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Advances in neurology最新文献

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The natural history of multiple sclerosis. 多发性硬化症的自然史。
Advances in neurology
Pub Date : 2006-01-01
Rajas Deshpande, Marcelo Kremenchutzky, George P A Rice
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引用次数: 0
Genes and Tourette syndrome: scientific, ethical, and social implications. 基因和抽动秽语综合征:科学、伦理和社会影响。
Advances in neurology
Pub Date : 2006-01-01
Nancy M P King
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引用次数: 0
Attention deficit hyperactivity disorder, chronic tic disorder, and methylphenidate. 注意缺陷多动障碍，慢性抽动障碍和哌醋甲酯。
Advances in neurology
Pub Date : 2006-01-01
Kenneth D Gadow, Jeffrey Sverd
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引用次数: 0
The use of glatiramer acetate in the treatment of multiple sclerosis. 醋酸格拉替默在多发性硬化治疗中的应用。
Advances in neurology
Pub Date : 2006-01-01
Jerry S Wolinsky

Glatiramer acetate is a collection of synthetic polypeptides indicated as therapy for relapsing a remitting multiple sclerosis (MS). Current understanding of the immunological and neuroprotective mechanisms of action of GA makes it unique among current MS therapies. The clinical efficacy of GA appears similar to that of the recombinant beta interferons. GA has a favorable side effect profile with excellent patient compliance and long-term acceptance. The results of pivotal controlled clinical trials and long-term data derived from organized extension studies are reviewed. Supportive data from open-label comparison, combination treatment and therapeutic switch studies are also provided to enable informed decisions on the appropriate place for GA among other immunomodulatory treatments for relapsing MS.

醋酸格拉替默是一种合成多肽的集合，用于治疗复发的缓解型多发性硬化症(MS)。目前对GA作用的免疫和神经保护机制的了解使其在当前的MS治疗中独树一帜。GA的临床疗效与重组干扰素相似。GA具有良好的副作用，具有良好的患者依从性和长期接受性。本文回顾了关键对照临床试验的结果和来自有组织的扩展研究的长期数据。来自开放标签比较、联合治疗和治疗转换研究的支持性数据也提供了，以便在其他免疫调节治疗复发性多发性硬化症的适当位置上做出明智的决定。
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引用次数: 0
Tics associated with other disorders. 抽搐与其他疾病有关。
Advances in neurology
Pub Date : 2006-01-01
Joseph Jankovic, Nicte I Mejia
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引用次数: 0
Web-based consensus diagnosis for genetics studies of Gilles de la Tourette syndrome. 基于网络的图雷特综合征遗传学研究共识诊断。
Advances in neurology
Pub Date : 2006-01-01
William M McMahon, Cornelia L Illmann, Meghan M McGinn
{"title":"Web-based consensus diagnosis for genetics studies of Gilles de la Tourette syndrome.","authors":"William M McMahon,&nbsp;Cornelia L Illmann,&nbsp;Meghan M McGinn","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7356,"journal":{"name":"Advances in neurology","volume":"99 ","pages":"136-43"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25903767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of tics. 抽搐的治疗。
Advances in neurology
Pub Date : 2006-01-01
Leon S Dure, Jennifer DeWolfe
{"title":"Treatment of tics.","authors":"Leon S Dure,&nbsp;Jennifer DeWolfe","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7356,"journal":{"name":"Advances in neurology","volume":"99 ","pages":"191-6"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25903774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Behavioral neurosurgery. 行为神经外科。
Advances in neurology
Pub Date : 2006-01-01
Donald A Malone, Mayur M Pandya
{"title":"Behavioral neurosurgery.","authors":"Donald A Malone,&nbsp;Mayur M Pandya","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7356,"journal":{"name":"Advances in neurology","volume":"99 ","pages":"241-7"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25905948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcome measures in intractable epilepsy. 难治性癫痫的结局指标。
Advances in neurology
Pub Date : 2006-01-01
Samuel Wiebe
{"title":"Outcome measures in intractable epilepsy.","authors":"Samuel Wiebe","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7356,"journal":{"name":"Advances in neurology","volume":"97 ","pages":"11-5"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25774384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Participation of cortical glial cells to the genesis of spike-wave seizures. 皮质胶质细胞参与尖波发作的发生。
Advances in neurology
Pub Date : 2006-01-01
Florin Amzica
{"title":"Participation of cortical glial cells to the genesis of spike-wave seizures.","authors":"Florin Amzica","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":7356,"journal":{"name":"Advances in neurology","volume":"97 ","pages":"173-82"},"PeriodicalIF":0.0,"publicationDate":"2006-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25774400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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