of suicidal ideation among pregnant women, possibly due to the fact that practically no assessment of mental state is done during the antenatal period. A prevention strategy targeted at identifying harmful pregnant women’s behavior and psychosocial aspects is needed, so as to early diagnose depression, suicidal ideation and other risk factors among this population. \u0000Keywords: Suicide; Suicidal ideation; Depressive Symptoms; Pregnancy, high-risk","PeriodicalId":73409,"journal":{"name":"International archives of medicine","volume":" 641","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41251904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Érico Gurgel Amorim, Jacileide Guimarães, Olívia Morais de Medeiros Neta, I. G. Amorim, Rafael Otávio Bezerra de Morais
Objective: to analyze mental health in the face of visual impairment, identifying the stages of psychological distress in the encounter with the not seeing. Method: This is an exploratory study with a qualitative approach. Fifteen adults with visual impairment attended at a specialized ophthalmology ambulatory in a university hospital in the city of Natal, Rio Grande do Norte, Brazil were studied, from June to August 2015, through a semistructured interview. The speeches were analyzed based on the theory of mourning. Results: the results showed that the mental health of the visually impaired person is structured through a normative apparatus constituted of individual and social attributes dynamically constructed. These attributes are related to the constitution of stages of mourning, characterized by shock, denial, bargaining, depression, and acceptance. The mental health of the visually impaired person contemplates the phases of normal mourning, established before the condition of visual loss, as structuring mode in a process of personal reconstruction, reflected in the ways of walking the life, proper from each one. Conclusion: With this study, it was possible to understand the ways of constitution and reconstitution of people in dealing with a new condition, the one of visual impairment, providing caregivers, family, and society with an ethical spirit and solidarity, more compliant and humane in the to deal with people with disabilities.
{"title":"Mental health how (re)constitutive tool in ways of living of visually impaired persons","authors":"Érico Gurgel Amorim, Jacileide Guimarães, Olívia Morais de Medeiros Neta, I. G. Amorim, Rafael Otávio Bezerra de Morais","doi":"10.3823/2596","DOIUrl":"https://doi.org/10.3823/2596","url":null,"abstract":"Objective: to analyze mental health in the face of visual impairment, identifying the stages of psychological distress in the encounter with the not seeing. Method: This is an exploratory study with a qualitative approach. Fifteen adults with visual impairment attended at a specialized ophthalmology ambulatory in a university hospital in the city of Natal, Rio Grande do Norte, Brazil were studied, from June to August 2015, through a semistructured interview. The speeches were analyzed based on the theory of mourning. Results: the results showed that the mental health of the visually impaired person is structured through a normative apparatus constituted of individual and social attributes dynamically constructed. These attributes are related to the constitution of stages of mourning, characterized by shock, denial, bargaining, depression, and acceptance. The mental health of the visually impaired person contemplates the phases of normal mourning, established before the condition of visual loss, as structuring mode in a process of personal reconstruction, reflected in the ways of walking the life, proper from each one. Conclusion: With this study, it was possible to understand the ways of constitution and reconstitution of people in dealing with a new condition, the one of visual impairment, providing caregivers, family, and society with an ethical spirit and solidarity, more compliant and humane in the to deal with people with disabilities.","PeriodicalId":73409,"journal":{"name":"International archives of medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70308228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Question: Are Public policies that contemplate intrasectorality capable of producing better results for society, public health and safety? Design: Descriptive study with data analysis from September 2014 to December 2015. Participants: Civil and Military Police of São Paulo State (western region of São Paulo City). Intervention: Analysis of criminal indicators of public health interest in the western region of São Paulo City during the period of applicability of intrasectorality as public health and safety policy. Outcome measures: analysis of the management model and record of reports interesting to public health. The first analysis was carried out in 3 police districts, later spreading to the entire western region of São Paulo City. Qualitative variables were based on the International Code of Diseases (ICD). The quantitative results obtained were extracted from the Criminal Intelligence System. Data were analyzed using descriptive statistics with a significance level of 95%. The software used was the bioestat 5.0 for windows. Results: There was a reduction of 4% to 44% in criminal indicators of public health interest. Conclusion: Intrasectorality was able to improve public health outcomes when used as public policy in police institutions, reducing the impact of violence on public health.
{"title":"Aiming for Intrasectorality: Public Safety and Health","authors":"Luiz Fernando de Lima Paulo, M. Akerman","doi":"10.3823/2595","DOIUrl":"https://doi.org/10.3823/2595","url":null,"abstract":" Question: Are Public policies that contemplate intrasectorality capable of producing better results for society, public health and safety? \u0000 Design: Descriptive study with data analysis from September 2014 to December 2015. \u0000 Participants: Civil and Military Police of São Paulo State (western region of São Paulo City). \u0000 Intervention: Analysis of criminal indicators of public health interest in the western region of São Paulo City during the period of applicability of intrasectorality as public health and safety policy. \u0000 Outcome measures: analysis of the management model and record of reports interesting to public health. The first analysis was carried out in 3 police districts, later spreading to the entire western region of São Paulo City. \u0000 Qualitative variables were based on the International Code of Diseases (ICD). The quantitative results obtained were extracted from the Criminal Intelligence System. \u0000 Data were analyzed using descriptive statistics with a significance level of 95%. The software used was the bioestat 5.0 for windows. \u0000 Results: There was a reduction of 4% to 44% in criminal indicators of public health interest. \u0000 Conclusion: Intrasectorality was able to improve public health outcomes when used as public policy in police institutions, reducing the impact of violence on public health.","PeriodicalId":73409,"journal":{"name":"International archives of medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48856144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aline Marcelino Ramos, E. Barlem, Jamila Geri Tomaschewski Barlem, Laurelize Pereira Rocha, R. D. S. Silveira, Liliane Alves Pereira
Background: By focusing in prioritizing patients and their rights, occasional limitations may arise and prevent nurses from doing their work according to their social and professional commitment. This may culminate in Moral Distress, resulting from the incoherence between the nurses' actions and their personal convictions. Research question: Is there any relationship between healthcare advocacy and moral distress in the practice of nurses working in hospitals? Objective: Analyzing the relation between healthcare advocacy and moral distress in the practice of nurses working in hospitals. Research design: Quantitative, analytical cross-sectional study. The data collection instruments comprise the Moral Distress Scale Revised – Brazilian version and the Protective Nursing Advocacy Scale – Brazilian version. Data analysis was carried out with elements of descriptive statistics, Pearson's correlation and linear regression analysis. Participants and research context: The participants comprised 157 nurses working in two hospitals located in a city in southern Brazil. One of the institutions is a public university hospital and the other is a philanthropic institution. Ethical considerations: All the international directives for research with human beings were observed. Findings: The constructs barriers to the advocacy practice and negative implications to the advocacy practice were pointed out as predictors of moral distress. Discussion: The situations approached in this study illustrate that certain organizational and cultural contexts have negative impacts on nurses, who are in constant contact with the necessity of promoting patient well being and increasing access to healthcare, especially under the perception of vulnerability in risk situations, or when the quality of the services provided decreases and patients are not given adequate assistance. Conclusion: We hope that this study encourages the reflection about the relationship between patient advocacy and moral distress, and the search for resources that may contribute to the quality of the assistance provided by nurses.
{"title":"Healthcare Advocacy And Moral Distress In The Practice Of Nurses","authors":"Aline Marcelino Ramos, E. Barlem, Jamila Geri Tomaschewski Barlem, Laurelize Pereira Rocha, R. D. S. Silveira, Liliane Alves Pereira","doi":"10.3823/2578","DOIUrl":"https://doi.org/10.3823/2578","url":null,"abstract":"Background: By focusing in prioritizing patients and their rights, occasional limitations may arise and prevent nurses from doing their work according to their social and professional commitment. This may culminate in Moral Distress, resulting from the incoherence between the nurses' actions and their personal convictions. \u0000Research question: Is there any relationship between healthcare advocacy and moral distress in the practice of nurses working in hospitals? \u0000Objective: Analyzing the relation between healthcare advocacy and moral distress in the practice of nurses working in hospitals. \u0000Research design: Quantitative, analytical cross-sectional study. The data collection instruments comprise the Moral Distress Scale Revised – Brazilian version and the Protective Nursing Advocacy Scale – Brazilian version. Data analysis was carried out with elements of descriptive statistics, Pearson's correlation and linear regression analysis. \u0000Participants and research context: The participants comprised 157 nurses working in two hospitals located in a city in southern Brazil. One of the institutions is a public university hospital and the other is a philanthropic institution. \u0000Ethical considerations: All the international directives for research with human beings were observed. \u0000Findings: The constructs barriers to the advocacy practice and negative implications to the advocacy practice were pointed out as predictors of moral distress. \u0000Discussion: The situations approached in this study illustrate that certain organizational and cultural contexts have negative impacts on nurses, who are in constant contact with the necessity of promoting patient well being and increasing access to healthcare, especially under the perception of vulnerability in risk situations, or when the quality of the services provided decreases and patients are not given adequate assistance. \u0000Conclusion: We hope that this study encourages the reflection about the relationship between patient advocacy and moral distress, and the search for resources that may contribute to the quality of the assistance provided by nurses.","PeriodicalId":73409,"journal":{"name":"International archives of medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43870330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nowadays, depression in adolescents is understood to be a common, disabling and recurrent disease, with a high level of morbidity and mortality. Thus, it is an important public health problem. Suicide is the act of intentionally ending one’s own life. It is related to biological, social, environmental factors and to the personal history, so, is a complex and multifactor phenomenon. The lack of research and literature with this population hinders the comprehension of the phenomenon and so the improvement of interventions in the field of prevention and care for survivors. This paper reviews on clinical and epidemiological aspects of suicide in Children, definitions and expressions of suicide among adolescents people are presented, identifying possible risk factors and prevention interventions are discussed.
{"title":"Suicide in Children and adolescents: a review of articles about this topic","authors":"B. Viana, Fabiana Gouveia Guimarães, C. Silva","doi":"10.3823/2564","DOIUrl":"https://doi.org/10.3823/2564","url":null,"abstract":"Nowadays, depression in adolescents is understood to be a common, disabling and recurrent disease, with a high level of morbidity and mortality. Thus, it is an important public health problem. Suicide is the act of intentionally ending one’s own life. It is related to biological, social, environmental factors and to the personal history, so, is a complex and multifactor phenomenon. The lack of research and literature with this population hinders the comprehension of the phenomenon and so the improvement of interventions in the field of prevention and care for survivors. This paper reviews on clinical and epidemiological aspects of suicide in Children, definitions and expressions of suicide among adolescents people are presented, identifying possible risk factors and prevention interventions are discussed. \u0000 ","PeriodicalId":73409,"journal":{"name":"International archives of medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47949467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joelma Gonçalves, M. B. Martins, M. L. L. Buril, J. Aguiar, Terezinha Gonçalves Da Silva, T. G. Souza, N. P. Santos, C. Chagas, E. Pereira, Emerson P. S. Falcão, N. H. Silva
Background: Secondary metabolites are responsible for most of the biological activities of lichens. Many of these compounds exhibit significant antineoplastic activity. The aim of the present in vitro study was to evaluate the cytotoxic and genotoxic activities of organic extracts and purified barbatic acid from the lichen Cladonia salzmannii (Nyl.). Methods: The thallus of the lichen (22 g) was cleaned and dried with the solvents diethyl ether, chloroform and acetone. Organic extracts were obtained using the hot exhausted method in a Soxhlet apparatus. Barbatic acid (BAR) was purified from the ether extract (1.3 g). Chemical analysis of the organic extracts and purified BAR was performed using thin-layer chromatography. The purity of purified BAR was determined using high-performance liquid chromatography. The MTT method [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] and cytokinesis-block proliferation index (CBPI) were used to determine the cytotoxic activity of the organic extracts and purified BAR. The micronucleus test and comet assay were used to determine genotoxic potential of the organic extracts and purified BAR. Dimethyl sulfoxide was used as the diluting solvent of the samples in all biological tests. Results: The IC50 results demonstrated significant cytotoxic potential of the ether extract (50 µg/mL) against cell lines NCI-H292 (IC50: 29.91 µg/mL), HEp-2 (IC50: 26.75 µg/mL) and HL-60 (IC50: 3.59 µg/mL) as well as the purified BAR (25 µg/mL) against cell lines HEp-2 (IC50: 15.79 µg/mL) and MCF-7 (IC50: 18.28 µg/mL). The CBPI demonstrated the cytotoxic activity of the purified BAR at all concentrations tested (5, 10, 20 and 40 µg/mL) and all organic extracts (50 µg/mL) against Ehrlich carcinoma cells. For sarcoma 180, only BAR purified at a concentration of 40 µg/mL and the ether and chloroform extracts (50 µg/mL) were considered cytotoxic. The micronucleus test revealed that the purified BAR at a concentration of 5 µg/mL had no genotoxic potential against either tumor cell line. Furthermore, the chloroform extract and purified BAR at a concentration of 10 µg/mL were not considered genotoxic for sarcoma 180. In the comet assay, all compounds tested induced DNA damage in both tumor lines. Conclusion: Based on the present results, organic extracts and purified barbatic acid from C. salzmannii exhibit cytotoxic and genotoxic activity against of the tumor cell lines tested.
{"title":"Antineoplastic Activity and Genotoxicity of Organic Extracts and Barbatic Acid Isolated from the Lichen Cladonia salzmannii Nyl","authors":"Joelma Gonçalves, M. B. Martins, M. L. L. Buril, J. Aguiar, Terezinha Gonçalves Da Silva, T. G. Souza, N. P. Santos, C. Chagas, E. Pereira, Emerson P. S. Falcão, N. H. Silva","doi":"10.3823/2594","DOIUrl":"https://doi.org/10.3823/2594","url":null,"abstract":"Background: Secondary metabolites are responsible for most of the biological activities of lichens. Many of these compounds exhibit significant antineoplastic activity. The aim of the present in vitro study was to evaluate the cytotoxic and genotoxic activities of organic extracts and purified barbatic acid from the lichen Cladonia salzmannii (Nyl.). \u0000Methods: The thallus of the lichen (22 g) was cleaned and dried with the solvents diethyl ether, chloroform and acetone. Organic extracts were obtained using the hot exhausted method in a Soxhlet apparatus. Barbatic acid (BAR) was purified from the ether extract (1.3 g). Chemical analysis of the organic extracts and purified BAR was performed using thin-layer chromatography. The purity of purified BAR was determined using high-performance liquid chromatography. The MTT method [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] and cytokinesis-block proliferation index (CBPI) were used to determine the cytotoxic activity of the organic extracts and purified BAR. The micronucleus test and comet assay were used to determine genotoxic potential of the organic extracts and purified BAR. Dimethyl sulfoxide was used as the diluting solvent of the samples in all biological tests. \u0000Results: The IC50 results demonstrated significant cytotoxic potential of the ether extract (50 µg/mL) against cell lines NCI-H292 (IC50: 29.91 µg/mL), HEp-2 (IC50: 26.75 µg/mL) and HL-60 (IC50: 3.59 µg/mL) as well as the purified BAR (25 µg/mL) against cell lines HEp-2 (IC50: 15.79 µg/mL) and MCF-7 (IC50: 18.28 µg/mL). The CBPI demonstrated the cytotoxic activity of the purified BAR at all concentrations tested (5, 10, 20 and 40 µg/mL) and all organic extracts (50 µg/mL) against Ehrlich carcinoma cells. For sarcoma 180, only BAR purified at a concentration of 40 µg/mL and the ether and chloroform extracts (50 µg/mL) were considered cytotoxic. The micronucleus test revealed that the purified BAR at a concentration of 5 µg/mL had no genotoxic potential against either tumor cell line. Furthermore, the chloroform extract and purified BAR at a concentration of 10 µg/mL were not considered genotoxic for sarcoma 180. In the comet assay, all compounds tested induced DNA damage in both tumor lines. \u0000Conclusion: Based on the present results, organic extracts and purified barbatic acid from C. salzmannii exhibit cytotoxic and genotoxic activity against of the tumor cell lines tested.","PeriodicalId":73409,"journal":{"name":"International archives of medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48351824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: One must take into account the conditions that develop the lives of several women who are at risk, above all, in terms of mental health. In addition, Latin American countries dominate the 10 ranking on feminicide. Objective: To understand the chaotic scenario that haunts the reality of many women around the world. Dark, bloody and restrained are common adjectives to the silent daily suffering they experience. Results: In general, there’s also a reluctance in some communities to acknowledge violence against women as a problem. Thus, it is noted that such taboos make it difficult to debate the topic. As a consequence, the chauvinism culture silences an already voiceless problem because of the lack of financial support experienced by these women to raise their children. At this stage, demanding justice and upholding the law guaranteeing the right to life of all citizens often seems to be the only way to punish the perpetrators of these women. Limitations: Although it is a current theme, faced with the situational framework, it is difficult to find evidence about this aspect, it's important to highlight that those vulnerability factors are also risk factors for mental health disorders following assault. It was found that factors such as age, personal characteristics such as the life history of each person, involvement with self-mutilation, participation and support in mental or social services suggest to be more important than the type of aggression as predictors of mental disorders health. Conclusion: At first sight it seems that it is impossible to give what you do not have for someone who does not want to, but this is only a psychological contradiction if you consider indifference and love, or anger and love, or hatred and love as opposing feelings, as long as those feelings can exist simultaneously. It is necessary for society to reclaim humanity for women to exercise freedom. Because based on what was seen are still cultural patterns, like misogyny, discrimination and the ideal of male superiority that support the guilty of the assaulted rather than the aggressor.
{"title":"Feminicide, Women's Bodies and Impunity","authors":"C. F. Freitas, M. Neto","doi":"10.3823/2592","DOIUrl":"https://doi.org/10.3823/2592","url":null,"abstract":"Background: One must take into account the conditions that develop the lives of several women who are at risk, above all, in terms of mental health. In addition, Latin American countries dominate the 10 ranking on feminicide. \u0000Objective: To understand the chaotic scenario that haunts the reality of many women around the world. Dark, bloody and restrained are common adjectives to the silent daily suffering they experience. \u0000Results: In general, there’s also a reluctance in some communities to acknowledge violence against women as a problem. Thus, it is noted that such taboos make it difficult to debate the topic. As a consequence, the chauvinism culture silences an already voiceless problem because of the lack of financial support experienced by these women to raise their children. At this stage, demanding justice and upholding the law guaranteeing the right to life of all citizens often seems to be the only way to punish the perpetrators of these women. \u0000Limitations: Although it is a current theme, faced with the situational framework, it is difficult to find evidence about this aspect, it's important to highlight that those vulnerability factors are also risk factors for mental health disorders following assault. It was found that factors such as age, personal characteristics such as the life history of each person, involvement with self-mutilation, participation and support in mental or social services suggest to be more important than the type of aggression as predictors of mental disorders health. \u0000Conclusion: At first sight it seems that it is impossible to give what you do not have for someone who does not want to, but this is only a psychological contradiction if you consider indifference and love, or anger and love, or hatred and love as opposing feelings, as long as those feelings can exist simultaneously. It is necessary for society to reclaim humanity for women to exercise freedom. Because based on what was seen are still cultural patterns, like misogyny, discrimination and the ideal of male superiority that support the guilty of the assaulted rather than the aggressor.","PeriodicalId":73409,"journal":{"name":"International archives of medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46758833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. B. Barros, Polliany Ribeiro de Quadros, Karlla Lorenna dos Santos Anjos, N. Chaves, Wanessa Costa Silva, J. C. Souza, A. Campos, Marcela Bianca Lima Santos, Thais Martins Novaes, Nathasha Nunes Ribeiro, Bruna Vaz Pereira Rodrigues, A. Feio, Erica Gomes do Nascimento Cavalcante
Objective: This study aims to evaluate socioeconomic profile, practice and knowledge of mothers of children up to 2 years old on breastfeeding and complementary feeding. Methods: interviews applied to 104 mothers who were subjected to research protocol consists of 33 questions on breastfeeding, complementary feeding, sociodemographic and obstetrical data. Results: most mothers were between 20 and 34 years old, was in a stable union, had completed high school, was unemployed, was subjected to caesarean operation, and attended six or more prenatal consultations. Regarding breastfeeding and complementary feeding mothers had good knowledge of the subject and demonstrated practice properly on most issues. Conclusion: results highlight the need for studies on the causes of differences between practice and knowledge about breastfeeding and complementary feeding, analyzing the received prenatal and failures or absence of post-natal care in to clarify and assist the practical questions of mothers
{"title":"Breastfeeding and complementary feeding: Practice, knowledge and socioeconomic profile of mothers of children up to 2 years of age at a Health School of Pará","authors":"L. B. Barros, Polliany Ribeiro de Quadros, Karlla Lorenna dos Santos Anjos, N. Chaves, Wanessa Costa Silva, J. C. Souza, A. Campos, Marcela Bianca Lima Santos, Thais Martins Novaes, Nathasha Nunes Ribeiro, Bruna Vaz Pereira Rodrigues, A. Feio, Erica Gomes do Nascimento Cavalcante","doi":"10.3823/2593","DOIUrl":"https://doi.org/10.3823/2593","url":null,"abstract":"Objective: This study aims to evaluate socioeconomic profile, practice and knowledge of mothers of children up to 2 years old on breastfeeding and complementary feeding. \u0000Methods: interviews applied to 104 mothers who were subjected to research protocol consists of 33 questions on breastfeeding, complementary feeding, sociodemographic and obstetrical data. \u0000Results: most mothers were between 20 and 34 years old, was in a stable union, had completed high school, was unemployed, was subjected to caesarean operation, and attended six or more prenatal consultations. Regarding breastfeeding and complementary feeding mothers had good knowledge of the subject and demonstrated practice properly on most issues. \u0000Conclusion: results highlight the need for studies on the causes of differences between practice and knowledge about breastfeeding and complementary feeding, analyzing the received prenatal and failures or absence of post-natal care in to clarify and assist the practical questions of mothers","PeriodicalId":73409,"journal":{"name":"International archives of medicine","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42282945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：