Background: Titanium (TI) and yttria stabilized-zirconia oxide (YSZ) are dental materials commonly utilized at the soft-tissue interface surrounding dental implants. The influence of these surfaces on bacterial adhesion and biofilm development may affect clinical performance and patient susceptibility to inflammatory peri-implant disease. The purpose of this study was to evaluate the influence of the substrate material on biofilm diversity. Methods: Biofilms were cultured on TI, YSZ, and hydroxyapatite (HA) surfaces (control) using plaque specimens obtained from three human donors. Duplicate cultures grew for one, two, three, six or nine days. Biofilm diversity was then analyzed using 16S rRNA sequencing. The Shannon Diversity Index (SDI) was calculated for each experimental group. Microbial profiles were intercompared in a pairwise fashion to establish dissimilarity scores, which were recorded in a distance dissimilarity matrix. Results: A total of 16 taxa were identified, and relative abundances of the predominant phyla and genera did not appear statistically different across experimental groups. Biofilms grown on HA surfaces exhibited significantly higher alpha diversity compared with those formed on TI or YSZ (p<0.0001), although biofilms cultured on TI and YSG surfaces exhibited comparable diversity. Statistically significant differences in beta diversity associated with substrate (p=0.012) and growth period (p=0.001) were detected. Conclusions: Under the conditions described, biofilms grown on TI or YSZ appeared significantly less complex than those formed on HA. Transmucosal implant abutment surface characteristics represent one modifiable factor potentially influencing risk of peri-implant disease. Among risk of peri-implant disease. Among multiple considerations in abutment design, biofilm diversity performance may represent a clinically relevant benchmark.
背景：钛（TI）和钇稳定氧化锆（YSZ）是牙科种植体周围软组织界面常用的牙科材料。这些表面对细菌粘附和生物膜发展的影响可能会影响临床表现和患者对种植体周围炎症性疾病的易感性。本研究旨在评估基底材料对生物膜多样性的影响。方法：使用从三位人体捐献者处获得的斑块标本，在TI、YSZ和羟基磷灰石（HA）表面（对照）上培养生物膜。重复培养物分别生长一、二、三、六或九天。然后使用 16S rRNA 测序分析生物膜的多样性。计算每个实验组的香农多样性指数（SDI）。以成对方式相互比较微生物概况，以确定差异分数，并将其记录在距离差异矩阵中。结果共鉴定出 16 个类群，各实验组主要门类和属的相对丰度没有统计学差异。与在 TI 或 YSZ 表面上形成的生物膜相比，生长在 HA 表面上的生物膜显示出明显更高的α多样性（p<0.0001），尽管在 TI 和 YSG 表面上培养的生物膜显示出相当的多样性。贝塔多样性与基质（p=0.012）和生长期（p=0.001）的差异具有统计学意义。结论在所述条件下，生长在 TI 或 YSZ 上的生物膜的复杂性明显低于在 HA 上形成的生物膜。经粘膜种植体基台表面特征是潜在影响种植体周围疾病风险的一个可改变因素。在种植体周围疾病的风险中在基台设计的多个考虑因素中，生物膜多样性的表现可能是与临床相关的基准。
{"title":"The Influence of Hydroxyapatite, Titanium, and Yttria-Stabilized Zirconia Oxide on Diversity of Bacterial Cultures Grown from Human Dental Biofilm Specimens in an In Vitro Model","authors":"","doi":"10.54289/jdoe2400103","DOIUrl":"https://doi.org/10.54289/jdoe2400103","url":null,"abstract":"Background: Titanium (TI) and yttria stabilized-zirconia oxide (YSZ) are dental materials commonly utilized at the soft-tissue interface surrounding dental implants. The influence of these surfaces on bacterial adhesion and biofilm development may affect clinical performance and patient susceptibility to inflammatory peri-implant disease. The purpose of this study was to evaluate the influence of the substrate material on biofilm diversity. Methods: Biofilms were cultured on TI, YSZ, and hydroxyapatite (HA) surfaces (control) using plaque specimens obtained from three human donors. Duplicate cultures grew for one, two, three, six or nine days. Biofilm diversity was then analyzed using 16S rRNA sequencing. The Shannon Diversity Index (SDI) was calculated for each experimental group. Microbial profiles were intercompared in a pairwise fashion to establish dissimilarity scores, which were recorded in a distance dissimilarity matrix. Results: A total of 16 taxa were identified, and relative abundances of the predominant phyla and genera did not appear statistically different across experimental groups. Biofilms grown on HA surfaces exhibited significantly higher alpha diversity compared with those formed on TI or YSZ (p<0.0001), although biofilms cultured on TI and YSG surfaces exhibited comparable diversity. Statistically significant differences in beta diversity associated with substrate (p=0.012) and growth period (p=0.001) were detected. Conclusions: Under the conditions described, biofilms grown on TI or YSZ appeared significantly less complex than those formed on HA. Transmucosal implant abutment surface characteristics represent one modifiable factor potentially influencing risk of peri-implant disease. Among risk of peri-implant disease. Among multiple considerations in abutment design, biofilm diversity performance may represent a clinically relevant benchmark.","PeriodicalId":73703,"journal":{"name":"Journal of dentistry and oral epidemiology","volume":"93 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139784393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Titanium (TI) and yttria stabilized-zirconia oxide (YSZ) are dental materials commonly utilized at the soft-tissue interface surrounding dental implants. The influence of these surfaces on bacterial adhesion and biofilm development may affect clinical performance and patient susceptibility to inflammatory peri-implant disease. The purpose of this study was to evaluate the influence of the substrate material on biofilm diversity. Methods: Biofilms were cultured on TI, YSZ, and hydroxyapatite (HA) surfaces (control) using plaque specimens obtained from three human donors. Duplicate cultures grew for one, two, three, six or nine days. Biofilm diversity was then analyzed using 16S rRNA sequencing. The Shannon Diversity Index (SDI) was calculated for each experimental group. Microbial profiles were intercompared in a pairwise fashion to establish dissimilarity scores, which were recorded in a distance dissimilarity matrix. Results: A total of 16 taxa were identified, and relative abundances of the predominant phyla and genera did not appear statistically different across experimental groups. Biofilms grown on HA surfaces exhibited significantly higher alpha diversity compared with those formed on TI or YSZ (p<0.0001), although biofilms cultured on TI and YSG surfaces exhibited comparable diversity. Statistically significant differences in beta diversity associated with substrate (p=0.012) and growth period (p=0.001) were detected. Conclusions: Under the conditions described, biofilms grown on TI or YSZ appeared significantly less complex than those formed on HA. Transmucosal implant abutment surface characteristics represent one modifiable factor potentially influencing risk of peri-implant disease. Among risk of peri-implant disease. Among multiple considerations in abutment design, biofilm diversity performance may represent a clinically relevant benchmark.
背景：钛（TI）和钇稳定氧化锆（YSZ）是牙科种植体周围软组织界面常用的牙科材料。这些表面对细菌粘附和生物膜发展的影响可能会影响临床表现和患者对种植体周围炎症性疾病的易感性。本研究旨在评估基底材料对生物膜多样性的影响。方法：使用从三位人体捐献者处获得的斑块标本，在TI、YSZ和羟基磷灰石（HA）表面（对照）上培养生物膜。重复培养物分别生长一、二、三、六或九天。然后使用 16S rRNA 测序分析生物膜的多样性。计算每个实验组的香农多样性指数（SDI）。以成对方式相互比较微生物概况，以确定差异分数，并将其记录在距离差异矩阵中。结果共鉴定出 16 个类群，各实验组主要门类和属的相对丰度没有统计学差异。与在 TI 或 YSZ 表面上形成的生物膜相比，生长在 HA 表面上的生物膜显示出明显更高的α多样性（p<0.0001），尽管在 TI 和 YSG 表面上培养的生物膜显示出相当的多样性。贝塔多样性与基质（p=0.012）和生长期（p=0.001）的差异具有统计学意义。结论在所述条件下，生长在 TI 或 YSZ 上的生物膜的复杂性明显低于在 HA 上形成的生物膜。经粘膜种植体基台表面特征是潜在影响种植体周围疾病风险的一个可改变因素。在种植体周围疾病的风险中在基台设计的多个考虑因素中，生物膜多样性的表现可能是与临床相关的基准。
{"title":"The Influence of Hydroxyapatite, Titanium, and Yttria-Stabilized Zirconia Oxide on Diversity of Bacterial Cultures Grown from Human Dental Biofilm Specimens in an In Vitro Model","authors":"","doi":"10.54289/jdoe2400103","DOIUrl":"https://doi.org/10.54289/jdoe2400103","url":null,"abstract":"Background: Titanium (TI) and yttria stabilized-zirconia oxide (YSZ) are dental materials commonly utilized at the soft-tissue interface surrounding dental implants. The influence of these surfaces on bacterial adhesion and biofilm development may affect clinical performance and patient susceptibility to inflammatory peri-implant disease. The purpose of this study was to evaluate the influence of the substrate material on biofilm diversity. Methods: Biofilms were cultured on TI, YSZ, and hydroxyapatite (HA) surfaces (control) using plaque specimens obtained from three human donors. Duplicate cultures grew for one, two, three, six or nine days. Biofilm diversity was then analyzed using 16S rRNA sequencing. The Shannon Diversity Index (SDI) was calculated for each experimental group. Microbial profiles were intercompared in a pairwise fashion to establish dissimilarity scores, which were recorded in a distance dissimilarity matrix. Results: A total of 16 taxa were identified, and relative abundances of the predominant phyla and genera did not appear statistically different across experimental groups. Biofilms grown on HA surfaces exhibited significantly higher alpha diversity compared with those formed on TI or YSZ (p<0.0001), although biofilms cultured on TI and YSG surfaces exhibited comparable diversity. Statistically significant differences in beta diversity associated with substrate (p=0.012) and growth period (p=0.001) were detected. Conclusions: Under the conditions described, biofilms grown on TI or YSZ appeared significantly less complex than those formed on HA. Transmucosal implant abutment surface characteristics represent one modifiable factor potentially influencing risk of peri-implant disease. Among risk of peri-implant disease. Among multiple considerations in abutment design, biofilm diversity performance may represent a clinically relevant benchmark.","PeriodicalId":73703,"journal":{"name":"Journal of dentistry and oral epidemiology","volume":"63 44","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139844251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: Studies have long suggested a link between Periodontal Disease and an increased risk of other inflammatory diseases, and diverse types of cancer. The aim of the current research was to investigate the possible differences regarding the periodontal condition and tooth loss between individuals suffering from Multiple Myeloma (MM) and healthy ones. Methods: This was a population-based retrospective case-control study in which 98 MM patients and 196 matching healthy controls were interviewed and dental and oral clinically examined. The clinical indices used to define the periodontal condition for MM patients and healthy individuals concerned Probing Pocket Depth (PPD), Clinical Attachment Loss (CAL), Plaque Index (PlI), Gingival Index (GI), and number of missing teeth. Univariate and logistic regression models were carried out to assess the data analyzed. Results: Individuals with increased BMI (p=0.003, 95% CI= 2.405) who suffered from MM and those with a family history of MM (p=0.000, 95% CI=8.495), were statistically significantly different compared with the healthy ones. Moreover, GI (p=0.042, 95% CI=2.451), was statistically significantly different between MM patients and the healthy individuals after controlling for smoking and socio-economic status. Conclusion: GI was statistically significantly different between individuals who were suffered from MM and healthy individuals.
研究目的长期以来的研究表明，牙周病与其他炎症性疾病和各种癌症的风险增加之间存在联系。本研究旨在调查多发性骨髓瘤（MM）患者与健康患者在牙周状况和牙齿脱落方面可能存在的差异。研究方法这是一项基于人群的回顾性病例对照研究，对 98 名多发性骨髓瘤患者和 196 名相匹配的健康对照者进行了访谈，并进行了牙科和口腔临床检查。用于界定 MM 患者和健康人牙周状况的临床指标包括探诊袋深度（PPD）、临床附着丧失（CAL）、牙菌斑指数（PlI）、牙龈指数（GI）和缺失牙数量。对分析的数据进行了单变量和逻辑回归模型评估。结果显示与健康人相比，BMI（P=0.003，95% CI=2.405）增加的 MM 患者和有 MM 家族史的患者（P=0.000，95% CI=8.495）在统计学上有显著差异。此外，在控制了吸烟和社会经济状况后，MM 患者与健康人之间的消化道感染率（p=0.042，95% CI=2.451）在统计学上有明显差异。结论从统计学角度看，MM 患者与健康人的 GI 存在明显差异。
{"title":"Investigation of Periodontal Condition, and Tooth Loss in Multiple Myeloma Patients: A Case-Control Study","authors":"","doi":"10.54289/jdoe2400102","DOIUrl":"https://doi.org/10.54289/jdoe2400102","url":null,"abstract":"Objectives: Studies have long suggested a link between Periodontal Disease and an increased risk of other inflammatory diseases, and diverse types of cancer. The aim of the current research was to investigate the possible differences regarding the periodontal condition and tooth loss between individuals suffering from Multiple Myeloma (MM) and healthy ones. Methods: This was a population-based retrospective case-control study in which 98 MM patients and 196 matching healthy controls were interviewed and dental and oral clinically examined. The clinical indices used to define the periodontal condition for MM patients and healthy individuals concerned Probing Pocket Depth (PPD), Clinical Attachment Loss (CAL), Plaque Index (PlI), Gingival Index (GI), and number of missing teeth. Univariate and logistic regression models were carried out to assess the data analyzed. Results: Individuals with increased BMI (p=0.003, 95% CI= 2.405) who suffered from MM and those with a family history of MM (p=0.000, 95% CI=8.495), were statistically significantly different compared with the healthy ones. Moreover, GI (p=0.042, 95% CI=2.451), was statistically significantly different between MM patients and the healthy individuals after controlling for smoking and socio-economic status. Conclusion: GI was statistically significantly different between individuals who were suffered from MM and healthy individuals.","PeriodicalId":73703,"journal":{"name":"Journal of dentistry and oral epidemiology","volume":"103 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139833407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: Studies have long suggested a link between Periodontal Disease and an increased risk of other inflammatory diseases, and diverse types of cancer. The aim of the current research was to investigate the possible differences regarding the periodontal condition and tooth loss between individuals suffering from Multiple Myeloma (MM) and healthy ones. Methods: This was a population-based retrospective case-control study in which 98 MM patients and 196 matching healthy controls were interviewed and dental and oral clinically examined. The clinical indices used to define the periodontal condition for MM patients and healthy individuals concerned Probing Pocket Depth (PPD), Clinical Attachment Loss (CAL), Plaque Index (PlI), Gingival Index (GI), and number of missing teeth. Univariate and logistic regression models were carried out to assess the data analyzed. Results: Individuals with increased BMI (p=0.003, 95% CI= 2.405) who suffered from MM and those with a family history of MM (p=0.000, 95% CI=8.495), were statistically significantly different compared with the healthy ones. Moreover, GI (p=0.042, 95% CI=2.451), was statistically significantly different between MM patients and the healthy individuals after controlling for smoking and socio-economic status. Conclusion: GI was statistically significantly different between individuals who were suffered from MM and healthy individuals.
研究目的长期以来的研究表明，牙周病与其他炎症性疾病和各种癌症的风险增加之间存在联系。本研究旨在调查多发性骨髓瘤（MM）患者与健康患者在牙周状况和牙齿脱落方面可能存在的差异。研究方法这是一项基于人群的回顾性病例对照研究，对 98 名多发性骨髓瘤患者和 196 名相匹配的健康对照者进行了访谈，并进行了牙科和口腔临床检查。用于界定 MM 患者和健康人牙周状况的临床指标包括探诊袋深度（PPD）、临床附着丧失（CAL）、牙菌斑指数（PlI）、牙龈指数（GI）和缺失牙数量。对分析的数据进行了单变量和逻辑回归模型评估。结果显示与健康人相比，BMI（P=0.003，95% CI=2.405）增加的 MM 患者和有 MM 家族史的患者（P=0.000，95% CI=8.495）在统计学上有显著差异。此外，在控制了吸烟和社会经济状况后，MM 患者与健康人之间的消化道感染率（p=0.042，95% CI=2.451）在统计学上有明显差异。结论从统计学角度看，MM 患者与健康人的 GI 存在明显差异。
{"title":"Investigation of Periodontal Condition, and Tooth Loss in Multiple Myeloma Patients: A Case-Control Study","authors":"","doi":"10.54289/jdoe2400102","DOIUrl":"https://doi.org/10.54289/jdoe2400102","url":null,"abstract":"Objectives: Studies have long suggested a link between Periodontal Disease and an increased risk of other inflammatory diseases, and diverse types of cancer. The aim of the current research was to investigate the possible differences regarding the periodontal condition and tooth loss between individuals suffering from Multiple Myeloma (MM) and healthy ones. Methods: This was a population-based retrospective case-control study in which 98 MM patients and 196 matching healthy controls were interviewed and dental and oral clinically examined. The clinical indices used to define the periodontal condition for MM patients and healthy individuals concerned Probing Pocket Depth (PPD), Clinical Attachment Loss (CAL), Plaque Index (PlI), Gingival Index (GI), and number of missing teeth. Univariate and logistic regression models were carried out to assess the data analyzed. Results: Individuals with increased BMI (p=0.003, 95% CI= 2.405) who suffered from MM and those with a family history of MM (p=0.000, 95% CI=8.495), were statistically significantly different compared with the healthy ones. Moreover, GI (p=0.042, 95% CI=2.451), was statistically significantly different between MM patients and the healthy individuals after controlling for smoking and socio-economic status. Conclusion: GI was statistically significantly different between individuals who were suffered from MM and healthy individuals.","PeriodicalId":73703,"journal":{"name":"Journal of dentistry and oral epidemiology","volume":"72 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139893180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: In periodontics, interest in use of autologous blood-derived products (ABPs) has increased due to demonstrated safety, enhanced initial healing, and for some applications, superior clinical outcomes. Periodontists commonly place peripheral intravenous catheters for moderate sedation, thus encountering opportunities to utilize ABPs routinely. The purpose of this report is to describe a safe blood collection technique for ABP preparation and define typical blood volume requirements for periodontal procedures. Methods: Five cases requiring various amounts of liquid and membrane-formed platelet-rich fibrin are presented. Case 1 involves treatment of an infrabony periodontal defect. Case 2 illustrates alveolar ridge preservation at a maxillary right second premolar site. Case 3 demonstrates repair of a defect related to nasopalatine duct cyst removal. Cases 4 and 5 illustrate the use of PRF in sinus elevation and root coverage, respectively. Results: Use of PRF in the presented cases added minimal procedural time and expense. Blood samples varied from 20 to 60 ml in volume. There were no complications related to blood collection or use of PRF. Each patient reported minimal discomfort limited to the first few postoperative days. Favorable early healing was observed in each case. Conclusions: The blood collection method described in this report, which is consistent with published standards of practice, necessitates few additional steps and supplies for practitioners already placing peripheral intravenous catheters. Blood volumes necessary for typical procedures in periodontics are safe and well below maximum attainable samples.
{"title":"Blood Collection for Autologous Blood-Derived Product Preparation: Technique and Application","authors":"","doi":"10.54289/jdoe2400101","DOIUrl":"https://doi.org/10.54289/jdoe2400101","url":null,"abstract":"Background: In periodontics, interest in use of autologous blood-derived products (ABPs) has increased due to demonstrated safety, enhanced initial healing, and for some applications, superior clinical outcomes. Periodontists commonly place peripheral intravenous catheters for moderate sedation, thus encountering opportunities to utilize ABPs routinely. The purpose of this report is to describe a safe blood collection technique for ABP preparation and define typical blood volume requirements for periodontal procedures. Methods: Five cases requiring various amounts of liquid and membrane-formed platelet-rich fibrin are presented. Case 1 involves treatment of an infrabony periodontal defect. Case 2 illustrates alveolar ridge preservation at a maxillary right second premolar site. Case 3 demonstrates repair of a defect related to nasopalatine duct cyst removal. Cases 4 and 5 illustrate the use of PRF in sinus elevation and root coverage, respectively. Results: Use of PRF in the presented cases added minimal procedural time and expense. Blood samples varied from 20 to 60 ml in volume. There were no complications related to blood collection or use of PRF. Each patient reported minimal discomfort limited to the first few postoperative days. Favorable early healing was observed in each case. Conclusions: The blood collection method described in this report, which is consistent with published standards of practice, necessitates few additional steps and supplies for practitioners already placing peripheral intravenous catheters. Blood volumes necessary for typical procedures in periodontics are safe and well below maximum attainable samples.","PeriodicalId":73703,"journal":{"name":"Journal of dentistry and oral epidemiology","volume":"15 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139445640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evidence-based algorithms guiding treatment of traumatic dentoalveolar injuries prescribe specific interventions in the presence of various sets of historical and clinical cues. However, the staging of dental implant placement in post-traumatic rehabilitation—indeed, whether to consider implant therapy at all—remains more art than science, prior authors cautioning that universal rules do not apply. The purpose of this report is to present treatment approaches applied in three traumatic episodes involving the anterior maxilla. Three patients presented to the Department of Periodontics, Army Postgraduate Dental School, Postgraduate Dental College, Fort Eisenhower, GA, USA, following traumatic injuries to the anterior maxilla with varying degrees of severity. In two cases, central incisors were replaced using immediate implants and immediate provisionalization (IIPP). At one IIPP site, extraction was delayed for eight weeks to permit healing of an alveolar fracture. In the third case, the patient received a non-implant rehabilitation due to severe alveolar destruction. Both patients receiving IIPP expressed satisfaction with immediate esthetics, and in both cases, the provisional restoration prevented extraction-related soft tissue collapse. Trauma adds an element of uncertainty to the technically demanding task of implant placement in the esthetic zone. When appropriate, IIPP in the post-traumatic rehabilitation of the anterior maxilla may mitigate some of the known biopsychosocial consequences of oral trauma and facilitate development of favorable mucosal and osseous architecture at the site. Individualized treatment planning is critically important due to wide variability in site characteristics and injury complexity.
{"title":"Dental Implant Treatment Planning in the Post-Traumatic Rehabilitation of the Anterior Maxilla: A Report of Three Cases","authors":"","doi":"10.54289/jdoe2300103","DOIUrl":"https://doi.org/10.54289/jdoe2300103","url":null,"abstract":"Evidence-based algorithms guiding treatment of traumatic dentoalveolar injuries prescribe specific interventions in the presence of various sets of historical and clinical cues. However, the staging of dental implant placement in post-traumatic rehabilitation—indeed, whether to consider implant therapy at all—remains more art than science, prior authors cautioning that universal rules do not apply. The purpose of this report is to present treatment approaches applied in three traumatic episodes involving the anterior maxilla. Three patients presented to the Department of Periodontics, Army Postgraduate Dental School, Postgraduate Dental College, Fort Eisenhower, GA, USA, following traumatic injuries to the anterior maxilla with varying degrees of severity. In two cases, central incisors were replaced using immediate implants and immediate provisionalization (IIPP). At one IIPP site, extraction was delayed for eight weeks to permit healing of an alveolar fracture. In the third case, the patient received a non-implant rehabilitation due to severe alveolar destruction. Both patients receiving IIPP expressed satisfaction with immediate esthetics, and in both cases, the provisional restoration prevented extraction-related soft tissue collapse. Trauma adds an element of uncertainty to the technically demanding task of implant placement in the esthetic zone. When appropriate, IIPP in the post-traumatic rehabilitation of the anterior maxilla may mitigate some of the known biopsychosocial consequences of oral trauma and facilitate development of favorable mucosal and osseous architecture at the site. Individualized treatment planning is critically important due to wide variability in site characteristics and injury complexity.","PeriodicalId":73703,"journal":{"name":"Journal of dentistry and oral epidemiology","volume":"33 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138604005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Immediate implant placement into a molar extraction socket may hasten return to masticatory function and reduce overall treatment time. Placement of a graft or biomaterial in the peri-implant gap defect (PGD) has been associated with superior treatment outcomes. The purpose of this report is to present four cases demonstrating use of laser-generated blood clots to stabilize freeze-dried bone allografts (FDBAs) at molar immediate implant sites. Methods: Four patients with non-restorable mandibular first molars presented to the Department of Periodontics, Army Postgraduate Dental School, Uniformed Services University, Fort Eisenhower, GA, USA. The hopeless teeth were extracted without flap reflection, and dental implants were installed in each socket. FDBAs were applied in the PGDs. In one case, a cover screw was utilized, and the implant was submerged under a laser-generated clot. In the remaining cases, transmucosal healing abutments were installed. Results: Favorable healing was observed in all cases, each patient reporting minimal discomfort limited to the first two postoperative days. At the submerged implant site, > 2 mm buccal bone thickness was noted at re-entry. In the remaining cases, keratinized peri-implant mucosa was in contact with the healing abutment at the one-week follow-up appointment. All implants exhibited interproximal radiographic bone levels coronal to the first implant thread at every follow-up assessment. Conclusions: Whether infrared lasers enhance healing at immediate implant sites remains an open question in implantology. However, the presented cases demonstrate that a neodymium-doped yttrium aluminum garnet laser can reliably stabilize particulate bone allografts in PGDs at immediate implant sites exhibiting large horizontal defect dimensions.
{"title":"Preservation of Alveolar Dimensions at Molar Immediate Implant Sites Using Laser-Assisted Clot Stabilization: A Report of Four Consecutive Cases with One to Three Years of Follow","authors":"","doi":"10.54289/jdoe2300102","DOIUrl":"https://doi.org/10.54289/jdoe2300102","url":null,"abstract":"Objective: Immediate implant placement into a molar extraction socket may hasten return to masticatory function and reduce overall treatment time. Placement of a graft or biomaterial in the peri-implant gap defect (PGD) has been associated with superior treatment outcomes. The purpose of this report is to present four cases demonstrating use of laser-generated blood clots to stabilize freeze-dried bone allografts (FDBAs) at molar immediate implant sites. Methods: Four patients with non-restorable mandibular first molars presented to the Department of Periodontics, Army Postgraduate Dental School, Uniformed Services University, Fort Eisenhower, GA, USA. The hopeless teeth were extracted without flap reflection, and dental implants were installed in each socket. FDBAs were applied in the PGDs. In one case, a cover screw was utilized, and the implant was submerged under a laser-generated clot. In the remaining cases, transmucosal healing abutments were installed. Results: Favorable healing was observed in all cases, each patient reporting minimal discomfort limited to the first two postoperative days. At the submerged implant site, > 2 mm buccal bone thickness was noted at re-entry. In the remaining cases, keratinized peri-implant mucosa was in contact with the healing abutment at the one-week follow-up appointment. All implants exhibited interproximal radiographic bone levels coronal to the first implant thread at every follow-up assessment. Conclusions: Whether infrared lasers enhance healing at immediate implant sites remains an open question in implantology. However, the presented cases demonstrate that a neodymium-doped yttrium aluminum garnet laser can reliably stabilize particulate bone allografts in PGDs at immediate implant sites exhibiting large horizontal defect dimensions.","PeriodicalId":73703,"journal":{"name":"Journal of dentistry and oral epidemiology","volume":"4 12","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136228858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral health is one of the significant determinants of general health, happiness and life quality. Dental caries, oro-dental trauma, periodontal disease and birth abnormalities including cleft lip and palate are among the reasons for tooth loss. High prevalence of tooth loss is the major cause of morbidity due to oral diseases in low and middle-income countries (WHO report,). Polymethyl-methacrylate (PMMA) bases are the preferred option for replacing missing teeth because of its biocompatibility, stability, easy handling, and low toxicity. Though PMMA is the most preferable material for denture preparation, lack of antimicrobial potential, thermal conductivity and radiopacity limits its diverse application. Seminal findings have shown, incorporation of certain nanoparticles may increase the antimicrobial potential, thermal conductivity and radiopacity of the PMMA. In the current review, we have elucidated light on the antimicrobial potential of PMMA based on the available information. We also focused on the current advancement and strategy regarding the improvement of antimicrobial potential of PMMA and other base materials. The information has been collected from published article available on PubMed up to 31 May 2022. The available studies supported that the antimicrobial property of PMMA can be improved by incorporation of nanoparticles such as graphene silver nanoparticles, TiO2, ZnO, SiO2/Ag These nanoparticles have been found to be effective against Staphylococcus aureus, Streptococcus mutans, Candida albicans, Escherichia coli, Pseudomonas fuorescense. In addition to nanoparticles, inert coating materials such as ammonium chitosan, sodium alginate, bioactive glass, chlorhexidine and organoselenium can be incorporated to enhance the antimicrobial properties of PMMA base denture material as well as inert coating material can be used to prevent the metal ion toxicity and a probable vehicle to leach the desired product at targeted site.
{"title":"Nanoparticles and Inert Coating Materials: A Potential Enhancer of Antimicrobial Property of Polymethyl-Methacrylate (PMMA) Based Denture","authors":"","doi":"10.54289/jdoe2300101","DOIUrl":"https://doi.org/10.54289/jdoe2300101","url":null,"abstract":"Oral health is one of the significant determinants of general health, happiness and life quality. Dental caries, oro-dental trauma, periodontal disease and birth abnormalities including cleft lip and palate are among the reasons for tooth loss. High prevalence of tooth loss is the major cause of morbidity due to oral diseases in low and middle-income countries (WHO report,). Polymethyl-methacrylate (PMMA) bases are the preferred option for replacing missing teeth because of its biocompatibility, stability, easy handling, and low toxicity. Though PMMA is the most preferable material for denture preparation, lack of antimicrobial potential, thermal conductivity and radiopacity limits its diverse application. Seminal findings have shown, incorporation of certain nanoparticles may increase the antimicrobial potential, thermal conductivity and radiopacity of the PMMA. In the current review, we have elucidated light on the antimicrobial potential of PMMA based on the available information. We also focused on the current advancement and strategy regarding the improvement of antimicrobial potential of PMMA and other base materials. The information has been collected from published article available on PubMed up to 31 May 2022. The available studies supported that the antimicrobial property of PMMA can be improved by incorporation of nanoparticles such as graphene silver nanoparticles, TiO2, ZnO, SiO2/Ag These nanoparticles have been found to be effective against Staphylococcus aureus, Streptococcus mutans, Candida albicans, Escherichia coli, Pseudomonas fuorescense. In addition to nanoparticles, inert coating materials such as ammonium chitosan, sodium alginate, bioactive glass, chlorhexidine and organoselenium can be incorporated to enhance the antimicrobial properties of PMMA base denture material as well as inert coating material can be used to prevent the metal ion toxicity and a probable vehicle to leach the desired product at targeted site.","PeriodicalId":73703,"journal":{"name":"Journal of dentistry and oral epidemiology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42218704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Epidemiologic studies provide strong evidence that chronic psychosocial stress and depression increase the risk of several systemic diseases and disorders. The current research aimed to investigate the association between stress, and depression with Periodontal Disease indices. Material and Methods: The study counted with 280 individuals, males and females, 40–65 years of age, and were collected through a clinical examination and a modified standardized questionnaire. Case group included 140 individuals suffering from periodontal disease and control group consisted of 140 individuals with no history of periodontal disease. Psychological factors assessment included the following inventories, Beck Anxiety Inventory (BAI), and Beck Depression Inventory (BDI). Periodontal disease was assessed based on the following indices, Probing Pocket Depth (PPD), Clinical Attachment Loss (CAL), Gingival Index (GI) and Bleeding on Probing (BOP). Univariate and multivariate logistic regression analyses were carried out to compare cases and controls. Results: Mean probing depth and clinical attachment level were 4.60 ± 0.32 mm and 4.72 ± 1.12 mm in cases and 2.10 ± 0.50 mm and 1.86 ± 0.31 mm in controls, respectively (p < 0.05 and p< 0.01, respectively). Multivariate logistic regression model, controlling for confounding factors, demonstrated significant association between BAI and BDI with deeper periodontal pockets [p = 0.028 and p = 0.032, respectively], and moderate/severe CAL [p = 0.018 and p = 0.048, respectively]. The outcomes also revealed no significant associations between the mentioned psychological parameters with gingival inflammation (GI) and BOP. Those associations were confirmed after adjusting for possible confounders such as smoking, educational and socio-economic status. Conclusion: Within the limits, the current research revealed significant associations between BAI and BDI and deeper periodontal pockets and moderate/severe CAL.
{"title":"Investigation of the Association Between Psychological Parameters and Periodontal Disease in a Greek Adult Population: A Case - Control Study","authors":"","doi":"10.54289/jdoe2200106","DOIUrl":"https://doi.org/10.54289/jdoe2200106","url":null,"abstract":"Objective: Epidemiologic studies provide strong evidence that chronic psychosocial stress and depression increase the risk of several systemic diseases and disorders. The current research aimed to investigate the association between stress, and depression with Periodontal Disease indices. Material and Methods: The study counted with 280 individuals, males and females, 40–65 years of age, and were collected through a clinical examination and a modified standardized questionnaire. Case group included 140 individuals suffering from periodontal disease and control group consisted of 140 individuals with no history of periodontal disease. Psychological factors assessment included the following inventories, Beck Anxiety Inventory (BAI), and Beck Depression Inventory (BDI). Periodontal disease was assessed based on the following indices, Probing Pocket Depth (PPD), Clinical Attachment Loss (CAL), Gingival Index (GI) and Bleeding on Probing (BOP). Univariate and multivariate logistic regression analyses were carried out to compare cases and controls. Results: Mean probing depth and clinical attachment level were 4.60 ± 0.32 mm and 4.72 ± 1.12 mm in cases and 2.10 ± 0.50 mm and 1.86 ± 0.31 mm in controls, respectively (p < 0.05 and p< 0.01, respectively). Multivariate logistic regression model, controlling for confounding factors, demonstrated significant association between BAI and BDI with deeper periodontal pockets [p = 0.028 and p = 0.032, respectively], and moderate/severe CAL [p = 0.018 and p = 0.048, respectively]. The outcomes also revealed no significant associations between the mentioned psychological parameters with gingival inflammation (GI) and BOP. Those associations were confirmed after adjusting for possible confounders such as smoking, educational and socio-economic status. Conclusion: Within the limits, the current research revealed significant associations between BAI and BDI and deeper periodontal pockets and moderate/severe CAL.","PeriodicalId":73703,"journal":{"name":"Journal of dentistry and oral epidemiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43736332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The aim of the current report was to examine the association between indices of oral health condition and cardiovascular disease in an adult Greek population. Material and Methods:1,026 individuals derived from two medical and one dental practice consisted the study sample. The participants underwent an oral and dental clinical examination and answered a questionnaire regarding oral health, dental care habits, cardiovascular disease, socio-economic and educational status. Odd ratios for all cardiovascular diseases (CVD) and the subgroup stroke, myocardial infarction and hypertension were assessed with a logistic regression model adjusted for age, gender, smoking, educational and socio-economic status. Results: After carrying out the logistic regression analysis model, an association between moderate/severe gingival inflammation (GI) and all CVD in general was observed (p=0.04, OR=1.87), and hypertension (p=0.03, OR= 1.73). There was also an association between severe PlI and all CVD (p=0.022, OR=1.78), and hypertension (p=0.015, OR=1.88). Moreover, an association was found between BOP all CVD (p=0.01, OR= 1.89), and hypertension (p=0.005, OR= 1.98). Conclusion: The results indicated that oral health and, especially gingival inflammation (GI), plaque accumulation (PlI) and presence of bleeding on probing (BOP) were associated with CVD and hypertension.
{"title":"Oral Health Condition and Cardiovascular Disease in Greece: Results of a Questionnaire Research","authors":"","doi":"10.54289/jdoe2200105","DOIUrl":"https://doi.org/10.54289/jdoe2200105","url":null,"abstract":"Objective: The aim of the current report was to examine the association between indices of oral health condition and cardiovascular disease in an adult Greek population. Material and Methods:1,026 individuals derived from two medical and one dental practice consisted the study sample. The participants underwent an oral and dental clinical examination and answered a questionnaire regarding oral health, dental care habits, cardiovascular disease, socio-economic and educational status. Odd ratios for all cardiovascular diseases (CVD) and the subgroup stroke, myocardial infarction and hypertension were assessed with a logistic regression model adjusted for age, gender, smoking, educational and socio-economic status. Results: After carrying out the logistic regression analysis model, an association between moderate/severe gingival inflammation (GI) and all CVD in general was observed (p=0.04, OR=1.87), and hypertension (p=0.03, OR= 1.73). There was also an association between severe PlI and all CVD (p=0.022, OR=1.78), and hypertension (p=0.015, OR=1.88). Moreover, an association was found between BOP all CVD (p=0.01, OR= 1.89), and hypertension (p=0.005, OR= 1.98). Conclusion: The results indicated that oral health and, especially gingival inflammation (GI), plaque accumulation (PlI) and presence of bleeding on probing (BOP) were associated with CVD and hypertension.","PeriodicalId":73703,"journal":{"name":"Journal of dentistry and oral epidemiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47417233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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