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Can Plasma Volume Affect Arterial Stiffness and Autonomic Modulation Response to Resistance Exercise? 血浆容量会影响动脉僵硬度和自主调节对阻力运动的反应吗?
Pub Date : 2019-07-11 DOI: 10.19080/jocct.2019.14.555883
D. Rodriguez
Introduction : Despite the numerous benefits of resistance exercise (RE), stress caused by muscle contractions may cause transient disturbances in the cardiovascular system including arterial stiffness increasing the temporary risk of cardiovascular events. One physiological response which can influence this process but has received little attention from the scientific community is plasma volume (PV). Discussion : Recent reviews point to a complex interaction between autonomic modulation, central and peripheral adjustments triggered by a RE session. After the end of a moderate to high intensity RE session there may be a reduction in PV caused by its influx into the interstitial tissue and consequent decline in stroke volume and venous return. Moreover, there is an increase in sympathetic modulation, and a decrease in parasympathetic modulation. Arterial stiffness is one of the first signs of pathological changes in the arterial wall leading to an increased risk of cardiovascular events. The stiffening of the main arteries of the body can also be negatively affected by PV reduction. The PV reduction would lead to elevation of sympathetic nerve modulation, cardiac workload and reduction in cardiac perfusion. However, depending of the nature of the PV reduction contradictory results emerges and decrease in arterial stiffness was also reported. Conclusion : There is no agreement as to why PV reduction may affect arterial stiffness, and several questions regarding hydration status and RE influence remains to be addressed. Future studies should standardize water intake and control hydration status before and during experimental sessions utilizing simple measures of hydration status.
简介:尽管阻力运动(RE)有很多好处,但肌肉收缩引起的压力可能会导致心血管系统的短暂紊乱,包括动脉僵硬,增加心血管事件的暂时风险。影响这一过程的一种生理反应是等离子体体积(PV),但很少受到科学界的关注。讨论:最近的评论指出自主神经调节、中枢和外周调节之间的复杂相互作用是由RE会话触发的。在中度至高强度RE治疗结束后,PV可能因其流入间质组织而减少,从而导致卒中容量和静脉回流下降。此外,交感神经调节增加,副交感神经调节减少。动脉僵硬是动脉壁病理改变的第一个迹象,导致心血管事件的风险增加。主干动脉的硬化也会受到PV降低的负面影响。PV减少会导致交感神经调节升高,心脏负荷增加,心脏灌注减少。然而,根据PV减少的性质,出现了矛盾的结果,动脉僵硬度也有所下降。结论:关于PV降低可能影响动脉僵硬的原因尚未达成一致,关于水合状态和RE影响的几个问题仍有待解决。未来的研究应该在实验前和实验期间使用简单的水合状态测量来规范水的摄入量和控制水合状态。
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引用次数: 0
A Rare Case of Secundum Atrial Septal Defect with Intractable Heart Failure after Coarctectomy by an Infant 婴儿房间隔切除术后继发性房间隔缺损并发顽固性心力衰竭1例
Pub Date : 2019-07-10 DOI: 10.19080/jocct.2019.14.555882
Z. Vassileva
We present a case of resistant to medical treatment heart failure due to significant shunting through a secundum atrial septal defect by a 3-month old infant who underwent coarctectomy due to critical coarctation of the aorta at the age of 15 days. The tachydyspnea and failure to thrive persisted despite the successful resection of the coarctation and resolved very rapidly after subsequent operative closure of the atrial septal defect.
我们报告了一例因一名3个月大的婴儿在15天大时因主动脉严重缩窄而接受缩窄切除术,导致其通过继发性房间隔缺损进行显著分流,从而导致对药物治疗产生耐药性的心力衰竭。尽管成功切除了缩窄,但快速呼吸困难和发育不良仍然存在,并在随后的房间隔缺损手术闭合后迅速缓解。
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引用次数: 0
Arrhythmogenic Nitro-Oxidative Stress: A Working Hypothesis in Chagas’ Heart Disease 致心律失常的硝基氧化应激:恰加斯心脏病的一个有效假说
Pub Date : 2019-07-08 DOI: 10.19080/jocct.2019.14.555881
R. Pedrosa
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引用次数: 0
Late, but Before Schedule-A Bigeminal Rhythm with Blocked Premature Junctional Beats 晚但早于时间表——伴早搏阻滞的双联节律
Pub Date : 2019-07-05 DOI: 10.19080/jocct.2019.14.555880
Daniel Manna
Premature supraventricular ectopic beats are common findings in ambulatory ECG monitoring. Blocked ectopic beats may occur if the premature beat coincides with the refractory period of the downstream conductive tissues. We report of an uncommon, symptomatic bigeminal rhythm which resulted in an abrupt decrease of the heart rate because of blocked P waves. The blocked P waves appeared uncommonly late in the cardiac cycle because of a very His-near activation site. For anatomic reasons treatment was difficult and the patient received a pacemaker.
室上早搏是动态心电图监测中常见的表现。如果早搏与下游传导组织的不应期重合,则可能发生阻塞性异位搏动。我们报告了一种罕见的症状性双联律,由于P波阻断导致心率突然下降。阻塞的P波在心动周期后期出现,这是罕见的,因为His的激活位点非常接近。由于解剖原因,治疗很困难,患者接受了起搏器。
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引用次数: 0
Is the risk of Delirium reduced in Minimal Invasive Cardiac Surgery 微创心脏手术是否降低了谵妄的风险
Pub Date : 2019-06-19 DOI: 10.19080/jocct.2019.14.555879
J. ChaudGermán
Background: The number of cardiac operations is steadily increasing in industrialized countries, being Delirium one of the most frequent postoperative complications. Aortic Valve Replacement by mini-invasive surgery has reported to offer innumerable benefits over Complete Sternotomy, such as better esthetic, less surgical trauma, pain, blood and postoperative complications, a functional recovery and a shorter hospital stay. Objectives: To determine the frequency of Delirium and to identify its risk factors in patients undergoing mini-sternotomy (MS) versus full sternotomy (FS) isolated aortic valve replacement (AVR). Methods: An interdisciplinary, descriptive and retrospective study of 113 adults patients who underwent an Isolated Aortic Valve Replacement (AVR) with mini-sternotomy (MS) and full sternotomy (FS) was conducted. Variables related to delirium were characterized as being present before, during or after cardiac surgery. Results: Delirium occurred in 26 patients (23%). In the MS group, 12 patients (25%) had Delirium while 36 (75%) had no Delirium. In the FS group, 14 (21.5%) patients had Delirium whereas 51 did not have it (78.5%) and P: 0.66. Regarding to valve type among Delirium patients, 5 had a mechanical one while 21 patients with a biological valve. P: 0.02. Late extubation had 7 (6.2%) patients in the Delirium group versus 1 (9%) in the non-Delirium group. P: 0.001. Postoperative Hb analysis revealed an average of 9.2mg/dL and 9.8mg/dl for Delirium and non - Delirum patients respectively. P: 0.05. Renal disease was showed in 8 (7.1%) patients in the Delirium group versus 4 in the No delirium group (3.5%) with a P value of 0.001. No mortality event has been registered in any of the groups. Conclusion: MS has shown numerous advantages over conventional surgery before this study, nevertheless the risk of Delirium has not been previously assessed in this context. The risk factors and an increasing frequency of Delirium should be taking into account due to its high morbidity rate and significant cost of the health system.
背景:在工业化国家,心脏手术的数量正在稳步增加,谵妄是最常见的术后并发症之一。据报道,微创手术替代主动脉瓣比完全性Sternotomy有无数好处,如更好的美观、更少的手术创伤、疼痛、血液和术后并发症、功能恢复和更短的住院时间。目的:确定小胸骨切开术(MS)与全胸骨切开术与单纯主动脉瓣置换术(AVR)患者发生谵妄的频率,并确定其危险因素。方法:对113名成人患者进行跨学科、描述性和回顾性研究,这些患者接受了小胸骨切开术(MS)和全胸骨切除术(FS)的孤立性主动脉瓣置换术(AVR)。与谵妄相关的变量被描述为在心脏手术之前、期间或之后存在。结果:26例(23%)患者发生谵妄。在MS组中,12名患者(25%)患有谵妄,36名患者(75%)没有谵妄。FS组中,14名(21.5%)患者患有谵妄,而51名患者没有谵妄(78.5%),P:0.66。关于Delirium患者的瓣膜类型,5名患者使用机械瓣膜,21名患者使用生物瓣膜。P: 0.02。谵妄组有7名(6.2%)患者延迟拔管,而非谵妄组则有1名(9%)患者。P: 0.001。术后Hb分析显示,谵妄和非谵妄患者的平均Hb分别为9.2mg/dL和9.8mg/dL。P: 0.05。谵妄组有8名(7.1%)患者出现肾脏疾病,非谵妄组为4名(3.5%),P值为0.001。在任何一组中都没有登记死亡事件。结论:在本研究之前,多发性硬化症已显示出优于传统手术的许多优势,但之前尚未在这方面评估谵妄的风险。由于谵妄的发病率高,卫生系统成本高,因此应考虑其风险因素和发病频率的增加。
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引用次数: 1
Evaluation of P wave Dispersion before and after Thrombolytic Therapy 溶栓治疗前后P波离散度的评价
Pub Date : 2019-06-04 DOI: 10.19080/jocct.2019.14.555878
Samir M Rafla
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引用次数: 0
First Experience with Cryo-Balloon Ablation of Atrial Fibrillation. A Case Report 心房颤动冷冻球囊消融的首次经验。案例报告
Pub Date : 2019-05-24 DOI: 10.19080/jocct.2019.14.555877
Samir M Rafla
We compared the efficacy and safety of radiofrequency with cryothermal energy in catheter ablation of patients with paroxysmal AF. The study included 24 consecutive patients with highly symptomatic paroxysmal AF (PAF) refractory to at least 1 class of antiarrhythmic drugs. Group I radiofrequency ablation and group II cryoballoon ablation (each group consists of 12 patients). Exclusion criteria: Patients <18 years, Structural heart disease (hypertrophic cardiomyopathy, left ventricular ejection fraction < 35%, significant valvular heart disease, LA size >50 mm), reversible causes of AF, intracardiac thrombus, inability to take oral anticoagulants, additional ablation lines other than cavotricuspid isthmus (CTI) and Repeat AF ablation. Transseptal puncture was performed under fluoroscopic guidance, one for the cryoballoon and two for the RF ablation.
我们比较了冷冻能射频消融阵发性房颤(PAF)的有效性和安全性。该研究包括24例对至少1类抗心律失常药物难治性的高症状阵发性房颤(PAF)患者。第一组射频消融,第二组低温球囊消融(每组12例)。排除标准:患者50mm),房颤的可逆性原因,心内血栓,不能服用口服抗凝剂,除caavotricuspid峡(CTI)以外的其他消融线和重复房颤消融。在透视引导下进行经间隔穿刺,一次用于低温球囊,两次用于射频消融。
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引用次数: 0
The Effect of Timing of Percutaneous Coronary Intervention Following Thrombolytic Therapy on the Outcome of Patients Presenting with ST Segment Elevation Myocardial Infarction 溶栓治疗后经皮冠状动脉介入治疗时机对ST段抬高型心肌梗死患者预后的影响
Pub Date : 2019-05-14 DOI: 10.19080/jocct.2019.13.555875
Ahmad M Alkonaissi
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引用次数: 0
Dilated Cardiomyopathy is a Risk in Junctional Epidermolysis Bullosa 扩张型心肌病是大疱性结缔组织表皮松解症的危险因素
Pub Date : 2019-04-24 DOI: 10.19080/jocct.2019.13.555873
F. Mostafa
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引用次数: 1
Correlation between Intravascular Ultrasound and Multi-Detector Computed Tomography in Assessment of Coronary Lesion in Patients with Ischemic Heart Disease 血管内超声与多探测器计算机断层扫描在评估缺血性心脏病患者冠状动脉病变中的相关性
Pub Date : 2019-04-18 DOI: 10.19080/jocct.2019.13.555871
H. Ebaid
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引用次数: 0
期刊
Journal of cardiology & cardiovascular therapy
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